KR20190028664A - 암의 치료를 위한 면역 체크포인트 억제제와 세포독성 t 세포 - Google Patents

암의 치료를 위한 면역 체크포인트 억제제와 세포독성 t 세포 Download PDF

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KR20190028664A
KR20190028664A KR1020187037498A KR20187037498A KR20190028664A KR 20190028664 A KR20190028664 A KR 20190028664A KR 1020187037498 A KR1020187037498 A KR 1020187037498A KR 20187037498 A KR20187037498 A KR 20187037498A KR 20190028664 A KR20190028664 A KR 20190028664A
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peptide
ctl
cell
immune checkpoint
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KR1020187037498A
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English (en)
Korean (ko)
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라지브 칸나
코리 스미스
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더 카운실 오브 더 퀸즐랜드 인스티튜트 오브 메디컬 리서치
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Publication of KR20190028664A publication Critical patent/KR20190028664A/ko

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/31Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
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    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K39/46
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • A61K39/4643Vertebrate antigens
    • A61K39/4644Cancer antigens
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    • A61K39/464838Viral antigens
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • C12N5/0638Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K2317/00Immunoglobulins specific features
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    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
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  • Gastroenterology & Hepatology (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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KR1020187037498A 2016-05-25 2017-05-25 암의 치료를 위한 면역 체크포인트 억제제와 세포독성 t 세포 KR20190028664A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662341402P 2016-05-25 2016-05-25
US62/341,402 2016-05-25
PCT/IB2017/000740 WO2017203362A1 (fr) 2016-05-25 2017-05-25 Inhibiteurs du point de contrôle immunitaire et lymphocytes t cytotoxiques pour le traitement du cancer

Publications (1)

Publication Number Publication Date
KR20190028664A true KR20190028664A (ko) 2019-03-19

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KR1020187037498A KR20190028664A (ko) 2016-05-25 2017-05-25 암의 치료를 위한 면역 체크포인트 억제제와 세포독성 t 세포

Country Status (9)

Country Link
EP (1) EP3463398A4 (fr)
JP (1) JP2019516768A (fr)
KR (1) KR20190028664A (fr)
CN (1) CN109496155A (fr)
AR (1) AR108624A1 (fr)
AU (1) AU2017271128A1 (fr)
CA (1) CA3023845A1 (fr)
SG (1) SG11201809541UA (fr)
WO (1) WO2017203362A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7364237B2 (ja) * 2017-08-10 2023-10-18 グッド ティー セルズ、 インコーポレイテッド 癌治療のためのt細胞の活性化方法
WO2020227279A1 (fr) * 2019-05-06 2020-11-12 Hasumi International Research Foundation Thérapie et méthode permettant d'introduire des cellules dendritiques immatures et/ou des lymphocytes t cytotoxiques et des anticorps anti-pd-1 / pd-l1 pour le traitement de tumeurs
CN110452870A (zh) * 2019-05-20 2019-11-15 河南省肿瘤医院 一种肿瘤特异性t细胞的分离培养方法及由其获得的产品
WO2021077175A1 (fr) * 2019-10-23 2021-04-29 The Council Of The Queensland Institute Of Medical Research Immunothérapie adoptive

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Publication number Priority date Publication date Assignee Title
WO2002086083A2 (fr) * 2001-04-20 2002-10-31 Mayo Foundation For Medical Education And Research Procedes d'amelioration de la capacite de reaction de cellules t
CN101663323A (zh) * 2006-12-27 2010-03-03 埃默里大学 用于治疗传染病和肿瘤的组合物和方法
US8883500B2 (en) * 2008-12-05 2014-11-11 Northeastern University Method of preparing adenosine-resistant anti-tumor T lymphocytes for adoptive immunotherapy
CN104769104A (zh) * 2011-12-12 2015-07-08 细胞药物有限公司 扩大t细胞的方法
CN109793893B (zh) * 2012-09-07 2023-05-26 达特茅斯大学理事会 用于诊断和治疗癌症的vista调节剂
MX2016005925A (es) * 2013-11-05 2016-11-28 Cognate Bioservices Inc Combinaciones de inhibidores de punto de regulacion y terapeuticos para tratar el cancer.
US20170044496A1 (en) * 2014-04-10 2017-02-16 H. Lee Moffitt Cancer Center And Research Institute, Inc. Enhanced Expansion of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy
SG11201702191YA (en) * 2014-09-17 2017-04-27 Univ Johns Hopkins Reagents and methods for identifying, enriching, and/or expanding antigen-specific t cells
SG10201903912XA (en) * 2014-10-31 2019-05-30 Massachusetts Inst Technology Delivery of biomolecules to immune cells

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CA3023845A1 (fr) 2017-11-30
AU2017271128A1 (en) 2019-01-03
JP2019516768A (ja) 2019-06-20
WO2017203362A1 (fr) 2017-11-30
CN109496155A (zh) 2019-03-19
EP3463398A1 (fr) 2019-04-10
EP3463398A4 (fr) 2020-03-11
SG11201809541UA (en) 2018-12-28
AR108624A1 (es) 2018-09-12

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