KR20210061202A - 벤조나이트릴이 치환된 축합 피리미딘 유도체 및 그의 의약 용도 - Google Patents
벤조나이트릴이 치환된 축합 피리미딘 유도체 및 그의 의약 용도 Download PDFInfo
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- KR20210061202A KR20210061202A KR1020190149117A KR20190149117A KR20210061202A KR 20210061202 A KR20210061202 A KR 20210061202A KR 1020190149117 A KR1020190149117 A KR 1020190149117A KR 20190149117 A KR20190149117 A KR 20190149117A KR 20210061202 A KR20210061202 A KR 20210061202A
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- purin
- halogen
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Classifications
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PCT/IB2020/000970 WO2021099837A1 (en) | 2019-11-19 | 2020-11-19 | Adenosine receptor antagonist compounds |
| MX2022005976A MX2022005976A (es) | 2019-11-19 | 2020-11-19 | Compuestos antagonistas de receptores de adenosina. |
| US17/777,881 US12606564B2 (en) | 2019-11-19 | 2020-11-19 | Adenosine receptor antagonist compounds |
| PCT/IB2020/000948 WO2021099832A2 (en) | 2019-11-19 | 2020-11-19 | Adenosine receptor antagonist compounds |
| BR112022009487A BR112022009487A2 (pt) | 2019-11-19 | 2020-11-19 | Compostos antagonistas do receptor de adenosina |
| CN202211456336.XA CN116425756B (zh) | 2019-11-19 | 2020-11-19 | 腺苷受体拮抗剂化合物及其应用 |
| BR122023020015-2A BR122023020015A2 (pt) | 2019-11-19 | 2020-11-19 | Compostos antagonistas do receptor de adenosina |
| JP2022554968A JP7681616B2 (ja) | 2019-11-19 | 2020-11-19 | アデノシン受容体拮抗薬化合物 |
| TW109140607A TW202132304A (zh) | 2019-11-19 | 2020-11-19 | 腺苷受體拮抗劑化合物 |
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| CN202080080922.1A CN114829363B (zh) | 2019-11-19 | 2020-11-19 | 腺苷受体拮抗剂化合物 |
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| PCT/IB2020/000971 WO2021099838A1 (en) | 2019-11-19 | 2020-11-19 | Adenosine receptor antagonist compounds |
| KR1020247033262A KR102752564B1 (ko) | 2019-11-19 | 2020-11-19 | 아데노신 수용체 길항제 화합물 |
| CL2022001307A CL2022001307A1 (es) | 2019-11-19 | 2022-05-18 | Compuestos antagonistas de receptores de adenosina. |
| AU2023202886A AU2023202886B2 (en) | 2019-11-19 | 2023-05-09 | Adenosine receptor antagonist compounds |
| JP2025079712A JP2025120182A (ja) | 2019-11-19 | 2025-05-12 | アデノシン受容体拮抗薬化合物 |
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Cited By (1)
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| WO2025170158A1 (ko) * | 2024-02-08 | 2025-08-14 | 아이리드비엠에스 주식회사 | Cxcr7 수용체 조절제 및 이의 용도 |
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| US11806350B2 (en) | 2020-11-19 | 2023-11-07 | Ildong Pharmaceutical Co., Ltd. | Prevention and/or treatment of CNS disorders |
| CN119173276A (zh) | 2022-04-13 | 2024-12-20 | 吉利德科学公司 | 用于治疗表达Trop-2的癌症的组合疗法 |
| TW202508599A (zh) * | 2023-05-19 | 2025-03-01 | 南韓商尹諾衛醫藥有限公司 | 用於神經保護或治療α突觸核蛋白及/或神經發炎相關疾病的化合物 |
| WO2025137640A1 (en) | 2023-12-22 | 2025-06-26 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
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| ZA971896B (en) * | 1996-03-26 | 1998-09-07 | Du Pont Merck Pharma | Aryloxy-and arythio-fused pyridines and pyrimidines and derivatives |
| EP0901476A4 (en) * | 1996-03-26 | 2001-08-16 | Du Pont Pharm Co | PYRIDINES AND PYRIMIDINES FUSION ARYLOXY AND ARYLTHIO AND DERIVATIVES THEREOF |
| PL337888A1 (en) * | 1997-07-03 | 2000-09-11 | Du Pont Pharm Co | Imidazoprimidines and imidazopyridines for use in treating neurological disorders |
| US6841549B1 (en) * | 1999-07-02 | 2005-01-11 | Eisai Co., Ltd. | Condensed imidazole compounds and a therapeutic agent for diabetes mellitus |
| GB0100624D0 (en) | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds VII |
| GB0100623D0 (en) | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds IV |
| GB0100621D0 (en) * | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds VI |
| EP1615926A1 (en) * | 2003-04-21 | 2006-01-18 | Ustav Organicke Chemie A Biochemie Akademie Ved Ceske Republiky | (purin-6-yl) amino acid and production method thereof |
| WO2008153947A2 (en) * | 2007-06-07 | 2008-12-18 | Amgen Inc. | Heterocyclic compounds as raf kinase modulators |
| CA2709784A1 (en) * | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| GB0906579D0 (en) * | 2009-04-16 | 2009-05-20 | Vernalis R&D Ltd | Pharmaceuticals, compositions and methods of making and using the same |
| AR077468A1 (es) | 2009-07-09 | 2011-08-31 | Array Biopharma Inc | Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa |
| WO2011050160A1 (en) | 2009-10-22 | 2011-04-28 | Biogen Idec Ma Inc. | Pharmaceuticals, compositions and methods of making and using the same |
| EA201890730A1 (ru) | 2015-09-16 | 2018-10-31 | Локсо Онколоджи, Инк. | Производные пиразолопиримидина в качестве ингибиторов btk для лечения злокачественного новообразования |
| DE102017125533A1 (de) | 2017-10-31 | 2019-05-02 | Helmholtz-Zentrum Dresden - Rossendorf E.V. | 4-(Furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amin-Derivate und deren Verwendung |
| BR122023024273A2 (pt) | 2018-02-27 | 2024-02-20 | Incyte Corporation | Compostos imidazopirimidinas e triazolopirimidinas, seus usos, método para inibir uma atividade de um receptor de adenosina e composição farmacêutica dos mesmos |
| EP4061798B1 (en) | 2019-11-19 | 2025-03-12 | Clariant International Ltd | Solvates of abscisic acid and liquid compositions containing abscisic acid |
| MX2022005914A (es) | 2019-11-19 | 2022-08-04 | Modag Gmbh | Compuestos novedosos para el diagnostico, tratamiento y prevencion de enfermedades asociadas con la agregacion de alfa-sinucleina. |
| US11806350B2 (en) * | 2020-11-19 | 2023-11-07 | Ildong Pharmaceutical Co., Ltd. | Prevention and/or treatment of CNS disorders |
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2019
- 2019-11-19 KR KR1020190149117A patent/KR20210061202A/ko active Pending
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Patent Citations (1)
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| KR100937620B1 (ko) | 2001-11-09 | 2010-01-20 | 씨브이 쎄러퓨틱스, 인코포레이티드 | Ａ２ｂ 아데노신 수용체 길항제 |
Cited By (1)
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| WO2025170158A1 (ko) * | 2024-02-08 | 2025-08-14 | 아이리드비엠에스 주식회사 | Cxcr7 수용체 조절제 및 이의 용도 |
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