KR20180038045A - B7-h3과 cd3에 결합할 수 있는 이중특이적 1가 디아바디, 및 그것의 사용 - Google Patents
B7-h3과 cd3에 결합할 수 있는 이중특이적 1가 디아바디, 및 그것의 사용 Download PDFInfo
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| CN112789294A (zh) | 2018-07-24 | 2021-05-11 | 印希比股份有限公司 | 含有受限cd3结合结构域和受体结合区的多特异性多肽构建体及其使用方法 |
| CN109762068A (zh) * | 2018-08-09 | 2019-05-17 | 源道隆（苏州）医学科技有限公司 | 一种可靶向ctla4和pd-1的单基因双特异性抗体及其应用 |
| US11208485B2 (en) | 2018-10-11 | 2021-12-28 | Inhibrx, Inc. | PD-1 single domain antibodies and therapeutic compositions thereof |
| WO2020076970A1 (en) | 2018-10-11 | 2020-04-16 | Inhibrx, Inc. | B7h3 single domain antibodies and therapeutic compositions thereof |
| TW202033218A (zh) * | 2018-12-07 | 2020-09-16 | 大陸商江蘇恆瑞醫藥股份有限公司 | 多特異性蛋白分子 |
| BR112021010026A2 (pt) | 2018-12-07 | 2021-08-17 | Jiangsu Hengrui Medicine Co., Ltd. | anticorpo cd3 e seu uso farmacêutico |
| KR102732027B1 (ko) * | 2019-07-09 | 2024-11-20 | 주식회사 와이바이오로직스 | B7-h3(cd276)에 특이적으로 결합하는 항체 및 그의 용도 |
| CN111454357B (zh) * | 2019-08-14 | 2022-03-15 | 康诺亚生物医药科技（成都）有限公司 | 一种含有抗体的肿瘤治疗剂的开发和应用 |
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| CN115380047A (zh) | 2020-01-29 | 2022-11-22 | 印希比股份有限公司 | Cd28单结构域抗体及其多价和多特异性构建体 |
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| CN113527493B (zh) * | 2021-07-20 | 2023-10-27 | 广州爱思迈生物医药科技有限公司 | 一种b7-h3抗体及其应用 |
| US20230151095A1 (en) | 2021-11-12 | 2023-05-18 | Xencor, Inc. | Bispecific antibodies that bind to b7h3 and nkg2d |
| CN114539420B (zh) * | 2022-01-20 | 2024-05-17 | 荣昌生物制药(烟台)股份有限公司 | 抗b7-h3单克隆抗体、抗b7-h3×cd3双特异性抗体、制备方法及其应用 |
| CN117903311B (zh) * | 2024-03-20 | 2024-10-25 | 湖南卓润生物科技有限公司 | sST2特异性结合蛋白及其制备方法和应用 |
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| ME03440B (me) * | 2011-05-21 | 2020-01-20 | Macrogenics Inc | Cd3-vezujući molekuli sposobni za vezivanje za humani i nehumani cd3 |
| US10851178B2 (en) * | 2011-10-10 | 2020-12-01 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
| US9487587B2 (en) * | 2013-03-05 | 2016-11-08 | Macrogenics, Inc. | Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof |
| US20140302037A1 (en) * | 2013-03-15 | 2014-10-09 | Amgen Inc. | BISPECIFIC-Fc MOLECULES |
| UA116479C2 (uk) * | 2013-08-09 | 2018-03-26 | Макродженікс, Інк. | БІСПЕЦИФІЧНЕ МОНОВАЛЕНТНЕ Fc-ДІАТІЛО, ЯКЕ ОДНОЧАСНО ЗВ'ЯЗУЄ CD32B I CD79b, ТА ЙОГО ЗАСТОСУВАННЯ |
| EP2839842A1 (en) * | 2013-08-23 | 2015-02-25 | MacroGenics, Inc. | Bi-specific monovalent diabodies that are capable of binding CD123 and CD3 and uses thereof |
| IL258521B2 (en) * | 2015-10-08 | 2024-01-01 | Macrogenics Inc | Combination therapy for the treatment of cancer |
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2016
- 2016-08-12 MA MA042665A patent/MA42665A/fr unknown
- 2016-08-12 HK HK18109035.8A patent/HK1249423A1/zh unknown
- 2016-08-12 WO PCT/US2016/046680 patent/WO2017030926A1/en not_active Ceased
- 2016-08-12 EA EA201890443A patent/EA201890443A1/ru unknown
- 2016-08-12 KR KR1020187007443A patent/KR20180038045A/ko not_active Withdrawn
- 2016-08-12 CR CR20180105A patent/CR20180105A/es unknown
- 2016-08-12 MX MX2018001954A patent/MX2018001954A/es unknown
- 2016-08-12 PE PE2018000249A patent/PE20181066A1/es unknown
- 2016-08-12 CN CN201680048182.7A patent/CN107921130A/zh active Pending
- 2016-08-12 EP EP16837560.8A patent/EP3337507A4/en not_active Withdrawn
- 2016-08-12 CA CA2995709A patent/CA2995709A1/en not_active Abandoned
- 2016-08-12 US US15/752,367 patent/US20190002563A1/en not_active Abandoned
- 2016-08-12 JP JP2018508741A patent/JP2018523686A/ja active Pending
- 2016-08-12 AU AU2016307955A patent/AU2016307955A1/en not_active Abandoned
- 2016-08-16 TW TW105126154A patent/TW201718652A/zh unknown
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2018
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- 2018-02-15 PH PH12018500363A patent/PH12018500363A1/en unknown
- 2018-02-15 CO CONC2018/0001485A patent/CO2018001485A2/es unknown
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- 2018-02-15 IL IL257562A patent/IL257562A/en unknown
- 2018-02-15 CL CL2018000422A patent/CL2018000422A1/es unknown
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| IL257562A (en) | 2018-04-30 |
| CO2018001485A2 (es) | 2018-07-10 |
| PH12018500363A1 (en) | 2018-09-10 |
| TW201718652A (zh) | 2017-06-01 |
| CN107921130A (zh) | 2018-04-17 |
| CR20180105A (es) | 2018-06-12 |
| EA201890443A1 (ru) | 2018-09-28 |
| HK1249423A1 (zh) | 2018-11-02 |
| ZA201800955B (en) | 2018-11-28 |
| CA2995709A1 (en) | 2017-02-23 |
| CL2018000422A1 (es) | 2018-08-10 |
| EP3337507A1 (en) | 2018-06-27 |
| ECSP18011248A (es) | 2018-04-30 |
| US20190002563A1 (en) | 2019-01-03 |
| EP3337507A4 (en) | 2019-04-24 |
| PE20181066A1 (es) | 2018-07-04 |
| WO2017030926A1 (en) | 2017-02-23 |
| AU2016307955A1 (en) | 2018-03-08 |
| MX2018001954A (es) | 2018-11-09 |
| MA42665A (fr) | 2018-06-27 |
| JP2018523686A (ja) | 2018-08-23 |
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