KR20180003545A - 질환의 치료를 위한 융합된 비시클릭 화합물 - Google Patents
질환의 치료를 위한 융합된 비시클릭 화합물 Download PDFInfo
- Publication number
- KR20180003545A KR20180003545A KR1020177030777A KR20177030777A KR20180003545A KR 20180003545 A KR20180003545 A KR 20180003545A KR 1020177030777 A KR1020177030777 A KR 1020177030777A KR 20177030777 A KR20177030777 A KR 20177030777A KR 20180003545 A KR20180003545 A KR 20180003545A
- Authority
- KR
- South Korea
- Prior art keywords
- optionally substituted
- alkyl
- formula
- compound
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 0 C*1(C)CCOCC1 Chemical compound C*1(C)CCOCC1 0.000 description 75
- ZPPMAROSXRPSBG-UHFFFAOYSA-N C[N]1(CC2)CCN2CC1 Chemical compound C[N]1(CC2)CCN2CC1 ZPPMAROSXRPSBG-UHFFFAOYSA-N 0.000 description 8
- AJKAVLDLBYUQRM-FPLPWBNLSA-N CC(C)(C)CNN(C)/C=C\C=C Chemical compound CC(C)(C)CNN(C)/C=C\C=C AJKAVLDLBYUQRM-FPLPWBNLSA-N 0.000 description 1
- HBLFRHVRUPNRGV-UHFFFAOYSA-N CC(C)(CN)c1c[nH]c2ncccc12 Chemical compound CC(C)(CN)c1c[nH]c2ncccc12 HBLFRHVRUPNRGV-UHFFFAOYSA-N 0.000 description 1
- HHYVSGVMRCNYIL-UHFFFAOYSA-N CC(C)(CN=C)c1c[nH]c2ncccc12 Chemical compound CC(C)(CN=C)c1c[nH]c2ncccc12 HHYVSGVMRCNYIL-UHFFFAOYSA-N 0.000 description 1
- MBTUZNKTKYBZQY-UHFFFAOYSA-N CC(C)OC(C(CBr)=O)=O Chemical compound CC(C)OC(C(CBr)=O)=O MBTUZNKTKYBZQY-UHFFFAOYSA-N 0.000 description 1
- NCUVNDOWABALOG-UHFFFAOYSA-N CC(C)OC(C(c1c(C(C)(C)C2)c(C)c(C#N)[nH]1)=CN2C(c(cc1)cc(F)c1F)=O)=O Chemical compound CC(C)OC(C(c1c(C(C)(C)C2)c(C)c(C#N)[nH]1)=CN2C(c(cc1)cc(F)c1F)=O)=O NCUVNDOWABALOG-UHFFFAOYSA-N 0.000 description 1
- MCGKCBPYGFFKNI-UHFFFAOYSA-N CC(C)OC(C(c1c(C(C)(C)C2)c(ccc(F)c3)c3[nH]1)=CN2C(N(CC1)CC[N]1(C)I)=O)=O Chemical compound CC(C)OC(C(c1c(C(C)(C)C2)c(ccc(F)c3)c3[nH]1)=CN2C(N(CC1)CC[N]1(C)I)=O)=O MCGKCBPYGFFKNI-UHFFFAOYSA-N 0.000 description 1
- XHVICXZLJPEPTP-UHFFFAOYSA-N CC(C)OC(C(c1c(C(C)(C)C2)c(ccc(F)c3)c3[nH]1)=CN2C(c(cc1)ccc1OCCC[N]1(C)CCOCC1)=O)=O Chemical compound CC(C)OC(C(c1c(C(C)(C)C2)c(ccc(F)c3)c3[nH]1)=CN2C(c(cc1)ccc1OCCC[N]1(C)CCOCC1)=O)=O XHVICXZLJPEPTP-UHFFFAOYSA-N 0.000 description 1
- DECQEFTYTAFMHZ-UHFFFAOYSA-O CC(C)OC(C(c1c(C(C)(C)C2)c(ccc(OC(NCc3[n+](C)cccc3)=O)c3)c3[nH]1)=CN2C(c(cc1)cc(F)c1F)=O)O Chemical compound CC(C)OC(C(c1c(C(C)(C)C2)c(ccc(OC(NCc3[n+](C)cccc3)=O)c3)c3[nH]1)=CN2C(c(cc1)cc(F)c1F)=O)O DECQEFTYTAFMHZ-UHFFFAOYSA-O 0.000 description 1
- KXZWOZBAPNRNNP-UHFFFAOYSA-N CC(C)OC(C(c1c(C(C)(C)C2)c(cccc3)c3[nH]1)=CN2C(c(cc1)ccc1OCCC[N+]1(C)CCOCC1)=O)=O Chemical compound CC(C)OC(C(c1c(C(C)(C)C2)c(cccc3)c3[nH]1)=CN2C(c(cc1)ccc1OCCC[N+]1(C)CCOCC1)=O)=O KXZWOZBAPNRNNP-UHFFFAOYSA-N 0.000 description 1
- BNNBRAKOFFJMAM-UHFFFAOYSA-N CC(C)OC(C(c1c(C(C)(C)C2)cc(C#N)[nH]1)=CN2C(c(cc1)cc(F)c1F)=O)=O Chemical compound CC(C)OC(C(c1c(C(C)(C)C2)cc(C#N)[nH]1)=CN2C(c(cc1)cc(F)c1F)=O)=O BNNBRAKOFFJMAM-UHFFFAOYSA-N 0.000 description 1
- BWJCKUYSZPZGQD-UHFFFAOYSA-N CC(C)OC(C(c1c(C(C)(C)C2)cn[nH]1)=CN2C(N(CC1)CC[N]1(C)I)=O)=O Chemical compound CC(C)OC(C(c1c(C(C)(C)C2)cn[nH]1)=CN2C(N(CC1)CC[N]1(C)I)=O)=O BWJCKUYSZPZGQD-UHFFFAOYSA-N 0.000 description 1
- IEPUPMVQKNWWPP-UHFFFAOYSA-N CC(C)OC(C(c1c(C(C)(C)C2)cn[nH]1)=CN2C(N1CCN(C)CCC1)=O)=O Chemical compound CC(C)OC(C(c1c(C(C)(C)C2)cn[nH]1)=CN2C(N1CCN(C)CCC1)=O)=O IEPUPMVQKNWWPP-UHFFFAOYSA-N 0.000 description 1
- ICWAIZDYGPIXSR-UHFFFAOYSA-N CC[N](C)(CC1)CCN1C(N(CC1(C)C)C=C(C(OC(C)C)=O)c([nH]2)c1c1c2nccc1)=O Chemical compound CC[N](C)(CC1)CCN1C(N(CC1(C)C)C=C(C(OC(C)C)=O)c([nH]2)c1c1c2nccc1)=O ICWAIZDYGPIXSR-UHFFFAOYSA-N 0.000 description 1
- PVOAHINGSUIXLS-UHFFFAOYSA-N CN1CCNCC1 Chemical compound CN1CCNCC1 PVOAHINGSUIXLS-UHFFFAOYSA-N 0.000 description 1
- CDPXZBQYOYANIZ-UHFFFAOYSA-N CN[NH+](C)[N-](C)C Chemical compound CN[NH+](C)[N-](C)C CDPXZBQYOYANIZ-UHFFFAOYSA-N 0.000 description 1
- XJTQJERLRPWUGL-UHFFFAOYSA-N ICc1ccccc1 Chemical compound ICc1ccccc1 XJTQJERLRPWUGL-UHFFFAOYSA-N 0.000 description 1
- KSBVCBLNHLSKFN-UHFFFAOYSA-N N#CCc1c[nH]c2ncccc12 Chemical compound N#CCc1c[nH]c2ncccc12 KSBVCBLNHLSKFN-UHFFFAOYSA-N 0.000 description 1
- SIKJAQJRHWYJAI-UHFFFAOYSA-N c1c[nH]c2ccccc12 Chemical compound c1c[nH]c2ccccc12 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 description 1
- MVXVYAKCVDQRLW-UHFFFAOYSA-N c1c[nH]c2ncccc12 Chemical compound c1c[nH]c2ncccc12 MVXVYAKCVDQRLW-UHFFFAOYSA-N 0.000 description 1
- FCEHBMOGCRZNNI-UHFFFAOYSA-N c1c[s]c2ccccc12 Chemical compound c1c[s]c2ccccc12 FCEHBMOGCRZNNI-UHFFFAOYSA-N 0.000 description 1
- HYZJCKYKOHLVJF-UHFFFAOYSA-N c1nc2ccccc2[nH]1 Chemical compound c1nc2ccccc2[nH]1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 description 1
- FYADHXFMURLYQI-UHFFFAOYSA-N c1ncnnc1 Chemical compound c1ncnnc1 FYADHXFMURLYQI-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562138725P | 2015-03-26 | 2015-03-26 | |
| US62/138,725 | 2015-03-26 | ||
| PCT/IB2016/000606 WO2016151403A1 (en) | 2015-03-26 | 2016-03-25 | Fused bicyclic compounds for the treatment of disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20180003545A true KR20180003545A (ko) | 2018-01-09 |
Family
ID=56072361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020177030777A Ceased KR20180003545A (ko) | 2015-03-26 | 2016-03-25 | 질환의 치료를 위한 융합된 비시클릭 화합물 |
Country Status (16)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2021107054A (ru) * | 2015-03-26 | 2021-03-31 | Акарна Терапьютикс, Лтд. | Конденсированные бициклические соединения для лечения заболевания |
| JP2019520335A (ja) * | 2016-05-25 | 2019-07-18 | アカーナ・セラピューティクス・リミテッドＡｋａｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｌｔｄ． | 疾患治療用の縮合二環式化合物 |
| MX2018014024A (es) * | 2016-05-25 | 2019-08-29 | Akarna Therapeutics Ltd | Terapias de combinación con moduladores del receptor x farnesoide (fxr). |
| BR112019025228A2 (pt) * | 2017-06-02 | 2020-06-23 | Akarna Therapeutics, Ltd. | Compostos bicíclicos fundidos |
| CN108264474B (zh) * | 2018-02-09 | 2019-10-25 | 浙江师范大学 | 一种色胺及其衍生物的合成方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI329111B (en) * | 2002-05-24 | 2010-08-21 | X Ceptor Therapeutics Inc | Azepinoindole and pyridoindole derivatives as pharmaceutical agents |
| US7595311B2 (en) * | 2002-05-24 | 2009-09-29 | Exelixis, Inc. | Azepinoindole derivatives as pharmaceutical agents |
| WO2005009387A2 (en) * | 2003-07-23 | 2005-02-03 | X-Ceptor Therapeutics Inc. | Azepine derivatives as pharmaceutical agents |
| EP1776112A4 (en) | 2004-08-10 | 2009-11-25 | Exelixis Inc | HETEROCYCLIC COMPOUNDS AS PHARMACEUTICAL AGENTS |
| WO2006109633A1 (ja) | 2005-04-07 | 2006-10-19 | Daiichi Sankyo Company, Limited | 置換インドール化合物 |
| WO2007070796A1 (en) * | 2005-12-15 | 2007-06-21 | Exelixis, Inc. | Azepinoindole derivatives as pharmaceutical agents |
| EP2121621B1 (en) | 2006-12-08 | 2014-05-07 | Exelixis Patent Company LLC | Lxr and fxr modulators |
| US20090131409A1 (en) * | 2007-10-22 | 2009-05-21 | Wyeth | 1,4,5,6,7,8-HEXAHYDRO -PYRROLO[2,3-d]AZEPINES AND -IMIDAZO[4,5-d]AZEPINES AS MODULATORS OF NUCLEAR RECEPTOR ACTIVITY |
| US20090137554A1 (en) | 2007-10-22 | 2009-05-28 | Wyeth | 1,4,5,6-TETRAHYDRO -PYRROLO[2,3-d]AZEPINES AND -IMIDAZO[4,5-d]AZEPINES AS MODULATORS OF NUCLEAR RECEPTOR ACTIVITY |
| JP2012503654A (ja) * | 2008-09-26 | 2012-02-09 | ワイス・エルエルシー | １，２，３，６−テトラヒドロアゼピノ［４，５−ｂ］インドール−５−カルボキシレート核内受容体阻害剤 |
| CA2968434A1 (en) * | 2014-11-21 | 2016-05-26 | Akarna Therapeutics, Ltd. | Fused bicyclic compounds for the treatment of disease |
| RU2741387C2 (ru) * | 2014-12-22 | 2021-01-25 | Акарна Терапьютикс, Лтд. | Конденсированные бициклические соединения для лечения заболевания |
| RU2021107054A (ru) * | 2015-03-26 | 2021-03-31 | Акарна Терапьютикс, Лтд. | Конденсированные бициклические соединения для лечения заболевания |
-
2016
- 2016-03-25 RU RU2021107054A patent/RU2021107054A/ru unknown
- 2016-03-25 EP EP20158977.7A patent/EP3715348A1/en not_active Withdrawn
- 2016-03-25 HK HK18109050.8A patent/HK1249756A1/zh unknown
- 2016-03-25 WO PCT/IB2016/000606 patent/WO2016151403A1/en not_active Ceased
- 2016-03-25 CA CA2980394A patent/CA2980394A1/en not_active Abandoned
- 2016-03-25 RU RU2017137366A patent/RU2017137366A/ru unknown
- 2016-03-25 SG SG10201908881P patent/SG10201908881PA/en unknown
- 2016-03-25 KR KR1020177030777A patent/KR20180003545A/ko not_active Ceased
- 2016-03-25 BR BR112017020374A patent/BR112017020374A2/pt not_active IP Right Cessation
- 2016-03-25 AU AU2016238523A patent/AU2016238523A1/en not_active Abandoned
- 2016-03-25 MX MX2017012342A patent/MX370897B/es active IP Right Grant
- 2016-03-25 SG SG11201707610PA patent/SG11201707610PA/en unknown
- 2016-03-25 JP JP2017550113A patent/JP6843061B2/ja not_active Expired - Fee Related
- 2016-03-25 CN CN201680029952.3A patent/CN107912042A/zh active Pending
- 2016-03-25 EP EP16724699.0A patent/EP3274350A1/en not_active Withdrawn
-
2017
- 2017-09-18 IL IL254572A patent/IL254572A0/en unknown
- 2017-09-25 US US15/714,013 patent/US10421759B2/en active Active
- 2017-09-25 CL CL2017002405A patent/CL2017002405A1/es unknown
- 2017-10-18 CO CONC2017/0010621A patent/CO2017010621A2/es unknown
-
2019
- 2019-09-19 US US16/575,965 patent/US20200079782A1/en not_active Abandoned
-
2020
- 2020-10-12 AU AU2020256301A patent/AU2020256301A1/en not_active Abandoned
- 2020-11-17 US US17/099,864 patent/US20210214362A1/en not_active Abandoned
-
2022
- 2022-04-19 US US17/724,138 patent/US20230002394A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016151403A1 (en) | 2016-09-29 |
| MX370897B (es) | 2020-01-09 |
| JP2018510876A (ja) | 2018-04-19 |
| US20180118752A1 (en) | 2018-05-03 |
| EP3274350A1 (en) | 2018-01-31 |
| CL2017002405A1 (es) | 2018-04-27 |
| HK1249756A1 (zh) | 2018-11-09 |
| CA2980394A1 (en) | 2016-09-29 |
| SG11201707610PA (en) | 2017-10-30 |
| US10421759B2 (en) | 2019-09-24 |
| IL254572A0 (en) | 2017-11-30 |
| AU2020256301A1 (en) | 2020-11-05 |
| US20230002394A1 (en) | 2023-01-05 |
| CO2017010621A2 (es) | 2018-01-31 |
| RU2017137366A3 (cg-RX-API-DMAC10.html) | 2019-07-17 |
| RU2021107054A (ru) | 2021-03-31 |
| CN107912042A (zh) | 2018-04-13 |
| EP3715348A1 (en) | 2020-09-30 |
| MX2017012342A (es) | 2018-06-11 |
| RU2017137366A (ru) | 2019-04-26 |
| US20210214362A1 (en) | 2021-07-15 |
| JP6843061B2 (ja) | 2021-03-17 |
| SG10201908881PA (en) | 2019-11-28 |
| AU2016238523A1 (en) | 2017-11-09 |
| BR112017020374A2 (pt) | 2018-06-05 |
| US20200079782A1 (en) | 2020-03-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20250171446A1 (en) | Fused bicyclic compounds for the treatment of disease | |
| US10793577B2 (en) | Fused bicyclic compounds for the treatment of disease | |
| US20210214362A1 (en) | Fused bicyclic compounds for the treatment of disease | |
| KR20190040140A (ko) | 질환의 치료를 위한 융합된 비시클릭 화합물 | |
| HK40049146A (en) | Fused bicyclic compounds for the treatment of disease | |
| HK1245795B (en) | Fused bicyclic compounds for the treatment of disease | |
| HK1244802B (en) | Fused bicyclic compounds for the treatment of disease |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20171025 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20210325 Comment text: Request for Examination of Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20230404 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20230717 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20230404 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |