KR20200039707A - 건강한 및 병든 심근세포의 성숙 상태를 향상시키기 위한 조성물 및 방법 - Google Patents

건강한 및 병든 심근세포의 성숙 상태를 향상시키기 위한 조성물 및 방법 Download PDF

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KR20200039707A
KR20200039707A KR1020207006161A KR20207006161A KR20200039707A KR 20200039707 A KR20200039707 A KR 20200039707A KR 1020207006161 A KR1020207006161 A KR 1020207006161A KR 20207006161 A KR20207006161 A KR 20207006161A KR 20200039707 A KR20200039707 A KR 20200039707A
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cardiomyocytes
derived
stem cell
cell
cells
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김덕호
제시 마카당당
알렉 에스.티. 스미스
한넬 루오홀라-베이커
제이슨 웨인 미클라스
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유니버시티 오브 워싱톤
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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KR1020207006161A 2017-08-16 2018-08-16 건강한 및 병든 심근세포의 성숙 상태를 향상시키기 위한 조성물 및 방법 Withdrawn KR20200039707A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762546438P 2017-08-16 2017-08-16
US62/546,438 2017-08-16
PCT/IB2018/056169 WO2019035032A2 (en) 2017-08-16 2018-08-16 COMPOSITIONS AND METHODS FOR ENHANCING THE MATURATION OF HEALTHY AND ILL HEART CARDIOMYCYTES

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US (1) US20200224168A1 (enExample)
EP (1) EP3664821A4 (enExample)
JP (1) JP2020535791A (enExample)
KR (1) KR20200039707A (enExample)
CN (1) CN111246863A (enExample)
WO (1) WO2019035032A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022010049A1 (ko) * 2020-07-09 2022-01-13 주식회사 티앤알바이오팹 인간 전분화능줄기세포 유래 심근세포를 이용한 SARS-CoV-2 바이러스 대상 후보 약물의 심근세포 독성 평가용 조성물 및 이를 이용한 심근세포 독성 평가 방법

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019113432A1 (en) * 2017-12-08 2019-06-13 University Of Washington Methods and compositions for detecting and promoting cardiolipin remodeling and cardiomyocyte maturation and related methods of treating mitochondrial dysfunction
EP3941496A4 (en) * 2019-03-18 2022-11-23 University of Washington METHODS OF PROMOTING CELLULAR MATURATION WITH AMPK ACTIVATORS
US12173322B2 (en) 2020-12-09 2024-12-24 The University Of Queensland Genome-edited induced pluripotent stem cells, and cells derived therefrom, and uses thereof
WO2023183371A2 (en) * 2022-03-22 2023-09-28 The Trustees Of Columbia University In The City Of New York Engineered heart tissue model of restrictive cardiomyopathy for drug discovery

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WO2014144219A1 (en) * 2013-03-15 2014-09-18 University Of Washington Through Its Center For Commercialization Device and methods comprising microelectrode arrays for electroconductive cells
WO2014201254A1 (en) * 2013-06-12 2014-12-18 University Of Washington Through Its Center For Commercialization Methods for maturing cardiomyocytes and uses thereof
US10844354B2 (en) * 2014-06-06 2020-11-24 Ncardia B.V. Cardiomyocyte maturation
CN106148284A (zh) * 2015-03-23 2016-11-23 苏州博瑞斯坦生物医药有限公司 小分子定向组织和器官再生的多能人类干细胞技术、方法和产品

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022010049A1 (ko) * 2020-07-09 2022-01-13 주식회사 티앤알바이오팹 인간 전분화능줄기세포 유래 심근세포를 이용한 SARS-CoV-2 바이러스 대상 후보 약물의 심근세포 독성 평가용 조성물 및 이를 이용한 심근세포 독성 평가 방법

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CN111246863A (zh) 2020-06-05
EP3664821A4 (en) 2021-06-09
WO2019035032A3 (en) 2019-04-25
US20200224168A1 (en) 2020-07-16
JP2020535791A (ja) 2020-12-10
EP3664821A2 (en) 2020-06-17
WO2019035032A2 (en) 2019-02-21

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