JP2022526504A - 細胞死に対する耐性が増大した改変免疫エフェクター細胞 - Google Patents

細胞死に対する耐性が増大した改変免疫エフェクター細胞 Download PDF

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JP2022526504A
JP2022526504A JP2021556721A JP2021556721A JP2022526504A JP 2022526504 A JP2022526504 A JP 2022526504A JP 2021556721 A JP2021556721 A JP 2021556721A JP 2021556721 A JP2021556721 A JP 2021556721A JP 2022526504 A JP2022526504 A JP 2022526504A
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immune effector
cells
cell
effector cell
trail
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エイモン ピーター オ’ドワイヤー，マイケル
サルカール，スブハシス
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オーエヌケー セラピューティクス リミテッド
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Priority claimed from EP19164241.2A external-priority patent/EP3712257A1/en
Priority claimed from GBGB1917588.4A external-priority patent/GB201917588D0/en
Priority claimed from GBGB2001593.9A external-priority patent/GB202001593D0/en
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JP2021556721A 2019-03-21 2020-03-20 細胞死に対する耐性が増大した改変免疫エフェクター細胞 Pending JP2022526504A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP19164241.2 2019-03-21
EP19164241.2A EP3712257A1 (en) 2019-03-21 2019-03-21 Modified natural killer cells with increased resistance to cell death
GBGB1917588.4A GB201917588D0 (en) 2019-12-02 2019-12-02 modified immune effector cells with increased resistance to cell death
GB1917588.4 2019-12-02
GB2001593.9 2020-02-06
GBGB2001593.9A GB202001593D0 (en) 2020-02-06 2020-02-06 Modified Immune effector cells with increased resistance to cell death
PCT/EP2020/057879 WO2020188105A1 (en) 2019-03-21 2020-03-20 Modified immune effector cells with increased resistance to cell death

Publications (2)

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JP2022526504A true JP2022526504A (ja) 2022-05-25
JP2022526504A5 JP2022526504A5 (https=) 2023-03-17

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JP2021556721A Pending JP2022526504A (ja) 2019-03-21 2020-03-20 細胞死に対する耐性が増大した改変免疫エフェクター細胞

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US (1) US20220143089A1 (https=)
EP (1) EP3942022A1 (https=)
JP (1) JP2022526504A (https=)
KR (1) KR20210142665A (https=)
CN (1) CN113677791B (https=)
AU (1) AU2020242305A1 (https=)
BR (1) BR112021018600B1 (https=)
CA (1) CA3134223A1 (https=)
MX (1) MX2021011373A (https=)
WO (1) WO2020188105A1 (https=)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1621550A1 (en) * 2004-07-29 2006-02-01 Dompé S.P.A. Tumor-homing cells engineered to produce tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)
WO2009077857A2 (en) * 2007-12-17 2009-06-25 Fundació Privada Centre De Regulació Genòmica (Crg) Trail variants for treating cancer
EP2404997A1 (en) * 2009-03-06 2012-01-11 Mie University Method for enhancing function of t cell
WO2017017184A1 (en) * 2015-07-29 2017-02-02 Onkimmune Limited Modified natural killer cells and natural killer cell lines having increased cytotoxicity
JP2017506636A (ja) * 2014-02-14 2017-03-09 セレクティスＣｅｌｌｅｃｔｉｓ 免疫細胞と病的細胞の両方に存在する抗原を標的とするように操作された、免疫療法のための細胞
US20180057795A1 (en) * 2016-07-25 2018-03-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Methods of producing modified natural killer cells and methods of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005277831B2 (en) 2004-07-10 2012-11-22 The Institute For Cancer Research Genetically modified human natural killer cell lines
EP4406604A3 (en) * 2015-03-05 2024-10-23 Fred Hutchinson Cancer Center Immunomodulatory fusion proteins and uses thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1621550A1 (en) * 2004-07-29 2006-02-01 Dompé S.P.A. Tumor-homing cells engineered to produce tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)
WO2009077857A2 (en) * 2007-12-17 2009-06-25 Fundació Privada Centre De Regulació Genòmica (Crg) Trail variants for treating cancer
EP2404997A1 (en) * 2009-03-06 2012-01-11 Mie University Method for enhancing function of t cell
JP2017506636A (ja) * 2014-02-14 2017-03-09 セレクティスＣｅｌｌｅｃｔｉｓ 免疫細胞と病的細胞の両方に存在する抗原を標的とするように操作された、免疫療法のための細胞
WO2017017184A1 (en) * 2015-07-29 2017-02-02 Onkimmune Limited Modified natural killer cells and natural killer cell lines having increased cytotoxicity
US20180057795A1 (en) * 2016-07-25 2018-03-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Methods of producing modified natural killer cells and methods of use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NIKLAS FINNBERG ET AL.: ""DR5 Knockout Mice Are Compromised in Radiation-Induced Apoptosis"", MOLECULAR AND CELLULAR BIOLOGY, vol. 25, no. 5, JPN6024052593, 1 March 2005 (2005-03-01), pages 2000 - 2013, ISSN: 0005630370 *

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Publication number Publication date
EP3942022A1 (en) 2022-01-26
MX2021011373A (es) 2022-01-06
KR20210142665A (ko) 2021-11-25
CN113677791A (zh) 2021-11-19
BR112021018600A2 (https=) 2021-11-23
AU2020242305A1 (en) 2021-09-30
CA3134223A1 (en) 2020-09-24
BR112021018600B1 (pt) 2023-10-17
WO2020188105A1 (en) 2020-09-24
CN113677791B (zh) 2024-12-03
US20220143089A1 (en) 2022-05-12

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