KR20220153606A - 박테리아 숙주 균주 - Google Patents

박테리아 숙주 균주 Download PDF

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Publication number
KR20220153606A
KR20220153606A KR1020227034771A KR20227034771A KR20220153606A KR 20220153606 A KR20220153606 A KR 20220153606A KR 1020227034771 A KR1020227034771 A KR 1020227034771A KR 20227034771 A KR20227034771 A KR 20227034771A KR 20220153606 A KR20220153606 A KR 20220153606A
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South Korea
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engineered
host cell
coli host
seq
vector
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KR1020227034771A
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Korean (ko)
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제임스 에이. 윌리엄스
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네이쳐 테크놀로지 코포레이션
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Publication of KR20220153606A publication Critical patent/KR20220153606A/ko
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    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041—Use of virus, viral particle or viral elements as a vector
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15051—Methods of production or purification of viral material
    • C12N2740/15052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
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    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151—Methods of production or purification of viral material
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    • C—CHEMISTRY; METALLURGY
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    • C12N2820/00—Vectors comprising a special origin of replication system
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Bioinformatics & Cheminformatics (AREA)
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  • Wood Science & Technology (AREA)
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  • General Engineering & Computer Science (AREA)
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  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020227034771A 2020-03-11 2021-03-11 박테리아 숙주 균주 Pending KR20220153606A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062988223P 2020-03-11 2020-03-11
US62/988,223 2020-03-11
PCT/US2021/022002 WO2021183827A2 (en) 2020-03-11 2021-03-11 Bacterial host strains

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Publication Number Publication Date
KR20220153606A true KR20220153606A (ko) 2022-11-18

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KR1020227034771A Pending KR20220153606A (ko) 2020-03-11 2021-03-11 박테리아 숙주 균주

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US (1) US20230132250A1 (enExample)
EP (1) EP4118213A4 (enExample)
JP (2) JP7833134B2 (enExample)
KR (1) KR20220153606A (enExample)
CN (1) CN115461463A (enExample)
AU (1) AU2021233908B2 (enExample)
CA (1) CA3170890A1 (enExample)
WO (1) WO2021183827A2 (enExample)

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EP4453181A4 (en) * 2021-12-20 2025-12-24 Aldevron Llc GENE THERAPY VECTOR PRODUCTION IN MODIFIED BACTERIA
CN115851795B (zh) * 2022-07-19 2023-09-01 广州派真生物技术有限公司 一种高产质粒、其构建方法及其应用
CN116496962A (zh) * 2023-02-10 2023-07-28 台州学院 一种假尿苷工程菌及其应用、生产假尿苷的方法
CN120981563A (zh) * 2023-03-24 2025-11-18 南京金斯瑞生物科技有限公司 一种提升质粒稳定性的宿主细胞
CN121693570A (zh) * 2023-06-21 2026-03-17 阿尔德夫隆有限责任公司 基因治疗载体及其产生和使用方法
JPWO2025041806A1 (enExample) * 2023-08-22 2025-02-27
DE102023134327A1 (de) * 2023-12-07 2025-06-12 Universität Bielefeld, Körperschaft des öffentlichen Rechts Vermehrung von Plasmiden, die mindestens einen Inverted Repeat enthalten
WO2025122955A1 (en) * 2023-12-08 2025-06-12 University Of Massachusetts Delivery of oncolytic viruses with engineered salmonella
WO2025231315A2 (en) 2024-05-03 2025-11-06 Aldevron, L.L.C. Bacterial host strains

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DE19633698A1 (de) 1996-08-21 1998-02-26 Lubitz Werner Prof Dr Neue Systeme zur Regulation der Genexpression
AU2002306849A1 (en) * 2001-03-21 2002-10-08 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
EP1781800B1 (en) 2004-08-19 2013-06-19 Nature Technology Corp. Process for plasmid dna fermentation
US9550998B2 (en) 2012-08-29 2017-01-24 Nature Technology Corporation DNA plasmids with improved expression
AU2019240068B2 (en) 2018-03-21 2025-03-13 Aldevron, L.L.C. Viral and non-viral nanoplasmid vectors with improved production
CN110016459B (zh) * 2019-04-29 2021-03-19 江南大学 一种生产β-丙氨酸的重组大肠杆菌及其厌氧发酵的方法

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WO2021183827A2 (en) 2021-09-16
EP4118213A2 (en) 2023-01-18
JP7833134B2 (ja) 2026-03-19
JP2026048673A (ja) 2026-03-17
WO2021183827A3 (en) 2021-10-14
US20230132250A1 (en) 2023-04-27
CN115461463A (zh) 2022-12-09
JP2023517682A (ja) 2023-04-26
EP4118213A4 (en) 2024-04-17
CA3170890A1 (en) 2021-09-16
AU2021233908A1 (en) 2022-09-29
AU2021233908B2 (en) 2026-07-02

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