CA3023845A1 - Inhibiteurs du point de controle immunitaire et lymphocytes t cytotoxiques pour le traitement du cancer - Google Patents
Inhibiteurs du point de controle immunitaire et lymphocytes t cytotoxiques pour le traitement du cancer Download PDFInfo
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- CA3023845A1 CA3023845A1 CA3023845A CA3023845A CA3023845A1 CA 3023845 A1 CA3023845 A1 CA 3023845A1 CA 3023845 A CA3023845 A CA 3023845A CA 3023845 A CA3023845 A CA 3023845A CA 3023845 A1 CA3023845 A1 CA 3023845A1
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- immune checkpoint
- peptide
- ctls
- cells
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Abstract
L'invention concerne des méthodes de traitement du cancer consistant à administrer conjointement un inhibiteur du point de contrôle immunitaire et une composition comprenant des lymphocytes T cytotoxiques (CTL).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662341402P | 2016-05-25 | 2016-05-25 | |
US62/341,402 | 2016-05-25 | ||
PCT/IB2017/000740 WO2017203362A1 (fr) | 2016-05-25 | 2017-05-25 | Inhibiteurs du point de contrôle immunitaire et lymphocytes t cytotoxiques pour le traitement du cancer |
Publications (1)
Publication Number | Publication Date |
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CA3023845A1 true CA3023845A1 (fr) | 2017-11-30 |
Family
ID=60411124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CA3023845A Abandoned CA3023845A1 (fr) | 2016-05-25 | 2017-05-25 | Inhibiteurs du point de controle immunitaire et lymphocytes t cytotoxiques pour le traitement du cancer |
Country Status (9)
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EP (1) | EP3463398A4 (fr) |
JP (1) | JP2019516768A (fr) |
KR (1) | KR20190028664A (fr) |
CN (1) | CN109496155A (fr) |
AR (1) | AR108624A1 (fr) |
AU (1) | AU2017271128A1 (fr) |
CA (1) | CA3023845A1 (fr) |
SG (1) | SG11201809541UA (fr) |
WO (1) | WO2017203362A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111433355B (zh) * | 2017-08-10 | 2024-03-29 | 古德T细胞有限公司 | 用于癌症治疗的t细胞的活化方法 |
WO2020227279A1 (fr) * | 2019-05-06 | 2020-11-12 | Hasumi International Research Foundation | Thérapie et méthode permettant d'introduire des cellules dendritiques immatures et/ou des lymphocytes t cytotoxiques et des anticorps anti-pd-1 / pd-l1 pour le traitement de tumeurs |
CN110452870A (zh) * | 2019-05-20 | 2019-11-15 | 河南省肿瘤医院 | 一种肿瘤特异性t细胞的分离培养方法及由其获得的产品 |
AU2020371562A1 (en) * | 2019-10-23 | 2022-06-09 | The Council Of The Queensland Institute Of Medical Research | Adoptive immunotherapy |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
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AU2002258941A1 (en) * | 2001-04-20 | 2002-11-05 | Mayo Foundation For Medical Education And Research | Methods of enhancing cell responsiveness |
NZ594510A (en) * | 2006-12-27 | 2012-06-29 | Harvard College | Compositions and methods for the treatment of infections and tumors |
US8883500B2 (en) * | 2008-12-05 | 2014-11-11 | Northeastern University | Method of preparing adenosine-resistant anti-tumor T lymphocytes for adoptive immunotherapy |
JP6081483B2 (ja) * | 2011-12-12 | 2017-02-15 | セル・メディカ・リミテッド | T細胞を増殖させるプロセス |
CN109793893B (zh) * | 2012-09-07 | 2023-05-26 | 达特茅斯大学理事会 | 用于诊断和治疗癌症的vista调节剂 |
BR112016010224A2 (pt) * | 2013-11-05 | 2018-05-02 | Cognate Bioservices, Inc. | combinações de inibidores do ponto de verificação e produtos terapêuticos para tratar o câncer. |
US20170044496A1 (en) * | 2014-04-10 | 2017-02-16 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Enhanced Expansion of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy |
US10987412B2 (en) * | 2014-09-17 | 2021-04-27 | The John Hopkins University | Reagents and methods for identifying, enriching, and/or expanding antigen-specific T cells |
BR112017009050A2 (pt) * | 2014-10-31 | 2018-01-30 | Massachusetts Inst Technology | entrega de biomoléculas a células imunes |
-
2017
- 2017-05-25 CN CN201780045909.0A patent/CN109496155A/zh active Pending
- 2017-05-25 EP EP17802270.3A patent/EP3463398A4/fr not_active Withdrawn
- 2017-05-25 JP JP2018561725A patent/JP2019516768A/ja not_active Withdrawn
- 2017-05-25 KR KR1020187037498A patent/KR20190028664A/ko unknown
- 2017-05-25 AU AU2017271128A patent/AU2017271128A1/en not_active Abandoned
- 2017-05-25 WO PCT/IB2017/000740 patent/WO2017203362A1/fr unknown
- 2017-05-25 CA CA3023845A patent/CA3023845A1/fr not_active Abandoned
- 2017-05-25 SG SG11201809541UA patent/SG11201809541UA/en unknown
- 2017-05-26 AR ARP170101457A patent/AR108624A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
KR20190028664A (ko) | 2019-03-19 |
JP2019516768A (ja) | 2019-06-20 |
SG11201809541UA (en) | 2018-12-28 |
WO2017203362A1 (fr) | 2017-11-30 |
EP3463398A1 (fr) | 2019-04-10 |
EP3463398A4 (fr) | 2020-03-11 |
AU2017271128A1 (en) | 2019-01-03 |
CN109496155A (zh) | 2019-03-19 |
AR108624A1 (es) | 2018-09-12 |
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