KR20160096295A - Crickets for improved anti-cancer and food compositions comprising the same - Google Patents
Crickets for improved anti-cancer and food compositions comprising the same Download PDFInfo
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- KR20160096295A KR20160096295A KR1020150017734A KR20150017734A KR20160096295A KR 20160096295 A KR20160096295 A KR 20160096295A KR 1020150017734 A KR1020150017734 A KR 1020150017734A KR 20150017734 A KR20150017734 A KR 20150017734A KR 20160096295 A KR20160096295 A KR 20160096295A
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Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
Abstract
The present invention relates to a cricket with enhanced anticancer effect and a food composition containing the cricket. More particularly, the present invention relates to a cricket which is produced by raising crickets so as to increase the content of active ingredients involved in anti- The present invention also relates to a cricket with enhanced anticancer effect and a food composition containing the cricket.
The cricket with improved anticancer effect and the food composition containing the same according to the present invention are characterized by comprising 14 to 16 parts by weight of tomato, 14 to 16 parts by weight of garlic, 14 to 16 parts by weight of garlic, 14 to 16 parts by weight of squash, A diet containing 14 to 16 parts by weight of spinach, 14 to 16 parts by weight of sweet potato, and 14 to 16 parts by weight of chungkukjang was fed to cricket three times a day, and 0.005 to 0.02 g was fed per crust, The animals were housed in a cricket-boosted cricket containing an anticancer effect containing ~ 0.025%, vitamin B 1.7-2.3%, vitamin C 1.2-1.5%, vitamin E 0.25-0.35%, beta carotene 1-2% and lycopene 0.3-0.5% , And a cricket with the enhanced anticancer effect is used to produce a food composition.
Description
The present invention relates to a cricket with enhanced anticancer effect and a food composition containing the cricket. More particularly, the present invention relates to a cricket which is produced by raising crickets so as to increase the content of active ingredients involved in anti- The present invention also relates to a cricket with enhanced anticancer effect and a food composition containing the cricket.
The insect is mainly regarded as a pest and has been focused on the control of these insects. In recent years, some insects have been used to industrially use insect bioactive materials or to develop pharmaceuticals while newly recognizing the diversity and characteristics of insects.
Among them, crickets are rich in unsaturated fatty acids including omega-3 fatty acids, and contain high levels of protein and chitin / chitosan. Therefore, adding cricket extract to livestock feed increases the level of polyunsaturated fatty acids and meat quality .
These crickets contain nutrients that are highly effective in health, including minerals, vitamins, and proteins. Proteins include 17 amino acids, including all nine essential amino acids.
Specifically, the nine essential amino acids are amino acids that can not be synthesized in the body and must be ingested from foods.
Leucine is a major constituent of all protein components and is related to liver function. It directly participates in growth hormone and bone formation, promotes calcium absorption, prevents osteoporosis by nitrogen equilibrium maintenance action, and leucine and arginine together When ingested, they absorb and compete to increase immunity. It also alleviates cataract symptoms due to hyperglycemia, inhibits arterial blood formation of lipoprotein with proline, participates in the production of antibodies, enzymes and hormones, participates in collagen formation, restores muscle loss and restores tissue damage, It plays a role of fatigue recovery, vitality enhancement and blood sugar reduction. Generally, there are a lot of vegetable foods such as ham, cheese, corn and soybeans.
The isoleucine decomposes carbohydrate, fat and protein to produce energy, produces hemoglobin, regulates blood sugar, is involved in muscle formation and repair, enhances nutritional supply and endocrine function, and promotes metabolic syndrome And to restore and promote post-operative body function. It is commonly found in salmon, chicken, beef, and milk.
It is the main component of the valine muscle protein, which increases muscle strength, helps mental stability, balances muscle strength and insulin secretion, and is rich in peanuts, beans, mushrooms and meat.
The phenylalanine produces chemicals that transmit signals between nerve cells and the brain, stimulates secretion of thyroid hormones, alleviates chronic pain, reduces pain on fasting, acts as an antidepressant, learns and memorizes brain activity Lt; / RTI >
Threonine is a component of collagen, elastin, and enamel protein. It protects liver fat accumulation to prevent fatty liver, helps digestion function smoothly, participates in metabolism and assimilation, Helps the immune system.
Methionine is an essential nutrient for hypertensive patients and reduces liver fat, because it prevents hair and skin abnormalities and increases the production of lecithin in the liver by lowering the blood cholesterol level. It also controls ammonia formation and affects hair follicles, preventing hair growth and hair loss, removing toxic wastes from the liver, preventing fatigue, and containing a lot of meat, fish, eggs, milk, and tofu.
Tryptophan is a natural relaxant that induces normal sleep, inhibits stress and nervousness, is effective in the treatment of migraine, is involved in immune enhancement, reduces the risk of seizures in arteries and heart, and increases cholesterol levels And is effective for dementia, and is involved in promotion of brain nerve development and promotion of physical growth. It is commonly found in milk, peanuts, fish, meat and bananas.
The lysine is associated with fatigue recovery, concentration, anemia and dizziness,
Helps to form collagen, helps produce antibodies, hormones, enzymes, improves nutrient balance to reduce viral growth, and is effective in bone, cartilage formation, antibody enhancement, and secretion of digestive juices. It is generally contained in milk, cheese, and eggs.
The above-mentioned histidine accelerates lipolysis, prevents skin damage from ultraviolet rays, solves insensitivity and increases sexual desire, helps to treat rheumatoid arthritis, increases gastric acid gastric juice, helps digestion, Pregnancy, after ovulation, can speed up the menstrual date, is essential for the growth of the children, and is abundant in fish, meat, eggs, dairy cereals and protein foods.
Non-essential amino acids are amino acids that can be synthesized from the intermediate metabolites of carbohydrates and nitrogen or essential amino acids in the body. The most important amino acid of crickets is arginine amino acid.
remind When arginine enters the body, it turns into nitric oxide, increases vasodilation and blood flow, and is effective in the treatment of erectile dysfunction in men, such as improving sexual function, promoting sperm production, and improving immunity and physical strength. Therefore, it is called as a health booster during weight training.
Prior art documents relating to such cricket-related food compositions include Korea Patent No. 10-0453575, which discloses a food composition containing crickets or their extracts for liver protection, restoring fatigue of the tongue, promoting alcohol metabolism, and inhibiting lipid peroxidation Korean Patent Laid-Open No. 10-2013-0134097 discloses a composition for preventing or treating skin inflammation containing a cricket extract, but does not disclose a technology relating to a food composition related to the anticancer effect.
Disclosure of the Invention The present invention was developed to solve the problems of the prior art as described above, and it is an object of the present invention to provide a method for manufacturing a food composition using the cricket so as to increase the content of the active ingredient, The present invention also provides a cricket with improved anticancer effect that significantly enhances the anti-cancer effect and a food composition containing the cricket.
In order to attain the above object, the present invention relates to a method for producing rice bran, which comprises mixing 14 to 16 parts by weight of tomato, 14 to 16 parts by weight of garlic, 14 to 16 parts by weight of garlic, 14 to 16 parts by weight of amber, The feedstuffs containing 14 to 16 parts by weight of sweet potatoes and 14 to 16 parts by weight of cheonggukjang were fed to crickets three times a day and fed 0.005 to 0.02 g / The present invention relates to a method of raising crickets that have enhanced anticancer effects including 1.7 to 2.3% of vitamin B group, 1.2 to 1.5% of vitamin C, 0.25 to 0.35% of vitamin E, 1 to 2% of beta carotene and 0.3 to 0.5% of lycopene, Characterized in that the cricket is promoted to produce a food composition.
The cricket with the improved anticancer effect according to the present invention as described above is fed with feed containing rice bran, tomato, garlic, cucumber, zucchini, spinach, sweet potato and chongkukjang so that the content of active ingredient involved in anti- It is possible to remarkably enhance the anticancer effect compared with general crickets.
As a result, the food composition containing the cricket, in which the anticancer effect is enhanced, has the effect of significantly improving the anticancer effect.
In addition, by feeding the main ingredients of cricket feed to rice bran, it is possible to recycle the by-product of the farmhouse, and it is possible to prevent natural natural circulation and feed import of livestock and insects.
Hereinafter, preferred embodiments of the present invention will be described in detail. These examples are for further illustrating the present invention, and the scope of rights of the present invention is not limited to these examples.
The cricket improved in anticancer effect according to the present invention comprises 14 to 16 parts by weight of tomato, 14 to 16 parts by weight of garlic, 14 to 16 parts by weight of garlic, 14 to 16 parts by weight of squash, 14 to 16 parts by weight of spinach, 14 to 16 parts by weight of sweet potato, and 14 to 16 parts by weight of chungkukjang. That is, the feed is to supply tomatoes, garlic, cucumber, pumpkin, spinach, sweet potato, and chungkukjang as raw materials having rice bran as a main ingredient and having a specific substrate. At this time, the main material and the sub material may be mixed at a weight ratio of 1: 0.98 to 1.12. If the weight ratio of the sub material is more than 1.12, the materials constituting the sub material having a specific substrate may have strong characteristics and cause side effects. There is a problem that the efficacy of a material having a specific substrate may be lowered.
The rice bran is a crushed mixture of peel, seed and hornblende, which are produced when brown rice is harvested. Most of the rice bran is used for livestock feed at farms, but rice bran contains innumerable nutrients. The standard composition of rice bran contains 13.5% of water, 13.2% of protein, 18.3% of fat, 38.3% of carbohydrate, 7.8% of fiber, inorganic matter It is a nutritional supplement containing 8.9%, vitamin A, vitamin B1, vitamin B6, vitamin E, iron, phosphorus and minerals. This rice bran is the greatest advantage to be able to defend the natural virtuous cycle and feed imports of livestock and insects by recycling farmhouse byproducts by feeding crickets.
About 95% of the tomatoes are moisture, and contain 0.9% protein, 0.1% fat, 2.9% carbohydrates, 0.4% cellulose, 0.5% ash. In particular, tomatoes contain vitamin C to help metabolism and vitamin B to help break down fat, folic acid, biotin, niacin, and other vitamins, as well as minerals such as calcium and iron essential for hematopoiesis. It is rich in natural amino acids, such as glutamic acid, which is not easily seen in other vegetables. It also contains a large amount of beta-carotene, which is a precursor of vitamin A and has antioxidant and anti-cancer effects. The nutrients contained in one tomato (200 g) contain citric acid, malic acid, succinic acid, amino acid, rutin, protein, saccharide, ash, calcium, iron, phosphorus, vitamin A, B1, B2, Lycopene, beta carotene, and many other antioxidants, which are found to be particularly effective for prostate cancer. These ingredients can produce highly functional crickets with specific substrates that act on cancer when administered to crickets.
The garlic is excellent in anticancer and nutrition, and contains a physiologically active scorodin, which warms the organs and increases metabolism and energy. Garlic contains 77% moisture, 20% carbohydrate, 1.3% protein, potassium, sulfur, silicic acid, chlorine, soda, phosphorus and other vitamins A, B, C and E, Germanium, which contains 754 ppm of ginger, is also known as the best anti-cancer food. By feeding the garlic to crickets, it is possible to produce high-function crickets that have the necessary ingredients for anti-cancer and have a 30% improvement over the original crickets.
The above-mentioned cucurbitan has been used for many years as an agricultural medicinal product for a long time. The cucumber has abundant vitamins B1, B2 and C, a high calcium and mineral content, and a physiologically active substance such as flavonoid, gabaproate, aspartic acid, glutamic acid, It is also famous for its abundant and excellent anticancer effect. Culjipon is famous for its 4 kinds of anticancer foods. It is especially effective for stomach cancer, lung cancer, liver cancer, esophageal cancer and uterine cancer. Therefore, when such crickets are fed to crickets, they can produce crickets that can increase the anti-cancer function by more than 30% have.
Like the carrots, the amber is abundant in natural carotenoid components such as excreted carotene and alpha-carotene, and thus has excellent antioxidative effects against cancer. Beta-carotene, which is converted to vitamin A, is known to be an antioxidant that eliminates active oxygen that damages cell membranes and genes, promotes the expression of cancer-suppressing genes, and inhibits phospholipid metabolism involved in cell mutagenesis. The pumpkin contains a lot of alpha carotene. According to the results of a rat experiment conducted by Professor Nishino of Japan, the substance is several times more resistant to lung cancer, liver cancer and skin cancer than beta carotene.
The spinach actually contains 4200 g per 100 g of carotenoid (beta-carotene) ingredient, which is an excellent antioxidant effective vitamin A supplement. Spinach has recently been attracting attention due to its rich lutein content, and Lutein is also an antioxidant that has the effect of inhibiting skin cancer and colorectal cancer by its strong active oxygen scavenging effect. Spinach contains vitamin A, vitamin B, vitamin C, and vitamin D in an even distribution. In 100 g of spinach, 0.12 mg of vitamin B1, 0.3 mg of vitamin B2 and 1 mg of vitamin B3 are contained. The recommended daily amount of vitamin A is 5,000 IU. The physiological substance called vitamin A is produced starting from a component called β-carotene, which is an anticancer substance.
The sweet potato is used as a food for the constipation and winter diet, which has better anti-cancer effect than any mushroom or weakness. Dr. Yoshio Samaru, a Japanese glass nokki clinic, conducted an experiment to evaluate the anticancer effect of 82 kinds of vegetables in the Institute of Medical Science, University of Tokyo. As a result, surprisingly, the inhibition rate of cancer cell division and proliferation of sweet potatoes was 98.7% and 94.4%, respectively. Next, asparagus (93.7%), parsley (83.7%), eggplant (74,8%) and celery (73.7%) were the products with high cancer cell division and proliferation inhibition rate. The potent anticancer effect of sweet potatoes has been shown to be due to the inhibition of the growth of cancer cells. Sweet potatoes are effective at preventing colorectal cancer by eating half a day. Sweet potatoes are rich in beta-carotene, vitamin C and glutathione, known as antioxidants, and are well absorbed by the body. Eating one sweet potato daily can consume twice the amount of beta-carotene needed per day. When these sweet potatoes are added to crickets, they can produce crickets that have improved anti - cancer function more than when they are fed ordinary crickets.
The Chungkukjang specifically removes toxins from the body and provides anticancer action. Among cancer, lung cancer, rectal cancer, stomach cancer, prostate cancer and especially can be effective, because it is rich in saponin, pituxine, genistein ingredients such as anticancer action and helps to treat or prevent cancer . When these cheonggukjang are administered together with the injection, highly functional crickets against cancer can be obtained.
The feed composed of these materials may be prepared by mixing the respective ingredients intact or by pulverizing the mixture into 50 to 100 mesh and preparing the mixture in the form of pellets.
The feed is fed to crickets three times a day, 0.005 to 0.02 g per bird per feeding.
The cricket has a temperature of 27 to 32 ° C, a humidity of 60 to 75%, and the light is regulated to 10 hours of light for a day and dark for 14 hours.
The cricket thus raised promotes vitamin A, vitamin B group, vitamin C, vitamin D, vitamin E, beta-carotene and lycopene, which are involved in the anticancer effect. Particularly, 0.015-0.025% 1.7 to 2.3% of vitamin B group, 1.2 to 1.5% of vitamin C, 0.25 to 0.35% of vitamin E, 1 to 2% of beta carotene and 0.3 to 0.5% of lycopene.
As a result, the cricket enhances the anticancer effect and has an excellent effect on the anti-cancer effect.
<
Example
1> Cricket with enhanced anti-cancer effect
The feed composed of 15 parts by weight of tomato, 15 parts by weight of garlic, 15 parts by weight of cucumber, 15 parts by weight of zucchini, 15 parts by weight of spinach, 15 parts by weight of sweet potato and 15 parts by weight of chungkukjang was added to crickets three times per day The crickets were fed at a temperature of 30 ° C, a humidity of 60%, light for 10 hours, and dark for 14 hours, for 30 days.
The crickets raised in the above can be used as food only by the cricket itself, and the crickets can be manufactured in various forms such as powder, capsule, ring, and extract.
<
Test Example
1> Nutritional analysis of cricket with enhanced anti-cancer effect
The nutritional components of crickets and general crickets raised in the above Example 1 were compared.
(Table 1) Nutritional composition of cricket
As shown in Table 1, the crickets enhanced with anti-cancer effect were significantly higher in vitamin A, vitamin B group, vitamin C group, and vitamin C group than those of general crickets by feeding feeds composed of rice bran, tomato, garlic, cucumber, amber, spinach, sweet potato, , Vitamin D, Vitamin E, Beta Carotene and Lycopene were increased. Especially, vitamin A 0.015 ~ 0.025%, vitamin B 1.7 ~ 2.3%, vitamin C 1.2 ~ 1.5% and vitamin E 0.25 ~ 0.35%, beta carotene 1-2%, lycopene 0.3-0.5%. As a result, it can be seen that crickets promoted by the anticancer effect can enhance the anti-cancer effect.
<
Example
2> Production of cricket extract with enhanced anti-cancer effect
500 g of the cricket with the enhanced anticancer effect was subjected to hot-water extraction in 5,000 to 6,000 ml of distilled water, the obtained hot-water extract solution was concentrated at a ratio of 1/50 to 1/60, and then lyophilized to obtain an effective concentration of 250 to 350 mg / Kg. If the effective concentration exceeds 350 mg / kg, the effect of increasing the anticancer activity may be insignificant and the effect of increasing the anticancer activity may be lowered when the effective concentration is less than 250 mg / kg.
In Example 2, 500 g of the cricket with the enhanced anticancer effect was subjected to hot-water extraction in 5,000 ml of distilled water, the obtained hot-water extract was concentrated at a ratio of 1/50, and then lyophilized to obtain an effective concentration of 300 mg / kg do.
Hereinafter, a test for estimating the anticancer effect and appropriate effective concentration of the cricket extract with the enhanced anticancer effect will be described.
<
Test Example
2> Increased anti-cancer effect of cricket extract
In
vitro
Antitumor effect test (MTT
assay
)
The anti-cancer effect of the cricket extract prepared in Example 2 was investigated in various cancer cell lines. The cytotoxic effect of the samples on cancer cells was evaluated by MTT colorimetric assay.
First, the medium was removed from the cultured cells, PBS was added, and the mixture was lightly mixed. PBS was again removed, and a trypsin / EDTA solution was added thereto. The mixture was incubated at 37 ° C for 5 minutes, ), The cells were observed under a microscope. Then, the culture medium was added, and the cells were mixed and adjusted to 1 x 104 cells / ml. Samples were dissolved in PBS and filtered through a 0.22 ㎛ membrane filter. The prepared cells were inoculated into a 96-well microtiter plate at a concentration of 104 cells / well. After the sample was treated, the cells were cultured in a 5% CO2 incubator for 2 days. 50 占 퐇 of MTT reagent was added to each well, and MTT was further cultured for 4 hours so as to be reduced by the enzymatic action of surviving cancer cells. The supernatant was carefully removed (for Jurkat cells, the supernatant was removed), and 200 μl of DMSO and 25 μl of Soerensen's buffer were added to the lower layer to dissolve the formazan crystals. The microplate reader The absorbance was measured with a microplate reader. This absorbance represents the amount of MTT reduced by the cells and is therefore proportional to the number of survivors present in each well. The average value of one column was obtained from each well, and a percentage of the average value of the control group (survival group of 100%) was calculated. This percentage corresponds to the cell viability of the test group to be compared, and the cell viability was calculated by the following equation.
Cell survival rate (%) = [T (OD of treated cell) / C (OD of control cell)] x 100
All experiments were performed three times and averaged. The target cancer cells are SNU778 (cervical cancer), SNU719 (stomach cancer), Hep3B (liver cancer), A253 (oral cancer) and Jurkat-T (blood cancer), the treatment of cricket extract 200, 300, 400, and 500 mg / kg, respectively. The measurement results are shown in Tables 1 to 5 below.
(Table 1) SNU778 (cervical cancer)
(Table 2) SNU719 (stomach cancer)
(Table 3) Hep3B (liver cancer)
(Table 4) A253 (oral cancer)
(Table 5) Jurkat-T (blood cancer)
As shown in the above Tables 1 to 5, the cricket extracts having enhanced anticancer effect were classified into 5 groups such as SNU778 (cervical cancer), SNU719 (stomach cancer), Hep3B (liver cancer), A253 (oral cancer), Jurkat- And showed excellent anticancer effect against the cancer cell, especially hepatocarcinoma. Based on the above results, IC 50 , which is a concentration that inhibits 50% of cancer cells, is calculated, and the results are shown in Table 6 below.
(Table 6) IC 50 of cricket extracts enhanced by anti-cancer effect according to cancer cell type
As shown in Table 6, the optimal concentration of the cricket extract promoted the anti-cancer effect to exhibit inhibitory activity against various cancer cells is 250 to 350 mg / kg.
<
Example
3> Preparation of a food composition containing cricket with enhanced anti-cancer effect
The food composition is prepared by containing the extract prepared in Example 2, wherein the food composition refers to a food that people consume on a daily basis, and is a collective name for eating and drinking by a person. Therefore, the form of the food composition in the present invention is not particularly limited, but may be made into a drink form for convenience of drinking.
In the case of preparing in the form of a drink, for example, 10 to 50 parts by weight of fruit extract, 0.1 to 5 parts by weight of taurine, 0.1 to 5 parts by weight of citric acid, 10 to 20 parts by weight of carbohydrate and 0.1 to 10 parts by weight of the above- . ≪ / RTI >
The carbohydrate may be composed of at least one of glucose, fructose, maltose, sucrose, dextrin, and cyclodextrin.
Example 3 is prepared by mixing 30 parts by weight of fruit extract, 3 parts by weight of taurine, 3 parts by weight of citric acid, 10 parts by weight of glucose and 5 parts by weight of the extract, based on 100 parts by weight of purified water.
Claims (4)
The feed,
The crickets are fed three times per day to crickets, which are fed with 0.005 to 0.02 g per bird per feeding.
The cricket includes:
The anticancer effect promoted cricket containing 0.015 ~ 0.025% of vitamin A, 1.7 ~ 2.3% of vitamin B group, 1.2 ~ 1.5% of vitamin C, 0.25 ~ 0.35% of vitamin E, 1-2% of beta carotene and 0.3 ~ 0.5% .
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190033814A (en) * | 2017-09-22 | 2019-04-01 | 농업회사법인 주식회사 귀뜰 | Feed composition for cricker comprising sweet pumpkin and manufacturing method thereof |
| KR102212276B1 (en) * | 2019-08-01 | 2021-02-05 | 공주대학교 산학협력단 | Compositions for treating non-small cell lung cancer, including extracts of Gryllus bimaculatus |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100453575B1 (en) | 2001-07-09 | 2004-10-20 | 대한민국 | Food compositons derived from or containing crickets, exerting hepato-protective, antifatigue, enhancing activity of ethanol degradation, and inhibiting the formation of lipid-peroxidation |
| KR20130134097A (en) | 2012-05-30 | 2013-12-10 | 경북대학교 산학협력단 | Preventive and therapeutic compositions for skin inflammation comprising cricket extracts |
-
2015
- 2015-02-05 KR KR1020150017734A patent/KR20160096295A/en not_active Application Discontinuation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100453575B1 (en) | 2001-07-09 | 2004-10-20 | 대한민국 | Food compositons derived from or containing crickets, exerting hepato-protective, antifatigue, enhancing activity of ethanol degradation, and inhibiting the formation of lipid-peroxidation |
| KR20130134097A (en) | 2012-05-30 | 2013-12-10 | 경북대학교 산학협력단 | Preventive and therapeutic compositions for skin inflammation comprising cricket extracts |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190033814A (en) * | 2017-09-22 | 2019-04-01 | 농업회사법인 주식회사 귀뜰 | Feed composition for cricker comprising sweet pumpkin and manufacturing method thereof |
| KR102212276B1 (en) * | 2019-08-01 | 2021-02-05 | 공주대학교 산학협력단 | Compositions for treating non-small cell lung cancer, including extracts of Gryllus bimaculatus |
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