KR20220136407A - 생물학적 샘플 내 헤모글로빈을 검출하기 위한 그래핀-기반 센서 - Google Patents

생물학적 샘플 내 헤모글로빈을 검출하기 위한 그래핀-기반 센서 Download PDF

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KR20220136407A
KR20220136407A KR1020227030390A KR20227030390A KR20220136407A KR 20220136407 A KR20220136407 A KR 20220136407A KR 1020227030390 A KR1020227030390 A KR 1020227030390A KR 20227030390 A KR20227030390 A KR 20227030390A KR 20220136407 A KR20220136407 A KR 20220136407A
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graphene layer
sample
hemoglobin
functionalized
sensor
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Korean (ko)
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나말 나와나
메흐디 아베디
레자 몰라아가바바
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그래핀-디엑스, 아이엔씨.
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
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    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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    • G01N33/545—Synthetic resin
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
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    • G01N33/57484—
    • G—PHYSICS
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57535—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
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    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/795—Porphyrin- or corrin-ring-containing peptides
    • G01N2333/805—Haemoglobins; Myoglobins

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  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
KR1020227030390A 2020-02-06 2021-02-08 생물학적 샘플 내 헤모글로빈을 검출하기 위한 그래핀-기반 센서 Ceased KR20220136407A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062970919P 2020-02-06 2020-02-06
US62/970,919 2020-02-06
PCT/US2021/017082 WO2021159074A1 (en) 2020-02-06 2021-02-08 Graphene-based sensor for detecting hemoglobin in a biological sample

Publications (1)

Publication Number Publication Date
KR20220136407A true KR20220136407A (ko) 2022-10-07

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US (1) US20210247409A1 (https=)
EP (1) EP4100739A1 (https=)
JP (1) JP2023513543A (https=)
KR (1) KR20220136407A (https=)
CN (1) CN115917318A (https=)
AU (1) AU2021216478A1 (https=)
CA (1) CA3170353A1 (https=)
WO (1) WO2021159074A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12546746B2 (en) * 2021-05-05 2026-02-10 Ekidna Sensing Inc. Systems and devices for estimating substance concentration
US20230182133A1 (en) * 2021-12-01 2023-06-15 Graphene-Dx. Inc. Systems and methods for processing and testing biological samples
WO2025024598A1 (en) * 2023-07-24 2025-01-30 The Regents Of The University Of California Biomarker detection using graphene field effect transistor sensor arrays and multichannel data acquisition

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Publication number Priority date Publication date Assignee Title
US5198365A (en) * 1987-02-04 1993-03-30 International Immunoassay Laboratories, Inc. Fecal sample immunoassay method testing for hemoglobin
KR20110113610A (ko) * 2008-12-05 2011-10-17 나노아이브이디, 인크. 현장진단 분석기를 위한 미세유체 기반의 랩온어 테스트 카드
US8702931B2 (en) * 2011-04-18 2014-04-22 Indian Institute Of Science Low cost electrochemical disposable sensor for measuring glycated hemoglobin
EP4234722A3 (en) 2014-03-31 2023-09-20 Mayo Foundation for Medical Education and Research Detecting colorectal neoplasm
US10782285B2 (en) * 2014-10-03 2020-09-22 Rite Taste, LLC Device and method for chemical analysis
US9664674B2 (en) * 2014-10-03 2017-05-30 Rite Taste, LLC Device and method for chemical analysis
US10335787B2 (en) * 2014-10-16 2019-07-02 The General Hospital Corporation Specimen acceptance devices and attachable disposable assay cartridges
FR3035317B1 (fr) * 2015-04-24 2019-06-14 Maat Pharma Dispositif de prelevement de micro-organismes, kit de prelevement comprenant un tel dispositif et procede de prelevement mettant en œuvre un tel dispositif
US20180317892A1 (en) * 2015-10-03 2018-11-08 George Catlin Stool collection, containment, and specimen disbursement system
KR101906447B1 (ko) * 2016-07-20 2018-10-11 한국과학기술연구원 전계효과 대장암 센서
US10456787B2 (en) * 2016-08-11 2019-10-29 Instrumentation Laboratory Company Reagent component dispensing caps for reagent containers used in automated clinical analyzers
KR20190072520A (ko) * 2016-10-24 2019-06-25 도레이 카부시키가이샤 반도체 센서 및 그의 제조 방법, 그리고 복합 센서
CN108241012B (zh) * 2016-12-27 2020-07-10 中国科学院金属研究所 基于石墨烯的血红蛋白传感器电极的制备方法及其应用
AU2019275116A1 (en) * 2018-05-24 2021-01-07 Graphene-Dx, Inc. A functionalized sensor for detection of biomarkers
CN109097471A (zh) * 2018-08-21 2018-12-28 杭州和壹基因科技有限公司 一种用于结直肠癌及癌前病变检测的试剂盒及其使用方法

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EP4100739A1 (en) 2022-12-14
CA3170353A1 (en) 2021-08-12
US20210247409A1 (en) 2021-08-12
WO2021159074A1 (en) 2021-08-12
JP2023513543A (ja) 2023-03-31
AU2021216478A1 (en) 2022-09-08
CN115917318A (zh) 2023-04-04

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