KR20170058921A - 신규의 5,6-디하이드로-4H-벤조[b]티에노-[2,3-d]아제핀 유도체 - Google Patents

신규의 5,6-디하이드로-4H-벤조[b]티에노-[2,3-d]아제핀 유도체 Download PDF

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KR20170058921A
KR20170058921A KR1020177006394A KR20177006394A KR20170058921A KR 20170058921 A KR20170058921 A KR 20170058921A KR 1020177006394 A KR1020177006394 A KR 1020177006394A KR 20177006394 A KR20177006394 A KR 20177006394A KR 20170058921 A KR20170058921 A KR 20170058921A
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compound
rsv
formula
infection
compounds
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시몬 프레이저 헌트
스튜어트 토마스 어니언스
블라디미르 쉐르부킨
유안 알렉산더 프레이저 포다이스
피터 존 머레이
다니엘 윌리엄 브룩스
카즈히로 이토
피터 스트롱
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풀모사이드 리미티드
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    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
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    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020177006394A 2014-10-10 2015-10-08 신규의 5,6-디하이드로-4H-벤조[b]티에노-[2,3-d]아제핀 유도체 Withdrawn KR20170058921A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14188494 2014-10-10
EP14188494.0 2014-10-10
PCT/GB2015/052944 WO2016055791A1 (en) 2014-10-10 2015-10-08 Novel 5,6-dihydro-4H-benzo[b]thieno-[2,3-d]azepine derivative

Publications (1)

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KR20170058921A true KR20170058921A (ko) 2017-05-29

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KR1020177006394A Withdrawn KR20170058921A (ko) 2014-10-10 2015-10-08 신규의 5,6-디하이드로-4H-벤조[b]티에노-[2,3-d]아제핀 유도체

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US (6) US9732098B2 (enrdf_load_html_response)
EP (2) EP3204388B1 (enrdf_load_html_response)
JP (2) JP2017531039A (enrdf_load_html_response)
KR (1) KR20170058921A (enrdf_load_html_response)
CN (1) CN106852144B (enrdf_load_html_response)
AU (1) AU2015329789B2 (enrdf_load_html_response)
BR (1) BR112017005104B1 (enrdf_load_html_response)
CA (1) CA2957868C (enrdf_load_html_response)
EA (1) EA201790796A8 (enrdf_load_html_response)
IL (1) IL250823A0 (enrdf_load_html_response)
MX (1) MX2017004652A (enrdf_load_html_response)
SG (1) SG11201701184WA (enrdf_load_html_response)
WO (2) WO2016055792A1 (enrdf_load_html_response)

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EP3204388B1 (en) * 2014-10-10 2018-12-12 Pulmocide Limited Novel 5,6-dihydro-4h-benzo[b]thieno-[2,3-d]azepine derivatives
EP3233867B1 (en) 2014-12-18 2018-10-17 Pulmocide Limited 4,5-dihydro-6h-thieno[3,2-d]benzazepine derivatives and their use to treat respiratory syncytial virus (rsv) infections
JP7112324B2 (ja) 2015-07-22 2022-08-03 エナンタ ファーマシューティカルズ インコーポレイテッド Rsv阻害剤としてのベンゾジアゼピン誘導体
US20170226129A1 (en) 2016-01-15 2017-08-10 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as rsv inhibitors
CN112245429A (zh) * 2016-02-03 2021-01-22 爱尔兰詹森科学公司 用于治疗rsv的组合产品
US10626126B2 (en) * 2016-04-08 2020-04-21 Pulmocide Limited Compounds
US10398706B2 (en) 2017-01-06 2019-09-03 Enanta Pharmaceuticals, Inc. Heteroaryldiazepine derivatives as RSV inhibitors
JP7076459B2 (ja) 2017-02-16 2022-05-27 エナンタ ファーマシューティカルズ インコーポレイテッド ベンゾジアゼピン誘導体の製造プロセス
US10752598B2 (en) 2017-06-07 2020-08-25 Enanta Pharmaceuticals, Inc. Aryldiazepine derivatives as RSV inhibitors
WO2019006295A1 (en) * 2017-06-30 2019-01-03 Enanta Pharmaceuticals, Inc. HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
WO2019006291A1 (en) * 2017-06-30 2019-01-03 Enanta Pharmaceuticals, Inc. HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
US10881666B2 (en) 2017-09-29 2021-01-05 Enanta Pharmaceuticals, Inc. Combination pharmaceutical agents as RSV inhibitors
WO2019094903A1 (en) 2017-11-13 2019-05-16 Enanta Pharmaceuticals, Inc. Processes for the resolution of benzodiazepin-2-one and benzoazepin-2-one derivatives
WO2019094920A1 (en) 2017-11-13 2019-05-16 Enanta Pharmaceuticals, Inc. Azepin-2-one derivatives as rsv inhibitors
US10975094B2 (en) 2018-04-11 2021-04-13 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as RSV inhibitors
EP3941525A4 (en) 2019-03-18 2022-12-07 Enanta Pharmaceuticals, Inc. BENZODIAZEPIN DERIVATIVES AS RSV INHIBITORS
WO2020210246A1 (en) * 2019-04-09 2020-10-15 Enanta Pharmaceuticals, Inc, Heterocyclic compounds as rsv inhibitors
PH12022550783A1 (en) 2019-10-04 2023-07-31 Enanta Pharm Inc Antiviral heterocyclic compounds
US11505558B1 (en) 2019-10-04 2022-11-22 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
UY39032A (es) 2020-01-24 2021-07-30 Enanta Pharm Inc Compuestos heterocíclicos como agentes antivirales
US11534439B2 (en) 2020-07-07 2022-12-27 Enanta Pharmaceuticals, Inc. Dihydroquinoxaline and dihydropyridopyrazine derivatives as RSV inhibitors
US11945824B2 (en) 2020-10-19 2024-04-02 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as anti-viral agents
WO2022182861A1 (en) 2021-02-26 2022-09-01 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
AR129003A1 (es) 2022-04-07 2024-07-03 Enanta Pharm Inc Compuestos heterocíclicos antivirales
US12162857B2 (en) 2022-04-27 2024-12-10 Enanta Pharmaceuticals, Inc. Antiviral compounds

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JP2011509261A (ja) * 2008-01-07 2011-03-24 シンタ ファーマシューティカルズ コーポレーション 炎症および免疫関連用途向けの化合物
WO2011005842A1 (en) * 2009-07-09 2011-01-13 Gilead Sciences, Inc. Anti-rsv compounds
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US20170226129A1 (en) 2016-01-15 2017-08-10 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as rsv inhibitors
CN112245429A (zh) 2016-02-03 2021-01-22 爱尔兰詹森科学公司 用于治疗rsv的组合产品
WO2019006295A1 (en) 2017-06-30 2019-01-03 Enanta Pharmaceuticals, Inc. HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
WO2019006291A1 (en) 2017-06-30 2019-01-03 Enanta Pharmaceuticals, Inc. HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS

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JP6675407B2 (ja) 2020-04-01
AU2015329789A1 (en) 2017-03-09
EP3204388A1 (en) 2017-08-16
IL250823A0 (en) 2017-04-30
EA201790796A8 (ru) 2018-10-31
BR112017005104B1 (pt) 2022-08-23
US10273249B2 (en) 2019-04-30
EP3204389B1 (en) 2019-06-26
BR112017005104A2 (pt) 2017-12-05
US10472375B2 (en) 2019-11-12
US9926335B2 (en) 2018-03-27
EA201790796A1 (ru) 2017-09-29
WO2016055792A1 (en) 2016-04-14
US20190202841A1 (en) 2019-07-04
JP2017531038A (ja) 2017-10-19
US9732098B2 (en) 2017-08-15
US10189863B2 (en) 2019-01-29
EP3204388B1 (en) 2018-12-12
US20170305935A1 (en) 2017-10-26
CA2957868A1 (en) 2016-04-14
AU2015329789B2 (en) 2019-09-26
US20180179228A1 (en) 2018-06-28
WO2016055791A1 (en) 2016-04-14
US10035810B2 (en) 2018-07-31
US20170190718A1 (en) 2017-07-06
CA2957868C (en) 2023-02-28
CN106852144A (zh) 2017-06-13
EP3204389A1 (en) 2017-08-16
US20170355717A1 (en) 2017-12-14
MX2017004652A (es) 2017-06-19
CN106852144B (zh) 2019-08-30
US20180319820A1 (en) 2018-11-08
SG11201701184WA (en) 2017-03-30
JP2017531039A (ja) 2017-10-19

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