KR20180113078A - Container for preserving tissue - Google Patents

Abstract

The present invention relates to a tissue preserving container, comprising: a body which opens an upper part thereof and forms a space accommodating a tissue and a fixation solution therein; a cover which is able to be coupled to the upper part of the body; a lower plate which has a first through-hole vertically penetrated, and is mounted and coupled to the inside of the body to be able to rotate by coming into close contact with an inner circumferential surface of the body; an upper plate which has a second through-hole corresponding to the first through-hole, and forms a plurality of protruding pieces away from each other at a predetermined distance along an outer side in an upper part thereof, and is mounted on an upper side of the lower plate to be able to rotate; a protrusion which protrudes downwardly to be inserted into a space between the protruding pieces in the inner surface of the cover; and a through-hole location adjusting means which adjusts locations of the first through-hole and the second through-hole to be matched or not to be matched with each other according as the upper plate is interlocked and rotated when the cover is rotated by a coupling of the protrusion and the protruding piece. The purpose of the present invention is to provide a tissue preserving container which blocks pungent odor of a fixation liquid accommodated in a tissue preserving container and prevents the fixation liquid from being leaked.

Description

[0001] Container for preserving tissue [0002]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a tissue preservation container, and more particularly, to a tissue preservation container that prevents smell of a fixation solution contained in a tissue preservation container and prevents the fixation solution from flowing out of the container.

The tissue collected from the patient's lesion is an important resource in the diagnosis, treatment, research, and development of new drugs. In order to accurately diagnose and treat the disease, and to study it, Most of which is carried to a location where there is inspection equipment for observation and analysis, with the tissue taken from the patient's lesion in a container.

At this time, the tissue contained in the container is stored in the container, may be moved for a short period of time for inspection of the tissue, and in some cases, long-distance movement may be inevitable, and the current storage and transportation of tissues A container of a cylindrical body having a storage space of a tissue is simply used.

The conventional tissue preservation container currently in use is composed of a body and a lid. The tissue collected from the patient's lesion is put into the body and a fixer is put in order to preserve the state of the tissue. In this case, The tissue or cell is kept in a state as it was at the time of collection, and the structure or cell structure is left in a state suitable for observation, analysis, and specimen production.

The fixation solution for fixation is to penetrate into tissues and fix tissues to preserve tissues so that they are not decomposed any more and are kept in a collected state. Usually, formalin is mainly used, and various kinds of drugs . It may be fixed with a single drug but it may be changed in form. Therefore, two or more kinds of drugs may be mixed and used. For fixation of plant tissues and diseased tissues, formalin-acetic acid-alcohol fixer is most widely used.

In particular, formalin is one of the most hazardous chemicals because it has a coagulation action and a polymerization action of protein, and thus is used as an excellent fixing solution or a material thereof. However, formalin is one of harmful chemicals, and formaldehyde prepared by oxidizing methyl alcohol is dissolved in a concentration of 37% It is an aqueous solution dissolved in water. It is known to be toxic and has a strong irritating odor, and it is known that its toxicity is 5 times stronger than that of phenol.

Especially, when the human is exposed to gaseous formaldehyde because of its strong toxicity to the human body, strong protein coagulation action invades the skin or mucous membrane. If a large amount of formalin is inhaled, it becomes a central nervous system disorder, shock, and coma , And high doses can lead to heart failure and death.

In addition, formalin is not decomposed and is known to seriously threaten ecosystems in the water when it flows into rivers. In Korea, strict management is carried out in accordance with the Water Quality and Ecosystem Conservation Act and the Toxic Chemicals Control Act.

Therefore, when a fixer containing harmful components such as formalin is used to preserve tissues or cells, the conventional tissue preservation container is composed of a body and a lid, and is likely to be exposed to a harmful ingredient when the tissue is put into a container, The operation process of the user is not comfortable due to the irritating odor of the user, and serious damage occurs when the fixing liquid is leaked.

Therefore, it is necessary to develop a tissue preservation vessel that can block the smell of the fixative and prevent damages caused by the fixative solution containing harmful components.

Korean Patent Laid-Open Publication No. 10-2016-0094454 (publication date: 2016.02.03)

SUMMARY OF THE INVENTION The present invention has been conceived to solve the problems described above, and it is an object of the present invention to provide a tissue preservation container which can prevent the irritating odor of the fixation solution contained in the tissue preservation container and prevent the fixation solution from flowing out of the container The purpose.

[0001] The present invention relates to a tissue preservation container, which comprises a body having an upper opening and a space for receiving tissue and fixation fluid therein, a lid formed to be engageable with an upper portion of the body, And a second through hole corresponding to the first through hole is formed. The upper plate is spaced apart from the outer side by a predetermined distance, and a plurality of latching pieces An upper plate rotatably seated on the lower plate, an engaging protrusion protruded downward to be inserted into the space between the plurality of engaging pieces on the inner surface of the lid, and an engaging protrusion formed on the inner surface of the lid, The position of the first through hole and the second through hole can be adjusted by rotating the upper plate interlockingly with rotation And a through-hole position adjusting means for adjusting the mutually aligned states or mutually shifted states.

In this case, the through-hole position adjusting means includes an arcuate guide groove formed on one side of the lower plate and the upper plate, and a guide protrusion protruding from the other side of the lower plate and the upper plate to be inserted into the guide groove, And a control unit.

When a plurality of the first through holes are formed and the plurality of first through holes are spaced apart from each other at a predetermined distance and radially disposed, the arc forming angle R of the guide groove is obtained by the following equation .

(Where R denotes the arc forming angle of the guide groove, and n denotes the number of the first through holes).

The upper plate may have a seating groove on which the upper plate is seated, and an inner circumferential surface of the seating groove may have a fitting groove into which the outer plate is inserted.

According to the tissue preservation container of the present invention, when the lid is rotated by the engaging protrusion formed on the inner surface of the lid and the engagement of the engaging pieces formed on the upper plate, the upper plate is rotated to be rotated and the position of the first through- The first through hole and the second through hole are automatically aligned in the process of joining the body and the lid so that the first through hole and the second through hole are aligned with each other, The first through-hole and the second through-hole can be automatically shifted from each other in the process of separating the body and the lid, thereby closing the first through-hole, thereby separating the body and the lid The irritating odor of the fixing liquid can be blocked and the fixing liquid can be prevented from flowing out to the outside, There is an effect capable of improving the business environment.

In addition, when the fixing liquid contained in the tissue preservation container contains harmful components such as formalin, the first through-hole is automatically closed when the body and the lid are separated, so that the damage caused by the leakage of the fixative containing the harmful component to the outside Can be prevented.

1 is an exploded perspective view showing a tissue storage container according to an embodiment of the present invention.
2 is an exploded cross-sectional view of a tissue storage container according to an embodiment of the present invention.
3 is a cross-sectional view of a tissue storage container according to an embodiment of the present invention.
FIG. 4 is a plan view, a front view, and a bottom view of a bottom plate according to an embodiment of the present invention.
5 is a plan view, front view, and bottom view of an upper plate according to an embodiment of the present invention.
FIG. 6 is an exemplary view illustrating a state in which a first through hole of a tissue storage container according to an embodiment of the present invention is opened as a bottom view of a lower plate. FIG.
FIG. 7 is an exemplary view showing a state in which a first through hole of a tissue storage container according to an embodiment of the present invention is closed, as a bottom view of a lower plate. FIG.
8 is a bottom view of a bottom plate of a tissue storage container according to an embodiment of the present invention in which a first through hole is closed.
FIG. 9 is an exemplary view showing a coupling structure of a lower plate and an upper plate according to the present invention. FIG.

The tissue preservation container according to the present invention is configured to prevent the irritating odor of the fixation solution contained in the tissue preservation container and to prevent the fixation solution from leaking to the outside. The tissue preservation container includes a body, a lid, a lower plate, Wherein the upper plate and the lower plate are coupled to each other and the upper plate and the lower plate are coupled to each other, A space for receiving the fixing liquid is formed below the position where the upper plate is formed, and a space for receiving the tissue to be inspected is formed on the upper side.

In this case, a first through-hole is formed in the lower plate, and a second through-hole is formed in the upper plate so as to correspond to the first through-hole. A plurality of latching pieces are formed at predetermined intervals along the upper outer side, A locking protrusion formed to protrude downward to be inserted into a space between the plurality of locking pieces is formed. When the lid is rotated to engage the body and the lid, the upper plate is rotated by interlocking with the lid by engagement of the locking protrusion and the locking piece, And the through holes are opened or closed by the through hole position adjusting means for adjusting the positions of the first through holes and the second through holes so as to be mutually coincident or mutually shifted.

In this way, in the tissue preservation container according to the present invention, the first through hole is automatically opened or closed in the process of joining or separating the body and the lid by the through hole position adjusting means, and the state is continuously maintained .

Hereinafter, the technical idea of the present invention will be described more specifically with reference to the accompanying drawings.

BRIEF DESCRIPTION OF THE DRAWINGS The accompanying drawings, which are included to provide a further understanding of the technical concept of the present invention, are incorporated in and constitute a part of the specification, and are not intended to limit the scope of the present invention.

FIG. 1 is an exploded perspective view showing a tissue preservation container according to an embodiment of the present invention, FIG. 2 is an exploded sectional view showing a tissue preservation container according to an embodiment of the present invention, FIG. Fig.

1 to 3, a tissue storage container according to an embodiment of the present invention includes a body 100, a lid 200, a lower plate 300, an upper plate 400, a locking projection 500, And a through hole position adjusting means (600).

First, the body 100 is formed into a cylindrical structure having an opened top surface, and a fixation liquid for retaining tissues and tissues is accommodated therein. In this case, the fixing liquid may be an aqueous formalin solution, but the present invention is not limited thereto.

Next, the lid 200 is configured to engage with the upper portion of the body 100 to cover the upper portion of the body 100.

In this case, the body 100 is formed with threads on the outer circumferential surface, and the lid 200 is formed with threads on the inner circumferential surface thereof so that the body 100 and the lid 200 can be screwed together. However, the present invention is not limited thereto A screw thread is formed on the upper inner peripheral surface of the body 100 and a screw thread is formed on the outer peripheral surface of the lid 200 so that the body 100 and the lid 200 can be screwed together, And the lid 200 can be coupled by rotation, any coupling structure is possible.

FIG. 4 is a plan view, a front view, and a bottom view of a bottom plate according to an embodiment of the present invention.

4, the lower plate 300 is in close contact with the inner circumferential surface of the body 100 and rotatably seated in the body 100. More specifically, the outer circumferential surface of the lower plate 300 is coupled to the body 100 100 to be fixed to the inner surface of the body 100 so as to be rotatable along the inner circumferential surface of the body 100 when an artificial force of a predetermined magnitude or more is applied thereto.

In addition, the lower plate 300 may have a first through hole 310 penetrating in the vertical direction, and the first through hole 310 may be formed of one or more than two, and as shown in FIG. 4, When a plurality of first through holes 310 are formed, the plurality of first through holes 310 are spaced apart from each other by a predetermined distance, and the plurality of first through holes 310 are radially arranged about the center of the lower plate 300.

5 is a plan view, front view, and bottom view of an upper plate according to an embodiment of the present invention.

5, the upper plate 400 is formed with a second through hole 410 corresponding to the first through hole 310, and has a plurality of retaining pieces 420 And is rotatably seated on the upper plate 300.

In this case, the second through hole 410 preferably has a number and a shape corresponding to the first through hole 310. When the upper plate 400 is seated on the lower plate 300 and rotated, The first through hole 310 is opened or closed so that the inside of the body 100 is connected to the lower plate 300 and the upper plate 400, So that the lower space and the upper space of the upper space are communicated or disconnected.

The locking protrusions 500 are for rotating the upper plate 400 when the lid 200 is rotated and are rotatably supported on the inner surface of the lid 200 by a plurality of locking pieces 420 And the locking protrusions 500 may be formed of one or more than two.

1 to 3, when the locking protrusion 500 is provided, the locking protrusion 500 and the locking protrusion 420 are inserted into any one of the spaces between the locking protrusions 420, The lid 200 and the body 100 are coupled to each other by the engaging projection 500 and the engaging piece 420 being engaged with each other so that the lid 200 is rotated, The upper plate 400 is rotated to rotate.

The second through holes 410 formed in the upper plate 400 may be aligned with or offset from the first through holes 310 formed in the lower plate 300 as the upper plate 400 rotates, The first through hole 310 is opened and closed.

The through hole position adjusting means 600 adjusts the positions of the first through holes 310 and the second through holes 410 as the upper plate 400 rotates in conjunction with rotation of the lid 200, And may include a guide groove 610 and a guide protrusion 620 as shown in FIGS. 1 to 5, and the guide groove 610 may be formed in a lower plate And the guide protrusion 620 is protruded toward the guide groove 610 at the lower portion of the upper plate 400 and inserted into the guide groove 610 so that the upper plate 400 is rotated The guide groove 610 is formed as an arc-shaped through hole in the lower plate 300. However, the guide groove 610 may be formed in a circular arc concave shape It is possible.

When the guide protrusion 620 and the guide protrusion 620 are brought into contact with the one side of the guide groove 610, the guide protrusion 620 and the guide groove 610 are in contact with the first through hole 310 of the lower plate 300, When the guide protrusion 620 is brought into contact with the other side of the guide groove 610, the first through hole 310 of the lower plate 300 and the second through hole 410 of the lower plate 300 are aligned with each other. The positions of the first through holes 310 and the second through holes 410 are set such that the second through holes 410 of the upper plate 400 are positioned to be shifted from each other, So that they can be adjusted to be in a matched state or mutually shifted state to maintain the state.

The guide groove 610 is formed in the upper plate 400 and the guide protrusion 620 is protruded toward the guide groove 610 on the upper portion of the lower plate 300, The position of the guide groove 610 in which the upper plate 400 is formed is changed as the upper plate 400 is rotated. In this case, the lower plate 300 The first through hole 310 of the lower plate 300 and the second through hole 410 of the upper plate 400 coincide with each other by contacting one side of the guide groove 610 to the guide protrusion 620 formed on the lower plate 300 And the other side of the guide groove 610 abuts against the guide protrusion 620 formed on the lower plate 300 so that the first through hole 310 of the lower plate 300 and the second through hole 310 of the upper plate 400, Holes 410 are formed so as to be shifted from each other, Plate portion 400 is adjusted as the rotation positions of the first through hole 310 and the second through hole 410 to match the cross-state or inter-state to be shifted so as to maintain the condition.

The process of opening and closing the first through hole 310 in the tissue preservation container according to the embodiment of the present invention will be described as follows.

First, in the tissue preservation container according to the first embodiment of the present invention, a plurality of retaining pieces 420 are spaced apart from each other at an upper portion of the upper plate 400 which is seated inside the body 100, A locking protrusion 500 protruded downward to be inserted into and coupled with the space between the plurality of locking pieces 420 is formed inside the body 100 so that the locking protrusion 500 is seated in the body 100 in the course of coupling the body 100 and the lid 200 The engaging pieces 420 may be engaged with the engaging protrusions 500 by inserting the engaging protrusions 500 into a space between the plurality of engaging pieces 420 formed on the upper plate 400, An example of the coupling structure of the coupling member 500 can be confirmed with reference to FIG.

As the lid 200 is rotated by the engagement structure of the engaging piece 420 and the engaging protrusion 500, the upper plate 400 rotates in conjunction with the rotation of the upper plate 400, The second through hole 410 of the upper plate 400 and the first through hole 310 of the lower plate 300 coincide or are shifted from each other so that the first through hole 310 is opened and closed.

Hereinafter, the process of opening the first through hole 310 by coupling the body 100 with the lid 200 will be described in more detail.

FIG. 6 is an exemplary view illustrating a state in which a first through hole of a tissue storage container according to an embodiment of the present invention is opened as a bottom view of a lower plate. FIG.

6, the state in which the first through hole 310 is opened refers to a state in which the positions of the first through hole 310 and the second through hole 410 coincide with each other, When the upper plate 400 is rotated in the direction in which the lid 200 is rotated by interlocking with the lid 200 by the coupling structure of the engaging piece 420 and the engaging projection 500 in the process of coupling the lid 200, The guide protrusion 620 formed at the lower portion of the upper plate 400 moves along the circular guide groove 610 formed in the lower plate 300 in the direction in which the lid 200 rotates, The guide protrusion 620 is brought into contact with the end of the lid 200 in the direction in which the lid 200 is rotated so that the first through hole 310 and the second through hole 410 can be kept in a state in which they are aligned with each other.

When the first through-hole 310 and the second through-hole 410 coincide with each other and the first through-hole 310 is opened, the body 100 and the lid 200 are not completely coupled In this case, when the lid 200 is further rotated to completely engage the body 100 and the lid 200, a guide protrusion (not shown) is formed on the end of the guide groove 610 in the direction in which the lid 200 is rotated The upper plate 400 and the lower plate 300 rotate at the same time while the first through hole 310 is kept open by the force of the user rotating the lid 200 The body 100 and the lid 200 are fully engaged.

In the process of coupling the body 100 and the lid 200 as described above, the guide hole 610 and the guide protrusion 620, which are the through-hole position adjusting means 600, The first through hole 310 is kept open when the body 100 and the lid 200 are coupled to each other, The fixing liquid contained in the lower plate 300 is moved upward through the first through hole 310 to the upper side of the upper plate 400 so that the fixing liquid is supplied to the upper side of the upper plate 400, Contact with each other.

The process of closing the first through hole 310 by separating the body 100 and the lid 200 will now be described in more detail. In this case, the separation process between the body 100 and the lid 200 It is preferable that the tissue preservation vessel is moved after the lid 200 is positioned to face upward and the fixation liquid is moved in the downward direction of the lower plate 300.

FIG. 7 is an exemplary view showing a state in which a first through hole of a tissue storage container according to an embodiment of the present invention is closed, as a bottom view of a lower plate. FIG.

7, the state in which the first through hole 310 is closed refers to a state in which the positions of the first through hole 310 and the second through hole 410 are shifted, and the body 100 and the lid The upper plate 400 is interlocked with the lid 200 by the engagement structure of the engaging piece 420 and the engaging projection 500 in the process of separating the lid 200 from the lid 200, The guide protrusion 620 formed at the lower portion of the upper plate 400 is rotated in the direction of the arrow A in the lower portion of the upper plate 400 when the first through hole 310 is rotated in a direction opposite to the rotation direction in the process of opening the first through hole 310. [ The lid 200 moves in a direction in which the lid 200 is rotated along the arc-shaped guide groove 610 formed in the plate 300. At this time, the guide protrusion 620 The positions of the first through holes 310 and the second through holes 410 can be maintained to be displaced from each other.

When the first through-hole 310 and the second through-hole 410 are shifted from each other and the first through-hole 310 is closed, the body 100 and the lid 200 are completely separated from each other In this case, when the lid 200 is further rotated to completely separate the body 100 and the lid 200, the guide groove 610 is provided with a guide (not shown) The upper plate 400 and the lower plate 300 are rotated simultaneously while the first through holes 310 are kept closed by the force of the user rotating the lid 200 since the protrusions 620 are in contact with each other, And the body 100 and the lid 200 are completely separated from each other.

In the process of separating the body 100 and the lid 200 from each other, the guide hole 610 and the guide protrusion 620, which are the through-hole position adjusting means 600, The first through hole 310 is maintained in a closed state when the body 100 and the lid 200 are separated from each other, When the container body 100 and the lid 200 are separated from each other, the fixation liquid accommodated in the lower side of the lower plate 300 is prevented from flowing out, thereby preventing damage caused by the outflow of the fixation liquid.

When the body 100 and the lid 200 are separated from each other, the first through-hole 310 is maintained in a closed state, so that the fixing liquid stored under the lower plate 300 flows out to the upper side of the lower plate 300 Which can prevent the user's working environment from being contaminated, and can prevent damages caused by harmful components when the fixing liquid contains harmful components, and it is made of ingredients having irritating odor such as formalin The smell of the fixing liquid is blocked, so that there is an effect that the working environment of the user can be maintained more comfortably.

8 is a bottom view of the bottom plate of the tissue storage container according to the embodiment of the present invention in which the first through hole is closed.

As shown in FIG. 8, when a plurality of first through holes 310 are formed and a plurality of first through holes 310 are radially disposed at a predetermined distance from each other, At this time, the arcuate forming angle of the guide groove 610 may be such that the upper plate 400 is rotated left and right in a state where the lower plate 300 is fixed The guide groove 610 should be formed outside the outer periphery of the first through hole 310 from the center of the upper plate 400 as shown in FIG.

Here, R denotes the arc forming angle of the guide groove, and n denotes the number of the first through holes.

Referring to FIG. 8, the arc forming angles of the guide grooves 610 will be described in more detail as follows.

As shown in FIG. 8, when the number of the first through holes 310 is two, it is preferable that the arc forming angle of the guide groove 610 is formed to be 90 degrees by the above formula. In the case where the two first through holes 310 formed in the lower plate 300 are spaced apart from each other with reference to the center of the lower plate 300 and radially disposed, Symmetrically positioned at an angle of 180 deg., Which is an angle obtained by dividing the number of the first through holes 310 by 360, with respect to the center of the lower plate 300. [

At this time, when the second through hole 410 is rotated in a state of being displaced from the position of the first through hole 310 while the positions of the first through hole 310 and the second through hole 410 coincide with each other, When the second through hole 410 is moved in a rotationally symmetrical position by a half size of 180 ° which is the angle obtained by dividing the number of the first through holes 310 by 360 °, The second through holes 410 can be positioned at the most distant positions from the first through holes 310. Therefore, the second through holes 410 can be positioned at the most distant positions from the first through holes 310, will be.

Therefore, the guide groove 610 and the guide protrusion 620 are formed, and the circular arc forming angle of the guide groove 610 is 180 ° which is an angle obtained by dividing the number of the first through holes 310 by 360 The second through hole 410 completely overlaps with the first through hole 310 and the second through hole 410 completely coincides with the upper plate 400 in a state where the lower plate 300 is fixed, Can be adjusted to a position most distant from the first through hole 310, so that the first through hole 310 can be completely opened or closed.

The first through hole 310 and the second through hole 410 are automatically aligned with each other when the body 100 and the lid 200 are coupled to each other, The first through hole 310 can be opened so that the first through hole 310 and the second through hole 410 are automatically positioned in the process of separating the body 100 and the lid 200 from each other So that the first through hole 310 can be closed.

In addition, in the tissue preservation container according to the present invention, the coupling structure between the body 100 and the lower plate 300 is such that the outer surface of the lower plate 300 is in close contact with the inner peripheral surface of the body 100, A coupling structure between the body 100 and the lower plate 300 will be described in more detail as follows.

As a first embodiment of the coupling structure between the body 100 and the lower plate 300, the body 100 is formed in a cylindrical structure having an opened upper surface. As the circumferential size of the body 100 decreases from the upper side to the lower side The circumferential size of the inner circumferential surface of the body 100 and the circumferential size of the outer circumferential surface of the lower plate 300 coincide with each other in the body 100, The outer circumferential surface of the lower plate 300 may be formed so as to be reduced in size from the upper side to the lower side, and the circumferential size of the outer circumferential surface of the lower plate 300 may be smaller than the circumferential size of the outer circumferential surface of the lower plate 300 It is preferable that the degree of reduction is formed to coincide with the degree of reduction of the circumferential size of the body 100.

The second embodiment of the coupling structure between the body 100 and the lower plate 300 includes a support protrusion 110 protruding inwardly from the body 100 along the inner circumferential surface of the body 100, The lower plate 300 may be seated and supported on the upper portion of the protrusion 110 so that the lower plate 300 may be seated in the body 100. When the support protrusions 110 are formed in plural The plurality of support protrusions 110 are spaced apart from each other by a predetermined distance and are arranged in a radial configuration about the center of the body 100 to stably support the lower plate 300.

In addition, the coupling structure between the body 100 and the lower plate 300 may be formed by a combined structure using the combination of the first and second embodiments.

FIG. 9 is an exemplary view showing a coupling structure of a lower plate and an upper plate according to the present invention. FIG.

9, a tissue storage container according to the present invention includes a lower plate 300 having a seating groove 320 on which an upper plate 400 is seated, The upper plate 400 and the lower plate 300 are prevented from being separated from the lower plate 300 by preventing the upper plate 400 and the lower plate 300 from being separated from each other, As shown in FIG.

It will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.

100: Body
110: support projection
200: Lid
300: Lower plate
310: first through hole
320: seat groove
330: Fitting groove
400: upper plate
410: second through hole
420:
500:
600: through hole positioning means
610: Guide groove
620: guide projection

Claims (4)

A body having a top opened and a space in which a tissue and a fixing liquid are received,
A lid formed to be engageable with an upper portion of the body,
A lower plate formed with a first through-hole penetrating in a vertical direction, a lower plate closely fitted to the inner circumferential surface of the body and rotatably seated in the body,
An upper plate rotatably seated on the lower plate, a plurality of second engaging pieces formed on the upper plate at predetermined intervals along the outer side,
An engaging protrusion protruding downward to be inserted into the space between the plurality of engaging pieces on the inner surface of the lid,
A through hole position adjusting means for adjusting the positions of the first through holes and the second through holes to mutually coincide or mutually offset as the upper plate is rotated and rotated when the lid is rotated by the engagement of the engaging protrusion and the engaging pieces, Wherein the tissue storage container comprises:
The method according to claim 1,
The through-hole position adjusting means
An arc-shaped guide groove formed at one side of the lower plate and the upper plate,
And a guide projection protruding from the other of the lower plate and the upper plate toward the guide groove and inserted into the guide groove.
3. The method of claim 2,
Wherein the first through holes are formed in a plurality of the first through holes,
Wherein an arc forming angle (R) of the guide groove is obtained by the following equation.

(Where R denotes the arc forming angle of the guide groove, and n denotes the number of the first through holes).
4. The method according to any one of claims 1 to 3,
The lower plate
A seating groove on which the upper plate is seated is formed on an upper portion thereof,
Wherein the fitting groove is further formed in an inner circumferential surface of the seating groove, into which an outer rim of the upper plate is inserted.

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