KR20190098211A - 치환 포르피린 약학적 화합물 및 조성물의 제조 방법 - Google Patents

치환 포르피린 약학적 화합물 및 조성물의 제조 방법 Download PDF

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KR20190098211A
KR20190098211A KR1020197021201A KR20197021201A KR20190098211A KR 20190098211 A KR20190098211 A KR 20190098211A KR 1020197021201 A KR1020197021201 A KR 1020197021201A KR 20197021201 A KR20197021201 A KR 20197021201A KR 20190098211 A KR20190098211 A KR 20190098211A
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South Korea
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compound
formula
composition
pyridyl
weight
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Korean (ko)
Inventor
아이네스 바티닉-하벌리
알탁 토브마얀
즈린카 라직 드졸릭
이반 스파소제비크
크리스토퍼 알렌 리
Original Assignee
듀크 유니버시티
바이오미매틱스 제이브이, 엘엘씨
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Publication of KR20190098211A publication Critical patent/KR20190098211A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B47/00—Formation or introduction of functional groups not provided for in groups C07B39/00 - C07B45/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
KR1020197021201A 2016-12-20 2017-12-19 치환 포르피린 약학적 화합물 및 조성물의 제조 방법 Ceased KR20190098211A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662436743P 2016-12-20 2016-12-20
US62/436,743 2016-12-20
PCT/US2017/067263 WO2018118891A1 (en) 2016-12-20 2017-12-19 Methods of making substituted porphyrin pharmaceutical compounds and compositions

Publications (1)

Publication Number Publication Date
KR20190098211A true KR20190098211A (ko) 2019-08-21

Family

ID=62628012

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020197021201A Ceased KR20190098211A (ko) 2016-12-20 2017-12-19 치환 포르피린 약학적 화합물 및 조성물의 제조 방법

Country Status (8)

Country Link
US (1) US20190330220A1 (cg-RX-API-DMAC10.html)
EP (1) EP3558902A4 (cg-RX-API-DMAC10.html)
JP (1) JP2020502280A (cg-RX-API-DMAC10.html)
KR (1) KR20190098211A (cg-RX-API-DMAC10.html)
CN (1) CN110291060A (cg-RX-API-DMAC10.html)
CA (1) CA3046357A1 (cg-RX-API-DMAC10.html)
MX (1) MX2019007301A (cg-RX-API-DMAC10.html)
WO (1) WO2018118891A1 (cg-RX-API-DMAC10.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110621377A (zh) * 2017-04-04 2019-12-27 贝奥密美体合资有限公司 治疗和/或预防与放射和/或化疗暴露有关的副作用的方法、组合物以及试剂盒
CN111417400B (zh) * 2017-09-29 2022-12-02 杜克大学 氟取代的卟啉化合物、包含其的药物组合物及其制备和使用方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127356A (en) * 1993-10-15 2000-10-03 Duke University Oxidant scavengers
ATE312103T1 (de) * 1999-01-25 2005-12-15 Nat Jewish Med & Res Center Substituierte porphyrine und deren therapeutische verwendungen
WO2003103680A1 (en) * 2002-06-07 2003-12-18 Duke University Substituted porphyrins
WO2005077269A1 (en) * 2004-02-09 2005-08-25 Duke University Substituted porphyrins
US20110275606A1 (en) * 2009-01-07 2011-11-10 Duke University Substituted porphyrins
WO2010138633A1 (en) * 2009-05-26 2010-12-02 Duke University Method of providing neuroprotection using substituted porphyrins
WO2015112586A1 (en) * 2014-01-22 2015-07-30 Duke University Methods of treating pruritus

Also Published As

Publication number Publication date
JP2020502280A (ja) 2020-01-23
US20190330220A1 (en) 2019-10-31
EP3558902A1 (en) 2019-10-30
CN110291060A (zh) 2019-09-27
WO2018118891A1 (en) 2018-06-28
MX2019007301A (es) 2019-10-30
EP3558902A4 (en) 2020-06-24
CA3046357A1 (en) 2018-06-28

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