KR20220133124A - Device injecting drug provided with needle moving reciprocatively - Google Patents

Abstract

The present invention relates to a drug injection device provided with a reciprocating needle. The drug injection device comprises: a main body in which a drug is accommodated; an actuator which reciprocates with a part inserted into the main body; a movable plate which is connected to one end of the actuator located inside the main body, and is installed by being in close contact with an inner wall of the main body; a one-way valve which is connected to the movable plate; and a needle which is connected to the movable plate and penetrates the skin. According to the present invention, since the drug is injected in a process of the needle penetrating into the skin and being separated to the outside, the negative pressure generated in the skin is minimized and the drug can be smoothly discharged.

Description

DEVICE INJECTING DRUG PROVIDED WITH NEEDLE MOVING RECIPROCATIVELY

The present invention relates to a drug injection device, and more particularly, to a drug injection device having a reciprocating needle into which a drug is injected when a movable plate is retracted in a state in which the needle is penetrated into the skin.

In general, a method of penetrating a drug into the skin is used as a treatment method for skin beauty, health, obesity treatment, etc., such as wrinkles, acne removal, keratin removal, and hair loss treatment.

Examples of such a treatment method include a method of maximizing drug efficacy by making a hole in the skin and then applying a drug or cosmetic on it to allow the drug to penetrate quickly and in large amount, and stimulate the skin with a needle and the body's reflex There are methods for inducing the formation of collagen.

When a plurality of micropores are made in the skin of the human body, new flesh sprouts by the autogenous force of the damaged skin tissue, and when a therapeutic drug is applied to the area where the micropores are formed, the drug can quickly penetrate into the skin through the micropores.

In other words, due to the natural wound healing action that occurs as a number of needles penetrate the skin, the dermal tissue is newly formed and rearranged, so the scar becomes shallower, the skin is pulled tighter, fine wrinkles are reduced and the pigmentation is improved, making it healthy and clean. The skin can be revived.

In recent years, a number of drug injection devices for the skin have been supplied in order to facilitate the operation of the skin improvement method using a needle.

However, when the drug is injected at a high speed while the needle is infiltrated into the skin, a negative pressure is formed in the skin, so that the drug is not smoothly supplied, and there is a problem in that a feeling of heterogeneity is given to the affected part.

Therefore, it is possible to smoothly inject the drug in a state where negative pressure is not generated during drug injection, and research on a drug injection device having a new structure is needed to minimize the heterogeneity caused by the pressure applied during drug injection through the needle. .

Korean Patent Registration 10-1665574 (2016.10.12. Announcement) Korean Patent Publication 10-2019-0049097 (published on May 9, 2019)

An object of the present invention is to solve the above problems, so that a drug is injected in the process of detaching the needle from the skin.

The above object is connected to one end of the main body in which the drug is accommodated, the actuator reciprocating along the longitudinal direction of the main body in a state in which a portion is inserted into the inner side of the main body, the actuator located inside the main body, A movable plate installed in close contact with the inner wall of the body, a one-way valve connected to the movable plate, and a needle connected to the movable plate and penetrating the skin can be achieved by a drug injection device.

The movable plate may include at least one through hole.

In the one-way valve, when pressure is applied from the through hole, the inner circumferential surface of the one-way valve is opened away from the outer circumferential surface of the needle, and when pressure is applied from the skin side, the inner circumferential surface of the one-way valve is in close contact with the outer circumferential surface of the needle and may be closed.

It may further include an RF generator electrically connected to the needle.

The RF generator may be operated in a state in which the end of the needle penetrates the skin.

The one-way valve may include: an inner cap formed to surround an outer circumferential surface of the needle in a longitudinal direction; and at least one of an outer cap that has a larger diameter than the inner cap and is formed to surround the inner cap.

The movable plate may include at least one through hole.

In the inner cap, when pressure is applied from the through hole, the inner peripheral surface of the inner cap is opened away from the outer peripheral surface of the needle, and when pressure is applied from the skin side, the inner peripheral surface of the inner cap is in close contact with the outer peripheral surface of the needle and may be closed.

It may include one or more flow holes formed on the outer peripheral surface of the needle positioned between the inner cap and the outer cap.

an inlet connected to the inside of the main body, into which a drug is injected; And it may further include an opening and closing member for opening and closing the inlet.

The opening and closing member encloses the injection port to seal the inside of the main body, and may include a membrane through which the drug is injected through the drug injection device.

The opening/closing member may include a cap that is operably provided at the injection port to open and close.

It may further include a drug chamber connected to the inlet so that the drug is injected through the inlet.

It may further include a control valve installed in the injection port, opened when the movable plate moves in a direction approaching the skin side.

a plunger accommodated inside the main body, the actuator passes through, and is in close contact with the inner wall of the main body; and a pusher for reciprocating the plunger toward the movable plate.

a pressure sensor for measuring the inner pressure of the body; And when the pressure data measured by the pressure sensor exceeds the set pressure, it may further include a control unit for controlling the actuator to stop operating.

A guide groove for guiding the flow of the drug passing through the one-way valve from the inside of the body may be formed on the surface of the needle.

It may further include a pressure valve for adjusting the inner pressure of the main body so that the flow amount of the drug flowing through the guide groove from the inside of the main body through the one-way valve is adjusted.

According to the present invention, since the drug is administered while the needle is infiltrated into the skin and released to the outside, the negative pressure generated in the skin is minimized, so that the drug can be smoothly discharged.

In addition, when a drug is administered by penetrating the needle into the patient's skin, a separate driving energy source for the drug contained in the drug chamber is omitted by generating positive or negative pressure using a movable plate movable in a vacuum state inside the body in which the needle is installed. Even if it is, energy efficiency can be increased because it is discharged naturally.

In addition, since the drug is discharged as the needle is separated from the skin, the negative pressure generated in the skin can be minimized, thereby minimizing the feeling of heterogeneity in the skin.

1 is a cross-sectional view of a drug injection device having a reciprocating needle according to a first embodiment of the present invention.
2 and 3 show a state while moving the actuator of FIG. 1 toward the skin.
4 and 5 show a state while moving the actuator of FIG. 1 in a direction away from the skin side.
6 is a cross-sectional view of a drug injection device having a reciprocating needle according to a second embodiment of the present invention.
7 and 8 show a state while moving the actuator of FIG. 6 toward the skin.
9 and 10 show a state while moving the actuator of FIG. 6 in a direction away from the skin side.
11 is a cross-sectional view of a drug injection device having a reciprocating needle according to a third embodiment of the present invention.
12 is a cross-sectional view of a drug injection device having a reciprocating needle according to a fourth embodiment of the present invention.
13 is a cross-sectional view of a drug injection device having a reciprocating needle according to a fifth embodiment of the present invention.
14 is a cross-sectional view of a drug injection device having a reciprocating needle according to a sixth embodiment of the present invention.
15 is a cross-sectional view of a drug injection device having a reciprocating needle according to a seventh embodiment of the present invention.
16 is a cross-sectional view of a drug injection device having a reciprocating needle according to an eighth embodiment of the present invention.

Advantages and features of the present invention and methods of achieving them will become apparent with reference to the embodiments described below in detail in conjunction with the accompanying drawings. However, the present invention is not limited to the embodiments disclosed below, but may be implemented in various different forms, and only these embodiments allow the disclosure of the present invention to be complete, and those of ordinary skill in the art to which the present invention pertains. It is provided to fully inform those skilled in the art of the scope of the present invention.

The terminology used herein is for the purpose of describing the embodiments and is not intended to limit the present invention. In this specification, the singular also includes the plural, unless specifically stated otherwise in the phrase. As used herein, “comprises” and/or “comprising” does not exclude the presence or addition of one or more other components in addition to the stated components. Like reference numerals refer to like elements throughout, and "and/or" includes each and every combination of one or more of the recited elements. Although "first", "second", etc. are used to describe various elements, these elements are not limited by these terms, of course. These terms are only used to distinguish one component from another. Therefore, it goes without saying that the first component mentioned below may be the second component within the spirit of the present invention.

Unless otherwise defined, all terms (including technical and scientific terms) used herein will have the meaning commonly understood by those of ordinary skill in the art to which this invention belongs. In addition, terms defined in a commonly used dictionary are not to be interpreted ideally or excessively unless clearly specifically defined.

Prior to the description of the present invention, in various embodiments, components having the same configuration are typically described in the first embodiment using the same reference numerals, and in other embodiments, configurations different from the first embodiment are described. to explain

Hereinafter, the present invention will be described in detail with reference to the accompanying drawings.

1 is a cross-sectional view of a drug injection device having a reciprocating needle according to a first embodiment of the present invention.

Referring to Figure 1, the drug injection device having a reciprocating needle according to the first embodiment of the present invention is a body 100, an injection hole 101 formed through the outer peripheral surface of the body 100, the injection hole 101 The drug chamber 110 connected to inject the drug through, the actuator 120 reciprocating along the longitudinal direction of the main body 100 in a state in which a portion is inserted inside the main body 100, the inside of the main body 100 The movable plate 130 connected to one end of the positioned actuator 120 and installed in close contact with the inner wall surface of the main body 100 , is formed on the movable plate 130 , and is movable by the driving force of the actuator 120 . The plate 130 may include a one-way valve 140 that is opened when the plate 130 moves in a direction away from the skin, and a needle 150 that is connected to the one-way valve 140 and penetrates the skin to inject the drug.

The body 100 is to form the outer shape of the drug injection device, it may be formed in a cylindrical hollow shape.

The cross-sectional shape of the body 100 may be a hollow cylindrical shape. In the internal space of the body 100, a part of the actuator 120 is moved in a state where it is located, and the movable plate 130 is in close contact with the inner wall surface of the body 100 and can be moved along the axial direction of the actuator 120. space can be provided.

The cross-sectional shape of the body 100 may be formed in a polygonal shape other than a circular shape, but a circular shape suitable for shape processing of the movable plate 130 will be described as an example.

The injection port 101 is located on the upper left side of the main body 100 as shown in the accompanying drawings of this embodiment, but if the drug can be injected into the main body 100, any of the side wall or the upper wall surface of the main body 100 It may be formed through the wall. The drug chamber 110, which will be described later, is connected through the injection hole 101 that is formed to be penetrated in this way.

In addition, a control valve (not shown) may be installed in the inlet 101 .

The control valve may control the fluid flow by opening and closing the connection state between the drug chamber 110 and the pressure chamber (P). That is, when the control valve is opened in the process of the movable plate 130 descending, the drug L of the drug chamber 110 may be sucked by the negative pressure formed in the pressure chamber P. On the contrary, when the control valve is closed while the movable plate 130 is rising, it means to control so that a positive pressure is formed in the pressure chamber P.

Specifically, the control valve can be controlled to open so that the drug (L) of the drug chamber 110 is sucked by the negative pressure generated in the pressure chamber P while the movable plate 130 moves toward the skin (S) side. have. Conversely, the control valve may be controlled to close so that positive pressure is generated in the pressure chamber P while the movable plate 130 moves in a direction away from the skin S side. Here, the control valve may be omitted when used for a one-time use, such as when only a function of sucking and discharging a drug accommodated in the drug chamber 110 is performed.

The drug chamber 110 provided inside the drug chamber 110 contains a drug such as a liquid or gel state, or a polymer such as Sculptra in a crystalline powder form may be mixed with the drug, The drug accommodated in the drug chamber 110 is injected into the interior of the body 100 through the injection port 101 .

The drug accommodated in the interior of the drug chamber 110 generates an external force exceeding the pressure of the pressure chamber P provided inside the main body 100 to be injected into the pressure chamber P by a syringe (syringe) or an injector ( Injerctor), etc., may be used, but in this embodiment, energy efficiency is increased as well as the number of components required for implementation by allowing the pressure chamber P to be naturally sucked by the pressure change of the pressure chamber P as will be described later. to achieve a reduction effect.

That is, when the pressure chamber P is formed in a vacuum state and the pressure of the pressure chamber P is changed according to the movement of the movable plate 130 coupled to the end of the actuator 120 , the pressure chamber generated thereby The drug in the drug chamber 110 is sucked toward the pressure chamber P by the negative or positive pressure in (P), or the drug introduced into the pressure chamber P is extruded through the needle 150.

A portion of one side of the actuator 120 in the longitudinal direction may be located inside the body 100 , and a portion of the opposite side may be installed in a state exposed to the outside of the body 100 . In other words, the actuator 120 reciprocates along its axial direction by an external force, but a part of the actuator 120 is located inside the main body 100, and a part along the longitudinal direction of the actuator 120 moves in and out. This is repeated, and a portion of the opposite side may be coupled to a driving device not shown.

The driving device may be a driving device such as a solenoid valve that is fixedly coupled to the actuator 120 and can be driven to reciprocate along the longitudinal direction of the actuator 120, but the actuator 120 is a cam interlocked to reciprocate. Alternatively, since a connection structure such as gear coupling is also possible, the solenoid valve is not limited to the above-mentioned solenoid valve and may be a driving device of various types.

In the drawings attached to this embodiment, the upper surface of the movable plate 130 is coupled to the lower end of the actuator 120 so as to move integrally.

The movable plate 130 may have a predetermined thickness and may be formed to be in close contact with the inner wall surface of the body 100 . Here, when the cross-sectional shape of the body 100 is circular, the outer circumferential shape of the movable plate 130 must be circular, and when the cross-sectional shape of the body 100 is polygonal, the outer circumferential shape of the movable plate 130 must be polygonal. of course it is

The shape of the outer circumferential surface of the movable plate 130 is formed to correspond to the shape of the body 100 , and the diameter or width and length of the movable plate 130 is preferably formed to be at least equal to the inner diameter of the body 100 .

Additionally, a sealing member (not shown) may be disposed on the outer circumferential surface of the movable plate 130 . The sealing member may be made of a rubber material that is elastically deformed, and the air or fluid inside the pressure chamber P secures airtightness with the outside of the pressure chamber P due to this sealing member. It is possible to increase the efficiency of negative pressure or positive pressure.

Through-holes 131 that are radially spaced apart from the axis of movement of the actuator 120 may be formed in the movable plate 130 . A through hole 131 may be formed so that the fluid may pass in the thickness direction of the movable plate 130 . A plurality of through-holes 131 may be formed to flow toward the one-way valve 140 to be described later.

The one-way valve 140 may be formed so that air or a fluid may selectively pass in the thickness direction of the movable plate 130 .

When the one-way valve 140 is opened, the potion flowing through the through hole 131 may be configured to flow along the outer circumferential surface of the needle 150 . Here, the potion flows along the outer circumferential surface of the needle 150, but when a guide groove (not shown) is formed on the outer circumferential surface of the needle 150 from one end to the other end in the longitudinal direction, the potion flows along the guide groove. ) may be guided from one end to the other end. In this case, a guide groove passing through the arrival point of the potion sprayed from the one-way valve 140 is formed.

In addition, when there are two one-way valves 140 to be disposed, it means that two guide grooves are formed, and a number of guide grooves corresponding to the number of installed one-way valves 140 may be formed.

In the drawings attached to this embodiment, the one-way valve 140 is shown in an inclined form to have a length in the needle 150 side direction (up and down in the drawing), but this shape is only an exaggerated shape to help understanding, , may be formed in various shapes to have a shorter length according to a design value applied to the negative or positive pressure formed in the pressure chamber P. In addition, in addition to the structure of the one-way valve 140 shown, any structure such as a valve structure capable of performing a function of guiding a fluid consisting of a liquid or a gas to flow in only one direction in the pressure chamber P may be applied.

The one-way valve 140 may be formed of a thin rubber material, preferably silicone rubber. Since the silicone rubber has excellent elasticity and low thermal conductivity, when a function such as a laser or RF radio frequency is additionally applied as described below, it effectively shields heat generated by laser irradiation, etc. It has the advantage of preventing deterioration and damage.

In addition, as the material of the one-way valve 140 , any material having elasticity and liquid impermeability according to selection such as nitrile butadiene rubber (NBR) may be used.

The one-way valve 140 is opened while the inner peripheral surface of the one-way valve 140 is away from the outer peripheral surface of the needle 150 when pressure is applied from the through-hole 131, and when pressure is applied from the skin (S) side, the one-way valve The inner circumferential surface of 140 may be formed in a shape that is easy to adhere to the outer circumferential surface of the needle 150 . In this case, the end of the one-way valve 140 in contact with the outer circumferential surface of the needle 150 is preferably curved convexly toward the needle 150 .

The needle 150 allows the drug (L) passing through the one-way valve 140 to flow along the inner space, and then to be injected toward the skin (S) along the outer circumferential surface of the needle 150.

A plurality of needles 150 may be radially arranged around the axis of movement of the actuator 120 . However, in this embodiment, as shown in the accompanying drawings for convenience of description, it is assumed that one or two needles 150 are provided in the cross-sectional view.

In addition, when an RF generator (not shown) electrically connected to the needle 150 is further included, the needle 150 is in a state in which an environment in which electricity does not flow inside the drug is implemented by applying an insulation coating to the needle. It may be configured so that electric energy generated from the RF generator in a state that penetrates into the skin (S) can be supplied into the skin through the needle (150).

Hereinafter, an operation process of the drug injection device having a reciprocating needle according to the first embodiment of the present invention will be described.

2 and 3 show a state while moving the actuator of FIG. 1 toward the skin.

First, referring to FIG. 2 , when a driving force toward the skin side is applied to the actuator 120 , the actuator 120 moves downward in the drawing.

As the outer peripheral surface of the movable plate 130 moved integrally with the actuator 120 descends in close contact with the inner wall surface of the body 100 , a negative pressure is generated in the pressure chamber P.

At this time, when the inlet 101 is opened, or when a control valve is installed to control the opening of the inlet 101, the drug contained in the drug chamber 110 is sucked into the pressure chamber P.

The drug introduced into the pressure chamber (P) in the process of continuously descending the movable plate 130 is maintained in a vacuum state by the one-way valve 140, so that the state in which the drug is temporarily accommodated on the movable plate 130 is maintained. can be

At the same time, in order to prevent negative pressure from being formed in the space between the skin (S) and the movable plate 130 , the air is discharged through the vent hole 102 formed through the outer wall of the body 100 .

Here, most of the internal pressure existing in the space is discharged through the vent 102 by the one-way valve 140 maintaining a closed state.

Referring to FIG. 3, FIG. 3 is a state in which the movable plate 130 of the state shown in FIG. 2 is further lowered, and a larger amount of the drug (L) is temporarily accommodated on the movable plate 130, and is movable. It is located at H2, which is the maximum descending height of the plate 130 .

At this time, when the position of the vent 102 is defined as the maximum moving distance from H1, which is the initial position of the movable plate 130, to H2, the distance between H1 and H2 is 2-3 mm as the movable plate 130 is shown as an example. may be, and the movable plate 130 may be set to a position passing through H2. This is because, if the position of the vent 102 is the position of H1-H2, the drug (L) temporarily accommodated in the movable plate 130 may leak to the outside.

4 and 5 show a state while moving the actuator of FIG. 1 in a direction away from the skin side.

First, referring to FIG. 4 , the needle 150 starts to rise by the upward driving force applied to the actuator 120 in the state that it penetrates the skin S.

As the movable plate 130 starts to rise, a positive pressure is generated in the pressure chamber P, whereby the drug L temporarily accommodated on the movable plate 130 is discharged through the through hole 131 . At this time, a flow path F may be defined between the inner circumferential surface of the one-way valve 140 and the outer circumferential surface of the needle 150 . In addition, a gap C is formed between the inner circumferential surface of the one-way valve 140 and the outer circumferential surface of the needle 150 by the positive pressure acting to push the one-way valve 140 . The drug (L) injected from the one-way valve 140 passes through the flow path (F) and the drug (L) passes through the gap (C), and is introduced along the outer peripheral surface of the needle 150 .

The drug (L) accommodated in the movable plate 130 at the same time as the movable plate 130 gradually rises gradually flows along the outer circumferential surface of the needle 150, and is formed by being invaded by the end of the needle 150 Drug supply proceeds through the process of being discharged into the skin (S) through the hole.

At this time, since the drug supply that can offset the negative pressure inside the skin (S) generated as the needle 150 that has penetrated into the skin (S) escapes is made at the same time, the drug (L) is smoothly supplied and at the same time to the affected area The effect of minimizing heterogeneity can be expected. As shown in Figure 5, when the cut portion 520 of the needle 150 is completely separated from the skin (S), the drug (L) is completely discharged by the positive pressure inside the pressure chamber (P) in the same manner as described above. Thus, there is no residual drug on the movable plate 130 .

6 is a cross-sectional view of a drug injection device having a reciprocating needle according to a second embodiment of the present invention.

Referring to Figure 6, the drug injection device having a reciprocating needle according to the second embodiment of the present invention is a main body 200, an injection hole 201 formed through the outer peripheral surface of the main body 200, the injection hole 201 The drug chamber 210 connected to inject the drug through, the actuator 220 reciprocating along the longitudinal direction of the main body 200 with a part inserted inside the main body 200, the inside of the main body 200 The movable plate 230 coupled to one end of the positioned actuator 220 and installed in close contact with the inner wall surface of the main body 200, is formed on the movable plate 230, and is movable by the driving force of the actuator 220 The plate 230 may include a one-way valve 240 that is opened when the plate 230 moves in a direction away from the skin, and a needle 250 that is connected to the one-way valve 240 and penetrates the skin to inject the drug.

In the drug injection device having a reciprocating needle according to the second embodiment of the present invention, as compared with the first embodiment, the one-way valve 140 of the first embodiment has an inner cap ( 410) and the outer cap 420, there is a difference in that a plurality of flow holes 251 are additionally formed in the needle 150 of the first embodiment.

In this embodiment, the one-way valve 240 may be formed so that air or fluid can selectively pass in the thickness direction of the movable plate 230 . That is, the one-way valve 240 is opened when pressure is applied from the through-hole 231 , and when pressure is applied from the skin (S) side, it can be formed in a shape that is easy to adhere to the outer circumferential surface of the needle 250 .

In this case, the through hole 231 may be formed at a position where the fluid inside the pressure chamber P can be guided between the inner circumferential surface of the inner cap 410 and the outer circumferential surface of the needle 150 .

The one-way valve 240 has a larger diameter than the inner cap 241 and the inner cap 241 that are formed to surround the outer circumferential surface along the longitudinal direction of the needle 250 and are spaced apart from the outer side of the inner cap 241 to wrap. It may include an outer cap 242 formed.

The inner cap 241 may be formed in a hollow conical shape in which one end having a relatively small diameter is in close contact with the outer circumferential surface of the needle 250 . At this time, the outer cap 242 is formed in a hollow conical shape having a larger diameter than the inner cap 241 and is disposed to surround the inner cap 241 radially outwardly, thereby forming the outer circumferential surface of the inner cap 241 and the outer cap. A flow path F may be defined between the inner peripheral surfaces of 242 .

The inner cap 241 and the outer cap 242 are thin films having elastic restoring force, and may form a boundary between the pressure between the pressure chamber P and the drug chamber 210 .

In particular, the inner cap 241 and the outer cap 242 may be formed of a thin rubber material, preferably silicone rubber. Since the silicone rubber has excellent elasticity as well as low thermal conductivity, when a function such as a laser or RF high frequency is additionally applied as described below, it effectively shields heat generated by laser irradiation, etc. It has the advantage of preventing drug deterioration and damage.

In addition, as a material of the inner cap 241 and the outer cap 242 , any material having elasticity and liquid impermeability according to selection of nitrile butadiene rubber (NBR) may be used.

When pressure is applied from the through-hole 231, the inner cap 241 of the inner cap 241 is opened away from the outer circumferential surface of the needle 250, and when pressure is applied from the skin (S) side, the needle ( 250) may be formed in a shape that is easy to adhere to the outer circumferential surface. In this case, the end of the inner cap 241 in contact with the outer circumferential surface of the needle 250 is preferably curved convexly toward the needle 250 .

After the drug (L) passing through the one-way valve 240 flows along the inner space, the needle 250 is discharged into the skin (S) through the cut portion 252 formed at the end of the needle 250 so that it can be discharged into the skin (S). do.

A plurality of needles 250 may be radially arranged around the axis of movement of the actuator 220 . However, in this embodiment, for convenience of description, it is assumed that one or two needles 250 are provided as shown in the accompanying drawings.

In addition, the needle 250 may include a plurality of flow holes 251 . The flow hole 251 may be formed on the outer peripheral surface of the needle 250 exposed between the inner cap 241 and the outer cap 242 .

The flow hole 251 has a function of guiding that, when the inner cap 241 is opened and the drug L is introduced, the introduced drug L is introduced into the inner space of the needle 250 through the flow hole 251 . will perform

In addition, the skin-side end of the needle 250 is formed with a cut portion 252 processed to form a sharp shape, if necessary, to facilitate penetration while in contact with the patient's skin.

After the inner cap 241 of the one-way valve 240 is opened and the drug (L) is introduced, the introduced drug (L) passes through the inner space of the needle 250 and is guided along its longitudinal direction, the needle ( By being discharged from the cut part 252 of the 250), the drug (L) is injected into the skin (S).

In addition, when an RF generator (not shown) electrically connected to the needle 250 is further included, an environment in which electricity does not flow inside the drug is implemented by applying an insulation coating to the needle, the needle 250 In a state in which the cut portion 252 penetrates the skin S, the electrical energy generated from the RF generator may be configured to be supplied into the skin through the needle 250 .

Hereinafter, an operating process of the drug injection device having a reciprocating needle according to an embodiment of the present invention will be described.

7 and 8 show a state while moving the actuator of FIG. 6 toward the skin.

First, referring to FIG. 7 , when a driving force toward the skin side is applied to the actuator 220 , the actuator 220 is moved downward in the drawing.

As the outer circumferential surface of the movable plate 230 moved integrally with the actuator 220 descends in close contact with the inner wall surface of the body 200 , a negative pressure is generated in the pressure chamber P.

At this time, when the injection port 201 is opened, or when a control valve is installed to control the opening of the injection port 201 , the drug contained in the drug chamber 210 is sucked into the pressure chamber P.

The drug introduced into the pressure chamber P while the movable plate 230 continuously descends is maintained in a vacuum state by the inner cap 241 of the one-way valve 240, so that the drug is temporarily placed on the movable plate 230. Acceptable status can be maintained.

At the same time, in order to prevent negative pressure from being formed in the space between the skin S and the movable plate 230 , the air is discharged through the vent 202 formed through the outer wall of the body 200 .

Here, some of the pressure may be transmitted through the flow hole 251 of the needle 250, but most of the air present in the space by the inner cap 241 that maintains a closed state is ventilated 202 ) is released through

Referring to FIG. 8, FIG. 3 is a state in which the movable plate 230 of the state shown in FIG. 2 is further lowered, and a larger amount of the drug (L) is temporarily accommodated on the movable plate 230, and the movable plate 230 is moved. It is located at H2, which is the maximum descending height of the plate 230 .

At this time, when the position of the vent 202 is defined as the maximum movement distance from H1, which is the initial position of the movable plate 230, to H2 as shown in the movable plate 230 as an example, the distance between H1 and H2 is 2-3 mm may be, and the movable plate 230 may be set to a position passing through H2. This is because, if the position of the vent 202 is the position of H1-H2, the drug (L) temporarily accommodated in the movable plate 230 may leak to the outside.

9 and 10 show a state while moving the actuator of FIG. 6 in a direction away from the skin side.

First, referring to FIG. 9 , the cut part 252 of the needle 250 starts to rise by the upward driving force applied to the actuator 220 in the state that it penetrates into the skin (S).

As the movable plate 230 starts to rise, a positive pressure is generated in the pressure chamber P, whereby the drug L temporarily accommodated on the movable plate 230 is discharged through the through hole 231 . At this time, in the process of flowing the flow path F formed between the inner cap 241 and the outer cap 242, a pressure to push the inner cap 241 by the positive pressure acts on the inner circumferential surface of the inner cap 241 and A gap (C) is formed between the outer peripheral surface of the needle (250). The drug (L) passes through the gap (C), and is introduced into the flow hole (251) of the needle (250).

As the movable plate 230 gradually rises, the drug (L) accommodated in the movable plate 230 gradually flows through the needle 250, and cuts the cut 252 formed at the end of the needle 250. The drug supply proceeds through the process of being discharged into the skin (S).

At this time, since the drug supply that can offset the negative pressure inside the skin (S) generated as the needle 250 that has penetrated into the skin (S) escapes is made at the same time, the drug (L) is supplied smoothly and at the same time to the affected area The effect of minimizing heterogeneity can be expected.

As shown in Figure 10, when the cut 252 of the needle 250 is completely separated from the skin (S), the drug (L) is completely discharged by the positive pressure inside the pressure chamber (P) in the same manner as described above. Thus, there is no residual drug on the movable plate 230 .

11 is a cross-sectional view of a drug injection device having a reciprocating needle according to a third embodiment of the present invention.

11, the drug injection device having a reciprocating needle according to the third embodiment of the present invention, unlike the first embodiment, the movable plate 130' has a certain curvature toward the needle 150. and may have a curved shape.

In other words, the movable plate 130 ′ may have an arc-shaped cross-sectional shape in which the center adjacent to the needle 150 protrudes toward the needle 150 .

Therefore, in this embodiment, the drug accumulated on the circumferential surface of the movable plate 130' is collected in the center of the movable plate 130' along the arc-shaped surface of the movable plate 130', and then the through hole 131 and Through the one-way valve 140, it may be supplied to the skin (S).

As a result, it is possible to prevent the drug accumulated on the circumferential surface of the movable plate 130' from being lost and to improve the drug delivery efficiency.

On the other hand, the movable plate 130' of this embodiment has a certain curvature toward the needle 150, and the curved shape is applicable to other embodiments, and the present invention is not particularly limited thereto.

12 is a cross-sectional view of a drug injection device having a reciprocating needle according to a fourth embodiment of the present invention.

As shown in Figure 12, the drug injection device having a reciprocating needle according to the fourth embodiment of the present invention, unlike the first embodiment, the drug chamber 110 is omitted, opening and closing the injection port (101) It may further include an opening/closing member and a vent valve 104 for opening and closing the vent 102 .

In this embodiment, the opening/closing member surrounds the injection port 101 to seal the inside of the main body 100, and may be a membrane 103 through which the drug injection device is penetrated and the drug is injected. Therefore, in this embodiment, the drug injection device may be penetrated through the membrane 103 to inject the drug into the inner side of the main body 100 (ie, the pressure chamber P), where the drug injection device is not particularly limited. However, it may be a syringe in which the drug is stored.

The membrane 103 may include an elastic material, and a portion of the membrane 103 that is penetrated and opened by the drug injection device may be closed again by the elastic force.

In this embodiment, the vent valve 104 closes the vent 102 when the movable plate 130 is stopped, thereby preventing foreign substances from entering the space between the skin S and the movable plate 130 and , When the movable plate 130 is moved, the vent 102 is opened, and external air is sucked through the vent 102 or the space between the movable plate 130 and the skin S through the vent 102 . of air can be exhausted.

On the other hand, the vent valve 104 of this embodiment can be applied to other embodiments, and the present invention is not particularly limited thereto.

13 is a cross-sectional view of a drug injection device having a reciprocating needle according to a fifth embodiment of the present invention.

As shown in FIG. 13 , in the drug injection device having a reciprocating needle according to the fifth embodiment of the present invention, the membrane 103 may be replaced with the cap 105 , unlike the fourth embodiment.

In this embodiment, the cap 105 may be provided so as to be able to open and close the injection hole (101). This cap 105 may be screwed to the injection hole 101 . Therefore, after opening the cap 105 in this embodiment. By inserting the drug injection device into the cap 105, it is possible to inject the drug into the inner side of the body 100 (ie, the pressure chamber P),

14 is a cross-sectional view of a drug injection device having a reciprocating needle according to a sixth embodiment of the present invention.'

14, the drug injection device having a reciprocating needle according to the sixth embodiment of the present invention, unlike the first embodiment, has a plunger 160, a pusher 170, a pressure sensor 600 and A control unit 700 may be further included.

The plunger 160 is accommodated in the inner side of the body 100 (ie, the pressure chamber P), the actuator 120 penetrates, and may be in close contact with the inner wall of the body 100 . The plunger 160 may include an elastic material, and may reciprocate toward the movable plate 130 , and push the drug contained in the pressure chamber P to the through hole 131 .

Here, according to the distance that the plunger 160 moves toward the movable plate 130, the amount of the drug accommodated in the pressure chamber P being pushed into the through hole 131 may be adjusted, and through this, the pressure chamber ( It is possible to control the amount of drug accommodated in P) delivered to the skin (S).

Furthermore, when the pressure chamber (P) is in a vacuum state, when the plunger 160 moves toward the movable plate 130 frame, the plunger 160 even in a non-contact state with the drug contained in the pressure chamber P, the plunger 160 ) and due to the pneumatic pressure between the drug, the drug accommodated in the pressure chamber (P) can be pushed to the through hole (131). Here, the plunger 160 may be controlled by the pusher 170 to move toward the movable plate 130 after the needle 150 invaded into the skin S is discharged.

In addition, when the pressure chamber (P) is in a non-vacuum state, when the plunger 160 moves toward the movable plate 130, the plunger 160 is in contact with the drug contained in the pressure chamber P, the pressure chamber The drug accommodated in (P) may be pushed into the through hole 131 . Here, the plunger 160 may be controlled by the pusher 170 to move toward the movable plate 130 after the needle 150 invaded into the skin S is discharged.

The pusher 170 may reciprocate the plunger 160 toward the movable plate 130 . For example, the lower end of the pusher 170 may be coupled to the plunger 160 , and the upper end of the pusher 170 may protrude to the outside of the body 100 . The pusher 170 may be automatically reciprocated by a separate driving device, or may be manually reciprocated by a user. However, when the pusher 170 is automatically reciprocated, the reciprocating movement of the pusher 170 may be controlled by the controller 700 .

The pressure sensor 600 serves to measure the inner pressure of the body 100, that is, the pressure of the pressure chamber (P). This pressure sensor 600 may be installed in the pressure chamber (P).

The controller 700 may control the actuator 120 to stop operating when the pressure data measured by the pressure sensor 600 exceeds a set pressure.

As such, when the pressure data measured by the pressure sensor 600 exceeds the set pressure, the through-hole 131 or the one-way valve 140 may be blocked. In this case, it is impossible to release the blockage of the through hole 131 or the one-way valve 140 due to the positive pressure generated in the pressure chamber P by the rise of the movable plate 130 . Accordingly, the controller 700 may control the actuator 120 to stop operating when the pressure data measured by the pressure sensor 600 exceeds the set pressure.

Furthermore, the control unit 700 controls the pusher 170 so that the plunger 160 moves toward the movable plate 130, so that the plunger 160 is positive pressure applied toward the through hole 131 or the one-way valve 140. Thus, the blockage of the through hole 131 or the one-way valve 140 may be released.

15, the drug injection device having a reciprocating needle according to the seventh embodiment of the present invention is different from the second embodiment, the plunger 260, the pusher 270, the pressure sensor 600 and A control unit 700 may be further included.

The plunger 260 may be accommodated in the inner side (ie, the pressure chamber P) of the main body 200 , the actuator 220 may pass through, and may be in close contact with the inner wall of the main body 200 . The plunger 260 may include an elastic material, reciprocate with respect to the movable plate 230 , and push the drug contained in the pressure chamber P to the through hole 231 .

Here, according to the distance that the plunger 260 moves toward the movable plate 230, the amount of the drug accommodated in the pressure chamber P being pushed into the through hole 231 may be adjusted, and through this, the pressure chamber ( It is possible to control the amount of drug accommodated in P) delivered to the skin (S).

Furthermore, when the pressure chamber (P) is in a vacuum state, when the plunger 260 moves toward the movable plate 230 frame, the plunger 260 even in a non-contact state with the drug contained in the pressure chamber P, the plunger 260 ) and due to the pneumatic pressure between the drug, the drug accommodated in the pressure chamber (P) can be pushed to the through hole (131). Here, the plunger 260 may be controlled by the pusher 270 to move toward the movable plate 230 after the needle 250 is invaded into the skin S.

In addition, when the pressure chamber (P) is in a non-vacuum state, when the plunger 260 moves toward the movable plate 230, the plunger 260 is in contact with the drug contained in the pressure chamber P, the pressure chamber The drug accommodated in (P) may be pushed into the through hole 231 . Here, the plunger 260 may be controlled by the pusher 270 to move toward the movable plate 230 after the needle 150 is invaded into the skin S.

The pusher 270 may reciprocate the plunger 260 with respect to the movable plate 230 . For example, the lower end of the pusher 270 may be coupled to the plunger 260 , and the upper end of the pusher 270 may protrude to the outside of the body 200 . The pusher 270 may be automatically reciprocated by a separate driving device, or may be manually reciprocated by a user. However, when the pusher 270 is automatically reciprocated, the reciprocating movement of the pusher 270 may be controlled by the controller 700 .

The pressure sensor 600 serves to measure the inner pressure of the body 100, that is, the pressure of the pressure chamber (P). This pressure sensor 600 may be installed in the pressure chamber (P).

The controller 700 may control the actuator 120 to stop operating when the pressure data measured by the pressure sensor 600 exceeds a set pressure.

As such, when the pressure data measured by the pressure sensor 600 exceeds the set pressure, the through-hole 131 or the one-way valve 140 may be blocked. In this case, it is impossible to release the blockage of the through hole 131 or the one-way valve 140 due to the positive pressure generated in the pressure chamber P by the rise of the movable plate 130 . Accordingly, the controller 700 may control the actuator 120 to stop operating when the pressure data measured by the pressure sensor 600 exceeds the set pressure.

Furthermore, the control unit 700 controls the pusher 170 so that the plunger 160 moves toward the movable plate 130, so that the plunger 160 is positive pressure applied toward the through hole 131 or the one-way valve 140. Thus, the blockage of the through hole 131 or the one-way valve 140 may be released.

16 is a cross-sectional view of a drug injection device having a reciprocating needle according to an eighth embodiment of the present invention.

As shown in Figure 16, the drug injection device having a reciprocating needle according to the eighth embodiment of the present invention, unlike the first embodiment, a guide groove 151 is formed on the surface of the needle 150, It may further include a pressure valve 190 for adjusting the pressure inside the body 100 (ie, the pressure chamber (P)).

In this embodiment, a guide groove 151 for guiding the flow of the drug passing through the one-way valve 140 from the inside of the body 100 may be formed on the surface of the needle 150 . For example, the guide groove 151 may have a spiral shape or a line shape, and as long as it has a shape capable of guiding the flow of the drug, various shapes may be applied. The pressure valve 190 is the body 100 . It is possible to adjust the pressure inside the body 100 (ie, the pressure chamber (P)) so that the flow amount of the drug flowing from the inside of the one-way valve 140 through the guide groove 151 is adjusted. The pressure valve 190 is provided in the air outlet 180 connected to the pressure chamber P of the body 100 to open and close the air outlet 180 , and according to the adjustment of the opening degree of the pressure valve 190 , the pressure The pressure of the chamber P may be adjusted. The adjustment of the opening degree of the pressure valve 190 may be controlled by the controller 700 .

In this embodiment, positive pressure is generated in the pressure chamber (P) by the lifting and lowering of the movable plate 130, and the drug accommodated in the pressure chamber (P) passes through the one-way valve 140 and flows through the guide groove 151 and the skin When delivered to (S), by adjusting the pressure of the pressure chamber (P) by adjusting the opening degree of the pressure chamber (P), from the inside of the main body 100 through the one-way valve 140 through the guide groove (151) It is possible to control the flow amount of the flowing drug.

The guide groove 151 and the pressure valve 190 of this embodiment can be applied to other embodiments, and the present invention is not particularly limited thereto.

Therefore, according to the present invention, since the drug is administered while the needle is infiltrated into the skin and escaped to the outside, the negative pressure generated in the skin is minimized, so that the drug can be smoothly discharged.

In addition, when a drug is administered by penetrating the needle into the patient's skin, a separate driving energy source for the drug contained in the drug chamber is omitted by generating positive or negative pressure using a movable plate movable in a vacuum state inside the body in which the needle is installed. Even if it is, energy efficiency can be increased because it is discharged naturally.

In addition, since the drug is discharged as the needle is separated from the skin, the negative pressure generated in the skin can be minimized, thereby minimizing the feeling of heterogeneity in the skin.

As mentioned above, although embodiments of the present invention have been described with reference to the accompanying drawings, those skilled in the art to which the present invention pertains know that the present invention can be embodied in other specific forms without changing its technical spirit or essential features. you will be able to understand Therefore, it should be understood that the embodiments described above are illustrative in all respects and not restrictive.

100: body
101: inlet
110: drug chamber
120: actuator
130: movable plate
140: one-way valve
150: needle

Claims (18)

The body in which the drug is accommodated on the inside;
an actuator that reciprocates in a state in which a portion is inserted into the body;
a movable plate connected to one end of an actuator positioned inside the main body and installed in close contact with the inner wall of the main body;
a one-way valve connected to the movable plate; and
A drug injection device having a needle that reciprocates, which is connected to the movable plate and includes a needle penetrating the skin. According to claim 1,
The movable plate is
A drug injection device having a reciprocating needle comprising at least one through-hole. 3. The method of claim 2,
The one-way valve is
When pressure is applied from the through hole, the inner circumferential surface of the one-way valve is opened away from the outer circumferential surface of the needle,
When pressure is applied from the skin side, the drug injection device having a reciprocating needle, characterized in that the inner peripheral surface of the one-way valve is closed in close contact with the outer peripheral surface of the needle. 4. The method of claim 3,
A drug injection device having a reciprocating needle, further comprising an RF generator electrically connected to the needle. 5. The method of claim 4,
A drug injection device having a reciprocating needle, wherein the RF generator is operated while the end of the needle is penetrated into the skin. According to claim 1,
The one-way valve is
an inner cap formed to surround an outer circumferential surface of the needle in the longitudinal direction; and
A drug injection device having a reciprocating needle, comprising at least one of an outer cap having a larger diameter than the inner cap and formed to surround it. 7. The method of claim 6,
The movable plate,
A drug injection device having a reciprocating needle comprising at least one through-hole. 7. The method of claim 6,
The inner cap,
When pressure is applied from the through hole, the inner circumferential surface of the inner cap is opened away from the outer circumferential surface of the needle,
When pressure is applied from the skin side, the inner peripheral surface of the inner cap is closed in close contact with the outer peripheral surface of the needle, a drug injection device having a reciprocating needle. 7. The method of claim 6,
A drug injection device having a needle reciprocating, comprising one or more flow holes formed on the outer peripheral surface of the needle positioned between the inner cap and the outer cap. According to claim 1,
an inlet connected to the inside of the main body, into which a drug is injected; and
A drug injection device having a needle reciprocating, further comprising an opening and closing member for opening and closing the injection port. 11. The method of claim 10,
The opening and closing member surrounds the injection port to seal the inside of the main body, the drug injection device having a reciprocating needle, including a membrane through which the drug is injected by the drug injection device. 11. The method of claim 10,
The opening and closing member is a drug injection device having a needle reciprocating, including a cap that is provided to be opened and closed at the injection port. 11. The method of claim 10,
A drug injection device having a reciprocating needle, further comprising a drug chamber connected to the inlet so that the drug is injected through the inlet. According to claim 1,
A drug injection device having a reciprocating needle, which is installed in the injection port and further includes a control valve that is opened when the movable plate moves in a direction close to the skin side. According to claim 1,
a plunger accommodated in the body and in close contact with the inner wall of the body; and
A drug injection device having a reciprocating needle, further comprising a pusher for reciprocating the plunger with respect to the movable plate. According to claim 1,
a pressure sensor for measuring the inner pressure of the body; and
When the pressure data measured by the pressure sensor exceeds the set pressure, the actuator further comprising a control unit for controlling the operation to stop, the drug injection device having a reciprocating needle. According to claim 1,
A drug injection device having a needle reciprocating, in which a guide groove is formed on the surface of the needle to guide the flow of the drug through the one-way valve from the inside of the main body. According to claim 1,
Drug injection device having a needle reciprocating from the inside of the body through the one-way valve, further comprising a pressure valve for adjusting the inner pressure of the body so that the flow amount of the drug flowing through the guide groove is adjusted.

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