KR20190017017A - 프로테아제-내성 모노-지질화된 펩타이드 - Google Patents

프로테아제-내성 모노-지질화된 펩타이드 Download PDF

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Publication number
KR20190017017A
KR20190017017A KR1020197000408A KR20197000408A KR20190017017A KR 20190017017 A KR20190017017 A KR 20190017017A KR 1020197000408 A KR1020197000408 A KR 1020197000408A KR 20197000408 A KR20197000408 A KR 20197000408A KR 20190017017 A KR20190017017 A KR 20190017017A
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KR
South Korea
Prior art keywords
glu
gly
lys
ala
artificial sequence
Prior art date
Application number
KR1020197000408A
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English (en)
Korean (ko)
Inventor
마리아 에이 베드나렉
Original Assignee
메디뮨 리미티드
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Publication date
Application filed by 메디뮨 리미티드 filed Critical 메디뮨 리미티드
Publication of KR20190017017A publication Critical patent/KR20190017017A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020197000408A 2016-06-09 2017-06-08 프로테아제-내성 모노-지질화된 펩타이드 KR20190017017A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662347693P 2016-06-09 2016-06-09
US62/347,693 2016-06-09
PCT/EP2017/063905 WO2017211922A2 (fr) 2016-06-09 2017-06-08 Peptides mono-lipidés résistants aux protéases

Publications (1)

Publication Number Publication Date
KR20190017017A true KR20190017017A (ko) 2019-02-19

Family

ID=59078034

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020197000408A KR20190017017A (ko) 2016-06-09 2017-06-08 프로테아제-내성 모노-지질화된 펩타이드

Country Status (10)

Country Link
EP (1) EP3468987A2 (fr)
JP (1) JP2019525732A (fr)
KR (1) KR20190017017A (fr)
CN (1) CN109195984A (fr)
AU (1) AU2017277594A1 (fr)
BR (1) BR112018072968A2 (fr)
CA (1) CA3025592A1 (fr)
IL (1) IL263292A (fr)
MX (1) MX2018014966A (fr)
WO (1) WO2017211922A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11045522B2 (en) * 2017-09-22 2021-06-29 Regeneren Pharmaceuticals, Inc. Glucagon-like peptide 1 receptor agonists and uses thereof
SI4122954T1 (sl) 2018-04-05 2024-07-31 Sun Pharmaceutical Industries Limited Novi analogi GLP-1
KR102691149B1 (ko) 2021-01-20 2024-08-05 바이킹 테라퓨틱스 인코포레이티드 대사 및 간 질환 치료를 위한 조성물 및 방법
TW202346323A (zh) * 2022-02-07 2023-12-01 英商梅迪繆思有限公司 具有改善的生物穩定性的ｇｌｐ—１及升糖素雙重激動肽

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2057189B1 (fr) * 2006-08-25 2013-03-06 Novo Nordisk A/S Composés d'exendine-4 acylée
WO2015086686A2 (fr) 2013-12-13 2015-06-18 Medimmune Limited Peptides résistant aux protéases
TWI726889B (zh) * 2015-06-10 2021-05-11 英商梅迪繆思有限公司 蛋白酶抗性之脂化肽

Also Published As

Publication number Publication date
CA3025592A1 (fr) 2017-12-14
BR112018072968A2 (pt) 2019-02-19
MX2018014966A (es) 2019-08-14
AU2017277594A1 (en) 2019-02-07
EP3468987A2 (fr) 2019-04-17
CN109195984A (zh) 2019-01-11
IL263292A (en) 2018-12-31
JP2019525732A (ja) 2019-09-12
WO2017211922A3 (fr) 2018-01-18
WO2017211922A2 (fr) 2017-12-14

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