KR20200083512A - 수술 중의 외과적 마진 평가를 위한 이미징 방법 및 시스템 - Google Patents

수술 중의 외과적 마진 평가를 위한 이미징 방법 및 시스템 Download PDF

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KR20200083512A
KR20200083512A KR1020207015037A KR20207015037A KR20200083512A KR 20200083512 A KR20200083512 A KR 20200083512A KR 1020207015037 A KR1020207015037 A KR 1020207015037A KR 20207015037 A KR20207015037 A KR 20207015037A KR 20200083512 A KR20200083512 A KR 20200083512A
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image
target anatomy
fov
collapsed
fluorescence
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Korean (ko)
Inventor
메이 에스티. 존
조지 사디크
자카리 테일러
워렌 그런드페스트
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더 리전츠 오브 더 유니버시티 오브 캘리포니아
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Publication of KR20200083512A publication Critical patent/KR20200083512A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077Devices for viewing the surface of the body, e.g. camera, magnifying lens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/444Evaluating skin marks, e.g. mole, nevi, tumour, scar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4866Evaluating metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4887Locating particular structures in or on the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3904Markers, e.g. radio-opaque or breast lesions markers specially adapted for marking specified tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3937Visible markers
    • A61B2090/3941Photoluminescent markers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2505/00Evaluating, monitoring or diagnosing in the context of a particular type of medical care
    • A61B2505/05Surgical care
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02Operational features
    • A61B2560/0223Operational features of calibration, e.g. protocols for calibrating sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0233Special features of optical sensors or probes classified in A61B5/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04Arrangements of multiple sensors of the same type
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6408Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Theoretical Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Dermatology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Obesity (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020207015037A 2017-11-01 2018-11-01 수술 중의 외과적 마진 평가를 위한 이미징 방법 및 시스템 Ceased KR20200083512A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762580383P 2017-11-01 2017-11-01
US62/580,383 2017-11-01
PCT/US2018/058806 WO2019089998A1 (en) 2017-11-01 2018-11-01 Imaging method and system for intraoperative surgical margin assessment

Publications (1)

Publication Number Publication Date
KR20200083512A true KR20200083512A (ko) 2020-07-08

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KR1020207015037A Ceased KR20200083512A (ko) 2017-11-01 2018-11-01 수술 중의 외과적 마진 평가를 위한 이미징 방법 및 시스템

Country Status (6)

Country Link
US (1) US20200323431A1 (OSRAM)
EP (1) EP3704482A4 (OSRAM)
JP (1) JP7221285B2 (OSRAM)
KR (1) KR20200083512A (OSRAM)
CN (1) CN111433603B (OSRAM)
WO (1) WO2019089998A1 (OSRAM)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL265763B2 (en) 2016-10-04 2023-04-01 Univ California Multi-frequency harmonic acoustics for target identification and boundary detection
JP7313595B2 (ja) * 2019-06-03 2023-07-25 メルノヴァ プロプライエタリー リミテッド Mri後処理システムと方法
US12369797B2 (en) * 2019-08-20 2025-07-29 Intuitive Surgical Operations, Inc. Systems and a method for directing an imaging device to detect fluorescence and for determining a lifetime of the fluorescence
EP4135612A4 (en) 2020-04-14 2024-04-10 The Regents Of The University Of California METHOD AND SYSTEM FOR SELECTIVE SPECTRAL ILLUMINATION FOR OPTICAL IMAGE-GUIDED SURGERY
US20230218154A1 (en) * 2020-04-29 2023-07-13 The Regents Of The University Of California System and Method for Dynamic Optical Contrast Imaging
WO2024060018A1 (en) * 2022-09-20 2024-03-28 Juan Liu Non-invasive method for detection, visualization and/or quantification of an endogenous fluorophore such as melanin in a biological tissue

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5467767A (en) * 1991-11-25 1995-11-21 Alfano; Robert R. Method for determining if tissue is malignant as opposed to non-malignant using time-resolved fluorescence spectroscopy
US8068898B2 (en) * 2001-03-01 2011-11-29 Trustees Of Dartmouth College Fluorescence lifetime spectrometer (FLS) and methods of detecting diseased tissues
CN100477734C (zh) * 2001-07-06 2009-04-08 帕朗特研究公司 成像系统以及采用倒易空间光学设计的方法
US7116437B2 (en) * 2001-09-14 2006-10-03 Dmetrix Inc. Inter-objective baffle system
US20120302892A1 (en) * 2005-07-25 2012-11-29 Niyom Lue Portable optical fiber probe-based spectroscopic scanner for rapid cancer diagnosis
WO2010009106A1 (en) * 2008-07-14 2010-01-21 Bourke Frederic A Jr Advanced methods and systems for treating cell proliferation disorders
JP5415805B2 (ja) * 2009-03-31 2014-02-12 オリンパスメディカルシステムズ株式会社 診断支援装置
CN105907634B (zh) * 2010-01-20 2018-09-07 Emd密理博公司 细胞图像捕捉和远程监控方法
EP2820398B1 (en) * 2012-03-02 2018-10-24 The Regents of The University of California Apparatus for time-resolved fluorescence imaging and pulse shaping
GB201205607D0 (en) * 2012-03-29 2012-05-16 Ltd Technopath Distrib A fluorescence microtitre plate reader
WO2015154094A1 (en) * 2014-04-05 2015-10-08 Zand Jason M Apparatus, systems, and methods for mapping of tissue oxygenation
US10712272B2 (en) * 2016-09-27 2020-07-14 Trustees Of Tufts College System and method for assessing cellular metabolic activity

Also Published As

Publication number Publication date
WO2019089998A1 (en) 2019-05-09
EP3704482A4 (en) 2021-08-18
CN111433603A (zh) 2020-07-17
CN111433603B (zh) 2022-08-02
EP3704482A1 (en) 2020-09-09
JP7221285B2 (ja) 2023-02-13
US20200323431A1 (en) 2020-10-15
JP2021501883A (ja) 2021-01-21

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