KR20170047589A - Composition for improving conditions of scalp and hair and manufacturing method thereof - Google Patents

Composition for improving conditions of scalp and hair and manufacturing method thereof Download PDF

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KR20170047589A
KR20170047589A KR1020150147892A KR20150147892A KR20170047589A KR 20170047589 A KR20170047589 A KR 20170047589A KR 1020150147892 A KR1020150147892 A KR 1020150147892A KR 20150147892 A KR20150147892 A KR 20150147892A KR 20170047589 A KR20170047589 A KR 20170047589A
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natural material
care composition
ginkgo biloba
scalp care
scalp
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박두헌
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주식회사 에디쁘
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D9/00Compositions of detergents based essentially on soap
    • C11D9/04Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D9/00Compositions of detergents based essentially on soap
    • C11D9/04Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
    • C11D9/22Organic compounds, e.g. vitamins
    • C11D9/38Products in which the composition is not well defined
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/413Nanosized, i.e. having sizes below 100 nm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/82Preparation or application process involves sonication or ultrasonication

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Abstract

The present invention relates to a scalp care composition and a method of manufacturing the same, and more particularly, to a scalp care composition and a method of manufacturing the same that are capable of collecting a henna extract and a functional natural material into nanoparticles to maintain long- And a manufacturing method thereof.
The method for preparing a scalp care composition according to the present invention comprises preparing a natural material powder (S1) for obtaining a natural material in a powder form, mixing the powdered henna extract with 70 to 80% by weight of the natural material powder and 20 to 30% (S2) of pulverizing the mixture to 1 to 50 nm, and a step (S3) of producing nanoparticles by dispersing the pulverized mixture in the base solution to prepare nanoparticles.

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a scalp care composition,

The present invention relates to a scalp care composition and a method of manufacturing the same, and more particularly, to a scalp care composition and a method of manufacturing the same that are capable of collecting a henna extract and a functional natural material into nanoparticles to maintain long- And a manufacturing method thereof.

Hair protects the human body from external impacts. It has the function of discharging unnecessary heavy metals such as arsenic, mercury and zinc from the body to the outside of the body. It also creates a new image and creates a cosmetic aspect that creates its own personality and confidence. I have.

On average, the number of human hair is about 100,000 to 120,000, and it has a hair cycle / hair cycle called a growing period, a regenerating period, and a rest period.

During the growing period, hair growth is prolonged by the proliferation of hair cells, and it takes about 3 ~ 6 years to grow with nutrients. 80 ~ 90% of hair in the whole scalp is growing period.

In the retrograde period, the production of the blastocyst is stopped for 2 to 3 weeks and the hair follicles are rapidly contracted, and 1 to 5% of the hair in the entire scalp is a retrograde.

During the rest period, the hair completely stops and the hair naturally falls off, and the hair is pulled up by the growing hair, or the hair is pulled out by external factors such as combing and shampoo. 4 to 14% of the hair in the entire scalp corresponds to the resting period.

When the hair loss phenomenon appears, the growth period becomes shorter and the retrograde period where the hair follicle shrinks becomes faster. In the case of hair loss after delivery, the ovary is omitted, and the hair is transferred from the growing period to the resting period. For people who start hair loss, the rate of dormant hair is increased, and the dormant hair is more than 20% or more than 100 pieces per day.

Hair loss is mainly caused by dihydrotestosterone (DHT), which strongly stimulates hair follicle cells to shrink hair follicles and thereby delay hair growth.

In addition, it is known that the acquired environment is combined with genetic factors to cause hair loss. That is, factors such as stress, frequent hair styling, side effects of hair products such as shampoo and rinse may cause hair loss.

There are methods of treating hair loss, such as taking medicines, hair transplantation, laser and high frequency treatment. However, since these methods are expensive and side effects may occur, scalp and hair nutrients that can be easily and conveniently applied in daily life are used .

Korean Patent Laid-Open No. 10-2013-0059640 (composition for preventing hair loss or promoting hair growth) is a composition for improving hair and scalp condition containing at least one yeast fermented product of ginseng, ginseng, dansam, ≪ / RTI >

Henna is a Lythraceae plant native to Egypt, India, and Arabia, which is a high temperature and arid region, and is known as Lawsonia inermis.

Its main ingredient is Lawsone (2-hydroxy 1,4-naphathoquinone), which binds to proteins, restoring the damaged keratin layer of hair to make hair shiny and healthy. I have to pray.

In addition, henna has the advantage of being able to use pregnant women because it is less irritant and toxic, and it has the effect of preventing depression by lowering heat of scalp, eliminating itching and dandruff, supplying nutrients such as minerals, Baldness is effective in treating.

Thus, henna is harmless to the human body and has been used as a composition for improving hair and scalp, in which the powder is simply applied to the scalp by spreading it in water.

However, since henna is vulnerable to oxidation, the effective ingredient may be destroyed quickly when exposed to the external environment (moisture, air, etc.), and the skin absorption capacity is low so that the effect is not maximized.

The above-mentioned patent documents and conventional scalp improving compositions are merely a mixture of natural materials and chemical materials, and most of them do not consider efficacy persistence, scalp absorption power and penetration power of the active ingredient.

Korean Patent Publication No. 10-2013-0059640 (composition for preventing hair loss or promoting hair growth)

DISCLOSURE OF THE INVENTION The object of the present invention to solve the above problems is to provide a scalp care composition and a method of manufacturing the same that collect henna extract and functional natural material in nanoparticles to maintain long- .

Another object of the present invention is to provide a scalp care composition with improved scalp absorbing power and penetration power and a method for producing the same.

In order to solve the above-described problems, the present invention provides a method for producing a scalp care composition,

A natural material powder preparation step (S1) of obtaining a natural material in powder form; (S2) of pulverizing a mixture of 70 to 80% by weight of the natural material powder and 20 to 30% by weight of the powdery henna extract to 1 to 50 nm; Dispersing the pulverized mixture in a base solution to prepare nano-coated particles (S3).

The natural material powder preparation step (S1) includes a natural material pulverization step (S11) of pulverizing the natural material; A heating step (S12) in which the ground natural material is immersed in purified water or alcohol and heated; A cooling step (S13) of cooling the immersion liquid in which the natural material is immersed; An ultrasonic extraction step (S14) of applying an ultrasonic wave of 10 to 60 kHz to the cooled immersion liquid to extract an effective ingredient; And a lyophilization step (S15) of lyophilizing the extracted liquid from which the active ingredient has been extracted to obtain a powdery form.

The nanoparticle preparation step (S3) comprises preparing a base solution (S31) by mixing a phospholipid, a fatty acid and an organic solvent to prepare a base solution; A dispersing step (S32) of dispersing the pulverized mixture in the base solution; And a nanoization step (S33) of collecting the active ingredient by performing the process 3 to 5 times at 600 to 1200 bar using a mixed solution of a pulverized mixture and a high-pressure emulsifier.

The dispersing step (S32) is characterized in that ultrasonic waves of 25 to 40 kHz are irradiated for 10 to 30 minutes.

The natural materials may be selected from the group consisting of antler, licorice, ginseng, seaweed, sorghum, ginseng, white ginseng, ginger, garlic, green tea, emerald, Mushroom, mushroom, willow mushroom, vitamin tree, sunflower root, tiger pod leaf, perennial plant, insect repellant, saururus, horsetail, gooseberry, plum, coffee, oyster, colostrum, eggs, nuts, legumes, royal jelly, aloe vera, , ≪ / RTI > Hanshikucho, and evening primrose.

The natural material is characterized by further containing 10 to 25% by weight of a mineral material for 100% by weight of the total natural material to radiate far-infrared rays to increase the absorption power of the effective ingredient.

The mineral material is characterized by being at least one of bentonite, zeolite, pearlite, vermiculite, tourmaline, moss, kaolin.

In order to solve the above-mentioned problems, the scalp care composition of the present invention comprises a mixture of 70 to 80% by weight of the natural material powder and 20 to 30% by weight of a powdery henna extract and pulverizing the mixture to 1 to 50 nm, Is dispersed in a base solution to form nanoparticles.

The natural material powder is obtained by pulverizing a natural material, immersing the pulverized natural material in purified water or alcohol, heating the immersed liquid immersed in the natural material, and applying an ultrasonic wave of 10 to 60 kHz to the cooled immersion liquid, And then lyophilized to obtain a powder.

The nanoparticles are prepared by dispersing the pulverized mixture in a base solution containing a phospholipid, a fatty acid and an organic solvent, and then performing the pulverization at 600 to 1200 bar for 3 to 5 times using a high-pressure emulsifier to collect the active ingredient.

And the pulverized mixture is irradiated with ultrasound at 25 to 40 kHz for 10 to 30 minutes to disperse.

The natural materials may be selected from the group consisting of antler, licorice, ginseng, seaweed, sorghum, ginseng, white ginseng, ginger, garlic, green tea, emerald, , Camellia mushroom, willow matsutake mushroom, vitamin tree, sunflower root, tiger mulberry leaf, perennial plant, bug bug, Sambucoptera, bamboo shoot, gooseberry, plum, coffee, oyster, colostrum, egg, nuts, beans, royal jelly, aloe vera , Japanese lobules, hanjiccho, and evening primrose.

The natural material is characterized by further containing 10 to 25% by weight of a mineral material for 100% by weight of the total natural material to radiate far-infrared rays to increase the absorption power of the effective ingredient.

The mineral material is characterized by being at least one of bentonite, zeolite, pearlite, vermiculite, tourmaline, moss, kaolin.

As described above, according to the scalp care composition and the method for producing the same according to the present invention, the henna extract and the functional natural material are captured on the nanoparticles, and the effective ingredient is retained for a long time without being damaged.

Further, according to the scalp care composition and the manufacturing method thereof according to the present invention, there is an effect of enhancing the scalp absorbency and penetration strength.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a flow chart illustrating a method of preparing a scalp care composition in accordance with the present invention. FIG.
2 is a flow chart showing steps of preparing a natural material powder according to the present invention.
FIG. 3 is a flow chart showing steps of manufacturing nanoparticles according to the present invention. FIG.
FIG. 4 is a graph comparing the penetration of active ingredients into the scalp improving composition according to the present invention and the conventional scalp improving composition. FIG.

Specific features and advantages of the present invention will be described in detail below with reference to the accompanying drawings. The detailed description of the functions and configurations of the present invention will be omitted if it is determined that the gist of the present invention may be unnecessarily blurred.

The present invention relates to a scalp care composition and a method of manufacturing the same, and more particularly, to a scalp care composition and a method of manufacturing the same that are capable of collecting a henna extract and a functional natural material into nanoparticles to maintain long- And a manufacturing method thereof.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings.

FIG. 1 is a flow chart showing a method of preparing a scalp care composition according to the present invention. FIG. 1 is a flowchart illustrating a method of preparing a scalp care composition according to the present invention. To 80% by weight of a powdery henna extract and 20 to 30% by weight of a powdery henna extract is pulverized to a particle size of 1 to 50 nm; and a step (S2) of dispersing the pulverized mixture in a base solution to form nanoparticles And a manufacturing step (S3).

In the natural material powder preparation step (S1), a natural material is obtained in powder form, and the natural material is added as a functional raw material for improving the blood circulation of the scalp and supplying nutrients to scalp and hair.

The natural materials may be selected from the group consisting of antler, licorice, ginseng, seaweed, wormwood, ginseng, black tea, ginger, garlic, green tea, hwanggi, It has been found that the seeds of camellia, gingko mushrooms, willow mats, vitamins, sunflower roots, tiger pussy willow, perennials, Aloe vera, Liliaceae, Hansikucho, and Evening Primrose.

Among them, sunflower roots and tiger pods are effective in purifying heavy metals (cadmium, zinc, etc.), and are resistant to toxic substances and decomposition of pollutants.

Pyrethrin and Cinerin are the main constituents of the bug bug, and they have toxic substance decomposition and insecticidal effect while they are harmless to human body.

Baeknyoncho contains antioxidant phytocellatin component, which has the effect of detoxifying and releasing heavy metals. Saururus chinensis and Hwasungcho are anti-inflammatory by the action of quercetin and quercitrin.

Acanthocytes B and D, and plum acacia, picric acid to decompose the toxic substances, and protects the scalp.

In addition, the enzyme (AaeAPO) extracted from pine mushroom is classified as Aromatic peroxygenase (APO), and it is a type of fungal enzyme, which is not destroyed or lost its activity even when placed in an isolated state in the intracellular environment, Is very good and has the ability to decompose toxic substances. In particular, the effect of removing methylimidazole, which is a carcinogenic aromatic compound, to remove toxicity is significant.

Catechin in green tea inhibits the production of dihydrotestosterone (DHT) hormone that causes hair loss, and other tannins prevent hair loss by tightening the pores of the scalp.

Caffeine added to coffee promotes intracellular metabolism so that the hair follicles can be properly nourished and the energy source of the hair is slowed down.

The oysters are rich in zinc, which activates the metabolism of cells and tissues, and removes free radicals that adversely affect hair. In addition, it is involved in the synthesis of collagen to prevent aging of thinning hair.

Lactoferrin added to colostrum is combined with proteins to restore damaged hair, remove active oxygen with powerful antioxidants, and enhance scalp immunity.

Eggs and nuts are rich in vitamin B3, called Niacin or Nicotinic acid. Vitamin B3 promotes hair thickening and hair growth. In addition, it is rich in biotin to alleviate the inflammation of the scalp, and prevents the break of hair.

In addition, saponin is abundant in Hwanggi, Gugija, Hassuo, Camellia, and Ginseng, promoting hair growth by promoting circulation of scalp.

Flavonoid is abundant in beans, ginkgo, and royal jelly, which cleanses the scalp and alleviates the growth of dandruff and germs and fungi, thereby preventing hair loss and aging of scalp and hair. prevent.

Aloe vera, Japanese leaf, and Hanchuncho strengthen the scalp's protective layer, preventing hair from falling off easily.

Evening primrose suppresses the sebaceous secretion of the scalp, thereby enhancing nutrition and moisturizing the scalp.

The marijuana has the highest antioxidant index among berries, and is rich in polyphenols and anthocyanins, and thus has excellent immunity and antioxidant effects.

Blossom mushroom is rich in beta-glucan to remove the active oxygen of the scalp to prevent aging of the scalp and improve blood circulation. In addition, it is known that the moisture content is higher than that of hyaluronic acid, thereby preventing dandruff.

Vitamin tree (H. rhamnoides) is a deciduous shrub belonging to the barley family originating in China, Mongolia, etc. Its leaves and fruits contain vitamins and amino acids. It has immunity and anti-inflammatory effect. Polyphenols, tocopherols, carotenoids, flavonoids and the like have been reported to be contained.

The whitewater speculum is rich in betulin, preventing aging, and has anti-inflammatory and antiviral effects.

In addition, the natural material may further include a mineral material for emitting far infrared rays to enhance the absorption power, and is included in an amount of 10 to 25% by weight based on 100% by weight of the entire natural material.

The mineral material may further be included in the natural material powder in a mixture grinding step (S2), which will be described in detail below, to be mixed with and crushed with the henna extract.

The mineral material is characterized by being at least one of bentonite, zeolite, pearlite, vermiculite, tourmaline, moss, kaolin.

More specifically, the mineral material has a high cation exchange ability, adsorptivity and swelling property, and the adsorbing minerals include 66 kinds of natural minerals such as silicon dioxide, aluminum oxide, magnesium oxide, iron oxide, calcium oxide, calcium hydroxide, And it absorbs the nutrients by the occlusion action of the far-infrared rays and the anions that they emit.

That is, not only the time for applying the scalp care composition can be shortened, but also the environment in which the active ingredient and the nutritional ingredient can be absorbed is more improved.

In addition, it absorbs various harmful substances such as waste products, sebum, heavy metals, etc., and cleanses hair, gives elasticity, and supplies nutrition simultaneously.

If the amount of the mineral material is less than 10% by weight, the effect is insignificant. When the amount of the mineral material is more than 25% by weight, It is preferable that the mixing property with the natural material is poor and does not deviate from the above range.

2 is a flow chart showing steps of preparing a natural material powder according to the present invention.

In the natural material powder preparation step (S1), a natural material is obtained in the form of powder, and the natural material powder preparation step (S1) comprises a natural material pulverization step (S11) of pulverizing the natural material and a pulverizing natural material in purified water or alcohol (S14) for cooling the immersion liquid in which the natural material is immersed; an ultrasonic extraction step (S14) for applying an ultrasonic wave of 10 to 60 kHz to the cooled immersion liquid to extract an effective ingredient; And a lyophilization step (S15) of lyophilizing the extract solution from which the active ingredient is extracted to obtain a powdery form.

In the natural material pulverization step (S11), the surface area of the natural material is increased to increase the extraction efficiency of the natural material, and the pulverized material is pulverized to a size of 0.5 to 1 cm.

In the heating step (S12), the crushed natural material is immersed in purified water or alcohol and heated.

More specifically, purified water or alcohol can be used as the immersion liquid for extraction, and in the case of purified water, it can be used for extracting polysaccharide components, flavonoids and other water-soluble components of natural materials.

In the case of alcohol, methyl alcohol or ethyl alcohol can be used, and it can be used for extracting antioxidative and physiologically active substances of natural materials. Alcohol can be used relatively comprehensively as compared to purified water and is easy to extract various components.

In the heating step (S12), the natural material and the immersion liquid (purified water or alcohol) are immersed and mixed at a ratio of 1: 2 to 3, and the mixture is heated at a temperature of 100 to 130 ° C for 30 minutes to 1 hour, The active ingredient is firstly extracted.

When the mixing ratio of the natural material and the immersion liquid is less than 1: 2, the immersion liquid does not supply sufficient heat energy to the natural material, so that the extraction efficiency (Evaporation) is required because the concentration of the extract is lowered when the ratio is more than 1: 3, it is preferable that the concentration does not deviate from the above range.

If the heating temperature is lower than 100 ° C, it is difficult to supply sufficient heat energy to the natural material, so that the extraction efficiency is lowered. If the heating temperature exceeds 130 ° C, the active ingredient may be destroyed.

In the cooling step (S13), the natural material is cooled in an immersed state of the natural material. In this step, the heating is interrupted for 20 to 30 minutes, and the effective ingredient can be slowly extracted without being destroyed by the remaining heat.

There are various methods for extracting the active ingredient from natural plants, such as hot water extraction, pressurized heating extraction, and reflux cooling extraction. However, these conventional methods have limitations in extraction yield.

In the ultrasonic extraction step (S14), ultrasonic waves of 10 to 60 kHz are applied to the immersed and cooled natural material to extract the active ingredient secondarily. By applying ultrasonic waves, the extraction yield of the active ingredient of the natural material can be increased , It is possible to remove unnecessary foreign substances such as iron ions and nitrites generated in the extraction process.

It is preferable that the ultrasonic wave is applied in the range of 10 to 60 kHz. If the ultrasonic wave is less than 10 kHz, it is difficult to expect the effect. If the ultrasonic wave is more than 60 kHz, the effective ingredient may be broken.

In the freeze-drying step (S15), the extract is lyophilized to obtain a powder.

More specifically, the extract is subjected to separation (4000 to 5000 rpm, 3 to 10 minutes) of the supernatant using a centrifugal separator (Sorvall, USA), and the separated extract is lyophilized and centrifuged at -50 to- And lyophilized for 24 hours to obtain an extract powder.

The mixture pulverization step (S2) is a step of pulverizing a mixture of natural material powder and henna extract prepared in the natural material powder preparation step (S1) to 1 to 50 nm.

The mixture pulverization step (S2) is a step prior to the nanoparticle preparation step (S3), in which the particle size distribution of the natural material powder and the henna extract is made uniform and dispersed more uniformly in the nanoparticle preparation step (S3) The natural material powder and the henna extract can be collected at a more uniform ratio.

The henna extract is preferably dried or powdered in consideration of the mixing property with the natural material powder, and preferably 20 to 30% by weight, %, It is difficult to expect the effect. When it is added in an amount exceeding 30% by weight, it can be colored on the scalp, so that it is preferable not to deviate from the range.

The pulverizing method may be a wet method and a dry method, and the method thereof is not limited. However, in case of the wet method, it is preferable to use the dry method because an additional post-treatment (drying) is required.

On the other hand, the intercellular lipids constituting the scalp are between 150 and 400 nm, and the size of particles for penetration and absorption into the scalp should be less.

When considering the correlation of the size of the particles to be absorbed on the scalp and the increase of the particle size in the nanoparticles produced in the nanoparticle preparation step (S3), the size of the pulverization is preferably 1 to 50 nm.

FIG. 3 is a flow chart showing steps of manufacturing nanoparticles according to the present invention.

In the nanoparticle preparation step (S3), the mixture pulverized in the mixture pulverization step (S2) is dispersed in the base solution to prepare nanocomposite particles.

The nano-liposome according to the present invention is a nano-liposome. Since nanoliposome has both hydrophilicity and lipophilicity and is structurally similar to a skin biolipid film, the skin penetration effect is good.

More specifically, the liposome is a lipid-bilayer membrane formed by phospholipid, which is a constituent of a biochemical membrane of amphipathic lipid. The membrane structure of the liposome is similar to that of the cell membrane, And transferring the active ingredient through the intracellular transfer.

The nanoparticle preparation step (S3) includes a base solution preparation step (S31) for preparing a base solution by mixing phospholipid, fatty acid and organic solvent, a dispersion step (S32) for dispersing the ground mixture in the base solution, And a nanoization step (S33) of collecting the active ingredient by performing the dispersed mixture solution at a high pressure emulsifier at 600 to 1,200 bar three to five times.

In the base solution preparation step (S31), a phospholipid, a fatty acid, and an organic solvent are mixed to prepare a base solution.

Wherein the phospholipid is selected from the group consisting of egg yolk lecithin, soy lecithin, lysolecithin, sphingomyelin, phosphatidylic acid, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, phosphatidylethanolamine, diphosphatidylglycerol, cardiolipin and plasmarogens Lt; / RTI >

The fatty acid may be any one or more of lauric acid, palmitic acid, stearic acid, oleic acid, and linoleic acid, and the organic solvent may include propylene glycol, dipropylene glycol, Propanediol, isopropylene glycol, pentylene glycol, erythritol, xylitol, sorbitol and mixtures thereof with distilled water.

The surfactant may be an anionic, cationic, amphoteric or nonionic surfactant. The oil may be selected from the group consisting of paraffin oil, ester oil, silicone oil, corn oil, soybean oil Etc. may be used.

These are uniformly dissolved at 70 to 80 캜 to prepare a base solution.

When the powder is nano-sized, the inter-particle distance becomes extremely short, and the inter-particle van der Waals force is much larger than the particle's own gravity, resulting in particle mutual agglomeration.

The nanoparticles have high surface energy on the nanoparticle surface because they absorb a lot of energy in the nanoporous process, and the particles try to reach a stable state through mutual cohesion to lower the surface energy.

In the dispersing step (S32), the pulverized powders are put into the base solution, and the van der Waals force between the particles is dispersed so that the powders do not aggregate with each other and are uniformly dispersed so that the pulverized mixture in the nanoparticles is relatively uniformly collected So that the nanoparticle size distribution can also be uniformly formed.

At this time, ultrasonic waves of 25 to 40 kHz are irradiated for 10 to 30 minutes. When the frequency is less than 25 kHz, it is difficult to disperse van der Waals force, so that agglomeration may occur between powders or the size of nanoparticles may increase. The nanoparticles can be formed to have a small size with good dispersibility, but it is preferable that the nanoparticles do not deviate from the above range because the morphology thereof is poor and it is difficult to have a stable shape.

It is preferable that the irradiation time does not deviate from the above range for the same reason as the ultrasonic intensity.

In the nanoization step (S33), the mixed solution in which the ground mixture is dispersed is subjected to 3 to 5 times at 600 to 1200 bar using a high-pressure emulsifier to collect the active ingredient.

When the pressure and the number of times are less than the range, it is difficult to form a nanoparticle with a small size, and the particle size distribution is also very wide, thereby increasing the possibility of causing creaming phenomenon in the composition. It is preferable not to deviate from the above range because there is no significant improvement in aspect.

The nanoparticles prepared in the nanoparticle preparation step (S3) are water-soluble and lipid-soluble. In order to apply the scalp care composition prepared according to the present invention to the scalp, a predetermined processing step (water or oil , The active ingredient contained therein is exposed to the outside of the nanoparticle as the nano-particle membrane is destroyed.

The scalp care composition according to the present invention is characterized in that it is produced by the above-described manufacturing method, and the henna extract and the functional natural material are collected in the nanoparticles so that the effective ingredient is kept intact for a long time, .

The scalp care composition is prepared by pulverizing a mixture of 70 to 80% by weight of the natural material powder and 20 to 30% by weight of the powdery henna extract into 1 to 50 nm and dispersing the pulverized mixture in the base solution Nano-coated nanoparticles.

The natural material powder is obtained by pulverizing a natural material, immersing the pulverized natural material in purified water or alcohol, heating the immersed liquid immersed in the natural material, and applying an ultrasonic wave of 10 to 60 kHz to the cooled immersion liquid, And then lyophilized to obtain a powder.

The nanoparticles are prepared by dispersing the pulverized mixture in a base solution prepared by mixing the dissolved oily phase with an ethanol phase which has been heated in advance, and then pulverizing the pulverized mixture using a high-pressure emulsifier at 600 to 1200 bar for 3 to 5 times to collect the active ingredient .

And the pulverized mixture is irradiated with ultrasound at 25 to 40 kHz for 10 to 30 minutes to disperse.

The natural materials may be selected from the group consisting of antler, licorice, ginseng, seaweed, mugwort, ginseng, white ginseng, ginger, garlic, green tea, emerald, , Camellia mushroom, willow matsutake mushroom, vitamin tree, sunflower root, tiger mulberry leaf, perennial plant, bug bug, Sambucoptera, bamboo shoot, gooseberry, plum, coffee, oyster, colostrum, egg, nuts, beans, royal jelly, aloe vera , Japanese lobules, hanjiccho, and evening primrose.

The natural material is characterized by further containing 10 to 25% by weight of a mineral material for 100% by weight of the total natural material to radiate far-infrared rays to increase the absorption power of the effective ingredient.

The mineral material is characterized by being at least one of bentonite, zeolite, pearlite, vermiculite, tourmaline, moss, kaolin.

FIG. 4 is a graph comparing the penetration power of the scalp improving composition according to the present invention and the conventional scalp improving composition, wherein (a) is a conventional scalp improving composition and (b) is a scalp controlling composition according to the present invention.

Conventional scalp improving compositions contain merely functional natural materials or chemical raw materials in the composition and do not consider the size of the particles. Thus, even when a good functional raw material is used, there is a limit to maximizing the efficiency.

However, by capturing the functional natural material, the henna extract and the mineral material into the nanoparticles, the scalp care composition according to the present invention can maintain the active ingredient for a long period without being damaged or destroyed, and can enhance the scalp absorbing power and penetration power, .

The nanoparticles of the scalp care composition according to the present invention are amphipathic substances having both water-solubility and liposolubility. When the nanoparticles are subjected to a predetermined processing step (when water or oil is added before use) to apply the scalp care composition to the scalp, The active ingredient contained in the nanoparticles may be gradually exposed to the outside of the nanoparticle so that the active ingredient can be absorbed into the scalp.

Or the frictional pressure generated in the course of applying the scalp care composition according to the present invention to the scalp (application and massage), the nanoparticles may burst and the active ingredient may be exposed and absorbed to the outside.

The scalp care composition of the present invention can be used as a hair dye, a soap, a shampoo, a rinse, a body wash, a foam cleansing, a bath agent, a lotion, a skin,

For example, when the soap and water react with each other in the same manner as described above, the effective ingredient of the nanoparticles of the scalp care composition may be mixed with the external The effective ingredient can be absorbed into the skin and scalp.

Also, since the hair care composition according to the present invention contains a natural material (such as henna) having a tannin component, it can be used in a hair dyeing agent. have.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is clearly understood that the same is by way of illustration and example only and is not to be taken as limiting the scope of the present invention. The present invention can be variously modified or modified. The scope of the invention should, therefore, be construed in light of the claims set forth to cover many of such variations.

Claims (16)

A natural material powder preparation step (S1) of obtaining a natural material in powder form;
(S2) of pulverizing a mixture of 70 to 80% by weight of the natural material powder and 20 to 30% by weight of the powdery henna extract to 1 to 50 nm;
(S3) of dispersing the pulverized mixture in a base solution to prepare nanoparticle particles; and
≪ / RTI >
The method according to claim 1,
The natural material powder preparation step (S1)
A natural material pulverizing step (S11) of pulverizing the natural material;
A heating step (S12) in which the ground natural material is immersed in purified water or alcohol and heated;
A cooling step (S13) of cooling the immersion liquid in which the natural material is immersed;
An ultrasonic extraction step (S14) of applying an ultrasonic wave of 10 to 60 kHz to the cooled immersion liquid to extract an effective ingredient;
And a lyophilization step (S15) of lyophilizing the extracted liquid from which the active ingredient has been extracted to obtain a powdery form
≪ / RTI >
The method according to claim 1,
The nanoparticle preparation step (S3)
A base solution preparing step (S31) of preparing a base solution by mixing phospholipid, fatty acid and organic solvent;
A dispersing step (S32) of dispersing the pulverized mixture in the base solution;
(S33) which is carried out 3 to 5 times at 600 to 1,200 bar by using a high-pressure emulsifier in which the pulverized mixture is dispersed to collect the active ingredient
A method for preparing a scalp care composition.
The method of claim 3,
The dispersing step (S32)
And ultrasonic waves of 25 to 40 kHz are irradiated for 10 to 30 minutes
≪ / RTI >
The method according to claim 1,
The natural material
Ginkgo biloba, Ginkgo biloba, Ginkgo biloba, Ginkgo biloba, Ginkgo biloba, Ginkgo biloba, Ginkgo biloba, Ginkgo biloba, Ginkgo biloba, Ganoderma lucidum, Ginseng, Seaweed, It is also known as a mushroom, a mushroom of willow, a vitamin tree, a sunflower root, a tiger prawn leaf, a perennial plant, a pest repellant, a saururus, a perennial plant, a gooseberry, a plum, a coffee, an oyster, a colostrum, It is characterized in that it is any one or more of Hansikucho and Evening Primrose
A method for preparing a scalp care composition.
The method according to claim 1,
The natural material
Characterized in that it further comprises 10 to 25% by weight of a mineral material for 100% by weight of the total natural material for radiating far-infrared rays to increase absorption power of the effective ingredient
A method for preparing a scalp care composition.
The method according to claim 6,
The mineral material
Bentonite, zeolite, perlite, vermiculite, tourmaline, moss, kaolin.
A method for preparing a scalp care composition.
A scalp care composition comprising a natural material and a henna extract,
The scalp care composition comprises
A mixture of 70 to 80% by weight of the natural material powder and 20 to 30% by weight of a powdery henna extract is pulverized to 1 to 50 nm, and the nanocarbonized nanoparticles prepared by dispersing the pulverized mixture in a base solution Characterized in that
A scalp care composition.
9. The method of claim 8,
The natural material powder
The natural material is pulverized and the pulverized natural material is immersed in purified water or alcohol and heated. The immersion liquid in which the natural material is immersed is cooled, and an ultrasonic wave of 10 to 60 kHz is applied to the cooled immersion liquid to extract the active ingredient, Characterized in that the
A scalp care composition.
9. The method of claim 8,
The nanoparticles
Wherein the pulverized mixture is dispersed in a base solution containing a phospholipid, a fatty acid, and an organic solvent, and then the mixture is subjected to 3 to 5 times at 600 to 1200 bar using a high-pressure emulsifier to collect the active ingredient
A scalp care composition.
11. The method of claim 10,
The pulverized mixture
Ultrasonic waves of 25 to 40 kHz are irradiated for 10 to 30 minutes to disperse
A scalp care composition.
9. The method of claim 8,
The natural material
Ginkgo biloba, Ginkgo biloba, Ginkgo biloba, Ginkgo biloba, Ginkgo biloba, Ginkgo biloba, Ginkgo biloba, Ginkgo biloba, Ginkgo biloba, Ganoderma lucidum, Ginseng, Seaweed, It is also known as a mushroom, a mushroom of willow, a vitamin tree, a sunflower root, a tiger prawn leaf, a perennial plant, a pest repellant, a saururus, a perennial plant, a gooseberry, a plum, a coffee, an oyster, a colostrum, It is characterized in that it is any one or more of Hansikucho and Evening Primrose
A scalp care composition.
9. The method of claim 8,
The natural material
Characterized in that it further comprises 10 to 25% by weight of a mineral material for 100% by weight of the total natural material for radiating far-infrared rays to increase absorption power of the effective ingredient
A scalp care composition.
14. The method of claim 13,
The mineral material
Bentonite, zeolite, perlite, vermiculite, tourmaline, moss, kaolin.
A scalp care composition.
9. A soap comprising the scalp care composition of claim 8.
A hair dye containing the scalp care composition of claim 8.
KR1020150147892A 2015-10-23 2015-10-23 Composition for improving conditions of scalp and hair and manufacturing method thereof KR20170047589A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102085741B1 (en) * 2018-12-07 2020-03-06 최미영 Shampoo Containing Coffee Component, and Method for Manufacturing the Same
KR102179610B1 (en) * 2020-04-17 2020-11-18 대구한의대학교산학협력단 Composition for preventing hair loss or promoting hair growth containing essential oil mixture of Coicis semen and Evening Primrose seeds
KR102192317B1 (en) * 2020-04-29 2020-12-21 주식회사 메디컬오 Composition for Skin Soothing Comprising Exosomes Derived from Natural Extracts
KR102217586B1 (en) * 2020-03-18 2021-02-19 이수행 Manufacturing method of natural scalp care
KR102256711B1 (en) * 2020-05-28 2021-05-25 김홍중 Composition for preventing hair loss comprising tormaline and mixed natural herb extracts

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102085741B1 (en) * 2018-12-07 2020-03-06 최미영 Shampoo Containing Coffee Component, and Method for Manufacturing the Same
KR102217586B1 (en) * 2020-03-18 2021-02-19 이수행 Manufacturing method of natural scalp care
KR102179610B1 (en) * 2020-04-17 2020-11-18 대구한의대학교산학협력단 Composition for preventing hair loss or promoting hair growth containing essential oil mixture of Coicis semen and Evening Primrose seeds
KR102192317B1 (en) * 2020-04-29 2020-12-21 주식회사 메디컬오 Composition for Skin Soothing Comprising Exosomes Derived from Natural Extracts
KR102267796B1 (en) * 2020-04-29 2021-06-24 주식회사 메디컬오 Composition for Skin Soothing Comprising Exosomes Derived from Natural Extracts
KR102256711B1 (en) * 2020-05-28 2021-05-25 김홍중 Composition for preventing hair loss comprising tormaline and mixed natural herb extracts

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