KR20190077471A - 방향 선택적인 망막 신경절 세포에서의 유전자의 특이적 발현을 위한 프로모터, synp198 - Google Patents

방향 선택적인 망막 신경절 세포에서의 유전자의 특이적 발현을 위한 프로모터, synp198 Download PDF

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KR20190077471A
KR20190077471A KR1020197015426A KR20197015426A KR20190077471A KR 20190077471 A KR20190077471 A KR 20190077471A KR 1020197015426 A KR1020197015426 A KR 1020197015426A KR 20197015426 A KR20197015426 A KR 20197015426A KR 20190077471 A KR20190077471 A KR 20190077471A
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nucleic acid
cell
gene
sequence
acid sequence
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도미니크 하르틀
조세핀 위트너
아르나우트 크렙스
보톤트 로스카
디르크 쉬벨러
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프리드리히 미셔 인스티튜트 포 바이오메디칼 리서치
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KR1020197015426A 2016-11-02 2017-11-01 방향 선택적인 망막 신경절 세포에서의 유전자의 특이적 발현을 위한 프로모터, synp198 Ceased KR20190077471A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16196818.5 2016-11-02
EP16196818 2016-11-02
PCT/IB2017/056792 WO2018083607A1 (en) 2016-11-02 2017-11-01 Synp198, a promoter for the specific expression of genes in direction selective retinal ganglion cells

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KR20190077471A true KR20190077471A (ko) 2019-07-03

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US (1) US11525145B2 (https=)
EP (1) EP3534966B1 (https=)
JP (1) JP7023279B2 (https=)
KR (1) KR20190077471A (https=)
CN (1) CN110072557B (https=)
AU (1) AU2017354086C1 (https=)
BR (1) BR112019008488A2 (https=)
CA (1) CA3042197A1 (https=)
IL (1) IL266115A (https=)
RU (1) RU2766353C2 (https=)
WO (1) WO2018083607A1 (https=)

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MX2010011467A (es) 2008-04-18 2011-02-15 Novartis Forschungsstiftung Novedosas herramientas y metodos terapeuticos para tratar la ceguera.
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US10857241B2 (en) 2015-09-15 2020-12-08 Friedrich Miescher Institute For Biomedical Research Therapeutical tools and methods for treating blindness by targeting photoreceptors
WO2017064642A1 (en) 2015-10-14 2017-04-20 Fredrich Miescher Institute For Biomedical Research Promoter for the specific expression of genes in retinal endothelial cells
EP3383440B1 (en) 2015-12-03 2021-06-30 Friedrich Miescher Institute for Biomedical Research Synp162, a promoter for the specific expression of genes in rod photoreceptors
EP3383439B1 (en) 2015-12-03 2019-09-25 Friedrich Miescher Institute for Biomedical Research Synp161, a promoter for the specific expression of genes in rod photoreceptors
WO2017093934A1 (en) 2015-12-03 2017-06-08 Friedrich Miescher Institute For Biomedical Research Synp160, a promoter for the specific expression of genes in rod photoreceptors
ES2909444T3 (es) 2015-12-03 2022-05-06 Friedrich Miescher Institute For Biomedical Res Synp159, un promotor para la expresión específica de genes en los fotorreceptores de los bastones
RU2766353C2 (ru) 2016-11-02 2022-03-15 Фридрих Мишер Инститьют Фор Байомедикал Рисерч Synp198, промотор для специфической экспрессии генов в ганглионарных клетках сетчатки, избирательных в отношении направления
WO2018146588A1 (en) 2017-02-08 2018-08-16 Friedrich Miescher Institute For Biomedical Research Synp88, a promoter for the specific expression of genes in retinal ganglion cells
MX2020005033A (es) 2017-11-15 2020-10-28 Friedrich Miescher Institute For Biomedical Res Promotor especifico de las celulas del epitelio pigmentario retinal en primates.
SG11202005024QA (en) 2017-11-30 2020-06-29 Friedrich Miescher Institute For Biomedical Res Synpiii, a promoter for the specific expression of genes in retinal pigment epithelium
JP2022505517A (ja) * 2018-10-25 2022-01-14 フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ 網膜神経節細胞中の遺伝子の特異的発現のためのプロモーターSynP151(ProC29)
JP2024507860A (ja) * 2021-02-22 2024-02-21 ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・コロラド、ア・ボデイー・コーポレイト 眼病態に対するウイルスベクターベースの遺伝子療法

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CN101484005A (zh) * 2006-05-04 2009-07-15 韦恩州立大学 通过向体内递送视紫红质核酸恢复视觉响应
EP1891976A1 (en) 2006-08-23 2008-02-27 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute for Biomedical Research Use of light sensitive genes
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CA2962219C (en) * 2008-10-22 2020-08-25 Quark Pharmaceuticals, Inc. Methods for treating eye disorders
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EP3548093A1 (en) 2016-12-01 2019-10-09 Friedrich Miescher Institute for Biomedical Research Synp107, a promoter for the specific expression of genes in interneurons
US20190376083A1 (en) 2016-12-01 2019-12-12 Friedrich Miescher Institute For Biomedical Research Synp1, a promoter for the specific expression of genes in interneurons
WO2018146588A1 (en) 2017-02-08 2018-08-16 Friedrich Miescher Institute For Biomedical Research Synp88, a promoter for the specific expression of genes in retinal ganglion cells
MX2020005033A (es) 2017-11-15 2020-10-28 Friedrich Miescher Institute For Biomedical Res Promotor especifico de las celulas del epitelio pigmentario retinal en primates.
CN111527102A (zh) 2017-11-30 2020-08-11 弗里德里克·米谢尔生物医学研究所 灵长类动物视网膜色素上皮细胞特异性启动子SynP61
SG11202005024QA (en) 2017-11-30 2020-06-29 Friedrich Miescher Institute For Biomedical Res Synpiii, a promoter for the specific expression of genes in retinal pigment epithelium
JP2022505517A (ja) 2018-10-25 2022-01-14 フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ 網膜神経節細胞中の遺伝子の特異的発現のためのプロモーターSynP151(ProC29)
EP3870709A1 (en) 2018-10-25 2021-09-01 Friedrich Miescher Institute for Biomedical Research Synp27 (prob12), a promoter for the specific expression of genes in protoplasmic astrocytes
EP3870240A1 (en) 2018-10-25 2021-09-01 Friedrich Miescher Institute for Biomedical Research Synp78 (proa27), a promoter for the specific expression of genes in retinal ganglion cells
EP3870239A1 (en) 2018-10-25 2021-09-01 Friedrich Miescher Institute for Biomedical Research Synp57 (proa14), a promoter for the specific expression of genes in photoreceptors
WO2020084537A1 (en) 2018-10-25 2020-04-30 Friedrich Miescher Institute For Biomedical Research Synp17 (prob1), a promoter for the specific expression of genes in retinal ganglion cells
US20210353773A1 (en) 2018-10-25 2021-11-18 Friedrich Miescher Institute For Biomedical Research Synp194 (prob15), a promoter for the specific expression of genes in retinal ganglion cells
US20220119807A1 (en) 2019-01-24 2022-04-21 Friedrich Miescher Institute For Biomedical Research Synp35 (proc8), a promoter for the specific expression of genes in retinal ganglion cells
EP3914300A1 (en) 2019-01-24 2021-12-01 Friedrich Miescher Institute for Biomedical Research Synp66 (proa21), a promoter for the specific expression of genes in retinal ganglion cells
US20220119841A1 (en) 2019-01-24 2022-04-21 Friedrich Miescher Instit for Biomedical Research Synp5 (proa9), a promoter for the specific expression of genes in retinal ganglion cells
WO2020152626A1 (en) 2019-01-24 2020-07-30 Friedrich Miescher Institute For Biomedical Research Synp166 (proa36), a promoter for the specific expression of genes in photoreceptors
SG11202108044YA (en) 2019-02-25 2021-09-29 Novartis Ag Compositions and methods to treat bietti crystalline dystrophy
US20220154211A1 (en) 2019-02-25 2022-05-19 Novartis Ag Compositions and methods to treat bietti crystalline dystrophy

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JP2019537437A (ja) 2019-12-26
CN110072557B (zh) 2022-11-11
EP3534966B1 (en) 2024-06-19
US20190276847A1 (en) 2019-09-12
BR112019008488A2 (pt) 2019-07-09
US11525145B2 (en) 2022-12-13
CN110072557A (zh) 2019-07-30
RU2019115117A3 (https=) 2021-03-23
AU2017354086B2 (en) 2021-01-28
AU2017354086C1 (en) 2021-05-06
WO2018083607A1 (en) 2018-05-11
IL266115A (en) 2019-06-30
CA3042197A1 (en) 2018-05-11
RU2019115117A (ru) 2020-12-03
AU2017354086A1 (en) 2019-05-09
EP3534966A1 (en) 2019-09-11
RU2766353C2 (ru) 2022-03-15

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