KR200489217Y1 - Container for tissue samples - Google Patents

Container for tissue samples Download PDF

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Publication number
KR200489217Y1
KR200489217Y1 KR2020190000496U KR20190000496U KR200489217Y1 KR 200489217 Y1 KR200489217 Y1 KR 200489217Y1 KR 2020190000496 U KR2020190000496 U KR 2020190000496U KR 20190000496 U KR20190000496 U KR 20190000496U KR 200489217 Y1 KR200489217 Y1 KR 200489217Y1
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KR
South Korea
Prior art keywords
tissue sample
storage compartment
container
fixing
sealing material
Prior art date
Application number
KR2020190000496U
Other languages
Korean (ko)
Inventor
강성국
Original Assignee
(주) 메디포유
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by (주) 메디포유 filed Critical (주) 메디포유
Priority to KR2020190000496U priority Critical patent/KR200489217Y1/en
Application granted granted Critical
Publication of KR200489217Y1 publication Critical patent/KR200489217Y1/en

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Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0236Mechanical aspects
    • A01N1/0263Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
    • A01N1/0273Transport containers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0689Sealing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/042Caps; Plugs
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/044Connecting closures to device or container pierceable, e.g. films, membranes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/046Function or devices integrated in the closure
    • B01L2300/047Additional chamber, reservoir
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0672Integrated piercing tool

Abstract

The present invention relates to a tissue specimen container comprising an outer tube having a bottom surface of an inner space formed with a sealing member breakage protrusion and an outer thread formed on an outer surface of an upper end portion; A lower liquid storage compartment is formed around the periphery of the seal body, a lower liquid storage compartment is formed around the periphery of the seal body, A plurality of fixing fluid inflow holes formed on the bottom surface of the tissue sample storage part so as to allow the fixing fluid discharged from the fixing fluid storage compartment to flow therethrough; A sealing material attached to a lower surface of the inner cylinder in a state where the fixing liquid is introduced into the fixing liquid storage compartment of the inner cylinder to seal the fixing liquid storage compartment; And a cap body having an internal thread for engaging with the outer tube, the container body being provided with a container lid for pushing and pressing the inner tube upon rotation by thread engagement of the outer passage to rotate and pull the lid.
According to the present invention, when the container lid is threadedly coupled to the outer cylinder, the inner cylinder is pulled up and down, and the sealant is broken due to forcible contact with the sealing material breakage protrusion of the outer cylinder, and the fixation liquid stored in the fixation liquid storage compartment is discharged, The tissue specimen storage part is filled and filled with the tissue specimen and the fixing solution.

Description

{CONTAINER FOR TISSUE SAMPLES}

The present invention relates to a tissue specimen container, and more particularly, to provide a new structure and method for filling a tissue specimen with a fixer solution by using a sealing material structure to break the sealing material, The present invention relates to a tissue specimen container which can reduce the labor and time required for removing a tissue specimen by reducing the work process for removing the specimen.

In general, tissue specimen containers are used to hold tissue specimens collected from diseased sites in medical institutions or public health centers, including clinics, to determine the presence or absence of germs. Such specimens are used for accurate diagnosis, In order to do this, it is necessary to carry out observation and analysis.

The tissue sample container is filled with a liquid content such as a formalin fixer or the like so that the tissue sample can be preserved or stored for a long period of time. The lid is filled so as not to leak, Which is not decomposed any longer and is kept in a harvested state.

However, most of the currently used tissue sample containers suffer from the problem that the tweezers come into contact with the fixer when the tissue specimen contained in the fixer is taken out by the examinee, and it takes a long time because many work processes for separating the tissue specimen from the fixer are performed It is troublesome and inconvenient, and the improvement is demanded.

In addition, there is a problem in that it takes more time than necessary to perform an inspection due to a work requiring a large number of procedures, such as transferring a tissue sample taken out from a tissue sample container to a tissue cassette for easy inspection there was.

In particular, in conventional tissue sample containers, when the container is tilted or the position is turned upside down by inserting a tissue specimen and a fixer, the tissue specimen and fixer are separated from each other. As a result, the tissue specimen is not fixed, There is a problem that it can not be done.

In addition, the conventional tissue sample containers have difficulties in solving the above-mentioned problems, and in many cases, they are inconvenient to use due to the increase in the size of the container or the complication of the structure in order to provide functionality.

The applicant of the present application has made efforts to improve many problems occurring in the field with respect to the tissue specimen container, proposed a tissue specimen transport container through Korean Patent Registration No. 10-1624962, 10-1823438 proposes a tissue sample transport container having an automatic filling and external exposure prevention structure of fixation liquid and recently proposed a new method for solving the problems newly introduced in the case of using the tissue sample container as described above .

Korean Patent Publication No. 10-1624962 Korean Patent Publication No. 10-1823438

The present invention has been made in view of the above-mentioned problems of the related art, and it is intended to implement a new structure and method for infiltrating and filling the fixation liquid into the tissue specimen through the breakage of the sealing material by applying the sealing material structure, And to provide a tissue sample container that can simplify and reduce the work process for taking out and using tissue samples.

The present invention provides a tissue sample container which is filled with a fixing fluid through a structure to improve the structure and is filled in a manner to have a moving flow on an empty space and can maintain a stable fixed state with respect to a tissue sample. .

The present invention relates to a method of separating a tissue specimen and a fixing solution from each other when the container is tied and fixed in a tissue specimen and the specimen is tilted up and down and the tissue specimen is not fixed, It is an object of the present invention to provide a tissue sample container in which a tissue sample and a fixer solution are always mixed in any state to maintain a fixed state.

It is an object of the present invention to provide a tissue sample container in which an examiner can improve the problem that the tweezers come into contact with the fixer when the tissue sample contained in the fixer is taken out.

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In order to achieve the above object, a tissue sample container according to an embodiment of the present invention includes a tissue sample collected from a lesion site of a patient, a fixation liquid as a liquid content for charging the tissue sample through fixation and for long- And a tissue sample container which can be stored together with a tissue sample, wherein the outer tube has a sealing material breakage protrusion formed on a bottom surface of the inner space and an outer thread is formed on an outer surface of an upper end portion; A lower liquid storage compartment is formed around the periphery of the seal body, a lower liquid storage compartment is formed around the periphery of the seal body, A plurality of fixing fluid inflow holes are formed on the bottom surface of the tissue sample storing part to allow the fixing fluid discharged from the fixing fluid storage compartment to flow in an external force; A sealing member attached to the lower surface of the inner cylinder in a state where the fixing solution is introduced into the fixing solution storage compartment of the inner tube, the sealing member sealing the fixing solution storage compartment; A cap body having an internal thread for engaging with the outer tube, the container lid being configured to press and push the inner tube upon rotation due to thread engagement of the outer thread to rotate and pull down, The sealant is torn and broken due to contact with the sealing material breakage protrusion of the outer tube when the inner tube is pulled up and down, and the fixation solution stored in the fixation solution storage compartment is discharged and charged into the tissue specimen storage part through the fixation solution inflow hole, And the stored tissue sample and fixation solution are mixed.

In this case, the inner cylinder is provided with a rotation and descent induction protrusion protruding from the upper surface of the edge having the closed structure of the fixation liquid storage compartment, and the container lid is formed with a rotating and descending pull protrusion protruding from the inner edge thereof; When the container lid is threadedly coupled to the outer cylinder, the container lid side rotating and lowering pulling projections pull the inner cylinder side rotating and lowering inducing projections to rotate and lower the inner tube, thereby forcibly contacting the sealing material to the sealing failure projection side to break the sealing material .

Here, the bottom surface of the tissue specimen storage portion having the fixer solution inflow hole is formed to be located above the lower surface of the inner tube, so that the flow of the fixer solution is not clogged according to the fluid flow and movement principle, Can be configured.

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According to the present invention, when the container lid is threadedly coupled to the outer cylinder, the inner cylinder is pulled up and down, and the sealant is torn and broken due to contact with the sealing material breakage protrusion of the outer cylinder, whereby the fixation liquid stored in the fixation liquid storage compartment is discharged, And the tissue specimen stored therein may be mixed with the fixer.

According to the present invention, when the container is filled with a fixative solution in a tissue sample and the container is tilted or turned upside down, there is a problem that the tissue sample and the fixative liquid are separated from each other and the tissue sample is not fixed, So that the tissue sample and the fixative solution can always be mixed in any state to maintain the fixation state well.

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The present invention also provides a new structure and method for infiltrating and immobilizing the fixative fluid into the tissue sample through breakage of the sealing material, simplifying and reducing the work process for the user to take out tissue samples, When the specimen is filled with the specimen, the specimen is filled in a manner such that it has a flow of movement to the void space. The specimen can be held in a stable state with respect to the specimen. When the specimen is taken out of the fixer, The problem can be solved.

1 is an exploded perspective view showing a tissue sample container according to one embodiment of the present invention.
FIG. 2 is an exploded perspective view showing a tissue sample container according to an embodiment of the present invention in another direction. FIG.
3 is a sectional exploded view showing a tissue sample container according to one embodiment of the present invention.
FIG. 4 is a state view showing a tissue sample container according to an embodiment of the present invention, wherein FIG. 4 (a) is a view showing a state in which an inner tube is inserted and disposed in the outer tube, To fix the tissue specimen.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, preferred embodiments of the present invention will be described with reference to the accompanying drawings. The present invention will become more apparent from the following detailed description when taken in conjunction with the accompanying drawings.

The tissue sample container 100 according to one embodiment of the present invention includes a tissue sample collected from a lesion site of a patient, and a liquid fixation solution for charging the tissue specimen and preserving the tissue sample for a long period of time, 1 to 4, the container 100 includes an outer cylinder 110, a inner cylinder 120, a sealant 130, and a container lid 140. The outer cylinder 110, the inner cylinder 120,

The outer cylinder 110 has a cylindrical body having an open top structure. The outer cylinder 110 has a sealing member breakage protrusion 111 protruding from the bottom surface of the inner space. An outer thread 112 is formed on the outer surface of the top end.

The inner cylinder 120 is inserted into the inner space of the outer cylinder 110 and is inserted into the inner space of the outer cylinder 110, A fixed liquid storage compartment 121 which is initially positioned in a noncontacted state on the upper side and descendable when an external force is applied, a lower liquid storage compartment 121 is opened around the periphery, and a tissue A plurality of fixing fluid inflow holes 123 are formed in the bottom surface of the tissue sample storage part 122 so that the fixing fluid discharged from the fixing fluid storage compartment 121 can be introduced into the sample storage part 122 .

At this time, the inner cylinder 120 is provided with a rotation and descent induction protrusion 124 protruding from the upper surface of the edge having the closed structure of the fixation liquid storage compartment 121.

As shown in the drawing, the rotation and downward induction protrusions 124 may be disposed at four sides in the directions of the east, west, and north along the upper edge of the inner cylinder 120, as shown in FIG.

The bottom surface of the tissue specimen storing part 122 having the fixing fluid inflow hole 123 is formed to be positioned above the lower surface of the inner tube 120 and is fixed to the bottom surface of the outer tube 110 and the bottom surface of the inner tube 120 When the container lid 140 is threadedly coupled to the outer cylinder 110 by sealing the sealant 130 with the gap therebetween, when the sealant breakage protrusion 111 tears and breaks the sealant 130, (1) to the tissue sample storage part (122) without blocking the movement flow according to the flow and movement principle of the fluid, and to mix the tissue sample (1) with the tissue sample (1) So that it can be locked.

The sealing material 130 is attached to a lower surface of the fixing chamber 2 of the inner cylinder 120 in a state where the fixing solution 2 is introduced into the fixing solution storage compartment 121. The fixing solution 2 is inserted into the fixing solution storage compartment 121 As shown in FIG.

The sealing material 130 may be made of a soft material so as to be easily broken when the sealing material 130 is in contact with the sealing material breakage protrusion 111 of the outer tube 110, and may be one selected from aluminum foil, silver foil and vinyl paper.

The container lid 140 is a lid member that simultaneously covers the outer cylinder 110 and the inner cylinder 120 which are double-arranged as a cap-shaped body having an internal thread 141 for engaging with the outer cylinder 110. The outer cylinder 110 And presses the inner tube 120 to rotate and pulls the inner tube 120 at the same time.

At this time, the container lid 140 is formed with a rotating and descending pull projection 142 protruding from the inner edge of the cap body.

The rotation and descending traction protrusion 142 may be provided at one or more sides of the inner surface of the container lid 140 in contact with the rotation and descent induction protrusions 124 so as to be pullable. It can be radially arranged with equal spacing.

That is, when the container lid 140 is threadedly coupled to the outer cylinder 110, the rotary and descending pull protrusions 142 are positioned between the rotation and the downward protrusions 124, Respectively.

The use and operation of the tissue sample container 100 according to one embodiment of the present invention having the above-described structure will be described as follows.

The fixation liquid 2 is charged into the fixation liquid storage compartment 121 of the inner tube 120 and then stored therein so that the sealant 130 covers the lower surface of the fixation liquid storage compartment 121 or the inner tube 120 ) So as to cover the entire lower surface.

Then, the tissue sample 1 collected from the lesion site of the patient is stored in the tissue sample storage unit 122 of the inner tube 120 and stored.

In this state, the inner cylinder 110, in which the tissue specimen 1 and the fixing liquid 2 are separated and stored, is inserted into the outer cylinder 110.

At this time, the inner tube 120 is inserted into the initial outer tube 110 in such a manner that the inner tube 120 is inserted, and the sealing member breakage protrusions 111 and the sealing member 130 are initially disposed in a noncontact state.

The container lid 140 may be threadedly coupled to the outer cylinder 110 from the upper side while the inner cylinder 120 is initially disposed inside the outer cylinder 110. When the container lid 140 is screwed to the outer cylinder 110, The inner cylinder 120 is rotated and lowered in the outer cylinder 110 due to the rotation and the descending pull projection 142 of the container lid 140 pulling the rotation and lowering induction projection 124 on the inner cylinder 120 side, 120 are rotated and lowered, the sealing material 130 is forcibly brought into contact with the sealing breakage protrusion 111 side, so that external pressure is applied to the sealing material 130, which is torn and broken.

The fixing fluid 2 stored in the fixing fluid storage compartment 121 on the inner cylinder 120 side is discharged toward the bottom surface of the outer cylinder 110 as the sealing material 130 is broken and the fixing fluid 2 is discharged into the outer cylinder 110 The tissue specimens 1 and 2 stored in the tissue specimen storage part 122 are directly introduced into the tissue specimen storage part 122 through the fixation liquid inflow hole 123 located on the bottom surface of the inner tube 120, The fixing liquid 2 is mixed.

Thus, the tissue sample 1 is immersed and immobilized in the fixative 2, and is processed to be preserved.

After the container lid 140 is detached from the outer cylinder 110 and the inner cylinder 120 is taken out, the inspecting person holds the fixing liquid 2 in the outer cylinder 110 while leaving the tissue sample fixed by the fixing fluid The tissue sample (1) can be easily separated and the tissue sample separated from the fixer can be used for the examination.

One embodiment of the present invention is to provide a new structure and method for infiltrating and immobilizing the fixation fluid 2 into the tissue sample 1 through breakage of the sealing material 130 by applying a sealant 130, It is possible to provide an advantage of simplifying a work process of separating and using only a tissue specimen from the specimen container 100.

In particular, when the tissue sample container 100 is tilted or turned upside down while the fixation liquid 2 is fixed to the tissue sample 1, the tissue sample 1 and the fixation liquid 2 are not separated from each other, Function can be maintained and it is possible to provide an advantage that the tissue sample 1 and the fixing liquid 2 can always be mixed and maintained in a fixed state in the container regardless of the state of the tissue sample container 100 have.

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While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments, but, on the contrary, is intended to cover various modifications and equivalent arrangements included within the spirit and scope of the appended claims. The modifications will fall within the technical scope of this invention.

100: tissue sample container 110: outer tube
111: sealing material breakage protrusion 120: inner tube
121: fixer storage compartment 122: tissue specimen storage unit
123: fixing liquid inflow hole 124: rotation and descent guiding projection
130: sealing material 140: container lid
142: rotation and descending traction projection

Claims (5)

1. A tissue sample container for storing a tissue sample collected from a lesion site of a patient and storing a fixation solution as a liquid content for storage and long term storage through fixation of the tissue sample together with a tissue sample,
An outer tube having a bottom surface of the inner space protruding from a sealing material breakage protrusion and having an outer thread formed on an outer surface of an upper end thereof;
A lower liquid storage compartment is formed around the periphery of the seal body, a lower liquid storage compartment is formed around the periphery of the seal body, A plurality of fixing fluid inflow holes are formed on the bottom surface of the tissue sample storing part to allow the fixing fluid discharged from the fixing fluid storage compartment to flow in an external force;
A sealing member attached to the lower surface of the inner cylinder in a state where the fixing solution is introduced into the fixing solution storage compartment of the inner tube, the sealing member sealing the fixing solution storage compartment;
A cap body having an internal thread for engaging with the outer tube, the container lid being configured to press and push the inner tube during rotation due to thread engagement of the outer passage to rotate and pull down; / RTI >
When the container lid is threadedly coupled to the outer cylinder, the inner cylinder is pulled up and down, and the sealing material is torn and broken due to contact with the sealing material breakage protrusion of the outer cylinder. As a result, the fixed liquid stored in the fixed liquid storage compartment is discharged, And the tissue sample and the fixation solution stored therein are mixed with the fixation solution.
The method according to claim 1,
Wherein the inner cylinder is provided with a rotation and lowering protrusion protruding from the upper surface of the edge having the closed structure of the fixation liquid storage compartment,
Wherein the container lid is formed with a rotating and descending traction protrusion protruding from an inner peripheral edge thereof;
When the container lid is threadedly coupled to the outer cylinder, the container lid side rotating and lowering pulling projections pull the inner cylinder side rotating and lowering inducing projections to rotate and lower the inner tube, thereby forcibly contacting the sealing material to the sealing failure projection side to break the sealing material Wherein the tissue sample container is provided with a tissue sample container.
The method according to claim 1,
The bottom surface of the tissue specimen storage part having the fixer solution inflow hole is formed to be located above the lower surface of the inner tube so that the flow of the fixing solution is smoothly flowed into the tissue specimen storage part according to the flow and movement principle of the fluid, Features a tissue sample container.
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KR2020190000496U 2019-01-31 2019-01-31 Container for tissue samples KR200489217Y1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR2020190000496U KR200489217Y1 (en) 2019-01-31 2019-01-31 Container for tissue samples

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Application Number Priority Date Filing Date Title
KR2020190000496U KR200489217Y1 (en) 2019-01-31 2019-01-31 Container for tissue samples

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Publication Number Publication Date
KR200489217Y1 true KR200489217Y1 (en) 2019-05-17

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102597772B1 (en) 2023-07-28 2023-11-03 (주) 메디포유 Transport container for tissue samples

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101624962B1 (en) 2014-07-25 2016-05-27 (주)메디포유 Transport container for tissue samples
KR101798330B1 (en) * 2016-06-22 2017-12-12 이현구 Container for clinical specimen
KR101823438B1 (en) 2016-11-29 2018-01-30 (주)메디포유 Transport container for tissue samples
KR20180113078A (en) * 2017-04-05 2018-10-15 김종옥 Container for preserving tissue
KR20180113076A (en) * 2017-04-05 2018-10-15 삼성중공업 주식회사 Heavy weight supporting apparatus
KR101934819B1 (en) * 2018-05-24 2019-01-03 주식회사 골든바이오텍 Specimen container

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101624962B1 (en) 2014-07-25 2016-05-27 (주)메디포유 Transport container for tissue samples
KR101798330B1 (en) * 2016-06-22 2017-12-12 이현구 Container for clinical specimen
KR101823438B1 (en) 2016-11-29 2018-01-30 (주)메디포유 Transport container for tissue samples
KR20180113078A (en) * 2017-04-05 2018-10-15 김종옥 Container for preserving tissue
KR20180113076A (en) * 2017-04-05 2018-10-15 삼성중공업 주식회사 Heavy weight supporting apparatus
KR101934819B1 (en) * 2018-05-24 2019-01-03 주식회사 골든바이오텍 Specimen container

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102597772B1 (en) 2023-07-28 2023-11-03 (주) 메디포유 Transport container for tissue samples

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