KR20210117277A - 인간 넥틴-2에 특이적인 항체 - Google Patents

인간 넥틴-2에 특이적인 항체 Download PDF

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KR20210117277A
KR20210117277A KR1020217023368A KR20217023368A KR20210117277A KR 20210117277 A KR20210117277 A KR 20210117277A KR 1020217023368 A KR1020217023368 A KR 1020217023368A KR 20217023368 A KR20217023368 A KR 20217023368A KR 20210117277 A KR20210117277 A KR 20210117277A
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seq
antibody
sequence
cancer
nectin
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Korean (ko)
Inventor
오페르 만델보임
핀차스 추케르만
스티판 존직
로비스 티하나 레낙
브리릭 파올라 쿠칸
Original Assignee
이슘 리서치 디벨롭먼트 컴퍼니 오브 더 히브루 유니버시티 오브 예루살렘 엘티디.
유니버시티 오브 리예카 패컬티 오브 메디신
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Application filed by 이슘 리서치 디벨롭먼트 컴퍼니 오브 더 히브루 유니버시티 오브 예루살렘 엘티디., 유니버시티 오브 리예카 패컬티 오브 메디신 filed Critical 이슘 리서치 디벨롭먼트 컴퍼니 오브 더 히브루 유니버시티 오브 예루살렘 엘티디.
Publication of KR20210117277A publication Critical patent/KR20210117277A/ko
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
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KR1020217023368A 2019-01-13 2020-01-13 인간 넥틴-2에 특이적인 항체 Pending KR20210117277A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962791808P 2019-01-13 2019-01-13
US62/791,808 2019-01-13
PCT/IL2020/050047 WO2020144697A1 (en) 2019-01-13 2020-01-13 Antibodies specific to human nectin-2

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KR20210117277A true KR20210117277A (ko) 2021-09-28

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US (2) US12545727B2 (https=)
EP (1) EP3908372A1 (https=)
JP (2) JP7606706B2 (https=)
KR (1) KR20210117277A (https=)
CN (2) CN118878685A (https=)
AU (1) AU2020207664B2 (https=)
CA (1) CA3125962A1 (https=)
IL (1) IL284807B2 (https=)
WO (1) WO2020144697A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025234590A1 (ko) * 2024-05-08 2025-11-13 아주대학교산학협력단 Nectin-2에 특이적으로 결합하는 항체 및 이의 용도
WO2025234591A1 (ko) * 2024-05-08 2025-11-13 아주대학교산학협력단 Nectin-2에 결합하는 항체 약물 접합체 및 이의 용도
WO2025254312A1 (ko) * 2024-06-05 2025-12-11 아주대학교산학협력단 Nectin-2에 특이적으로 결합하는 인간화 항체 및 이의 용도

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KR20240152879A (ko) 2022-02-28 2024-10-22 넥틴 테라퓨틱스 리미티드 넥틴-2에 대한 인간화 항체 및 이의 약물 접합체
CN116063498A (zh) * 2022-04-27 2023-05-05 博际生物医药科技(杭州)有限公司 单域抗Nectin-4抗体
EP4716696A1 (en) 2023-05-23 2026-04-01 Fondazione Per L'Istituto Oncologico Di Ricerca (IOR) Monospecific and bispecific antibodies and antibody-drug conjugates targeting nectin2 (cd112) and psma
WO2024240899A1 (en) 2023-05-23 2024-11-28 Universite De Geneve Dual targeting of psma and nectin2 in prostate cancer
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof

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LT3535392T (lt) * 2016-11-02 2024-04-25 Universität Basel Imunologiškai atpažįstami ląstelių paviršiaus variantai, skirti naudoti ląstelių terapijoje
KR20240152879A (ko) 2022-02-28 2024-10-22 넥틴 테라퓨틱스 리미티드 넥틴-2에 대한 인간화 항체 및 이의 약물 접합체

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WO2025234590A1 (ko) * 2024-05-08 2025-11-13 아주대학교산학협력단 Nectin-2에 특이적으로 결합하는 항체 및 이의 용도
WO2025234591A1 (ko) * 2024-05-08 2025-11-13 아주대학교산학협력단 Nectin-2에 결합하는 항체 약물 접합체 및 이의 용도
KR20250161707A (ko) 2024-05-08 2025-11-18 아주대학교산학협력단 Nectin-2에 결합하는 항체 약물 접합체 및 이의 용도
KR20250161706A (ko) 2024-05-08 2025-11-18 아주대학교산학협력단 Nectin-2에 특이적으로 결합하는 항체 및 이의 용도
WO2025254312A1 (ko) * 2024-06-05 2025-12-11 아주대학교산학협력단 Nectin-2에 특이적으로 결합하는 인간화 항체 및 이의 용도
KR20250175021A (ko) 2024-06-05 2025-12-16 아주대학교산학협력단 Nectin-2에 특이적으로 결합하는 인간화 항체 및 이의 용도

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