KR20160072258A - 감지를 위한 방법 및 시스템 - Google Patents

감지를 위한 방법 및 시스템 Download PDF

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KR20160072258A
KR20160072258A KR1020167013559A KR20167013559A KR20160072258A KR 20160072258 A KR20160072258 A KR 20160072258A KR 1020167013559 A KR1020167013559 A KR 1020167013559A KR 20167013559 A KR20167013559 A KR 20167013559A KR 20160072258 A KR20160072258 A KR 20160072258A
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South Korea
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sensing
sample
cells
chamber
nanostructure
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Korean (ko)
Inventor
페르난도 파톨스키
리-창 시웅
바딤 크리비츠키
블라디미르 나다카
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라모트 앳 텔-아비브 유니버시티 리미티드
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Publication of KR20160072258A publication Critical patent/KR20160072258A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3278—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction involving nanosized elements, e.g. nanogaps or nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4146—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS involving nanosized elements, e.g. nanotubes, nanowires
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7057—(Intracellular) signaling and trafficking pathways
    • G01N2800/7066—Metabolic pathways

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Electrochemistry (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
KR1020167013559A 2013-10-22 2014-10-22 감지를 위한 방법 및 시스템 Ceased KR20160072258A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361893977P 2013-10-22 2013-10-22
US61/893,977 2013-10-22
PCT/IL2014/050921 WO2015059704A1 (en) 2013-10-22 2014-10-22 Method and system for sensing

Publications (1)

Publication Number Publication Date
KR20160072258A true KR20160072258A (ko) 2016-06-22

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KR1020167013559A Ceased KR20160072258A (ko) 2013-10-22 2014-10-22 감지를 위한 방법 및 시스템

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US (2) US10274456B2 (cg-RX-API-DMAC7.html)
EP (1) EP3060675B1 (cg-RX-API-DMAC7.html)
JP (1) JP6609247B2 (cg-RX-API-DMAC7.html)
KR (1) KR20160072258A (cg-RX-API-DMAC7.html)
CN (1) CN106164286A (cg-RX-API-DMAC7.html)
AU (1) AU2014338510A1 (cg-RX-API-DMAC7.html)
CA (1) CA2927332A1 (cg-RX-API-DMAC7.html)
HK (1) HK1225414B (cg-RX-API-DMAC7.html)
MX (1) MX2016005273A (cg-RX-API-DMAC7.html)
SG (1) SG11201602976XA (cg-RX-API-DMAC7.html)
WO (1) WO2015059704A1 (cg-RX-API-DMAC7.html)

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EP3060675B1 (en) 2013-10-22 2019-01-30 Ramot at Tel-Aviv University Ltd. Method and system for sensing
JP6823589B2 (ja) * 2014-09-11 2021-02-03 キュー ヘルス インコーポレイテッド 被分析物の検出および定量のためのシステム
WO2017098518A1 (en) * 2015-12-09 2017-06-15 Ramot At Tel-Aviv University Ltd. Method and system for sensing
AU2017239168B2 (en) * 2016-03-21 2022-02-03 University Of South Australia Oxidant sensor
KR102357587B1 (ko) * 2016-06-10 2022-02-07 유니레버 글로벌 아이피 리미티드 기계 내에 도입되는 유체 배합물의 품질을 검출함으로써 기계 또는 공정을 제어하기 위한 장치를 포함하는 기계, 및 상응하는 방법
EP3500168B1 (en) * 2016-08-22 2021-06-23 Ramot at Tel-Aviv University Ltd. System for subcutaneous bioanalyte sensing
JP2019526794A (ja) * 2016-08-22 2019-09-19 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッドＲａｍｏｔ Ａｔ Ｔｅｌ Ａｖｉｖ Ｕｎｉｖｅｒｓｉｔｙ Ｌｔｄ． 生物検体の検出のための方法およびシステム
US11193888B2 (en) 2017-03-29 2021-12-07 Ramot At Tel-Aviv University Ltd. Method and system for separating biomolecules from a mixture containing same
WO2018198008A1 (en) * 2017-04-24 2018-11-01 Abdolahad Mohammad In-situ microbubbles generation for ultrasonic biomedical applications
US10422780B2 (en) 2017-06-15 2019-09-24 Ramot At Tel-Aviv University Ltd. Electrochemical detection of peroxide-containing compounds
WO2018229780A1 (en) 2017-06-15 2018-12-20 Ramot At Tel-Aviv University Ltd. Electrochemical detection of nitro-containing compounds
EP3638112A4 (en) * 2017-06-20 2021-03-31 Abdolahad, Mohammad REAL-TIME, MARKERLESS ANALYZER FOR IN VITRO AND IN VIVO DETECTION OF AREAS SUSPECTED IN CANCER
US10786188B1 (en) * 2017-06-20 2020-09-29 Mohammad Abdolahad Real-time and label free analyzer for in-vitro and in-vivo detection of cancer
US11179077B2 (en) 2017-06-20 2021-11-23 Mohammad Abdolahad Apparatus for in-vivo measuring of H2O2 oxidation
CN111051871B (zh) * 2017-08-01 2022-05-10 伊鲁米纳公司 场效应传感器
US11619634B2 (en) * 2017-08-21 2023-04-04 Savicell Diagnostic Ltd. Methods of diagnosing and treating lung cancer
TWI765209B (zh) * 2019-01-18 2022-05-21 國立陽明交通大學 用來偵測全細胞細菌之以場效電晶體為主的生物感測器以及包含生物感測器的生物感測器組
JP7455187B2 (ja) 2019-07-12 2024-03-25 キューラブ・メディカル・リミテッド 電気化学ｆｅｔセンサ
CN111487107B (zh) * 2020-06-07 2022-12-09 黑龙江省农业科学院农产品质量安全研究所 一种用于食品安全检测的样本分级处理装置
TWI852718B (zh) * 2023-08-08 2024-08-11 國立清華大學 多病毒檢測裝置、系統及其使用方法

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US20190234900A1 (en) 2019-08-01
AU2014338510A1 (en) 2016-06-09
JP6609247B2 (ja) 2019-11-20
HK1225414B (en) 2017-09-08
SG11201602976XA (en) 2016-05-30
WO2015059704A1 (en) 2015-04-30
CN106164286A (zh) 2016-11-23
US10274456B2 (en) 2019-04-30
CA2927332A1 (en) 2015-04-30
EP3060675A1 (en) 2016-08-31
MX2016005273A (es) 2017-01-05
JP2016535988A (ja) 2016-11-24
EP3060675B1 (en) 2019-01-30
US20160258899A1 (en) 2016-09-08

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