KR20190102059A - 표적화된 TGF-β 억제를 위한 투약 레지멘 및 투여 형태 - Google Patents
표적화된 TGF-β 억제를 위한 투약 레지멘 및 투여 형태 Download PDFInfo
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- KR20190102059A KR20190102059A KR1020197022795A KR20197022795A KR20190102059A KR 20190102059 A KR20190102059 A KR 20190102059A KR 1020197022795 A KR1020197022795 A KR 1020197022795A KR 20197022795 A KR20197022795 A KR 20197022795A KR 20190102059 A KR20190102059 A KR 20190102059A
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| HK1225740A1 (zh) | 2013-08-22 | 2017-09-15 | Acceleron Pharma Inc. | TGF-β受体II型变体及其用途 |
| EP3331550B1 (en) | 2015-08-04 | 2022-11-02 | Acceleron Pharma Inc. | Composition for treating myeloproliferative disorders |
| SI3628049T1 (sl) | 2017-05-04 | 2023-10-30 | Acceleron Pharma Inc. | Fuzijske beljakovine receptorja TGF-beta tipa II in njihova uporaba |
| AU2019288765A1 (en) * | 2018-06-22 | 2021-01-07 | Merck Patent Gmbh | Dosing regimens for targeted TGF-β inhibition for use in treating biliary tract cancer |
| BR112020026902A2 (pt) * | 2018-07-02 | 2021-03-30 | Merck Patent Gmbh | Terapia combinada com inibição direcionada de tgf-b para o tratamento de câncer de pulmão de células não pequenas avançado |
| SG11202100208VA (en) | 2018-07-09 | 2021-02-25 | Precigen Inc | Fusion constructs and methods of using thereof |
| JP7436477B2 (ja) * | 2018-11-09 | 2024-02-21 | ジエンス ヘンルイ メデイシンカンパニー リミテッド | ＴＧＦ－β受容体融合タンパク質医薬組成物およびその使用 |
| MX2021009175A (es) | 2019-01-30 | 2021-09-14 | Scholar Rock Inc | Inhibidores especificos del complejo de ltbp de tgf? y usos de los mismos. |
| AU2020290119B2 (en) * | 2019-06-10 | 2024-07-18 | Shandong Boan Biotechnology Co., Ltd. | Bifunctional fusion protein against PDL1 and TGFβ and use thereof |
| CN112574314A (zh) * | 2019-09-30 | 2021-03-30 | 和铂医药(苏州)有限公司 | 一种融合蛋白及其应用 |
| WO2021081321A1 (en) * | 2019-10-24 | 2021-04-29 | Amgen Inc. | Systems and approaches for drug delivery |
| WO2021084124A1 (en) * | 2019-11-01 | 2021-05-06 | Ares Trading S.A. | COMBINED INHIBITION OF PD-1, TGFβ AND ATM TOGETHER WITH RADIOTHERAPY FOR THE TREATMENT OF CANCER |
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| CN116323657B (zh) * | 2020-09-24 | 2023-12-08 | 上海齐鲁制药研究中心有限公司 | 同时靶向PD-L1和TGFβ的双功能分子及其医药用途 |
| US20240148903A1 (en) | 2021-03-08 | 2024-05-09 | Nanjing GenScript Biotech Co., Ltd. | Delivery of antibody by using dual viral vector system |
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| JP6066732B2 (ja) * | 2010-03-05 | 2017-01-25 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 標的免疫調節抗体および融合タンパク質に基づく組成物および方法 |
| US20130110045A1 (en) * | 2011-10-31 | 2013-05-02 | Ming-Yuan Wu | Single use intravenous therapy administering device with needle safety covers |
| PT3489254T (pt) * | 2012-04-30 | 2022-12-30 | Biocon Ltd | Proteínas de fusão direcionadas/imunomoduladoras e seus métodos de fabrico |
| WO2014193898A1 (en) * | 2013-05-31 | 2014-12-04 | Merck Sharp & Dohme Corp. | Combination therapies for cancer |
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| CN114920840A (zh) * | 2014-10-14 | 2022-08-19 | 诺华股份有限公司 | 针对pd-l1的抗体分子及其用途 |
| CA2975147C (en) * | 2015-01-31 | 2025-06-10 | The Trustees Of The University Of Pennsylvania | COMPOSITIONS AND METHODS OF ADMINISTRATION OF THERAPEUTIC MOLECULES TO T CELLS |
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| MX2017014381A (es) * | 2015-05-12 | 2018-03-02 | Genentech Inc | Metodos terapeuticos y diagnosticos para cancer. |
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| PH12019501574A1 (en) | 2019-11-04 |
| BR112019013924A2 (pt) | 2020-02-11 |
| US20190330375A1 (en) | 2019-10-31 |
| CA3048646A1 (en) | 2018-07-12 |
| SG11201906157YA (en) | 2019-08-27 |
| RU2019124875A (ru) | 2021-02-08 |
| WO2018129331A1 (en) | 2018-07-12 |
| MX2019008001A (es) | 2019-09-09 |
| IL267856A (en) | 2019-09-26 |
| CN110198738A (zh) | 2019-09-03 |
| JP2020514290A (ja) | 2020-05-21 |
| EP3565599A1 (en) | 2019-11-13 |
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