JP6609247B2 - 検知のための方法及びシステム - Google Patents
検知のための方法及びシステム Download PDFInfo
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- JP6609247B2 JP6609247B2 JP2016525073A JP2016525073A JP6609247B2 JP 6609247 B2 JP6609247 B2 JP 6609247B2 JP 2016525073 A JP2016525073 A JP 2016525073A JP 2016525073 A JP2016525073 A JP 2016525073A JP 6609247 B2 JP6609247 B2 JP 6609247B2
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/004—Enzyme electrodes mediator-assisted
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- G—PHYSICS
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- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/403—Cells and electrode assemblies
- G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
- G01N27/4146—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS involving nanosized elements, e.g. nanotubes, nanowires
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
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- G—PHYSICS
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- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
- G01N27/3278—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction involving nanosized elements, e.g. nanogaps or nanoparticles
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7057—(Intracellular) signaling and trafficking pathways
- G01N2800/7066—Metabolic pathways
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Urology & Nephrology (AREA)
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- Nanotechnology (AREA)
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| US61/893,977 | 2013-10-22 | ||
| PCT/IL2014/050921 WO2015059704A1 (en) | 2013-10-22 | 2014-10-22 | Method and system for sensing |
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| EP3060675B1 (en) | 2013-10-22 | 2019-01-30 | Ramot at Tel-Aviv University Ltd. | Method and system for sensing |
| JP6823589B2 (ja) * | 2014-09-11 | 2021-02-03 | キュー ヘルス インコーポレイテッド | 被分析物の検出および定量のためのシステム |
| WO2017098518A1 (en) * | 2015-12-09 | 2017-06-15 | Ramot At Tel-Aviv University Ltd. | Method and system for sensing |
| AU2017239168B2 (en) * | 2016-03-21 | 2022-02-03 | University Of South Australia | Oxidant sensor |
| KR102357587B1 (ko) * | 2016-06-10 | 2022-02-07 | 유니레버 글로벌 아이피 리미티드 | 기계 내에 도입되는 유체 배합물의 품질을 검출함으로써 기계 또는 공정을 제어하기 위한 장치를 포함하는 기계, 및 상응하는 방법 |
| EP3500168B1 (en) * | 2016-08-22 | 2021-06-23 | Ramot at Tel-Aviv University Ltd. | System for subcutaneous bioanalyte sensing |
| JP2019526794A (ja) * | 2016-08-22 | 2019-09-19 | ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッドＲａｍｏｔ Ａｔ Ｔｅｌ Ａｖｉｖ Ｕｎｉｖｅｒｓｉｔｙ Ｌｔｄ． | 生物検体の検出のための方法およびシステム |
| US11193888B2 (en) | 2017-03-29 | 2021-12-07 | Ramot At Tel-Aviv University Ltd. | Method and system for separating biomolecules from a mixture containing same |
| WO2018198008A1 (en) * | 2017-04-24 | 2018-11-01 | Abdolahad Mohammad | In-situ microbubbles generation for ultrasonic biomedical applications |
| US10422780B2 (en) | 2017-06-15 | 2019-09-24 | Ramot At Tel-Aviv University Ltd. | Electrochemical detection of peroxide-containing compounds |
| WO2018229780A1 (en) | 2017-06-15 | 2018-12-20 | Ramot At Tel-Aviv University Ltd. | Electrochemical detection of nitro-containing compounds |
| EP3638112A4 (en) * | 2017-06-20 | 2021-03-31 | Abdolahad, Mohammad | REAL-TIME, MARKERLESS ANALYZER FOR IN VITRO AND IN VIVO DETECTION OF AREAS SUSPECTED IN CANCER |
| US10786188B1 (en) * | 2017-06-20 | 2020-09-29 | Mohammad Abdolahad | Real-time and label free analyzer for in-vitro and in-vivo detection of cancer |
| US11179077B2 (en) | 2017-06-20 | 2021-11-23 | Mohammad Abdolahad | Apparatus for in-vivo measuring of H2O2 oxidation |
| CN111051871B (zh) * | 2017-08-01 | 2022-05-10 | 伊鲁米纳公司 | 场效应传感器 |
| US11619634B2 (en) * | 2017-08-21 | 2023-04-04 | Savicell Diagnostic Ltd. | Methods of diagnosing and treating lung cancer |
| TWI765209B (zh) * | 2019-01-18 | 2022-05-21 | 國立陽明交通大學 | 用來偵測全細胞細菌之以場效電晶體為主的生物感測器以及包含生物感測器的生物感測器組 |
| JP7455187B2 (ja) | 2019-07-12 | 2024-03-25 | キューラブ・メディカル・リミテッド | 電気化学ｆｅｔセンサ |
| CN111487107B (zh) * | 2020-06-07 | 2022-12-09 | 黑龙江省农业科学院农产品质量安全研究所 | 一种用于食品安全检测的样本分级处理装置 |
| TWI852718B (zh) * | 2023-08-08 | 2024-08-11 | 國立清華大學 | 多病毒檢測裝置、系統及其使用方法 |
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| DE2214442C3 (de) * | 1972-03-24 | 1981-09-10 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur Überführung von Glucose in Gluconsäure |
| WO2002048701A2 (en) | 2000-12-11 | 2002-06-20 | President And Fellows Of Harvard College | Nanosensors |
| AU2003282548A1 (en) | 2002-10-10 | 2004-05-04 | Nanosys, Inc. | Nano-chem-fet based biosensors |
| US7416911B2 (en) | 2003-06-24 | 2008-08-26 | California Institute Of Technology | Electrochemical method for attaching molecular and biomolecular structures to semiconductor microstructures and nanostructures |
| EP2013611A2 (en) * | 2006-03-15 | 2009-01-14 | The President and Fellows of Harvard College | Nanobioelectronics |
| WO2008030395A1 (en) * | 2006-09-07 | 2008-03-13 | California Institute Of Technology | Apparatus and method for quantitative determination of target molecules |
| US20100093019A1 (en) * | 2007-01-12 | 2010-04-15 | Environmental Biotechnology Crc Pty Limited | Sample handling device |
| IL189576A0 (en) | 2008-02-18 | 2008-12-29 | Technion Res & Dev Foundation | Chemically sensitive field effect transistors for explosive detection |
| EP2364382A2 (en) | 2008-11-04 | 2011-09-14 | Ramot at Tel-Aviv University Ltd. | Tubular nanostructures, processes of preparing same and devices made therefrom |
| EP2373996A2 (en) | 2008-12-05 | 2011-10-12 | Nanoivd, Inc. | Microfluidic-based lab-on-a-test card for a point-of-care analyzer |
| WO2010115143A1 (en) | 2009-04-03 | 2010-10-07 | University Of Southern California | Surface modification of nanosensor platforms to increase sensitivity and reproducibility |
| GB2471470A (en) | 2009-06-30 | 2011-01-05 | Hewlett Packard Development Co | Quantum repeater and system and method for creating extended entanglements utilising cyclic synchronised control signals at repeater relay nodes |
| DE102010002915B4 (de) * | 2010-03-16 | 2012-10-18 | Senslab-Gesellschaft Zur Entwicklung Und Herstellung Bioelektrochemischer Sensoren Mbh | Mikrofluidischer Sensor |
| JP2014505239A (ja) * | 2010-12-14 | 2014-02-27 | モアハウス スクール オブ メディスン | 癌の治療または検出のための抗ｃｘｃｌ１３および抗ｃｘｃｒ５抗体の使用 |
| CN103518133B (zh) | 2011-04-06 | 2016-08-17 | 雷蒙特亚特特拉维夫大学有限公司 | 监测和分析代谢活性分布的方法及其诊断和治疗用途 |
| EP3060675B1 (en) | 2013-10-22 | 2019-01-30 | Ramot at Tel-Aviv University Ltd. | Method and system for sensing |
| WO2017098518A1 (en) | 2015-12-09 | 2017-06-15 | Ramot At Tel-Aviv University Ltd. | Method and system for sensing |
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| US10274456B2 (en) | 2019-04-30 |
| CA2927332A1 (en) | 2015-04-30 |
| EP3060675A1 (en) | 2016-08-31 |
| MX2016005273A (es) | 2017-01-05 |
| JP2016535988A (ja) | 2016-11-24 |
| EP3060675B1 (en) | 2019-01-30 |
| US20160258899A1 (en) | 2016-09-08 |
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