PL3310379T3 - Szczepionka dna wycelowana w vegfr-2 do terapii skojarzonej - Google Patents

Szczepionka dna wycelowana w vegfr-2 do terapii skojarzonej

Info

Publication number
PL3310379T3
PL3310379T3 PL16736381T PL16736381T PL3310379T3 PL 3310379 T3 PL3310379 T3 PL 3310379T3 PL 16736381 T PL16736381 T PL 16736381T PL 16736381 T PL16736381 T PL 16736381T PL 3310379 T3 PL3310379 T3 PL 3310379T3
Authority
PL
Poland
Prior art keywords
vegfr
combination therapy
dna vaccine
targeting dna
targeting
Prior art date
Application number
PL16736381T
Other languages
English (en)
Polish (pl)
Inventor
Heinz Lubenau
Original Assignee
Vaximm Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaximm Ag filed Critical Vaximm Ag
Publication of PL3310379T3 publication Critical patent/PL3310379T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001102Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103Receptors for growth factors
    • A61K39/001109Vascular endothelial growth factor receptors [VEGFR]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001152Transcription factors, e.g. SOX or c-MYC
    • A61K39/001153Wilms tumor 1 [WT1]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001166Adhesion molecules, e.g. NRCAM, EpCAM or cadherins
    • A61K39/001168Mesothelin [MSLN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/00118Cancer antigens from embryonic or fetal origin
    • A61K39/001182Carcinoembryonic antigen [CEA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0275Salmonella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/58Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
PL16736381T 2015-06-18 2016-06-16 Szczepionka dna wycelowana w vegfr-2 do terapii skojarzonej PL3310379T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15001803 2015-06-18
EP16736381.1A EP3310379B1 (en) 2015-06-18 2016-06-16 Vegfr-2 targeting dna vaccine for combination therapy
PCT/EP2016/001004 WO2016202459A1 (en) 2015-06-18 2016-06-16 Vegfr-2 targeting dna vaccine for combination therapy

Publications (1)

Publication Number Publication Date
PL3310379T3 true PL3310379T3 (pl) 2020-03-31

Family

ID=53476620

Family Applications (2)

Application Number Title Priority Date Filing Date
PL16736381T PL3310379T3 (pl) 2015-06-18 2016-06-16 Szczepionka dna wycelowana w vegfr-2 do terapii skojarzonej
PL19205420.3T PL3626262T3 (pl) 2015-06-18 2016-06-16 Szczepionka dna ukierunkowana na vegfr-2 do terapii skojarzonej

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL19205420.3T PL3626262T3 (pl) 2015-06-18 2016-06-16 Szczepionka dna ukierunkowana na vegfr-2 do terapii skojarzonej

Country Status (19)

Country Link
US (2) US10905752B2 (cg-RX-API-DMAC7.html)
EP (2) EP3310379B1 (cg-RX-API-DMAC7.html)
JP (1) JP6947649B2 (cg-RX-API-DMAC7.html)
KR (2) KR20250024816A (cg-RX-API-DMAC7.html)
CN (1) CN107995868B (cg-RX-API-DMAC7.html)
AU (1) AU2016278588B2 (cg-RX-API-DMAC7.html)
BR (1) BR112017027378A2 (cg-RX-API-DMAC7.html)
CA (1) CA2989247C (cg-RX-API-DMAC7.html)
DK (1) DK3310379T3 (cg-RX-API-DMAC7.html)
ES (2) ES2760699T3 (cg-RX-API-DMAC7.html)
HU (1) HUE046631T2 (cg-RX-API-DMAC7.html)
IL (1) IL256076A (cg-RX-API-DMAC7.html)
LT (1) LT3310379T (cg-RX-API-DMAC7.html)
MX (1) MX2017016183A (cg-RX-API-DMAC7.html)
PL (2) PL3310379T3 (cg-RX-API-DMAC7.html)
RU (1) RU2018101722A (cg-RX-API-DMAC7.html)
SI (1) SI3310379T1 (cg-RX-API-DMAC7.html)
WO (1) WO2016202459A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201708439B (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2019112977A (ru) * 2016-11-04 2020-12-04 Факсимм Аг Днк-вакцина, нацеленная на wt1, для комбинированной терапии
SG11201907391SA (en) * 2017-02-17 2019-09-27 Vaximm Ag Novel vegfr-2 targeting immunotherapy approach
US11357842B2 (en) 2017-03-17 2022-06-14 Vaximm Ag PD-L1 targeting DNA vaccine for cancer immunotherapy
CA3109430A1 (en) * 2018-09-05 2020-03-12 Vaximm Ag Neoantigen targeting dna vaccine for combination therapy
AU2021208400A1 (en) * 2020-01-13 2022-08-11 Vaximm Ag Salmonella-based DNA vaccines in combination with an antibiotic
EP3922255A1 (en) * 2020-06-10 2021-12-15 Prokarium Limited Cancer therapy

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094410B2 (en) 2002-03-02 2006-08-22 The Scripps Research Institute DNA vaccine against proliferating endothelial cells and methods of use thereof
NO337687B1 (no) 2011-07-08 2016-06-06 Norsk Elektro Optikk As Hyperspektralt kamera og metode for å ta opp hyperspektrale data
BR112014015706A2 (pt) * 2011-12-22 2020-10-27 Vaximm Ag método para o cultivo de uma estirpe mutante atenuada de salmonella typhi, estirpe mutante atenuada de salmonella typhi e salmonella typhi ty21a
BR112014033046A2 (pt) * 2012-07-05 2017-06-27 Vaximm Ag linhagem mutante atenuada de salmonella typhi, vacina de dna e vacina de dna vxm01
PT2897620T (pt) * 2012-09-21 2020-09-03 Intensity Therapeutics Inc Método de tratamento de cancro
SG10201710472PA (en) * 2013-02-22 2018-02-27 Curevac Ag Combination of vaccination and inhibition of the pd-1 pathway
CN105246496A (zh) * 2013-04-25 2016-01-13 万科斯蒙股份有限公司 用于癌症免疫治疗的靶向肾母细胞瘤基因wt-1的基于沙门菌的载体
BR112016014405A2 (pt) * 2013-12-18 2018-02-20 Vaximm Gmbh cepa mutante atenuada de salmonela
SG11201907391SA (en) * 2017-02-17 2019-09-27 Vaximm Ag Novel vegfr-2 targeting immunotherapy approach
US11357842B2 (en) * 2017-03-17 2022-06-14 Vaximm Ag PD-L1 targeting DNA vaccine for cancer immunotherapy

Also Published As

Publication number Publication date
KR20180037948A (ko) 2018-04-13
EP3310379A1 (en) 2018-04-25
RU2018101722A (ru) 2019-07-18
EP3626262A1 (en) 2020-03-25
CN107995868A (zh) 2018-05-04
MX2017016183A (es) 2018-06-19
RU2018101722A3 (cg-RX-API-DMAC7.html) 2019-12-10
DK3310379T3 (da) 2019-12-16
CA2989247A1 (en) 2016-12-22
ES2760699T3 (es) 2020-05-14
LT3310379T (lt) 2019-12-27
EP3626262B1 (en) 2024-10-23
US20180250345A1 (en) 2018-09-06
AU2016278588A1 (en) 2017-12-21
EP3310379B1 (en) 2019-11-06
HUE046631T2 (hu) 2020-03-30
BR112017027378A2 (pt) 2018-08-28
CA2989247C (en) 2023-10-17
SI3310379T1 (sl) 2020-02-28
ES2994561T3 (en) 2025-01-27
ZA201708439B (en) 2021-05-26
EP3626262C0 (en) 2024-10-23
AU2016278588B2 (en) 2022-03-31
IL256076A (en) 2018-01-31
WO2016202459A1 (en) 2016-12-22
PL3626262T3 (pl) 2025-02-17
US10905752B2 (en) 2021-02-02
JP6947649B2 (ja) 2021-10-13
US20210077605A1 (en) 2021-03-18
HK1252435A1 (en) 2019-05-24
JP2018517419A (ja) 2018-07-05
KR20250024816A (ko) 2025-02-19
CN107995868B (zh) 2021-07-13

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