KR20190102611A - Device and Method for Measuring Skin changes due to Blue-light - Google Patents

Abstract

The present invention relates to a device and method for measuring a skin change due to blue light. According to one embodiment of the present invention, the device comprises: one or more light sources irradiating light in blue light bands with different amount of light to a plurality of test areas set on a skin area to be tested; and a control unit detecting the minimum darkening reaction point among the test areas and calculating the amount of light in the corresponding test area as the minimal pigment dose (MPD) for blue light.

Description

Device and method for measuring skin change due to blue light {Device and Method for Measuring Skin changes due to Blue-light}

The present invention relates to an apparatus and method for measuring skin change by blue light, and more specifically, to skin change by blue light, and furthermore, skin change by blue light that can measure the blocking power of a blue light blocker. It relates to a measuring device and a method.

Light exposure, such as sun exposure, is a very important factor in terms of beauty and health. Excessive light exposure can lead to cell transformation or skin cancer from UV radiation. Excessive light exposure causes problems such as decreased skin elasticity and skin spots, and has an important effect from a cosmetic point of view.

Among various lights, blue light is a short-wavelength high-energy visible light that is emitted from sunlight, LED lighting, TVs, computer monitors, and displays of smart devices, and is known to be harmful to the human body.

Blue light adversely affects the human body, such as dry eye, decreased vision, and decreased retinal function, and it also disturbs the human body's biological rhythm and causes sleep disturbances. Unlike sunlight emitted only during the daytime, blue light is exposed all day due to the lifestyle of modern people, so exposure to blue light is a very important factor in the health and beauty of modern people.

In order to measure the effect on such blue light, in vitro tests such as cell tests, spectral measurements and the like are known. In the case of Patent Document 1, the blue response of the skin caused by blue light is measured, and the amount of elastin material, ie, the degree of photodamage, caused by the blue response is disclosed.

Patent document 1 only measures whether a response substance is generated by blue light, and does not directly measure skin change generated by blue light. That is, the prior art does not measure skin changes such as pigmentation.

In addition, blocking products such as blue light blockers are being sold, but there is no method of measuring or evaluating the blocking force of such products. Thus, there is no way to show or demonstrate a substantial effect when such a product is applied to the skin.

US 7,558,416 B2

SUMMARY OF THE INVENTION The present invention has been made to solve the above problems, and an object of the present invention is to provide an apparatus and method for measuring skin change caused by blue light, which can measure skin change caused by blue light.

In addition, an object of the present invention is to provide an apparatus and method for measuring skin change caused by blue light, which can measure and evaluate the blocking power of a blocking product such as a blue light blocking agent.

The present invention also provides an apparatus and method for measuring skin change by blue light that can be measured by changing various factors such as light intensity, light amount, irradiation time, and the like of blue light.

According to an embodiment of the present invention, the apparatus for measuring skin change by blue light may include at least one light source for irradiating light of a blue light band with different amounts of light to a plurality of test areas set on a skin area to be tested; And a controller configured to detect a minimum blackening reaction point among the test areas and calculate a light amount of a corresponding test area as a minimum blackening amount (MPD) for blue light.

The controller may control the light intensity, the irradiation time, or both so that the light amount of the light source is at least two times the average ultraviolet light amount.

The light source may be configured to irradiate light in the 450 to 470 nm band.

The controller may calculate and compare the first minimum blackening amount MPD and the second minimum blackening amount MPD with respect to the test areas to which the blue light blocking product to be tested and the test areas to which the test targets are applied, respectively.

The blue light blocking product is a blue light blocking agent, and the blue light protection index (PB) of the blue light blocking agent may be calculated by [Equation 1].

[Equation 1]

In the method of measuring skin change by blue light according to an embodiment of the present invention, a plurality of test areas are set on a skin area to be tested, and the test areas are irradiated with light of a blue light band with different amounts of light. step; And detecting a minimum blackening reaction point among the test areas and calculating a light amount of a corresponding test area as a minimum blacking amount (MPD) for blue light.

The amount of light of the blue light may be adjusted by adjusting the light intensity or the irradiation time, or both, to be at least twice the average amount of ultraviolet light.

The blue light band may be a 450 to 470 nm band.

The minimum blackening reaction point is whether or not the contour of the test region is formed, whether the pigmentation occurs in a region over a predetermined area of the test region, or the melanin index before and after blue light irradiation is equal to or greater than a predetermined value or a predetermined ratio. It can be determined depending on whether or not it has changed.

Calculating a first minimum blackening amount MPD for test areas not to which the blue light blocking product to be tested is applied; And calculating a second minimum blackening amount MPD for the test areas to which the blue light blocking product is applied.

The skin region may be a skin region of type 3 or more of the Fitzpatrick skin type.

The blue light blocking product is a blue light blocking agent, and the blue light protection index (PB) of the blue light blocking agent may be calculated by [Equation 1].

[Equation 1]

According to an embodiment of the present invention, it is possible to provide an apparatus and method for measuring skin change by blue light that can measure and analyze the effect of blue light directly on the skin.

In addition, according to an embodiment of the present invention, by providing a skin change measurement apparatus and method for measuring the skin change by the blue light to measure and analyze the blocking force of the blue light blocking product such as a blue light blocker. can do.

Further, by changing and measuring various factors such as light intensity, light quantity, irradiation time, and the like of the blue light, it is possible to provide an apparatus and method for measuring skin change caused by blue light that can analyze the effects of the blue light in various ways.

1 is a view schematically showing an apparatus for measuring skin change by blue light according to an embodiment of the present invention.
2 is a view schematically showing a skin change measurement method by blue light according to an embodiment of the present invention.
3 is an image of test areas before and after blue light irradiation measured according to one embodiment of the invention.
FIG. 4 is a graph showing melanin index of test areas before and after blue light irradiation of FIG. 3.

The embodiments may be variously modified and have various embodiments, and specific embodiments will be described in detail with reference to the accompanying drawings. However, this is not intended to limit the scope to the specific embodiments, it should be understood to include all transformations, equivalents, and substitutes included in the scope of the disclosed spirit and technology. In describing the embodiments, when it is determined that the detailed description of the related known technology may obscure the gist, the detailed description thereof will be omitted.

In an embodiment, the module or unit performs at least one function or operation, and may be implemented in hardware or software, or in a combination of hardware and software. In addition, a plurality of modules or a plurality of units may be integrated into at least one module except for a module or a unit that needs to be implemented with specific hardware, and may be implemented as at least one processor (not shown). Can be.

Hereinafter, embodiments will be described in detail with reference to the accompanying drawings, and in the following description with reference to the accompanying drawings, the same or corresponding components will be given the same reference numerals and redundant description thereof will be omitted.

FIG. 1 schematically shows an apparatus for measuring skin change by blue light according to an embodiment of the present invention, wherein the apparatus for measuring skin change by blue light according to an embodiment is blue in a plurality of test areas with different amounts of light. One or more light sources 10 irradiating light in the light band, and the minimum blackening reaction point is detected among the test areas, and the light amount of the corresponding test area is calculated as a minimum pigment dose (MPD) for the blue light. It includes a control unit 20 to.

A plurality of test regions R1, R2, R3, R4, R5, R6, R7, and R8 are set on the skin region S to be measured for skin pigmentation by blue light. The skin area S may be various skin areas such as an arm, a leg, a face, a back, and a neck. Masks (not shown) are disposed in regions other than the plurality of test regions R1, R2, R3, R4, R5, R6, R7, and R8, so that blue light is irradiated only in the test region or other test regions. The blue light irradiated within can be prevented from affecting.

The light source 10 may be configured to radiate light of a blue light band to a plurality of test regions with different amounts of light. The amount of light can be expressed as shown in [Equation 2] below.

[Equation 2]

Light quantity (J / cm ² ) = light intensity × irradiation time

Each of the test regions R1, R2, R3, R4, R5, R6, so that the plurality of test regions R1, R2, R3, R4, R5, R6, R7, R8 are irradiated with blue light at different amounts of light. The light intensity irradiated on R7, R8) may be adjusted, the irradiation time may be adjusted, and both the light intensity and the irradiation time may be adjusted.

In order to control the light intensity irradiated to the respective test regions R1, R2, R3, R4, R5, R6, R7, R8, the respective test regions R1, R2, R3, R4, R5, R6, R7, Light sources 10 corresponding to R8) may be disposed.

That is, although one light source 10 is illustrated in the drawing, the present invention is not limited thereto. For example, a plurality of light sources, for example, may correspond to the respective test regions R1, R2, R3, R4, R5, R6, R7, and R8. It may also include a number of light sources 10.

In addition, the respective test areas R1, R2, R3, R4, R5, R6, R6, R6, R6, R6, R6, R6, R6, R6, R6, R6, R5, R6, R7 and R8) may further include a mask to block the blue light after a predetermined irradiation time.

Blue light refers to light rays having wavelengths in the approximately 400 to 495 nm band. On the other hand, ultraviolet light has a band of approximately 10 to 400 nm. Blue light has a long wavelength compared to ultraviolet light, so the amount of energy is low. Therefore, it is difficult to measure skin change characteristics in the same manner as ultraviolet rays.

Therefore, in order to supply an amount of energy capable of inducing an effective skin change, according to one embodiment of the present invention, the control unit 20, the light amount of the light source 10 is ² of approximately 27 J / cm ² which is the average amount of ultraviolet light It can be controlled to adjust the light intensity or irradiation time, or both to be more than doubled. Specifically, it can be controlled to have a light amount of approximately 55 J / cm ² or more. When the amount of light is less than 2 times, since the amount of energy decreases, it is difficult to derive an effective skin pigment change, and the error due to external influence may increase.

In addition, according to an embodiment of the present invention, the light source 10 may be configured to irradiate light in the light source of 450 to 470 nm band. Light below 450 nm contains wavelengths in the purple region, making it difficult to measure the influence of pure blue light, and light above 470 nm includes wavelengths in the green region, making it difficult to measure the influence of pure blue light as well. This is because it causes errors.

Although not necessarily limited thereto, a blue LED light source may be used as the light source 10.

In addition, according to an embodiment of the present disclosure, the controller 20 detects a minimum blackening reaction point among the test areas and calculates a light amount of a corresponding test area as a minimum blacking amount (MPD) for blue light.

Blue light is longer than UVA, so it can induce darkening of the skin. The controller 20 detects a blackening reaction point at which a blackening reaction is induced among the plurality of test regions R1, R2, R3, R4, R5, R6, R7, and R8, but minimum blackening in which the blackening reaction occurs at a minimum amount of light. Detect the reaction point.

In addition, in order to derive effective skin change for blue light, a subject having a skin type of 3 or more may be selected from the Fitzpatrick skin types (see Table 1 below) in which blackening reactions occur well when subjects are selected. When testing blockers such as blue light blockers, it can be helpful to easily derive effective skin changes to produce accurate results.

Fitzpatrick Skin Type Explanation One It burns easily and does not burn black. 2 Burn easily, burn a little black. 3 Burns moderately and burns gradually. 4 Hardly burns and burns gradually. 5 Little burns and rides extremely much. 6 It does not burn at all and burns very thickly.

FIG. 1 relates to an embodiment in which the amount of light is sequentially increased with respect to the plurality of test regions R1, R2, R3, R4, R5, R6, R7, and R8, in which case three test regions as shown in FIG. 1. A blackening reaction can be induced among (R6, R7, R8). Among the three test regions R6, R7, and R8, the test region R6 where the blackening reaction occurs with the minimum amount of light becomes the minimum blackening reaction point, and the amount of light in the test region R6 becomes the minimum amount of blackening MPD. .

According to an embodiment of the present invention, the effective skin change occurs by the blue light to calculate the minimum blackening amount (MPD) value, which is the amount of light for the test area, so that the skin change by the blue light on the target skin may be measured. . For example, the skin or skin region having a larger minimum blackening amount (MPD) may be a skin or skin region having low sensitivity due to blue light.

Meanwhile, according to one embodiment of the present invention, the blocking force or blocking effect of the blue light blocking product may be measured. Blue light is not only included in the visible light range of sunlight, but also emitted from LED lights, LED displays, smartphones, tablets, monitors, and the like, so that it is always exposed in daily life. Therefore, the information on the blocking power of the blue light blocker may be an important indicator when a consumer purchases or uses the blue light blocker.

According to one embodiment of the invention, the blue light blocking product can be analyzed by focusing on the blocking effect corresponding to how much the effect on the skin is substantially reduced.

To this end, the control unit 20 may be derived by comparing the minimum blackening amount of the test areas to which the blue light blocking product to be tested and the test areas not to be applied.

To this end, the control unit 20 may determine the first minimum blackening amount MPD and the second minimum blackening amount MPD for the test areas to which the blue light blocking product to be tested and the test areas not to be applied, respectively. It can be calculated and compared.

The blue light blocking product is a blue light blocking agent in a cosmetic form. In the case of the present invention, by providing a quantitatively the blocking power of the blue light blocker applied to the skin in numerical form, it can be applied to guide or prove the blue light blocking power of the product.

Specifically, the protection grade of Blue-light (PB) of the blue light blocker to be tested may be calculated by [Equation 1].

[Equation 1]

The blue light protection index (PB) as described above is an index indicating the blocking effect of the blue light blocker, the higher the index is an excellent blocking effect of the blue light blocker.

In other words, by measuring the ratio of the MPD of the skin with the blocker and the skin without the blocker, it can be shown how much the effect on the skin pigmentation actually blocked.

2 is a view schematically showing a skin change measurement method by blue light according to an embodiment of the present invention. The skin change measuring apparatus described above may be applied to a skin change measuring method. Therefore, the above-described information on the skin change measuring apparatus can be applied to the skin change measuring method. The opposite is also true.

Referring to FIG. 2, in the method of measuring skin change by blue light, a first step (S10) of irradiating light of a blue light band with different amounts of light to a plurality of test areas set on a skin area and the test area Among them, a second step (S20) of calculating the minimum amount of blackening reaction point of light as the minimum amount of blackening (MPD) for the blue light.

By setting the amount of light of the blue light source, it is possible to set such that different amounts of light are irradiated to the respective test areas. Since the unit of light amount, light intensity, and time of the blue light source is determined or unknown, the light intensity unit may be determined by W / cm ² , which is a unit of the detector, and then the light amount and time may be set.

Since the amount of light is determined by the light intensity and irradiation time as described in the skin change measuring device, the irradiation time is adjusted while irradiating the skin with the same light intensity blue light light, or the blue light light of different light intensity is the same. There are two ways to do it with irradiation time. Of course, you can also adjust the amount of light by adjusting both simultaneously.

The light amount of the blue light may be set differently from the upper limit value and the lower limit value according to the subject or the skin region. However, in order to derive an effective skin change, the light intensity or irradiation time, or both, can be adjusted so that the upper limit value and the lower limit value are both two times or more the average amount of ultraviolet light. Since blue light has lower energy than ultraviolet light, the amount of light needed to cause pigmentation of the skin can be set larger.

According to one embodiment, the blue light band may be a 450 to 470 nm band. This is to prevent the influence of the violet light or the green light, thereby preventing the error.

In addition, since blue light has a longer wavelength than UVA, in consideration of inducing a blackening reaction, the blue light may be selected as a type 3 or more of the Fitzpatrick skin type in which the blackening reaction occurs well. To induce a smooth pigmentation reaction.

The minimum blackening reaction point is a point where blackening reaction occurs and has a minimum amount of light, and the first blackening reaction point is whether the outline of the test area is clearly revealed, or whether the pigmentation occurs in an area over a predetermined area of the test area. It may be determined depending on whether the melanin index before or after the blue light irradiation has changed by more than a predetermined value or by more than a predetermined ratio.

More specifically, check whether the contour of the pigmentation reaction, the blackening reaction area is clear, check whether the pigmentation occurred at 2/3 or more points in the test area, or measure the melanin index by the instrument or more. You can identify test areas with differences.

In the case of the melanin index, the difference in the melanin index before and after irradiation of blue light can be detected to detect a test region where the first pigmentation occurred. Therefore, the minimum blackening amount can be confirmed by first detecting the point where the difference in the melanin index occurs as the minimum blackening reaction point. However, the present invention is not necessarily limited thereto, and a region where the blackening reaction cannot be visually confirmed may occur even when the melanin index is different. Therefore, a point where the difference between the melanin index is greater than or equal to a predetermined value or greater than or equal to a predetermined ratio is detected. By setting it as a blackening reaction point, the minimum blackening amount here can be confirmed.

In the same manner as above, the minimum blackening reaction point may be identified, and the amount of light at the minimum blackening reaction point may be derived to check the skin change by the blue light and the blocking effect of the blue light blocking product.

In addition, according to an embodiment of the present invention, in order to measure and confirm the blocking effect of the blue light blocking agent to be tested, the first step (S10) for the test areas that do not apply the blue light blocking product to be tested. And a second step S20 to calculate a first minimum blackening amount MPD, and perform the first step S10 and the second step S20 on test areas to which the blue light blocking product is applied. The second minimum blackening amount MPD can be calculated.

According to an embodiment, the second minimum blackening amount MPD may be calculated for the skin to which the blue light blocking product is applied at a light quantity of 2 to 4 times the first minimum blackening amount MPD.

According to the above method, by comparing the first and second minimum blackening amount (MPD) before and after applying the blue light blocking product, it is possible to confirm the blocking force or blocking effect of the blue light blocking product.

According to one embodiment, the blocking effect of the blue light blocker may be calculated by the blue light protection index (PB), it may be calculated by the following [Equation 1].

[Equation 1]

As such, the blocking effect of blue light blockers can be demonstrated based on skin changes to blue light while providing the difference in quantitative data.

In addition, the effects of blue light blockers can be directly evaluated and expressed. It can also be used as evidence for demonstrating the blocking power of blocking products.

According to various embodiments of the present disclosure, skin changes due to blue light may be observed by receiving different amounts of light for each skin region. Skin change measuring apparatus and method according to the present invention can be evaluated in vivo, it is possible to measure the effect of blue light directly on the skin change. That is, since the effect of blue light on the human body is measured by approaching from the viewpoint of pigmentation, the effect of blue light on the skin can be substantially demonstrated, measured, and compared.

In addition, since various factors affecting blue light measurement such as light intensity, light amount, irradiation time, and subject selection of blue light can be changed and set, it is possible to provide an apparatus and method for measuring skin change that can be analyzed in various aspects. .

In the light quantity setting method, the time may be adjusted by irradiating the skin with a blue light source having the same light intensity, or the blue light sources having different light intensity may be irradiated at the same time. These methods control the overall amount of light, which can measure skin pigmentation by blue light that is otherwise formed from the adjusted amount of light.

According to the prior art, there is insufficient evidence to confirm that the blue light blocker actually blocks the blue light, and it is difficult to provide information on how and how to prevent the blue light blocker. However, according to various embodiments of the present invention, it is possible to evaluate the effect of blue light on the skin and to prove the blocking effect of the blue light blocking product, in particular the blue light blocking agent, and provide quantitative information on the blocking power. have.

In addition, it can be used as data demonstrating the efficacy of blue light blocking products, and can be used to analyze various properties of blue light blocking agents.

Six test areas (T1, T2, T3, T4, T5, and T6) were irradiated by setting different amounts of light as shown in Table 2 below.

Test area Quantity of light Test area Quantity of light T1 5 J / cm ² T4 60 J / cm ² T2 10 J / cm ² T5 80 J / cm ² T3 30 J / cm ² T6 90 J / cm ²

The light quantity in the test region T1 was the lowest, and the light quantity was set to increase toward the test region T6 to induce blackening reactions at different light amounts in each test region.

The images of test areas before (a) and immediately after (b) irradiation of blue light were as shown in FIG. 3. Referring to FIG. 3, in the test areas T4, T5, and T6, the contours of each area were clearly revealed, and a blackening reaction appeared. Since the region having the minimum light amount among the test regions T4, T5, and T6 is the test region T4, it was confirmed that the minimum blackening amount MPD was 60 J / cm ² .

Six different test areas (T1, T2, T3, T4, T5, and T6) different from Example 1 were set and examined as shown in Table 2 above.

4 is a graph showing melanin indices measured before and after blue light irradiation for the test regions (T1, T2, T3, T4, T5, T6) of six Example 2. FIG.

Referring to FIG. 4, when the difference between the melanin index before and after the blue light irradiation of each test region was confirmed, the melanin index was increased from the test region T3 to quantitatively confirm that the pigmentation occurred.

In the test region T3, the melanin index increased by about 17% or more, and in the test region T4, the melanin index increased by about 30% or more. The melanin index change before and after blue light irradiation was confirmed to change the skin according to the amount of blue light. Increasing the melanin index can provide quantitative data on how much pigmentation occurs according to the amount of blue light, and can be used as a data for determining the minimum amount of blackening (MPD).

10: light source
20: control unit
R1, R2, R3, R4, R5, R6, R7, R8: Test Area
S: skin area

Claims (12)

Skin change measurement device by blue light,
At least one light source for irradiating blue light band with different amounts of light to a plurality of test areas set on the skin area to be tested; And
And a controller configured to detect a minimum blackening reaction point among the test areas and calculate a light amount of a corresponding test area as a minimum blacking amount (MPD) for the blue light.
The method of claim 1,
And the controller controls the light intensity, irradiation time, or both so as to control the amount of light of the light source to be at least two times the average amount of ultraviolet light.
The method of claim 1,
The light source is a device for measuring skin changes by blue light, characterized in that configured to irradiate light in the 450 to 470 nm band.
The method of claim 1,
The controller calculates and compares the first minimum blackening amount MPD and the second minimum blackening amount MPD with respect to the test areas to which the blue light blocking product to be tested and the applied test areas are applied, respectively. Skin change measuring device by blue light.
The method of claim 4, wherein
The blue light blocking product is a blue light blocking agent,
Blue light protection index (PB) of the blue light blocker is a skin change measurement device by blue light, characterized in that calculated by [Equation 1].
[Equation 1]

As a method of measuring skin change by blue light,
Setting a plurality of test areas on the skin area to be tested, and irradiating the test areas with light in a blue light band with different amounts of light; And
And detecting a minimum blackening reaction point among the test areas, and calculating a light amount of a corresponding test area as a minimum blacking amount (MPD) for the blue light.
The method of claim 6,
The light amount of the blue light is a skin change measurement method by the blue light, characterized in that the light intensity or the irradiation time, or both are adjusted to be at least twice the average ultraviolet light amount.
The method of claim 6,
The blue light band is a skin change measurement method by blue light, characterized in that 450 to 470 nm band.
The method of claim 6,
The minimum blackening reaction point,
Determined according to whether the test region is contoured, whether pigmentation occurs in an area over a predetermined area of the test area, or whether the melanin index before and after blue light irradiation has changed by more than a predetermined value or by a predetermined ratio or more. Skin change measurement method by the blue light, characterized in that.
The method of claim 6,
Calculating a first minimum blackening amount MPD for test areas not to which the blue light blocking product to be tested is applied; And
And calculating a second minimum blackening amount (MPD) of the test areas to which the blue light blocking product is applied.
The method of claim 6 or 10,
The skin region is a skin change measurement method by blue light, characterized in that the skin area of the type 3 or more of the Fitzpatrick skin type.
The method of claim 11,
The blue light blocking product is a blue light blocking agent,
The blue light protection index (PB) of the blue light blocking agent is a skin change measurement method by blue light, characterized in that calculated by [Equation 1].
[Equation 1]

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