KR20150139830A - 신경변성 및 기타 질환의 치료를 위한 조성물 및 방법 - Google Patents

신경변성 및 기타 질환의 치료를 위한 조성물 및 방법 Download PDF

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Publication number
KR20150139830A
KR20150139830A KR1020157023718A KR20157023718A KR20150139830A KR 20150139830 A KR20150139830 A KR 20150139830A KR 1020157023718 A KR1020157023718 A KR 1020157023718A KR 20157023718 A KR20157023718 A KR 20157023718A KR 20150139830 A KR20150139830 A KR 20150139830A
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KR
South Korea
Prior art keywords
sulfasalazine
pharmaceutical composition
patient
pharmaceutically acceptable
measured
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020157023718A
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English (en)
Korean (ko)
Inventor
타데우스 크롬웰 리더
마크 웨이드 무어
더글라스 앨런 로렌츠
데이비드 키스 라이언
Original Assignee
글리아로직스 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 글리아로직스 인코포레이티드 filed Critical 글리아로직스 인코포레이티드
Publication of KR20150139830A publication Critical patent/KR20150139830A/ko
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020157023718A 2013-02-01 2014-01-31 신경변성 및 기타 질환의 치료를 위한 조성물 및 방법 Withdrawn KR20150139830A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361759933P 2013-02-01 2013-02-01
US61/759,933 2013-02-01
US201361780340P 2013-03-13 2013-03-13
US61/780,340 2013-03-13
PCT/US2014/014290 WO2014121137A2 (en) 2013-02-01 2014-01-31 Compositions and methods for the treatment of neurodegenerative and other diseases

Publications (1)

Publication Number Publication Date
KR20150139830A true KR20150139830A (ko) 2015-12-14

Family

ID=50382538

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157023718A Withdrawn KR20150139830A (ko) 2013-02-01 2014-01-31 신경변성 및 기타 질환의 치료를 위한 조성물 및 방법

Country Status (10)

Country Link
US (5) US9597339B2 (https=)
EP (1) EP2950797B1 (https=)
JP (2) JP6328146B2 (https=)
KR (1) KR20150139830A (https=)
CN (1) CN105163735B (https=)
AU (2) AU2014212109B2 (https=)
CA (1) CA2899032A1 (https=)
ES (1) ES2752021T3 (https=)
IL (1) IL240206A0 (https=)
WO (1) WO2014121137A2 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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AU2014212109B2 (en) * 2013-02-01 2018-05-31 Glialogix, Inc. Compositions and methods for the treatment of neurodegenerative and other diseases
KR102364840B1 (ko) 2014-11-05 2022-02-18 삼성전자주식회사 신경세포의 탈수초화와 연관된 질환을 치료하기 위한 약학적 조성물 및 그를 이용하는 방법
US20160199393A1 (en) * 2015-01-08 2016-07-14 China Medical University Methods of treating brain ischemia or hypoxia
ES2650175B1 (es) * 2016-04-15 2019-02-04 Servicio Andaluz De Salud Tratamiento de enfermedades neurodegenerativas
AU2017257603A1 (en) * 2016-04-26 2018-11-22 Saint Louis University Highly selective adenosine A3 receptor subtype agonsists for the prevention and treatment of neurodegenerative disorders
TW201818933A (zh) 2016-10-21 2018-06-01 美商吉利亞洛吉克斯公司 用於神經退化性及其他疾病的治療之組成物和方法
US10473672B2 (en) * 2017-02-09 2019-11-12 Kaohsiung Chang Gung Memorial Hospital Methods for diagnosing and treating Alzheimers disease using G72 protein and SLC7A11 mRNA as biomarkers
US20230210871A1 (en) * 2017-10-12 2023-07-06 The Limited Company Research And Development Company "Medbiopharm" Use of sulfasalazine as an inhibitor of the formation of advanced glycation end products
WO2019102992A1 (ja) * 2017-11-21 2019-05-31 積水化学工業株式会社 皮膚外用剤

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FR2608988B1 (fr) 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules
PL319600A1 (en) 1994-09-29 1997-08-18 Andaris Ltd Spray-dried microparticles as therapeutic carriers
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
ITMI962356A1 (it) 1996-11-13 1998-05-13 Uni Degli Studi Di Brescia D I Uso di composti derivati da molecole ad attivita' antinfiammatoria di tipo non steroideo per la prevenzione e il trattamento di
DE69732306T2 (de) 1997-01-16 2006-01-12 Massachusetts Institute Of Technology, Cambridge Zubereitung von partikelhaltigen arzneimitteln zur inhalation
CA2336139C (en) 1998-06-24 2008-10-14 Advanced Inhalation Research, Inc. Large porous particles emitted from an inhaler
AU758351B2 (en) 1998-08-25 2003-03-20 Alkermes, Inc. Stable spray-dried protein formulations
US6586008B1 (en) 1999-08-25 2003-07-01 Advanced Inhalation Research, Inc. Use of simple amino acids to form porous particles during spray drying
KR100417623B1 (ko) * 2000-03-28 2004-02-05 주식회사 뉴로테크 뇌질환 예방 및 치료용 조성물
CA2307278A1 (en) 2000-04-28 2001-10-28 University Of British Columbia Use of n-heterocyclic substituted salicylic acids for inhibition of cellular uptake of cystine
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US20060045865A1 (en) 2004-08-27 2006-03-02 Spherics, Inc. Controlled regional oral delivery
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LT1983984T (lt) 2006-02-02 2018-06-11 Novartis Ag Tuberozinės sklerozės gydymas
GB0602123D0 (en) * 2006-02-02 2006-03-15 Novartis Ag Organic compounds
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Also Published As

Publication number Publication date
US9597339B2 (en) 2017-03-21
CN105163735B (zh) 2018-12-11
JP2018123159A (ja) 2018-08-09
US20190015431A1 (en) 2019-01-17
JP6328146B2 (ja) 2018-05-23
EP2950797A2 (en) 2015-12-09
CN105163735A (zh) 2015-12-16
AU2014212109A1 (en) 2015-08-06
WO2014121137A2 (en) 2014-08-07
US10398713B2 (en) 2019-09-03
JP2016507526A (ja) 2016-03-10
US9918997B2 (en) 2018-03-20
AU2014212109B2 (en) 2018-05-31
US20170079991A1 (en) 2017-03-23
US20170165279A1 (en) 2017-06-15
ES2752021T3 (es) 2020-04-02
AU2018222921A1 (en) 2018-09-20
EP2950797B1 (en) 2019-09-11
IL240206A0 (en) 2015-09-24
US9974798B2 (en) 2018-05-22
WO2014121137A3 (en) 2014-11-27
CA2899032A1 (en) 2014-08-07
US9980978B2 (en) 2018-05-29
US20140221321A1 (en) 2014-08-07
US20170079990A1 (en) 2017-03-23

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Date Code Title Description
PA0105 International application

Patent event date: 20150831

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid