KR20200093503A - A buffer composition for preventing acidosis of ruminants - Google Patents

A buffer composition for preventing acidosis of ruminants Download PDF

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KR20200093503A
KR20200093503A KR1020200094063A KR20200094063A KR20200093503A KR 20200093503 A KR20200093503 A KR 20200093503A KR 1020200094063 A KR1020200094063 A KR 1020200094063A KR 20200094063 A KR20200094063 A KR 20200094063A KR 20200093503 A KR20200093503 A KR 20200093503A
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ruminant
feed
ruminants
acidosis
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KR102241952B1 (en
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이상석
정창대
기광석
정하연
김상범
김언태
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순천대학교 산학협력단
대한민국(농촌진흥청장)
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/10Feeding-stuffs specially adapted for particular animals for ruminants
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements

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Abstract

The present invention relates to a buffer composition for preventing acidosis of ruminants. If the buffer composition for preventing acidosis of ruminants, comprising 10-40 wt% of calcium oxide, 2-7 wt% of coral, 10-50 wt% of magnesium oxide, 20-50 wt% of sodium bicarbonate, and 2-7 wt% of yeast, is fed to the ruminants, the acidity in the ruminant of the ruminant is alleviated, and a function of a first stomach is maintained in an optimal state, thereby being used as a feed supplement in ruminant feed to increase the health of the ruminant.

Description

반추동물의 산독증 예방용 완충제 조성물 {A buffer composition for preventing acidosis of ruminants} A buffer composition for preventing acidosis of ruminants}

*본 발명은 반추동물의 산독증 예방용 완충제 조성물에 관한 것으로, 보다 구체적으로는 산화칼슘, 산호, 산화마그네슘, 중탄산나트륨 및 효모를 특정한 비율로 포함하는 반추동물의 산도를 완화시켜주고 제 1위의 기능을 최적상태로 유지시킴으로써 산독증을 예방할 수 있는 반추위 완충제 조성물, 이를 포함하는 반추동물 사료 및 이러한 반추동물 사료를 이용하여 반추동물을 사육하는 방법에 관한 것이다.* The present invention relates to a buffer composition for preventing acidosis in ruminants, and more specifically, to relieve the acidity of ruminants containing calcium oxide, coral, magnesium oxide, sodium bicarbonate and yeast in a specific ratio, and It relates to a rumen buffer composition that can prevent acidosis by maintaining the function in an optimal state, a ruminant feed containing the same, and a method for breeding ruminants using the ruminant feed.

일반적으로 가축용 배합사료는 조단백질, 조지방, 조섬유, 조회분, 칼슘 및 인등을 함유하고 있다. 여기에, 가축의 대사작용에 영향을 주는 약제로서 영양제의 성격을 띤 것으로 비타민제, 칼슘제, 당류, 혈액대용제, 무기질 및 유기산 등이 있다. 또한, 질병예방 및 사료효율 증진을 위하여 항생물질을 첨가하기도 하고 최근에는 동일한 목적으로 유산균제제를 투입하기도 한다.In general, the blended feed for livestock contains crude protein, crude fat, crude fiber, ash, calcium and phosphorus. Here, as a drug that affects the metabolism of livestock, it has the characteristics of a nutrient, and includes vitamins, calcium, sugars, blood substitutes, minerals and organic acids. In addition, antibiotics are added to prevent disease and improve feed efficiency, and recently, lactic acid bacteria are added for the same purpose.

한편, 가축사료의 효율적인 생산과 이용은 양축농가에 있어 대단히 중요한 부분이며 특히 반추가축의 경우 다량의 보조사료(조사료)를 필요로 하기 때문에 더욱 중요하다.On the other hand, efficient production and use of livestock feed is a very important part of farming for livestock, and it is especially important for ruminant livestock because it requires a large amount of supplementary feed (irradiation).

반추동물은 생리특성상 사료급여 방법에 따라 사료 이용성이 크게 달라지므로 (장, 1990), 원료사료의 종류와 배합비율 등에 따라서 사료의 가치가 달라질 수 있다. 정상적인 반추가축의 사양방법은 양질의 조사료 급여를 원칙으로 하고 있으나 우리나라의 현실은 이들 조사료가 부족하기 때문에 저질 조사료인 볏짚에 농후사료를 다급하고 있는 실정으로 그 결과 유산중독, 제4위 전위증, 각화증 및 산독증 등을 일으킬 위험성이 있으며 반추작용이 저하되어 소화율 감소, 소화장애 및 사료섭취량이 감소되고 심할 경우에는 사료섭취를 중단하는 경우가 있다. Due to the physiological characteristics of ruminants, the availability of feed varies greatly depending on the feeding method (Jang, 1990), so the value of feed may vary depending on the type of feed and the mixing ratio. Normal ruminant livestock specifications are based on the provision of high-quality feedstocks, but in reality, Korea is in need of high-quality feedstocks. And there is a risk of causing acidosis and the like, the ruminant action is reduced, the digestion rate is reduced, digestive disorders and feed intake are reduced, and in severe cases, feed intake may be stopped.

현재 반추동물(反騶動物)의 사육시 양질의 조사료(粗飼料)가 부족함에 따라 점진적으로 농후사료(濃厚飼料)를 위주로 급여하고 있으며, 이러한 사육체계하에서는 반추위(反騶胃)가 점차 산성화되어 급성 산독증이 발생하게 된다. At present, as ruminant animals are raised, the quality of feedstock is insufficient, and the feedstock is gradually supplied mainly. Under this breeding system, rumen is gradually acidified and acute. Acidosis develops.

이러한 급성 산독증은 농후사료 대량섭취로 제1위 내에 젖산이 과도하게 생성되어 발생하며, 제1위 내 pH가 낮아지며 증상으로는 심한탈수 증상과 설사를 일으키며, 더욱 심해지면 호흡수와 맥박수가 증가하고 급성 고창증 증세를 나타낸다. 만성인 경우 지속적인 농후사료 과다급여로 조사료 섭취량이 떨어져 반추위 pH가 4.5~5.5 까지 떨어지며, 만성적인 과산증은 만성고창증, 인산염뇨에 의한 뇨석증을 일으키고, 제1위 내 이상 발효과정에서 생성된 히스타민으로 발굽의 혈액순환장애가 초래되어 제엽염이 발생하게 된다. This acute acidosis is caused by excessive production of lactic acid in the first place due to a large intake of concentrated feed, and the pH in the first place is lowered, causing severe dehydration symptoms and diarrhea, and as it gets worse, respiratory and pulse rates increase. Indicates acute bloating symptoms. In chronic cases, the intake of feedstock falls due to continuous overfeeding, and the rumen pH falls to 4.5~5.5. Chronic hyperacidity causes chronic bloating, ureuria caused by phosphate urine, and histamine produced during abnormal fermentation within the first place. As a result, blood circulation disorders of the hoof are caused, and conjunctivitis occurs.

또한, 반추위내 빠른 전분 분해 시 반추위내 미생물중 Streptococcus bovis의 증가, Escherichia coli에 의한 endotoxin 분비, 반추위내 삼투압증가 및 휘발성지방산 축적, 젖산이용 Megasphea elsdenii의 성장저해 등 반추위내 미생물 균총의 변화 및 유용 미생물의 저해가 발생하게 된다. In addition, changes in microbial microflora in the rumen and useful microorganisms, such as increased streptococcus bovis among microorganisms in the rumen, increased endotoxin by Escherichia coli , increased osmotic pressure and volatile fatty acid accumulation in the rumen, and inhibited growth of Megasphea elsdenii using lactic acid Inhibition occurs.

이러한 문제점을 보완하기 위하여 완충제를 급여하면 반추위내 pH를 적정수준으로 유지하므로서 사료섭취량과 소화율향상 및 젖소의 유지율을 향상시킬 수 있다. 유우에게 완전혼합사료(TMR)를 급여하게 되면 균형된 사료를 섭취함으로서 반추위내 pH를 정상적으로 (6.2∼6.8) 유지시켜 미생물체 단백질 합성이 왕성하게 됨으로서 유효한 휘발성 지방산(VFA)의 생성, 효율적인 조사료 이용 및 소화계통의 질병을 예방하고 사료의 이용율을 극대화함으로 생산성이 증진된다고 보고하였다 (Holter 등, 1977).To compensate for this problem, feeding the buffer can maintain the pH in the rumen at an appropriate level, thereby improving feed intake, digestibility and maintenance of cows. When fully mixed feed (TMR) is fed to the cow, the pH in the rumen is normally maintained (6.2 to 6.8) by ingesting a balanced feed, thereby producing a volatile fatty acid (VFA) that is effective by generating effective volatile fatty acids (VFAs), and It has been reported that productivity is improved by preventing diseases of the digestive system and maximizing the utilization rate of feed (Holter et al., 1977).

그러나, TMR 사료만으로는 완전한 효과를 얻기 어려우므로 TMR 제조시 완충제를 첨가하는 것이 보다 좋은 것으로 밝혀졌다. Esdale과 Satter (1972)는 NaHCO3 첨가가 반추위내 pH와 VFA 농도에 관한 연구에서 홀스타인에 NaHCO3를 반추위내 9∼12mole씩 계속적인 주입은 pH를 상승시키고 총휘발성 지방산 함량은 오히려 감소시킨다고 보고하였고, Kilmer 등(1980)은 경산우, 미경산우의 유우사료에 NaHCO3 0.7%를 첨가하였을 때 전체(Total)-VFA 함량은 증가하였다고 보고하였으며, Erdman등 (1982)은 농후사료와 옥수수 사일리지(silage)(60:40) 사료에 NaHCO3 1%를 첨가하였 때 ADF의 소화율을 증가시켰으며, 반추위액의 pH 하락을 방지하였다고 보고하였다. However, it was found that it is better to add a buffer in the preparation of TMR since it is difficult to obtain a complete effect only with TMR feed. Esdale and Satter (1972) reported that NaHCO 3 addition increased the pH and decreased total volatile fatty acid content by continuously injecting 9 to 12 moles of NaHCO 3 in the rumen in Holstein in a study of pH and VFA concentration in the rumen. , Kilmer et al. (1980) reported that total-VFA content increased when 0.7% NaHCO 3 was added to dairy cattle of light and non-light cattle, and Erdman et al. (1982) of rich feed and corn silage. (60:40) It was reported that the addition of 1% NaHCO 3 to the feed increased the digestibility of ADF and prevented the drop in pH of rumen fluid.

이에 본 발명자들은 반추동물의 반추위내 산도를 완화시켜주고 제 1위의 기능을 최적상태로 유지시킴으로써 산독증을 예방할 수 있는 반추위 완충제를 개발하기 위해 계속 연구를 진행하던 중 산화칼슘, 산호, 산화마그네슘, 중탄산나트륨 및 효모를 특정한 비율로 포함하는 완충제 조성물이 반추동물의 반추위내 산도를 완화시켜주고 제 1위의 기능을 최적상태로 유지시킬 수 있다는 사실을 발견함으로써 본 발명을 완성하였다.Accordingly, the present inventors continued to research to develop a rumen buffer that can prevent acidosis by alleviating acidity in the rumen of the ruminant and maintaining the first function in an optimal state. Calcium oxide, coral, magnesium oxide, The present invention was completed by discovering that a buffer composition comprising sodium bicarbonate and yeast in a specific ratio can alleviate the acidity in the rumen of a ruminant and maintain the function of the first position in an optimal state.

따라서, 본 발명에서 해결하고자 하는 기술적 과제는 반추동물의 위(胃)내 산도를 완화시켜주고 제 1위의 기능을 최적상태로 유지시킬 수 있는 반추동물의 산독증 예방용 완충제를 제공하기 위한 것이다.Therefore, the technical problem to be solved in the present invention is to provide a buffer for preventing acidosis of ruminants, which can relieve the acidity in the stomach of ruminants and maintain the first function in an optimal state.

본 발명에서 해결하고자 하는 다른 기술적 과제는 상기 반추동물의 산독증 예방용 완충제를 포함하는 반추동물 사료를 제공하기 위한 것이다.Another technical problem to be solved in the present invention is to provide a ruminant feed containing a buffer for preventing acidosis of the ruminant.

본 발명에서 해결하고자 하는 또다른 기술적 과제는 상기 반추동물의 산독증 예방용 완충제를 포함하는 반추동물 사료를 이용한 반추동물의 사육방법을 제공하기 위한 것이다.Another technical problem to be solved in the present invention is to provide a method for breeding ruminants using ruminant feed containing a buffer for preventing acidosis of ruminants.

상기한 기술적 과제를 해결하기 위하여, 본 발명에서는 산화칼슘 10 내지 40 중량%, 산호 2 내지 7 중량%, 산화마그네슘 10 내지 50 중량%, 중탄산나트륨 20 내지 50 중량% 및 효모 2 내지 7 중량%를 포함하는 반추동물의 산독증 예방용 완충제 조성물을 제공한다.In order to solve the above technical problem, in the present invention, 10 to 40% by weight of calcium oxide, 2 to 7% by weight of coral, 10 to 50% by weight of magnesium oxide, 20 to 50% by weight of sodium bicarbonate, and 2 to 7% by weight of yeast It provides a buffer composition for preventing acidosis of ruminants containing.

상기한 다른 기술적 과제를 해결하기 위하여, 본 발명에서는 상기 반추동물의 산독증 예방용 완충제를 포함하는 반추동물 사료를 제공한다.In order to solve the above other technical problems, the present invention provides a ruminant feed containing a buffer for preventing acidosis of the ruminant.

상기한 또다른 기술적 과제를 해결하기 위하여, 본 발명에서는 상기 반추동물의 산독증 예방용 완충제를 포함하는 반추동물 사료를 이용하여 반추동물을 사육하는 방법을 제공한다.In order to solve the above another technical problem, the present invention provides a method for breeding ruminants using a ruminant feed containing a buffer for preventing acidosis of the ruminants.

본 발명의 반추동물의 산독증 예방용 조성물은 반추동물의 반추위내 산도를 중화 및 완화시킴으로써 반추동물의 산독증을 예방할 수 있다.The composition for preventing acidosis in ruminants of the present invention can prevent acidosis in ruminants by neutralizing and alleviating the acidity in the rumen of the ruminants.

본 발명의 반추동물의 산독증 예방용 조성물은 산화칼슘 10 내지 40 중량%, 산호 2 내지 7 중량%, 산화마그네슘 10 내지 50 중량%, 중탄산나트륨 20 내지 50 중량% 및 효모 2 내지 7 중량%를 포함하며, 바람직하게는 산화칼슘 20 내지 30 중량%, 산호 3 내지 6 중량%, 산화마그네슘 20 내지 40 중량%, 중탄산나트륨 30 내지 40 중량% 및 효모 3 내지 6 중량%를 포함한다.The composition for preventing acidosis of ruminants of the present invention includes 10 to 40% by weight of calcium oxide, 2 to 7% by weight of coral, 10 to 50% by weight of magnesium oxide, 20 to 50% by weight of sodium bicarbonate, and 2 to 7% by weight of yeast Preferably, 20 to 30% by weight of calcium oxide, 3 to 6% by weight of coral, 20 to 40% by weight of magnesium oxide, 30 to 40% by weight of sodium bicarbonate and 3 to 6% by weight of yeast.

상기 산화칼슘, 산호(coral), 산화마그네슘, 중탄산나트륨 및 효모의 각 함량이 상기 범위를 벗어날 경우 반추위내 산도의 중화 및 완충 효과를 기대할 수 없다.When each content of the calcium oxide, coral, magnesium oxide, sodium bicarbonate, and yeast is outside the above range, it is not possible to expect a neutralization and buffering effect of acidity in the rumen.

본 발명에서 용어 "반추위 동물"이란, 우제목에 속하는 동물 중에서 반추위를 갖는 동물을 의미한다. 상기 우제목은 크게 9개 과(멧돼지과, 미국멧돼지과, 하마과, 낙타과, 애기사슴과, 사슴과, 기린과, 영양붙이과 및 소과)로 구분되는데, 이중에서 낙타과(단봉낙타, 쌍봉낙타, 라마, 알파카, 과나코, 비쿠냐 등), 애기사슴과(애기사슴, 쥐사슴 등), 사슴과(사슴, 순록, 노루, 고라니, 엘크, 무우스 등) , 기린과(기린 또는 오카피) 및 소과(한우, 젖소, 야크, 들소, 버팔로, 임팔라, 가우르, 물소, 염소, 양, 산양, 영양 등)의 동물들이 반추위 동물이라고 호칭될 수 있다. In the present invention, the term "ruminant animal" means an animal having rumen among the animals belonging to the subheading. The above subheadings are largely divided into nine families (boar family, American wild boar family, hippo family, camel family, baby deer family, deer family, giraffe family, nutridae family, and bovine family). , Guanaco, Vicuña, etc., baby deer (baby deer, rat deer, etc.), deer family (deer, reindeer, roe deer, elk, elk, moose, etc.), giraffe (giraffe or okapi) and bovine (Korean beef, Animals of dairy cows, yak, bison, buffalo, impala, gaur, buffalo, goats, sheep, goats, antelopes, etc.) may be called ruminants.

본 발명에서 용어 "반추위"란, 우제목의 일부 동물에서 볼 수 있는 특수한 소화관으로, 일명 되새김을 하기 위해 혹위, 벌집위, 겹주름위, 및 주름위의 4개의 방으로 구성된 위장을 의미한다. 일명 되새김위라고도 하며, 한번 삼킨 음식물을 다시 입 안으로 토하여 잘 씹은 후에 삼키는 것을 반추라고 하고, 이런 반추를 가능하게 하는 위장이기 때문에 반추위라고 명명되었다. 상기 반추위에는 미생물이 공생하고 있어서 일반적인 동물들이 소화하지 못하는 식물의 셀룰로스를 분해하거나, 솔라닌의 독성을 나타내지 않고 흡수할 수 있다.In the present invention, the term "rumen" is a special digestive tract that can be seen in some animals of the right head, aka stomach, honeycomb, folds, and wrinkles, to mean a stomach composed of four rooms. It is also known as a sauteed stomach, and it is called ruminant because it is the stomach that swallows food once swallowed and chews it well and swallows it. Microorganisms are symbiotic in the rumen, which can decompose cellulose in plants that are not digested by ordinary animals, or absorb without showing the toxicity of solanine.

본 발명의 반추동물 산독증 예방용 완충제 조성물은 펠릿 형태 또는 블록 형태 등 형태에 무관하게 사용될 수 있으며, 반충동물의 사료에 사료보조제로서 사용될 수 있다.The buffer composition for preventing ruminant acidosis of the present invention may be used irrespective of a form such as a pellet form or a block form, and may be used as a feed supplement for feed of a ruminant animal.

본 발명에서 용어 "사료보조제"란, 사료 자체로 사용되거나 사료에 첨가하여 반추위 동물의 생산성 향상이나 건강을 증진시킬 수 있는 물질을 의미한다. In the present invention, the term "feed supplement" means a substance that can be used as feed itself or added to the feed to improve the productivity or health of ruminant animals.

본 발명에서 용어 "사료"란, 반추위 동물이 먹고, 섭취하며, 소화시키기 위한 또는 이에 적당한 임의의 천연 또는 인공 구정식, 한끼식 등 또는 상기 한끼식의 성분을 의미한다. In the present invention, the term "feed" means any natural or artificial Chinese New Year meal, one meal or the like or a component of the one meal for ruminant animals to eat, eat, and digest.

본 발명에 있어서, 상기 사료는 본 발명의 반추동물 산독증 예방용 완충제 조성물을 통상의 원료사료에 가하여 제조된 반추위 동물 사육용 사료로 해석될 수 있고, 상기 사료는 반추위 동물의 육량을 증대시키는 효과를 나타낼 수 있다.In the present invention, the feed may be interpreted as a feed for breeding ruminant animals prepared by adding the buffer composition for preventing ruminant acidosis of the present invention to a normal raw material feed, and the feed has an effect of increasing the meat mass of the ruminant animal. Can be represented.

본 발명에서 용어 "원료사료"란, 상기 사료첨가용 조성물이 첨가되는 사료를 의미한다.In the present invention, the term "raw material feed" means a feed to which the composition for feed addition is added.

본 발명에 있어서, 상기 원료사료는 상기 사료첨가제가 부가되어 반추위 동물의 육량을 증대시킬 수 있는 효과를 나타내는 한 특별히 이에 제한되지 않으나, 일례로서 쌀, 발효대두분, 대두, 이탈리안그라스, 수단그라스, 호밀, 볏짚, 옥수수, 소맥피, 쌀겨, 당맥피 등을 단독으로 또는 조합하여 주성분으로 포함하는 배합사료가 될 수 있고, 이들 주성분은 반추위 동물용 원료사료에 일반적으로 사용되는 적절한 범위로 포함될 수 있다.In the present invention, the raw material feed is not particularly limited as long as the feed additive is added to show the effect of increasing the meat volume of the ruminant animal, but, for example, rice, fermented soy flour, soybean, Italiangrass, Sudangrass, The rye, rice straw, corn, wheat bark, rice bran, sugar bark, etc., alone or in combination, may be a blended feed containing as a main component, and these main components may be included in an appropriate range generally used for ruminant animal feed. .

본 발명의 반추동물 산독증 예방용 완충제 조성물은 사료의 제조에 사용될 수 있는 부형제, 희석제를 추가로 포함할 수 있다. 상기 부형제 및 희석제로는 락토즈, 덱스트로즈, 수크로스, 솔비톨, 만니톨, 자일리톨, 에리스리톨, 말티톨, 전분, 아카시아 고무, 알지네이트, 젤라틴, 칼슘 포스페이트, 칼슘 실리케이트, 셀룰로즈, 메틸 셀룰로즈, 미정질 셀룰로스, 폴리비닐 피롤리돈, 물, 메틸히드록시벤조에이트, 프로필히드록시벤조에이트, 탈크, 마그네슘 스테아레이트, 광물유, 스테비아 추출물 및 천연소재 추출물을 들 수 있다. The buffer composition for preventing ruminant acidosis of the present invention may further include excipients and diluents that can be used in the preparation of feed. The excipients and diluents include lactose, dextrose, sucrose, sorbitol, mannitol, xylitol, erythritol, maltitol, starch, acacia rubber, alginate, gelatin, calcium phosphate, calcium silicate, cellulose, methyl cellulose, microcrystalline cellulose, And polyvinyl pyrrolidone, water, methylhydroxybenzoate, propylhydroxybenzoate, talc, magnesium stearate, mineral oil, stevia extract and natural material extract.

본 발명은 다른 하나의 양태로서 상기 반추동물 산독증 예방용 완충제 조성물을 포함하는 반추동물의 사료 및 상기 사료를 이용한 반추동물의 사육방법을 제공한다. In another aspect, the present invention provides a ruminant feed containing the buffer composition for preventing ruminant acidosis, and a method for breeding a ruminant using the feed.

상술한 바와 같이, 본 발명의 반추동물 산독증 예방용 완충제 조성물은 반추위 동물에 섭식시킬 경우, 반추동물의 반추위내 산도를 완화시켜주고 제 1위의 기능을 최적상태로 유지시킬 수 있는 바, 이를 반추동물의 건강 증대를 위하여 반추동물 사료에 사료보조제로서 사용할 수 있다.As described above, when the buffer composition for preventing ruminant acidosis of the present invention is fed to a ruminant animal, the acidity in the rumen of the ruminant can be relieved and the function of the first place can be maintained in an optimal state. It can be used as feed supplement in ruminant feed to increase animal health.

이와 같이, 산화칼슘, 산호, 산화마그네슘, 중탄산나트륨 및 효모를 특정비율로 포함하는 본 발명의 반추동물 산독증 예방용 완충제 조성물은 반추위 동물에 섭식시킬 경우, 반추동물의 반추위내 산도를 완화시켜주고 제 1위의 기능을 최적상태로 유지시킬 수 있는 바, 이를 반추동물의 건강 증대를 위하여 반추동물 사료에 사료보조제로서 사용할 수 있다.As such, the buffer composition for preventing ruminant acidosis of the present invention comprising calcium oxide, coral, magnesium oxide, sodium bicarbonate, and yeast at a specific ratio, when fed to ruminant animals, relieves the acidity in the rumen of ruminants and provides The function of the first place can be maintained in an optimal state, which can be used as a feed supplement in ruminant feed to increase the health of ruminants.

이하, 본 발명의 이해를 돕기 위하여 실시예 등을 들어 상세하게 설명하기로 한다. 그러나, 본 발명에 따른 실시예들은 여러 가지 다른 형태로 변형될 수 있으며, 본 발명의 범위가 하기 실시예들에 한정되는 것으로 해석되어서는 안 된다. 본 발명의 실시예들은 당업계에서 평균적인 지식을 가진 자에게 본 발명을 보다 완전하게 설명하기 위해 제공되는 것이다. Hereinafter, examples and the like will be described in detail to help understanding of the present invention. However, the embodiments according to the present invention may be modified in various other forms, and the scope of the present invention should not be interpreted as being limited to the following examples. The embodiments of the present invention are provided to more fully describe the present invention to those skilled in the art.

<실시예 1> 반추동물 산독증 예방용 완충제 조성물 조제<Example 1> Preparation of buffer composition for preventing ruminant acidosis

하기 표 1에 나타낸 조성비율에 따라 산화칼슘, 산호, 산화마그네슘, 중탄산나트륨 및 효모를 포함하는 반추동물 산독증 예방용 완충제 조성물을 제조하였다.A buffer composition for preventing ruminant acidosis, including calcium oxide, coral, magnesium oxide, sodium bicarbonate and yeast, was prepared according to the composition ratio shown in Table 1 below.

Trt Trt Chemical (%)Chemical (%) 산화칼슘Calcium oxide 산호coral 산화마그네슘Magnesium oxide 중탄산나트륨 Sodium bicarbonate 효모leaven T1T1 3030 55 3030 3030 55 T2T2 2525 55 2525 4040 55 T3T3 3030 55 2525 3535 55 T4T4 2525 55 3030 3535 55 T5T5 2020 55 3030 4040 55 T6T6 3030 55 2020 4040 55 T7T7 2020 55 4040 3030 55

<시험예 1> 반추동물 산독증 예방용 완충제 조성물의 중화 및 완화 효과 측정반추위내 산성이 강한 Acetic acid를 첨가하여, 상기 실시예 1에서 제조된 반추동물 산독증 예방용 완충제 조성물의 중화 및 완화 효과를 측정하였다. 그 결과는 하기 표 2에 나타내었다. <Test Example 1> Measurement of neutralization and mitigation effect of buffer composition for ruminant acid poisoning by adding acetic acid having strong acidity in rumen, measuring neutralization and relaxation effect of buffer composition for ruminant acidosis prevention prepared in Example 1 above Did. The results are shown in Table 2 below.

Sample (2 g)Sample (2 g) T1T1 T2T2 T3T3 T4T4 T5T5 T6T6 T7T7 A사제품Company A B사제품Company B initial pHinitial pH 9.709.70 9.519.51 9.579.57 9.639.63 9.559.55 9.499.49 9.869.86 10.4010.40 11.2011.20 mls 2N Acetic acid to 6.5mls 2N Acetic acid to 6.5 6.576.57 5.175.17 4.874.87 4.074.07 5.005.00 3.933.93 8.608.60 4.104.10 7.707.70 mls 2N Acetic acid from initial pH to pH 5.5mls 2N Acetic acid from initial pH to pH 5.5 18.7718.77 16.3316.33 14.8714.87 17.4717.47 19.2019.20 14.3714.37 22.9022.90 14.6714.67 17.9717.97 mls 2N Acetic acid from pH 6.5 to pH 5.5mls 2N Acetic acid from pH 6.5 to pH 5.5 12.2012.20 11.1711.17 10.0010.00 13.4013.40 14.2014.20 10.4310.43 14.3014.30 10.5710.57 10.2710.27 6.5 (Neutralizing capacity - mMol/L)6.5 (Neutralizing capacity-mMol/L) 13.1313.13 10.3310.33 9.739.73 8.138.13 10.0010.00 7.877.87 17.2017.20 8.208.20 15.4015.40 5.5 (Buffer capacity - mMol/L)5.5 (Buffer capacity-mMol/L) 37.5337.53 32.6732.67 29.7329.73 34.9334.93 38.4038.40 28.7328.73 45.8045.80 29.3329.33 35.9335.93

초기 pH는 B사 제품이 가장 높았으나, pH 6.5로 조정하기 위한 2N Acetic acid 양은 T7이 많았다. pH 5.5로 낮추기 위해 첨가된 2N Acetic acid양 역시 T7, T5 및 T4 순으로 높았다. 6.5 (Neutralizing capacity - mMol/L) 와 5.5 (Buffer capacity - mMol/L)도 T7, T5 및 T4 순으로 높았다. 타사 제품과 비교에서는 T7과 T5가 더 높은 버퍼능력을 보였다.The initial pH was the highest in the B company, but the amount of 2N Acetic acid to adjust to pH 6.5 was high in T7. The amount of 2N Acetic acid added to lower to pH 5.5 was also high in the order of T7, T5 and T4. 6.5 (Neutralizing capacity-mMol/L) and 5.5 (Buffer capacity-mMol/L) were also higher in the order of T7, T5 and T4. Compared to other products, T7 and T5 showed higher buffer capacity.

Claims (3)

산화칼슘 20 중량%, 산호 5 중량%, 효모 5 중량%, 산화마그네슘 30 중량% 및 중탄산나트륨 40 중량%, 또는 산화칼슘 20 중량%, 산호 5 중량%, 효모 5 중량%, 산화마그네슘 40 중량% 및 중탄산나트륨 30 중량%로 이루어진 반추동물의 산독증 예방용 완충제 조성물.20% by weight of calcium oxide, 5% by weight of coral, 5% by weight of yeast, 30% by weight of magnesium oxide and 40% by weight of sodium bicarbonate, or 20% by weight of calcium oxide, 5% by weight of coral, 5% of yeast, 40% by weight of magnesium oxide And sodium bicarbonate 30% by weight of a buffer composition for preventing acidosis of ruminants. 제 1 항에 따른 반추동물의 산독증 예방용 완충제 조성물을 포함하는 반추동물용 사료.A ruminant feed comprising a buffer composition for preventing acidosis of ruminants according to claim 1. 제 2 항에 따른 반추동물용 사료를 이용하여 반추동물을 사육하는 방법.Method for breeding ruminants using the ruminant feed according to claim 2.
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KR100190516B1 (en) * 1996-08-26 1999-06-01 고영두 Buffer agent for livestocks
KR20150083225A (en) * 2014-01-09 2015-07-17 씨제이제일제당 (주) Livestock assorted feed with enhanced nutrients and manufacturing method thereof
KR101756039B1 (en) * 2016-11-21 2017-07-10 이성수 Manufacturing method of composition of feed for ruminant
JP2018088895A (en) * 2016-12-06 2018-06-14 株式会社アグリワールド Additive for livestock feed, livestock feed and method for producing the same

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Publication number Priority date Publication date Assignee Title
EP4079813A1 (en) * 2021-04-23 2022-10-26 Omya International AG Buffer composition comprising a first and a second buffer component
WO2022223804A1 (en) * 2021-04-23 2022-10-27 Omya International Ag Buffer composition comprising a first and a second buffer component

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