KR20180034442A - 아캄프로세이트와 d-사이클로세린을 사용한 병용 치료 - Google Patents

아캄프로세이트와 d-사이클로세린을 사용한 병용 치료 Download PDF

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Publication number
KR20180034442A
KR20180034442A KR1020187002542A KR20187002542A KR20180034442A KR 20180034442 A KR20180034442 A KR 20180034442A KR 1020187002542 A KR1020187002542 A KR 1020187002542A KR 20187002542 A KR20187002542 A KR 20187002542A KR 20180034442 A KR20180034442 A KR 20180034442A
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KR
South Korea
Prior art keywords
cycloserine
administered
therapeutic agent
patient
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020187002542A
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English (en)
Korean (ko)
Inventor
스티븐 엘. 존스
크레이그 에이. 에릭슨
Original Assignee
컨플루언스 파마슈티컬스, 엘엘씨
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Application filed by 컨플루언스 파마슈티컬스, 엘엘씨 filed Critical 컨플루언스 파마슈티컬스, 엘엘씨
Publication of KR20180034442A publication Critical patent/KR20180034442A/ko
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR1020187002542A 2015-08-04 2016-08-04 아캄프로세이트와 d-사이클로세린을 사용한 병용 치료 Ceased KR20180034442A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562200864P 2015-08-04 2015-08-04
US62/200,864 2015-08-04
PCT/US2016/045547 WO2017024129A1 (en) 2015-08-04 2016-08-04 Combination therapy using acamprosate and d-cycloserine

Publications (1)

Publication Number Publication Date
KR20180034442A true KR20180034442A (ko) 2018-04-04

Family

ID=57944041

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020187002542A Ceased KR20180034442A (ko) 2015-08-04 2016-08-04 아캄프로세이트와 d-사이클로세린을 사용한 병용 치료

Country Status (11)

Country Link
US (2) US20180221315A1 (https=)
EP (1) EP3331518A4 (https=)
JP (2) JP2018526345A (https=)
KR (1) KR20180034442A (https=)
AU (2) AU2016303610A1 (https=)
CA (1) CA2993614A1 (https=)
HK (1) HK1255584A1 (https=)
IL (1) IL257035A (https=)
SG (1) SG10201914045QA (https=)
WO (1) WO2017024129A1 (https=)
ZA (1) ZA201800558B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017024129A1 (en) * 2015-08-04 2017-02-09 Confluence Pharmaceuticals, Llc Combination therapy using acamprosate and d-cycloserine
IL270654B2 (en) 2017-05-17 2024-07-01 Confluence Pharmaceuticals Llc Formulations of homotaurines and salts thereof
CA3064846A1 (en) 2017-05-25 2018-11-29 Glytech, Llc Combined therapy for nmdar antagonist-responsive neuropsychiatric disorders
US11291654B2 (en) * 2018-09-13 2022-04-05 Syneurx International (Taiwan) Corp. Formulations of cycloserine compounds and applications thereof
JP2025069475A (ja) * 2022-03-08 2025-05-01 ソシウム株式会社 Tdp-43の凝集の抑制剤、tdp-43が過剰発現している細胞の細胞死の抑制剤、及びtdp-43の凝集を伴う疾患の治療又は予防剤
EP4702978A1 (en) * 2023-04-27 2026-03-04 Socium Inc. Agent for treating or preventing amyotrophic lateral sclerosis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1073432B1 (en) * 1998-04-14 2007-08-15 The General Hospital Corporation Use of d-serine or d-alanine for treating schizophrenia
US20100216734A1 (en) * 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
JP2010532331A (ja) * 2007-07-05 2010-10-07 アンセルム(アンスチチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル) 抗痙攣医薬組成物
HRP20150120T1 (hr) * 2009-02-12 2015-05-08 Indiana University Research And Technology Corporation Materijal i metode za lijeäśenje poremeä†aja u razvoju ukljuäśujuä†i komorbidni i idiopatski autizam
WO2010099217A1 (en) * 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
JP5893135B2 (ja) * 2011-06-28 2016-03-23 ビボゾーン インコーポレイテッド 多重ターゲッティングの相乗効果を誘発する有効物質の組合せ及びその用途
KR102790656B1 (ko) * 2015-05-04 2025-04-02 컨플루언스 파마슈티컬스, 엘엘씨 아캄프로세이트의 스프링클 제형
WO2017024129A1 (en) * 2015-08-04 2017-02-09 Confluence Pharmaceuticals, Llc Combination therapy using acamprosate and d-cycloserine

Also Published As

Publication number Publication date
US20180221315A1 (en) 2018-08-09
SG10201914045QA (en) 2020-03-30
EP3331518A4 (en) 2019-04-03
EP3331518A1 (en) 2018-06-13
AU2022202218A1 (en) 2022-04-21
JP2018526345A (ja) 2018-09-13
JP2021152060A (ja) 2021-09-30
WO2017024129A1 (en) 2017-02-09
IL257035A (en) 2018-03-29
AU2016303610A1 (en) 2018-02-01
CA2993614A1 (en) 2017-02-09
HK1255584A1 (zh) 2019-08-23
ZA201800558B (en) 2019-10-30
US20200360316A1 (en) 2020-11-19

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