JP2023513543A - 生体試料中のヘモグロビンを検出するためのグラフェンベースのセンサ - Google Patents

生体試料中のヘモグロビンを検出するためのグラフェンベースのセンサ Download PDF

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JP2023513543A
JP2023513543A JP2022548190A JP2022548190A JP2023513543A JP 2023513543 A JP2023513543 A JP 2023513543A JP 2022548190 A JP2022548190 A JP 2022548190A JP 2022548190 A JP2022548190 A JP 2022548190A JP 2023513543 A JP2023513543 A JP 2023513543A
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graphene layer
sample
hemoglobin
sensor
functionalized
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ナワナ,ナマル
アベディ,メフディ
モッラガババ,レザ
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グラフェン-ディーエックス,インコーポレイテッド
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438Electrodes
    • GPHYSICS
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • G01N33/726Devices
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • G01N33/544Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545Synthetic resin
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    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
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    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • GPHYSICS
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • GPHYSICS
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
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    • G01N33/57585Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • GPHYSICS
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
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    • B01L2200/10Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
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    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
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    • B01L2300/041Connecting closures to device or container
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    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0636Integrated biosensor, microarrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01L3/5085Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • GPHYSICS
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    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/795Porphyrin- or corrin-ring-containing peptides
    • G01N2333/805Haemoglobins; Myoglobins

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  • Health & Medical Sciences (AREA)
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JP2022548190A 2020-02-06 2021-02-08 生体試料中のヘモグロビンを検出するためのグラフェンベースのセンサ Pending JP2023513543A (ja)

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US202062970919P 2020-02-06 2020-02-06
US62/970,919 2020-02-06
PCT/US2021/017082 WO2021159074A1 (en) 2020-02-06 2021-02-08 Graphene-based sensor for detecting hemoglobin in a biological sample

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JP2023513543A true JP2023513543A (ja) 2023-03-31
JP2023513543A5 JP2023513543A5 (https=) 2024-02-14
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EP (1) EP4100739A1 (https=)
JP (1) JP2023513543A (https=)
KR (1) KR20220136407A (https=)
CN (1) CN115917318A (https=)
AU (1) AU2021216478A1 (https=)
CA (1) CA3170353A1 (https=)
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US12546746B2 (en) * 2021-05-05 2026-02-10 Ekidna Sensing Inc. Systems and devices for estimating substance concentration
US20230182133A1 (en) * 2021-12-01 2023-06-15 Graphene-Dx. Inc. Systems and methods for processing and testing biological samples
WO2025024598A1 (en) * 2023-07-24 2025-01-30 The Regents Of The University Of California Biomarker detection using graphene field effect transistor sensor arrays and multichannel data acquisition

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JP2012511156A (ja) * 2008-12-05 2012-05-17 ナノアイヴイディー,インコーポレイテッド ポイント・オブ・ケア分析器用マイクロ流体ベースのラボオンテストカード
US20120261257A1 (en) * 2011-04-18 2012-10-18 Indian Institute Of Science Low cost electrochemical disposable sensor for measuring glycated hemoglobin
US20160097764A1 (en) * 2014-10-03 2016-04-07 Rite Taste, LLC Device and method for chemical analysis
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JP2019525177A (ja) * 2016-08-11 2019-09-05 インストゥルメンテーション ラボラトリー カンパニー 自動臨床分析装置内で使用される試薬容器用の試薬組成物分注キャップ
WO2019227069A1 (en) * 2018-05-24 2019-11-28 Rite Taste, LLC A functionalized sensor for detection of biomarkers

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US20120261257A1 (en) * 2011-04-18 2012-10-18 Indian Institute Of Science Low cost electrochemical disposable sensor for measuring glycated hemoglobin
US20160097764A1 (en) * 2014-10-03 2016-04-07 Rite Taste, LLC Device and method for chemical analysis
JP2019525177A (ja) * 2016-08-11 2019-09-05 インストゥルメンテーション ラボラトリー カンパニー 自動臨床分析装置内で使用される試薬容器用の試薬組成物分注キャップ
WO2018079314A1 (ja) * 2016-10-24 2018-05-03 東レ株式会社 半導体センサおよびその製造方法、ならびに複合センサ
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EP4100739A1 (en) 2022-12-14
CA3170353A1 (en) 2021-08-12
US20210247409A1 (en) 2021-08-12
WO2021159074A1 (en) 2021-08-12
AU2021216478A1 (en) 2022-09-08
CN115917318A (zh) 2023-04-04

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