KR20190132769A - Experiment apparatus for experiment sample protuction and monitoring and experiment control system using this same - Google Patents

Abstract

Disclosed are an experimental device for experimental sample production and monitoring and an experiment control system using the experimental device. The experimental device for experimental sample production and monitoring comprises: a body unit having a plurality of sides of a polygonal shape, wherein the sides are formed as a plurality of coupling surfaces; a sample carrying unit including a rotary shaft vertically installed in the center of the body unit and installed on the body unit to be able to rotate, a rotary holder radially installed around the rotary shaft to hold a plurality of experimental containers at predetermined intervals along a circumference, and a rotary driving unit installed in the body unit to rotate the rotary shaft at a predetermined angle; a plurality of experimental functional units attached to and installed on the coupling surfaces to be detachable, respectively, to distribute a constant amount of sample to the experimental containers, mixing the samples distributed to the experimental containers, supplying energy by heat or light, or monitoring a state of the sample stored in the experimental containers; and a control unit installed in the body unit, controlling the functional units, and control the rotary driving unit.

Description

Experiment apparatus for experiment sample protuction and monitoring and experiment control system using this same}

The present invention relates to an experimental apparatus for manufacturing and monitoring an experimental sample and an experimental control system using the experimental apparatus, and more particularly, by connecting each modular experimental function unit for performing each experimental operation according to an experimental form, It can be experimented, the sample carrying unit installed in the main body part rotates the experiment container according to a preset program, and moves the position, and through the experimental function unit disposed on the moved experiment container for the sample accommodated in the experiment container The present invention relates to an experimental apparatus for producing and monitoring an experimental sample and to an experimental control system using the experimental apparatus, which enables the experiment operation to be performed more efficiently, as well as to facilitate the experimenter's safety.

In general, in the manufacture of chemicals or in vivo experiments, sample preparation requires a number of processes. Element technologies required for the sample preparation process include quantitative distribution of reagents, heat treatment, and light processing technology.

Quantitative dispensing technology is a technique for mixing and concentration of sample solution, which consists of a liquid channel through which various biochemicals can flow, and injects / supplys a desired volume into a desired container.

In the case of heat treatment or light treatment, it refers to a technology that supplies energy by heat or light to cause a specific reaction by a single material or a mixed solution.In the case of heat, detailed technology that controls conditions such as temperature, light intensity, wavelength, etc. need.

In addition, a monitoring technique is needed to check the status of the sample (material) being produced in the container to ensure that the sample is made well.

In general, there are techniques for confirming detailed structure through a magnified image through a microscope or change of state of a substance by using a fluorescent material, and various optical technologies such as absorbance and refractive index of a material are changed in real time according to the characteristics of a manufactured sample. It can be captured and utilized.

However, the time required to produce and monitor these samples is often over one day, and in the biotechnology sector, where cells are handled, samples are managed from six months to a year to see long-term changes. The same process as above should be performed repeatedly to optimize the experimental conditions, and a number of experiments are conducted to compensate for the errors in each experiment and the results are analyzed statistically.

In the event that an error occurs in all the experiments, there is a burden of re-creation from the beginning, and in the environment where the research results are obtained through the long time-consuming experiments and the repetitive work, the relevant researchers have spent most of the research period. There is a need to spend on making samples in the laboratory.

In-depth theoretical analysis and interpretation are also important, and for researchers, the process of experimenting close to simple labor is the biggest obstacle.

In addition, experimenters who directly handle biological samples that may cause toxic drugs or diseases are exposed to hazardous environments and conduct experiments using shields or protective equipment according to safety rules and regulations. The cases of damages have been ongoing, and the recent Foshan spill is a case where the danger has risen to the surface, requiring attention and support.

In the case of the existing experiment method, it was very difficult to implement all of the experiment equipment into one product, which has many additional functions in addition to the functions desired by the experiment equipment and a technology-driven product of a foreign company.

In addition, the existing experimental equipment performs only a single function, and when the need is exhausted, it loses its value and has a problem of low compatibility with various experiments.

In addition, the existing experimenters deal with harmful substances and biological samples, there was a risk of health through physical contact with the sample or inhalation in the air.

The present invention has been devised to solve the conventional problems as described above, and can be tested by connecting each of the modular experimental function unit for performing each experimental operation according to the experimental form, the sample carrying installed in the main body By rotating the additional experimental container according to a preset program, the experiment function is performed on the sample contained in the experimental container through the experimental function disposed on the moved experimental container. It is not only possible to proactively cope with various studies by designing the device, but also to reduce the burden and risk of the researcher so that safe and efficient research can be carried out. The purpose is to provide a control system.

Experimental apparatus for manufacturing and monitoring the experimental sample of the present invention for achieving the above object comprises a main body portion having a plurality of side surfaces having a plurality of sides to form a polygonal shape; A rotating shaft installed perpendicularly to the center of the main body part and rotatably installed on the main body part, a rotating support installed radially around the rotating shaft to mount a plurality of test containers at predetermined intervals along the circumference, and the main body; A sample carrying part installed at the part and configured to include a rotation driving part rotating the rotating shaft at a predetermined angle; It is detachably attached to the plurality of bonding surfaces, respectively, to distribute the quantitative sample to the lab vessel, mix the sample distributed to the lab vessel, supply energy by heat or light, or to the lab vessel. A plurality of experimental functions for monitoring the state of the sample received; And a control unit installed in the main body unit to control the plurality of functional units and to control the rotation driving unit.

The plurality of functional units may be configured to be spaced apart a predetermined interval on the circumference.

The plurality of experimental function unit is a dispensing function unit for injecting a predetermined amount of the sample to the experimental container; A heating function for applying heat to the sample accommodated in the test vessel; A mixing function unit for mixing the samples accommodated in the experimental container; A light irradiation function unit for irradiating light to a sample accommodated in the experiment container; A microscope function unit for obtaining an image by enlarging a sample accommodated in the test container; And a fluorescence measurement function unit for detecting a fluorescent substance contained in the sample accommodated in the experiment container, wherein, according to the driving of the rotation driving unit, the plurality of experiment containers rotate by a predetermined angle so that the plurality of experiment functions and the plurality of experiment containers are rotated. The experimental vessel of may be configured to be aligned one-to-one.

And a first terminal portion provided at each of the plurality of coupling surfaces, and a second terminal portion disposed at a lower end of the plurality of experimental functional portions, and attached to the plurality of coupling surfaces formed on the main body. In this case, the first terminal portion and the second terminal portion is configured to be connected to each other, the control unit is electrically connected to the plurality of functional units through the connection of the first terminal portion and the second terminal portion, power supply and function Control may be configured.

The sample carrier may be configured to rotate the experiment vessel at a predetermined position by time by driving the rotary driver by the controller.

The main body portion, the sample carrying portion, and the plurality of experimental functions may be installed in the sealed chamber so that the experiment can be made safely under the sealed condition.

On the other hand, the experimental control system using the experimental sample production and monitoring apparatus of the present invention is provided with a plurality of side surfaces forming a polygonal shape of the main body portion formed with a plurality of coupling surfaces, the perpendicular to the center of the main body portion A rotating shaft which is installed but rotatably installed on the main body, a rotating base that is radially installed around the rotating shaft to mount a plurality of test containers at predetermined intervals along a circumference, and is installed on the main body to provide the rotating shaft. A sample carrying unit configured to include a rotation driving unit rotating at a predetermined angle, and detachably attached to the plurality of coupling surfaces, respectively, to distribute a sample of the quantity to the experiment container, and to mix the sample distributed to the experiment container. To monitor the condition of the sample contained in the laboratory vessel, or to supply energy from heat or light. A sample device provided in a number of experimental function units and a main body unit, said sample unit being configured to control said plurality of functional units and control said rotational driving unit; The control unit is configured to enable wireless communication through a wireless communication network, and remotely controlling the plurality of experimental function units and the rotary drive unit, or set an experiment program for controlling the plurality of experimental function units and the rotary drive unit in the control unit. A user terminal; characterized in that it comprises a.

The apparatus may further include an information providing server configured to store and manage big data about the experimental result information and to provide the experimental result information to the control unit, wherein the control unit may include the big data about the experimental result information provided from the information providing server. Analyze to calculate the experimental optimal conditions for the experiment, and can be configured to control the plurality of experimental function and the rotation driving unit based on the calculated experimental optimum conditions.

According to the above, all the experiments are carried out by using the machine, which improves the reliability and accuracy of the experimental results, and minimizes the errors that occur during the experiment process, thereby reducing the part that the researcher must consider during the experiment. have.

In addition, it saves the effort and time that researchers have to devote to experiments, and enables not only simple repetitive work but also in-depth theoretical analysis. Since it can be assembled and used, there is an effect that the design and combination of the experimental equipment can be flexibly modified by easily coping with each other experiment.

In addition, the present invention is safe from the toxic reagents and harmful biological experiment environment can be safe experiments have the effect of ensuring a safe experimental environment of the researchers and the health of the body.

1 is a perspective view showing an experimental sample production and monitoring experimental apparatus according to an embodiment of the present invention,
Figure 2 is an exploded perspective view showing the separation of the experimental apparatus of Figure 1,
3 to 8 is a view showing a specific configuration of each experimental functional unit in the experimental apparatus shown in FIG.
9 is a control block diagram of an experimental sample production and monitoring apparatus according to an embodiment of the present invention,
10 is a view showing a closed chamber applied to the experimental sample production and monitoring experimental apparatus according to an embodiment of the present invention,
11 is a view showing an experimental control system using an experimental apparatus for manufacturing and monitoring an experimental sample according to an embodiment of the present invention.

Objects, other objects, features and advantages of the present invention will be readily understood through the following preferred embodiments associated with the accompanying drawings. However, the present invention is not limited to the embodiments described herein and may be embodied in other forms. Rather, the embodiments introduced herein are provided so that the disclosure may be made thorough and complete, and to fully convey the spirit of the present invention to those skilled in the art.

In the present specification, when a component is mentioned to be on another component, it means that it may be formed directly on the other component or a third component may be interposed therebetween. In addition, in the drawings, the thickness of the components are exaggerated for the effective description of the technical content.

Embodiments described herein will be described with reference to cross-sectional views and / or plan views, which are ideal exemplary views of the present invention. In the drawings, the thicknesses of films and regions are exaggerated for effective explanation of technical content. Therefore, the shape of the exemplary diagram may be modified by manufacturing techniques and / or tolerances. Therefore, the embodiments of the present invention are not limited to the specific forms shown, but also include changes in forms generated according to manufacturing processes. For example, the etched regions shown at right angles may be rounded or have a predetermined curvature. Thus, the regions illustrated in the figures have properties, and the shape of the regions illustrated in the figures is intended to illustrate a particular type of region of the device and is not intended to limit the scope of the invention. Although terms such as first and second are used to describe various components in various embodiments of the present specification, these components should not be limited by these terms. These terms are only used to distinguish one component from another. The embodiments described and illustrated herein also include complementary embodiments thereof.

The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. In this specification, the singular also includes the plural unless specifically stated otherwise in the phrase. As used herein, the words 'comprises' and / or 'comprising' do not exclude the presence or addition of one or more other components.

In describing the following specific embodiments, various specific details are set forth in order to explain and understand the invention in more detail. However, one of ordinary skill in the art can understand that the present invention can be used without these various specific details. In some cases, it is mentioned in advance that parts of the invention that are commonly known in the present invention and that are not highly related to the invention are not described in order to prevent confusion in explaining the present invention without cause.

Hereinafter, referring to FIGS. 1 and 2, an experimental apparatus 100 for manufacturing and monitoring an experimental sample according to an embodiment of the present disclosure will be described.

Experiment apparatus 100 for manufacturing and monitoring the sample of the present invention is configured to include a main body 101, a sample carrier 110, a plurality of experimental functional units (120a, 120b, 120c, 120d, 120e, 120f) do.

The main body portion 101 includes a plurality of side surfaces forming a polygon, and is formed as a coupling surface 103 to which a plurality of functional portions 120 are attached to the plurality of side surfaces.

In the present invention, the main body 101 has a hexagonal shape, and has a structure in which six coupling surfaces 103 are formed. However, the present invention is not limited thereto, and the main body 101 may be formed in various polygonal shapes such as a triangle, a square, a pentagon, a octagon, an octagon, and the number of coupling surfaces 103 may be determined according to the shape of the polygon.

The sample carrying unit 110 is installed to be rotated on the main body 101 and is equipped with an experimental container made of six glass bottles (vials), etc., to rotate the position of the experimental container.

The sample carrying unit 110 is configured to include a rotating shaft 112, the rotation support base (115, 118), the rotation driving unit (m).

The rotating shaft 112 is installed to be rotatable perpendicularly to the center of the main body portion 101, and six first arm portions 114 are radially extended on the lower outer circumferential surface at equal intervals.

In addition, six second arm portions 117 are radially formed on the upper outer circumferential surface of the rotation shaft 112 at equal intervals, and the second arm portions 117 are positioned at the same position in the vertical direction of the first arm portion 114. It is arranged to be located.

Rotating bases (115, 118) is configured to include a seating portion 115 and the insertion ring 118, the seating portion 115 is in a cylindrical shape of the top is open so that the lower portion of the experimental container (g) can be mounted and mounted. It is made, and is formed at the end of the first arm 114.

Insertion ring 118 is formed in the end of the second arm 114 is formed in a ring shape so that the experimental container (g) can be inserted.

In the present invention, the seating portion 115 and the insertion ring 118 is composed of six, respectively, is installed evenly around the rotation shaft 112, it is configured to be inserted into the six experimental containers (g), respectively. . In the present invention, the experimental container (g) is placed so that the lower end is supported by the seating portion 115, the upper portion is fitted to the insertion ring 118, it can be mounted on the rotating support base (115, 118) more stably.

The rotary drive unit (m) is made of an electric motor, is installed in the main body 101, is connected to the rotary shaft 112 through the power transmission means 119 is configured to rotate the rotary shaft 112. The power transmission means 119 may include a first bevel gear 119a installed on the rotation shaft 112 and a second bevel gear 119b installed on the drive shaft of the rotation driving unit m, and the first bevel gear 119a. And the second bevel gear 119b are configured to be geared to each other.

Therefore, according to the driving of the rotation driving unit m, the rotational force is transmitted to the rotation shaft 112 through the power transmission means 119, the rotation shaft 112 may be configured to rotate.

The power transmission means 119 has been described as being a bevel gear connection method, but if it is configured to transmit the rotational force of the rotation driving unit (m) to the rotating shaft 112, it may be composed of other known power transmission member.

In the present invention, the control unit 190 may be installed in the main body unit 101, and the rotation driving unit m may be configured to be controlled by the control unit 190. Therefore, the rotation transport unit 110 of the present invention can be configured to control the operation by the controller 190.

The controller 190 may rotate the rotation shaft 112 at intervals of 60 degrees by driving the rotation driving unit (m), whereby the positions of the six experimental containers (g) mounted on the rotation bases (115, 118) is 60 Can be rotated in degrees.

The plurality of experimental function units 120a, 120b, 120c, 120d, 120e, and 120f are configured to be attached to each coupling surface 103 of the main body 101 and detachably assembled.

At this time, each experimental function unit (120a, 120b, 120c, 120d, 120e, 120f) and the engaging surface 103 may be configured to be detachable by a magnetic force.

Meanwhile, in the present invention, each coupling surface 103 is provided with a first terminal portion 104, and inside the lower end of each of the functional portions 120a, 120b, 120c, 120d, 120e, and 120f to the first terminal portion 104. A second terminal portion 124 connectable is provided.

When the experimental function units 120a, 120b, 120c, 120d, 120e, and 120f are attached to the mating surfaces 103, the first terminal 104 and the second terminal 124 are configured to be connected. In the present invention, the first terminal part 104 and the second terminal part 124 electrically connect the control unit 190 installed in the main body part 101 and the respective functional parts 120a, 120b, 120c, 120d, 120e, and 120f. Thus, it may be configured to function as a terminal for power supply and control for each of the functional units 120a, 120b, 120c, 120d, 120e, and 120f.

A plurality of experimental function unit (120a, 120b, 120c, 120d, 120e, 120f) is installed so as to be arranged at intervals of 60 degrees on the edge of the main body portion 101, and dispenses a sample of the quantity set in the experimental container at the corresponding position It may be configured to mix the sample dispensed in the experiment vessel, supply energy by heat or light, and individually monitor the state of the sample contained in the experiment vessel g.

In the present invention, since the plurality of experimental functional units 120a, 120b, 120c, 120d, 120e, and 120f are modules that can be detachably coupled to the main body unit 101, the experimental functional units required according to the form of the experiment. Only may be selectively used in conjunction with the body portion 101. That is, all six experimental function units 120a, 120b, 120c, 120d, 120e, and 120f may all be used in combination with the main body unit 101, and only necessary experimental function units are required according to the experimental form such as the purpose of the experiment. Of course, less than six experimental functions can be used in combination with the main body 101.

According to the present invention, according to the shape of the main body unit 101, the experimental function unit for the polygon of the main body unit 101 can be configured only as much as the polygon variable. That is, when the main body portion 101 is made of a hexagon, up to six experimental function portions may be configured. When the main body portion 101 is a quadrangle, up to four experimental function portions may be formed, and the main body portion ( When 101) is octagonal, up to eight experimental functions can be configured.

On the other hand, the plurality of experimental function unit 120a, 120b, 120c, 120d, 120e, 120f of the present invention is a dispensing function unit (120a), the experimental container for injecting and distributing a predetermined amount of sample in the experimental container (g) Mixing function 120b for mixing the sample contained in (g), heating function 120c for applying heat to the sample contained in the experimental container (g), light irradiation for irradiating light to the sample contained in the experimental container (g) Microscope function 120e for acquiring an image by enlarging the sample housed in the functional unit 120d, the experiment container g, and a fluorescence measurement function unit 120f for detecting the fluorescent substance contained in the sample housed in the experiment container g. It is configured to include).

Each experimental function unit (120a, 120b, 120c, 120d, 120e, 120f) is attached to each engaging surface 103 of the main body 101, the vertical frame 121 is installed vertically upward, and the vertical frame ( The shandong block 122 is installed to be slidable up and down along the inner surface of the 121 and the elevating driving part 123 is installed in the vertical frame 121 to elevate the shandong block 122. It is configured to. Here, the elevating drive unit 123 is composed of a pneumatic cylinder, an electric cylinder, or a solenoid, and is installed in the vertical frame 123, and the expansion rod 123a of the vertical frame 121 is moved from the shanghai block 122. By being configured to be connected to the extended extension piece 122a, the shandong block 122 may be moved up and down along the vertical frame 121 according to the driving of the elevating driving part 123.

In addition, each experimental function unit (120a, 120b, 120c, 120d, 120e, 120f) has a vertical frame (for configuration of the experiment operation (sample distribution, mixing, heating, light irradiation, microscope, fluorescent material detection) 121) and the shanghai block 122.

1, 3, and 9, the dispensing function unit 120a is a solution storage unit (below the vertical frame 121) to discharge the sample solution for sample production to the experimental container (g) with a predetermined amount ( 132 is configured, the nozzle 131 is formed in the vertical movement block 122, the nozzle 131 and the solution storage unit 132 is connected by a connection hose 133, the fluid on the connection hose 133 The transfer pump p is configured to be installed. In this case, the fluid transfer pump p is configured to be controlled by the control of the controller 190.

According to the present invention, the controller 190 controls the driving of the fluid transfer pump p so that the sample solution stored in the solution storage 132 can be discharged through the nozzle 131 by a predetermined amount, and the nozzle 131 The sample solution discharged through) is injected into the experimental container (g) located below the nozzle 131 to be accommodated.

On the other hand, the controller 190 controls the driving of the lifting drive unit 123 so that the nozzle 131 is lowered to the inside of the experimental container (g) located on the lower side, as shown in Figure 3 (b), the fluid transfer pump (p) By discharging the sample solution by a predetermined amount through the nozzle 131, the experiment process of injecting the sample of the set capacity into the experimental container (g) can be made.

In addition, in the present invention, the dispensing function unit 120a is not limited to only discharging the sample solution stored in the solution storage unit 132 to the experimental container g, and the fluid transfer pump p is bidirectionally transferred. The pump of the type is applied, under the control of the controller 190, the fluid transfer pump (p) is driven to absorb the sample solution contained in the experimental container (g) through the nozzle 131 to the solution storage unit 132 It may be configured to perform a function of recovering or absorbing and storing.

1, 4, and 9, the mixing function unit 120b is configured such that a vibrator 141 made of an ultrasonic vibrator is installed in the shandong block 122, and the vibrator 141 is a control unit 190. It is configured to generate a vibration under the control of the controller 190 is connected to.

Reference numeral 143 denotes a wire electrically connecting the second terminal 124 and the vibrator 141, and serves as a cable for power supply or control signal transmission between the vibrator 141 and the controller 190. .

As shown in (b) of FIG. 4, the controller 190 controls the driving of the lift driver 123 so that the end of the vibrator 141 descends and is immersed in the sample accommodated in the test container g, and then the vibrator 141. It can be configured to drive the experimental process of applying vibration to the sample accommodated in the experimental container (g).

On the other hand, in the present invention, the vibrator 141 may be made of an ultrasonic vibrator as described above, of course, may be composed of other known vibrators.

1, 5, and 9, the heating function unit 120c is configured such that the heater 151 is installed in the shandong block 122, and the heater 151 is connected to the controller 190. It is configured to generate heat by receiving power from the controller 190.

As shown in FIG. 5B, the controller 190 controls the driving of the lift driver 123 so that the end of the heater 151 descends and is immersed in the sample accommodated in the test container g, and then the heater 151. It can be configured to drive the experimental process of applying heat to the sample contained in the experimental container (g) by driving.

On the other hand, the present invention may be configured so that the heater 151 is immersed in the sample accommodated in the experimental container (g) to pass the heat directly to the sample to meet the experimental temperature conditions of the sample, not limited to this, as shown in FIG. The heater 155 may be embedded in the unit 115, and the heater 155 may be configured to perform a sample heating experiment by indirectly transferring heat to the sample by applying heat to the experimental container g.

Reference numeral 153 denotes a wire electrically connecting the second terminal 124 and the heater 151 and functions as a cable for power supply and control signal transmission between the heater 151 and the controller 190. .

1, 6, and 9, the light irradiation function unit 120d is configured such that a light source 161 made of a led, a lamp, or the like is installed in the shandong block 122, and the light source 161 is provided. It is connected to the control unit 190 and configured to emit light by receiving power from the control unit 190.

As shown in FIG. 6B, the controller 190 controls the driving of the lift driver 123 so that the light source 161 descends and approaches the experiment container g, and then drives the light source 161. It can be configured to perform an experimental process of irradiating a specific light to the sample contained in the experimental container (g).

In the present invention, the light source 161 may be configured to irradiate various lights such as ultraviolet rays, infrared rays, and monochromatic light. Accordingly, the light source 161 is configured to irradiate specific light to the sample of the experimental container g under the control of the controller 190. Can be.

Reference numeral 163 denotes an electric wire electrically connecting the second terminal 124 and the light source 161, and serves as a cable for power supply and signal transmission between the light source 161 and the controller 190.

1, 7 and 9, the microscope function unit 120e is configured such that the photographing unit 171 made of a camera is installed in the shandong block 122, and the photographing unit 171 is a control unit ( Is connected to the 190 is supplied with power from the control unit 190, the photographing unit 171 is configured to transmit a photographed image or image to the control unit 190 by taking a magnified image of the sample contained in the experimental container (g) located on the lower side do.

As shown in FIG. 7B, the controller 190 controls the driving of the lift driver 123 so that the photographing unit 171 descends and approaches the sample accommodated in the experiment container g, and then the photographing unit 171. It can be configured to perform a monitoring experiment to obtain and store the image for the sample accommodated in the experimental container (g) by operating.

Reference numeral 173 denotes a wire electrically connecting the second terminal 124 and the photographing unit 171, and serves as a cable for power supply or signal transmission between the photographing unit 171 and the controller 190. do.

1, 8, and 9, the fluorescence measurement unit 120e includes a fluorescent material detection sensor 181 including a light emitting unit 181a and a light receiving unit 181b in the Shanghai East block 122. In addition, the fluorescent material detecting sensor 181 may be configured to be connected to the control unit 190 and controlled.

The controller 190 may emit light from the light emitting unit 181a to irradiate the sample accommodated in the experimental container g with light of a specific wavelength region. In this case, if the sample contains a fluorescent material, it emits fluorescence. The light receiver 181b detects the light fluorescing in the sample and transmits the light to the controller 190, and the controller 190 receives the amount of light detected by the light receiver 181b to calculate the amount of fluorescent material included in the sample. And store the calculated value.

As shown in FIG. 8B, the controller 190 controls the driving of the lift driver 123 so that the fluorescent material sensor 181 descends and approaches the sample contained in the test container g, and then detects the fluorescent material. The sensor 181 may be configured to detect whether the fluorescent substance contained in the sample contained in the test container g or the amount of the fluorescent substance is detected to perform a monitoring experiment process.

Reference numeral 183 denotes a wire electrically connecting the second terminal 124 and the fluorescent substance detection sensor 181, and a cable for power supply or signal transmission between the fluorescent substance detection sensor 181 and the controller 190. Function as.

In the present invention, the control unit 190 receives power from the power supply unit 192 to supply power to the configuration that requires the power of each of the experimental function unit (120a, 120b, 120c, 120d, 120e, 120f) and the sample carrier 110. Is configured to supply, in this case, the power supply unit 192 may be configured as commercial power or battery power.

In addition, in the present invention, the control unit 190 supplies power, control signals, and data communication to each of the experimental function units 120a, 120b, 120c, 120d, 120e, and 120f through the first terminal unit 104 and the second terminal unit 124. It is configured to be made, such as to select the required experimental function (120a, 120b, 120c, 120d, 120e, 120f) according to the experiment can be easily connected to the main body portion 101.

The control unit 190 is configured to control the sample carrying unit 110 according to a preset program so that the test vessel (g) mounted on the rotating support base 115 can be rotated at a predetermined angle to be moved. At this time, the position of the experimental container (g) means a position where each experimental operation of each experimental function unit (120a, 120b, 120c, 120d, 120e, 120f) is possible.

The controller 190 controls the sample carrying unit 110 so that a series of experiments can be carried out according to time by a preset program, and moves the experiment container g by rotational position for each time zone. It can be configured to drive the corresponding experimental function so that the corresponding experimental process can be performed.

For example, the controller 190 controls the sample carrier 110 to adjust the rotational position by rotating a predetermined angle such that the experimental container g is located below the nozzle 131 of the dispensing function 120a. The dispensing function unit 120a may be driven to distribute the sample solution in a predetermined amount through the nozzle 131 to the experimental container g.

Thus, in the state in which the sample solution of the quantitative distribution in the experimental container (g), the control unit 190 controls the sample carrying unit 110, the oscillator of the mixing function unit (120b) mixing the experimental container (g) in which the sample solution is distributed After adjusting the rotational position to be located at the lower side, the mixing function unit 120b may be driven to apply an oscillation to the sample accommodated in the experiment container g for a predetermined time to perform the mixing operation.

Subsequently, the controller 190 controls the sample carrier 110 to adjust the rotational position so that the experimental container g is positioned under the heater 151 of the heating function 120c, and then controls the heating function 120c. By driving the sample at a predetermined temperature to the sample of the experimental container (g) it can be made to the experiment process for the condition of the predetermined temperature.

Subsequently, the controller 190 controls the sample carrier 110 to adjust the rotational position so that the experiment container g is positioned under the light source 161 of the light irradiation function 120d, and then the light irradiation function 120d. ) Can be controlled to provide light energy to the sample of the test vessel (g) to make the experimental operation for light irradiation.

Thereafter, the controller 190 controls the sample carrier 110 to adjust the rotational position so that the experimental container g is positioned below the photographing unit 171 of the microscope function unit 120e, and then the The monitoring experiment process may be performed by acquiring a magnified image of the sample, and the control unit 190 controls the sample carrying unit 110 to control the experimental container g with the fluorescent material of the fluorescence measuring function unit 120f. After adjusting the rotational position to be located below the sensor 181, it is possible to perform a monitoring experiment to detect the presence or absence of the fluorescent material contained in the sample of the experimental container (g).

This series of experiments allows the experiment to be automatically performed according to a program previously stored in the controller 190. The experiments performed automatically result in more accurate and precise experiments while significantly reducing the effort and effort of the researchers. The reliability of the value can be greatly improved.

On the other hand, referring to Figure 10, the experimental apparatus for manufacturing and monitoring the experimental sample 100 of the present invention is installed in the closed chamber 108 is configured so that the safe experiment is made through the experimental apparatus 100 in a state blocked from the outside can do. At this time, the researchers can visually confirm the experimental sample through the window window 109 provided in the closed chamber 108.

As described above, the experimental sample production and monitoring apparatus 100 of the present invention is coupled to each side of the main body 101 according to the experimental form, each experimental function unit 120 performing each experiment operation, Since the experiment operation can be made to fit the experiment, compared to the experimental apparatus developed for the purpose of only one type of experiment as before, for various experiments, the researcher can easily configure each experimental function unit (120). ) By simply connecting the main body 101 to the main body 101 and inputting an experimental program to the control unit 190 to allow the corresponding experiment to be performed, thereby improving the compatibility of the experimental apparatus 100.

In addition, the experimental method, which previously depended on the efforts of the researchers, can be completely converted to the method performed automatically by the experimental apparatus, thereby improving the efficiency of the experiment and securing the experimental safety of the researcher.

Referring to FIG. 11, an experimental control system using an experimental apparatus for manufacturing and monitoring an experimental sample of the present invention is configured to include an experimental apparatus 100, a user terminal 200, and an information providing server 300 of the present invention.

The experiment apparatus 100 may be configured to be installed in the sealed chamber 108 to be cut off from the outside, as illustrated in FIG. 10, and the controller 190 of the experiment apparatus 100 may be connected to the external user terminal 200, Bluetooth, and Wi-Fi. It may be configured to communicate via a wireless communication network, such as, and can be configured to communicate with the external information providing server 300 and a wireless communication network.

The user terminal 200 may be implemented as a researcher's smart phone, tablet, computer, etc., the wireless communication with the controller 190, each experimental function unit 120a, 120b, 120c, 120d, 120e, 120f to the controller 190 ) And the sample carrier 110 may be configured to set an experimental program setting value for controlling the operation. In addition, the user terminal 200 receives from the control unit 190 the sample magnified image obtained through the microscope function unit 120e and the fluorescence measurement unit 120f or data information on the presence or absence of the fluorescent substance or the amount of the fluorescent substance. In addition, the received data can be displayed to allow the researcher to confirm monitoring information about the experiment.

In addition, the user terminal 200 of the present invention may be configured to directly control the operation of the experimental function unit (120a, 120b, 120c, 120d, 120e, 120f) and the sample carrier 110 by the researcher's operation. .

The information providing server 300 stores and manages big data about various experimental result information of scientific books, papers, and conference presentations, and provides the big data to the controller 190.

Here, the experimental result information may include the result data for various experiments, the magnified image of the sample, the presence or absence information of the fluorescent material for the sample, the amount of fluorescent material contained in the sample, and the like.

The controller 190 compares the experimental result information provided by the information providing server 300 with the experimental result information obtained from the experimental apparatus 100 to calculate an optimal experimental condition for sample production, and the calculated optimal experimental condition. Based on this, it can be configured to control the experimental function unit (120a, 120b, 120c, 120d, 120e, 120f) and the sample carrier (110).

For example, the controller 190 obtains the experimental result information while performing a sample production and monitoring experiment process through the experimental function unit (120a, 120b, 120c, 120d, 120e, 120f) and the sample carrier 110, Comparing and analyzing the experimental result information of the big data provided by the information providing server 300 by correcting the control of the control of the experimental function unit (120a, 120b, 120c, 120d, 120e, 120f) and the sample carrier (110) It can be configured to repeat the experiment so that the experiment can be made.

While the invention has been shown and described in connection with preferred embodiments for illustrating the principles of the invention, the invention is not limited to the configuration and operation as such is illustrated and described. Rather, it will be apparent to those skilled in the art that many changes and modifications can be made to the present invention without departing from the spirit and scope of the appended claims. Accordingly, all such suitable changes, modifications, and equivalents should be considered to be within the scope of the present invention.

101.Headquarters
110.Sample Carrier
112.Rotating shaft
114.The first arm
115 seating area
117 ... Second Arm
118 ... Insert ring
m ... rotary drive part
120.Experimental function
120a ... with dispensing function
120b ... with mixing function
120c ... with heating function
120d ... with light irradiation function
120e ... with microscope function
120 f ... with fluorescence measurement function
121 ... Vertical Frames
122 ... Up / Down Moving Block
123 ... Elevation Drive
131 ... Nozzle
141 ... vibrator
151 Heater
161 ... light source
171.Photographer
181 ... Fluorescent sensor

Claims (8)

A main body part having a plurality of side surfaces forming a polygonal shape and the plurality of side surfaces formed of a plurality of coupling surfaces;
A rotating shaft installed perpendicularly to the center of the main body part and rotatably installed on the main body part, a rotating support installed radially around the rotating shaft to mount a plurality of test containers at predetermined intervals along the circumference, and the main body; A sample carrying part installed at the part and configured to include a rotation driving part rotating the rotating shaft at a predetermined angle;
It is detachably attached to the plurality of bonding surfaces, respectively, to distribute the quantitative sample to the lab vessel, mix the sample distributed to the lab vessel, supply energy by heat or light, or to the lab vessel. A plurality of experimental functions for monitoring the state of the sample received; And
And a control unit installed in the main body and controlling the plurality of functional units and controlling the rotation driving unit.
The method of claim 1,
Experimental sample production and monitoring device, characterized in that the plurality of functional units are installed circumferentially spaced apart.
The method of claim 2,
The plurality of experimental function unit
A dispensing function unit for injecting a predetermined amount of sample into the test container;
A heating function for applying heat to the sample accommodated in the test vessel;
A mixing function unit for mixing the samples accommodated in the experimental container;
A light irradiation function unit for irradiating light to a sample accommodated in the experiment container;
A microscope function unit for obtaining an image by enlarging a sample accommodated in the test container;
It includes; and a fluorescence measurement function for detecting a fluorescent material contained in the sample accommodated in the experimental container;
In accordance with the driving of the rotary drive unit, the plurality of experimental vessels rotated by a predetermined angle, the experimental sample production and monitoring apparatus, characterized in that the plurality of experimental function unit and the plurality of experimental containers are configured to be aligned one-to-one.
The method of claim 3, wherein
Further comprising: a first terminal portion provided on each of the plurality of coupling surfaces, and a second terminal portion provided at the lower end of the plurality of experimental function portions,
When attaching the plurality of experimental function portions to the plurality of engaging surfaces formed on the body portion, the first terminal portion and the second terminal portion is configured to be connected to each other,
The control unit is electrically connected to the plurality of functional units through the connection of the first terminal unit and the second terminal unit, the experimental sample production and monitoring device, characterized in that configured to be a power supply and function control.
The method of claim 4, wherein
The sample carrier is experimental sample production and monitoring device, characterized in that configured to move the experiment vessel to the predetermined position in accordance with the time driven by the rotary drive unit by the control unit.
The method of claim 1,
Experimental sample production and monitoring apparatus, characterized in that the main body portion, the sample carrying portion, the plurality of the experimental function is configured to be installed in the closed chamber so that the experiment can be made safely in a sealed condition.
A main body portion having a plurality of side surfaces forming a polygonal shape and the plurality of side surfaces formed of a plurality of coupling surfaces;
A rotating shaft installed perpendicularly to the center of the main body part and rotatably installed on the main body part, a rotating support installed radially around the rotating shaft to mount a plurality of test containers at predetermined intervals along the circumference, and the main body; A sample carrying unit installed in the unit and configured to include a rotary driving unit rotating the rotary shaft at a predetermined angle;
It is detachably attached to the plurality of bonding surfaces, respectively, to distribute the quantitative sample to the lab vessel, mix the sample distributed to the lab vessel, supply energy by heat or light, or to the lab vessel. A plurality of experimental functions for monitoring the state of the sample received;
A sample device installed in the main body part, the sample device configured to include a control part controlling the plurality of functional parts and controlling the rotation driving part; And,
The control unit is configured to enable wireless communication through a wireless communication network, and remotely controlling the plurality of experimental function units and the rotary drive unit, or set an experiment program for controlling the plurality of experimental function units and the rotary drive unit in the control unit. Experimental control system using an experimental apparatus for producing and monitoring the experimental sample comprising a user terminal.
The method of claim 7, wherein
Big data for the experimental result information is stored and managed, and further comprising: an information providing server for providing the experimental result information to the controller;
The control unit analyzes the big data for the experimental result information provided from the information providing server, calculates an experimental optimal condition for the experiment, and controls the plurality of experimental function units and the rotation driving unit based on the calculated experimental optimal condition. Experimental control system using an experimental apparatus for producing and monitoring an experimental sample.

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