KR20220038068A - Cd3 항원 결합 단편 및 이를 포함하는 조성물 - Google Patents

Cd3 항원 결합 단편 및 이를 포함하는 조성물 Download PDF

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KR20220038068A
KR20220038068A KR1020227002573A KR20227002573A KR20220038068A KR 20220038068 A KR20220038068 A KR 20220038068A KR 1020227002573 A KR1020227002573 A KR 1020227002573A KR 20227002573 A KR20227002573 A KR 20227002573A KR 20220038068 A KR20220038068 A KR 20220038068A
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seq
amino acid
antigen
acid sequence
receptor
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볼커 쉘렌버거
필리페 쿤
안드레 프렌젤
다라흐 맥칸
제임스 맥로이
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아뮤닉스 파마슈티컬스, 인크.
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • A61K40/4204—Epidermal growth factor receptors [EGFR]
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    • C07K14/475—Growth factors; Growth regulators
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    • C12N15/09—Recombinant DNA-technology
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    • A61K2239/59—Reproductive system, e.g. uterus, ovaries, cervix or testes
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
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KR1020227002573A 2019-06-26 2020-06-25 Cd3 항원 결합 단편 및 이를 포함하는 조성물 Pending KR20220038068A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962866746P 2019-06-26 2019-06-26
US62/866,746 2019-06-26
US202063041059P 2020-06-18 2020-06-18
US63/041,059 2020-06-18
PCT/US2020/039673 WO2020264200A1 (en) 2019-06-26 2020-06-25 Cd3 antigen binding fragments and compositions comprising same

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KR20220038068A true KR20220038068A (ko) 2022-03-25

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US (2) US20230121775A1 (https=)
EP (1) EP3990497A4 (https=)
JP (2) JP7651481B2 (https=)
KR (1) KR20220038068A (https=)
CN (1) CN115175933A (https=)
AU (1) AU2020308868A1 (https=)
BR (1) BR112021026089A2 (https=)
CA (1) CA3143519A1 (https=)
CL (1) CL2021003448A1 (https=)
CO (1) CO2022000406A2 (https=)
CR (1) CR20210628A (https=)
DO (1) DOP2021000264A (https=)
EC (1) ECSP22005986A (https=)
IL (1) IL289102A (https=)
MX (1) MX2021015880A (https=)
PE (1) PE20220600A1 (https=)
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WO2025220804A1 (ko) * 2024-04-18 2025-10-23 주식회사 큐로셀 Cd5에 대한 신규 항체 및 이의 용도

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WO2020160156A2 (en) 2019-01-30 2020-08-06 Immutics, Inc. Anti-gal3 antibodies and uses thereof
CA3143519A1 (en) * 2019-06-26 2020-12-30 Volker Schellenberger Cd3 antigen binding fragments and compositions comprising same
MX2023013382A (es) 2020-04-04 2024-01-30 Janux Therapeutics Inc Composiciones y metodos relacionados con anticuerpos activados contra tumores dirigidos a egfr y antigenos de celulas efectoras.
EP4157338A4 (en) 2020-05-26 2024-11-13 TrueBinding, Inc. METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING
KR20230041711A (ko) 2020-06-25 2023-03-24 아뮤닉스 파마슈티컬스, 인크. Her-2 표적화 이중특이적 조성물 및 이의 제조 및 사용 방법
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WO2022040444A1 (en) * 2020-08-20 2022-02-24 A2 Biotherapeutics, Inc. Compositions and methods for treating egfr positive cancers
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WO2022170619A1 (en) * 2021-02-11 2022-08-18 Adagene Pte. Ltd. Anti-cd3 antibodies and methods of use thereof
US20240254241A1 (en) * 2021-05-11 2024-08-01 Janux Therapeutics, Inc. Antibodies targeting egfr and cd3 and uses thereof
WO2023092099A1 (en) * 2021-11-19 2023-05-25 Ardeagen Corporation Gpc3 binding agents, conjugates thereof and methods of using the same
WO2023192973A1 (en) * 2022-04-01 2023-10-05 Cytomx Therapeutics, Inc. Activatable multispecific molecules and methods of use thereof
CN116063498A (zh) * 2022-04-27 2023-05-05 博际生物医药科技(杭州)有限公司 单域抗Nectin-4抗体
KR20250133776A (ko) 2023-02-10 2025-09-08 아뮤닉스 파마슈티컬스, 인크. 전립선-특이적 막 항원(psma)을 표적화하는 조성물 및 이의 제조 방법 및 사용 방법
CN121949565A (zh) 2023-04-17 2026-05-01 阿穆尼克斯制药公司 靶向表皮生长因子受体的组合物及其制备和使用方法
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CN120230203A (zh) * 2023-12-28 2025-07-01 四川思柏沃生物技术有限公司 抗cd3抗体及其用途
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CA3143519A1 (en) * 2019-06-26 2020-12-30 Volker Schellenberger Cd3 antigen binding fragments and compositions comprising same
JP7725466B2 (ja) * 2019-11-13 2025-08-19 アムニクス ファーマシューティカルズ， インコーポレイテッド バーコード化されたｘｔｅｎポリペプチドおよびその組成物、ならびにその作製および使用方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025220804A1 (ko) * 2024-04-18 2025-10-23 주식회사 큐로셀 Cd5에 대한 신규 항체 및 이의 용도

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CN115175933A (zh) 2022-10-11
JP2025106277A (ja) 2025-07-15
EP3990497A4 (en) 2023-07-19
WO2020264200A1 (en) 2020-12-30
JP2022537824A (ja) 2022-08-30
US20230121775A1 (en) 2023-04-20
BR112021026089A2 (pt) 2022-03-22
IL289102A (en) 2022-02-01
AU2020308868A1 (en) 2022-01-20
CR20210628A (es) 2022-03-22
US20210054077A1 (en) 2021-02-25
EP3990497A1 (en) 2022-05-04
MX2021015880A (es) 2022-03-22
ECSP22005986A (es) 2022-04-29
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