KR20190046935A - 엔자스타우린의 활성을 예측하기 위한 방법 및 조성물 - Google Patents

엔자스타우린의 활성을 예측하기 위한 방법 및 조성물 Download PDF

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KR20190046935A
KR20190046935A KR1020197009407A KR20197009407A KR20190046935A KR 20190046935 A KR20190046935 A KR 20190046935A KR 1020197009407 A KR1020197009407 A KR 1020197009407A KR 20197009407 A KR20197009407 A KR 20197009407A KR 20190046935 A KR20190046935 A KR 20190046935A
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treatment
sequence
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cancer
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Korean (ko)
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웬 루오
홍 선
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드노보 바이오파마 엘엘씨
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Publication of KR20190046935A publication Critical patent/KR20190046935A/ko
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
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  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
KR1020197009407A 2016-09-01 2017-08-31 엔자스타우린의 활성을 예측하기 위한 방법 및 조성물 Ceased KR20190046935A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662382734P 2016-09-01 2016-09-01
US62/382,734 2016-09-01
US201662414601P 2016-10-28 2016-10-28
US62/414,601 2016-10-28
PCT/US2017/049747 WO2018045240A1 (en) 2016-09-01 2017-08-31 Methods and composition for the prediction of the activity of enzastaurin

Publications (1)

Publication Number Publication Date
KR20190046935A true KR20190046935A (ko) 2019-05-07

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020197009407A Ceased KR20190046935A (ko) 2016-09-01 2017-08-31 엔자스타우린의 활성을 예측하기 위한 방법 및 조성물

Country Status (15)

Country Link
US (2) US11421280B2 (https=)
EP (1) EP3507384B1 (https=)
JP (3) JP7197915B2 (https=)
KR (1) KR20190046935A (https=)
CN (1) CN109952383B (https=)
AU (1) AU2017318669B2 (https=)
BR (1) BR112019003951A2 (https=)
CA (1) CA3035386A1 (https=)
JO (1) JOP20190025A1 (https=)
MX (1) MX2019002377A (https=)
PH (1) PH12019500422A1 (https=)
RU (1) RU2019109011A (https=)
SG (2) SG11201901762WA (https=)
TW (2) TW202313973A (https=)
WO (1) WO2018045240A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20190025A1 (ar) 2016-09-01 2019-02-19 Denovo Biopharma Llc طرق وتركيبة لتوقع نشاط إنزاستورين
CN110496223B (zh) * 2018-05-17 2021-09-10 复旦大学附属肿瘤医院 一种治疗非霍奇金氏淋巴瘤的药物组合物
EP3849559A4 (en) * 2018-09-12 2022-06-01 Denovo Biopharma LLC COMBINATION OF ENZASTAURIN AND INHIBITORS OF BTK AND USES THEREOF
CN111549033B (zh) * 2020-06-11 2021-02-12 南京市江宁医院 慢病毒感染人表皮角质细胞株及其构建方法和应用
US11227690B1 (en) * 2020-09-14 2022-01-18 Opendna Ltd. Machine learning prediction of therapy response
EP4376022A4 (en) * 2021-07-23 2025-07-16 Univ Kaohsiung Medical CLINICAL THERAPEUTIC DRUG PREDICTION AND RECOMMENDATION SYSTEM AND METHOD FOR EVALUATING THE EFFICACY OF A SECOND-GENERATION HORMONAL DRUG IN THE TREATMENT OF PROSTATE CANCER
US20230131677A1 (en) * 2021-10-21 2023-04-27 Toyota Research Institute, Inc. Systems and methods for predicting the effect of an intervention via machine learning
WO2023097197A2 (en) * 2021-11-23 2023-06-01 Denovo Biopharma Llc Compositions and methods for assessing the efficacy of polynucleotide delivery and cancer therapy
US12474842B2 (en) * 2021-12-13 2025-11-18 Google Llc Optimizing data placement based on data temperature and lifetime prediction

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2179650C (en) 1993-12-23 2007-10-30 William Francis Heath, Jr. Bisindolemaleimides and their use as protein kinase c inhibitors
WO2002014500A2 (en) * 2000-08-16 2002-02-21 Chiron Corporation Human genes and gene expression products
US20040072217A1 (en) 2002-06-17 2004-04-15 Affymetrix, Inc. Methods of analysis of linkage disequilibrium
CA2393720C (en) 2002-07-12 2010-09-14 Eli Lilly And Company Crystalline 2,5-dione-3-(1-methyl-1h-indol-3-yl)-4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1h-indol-3-yl]-1h-pyrrole mono-hydrochloride
US20080299125A1 (en) 2006-06-05 2008-12-04 Perlegen Sciences, Inc. Genetic basis of treatment response in depression patients
EP2707498B1 (en) 2011-01-31 2018-01-17 Denovo Biomarkers Inc. Method for discovering pharmacogenomic biomarkers
CA2838207A1 (en) 2011-06-08 2012-12-13 Denovo Biopharma (Hangzhou) Ltd. Co. Methods and compositions of predicting activity of retinoid x receptor modulator
JOP20190025A1 (ar) 2016-09-01 2019-02-19 Denovo Biopharma Llc طرق وتركيبة لتوقع نشاط إنزاستورين

Also Published As

Publication number Publication date
RU2019109011A (ru) 2020-10-05
TWI771317B (zh) 2022-07-21
AU2017318669B2 (en) 2023-04-20
JOP20190025A1 (ar) 2019-02-19
CN109952383A (zh) 2019-06-28
JP7197915B2 (ja) 2022-12-28
MX2019002377A (es) 2019-09-05
CA3035386A1 (en) 2018-03-08
JP2020188816A (ja) 2020-11-26
BR112019003951A2 (pt) 2019-06-25
AU2017318669A1 (en) 2019-03-07
WO2018045240A1 (en) 2018-03-08
EP3507384A1 (en) 2019-07-10
JP2022173308A (ja) 2022-11-18
TW201812125A (zh) 2018-04-01
SG11201901762WA (en) 2019-03-28
JP2019528705A (ja) 2019-10-17
US20230074781A1 (en) 2023-03-09
US20190233902A1 (en) 2019-08-01
RU2019109011A3 (https=) 2021-01-22
US11421280B2 (en) 2022-08-23
SG10201912134TA (en) 2020-02-27
PH12019500422A1 (en) 2019-05-27
TW202313973A (zh) 2023-04-01
EP3507384B1 (en) 2023-08-30
CN109952383B (zh) 2024-01-05

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