JP2023513543A - 生体試料中のヘモグロビンを検出するためのグラフェンベースのセンサ - Google Patents
生体試料中のヘモグロビンを検出するためのグラフェンベースのセンサ Download PDFInfo
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- JP2023513543A JP2023513543A JP2022548190A JP2022548190A JP2023513543A JP 2023513543 A JP2023513543 A JP 2023513543A JP 2022548190 A JP2022548190 A JP 2022548190A JP 2022548190 A JP2022548190 A JP 2022548190A JP 2023513543 A JP2023513543 A JP 2023513543A
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- G—PHYSICS
- G01—MEASURING; TESTING
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/726—Devices
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Rigid containers without fluid transport within
- B01L3/5082—Test tubes per se
- B01L3/50825—Closing or opening means, corks, bungs
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/545—Synthetic resin
- G01N33/547—Synthetic resin with antigen or antibody attached to the carrier via a bridging agent
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57535—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Rigid containers without fluid transport within
- B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/795—Porphyrin- or corrin-ring-containing peptides
- G01N2333/805—Haemoglobins; Myoglobins
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062970919P | 2020-02-06 | 2020-02-06 | |
| US62/970,919 | 2020-02-06 | ||
| PCT/US2021/017082 WO2021159074A1 (en) | 2020-02-06 | 2021-02-08 | Graphene-based sensor for detecting hemoglobin in a biological sample |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023513543A true JP2023513543A (ja) | 2023-03-31 |
| JP2023513543A5 JP2023513543A5 (https=) | 2024-02-14 |
| JPWO2021159074A5 JPWO2021159074A5 (https=) | 2024-02-14 |
Family
ID=74798111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022548190A Pending JP2023513543A (ja) | 2020-02-06 | 2021-02-08 | 生体試料中のヘモグロビンを検出するためのグラフェンベースのセンサ |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20210247409A1 (https=) |
| EP (1) | EP4100739A1 (https=) |
| JP (1) | JP2023513543A (https=) |
| KR (1) | KR20220136407A (https=) |
| CN (1) | CN115917318A (https=) |
| AU (1) | AU2021216478A1 (https=) |
| CA (1) | CA3170353A1 (https=) |
| WO (1) | WO2021159074A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12546746B2 (en) * | 2021-05-05 | 2026-02-10 | Ekidna Sensing Inc. | Systems and devices for estimating substance concentration |
| US20230182133A1 (en) * | 2021-12-01 | 2023-06-15 | Graphene-Dx. Inc. | Systems and methods for processing and testing biological samples |
| WO2025024598A1 (en) * | 2023-07-24 | 2025-01-30 | The Regents Of The University Of California | Biomarker detection using graphene field effect transistor sensor arrays and multichannel data acquisition |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012511156A (ja) * | 2008-12-05 | 2012-05-17 | ナノアイヴイディー,インコーポレイテッド | ポイント・オブ・ケア分析器用マイクロ流体ベースのラボオンテストカード |
| US20120261257A1 (en) * | 2011-04-18 | 2012-10-18 | Indian Institute Of Science | Low cost electrochemical disposable sensor for measuring glycated hemoglobin |
| US20160097764A1 (en) * | 2014-10-03 | 2016-04-07 | Rite Taste, LLC | Device and method for chemical analysis |
| WO2018079314A1 (ja) * | 2016-10-24 | 2018-05-03 | 東レ株式会社 | 半導体センサおよびその製造方法、ならびに複合センサ |
| JP2019525177A (ja) * | 2016-08-11 | 2019-09-05 | インストゥルメンテーション ラボラトリー カンパニー | 自動臨床分析装置内で使用される試薬容器用の試薬組成物分注キャップ |
| WO2019227069A1 (en) * | 2018-05-24 | 2019-11-28 | Rite Taste, LLC | A functionalized sensor for detection of biomarkers |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5198365A (en) * | 1987-02-04 | 1993-03-30 | International Immunoassay Laboratories, Inc. | Fecal sample immunoassay method testing for hemoglobin |
| EP4234722A3 (en) | 2014-03-31 | 2023-09-20 | Mayo Foundation for Medical Education and Research | Detecting colorectal neoplasm |
| US10782285B2 (en) * | 2014-10-03 | 2020-09-22 | Rite Taste, LLC | Device and method for chemical analysis |
| US10335787B2 (en) * | 2014-10-16 | 2019-07-02 | The General Hospital Corporation | Specimen acceptance devices and attachable disposable assay cartridges |
| FR3035317B1 (fr) * | 2015-04-24 | 2019-06-14 | Maat Pharma | Dispositif de prelevement de micro-organismes, kit de prelevement comprenant un tel dispositif et procede de prelevement mettant en œuvre un tel dispositif |
| US20180317892A1 (en) * | 2015-10-03 | 2018-11-08 | George Catlin | Stool collection, containment, and specimen disbursement system |
| KR101906447B1 (ko) * | 2016-07-20 | 2018-10-11 | 한국과학기술연구원 | 전계효과 대장암 센서 |
| CN108241012B (zh) * | 2016-12-27 | 2020-07-10 | 中国科学院金属研究所 | 基于石墨烯的血红蛋白传感器电极的制备方法及其应用 |
| CN109097471A (zh) * | 2018-08-21 | 2018-12-28 | 杭州和壹基因科技有限公司 | 一种用于结直肠癌及癌前病变检测的试剂盒及其使用方法 |
-
2021
- 2021-02-08 CA CA3170353A patent/CA3170353A1/en active Pending
- 2021-02-08 KR KR1020227030390A patent/KR20220136407A/ko not_active Ceased
- 2021-02-08 EP EP21708890.5A patent/EP4100739A1/en active Pending
- 2021-02-08 JP JP2022548190A patent/JP2023513543A/ja active Pending
- 2021-02-08 WO PCT/US2021/017082 patent/WO2021159074A1/en not_active Ceased
- 2021-02-08 AU AU2021216478A patent/AU2021216478A1/en not_active Abandoned
- 2021-02-08 CN CN202180024705.5A patent/CN115917318A/zh active Pending
- 2021-02-08 US US17/170,439 patent/US20210247409A1/en not_active Abandoned
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012511156A (ja) * | 2008-12-05 | 2012-05-17 | ナノアイヴイディー,インコーポレイテッド | ポイント・オブ・ケア分析器用マイクロ流体ベースのラボオンテストカード |
| US20120261257A1 (en) * | 2011-04-18 | 2012-10-18 | Indian Institute Of Science | Low cost electrochemical disposable sensor for measuring glycated hemoglobin |
| US20160097764A1 (en) * | 2014-10-03 | 2016-04-07 | Rite Taste, LLC | Device and method for chemical analysis |
| JP2019525177A (ja) * | 2016-08-11 | 2019-09-05 | インストゥルメンテーション ラボラトリー カンパニー | 自動臨床分析装置内で使用される試薬容器用の試薬組成物分注キャップ |
| WO2018079314A1 (ja) * | 2016-10-24 | 2018-05-03 | 東レ株式会社 | 半導体センサおよびその製造方法、ならびに複合センサ |
| WO2019227069A1 (en) * | 2018-05-24 | 2019-11-28 | Rite Taste, LLC | A functionalized sensor for detection of biomarkers |
Non-Patent Citations (2)
| Title |
|---|
| GITA V SORAYA, 外9名: "A Label-Free, Quantitative Fecal HemoglobinDetection Platform for Colorectal Cancer Screening", BIOSENSORS, vol. 第7巻第19号, JPN6024035233, 2017, pages 1 - 11, ISSN: 0005731622 * |
| SIVA RAMA KRISHNA V, 外4名: "Detection of GlycatedHemoglobin using3-AminoPhenylboronic acid modified Graphene Oxide", IEEE/NIH LIFE SCIENCESYSTEMS AND APPLICATIONS WORKSHOP (LISSA), JPN6024035234, 2011, pages 1 - 4, ISSN: 0005602029 * |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20220136407A (ko) | 2022-10-07 |
| EP4100739A1 (en) | 2022-12-14 |
| CA3170353A1 (en) | 2021-08-12 |
| US20210247409A1 (en) | 2021-08-12 |
| WO2021159074A1 (en) | 2021-08-12 |
| AU2021216478A1 (en) | 2022-09-08 |
| CN115917318A (zh) | 2023-04-04 |
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