KR20200070341A - 항-cd47 및 항-pd-l1로 난소암의 치료 - Google Patents
항-cd47 및 항-pd-l1로 난소암의 치료 Download PDFInfo
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- KR20200070341A KR20200070341A KR1020207014146A KR20207014146A KR20200070341A KR 20200070341 A KR20200070341 A KR 20200070341A KR 1020207014146 A KR1020207014146 A KR 1020207014146A KR 20207014146 A KR20207014146 A KR 20207014146A KR 20200070341 A KR20200070341 A KR 20200070341A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- General Chemical & Material Sciences (AREA)
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- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762574073P | 2017-10-18 | 2017-10-18 | |
| US62/574,073 | 2017-10-18 | ||
| PCT/US2018/056442 WO2019079549A1 (en) | 2017-10-18 | 2018-10-18 | TREATMENT OF OVARY CANCER BY ANTI-CD47 AND ANTI-PD-L1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20200070341A true KR20200070341A (ko) | 2020-06-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020207014146A Ceased KR20200070341A (ko) | 2017-10-18 | 2018-10-18 | 항-cd47 및 항-pd-l1로 난소암의 치료 |
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|---|---|
| US (1) | US20210047416A1 (enExample) |
| EP (2) | EP4194470A1 (enExample) |
| JP (3) | JP7308190B2 (enExample) |
| KR (1) | KR20200070341A (enExample) |
| CN (1) | CN111315783A (enExample) |
| AU (1) | AU2018351007B2 (enExample) |
| CA (1) | CA3078430A1 (enExample) |
| ES (1) | ES2938652T3 (enExample) |
| PL (1) | PL3697819T3 (enExample) |
| PT (1) | PT3697819T (enExample) |
| SI (1) | SI3697819T1 (enExample) |
| WO (1) | WO2019079549A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114716552B (zh) | 2016-01-11 | 2024-05-24 | 四十七公司 | 人源化、小鼠或嵌合抗cd47单克隆抗体 |
| CN111247172B (zh) | 2017-10-18 | 2023-11-14 | 四十七公司 | 基于抗cd47剂的卵巢癌疗法 |
| EP4129336B1 (en) | 2018-02-12 | 2025-05-07 | Forty Seven, LLC | Anti-cd47 agent-based treatment of cd20-positive cancer |
| EP3969484A4 (en) * | 2019-05-17 | 2023-07-05 | Nanjing GenScript Biotech Co., Ltd. | ANTI-CD47/ANTI-PD-L1 MULTIPLE ANTIGEN BINDING PROTEINS AND METHODS OF USE |
| US11702474B2 (en) | 2019-12-17 | 2023-07-18 | Pfizer Inc. | Antibodies specific for CD47, PD-L1, and uses thereof |
| CN120437288A (zh) * | 2019-12-24 | 2025-08-08 | 正大天晴药业集团南京顺欣制药有限公司 | 治疗卵巢癌的药物组合 |
| WO2021170082A1 (zh) * | 2020-02-28 | 2021-09-02 | 南京圣和药业股份有限公司 | 抗cd47/抗pd-l1抗体及其应用 |
| CN116670289A (zh) * | 2021-01-08 | 2023-08-29 | 北京韩美药品有限公司 | 抗pd-l1/抗cd47天然抗体结构样异源二聚体形式双特异抗体及其制备 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2616010T3 (es) | 2010-05-14 | 2017-06-09 | The Board Of Trustees Of The Leland Stanford Junior University | Anticuerpos monoclonales humanizados y quiméricos a CD47 |
| AU2014238105B2 (en) | 2013-03-15 | 2018-11-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for achieving therapeutically effective doses of anti-CD47 agents |
| CA2961774C (en) * | 2014-10-07 | 2023-05-23 | Immunomedics, Inc. | Neoadjuvant use of antibody-drug conjugates |
| TWI595006B (zh) * | 2014-12-09 | 2017-08-11 | 禮納特神經系統科學公司 | 抗ｐｄ－１抗體類和使用彼等之方法 |
| WO2017019767A1 (en) * | 2015-07-27 | 2017-02-02 | Myosotis, Llc | Inhibition of CXCL12 in Cancer Immunotherapy |
| CA2998644A1 (en) * | 2015-09-18 | 2017-03-23 | Arch Oncology, Inc. | Therapeutic cd47 antibodies |
| US20190290759A1 (en) * | 2015-12-28 | 2019-09-26 | Syndax Pharmaceuticals, Inc. | Combination of hdac inhibitor and anti-pd-l1 antibody for treatment of ovarian cancer |
| WO2017127707A1 (en) * | 2016-01-21 | 2017-07-27 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of cancer with combinations of immunoregulatory agents |
-
2018
- 2018-10-18 PL PL18807145.0T patent/PL3697819T3/pl unknown
- 2018-10-18 CN CN201880071877.6A patent/CN111315783A/zh active Pending
- 2018-10-18 US US16/756,790 patent/US20210047416A1/en not_active Abandoned
- 2018-10-18 AU AU2018351007A patent/AU2018351007B2/en active Active
- 2018-10-18 EP EP22207465.0A patent/EP4194470A1/en active Pending
- 2018-10-18 ES ES18807145T patent/ES2938652T3/es active Active
- 2018-10-18 JP JP2020521860A patent/JP7308190B2/ja active Active
- 2018-10-18 EP EP18807145.0A patent/EP3697819B1/en active Active
- 2018-10-18 SI SI201830820T patent/SI3697819T1/sl unknown
- 2018-10-18 CA CA3078430A patent/CA3078430A1/en active Pending
- 2018-10-18 PT PT188071450T patent/PT3697819T/pt unknown
- 2018-10-18 WO PCT/US2018/056442 patent/WO2019079549A1/en not_active Ceased
- 2018-10-18 KR KR1020207014146A patent/KR20200070341A/ko not_active Ceased
-
2022
- 2022-11-22 JP JP2022186496A patent/JP7474827B2/ja active Active
-
2024
- 2024-01-12 JP JP2024003136A patent/JP2024024121A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP7474827B2 (ja) | 2024-04-25 |
| PT3697819T (pt) | 2023-02-20 |
| ES2938652T3 (es) | 2023-04-13 |
| EP4194470A1 (en) | 2023-06-14 |
| JP2023014162A (ja) | 2023-01-26 |
| US20210047416A1 (en) | 2021-02-18 |
| EP3697819A1 (en) | 2020-08-26 |
| AU2018351007B2 (en) | 2024-05-16 |
| AU2018351007A1 (en) | 2020-05-21 |
| WO2019079549A1 (en) | 2019-04-25 |
| CN111315783A (zh) | 2020-06-19 |
| EP3697819B1 (en) | 2022-11-16 |
| SI3697819T1 (sl) | 2023-01-31 |
| JP2024024121A (ja) | 2024-02-21 |
| CA3078430A1 (en) | 2019-04-25 |
| JP7308190B2 (ja) | 2023-07-13 |
| PL3697819T3 (pl) | 2023-03-06 |
| JP2021500336A (ja) | 2021-01-07 |
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