KR20180120145A - 렙틴-결핍 병태를 치료하기 위한 cd24 단백질의 용도 - Google Patents
렙틴-결핍 병태를 치료하기 위한 cd24 단백질의 용도 Download PDFInfo
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- KR20180120145A KR20180120145A KR1020187022125A KR20187022125A KR20180120145A KR 20180120145 A KR20180120145 A KR 20180120145A KR 1020187022125 A KR1020187022125 A KR 1020187022125A KR 20187022125 A KR20187022125 A KR 20187022125A KR 20180120145 A KR20180120145 A KR 20180120145A
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- 239000007929 subcutaneous injection Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000011285 therapeutic regimen Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000041 toxicology testing Toxicity 0.000 description 1
- YNIRKEZIDLCCMC-UHFFFAOYSA-K trisodium;phosphate;hydrate Chemical compound [OH-].[Na+].[Na+].[Na+].OP([O-])([O-])=O YNIRKEZIDLCCMC-UHFFFAOYSA-K 0.000 description 1
- 125000002987 valine group Chemical group [H]N([H])C([H])(C(*)=O)C([H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 108010073969 valyllysine Proteins 0.000 description 1
- 239000013603 viral vector Substances 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2264—Obesity-gene products, e.g. leptin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662290202P | 2016-02-02 | 2016-02-02 | |
| US62/290,202 | 2016-02-02 | ||
| PCT/US2017/016120 WO2017136492A1 (en) | 2016-02-02 | 2017-02-02 | Use of cd24 proteins for treating leptin-deficient conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20180120145A true KR20180120145A (ko) | 2018-11-05 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020187022125A Ceased KR20180120145A (ko) | 2016-02-02 | 2017-02-02 | 렙틴-결핍 병태를 치료하기 위한 cd24 단백질의 용도 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10799558B2 (enExample) |
| EP (1) | EP3411062B1 (enExample) |
| JP (1) | JP6938835B2 (enExample) |
| KR (1) | KR20180120145A (enExample) |
| CN (1) | CN109069583B (enExample) |
| CA (1) | CA3012466A1 (enExample) |
| SG (1) | SG11201806338SA (enExample) |
| WO (1) | WO2017136492A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018217659A1 (en) * | 2017-05-22 | 2018-11-29 | Oncoimmune, Inc. | Methods of use of soluble cd24 for treating immune related adverse events in cancer therapies |
| SG11202007815TA (en) * | 2018-03-05 | 2020-09-29 | Oncoimmune Inc | Methods of use of soluble cd24 for treating acquired immune deficiency syndrome (hiv/aids) |
| WO2019236474A1 (en) | 2018-06-04 | 2019-12-12 | Oncoimmune, Inc. | Methods of use of cd24 for the prevention and treatment of leukemia relapse |
| US20220000974A1 (en) * | 2019-02-06 | 2022-01-06 | Oncolmmune, Inc. | Targeting CD24-Siglec Interactions for Treating Subjects with Prediabetes or Diabetes |
| WO2020163529A1 (en) * | 2019-02-06 | 2020-08-13 | Oncoimmune, Inc. | Targeting cd24-siglec interactions for the treatment and prevention of nonalcoholic steatohepatitis |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001259792B2 (en) * | 2000-03-29 | 2005-12-22 | The Ohio State University Research Foundation | Methods of blocking tissue destruction by autoreactive T cells |
| WO2004106495A2 (en) * | 2003-05-29 | 2004-12-09 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer |
| JP5899206B2 (ja) * | 2010-04-28 | 2016-04-06 | オンコイミューン， インコーポレイテッド | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
| JP6116568B2 (ja) | 2011-08-30 | 2017-04-19 | アカデミッシュ メディッシュ セントラム | インスリン抵抗性を予防および／または処置する方法 |
| HK1214628A1 (zh) * | 2012-11-05 | 2016-07-29 | Pronai Therapeutics, Inc. | 寡核苷酸癌症療法的給藥和施用 |
-
2017
- 2017-02-02 WO PCT/US2017/016120 patent/WO2017136492A1/en not_active Ceased
- 2017-02-02 SG SG11201806338SA patent/SG11201806338SA/en unknown
- 2017-02-02 JP JP2018539976A patent/JP6938835B2/ja not_active Expired - Fee Related
- 2017-02-02 US US16/074,726 patent/US10799558B2/en not_active Expired - Fee Related
- 2017-02-02 KR KR1020187022125A patent/KR20180120145A/ko not_active Ceased
- 2017-02-02 EP EP17748111.6A patent/EP3411062B1/en active Active
- 2017-02-02 CA CA3012466A patent/CA3012466A1/en not_active Abandoned
- 2017-02-02 CN CN201780008474.2A patent/CN109069583B/zh not_active Expired - Fee Related
-
2020
- 2020-10-12 US US17/067,929 patent/US20210162006A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA3012466A1 (en) | 2017-08-10 |
| CN109069583B (zh) | 2021-09-21 |
| EP3411062B1 (en) | 2020-11-25 |
| JP2019506408A (ja) | 2019-03-07 |
| WO2017136492A1 (en) | 2017-08-10 |
| US20190038716A1 (en) | 2019-02-07 |
| JP6938835B2 (ja) | 2021-09-22 |
| US10799558B2 (en) | 2020-10-13 |
| EP3411062A1 (en) | 2018-12-12 |
| EP3411062A4 (en) | 2019-09-25 |
| US20210162006A1 (en) | 2021-06-03 |
| SG11201806338SA (en) | 2018-08-30 |
| CN109069583A (zh) | 2018-12-21 |
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