KR20190064583A - Chs-131로 다발성 경화증의 치료 - Google Patents

Chs-131로 다발성 경화증의 치료 Download PDF

Info

Publication number
KR20190064583A
KR20190064583A KR1020197009963A KR20197009963A KR20190064583A KR 20190064583 A KR20190064583 A KR 20190064583A KR 1020197009963 A KR1020197009963 A KR 1020197009963A KR 20197009963 A KR20197009963 A KR 20197009963A KR 20190064583 A KR20190064583 A KR 20190064583A
Authority
KR
South Korea
Prior art keywords
effective amount
therapeutically effective
compound
multiple sclerosis
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020197009963A
Other languages
English (en)
Korean (ko)
Inventor
바바라 핑크
로버트 지바디노
홍 탕
Original Assignee
인테크린 테라퓨틱스, 아이엔씨.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 인테크린 테라퓨틱스, 아이엔씨. filed Critical 인테크린 테라퓨틱스, 아이엔씨.
Publication of KR20190064583A publication Critical patent/KR20190064583A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020197009963A 2016-09-13 2017-09-13 Chs-131로 다발성 경화증의 치료 Ceased KR20190064583A (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201662394046P 2016-09-13 2016-09-13
US62/394,046 2016-09-13
US201662436356P 2016-12-19 2016-12-19
US62/436,356 2016-12-19
US201762460868P 2017-02-19 2017-02-19
US62/460,868 2017-02-19
US201762491071P 2017-04-27 2017-04-27
US62/491,071 2017-04-27
PCT/US2017/051414 WO2018053040A1 (en) 2016-09-13 2017-09-13 Treatment of multiple sclerosis with chs-131

Publications (1)

Publication Number Publication Date
KR20190064583A true KR20190064583A (ko) 2019-06-10

Family

ID=61619253

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020197009963A Ceased KR20190064583A (ko) 2016-09-13 2017-09-13 Chs-131로 다발성 경화증의 치료

Country Status (12)

Country Link
US (1) US20190224186A1 (cg-RX-API-DMAC7.html)
EP (1) EP3512512A4 (cg-RX-API-DMAC7.html)
JP (1) JP2019531286A (cg-RX-API-DMAC7.html)
KR (1) KR20190064583A (cg-RX-API-DMAC7.html)
CN (1) CN110461318A (cg-RX-API-DMAC7.html)
AU (1) AU2017326261A1 (cg-RX-API-DMAC7.html)
BR (1) BR112019004791A2 (cg-RX-API-DMAC7.html)
CA (1) CA3036694A1 (cg-RX-API-DMAC7.html)
IL (1) IL265259A (cg-RX-API-DMAC7.html)
MX (1) MX2019002901A (cg-RX-API-DMAC7.html)
SG (1) SG10202102198RA (cg-RX-API-DMAC7.html)
WO (1) WO2018053040A1 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130158077A1 (en) 2011-12-19 2013-06-20 Ares Trading S.A. Pharmaceutical compositions
CN107683135A (zh) 2015-03-09 2018-02-09 因特克林医疗有限公司 用于治疗非酒精性脂肪肝疾病和/或脂肪营养不良的方法
AU2018249822A1 (en) 2017-04-03 2019-10-31 Coherus Biosciences Inc. PPArgamma agonist for treatment of progressive supranuclear palsy
EA201992364A1 (ru) * 2018-04-02 2020-03-23 Кохерус Байосайенсис Инк. АГОНИСТ PPARγ ДЛЯ ЛЕЧЕНИЯ ПРОГРЕССИРУЮЩЕГО НАДЪЯДЕРНОГО ПАРАЛИЧА

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7223761B2 (en) * 2003-10-03 2007-05-29 Amgen Inc. Salts and polymorphs of a potent antidiabetic compound
MX2015004564A (es) * 2012-10-12 2015-07-21 Teva Pharma Laquinimod para producir el daño talamico en la esclerosis multiple.
HK1218510A1 (zh) * 2013-01-30 2017-02-24 Intekrin Therapeutics, Inc. 用於治療多發性硬化症的PPARγ激動劑

Also Published As

Publication number Publication date
CN110461318A (zh) 2019-11-15
IL265259A (en) 2019-05-30
JP2019531286A (ja) 2019-10-31
EP3512512A1 (en) 2019-07-24
CA3036694A1 (en) 2018-03-22
EP3512512A4 (en) 2020-06-03
AU2017326261A1 (en) 2019-04-04
US20190224186A1 (en) 2019-07-25
BR112019004791A2 (pt) 2019-06-04
WO2018053040A1 (en) 2018-03-22
MX2019002901A (es) 2019-09-26
SG10202102198RA (en) 2021-04-29

Similar Documents

Publication Publication Date Title
EP3206682B1 (en) Combinations comprising siponimod and laquinimod for the treatment of multiple sclerosis
KR20160067103A (ko) 신경 장애를 치료하기 위한 토라세미드 및 바클로펜을 포함하는 조성물
JP2015515985A (ja) 多発性硬化症を治療するための高投与量ラキニモドの使用
CN102143687B (zh) 4-氨基吡啶在改善具有脱髓鞘和其它神经系统状况的患者的神经-认知和/或神经-精神病学损伤中的用途
KR102056756B1 (ko) 다발성 경화증의 치료를 위한 PPARγ 작용제
RS64481B1 (sr) Lečenje alchajmerove bolesti kod posebne populacije pacijenata
US12318380B2 (en) Treatment of demyelinating diseases
EP2882495A1 (en) Laquinimod for treatment of cannabinoid receptor type 1 (cb1) mediated disorders
AU2025271046A1 (en) New therapeutic combinations for the treatment of progressive fibrosing interstitial lung diseases
US20190224186A1 (en) Treatment of multiple sclerosis with chs-131
JP2019505549A (ja) PIK3CA関連過成長症候群(PROS CLOVaS症候群)の処置に使用するためのBYL719(アルペリシブ)
KR20120050512A (ko) 탈수초를 갖는 환자에서 4-아미노피리딘을 사용한 지속적 치료
JP2019532112A (ja) 結節性痒疹の治療方法
JP5119919B2 (ja) 多発性硬化症に伴う痒みに対する止痒剤
US9492454B2 (en) Use of pemirolast in the treatment of acute asthma
Kobayashi et al. Anti-asthmatic effect of ASP3258, a novel phosphodiesterase 4 inhibitor
JP2022515615A (ja) 慢性炎症性腸疾患の治療のためのpar-1アンタゴニストの使用
US20240299410A1 (en) Methods of treating familial amyotrophic lateral sclerosis by oral administration of fasudil
RU2805061C2 (ru) Лечение демиелинизирующих заболеваний
US20160310493A1 (en) Use of pemirolast in the treatment of acute asthma
RU2025126577A (ru) Пептиды-антагонисты рецептора интерлейкина-23 для применения в лечении псориаза
EP4699605A1 (en) Use of novel compound for treating intractable diseases

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20190408

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20200914

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20221213

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20230217

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20221213

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I