KR20180037948A - 병용 요법을 위한 vegfr-2 표적화 dna 백신 - Google Patents

병용 요법을 위한 vegfr-2 표적화 dna 백신 Download PDF

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KR20180037948A
KR20180037948A KR1020187001398A KR20187001398A KR20180037948A KR 20180037948 A KR20180037948 A KR 20180037948A KR 1020187001398 A KR1020187001398 A KR 1020187001398A KR 20187001398 A KR20187001398 A KR 20187001398A KR 20180037948 A KR20180037948 A KR 20180037948A
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하인즈 루베나우
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백심 아게
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001102Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103Receptors for growth factors
    • A61K39/001109Vascular endothelial growth factor receptors [VEGFR]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/0011Cancer antigens
    • A61K39/001152Transcription factors, e.g. SOX or c-MYC
    • A61K39/001153Wilms tumor 1 [WT1]
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    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00Antineoplastic agents
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    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
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    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • A61K2039/585Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Vascular Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
KR1020187001398A 2015-06-18 2016-06-16 병용 요법을 위한 vegfr-2 표적화 dna 백신 Ceased KR20180037948A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020257001040A KR20250024816A (ko) 2015-06-18 2016-06-16 병용 요법을 위한 vegfr-2 표적화 dna 백신

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15001803.4 2015-06-18
EP15001803 2015-06-18
PCT/EP2016/001004 WO2016202459A1 (en) 2015-06-18 2016-06-16 Vegfr-2 targeting dna vaccine for combination therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020257001040A Division KR20250024816A (ko) 2015-06-18 2016-06-16 병용 요법을 위한 vegfr-2 표적화 dna 백신

Publications (1)

Publication Number Publication Date
KR20180037948A true KR20180037948A (ko) 2018-04-13

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ID=53476620

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020187001398A Ceased KR20180037948A (ko) 2015-06-18 2016-06-16 병용 요법을 위한 vegfr-2 표적화 dna 백신
KR1020257001040A Pending KR20250024816A (ko) 2015-06-18 2016-06-16 병용 요법을 위한 vegfr-2 표적화 dna 백신

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020257001040A Pending KR20250024816A (ko) 2015-06-18 2016-06-16 병용 요법을 위한 vegfr-2 표적화 dna 백신

Country Status (19)

Country Link
US (2) US10905752B2 (cg-RX-API-DMAC7.html)
EP (2) EP3626262B1 (cg-RX-API-DMAC7.html)
JP (1) JP6947649B2 (cg-RX-API-DMAC7.html)
KR (2) KR20180037948A (cg-RX-API-DMAC7.html)
CN (1) CN107995868B (cg-RX-API-DMAC7.html)
AU (1) AU2016278588B2 (cg-RX-API-DMAC7.html)
BR (1) BR112017027378A2 (cg-RX-API-DMAC7.html)
CA (1) CA2989247C (cg-RX-API-DMAC7.html)
DK (1) DK3310379T3 (cg-RX-API-DMAC7.html)
ES (2) ES2760699T3 (cg-RX-API-DMAC7.html)
HU (1) HUE046631T2 (cg-RX-API-DMAC7.html)
IL (1) IL256076A (cg-RX-API-DMAC7.html)
LT (1) LT3310379T (cg-RX-API-DMAC7.html)
MX (1) MX2017016183A (cg-RX-API-DMAC7.html)
PL (2) PL3310379T3 (cg-RX-API-DMAC7.html)
RU (1) RU2018101722A (cg-RX-API-DMAC7.html)
SI (1) SI3310379T1 (cg-RX-API-DMAC7.html)
WO (1) WO2016202459A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201708439B (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2019112977A (ru) * 2016-11-04 2020-12-04 Факсимм Аг Днк-вакцина, нацеленная на wt1, для комбинированной терапии
CA3050833A1 (en) * 2017-02-17 2018-08-23 Vaximm Ag Novel vegfr-2 targeting immunotherapy approach
JP7247097B2 (ja) * 2017-03-17 2023-03-28 バクシム アクチェンゲゼルシャフト がん免疫療法のための新規pd-l1標的dnaワクチン
AU2019334131B2 (en) * 2018-09-05 2025-12-18 NEC Oncolmmunity AS Neoantigen targeting DNA vaccine for combination therapy
WO2021144254A1 (en) 2020-01-13 2021-07-22 Vaximm Ag Salmonella-based dna vaccines in combination with an antibiotic
EP3922255A1 (en) * 2020-06-10 2021-12-15 Prokarium Limited Cancer therapy

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094410B2 (en) 2002-03-02 2006-08-22 The Scripps Research Institute DNA vaccine against proliferating endothelial cells and methods of use thereof
NO337687B1 (no) 2011-07-08 2016-06-06 Norsk Elektro Optikk As Hyperspektralt kamera og metode for å ta opp hyperspektrale data
MX355134B (es) * 2011-12-22 2018-04-06 Vaximm Ag Metodo para producir cepas atenuadas de salmonella con alto rendimiento.
US9415098B2 (en) * 2012-07-05 2016-08-16 Vaximm Ag DNA vaccine for use in pancreatic cancer patients
EP2897620B1 (en) * 2012-09-21 2020-07-22 Intensity Therapeutics, Inc Method of treating cancer
MX385338B (es) * 2013-02-22 2025-03-18 CureVac SE Combinación de vacunación e inhibición de la trayectoria pd-1.
JP6416877B2 (ja) * 2013-04-25 2018-10-31 バクシム アクチェンゲゼルシャフト ウィルムス腫瘍遺伝子wt1を標的とする癌免疫療法用のサルモネラベースのベクター
JP6662787B2 (ja) * 2013-12-18 2020-03-11 バキシム ゲゼルシャフト ミット ベシュレンクテル ハフツング 癌免疫療法のための新規msln標的化dnaワクチン
CA3050833A1 (en) * 2017-02-17 2018-08-23 Vaximm Ag Novel vegfr-2 targeting immunotherapy approach
JP7247097B2 (ja) * 2017-03-17 2023-03-28 バクシム アクチェンゲゼルシャフト がん免疫療法のための新規pd-l1標的dnaワクチン

Also Published As

Publication number Publication date
CN107995868A (zh) 2018-05-04
ZA201708439B (en) 2021-05-26
US20210077605A1 (en) 2021-03-18
EP3626262B1 (en) 2024-10-23
EP3626262A1 (en) 2020-03-25
IL256076A (en) 2018-01-31
PL3310379T3 (pl) 2020-03-31
HUE046631T2 (hu) 2020-03-30
AU2016278588B2 (en) 2022-03-31
PL3626262T3 (pl) 2025-02-17
CA2989247A1 (en) 2016-12-22
ES2760699T3 (es) 2020-05-14
ES2994561T3 (en) 2025-01-27
HK1252435A1 (en) 2019-05-24
LT3310379T (lt) 2019-12-27
KR20250024816A (ko) 2025-02-19
RU2018101722A3 (cg-RX-API-DMAC7.html) 2019-12-10
RU2018101722A (ru) 2019-07-18
US20180250345A1 (en) 2018-09-06
WO2016202459A1 (en) 2016-12-22
US10905752B2 (en) 2021-02-02
EP3310379A1 (en) 2018-04-25
SI3310379T1 (sl) 2020-02-28
AU2016278588A1 (en) 2017-12-21
JP6947649B2 (ja) 2021-10-13
EP3626262C0 (en) 2024-10-23
JP2018517419A (ja) 2018-07-05
DK3310379T3 (da) 2019-12-16
EP3310379B1 (en) 2019-11-06
CN107995868B (zh) 2021-07-13
BR112017027378A2 (pt) 2018-08-28
MX2017016183A (es) 2018-06-19
CA2989247C (en) 2023-10-17

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