KR20210142665A - 세포 사멸에 대한 증가된 내성을 갖는 변형된 면역 효과기 세포 - Google Patents

세포 사멸에 대한 증가된 내성을 갖는 변형된 면역 효과기 세포 Download PDF

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KR20210142665A
KR20210142665A KR1020217032464A KR20217032464A KR20210142665A KR 20210142665 A KR20210142665 A KR 20210142665A KR 1020217032464 A KR1020217032464 A KR 1020217032464A KR 20217032464 A KR20217032464 A KR 20217032464A KR 20210142665 A KR20210142665 A KR 20210142665A
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immune effector
cells
effector cell
trail
cell
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Korean (ko)
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마이클 에이먼 피터 오드와이어
수브하쉬스 사카르
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오엔케이 테라퓨틱스 리미티드
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Priority claimed from EP19164241.2A external-priority patent/EP3712257A1/en
Priority claimed from GBGB1917588.4A external-priority patent/GB201917588D0/en
Priority claimed from GBGB2001593.9A external-priority patent/GB202001593D0/en
Application filed by 오엔케이 테라퓨틱스 리미티드 filed Critical 오엔케이 테라퓨틱스 리미티드
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    • C12N5/0646—Natural killers cells [NK], NKT cells
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KR1020217032464A 2019-03-21 2020-03-20 세포 사멸에 대한 증가된 내성을 갖는 변형된 면역 효과기 세포 Ceased KR20210142665A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP19164241.2 2019-03-21
EP19164241.2A EP3712257A1 (en) 2019-03-21 2019-03-21 Modified natural killer cells with increased resistance to cell death
GBGB1917588.4A GB201917588D0 (en) 2019-12-02 2019-12-02 modified immune effector cells with increased resistance to cell death
GB1917588.4 2019-12-02
GB2001593.9 2020-02-06
GBGB2001593.9A GB202001593D0 (en) 2020-02-06 2020-02-06 Modified Immune effector cells with increased resistance to cell death
PCT/EP2020/057879 WO2020188105A1 (en) 2019-03-21 2020-03-20 Modified immune effector cells with increased resistance to cell death

Publications (1)

Publication Number Publication Date
KR20210142665A true KR20210142665A (ko) 2021-11-25

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KR1020217032464A Ceased KR20210142665A (ko) 2019-03-21 2020-03-20 세포 사멸에 대한 증가된 내성을 갖는 변형된 면역 효과기 세포

Country Status (10)

Country Link
US (1) US20220143089A1 (https=)
EP (1) EP3942022A1 (https=)
JP (1) JP2022526504A (https=)
KR (1) KR20210142665A (https=)
CN (1) CN113677791B (https=)
AU (1) AU2020242305A1 (https=)
BR (1) BR112021018600B1 (https=)
CA (1) CA3134223A1 (https=)
MX (1) MX2021011373A (https=)
WO (1) WO2020188105A1 (https=)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005277831B2 (en) 2004-07-10 2012-11-22 The Institute For Cancer Research Genetically modified human natural killer cell lines
EP1621550A1 (en) * 2004-07-29 2006-02-01 Dompé S.P.A. Tumor-homing cells engineered to produce tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)
GB0724532D0 (en) * 2007-12-17 2008-01-30 Nat Univ Ireland Trail variants for treating cancer
JPWO2010101249A1 (ja) * 2009-03-06 2012-09-10 国立大学法人三重大学 Ｔ細胞の機能増強方法
WO2015121454A1 (en) * 2014-02-14 2015-08-20 Cellectis Cells for immunotherapy engineered for targeting antigen present both on immune cells and pathological cells
EP4406604A3 (en) * 2015-03-05 2024-10-23 Fred Hutchinson Cancer Center Immunomodulatory fusion proteins and uses thereof
JP6974681B2 (ja) * 2015-07-29 2021-12-01 オーエヌケー セラピューティクス リミテッド 細胞傷害性が増加した改変ナチュラルキラー細胞及びナチュラルキラー細胞株
JP7086928B2 (ja) * 2016-07-25 2022-06-20 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ 改変されたナチュラルキラー細胞を生成する方法および使用方法

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Publication number Publication date
EP3942022A1 (en) 2022-01-26
MX2021011373A (es) 2022-01-06
CN113677791A (zh) 2021-11-19
BR112021018600A2 (https=) 2021-11-23
JP2022526504A (ja) 2022-05-25
AU2020242305A1 (en) 2021-09-30
CA3134223A1 (en) 2020-09-24
BR112021018600B1 (pt) 2023-10-17
WO2020188105A1 (en) 2020-09-24
CN113677791B (zh) 2024-12-03
US20220143089A1 (en) 2022-05-12

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