KR20210068079A - Cd3 및 cd137에 결합할 수 있지만 동시에는 결합하지 않는 항원 결합 분자 - Google Patents

Cd3 및 cd137에 결합할 수 있지만 동시에는 결합하지 않는 항원 결합 분자 Download PDF

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KR20210068079A
KR20210068079A KR1020217012569A KR20217012569A KR20210068079A KR 20210068079 A KR20210068079 A KR 20210068079A KR 1020217012569 A KR1020217012569 A KR 1020217012569A KR 20217012569 A KR20217012569 A KR 20217012569A KR 20210068079 A KR20210068079 A KR 20210068079A
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amino acid
seq
acid sequence
complementarity determining
determining region
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KR1020217012569A
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슈 원 사만사 호
슈 펑
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추가이 세이야쿠 가부시키가이샤
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KR1020217012569A 2018-09-28 2019-09-27 Cd3 및 cd137에 결합할 수 있지만 동시에는 결합하지 않는 항원 결합 분자 KR20210068079A (ko)

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JP2018185120 2018-09-28
JPJP-P-2018-185120 2018-09-28
JPJP-P-2019-104308 2019-06-04
JP2019104308 2019-06-04
PCT/JP2019/038138 WO2020067419A1 (en) 2018-09-28 2019-09-27 Antigen-binding molecules capable of binding cd3 and cd137 but not simultaneously

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CN (1) CN113166247A (de)
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EP4310191A3 (de) 2012-06-14 2024-05-15 Chugai Seiyaku Kabushiki Kaisha Antigenbindendes molekül mit modifizierter fc-region
CN113307873A (zh) 2013-11-11 2021-08-27 中外制药株式会社 含有改变了抗体可变区的抗原结合分子
US11154615B2 (en) 2014-11-11 2021-10-26 Chugai Seiyaku Kabushiki Kaisha Library of antigen-binding molecules including modified antibody variable region
US11952422B2 (en) 2017-12-05 2024-04-09 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule comprising altered antibody variable region binding CD3 and CD137
TWI817974B (zh) 2017-12-28 2023-10-11 日商中外製藥股份有限公司 細胞毒性誘導治療劑
EP4126969A4 (de) 2020-03-31 2024-05-29 Chugai Seiyaku Kabushiki Kaisha Dll3-gerichtete multispezifische antigenbindende moleküle und verwendungen davon
US20230147840A1 (en) * 2020-03-31 2023-05-11 Chugai Seiyaku Kabushiki Kaisha Immune activating multispecific antigen-binding molecules and uses thereof
CA3173519A1 (en) * 2020-03-31 2021-10-07 Vishnu Priyanka Reddy CHICHILI Method for producing multispecific antigen-binding molecules
WO2023036043A1 (zh) * 2021-09-09 2023-03-16 广东东阳光药业有限公司 抗癌结合分子及其应用
WO2023053272A1 (en) * 2021-09-29 2023-04-06 Chugai Seiyaku Kabushiki Kaisha Uses of dll3-targeting multispecific antigen-binding molecules
JPWO2023053282A1 (de) * 2021-09-29 2023-04-06
JP7470760B2 (ja) * 2021-09-29 2024-04-18 中外製薬株式会社 がんの治療に用いるための細胞傷害誘導治療剤
WO2024114676A1 (zh) * 2022-11-29 2024-06-06 江苏恒瑞医药股份有限公司 Cldn18.2/4-1bb结合蛋白及其医药用途

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AU2019347412A1 (en) 2021-05-27
WO2020067419A1 (en) 2020-04-02
JP2022502010A (ja) 2022-01-11
JP2024109792A (ja) 2024-08-14
MA53742A (fr) 2022-01-05
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