KR20160127711A - 유비퀴티닐화 단백질 - Google Patents

유비퀴티닐화 단백질 Download PDF

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Publication number
KR20160127711A
KR20160127711A KR1020167012290A KR20167012290A KR20160127711A KR 20160127711 A KR20160127711 A KR 20160127711A KR 1020167012290 A KR1020167012290 A KR 1020167012290A KR 20167012290 A KR20167012290 A KR 20167012290A KR 20160127711 A KR20160127711 A KR 20160127711A
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South Korea
Prior art keywords
cells
ubiquitinylated
tumor
protein
antigen
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KR1020167012290A
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English (en)
Korean (ko)
Inventor
크리스토퍼 트위티
에릭 레쉐인
버나드 폭스
홍-밍 후
광지에 유
Original Assignee
유비백, 엘엘씨.
프로비던스 헬스 앤드 서비시즈 - 오레곤
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Publication of KR20160127711A publication Critical patent/KR20160127711A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
KR1020167012290A 2013-10-11 2014-10-10 유비퀴티닐화 단백질 Ceased KR20160127711A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361890054P 2013-10-11 2013-10-11
US61/890,054 2013-10-11
PCT/US2014/060180 WO2015054668A1 (en) 2013-10-11 2014-10-10 Ubiquitinylated proteins

Publications (1)

Publication Number Publication Date
KR20160127711A true KR20160127711A (ko) 2016-11-04

Family

ID=52809877

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020167012290A Ceased KR20160127711A (ko) 2013-10-11 2014-10-10 유비퀴티닐화 단백질

Country Status (7)

Country Link
US (1) US10226518B2 (https=)
EP (1) EP3055322B1 (https=)
JP (1) JP6636915B2 (https=)
KR (1) KR20160127711A (https=)
CN (1) CN105934442B (https=)
CA (1) CA2926332A1 (https=)
WO (1) WO2015054668A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104877017A (zh) * 2015-05-06 2015-09-02 东南大学 一种抗肿瘤泛素化蛋白及其提取方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040241140A1 (en) * 2000-11-01 2004-12-02 Pavlakis George N. Expression vectors able to elicit improved immune response and methods of using same
WO2007016340A2 (en) * 2005-07-29 2007-02-08 Providence Health System Defective ribosomal products in blebs (dribbles) and methods of use to stimulate an immune response
WO2007058235A1 (ja) * 2005-11-17 2007-05-24 Medinet Co., Ltd. 融合蛋白質およびその薬学的用途
JP2012039877A (ja) * 2009-04-10 2012-03-01 Fukuoka Univ ユビキチン融合遺伝子およびそれを用いたｄｎａワクチン
EP2608811B1 (en) * 2010-08-27 2015-01-28 Providence Health & Services - Oregon Alumina nanoparticle bioconjugates and methods of stimulating an immune response using said bioconjugates

Also Published As

Publication number Publication date
JP2016534042A (ja) 2016-11-04
EP3055322A4 (en) 2017-06-14
JP6636915B2 (ja) 2020-01-29
WO2015054668A1 (en) 2015-04-16
US20150104477A1 (en) 2015-04-16
US10226518B2 (en) 2019-03-12
CN105934442A (zh) 2016-09-07
CN105934442B (zh) 2020-03-06
CA2926332A1 (en) 2015-04-16
EP3055322A1 (en) 2016-08-17
EP3055322B1 (en) 2019-09-25

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