KR20150141971A - 이브루티닙 병용 요법 - Google Patents

이브루티닙 병용 요법 Download PDF

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KR20150141971A
KR20150141971A KR1020157029969A KR20157029969A KR20150141971A KR 20150141971 A KR20150141971 A KR 20150141971A KR 1020157029969 A KR1020157029969 A KR 1020157029969A KR 20157029969 A KR20157029969 A KR 20157029969A KR 20150141971 A KR20150141971 A KR 20150141971A
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South Korea
Prior art keywords
ibrutinib
anticancer agent
agent
cancer
lymphoma
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KR1020157029969A
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Korean (ko)
Inventor
브렛 홀
에이. 케이트 새서
마이클 샤퍼
쿡 데이비스
티네크 카스누프
마티아스 베르셀레
윌렘 리그텐베르그
베티 창
스리람 발라서브라마니안
리차드 크로울리
수-핑 쿠오
Original Assignee
파마싸이클릭스 엘엘씨
잔센파마슈티카엔.브이.
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Publication of KR20150141971A publication Critical patent/KR20150141971A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • AHUMAN NECESSITIES
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    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
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    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/53751,4-Oxazines, e.g. morpholine
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    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K31/66Phosphorus compounds
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    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
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    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020157029969A 2013-04-08 2014-04-08 이브루티닙 병용 요법 Ceased KR20150141971A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361809810P 2013-04-08 2013-04-08
US61/809,810 2013-04-08
PCT/US2014/033378 WO2014168975A1 (en) 2013-04-08 2014-04-08 Ibrutinib combination therapy

Publications (1)

Publication Number Publication Date
KR20150141971A true KR20150141971A (ko) 2015-12-21

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ID=51689963

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157029969A Ceased KR20150141971A (ko) 2013-04-08 2014-04-08 이브루티닙 병용 요법

Country Status (14)

Country Link
US (2) US20160287592A1 (https=)
EP (1) EP2983670A4 (https=)
JP (3) JP6575952B2 (https=)
KR (1) KR20150141971A (https=)
CN (2) CN111317821A (https=)
AU (3) AU2014251028A1 (https=)
BR (1) BR112015025711A8 (https=)
CA (1) CA2908375A1 (https=)
EA (1) EA201591656A1 (https=)
HK (1) HK1215374A1 (https=)
IL (2) IL241710B (https=)
MX (2) MX369503B (https=)
PH (2) PH12015502337A1 (https=)
WO (1) WO2014168975A1 (https=)

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KR20180013817A (ko) * 2016-07-29 2018-02-07 이화여자대학교 산학협력단 크로메논 유도체 및 이를 포함하는 항암용 조성물

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