KR20200091432A - 망막 색소 상피에서의 유전자의 특이적 발현을 위한 프로모터 SynPIII - Google Patents
망막 색소 상피에서의 유전자의 특이적 발현을 위한 프로모터 SynPIII Download PDFInfo
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| WO2024225830A1 (ko) * | 2023-04-27 | 2024-10-31 | 한국생명공학연구원 | 유전자의 망막 세포 내 발현을 위한 프로모터 및 이를 포함하는 벡터 시스템 |
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| PT2271369E (pt) | 2008-04-18 | 2014-07-10 | Novartis Forschungsstiftung | Novas ferramentas terapêuticas e métodos para tratar a cegueira |
| US10941417B2 (en) | 2015-04-30 | 2021-03-09 | Friedrich Miescher Institute For Biomedical Research | Promoter for the specific expression of genes in Müller cells |
| ES2926677T3 (es) | 2015-09-15 | 2022-10-27 | Friedrich Miescher Institute For Biomedical Res | Herramientas y métodos terapéuticos novedosos para tratar la ceguera mediante el direccionamiento a los fotorreceptores |
| EP3362101B1 (en) | 2015-10-14 | 2021-05-19 | Friedrich Miescher Institute for Biomedical Research | Promoter for the specific expression of genes in retinal endothelial cells |
| WO2017093931A1 (en) | 2015-12-03 | 2017-06-08 | Friedrich Miescher Institute For Biomedical Research | Synp159, a promoter for the specific expression of genes in rod photoreceptors |
| CA3006952A1 (en) | 2015-12-03 | 2017-06-08 | Friedrich Miescher Institute For Biomedical Research | Synp161, a promoter for the specific expression of genes in rod photoreceptors |
| ES2886664T3 (es) | 2015-12-03 | 2021-12-20 | Friedrich Miescher Institute For Biomedical Res | SynP162, un promotor para la expresión específica de genes en fotorreceptores de bastón |
| ES2900486T3 (es) | 2015-12-03 | 2022-03-17 | Friedrich Miescher Institute For Biomedical Res | SynP160, un promotor para la expresión específica de genes en los fotorreceptores de los bastones |
| RU2766353C2 (ru) | 2016-11-02 | 2022-03-15 | Фридрих Мишер Инститьют Фор Байомедикал Рисерч | Synp198, промотор для специфической экспрессии генов в ганглионарных клетках сетчатки, избирательных в отношении направления |
| WO2018146588A1 (en) | 2017-02-08 | 2018-08-16 | Friedrich Miescher Institute For Biomedical Research | Synp88, a promoter for the specific expression of genes in retinal ganglion cells |
| CA3082080A1 (en) | 2017-11-15 | 2019-05-23 | Friedrich Miescher Institute For Biomedical Research | Primate retinal pigment epithelium cell-specific promoter |
| CN111542611A (zh) | 2017-11-30 | 2020-08-14 | 弗里德里克·米谢尔生物医学研究所 | 用于使基因在视网膜色素上皮中特异性表达的启动子SynPIII |
| WO2024110770A1 (en) * | 2022-11-22 | 2024-05-30 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A new promoter for retinal pigment epithelium (rpe) targeted gene therapy |
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| CA2346262A1 (en) * | 1998-09-17 | 2000-03-23 | University Of Florida | Methods for treatment of degenerative retinal diseases |
| EP3437473A1 (en) | 2006-05-04 | 2019-02-06 | Wayne State University | Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids |
| EP1891976A1 (en) | 2006-08-23 | 2008-02-27 | Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute for Biomedical Research | Use of light sensitive genes |
| WO2009112448A1 (en) | 2008-03-11 | 2009-09-17 | Novartis Forschungsstiftung, Zweigniederlassung | Novel tool for the analysis of neural circuits |
| PT2271369E (pt) | 2008-04-18 | 2014-07-10 | Novartis Forschungsstiftung | Novas ferramentas terapêuticas e métodos para tratar a cegueira |
| AU2012204266C1 (en) | 2011-01-07 | 2017-12-21 | Applied Genetic Technologies Corporation | Promoters, expression cassettes, vectors, kits, and methods for the treatment of achromatopsia and other diseases |
| WO2014033095A1 (en) * | 2012-08-27 | 2014-03-06 | Friedrich Miescher Institute For Biomedical Research | Retinal off circuit-specific promoter |
| WO2015118507A1 (en) | 2014-02-10 | 2015-08-13 | Friedrich Miescher Institute For Biomedical Research | Aii retinal amacrine cell-specific promoter |
| ES2748282T3 (es) | 2014-02-11 | 2020-03-16 | Friedrich Miescher Institute For Biomedical Res | Promotor específico de células de Müller |
| GB201502137D0 (en) * | 2015-02-09 | 2015-03-25 | Ucl Business Plc | Treatment |
| US10941417B2 (en) | 2015-04-30 | 2021-03-09 | Friedrich Miescher Institute For Biomedical Research | Promoter for the specific expression of genes in Müller cells |
| ES2926677T3 (es) | 2015-09-15 | 2022-10-27 | Friedrich Miescher Institute For Biomedical Res | Herramientas y métodos terapéuticos novedosos para tratar la ceguera mediante el direccionamiento a los fotorreceptores |
| EP3362101B1 (en) | 2015-10-14 | 2021-05-19 | Friedrich Miescher Institute for Biomedical Research | Promoter for the specific expression of genes in retinal endothelial cells |
| CA3006952A1 (en) | 2015-12-03 | 2017-06-08 | Friedrich Miescher Institute For Biomedical Research | Synp161, a promoter for the specific expression of genes in rod photoreceptors |
| ES2900486T3 (es) | 2015-12-03 | 2022-03-17 | Friedrich Miescher Institute For Biomedical Res | SynP160, un promotor para la expresión específica de genes en los fotorreceptores de los bastones |
| WO2017093931A1 (en) | 2015-12-03 | 2017-06-08 | Friedrich Miescher Institute For Biomedical Research | Synp159, a promoter for the specific expression of genes in rod photoreceptors |
| ES2886664T3 (es) | 2015-12-03 | 2021-12-20 | Friedrich Miescher Institute For Biomedical Res | SynP162, un promotor para la expresión específica de genes en fotorreceptores de bastón |
| JP6966442B2 (ja) * | 2015-12-04 | 2021-11-17 | ソルボンヌ・ユニヴェルシテSorbonne Universite | プロモーター及びその使用 |
| WO2017199156A1 (en) | 2016-05-17 | 2017-11-23 | Friedrich Miescher Institute For Biomedical Research | Novel therapeutic tools and methods for treating blindness |
| RU2766353C2 (ru) | 2016-11-02 | 2022-03-15 | Фридрих Мишер Инститьют Фор Байомедикал Рисерч | Synp198, промотор для специфической экспрессии генов в ганглионарных клетках сетчатки, избирательных в отношении направления |
| EP3548094A1 (en) | 2016-12-01 | 2019-10-09 | Friedrich Miescher Institute for Biomedical Research | Synpi, a promoter for the specific expression of genes in interneurons |
| CN110072559A (zh) | 2016-12-01 | 2019-07-30 | 弗里德里克·米谢尔生物医学研究所 | 用于使基因在中间神经元中特异性表达的启动子SynP107 |
| WO2018146588A1 (en) | 2017-02-08 | 2018-08-16 | Friedrich Miescher Institute For Biomedical Research | Synp88, a promoter for the specific expression of genes in retinal ganglion cells |
| CA3082080A1 (en) | 2017-11-15 | 2019-05-23 | Friedrich Miescher Institute For Biomedical Research | Primate retinal pigment epithelium cell-specific promoter |
| JP7390290B2 (ja) | 2017-11-30 | 2023-12-01 | フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ | 霊長類網膜色素上皮細胞特異的プロモーターＳｙｎＰ６１ |
| CN111542611A (zh) | 2017-11-30 | 2020-08-14 | 弗里德里克·米谢尔生物医学研究所 | 用于使基因在视网膜色素上皮中特异性表达的启动子SynPIII |
| JP2022505517A (ja) | 2018-10-25 | 2022-01-14 | フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ | 網膜神経節細胞中の遺伝子の特異的発現のためのプロモーターＳｙｎＰ１５１（ＰｒｏＣ２９） |
| JP2022505516A (ja) | 2018-10-25 | 2022-01-14 | フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ | 網膜神経節細胞中の遺伝子の特異的発現のためのプロモーターＳｙｎＰ１７（ＰｒｏＢ１） |
| JP2022512784A (ja) | 2018-10-25 | 2022-02-07 | フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ | 網膜神経節細胞中の遺伝子の特異的発現のためのプロモーターＳｙｎＰ７８（ＰｒｏＡ２７） |
| US20210388385A1 (en) | 2018-10-25 | 2021-12-16 | Friedrich Miescher Institute For Biomedical Research | Synp27 (prob12), a promoter for the specific expression of genes in protoplasmic astrocytes |
| WO2020084542A1 (en) | 2018-10-25 | 2020-04-30 | Friedrich Miescher Institute For Biomedical Research | Synp194 (prob15), a promoter for the specific expression of genes in retinal ganglion cells |
| WO2020084539A1 (en) | 2018-10-25 | 2020-04-30 | Friedrich Miescher Institute For Biomedical Research | Synp57 (proa14), a promoter for the specific expression of genes in photoreceptors |
| WO2020152626A1 (en) | 2019-01-24 | 2020-07-30 | Friedrich Miescher Institute For Biomedical Research | Synp166 (proa36), a promoter for the specific expression of genes in photoreceptors |
| EP3914299A1 (en) | 2019-01-24 | 2021-12-01 | Friedrich Miescher Institute for Biomedical Research | Synp5 (proa9), a promoter for the specific expression of genes in retinal ganglion cells |
| EP3914300A1 (en) | 2019-01-24 | 2021-12-01 | Friedrich Miescher Institute for Biomedical Research | Synp66 (proa21), a promoter for the specific expression of genes in retinal ganglion cells |
| EP3914721A1 (en) | 2019-01-24 | 2021-12-01 | Friedrich Miescher Institute for Biomedical Research | Synp35 (proc8), a promoter for the specific expression of genes in retinal ganglion cells |
| US20220154211A1 (en) | 2019-02-25 | 2022-05-19 | Novartis Ag | Compositions and methods to treat bietti crystalline dystrophy |
| MX2021010149A (es) | 2019-02-25 | 2021-09-14 | Novartis Ag | Composiciones y metodos para tratar la distrofia cristalina de bietti. |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024225830A1 (ko) * | 2023-04-27 | 2024-10-31 | 한국생명공학연구원 | 유전자의 망막 세포 내 발현을 위한 프로모터 및 이를 포함하는 벡터 시스템 |
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| PH12020550748A1 (en) | 2021-04-26 |
| SG11202005024QA (en) | 2020-06-29 |
| CA3083682A1 (en) | 2019-06-06 |
| BR112020010928A2 (pt) | 2020-11-24 |
| EP3717651A1 (en) | 2020-10-07 |
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| CN111542611A (zh) | 2020-08-14 |
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| RU2020121408A3 (enExample) | 2022-02-04 |
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| JP2021503934A (ja) | 2021-02-15 |
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| US20210010024A1 (en) | 2021-01-14 |
| MX2020005649A (es) | 2020-10-12 |
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