KR20210124237A - Cldn6를 발현하는 암을 치료하기 위한 키메라 항원 수용체-변형된 세포 - Google Patents

Cldn6를 발현하는 암을 치료하기 위한 키메라 항원 수용체-변형된 세포 Download PDF

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KR20210124237A
KR20210124237A KR1020217024706A KR20217024706A KR20210124237A KR 20210124237 A KR20210124237 A KR 20210124237A KR 1020217024706 A KR1020217024706 A KR 1020217024706A KR 20217024706 A KR20217024706 A KR 20217024706A KR 20210124237 A KR20210124237 A KR 20210124237A
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cells
cell
car
cldn6
immune effector
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우구르 사힌
페트라 오엠
벤자민 렝스틀
카싸리나 레인하드
크리스티나 마이클
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비온테크 쎌 & 제네 테라피스 게엠베하
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KR1020217024706A 2019-02-08 2020-02-05 Cldn6를 발현하는 암을 치료하기 위한 키메라 항원 수용체-변형된 세포 Pending KR20210124237A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP2019053156 2019-02-08
EPPCT/EP2019/053156 2019-02-08
PCT/EP2020/052867 WO2020161186A1 (en) 2019-02-08 2020-02-05 Chimeric antigen receptor-modified cells for the treatment of cldn6-expressing cancers

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KR20210124237A true KR20210124237A (ko) 2021-10-14

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US (1) US20220184119A1 (enExample)
EP (2) EP4501351A3 (enExample)
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KR (1) KR20210124237A (enExample)
CN (1) CN113727720A (enExample)
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021129927A1 (en) * 2019-12-23 2021-07-01 Biontech Cell & Gene Therapies Gmbh Treatment with immune effector cells engineered to express an antigen receptor
KR20240133791A (ko) * 2021-12-09 2024-09-04 비온테크 에스이 Cldn6를 발현하는 암을 치료하기 위한 키메라 항원 수용체 변형 세포
WO2024046572A1 (en) * 2022-09-01 2024-03-07 BioNTech SE Chimeric antigen receptor-modified cells for the treatment of cldn6 expressing cancer
CN114478802B (zh) * 2022-01-28 2023-05-26 郑州大学 一种嵌合抗原受体及其应用
CN114410588B (zh) * 2022-01-29 2022-11-04 西安电子科技大学 一种α1β1整合素依赖增强型CAR巨噬细胞及其制备方法和应用
CN120484126B (zh) * 2022-07-28 2025-11-18 乐普创一生物科技（上海）有限公司 抗MerTK抗体及其用途
KR20250046264A (ko) * 2022-07-29 2025-04-02 레전드 바이오테크 아일랜드 리미티드 클라우딘6 겹합 모이어티 및 이의 용도
CN120225555A (zh) * 2022-10-25 2025-06-27 恺兴生命科技(上海)有限公司 抗体及其应用
WO2025184170A1 (en) 2024-02-27 2025-09-04 Overt Bio, Inc. Methods and compositions for improving t cell function in an immunosuppressive environment

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WO2001029058A1 (en) 1999-10-15 2001-04-26 University Of Massachusetts Rna interference pathway genes as tools for targeted genetic interference
US6326193B1 (en) 1999-11-05 2001-12-04 Cambria Biosciences, Llc Insect control agent
WO2001096584A2 (en) 2000-06-12 2001-12-20 Akkadix Corporation Materials and methods for the control of nematodes
WO2013143555A1 (en) 2012-03-26 2013-10-03 Biontech Ag Rna formulation for immunotherapy
US10640569B2 (en) 2013-12-19 2020-05-05 Novartis Ag Human mesothelin chimeric antigen receptors and uses thereof
DK3708579T3 (da) * 2014-04-01 2024-07-22 Biontech Cell & Gene Therapies Gmbh Claudin-6-specifikke immunreceptorer og t-celleepitoper
MA40921A (fr) 2014-11-05 2017-09-12 Abbvie Stemcentrx Llc Récepteurs antigéniques chimériques anti-cldn et procédés d'utilisation
CN106146666B (zh) 2015-03-26 2019-09-06 科济生物医药（上海）有限公司 靶向cldn6的免疫效应细胞及其制备方法和应用
WO2016180467A1 (en) * 2015-05-11 2016-11-17 Biontech Cell & Gene Therapies Gmbh Enhancing the effect of car-engineered t cells by means of nucleic acid vaccination
MX2020002901A (es) * 2017-09-19 2020-07-22 Massachusetts Inst Technology Composiciones para la terapia con celulas t con receptores de antigeno quimerico y usos de las mismas.
CN109206524B (zh) * 2018-09-25 2022-04-05 山东兴瑞生物科技有限公司 抗Claudin18A2嵌合抗原受体、其修饰的T细胞及T细胞制备方法和用途

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LT3920939T (lt) 2025-01-10
US20220184119A1 (en) 2022-06-16
EP3920939B1 (en) 2024-11-13
DK3920939T3 (da) 2025-01-13
HUE070174T2 (hu) 2025-05-28
MX2021009507A (es) 2021-09-08
EP4501351A2 (en) 2025-02-05
SMT202500012T1 (it) 2025-03-12
JP7663500B2 (ja) 2025-04-16
EP4501351A3 (en) 2025-05-07
IL285122A (en) 2021-09-30
EP3920939A1 (en) 2021-12-15
CO2021010347A2 (es) 2022-01-17
BR112021015429A2 (pt) 2021-10-05
WO2020161186A1 (en) 2020-08-13
PL3920939T3 (pl) 2025-02-17
FI3920939T3 (fi) 2025-01-03
CU20210067A7 (es) 2022-03-07
PT3920939T (pt) 2025-01-08
RS66364B1 (sr) 2025-01-31
JP2022520059A (ja) 2022-03-28
AU2020217868A1 (en) 2021-08-12
SG11202108339TA (en) 2021-08-30
CN113727720A (zh) 2021-11-30
CA3129140A1 (en) 2020-08-13
HRP20250016T1 (hr) 2025-03-14
JP2025060882A (ja) 2025-04-10
ES3002958T3 (en) 2025-03-10
SI3920939T1 (sl) 2025-03-31
CL2021002067A1 (es) 2022-03-11

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