HK1255584A1 - 使用阿坎酸及d-环丝胺酸的联合疗法 - Google Patents

使用阿坎酸及d-环丝胺酸的联合疗法 Download PDF

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Publication number
HK1255584A1
HK1255584A1 HK18114711.9A HK18114711A HK1255584A1 HK 1255584 A1 HK1255584 A1 HK 1255584A1 HK 18114711 A HK18114711 A HK 18114711A HK 1255584 A1 HK1255584 A1 HK 1255584A1
Authority
HK
Hong Kong
Prior art keywords
cycloserine
acamprosate
combination therapy
patient
therapeutic agent
Prior art date
Application number
HK18114711.9A
Other languages
English (en)
Chinese (zh)
Inventor
Steven L. JOHNS
Craig A. ERICKSON
Original Assignee
Confluence Pharmaceuticals, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Confluence Pharmaceuticals, Llc filed Critical Confluence Pharmaceuticals, Llc
Publication of HK1255584A1 publication Critical patent/HK1255584A1/zh

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
HK18114711.9A 2015-08-04 2016-08-04 使用阿坎酸及d-环丝胺酸的联合疗法 HK1255584A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562200864P 2015-08-04 2015-08-04
US62/200,864 2015-08-04
PCT/US2016/045547 WO2017024129A1 (en) 2015-08-04 2016-08-04 Combination therapy using acamprosate and d-cycloserine

Publications (1)

Publication Number Publication Date
HK1255584A1 true HK1255584A1 (zh) 2019-08-23

Family

ID=57944041

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18114711.9A HK1255584A1 (zh) 2015-08-04 2016-08-04 使用阿坎酸及d-环丝胺酸的联合疗法

Country Status (11)

Country Link
US (2) US20180221315A1 (https=)
EP (1) EP3331518A4 (https=)
JP (2) JP2018526345A (https=)
KR (1) KR20180034442A (https=)
AU (2) AU2016303610A1 (https=)
CA (1) CA2993614A1 (https=)
HK (1) HK1255584A1 (https=)
IL (1) IL257035A (https=)
SG (1) SG10201914045QA (https=)
WO (1) WO2017024129A1 (https=)
ZA (1) ZA201800558B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1255584A1 (zh) * 2015-08-04 2019-08-23 Confluence Pharmaceuticals, Llc 使用阿坎酸及d-环丝胺酸的联合疗法
IL270654B2 (en) 2017-05-17 2024-07-01 Confluence Pharmaceuticals Llc Formulations of homotaurines and salts thereof
RU2019143572A (ru) 2017-05-25 2021-06-25 Глитек Ллс. Композиции для лечения посттравматического стрессового расстройства
US11291654B2 (en) * 2018-09-13 2022-04-05 Syneurx International (Taiwan) Corp. Formulations of cycloserine compounds and applications thereof
JP2025069475A (ja) * 2022-03-08 2025-05-01 ソシウム株式会社 Tdp-43の凝集の抑制剤、tdp-43が過剰発現している細胞の細胞死の抑制剤、及びtdp-43の凝集を伴う疾患の治療又は予防剤
WO2024224537A1 (ja) * 2023-04-27 2024-10-31 ソシウム株式会社 筋萎縮性側索硬化症の治療又は予防剤

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1073432T1 (de) * 1998-04-14 2002-02-07 The General Hospital Corp., Boston Verwendung von glycinrezeptoragonisten und glycinaufnahmeinhibitoren zur behandlung neuropsychiatrischer beschwerden
US20100216734A1 (en) * 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
JP2010532331A (ja) * 2007-07-05 2010-10-07 アンセルム(アンスチチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル) 抗痙攣医薬組成物
CA2781830C (en) * 2009-02-12 2018-03-27 Indiana University Research & Technology Corporation Materials and methods for treating developmental disorders including comorbid and idiopathic autism
WO2010099217A1 (en) * 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
JP5893135B2 (ja) * 2011-06-28 2016-03-23 ビボゾーン インコーポレイテッド 多重ターゲッティングの相乗効果を誘発する有効物質の組合せ及びその用途
SG11201708393UA (en) * 2015-05-04 2017-11-29 Confluence Pharmaceuticals Llc Sprinkle formulations of acamprosate
HK1255584A1 (zh) * 2015-08-04 2019-08-23 Confluence Pharmaceuticals, Llc 使用阿坎酸及d-环丝胺酸的联合疗法

Also Published As

Publication number Publication date
EP3331518A4 (en) 2019-04-03
EP3331518A1 (en) 2018-06-13
SG10201914045QA (en) 2020-03-30
AU2022202218A1 (en) 2022-04-21
US20200360316A1 (en) 2020-11-19
JP2018526345A (ja) 2018-09-13
AU2016303610A1 (en) 2018-02-01
US20180221315A1 (en) 2018-08-09
KR20180034442A (ko) 2018-04-04
JP2021152060A (ja) 2021-09-30
IL257035A (en) 2018-03-29
CA2993614A1 (en) 2017-02-09
ZA201800558B (en) 2019-10-30
WO2017024129A1 (en) 2017-02-09

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