KR20150088243A - 고혈압 및 고칼륨혈증을 치료하기 위한 칼륨-결합제 - Google Patents

고혈압 및 고칼륨혈증을 치료하기 위한 칼륨-결합제 Download PDF

Info

Publication number
KR20150088243A
KR20150088243A KR1020157011692A KR20157011692A KR20150088243A KR 20150088243 A KR20150088243 A KR 20150088243A KR 1020157011692 A KR1020157011692 A KR 1020157011692A KR 20157011692 A KR20157011692 A KR 20157011692A KR 20150088243 A KR20150088243 A KR 20150088243A
Authority
KR
South Korea
Prior art keywords
patient
treatment
binding agent
blood pressure
potassium binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020157011692A
Other languages
English (en)
Korean (ko)
Inventor
게릿 클래어너
랜스 버만
Original Assignee
리립사, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49385427&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20150088243(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 리립사, 인크. filed Critical 리립사, 인크.
Publication of KR20150088243A publication Critical patent/KR20150088243A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/16—Organic material
    • B01J39/18—Macromolecular compounds
    • B01J39/20—Macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
KR1020157011692A 2012-10-08 2013-10-08 고혈압 및 고칼륨혈증을 치료하기 위한 칼륨-결합제 Ceased KR20150088243A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261711184P 2012-10-08 2012-10-08
US61/711,184 2012-10-08

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020217000148A Division KR20210005314A (ko) 2012-10-08 2013-10-08 고혈압 및 고칼륨혈증을 치료하기 위한 칼륨-결합제

Publications (1)

Publication Number Publication Date
KR20150088243A true KR20150088243A (ko) 2015-07-31

Family

ID=49385427

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020217000148A Ceased KR20210005314A (ko) 2012-10-08 2013-10-08 고혈압 및 고칼륨혈증을 치료하기 위한 칼륨-결합제
KR1020157011692A Ceased KR20150088243A (ko) 2012-10-08 2013-10-08 고혈압 및 고칼륨혈증을 치료하기 위한 칼륨-결합제

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1020217000148A Ceased KR20210005314A (ko) 2012-10-08 2013-10-08 고혈압 및 고칼륨혈증을 치료하기 위한 칼륨-결합제

Country Status (10)

Country Link
US (6) US10813946B2 (enExample)
EP (1) EP2916851B1 (enExample)
JP (4) JP6475624B2 (enExample)
KR (2) KR20210005314A (enExample)
CN (2) CN104822383A (enExample)
AU (3) AU2013329451B2 (enExample)
BR (1) BR112015007749A2 (enExample)
CA (1) CA2886788C (enExample)
HK (1) HK1210705A1 (enExample)
WO (1) WO2014058905A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220133345A (ko) 2021-03-24 2022-10-05 강원대학교산학협력단 신규한 페디오코커스 악시딜락티시 균주 및 상기 균주를 이용하여 발효시킨 대두 발효물의 다양한 용도

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8337824B2 (en) * 2008-08-22 2012-12-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
EP2916851B1 (en) 2012-10-08 2025-12-17 Vifor (International) Ltd. Potassium-binding agents for treating hypertension and hyperkalemia
KR102633597B1 (ko) 2013-06-05 2024-02-06 트리시다, 인크. 경구 투여를 위한 양성자-결합 중합체
KR20240008418A (ko) 2014-12-10 2024-01-18 트리시다, 인크. 경구 투여용 양성자-결합 폴리머
ITUB20159278A1 (it) * 2015-12-23 2017-06-23 Rjw Pharma Llc Procedimento per la sintesi di patiromer
CN105622602A (zh) * 2016-01-30 2016-06-01 合肥华方医药科技有限公司 一种沙坦类小檗碱偶合物制备方法及其医药用途
AU2017261337A1 (en) 2016-05-06 2018-11-15 Tricida, Inc. Compositions for and method of treating acid-base disorders
US11266684B2 (en) 2017-11-03 2022-03-08 Tricida, Inc. Compositions for and method of treating acid-base disorders
JP7691997B2 (ja) * 2020-03-27 2025-06-12 ヴィフォー （インターナショナル） リミテッド メチル２－フルオロアクリレートの合成
CN111978590B (zh) * 2020-09-04 2021-02-12 四川大学 一种沸石-肝素模拟聚合物共混微球、其制备方法及其应用
US20240139234A1 (en) * 2021-11-17 2024-05-02 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Pharmaceutical polymer for treating hyperkalemia and preparation method thereof

Family Cites Families (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US487958A (en) * 1892-12-13 Patrick mccann
US2340111A (en) 1942-07-03 1944-01-25 Gen Electric Process for removing cations from liquid media
US2611730A (en) 1950-09-02 1952-09-23 Simth Kline & French Lab Medical preparation for reducing the body level of sodium
US2798053A (en) 1952-09-03 1957-07-02 Goodrich Co B F Carboxylic polymers
US2909462A (en) 1955-12-08 1959-10-20 Bristol Myers Co Acrylic acid polymer laxative compositions
US3499960A (en) 1965-01-25 1970-03-10 Merck & Co Inc Palatable coated particles of an anion exchange resin
FR2171934B1 (enExample) 1972-02-16 1974-09-13 Rhone Poulenc Sa
US3974272A (en) 1972-09-01 1976-08-10 Merck & Co., Inc. Palatable cholestyramine coacervate compositions
US4143130A (en) 1977-08-29 1979-03-06 Warren-Teed Laboratories, Inc. Method for treating kidney stones
US4470975A (en) 1977-10-21 1984-09-11 The Johns Hopkins University Method and composition for the elimination of water from an animal body
US4191812A (en) 1978-09-19 1980-03-04 Rohm And Haas Company Ion exchange process involving emulsion ion exchange resins
US4362711A (en) 1980-07-11 1982-12-07 Evreka Inc. Blood cholesterol level reducing agent and method
DE3149136A1 (de) 1981-12-11 1983-06-23 Robert Bosch Gmbh, 7000 Stuttgart Einrichtung zur regelung des kraftstoff-luftverhaeltnisses bei brennkraftmaschinen
JPS6090243A (ja) 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
US5238924A (en) 1984-05-03 1993-08-24 Merck & Co., Inc. Treatment of renal diseases with ace inhibitors
US4747881A (en) 1985-02-05 1988-05-31 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US5186937A (en) 1985-06-07 1993-02-16 A.E.C. Societe De Chimie Organique Et Biologique Composition for feeding ruminants
IT1190349B (it) 1986-06-16 1988-02-16 Prodotti Formenti Srl Composizioni farmaceutiche ad attivita' sequestrante degli acidi biliari contenenti colestiramina quale principio attivo,e procedimento per prepararle
JPS63218713A (ja) 1987-02-17 1988-09-12 Daikin Ind Ltd α−フルオロアクリル酸系重合体ならびに用途
US4837015A (en) 1987-03-05 1989-06-06 Carolina Medical Products Company, Inc. Alkali metal ion-charged, cation exchanger and use thereof to adjust sodium, potassium and calcium body fluid levels
US5210079A (en) 1988-01-07 1993-05-11 E. I. Du Pont De Nemours And Company Treatment of chronic renal failure with imidazole angiotensin-II receptor antagonists
FR2634377B1 (fr) 1988-06-30 1991-09-27 Cortial Nouvelle forme pharmaceutique a liberation prolongee a base d'un complexe resine-principe actif
GB8817015D0 (en) 1988-07-16 1988-08-17 Reckitt & Colmann Prod Ltd Method of treatment
US5236701A (en) 1989-07-19 1993-08-17 Lowchol Scientific Inc. Ingestible hydrophilic polymeric amines useful for lowering blood cholesterol
DE3928990A1 (de) 1989-09-01 1991-03-07 Bayer Ag Verfahren zur herstellung von (alpha)-fluoroacrylsaeurederivaten
US5112993A (en) 1989-11-14 1992-05-12 E. I. Du Pont De Nemours And Company Process for the preparation of difluoromaleic anhydride
US5188825A (en) 1989-12-28 1993-02-23 Iles Martin C Freeze-dried dosage forms and methods for preparing the same
US5091175A (en) 1990-05-14 1992-02-25 Erbamont Inc. Pharmaceutical composition containing bile acid sequestrant enclosed in a size-exclusion membrane
EP0464299B1 (en) 1990-07-04 1995-01-11 Marcin Krotkiewski Antihypertensive preparation
IE914179A1 (en) 1990-12-07 1992-06-17 Ici Plc Nitrogen derivatives
US5162110A (en) 1990-12-19 1992-11-10 Rhone-Poulenc Rorer Pharmaceuticals Inc. Binding theophylline to ion exchange resins
US5281631A (en) 1991-12-20 1994-01-25 Arch Development Corp. Phosphonic acid based ion exchange resins
RU95107405A (ru) 1992-08-20 1997-02-10 Е. И. Дюпон Де Немур энд Компани (US) Сшитая полимерная аммониевая соль, фармацевтическая композиция, способ снижения содержания холестерина в плазме крови, способ усиления экскреции желчных кислот
WO1994027619A1 (en) 1993-05-20 1994-12-08 Geltex Pharmaceuticals, Inc. Process for adjusting ion concentration in a patient and compositions therefor
US5487888A (en) 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
US5607669A (en) 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US5618530A (en) 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5667775A (en) 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
DK0730494T3 (da) 1993-11-25 1998-09-23 Salternate B V Partikler til binding af monovalente kationer og deres anvendelse
TW474813B (en) 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
US5846990A (en) 1995-07-24 1998-12-08 Bristol-Myers Squibb Co. Substituted biphenyl isoxazole sulfonamides
US6498142B1 (en) 1996-05-06 2002-12-24 Curis, Inc. Morphogen treatment for chronic renal failure
JP3885130B2 (ja) 1996-06-11 2007-02-21 株式会社大塚製薬工場 グアニジノ化合物低下剤並びに水分及びカリウムイオン吸着剤
US6491903B1 (en) 1996-06-27 2002-12-10 Washington University Particles comprising amphiphilic copolymers
US6623759B2 (en) 1996-06-28 2003-09-23 Astrazeneca Ab Stable drug form for oral administration with benzimidazole derivatives as active ingredient and process for the preparation thereof
US5935599A (en) 1996-10-28 1999-08-10 The Board Of Trustees Of The University Of Illinois Polymer-associated liposomes for drug delivery and method of manufacturing the same
JPH10130154A (ja) 1996-10-29 1998-05-19 Otsuka Pharmaceut Factory Inc 腎疾患患者用延命率改善薬
KR100440544B1 (ko) 1998-07-31 2004-07-15 니켄 가가쿠 가부시키가이샤 양이온 교환수지 제제
US6294163B1 (en) 1998-10-02 2001-09-25 Geltex Pharmaceuticals, Inc. Polymers containing guanidinium groups as bile acid sequestrants
ID29778A (id) 1998-11-06 2001-10-11 Searle & Co Pengobatan kombinasi dari penghambat enzim pengubah angiotensi dan antagonis aldosteron untuk menurunkan morbiditas dan mortalitas dari penyakit kardiovaskuler
WO2000040224A1 (en) 1999-01-07 2000-07-13 Elan Corporation, Plc Multiparticulate oral dosage forms
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US20020054903A1 (en) 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
US6569910B1 (en) 1999-10-27 2003-05-27 Basf Aktiengesellschaft Ion exchange resins and methods of making the same
WO2001051063A1 (en) 2000-01-14 2001-07-19 Otsuka Pharmaceutical Factory, Inc. Inhibitors against sodium ion absorption, and preventive or therapeutic agents and foods containing the same
FR2812632B1 (fr) 2000-08-07 2003-03-07 Solvay Procede pour la synthese de composes fluoroorganiques
EP1381376B1 (en) 2000-11-20 2008-01-02 Sorbent Therapeutics, Inc. Water-absorbent polymers and their use
US20040105895A1 (en) 2001-02-06 2004-06-03 Ash Stephen R Monovalent-selective cation exchangers as oral sorbent therapy
US7033639B2 (en) 2001-05-16 2006-04-25 Rohm And Haas Company Polyaniline coating composition
US6881484B2 (en) 2001-05-30 2005-04-19 Mitsubishi Kagaku Iatron, Inc. Core-shell particle including signal-generating substance enclosed therein and process for producing the same
WO2003029172A2 (de) 2001-10-01 2003-04-10 Basf Aktiengesellschaft Verfahren zur herstellung von alkylarylverbindungen und sulfonaten davon
JP2004149525A (ja) 2002-10-09 2004-05-27 Sekisui Chem Co Ltd カリウムイオン吸着剤及びその製造方法、並びに高カリウム血症治療剤
JP5826445B2 (ja) 2003-02-25 2015-12-02 フィンフィーズ フィンランド オイ 擬似移動床システム及び方法
AU2004311849B2 (en) 2003-12-31 2009-04-02 Genzyme Corporation Enteric coated aliphatic amine polymer bile acid sequestrants
EP1732523B9 (en) * 2004-03-30 2010-06-02 Relypsa, Inc. Potassium binding polymers and uses thereof
US7556799B2 (en) 2004-03-30 2009-07-07 Relypsa, Inc. Ion binding polymers and uses thereof
US8192758B2 (en) 2004-03-30 2012-06-05 Relypsa, Inc. Ion binding compositions
US7854924B2 (en) 2004-03-30 2010-12-21 Relypsa, Inc. Methods and compositions for treatment of ion imbalances
US7429394B2 (en) 2004-03-30 2008-09-30 Relypsa, Inc. Ion binding compositions
US8282960B2 (en) 2004-03-30 2012-10-09 Relypsa, Inc. Ion binding compositions
KR20080059265A (ko) * 2005-09-30 2008-06-26 일립사, 인코포레이티드 포유동물의 위장관으로부터 칼륨 이온을 선택적으로제거하기 위한 방법 및 조성물
WO2007038801A2 (en) 2005-09-30 2007-04-05 Ilypsa, Inc. Monovalent cation-binding compositions comprising core-shell particles having crosslinked poly-vinylic shells, and methods of use thereof
US8586097B2 (en) 2005-09-30 2013-11-19 Relypsa, Inc. Methods for preparing core-shell composites having cross-linked shells and core-shell composites resulting therefrom
US20070092553A1 (en) 2005-10-21 2007-04-26 Pfab Lp Compositions and methods of making rapidly dissolving lonically masked formulations
US20070248564A1 (en) 2006-04-25 2007-10-25 Roxane Laboratories, Inc. Formulation of sodium polystyrene sulfonate suspension for the treatment of hyperkalemia
WO2009029829A1 (en) 2007-08-29 2009-03-05 Sorbent Therapeutics, Inc. Polymeric compositions with enhanced saline holding capacity and their method of preparation and use
KR102150184B1 (ko) 2008-08-22 2020-08-31 리립사, 인크. 가교결합된 양이온교환 폴리머, 조성물 및 고칼륨혈증 치료 용도
WO2010022381A1 (en) 2008-08-22 2010-02-25 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties
US8337824B2 (en) 2008-08-22 2012-12-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
US20100111892A1 (en) 2008-08-22 2010-05-06 Relypsa, Inc. Crosslinked polyfluoroacrylic acid and processes for the preparation thereof
WO2010132662A1 (en) * 2009-05-13 2010-11-18 Relypsa, Inc. Powder formulations of potassium-binding active agents
CA2793862C (en) 2010-03-20 2020-07-07 Relypsa, Inc. Continuous process for preparing polyfluoroacrylate particles
US10557856B2 (en) * 2010-09-24 2020-02-11 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Biomarkers of renal injury
US8697132B2 (en) * 2010-12-01 2014-04-15 Shire Llc Capsule and powder formulations containing lanthanum compounds
CA2824441A1 (en) 2011-01-10 2012-07-19 Sorbent Therapeutics, Inc. Compositions comprising crosslinked cation - binding polymers and calcium and/or magnesium cations, and uses thereof
PH12013501762B1 (en) * 2011-02-11 2019-02-06 Zs Pharma Inc Microporous zirconium silicate for the treatment of hyperkalemia
EP2723708B1 (en) 2011-06-27 2019-09-04 Relypsa, Inc. Fluorination of acrylate esters and derivatives
CN103703033A (zh) 2011-06-27 2014-04-02 瑞立普萨公司 用于将聚合酯转化为聚合酸的方法
CA2879425A1 (en) * 2012-07-19 2014-01-23 Relypsa, Inc. Compositions comprising crosslinked cation-binding polymers
EP2916851B1 (en) 2012-10-08 2025-12-17 Vifor (International) Ltd. Potassium-binding agents for treating hypertension and hyperkalemia

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220133345A (ko) 2021-03-24 2022-10-05 강원대학교산학협력단 신규한 페디오코커스 악시딜락티시 균주 및 상기 균주를 이용하여 발효시킨 대두 발효물의 다양한 용도

Also Published As

Publication number Publication date
CN119405686A (zh) 2025-02-11
HK1210705A1 (en) 2016-05-06
EP2916851A2 (en) 2015-09-16
EP2916851B1 (en) 2025-12-17
AU2018260862A1 (en) 2018-12-06
JP2016500672A (ja) 2016-01-14
JP7113871B2 (ja) 2022-08-05
JP6817185B2 (ja) 2021-01-20
US20180193377A1 (en) 2018-07-12
US20170020916A1 (en) 2017-01-26
US9925212B2 (en) 2018-03-27
KR20210005314A (ko) 2021-01-13
US11123363B2 (en) 2021-09-21
WO2014058905A3 (en) 2014-10-30
US10813946B2 (en) 2020-10-27
AU2013329451B2 (en) 2018-08-09
AU2020294307B2 (en) 2022-06-02
US20150110886A1 (en) 2015-04-23
AU2020294307A1 (en) 2021-02-18
US20210038636A1 (en) 2021-02-11
US9492476B2 (en) 2016-11-15
JP6475624B2 (ja) 2019-02-27
US20210046104A1 (en) 2021-02-18
CN104822383A (zh) 2015-08-05
WO2014058905A2 (en) 2014-04-17
JP2020176155A (ja) 2020-10-29
JP2021095421A (ja) 2021-06-24
AU2013329451A1 (en) 2015-04-23
CA2886788A1 (en) 2014-04-17
BR112015007749A2 (pt) 2017-07-04
AU2018260862B2 (en) 2020-10-08
JP2018048211A (ja) 2018-03-29
US20140105848A1 (en) 2014-04-17
CA2886788C (en) 2022-04-19

Similar Documents

Publication Publication Date Title
JP7113871B2 (ja) 高血圧症及び高カリウム血症を治療するためのカリウム結合剤
KR101928973B1 (ko) 가교결합된 양이온교환 폴리머, 조성물 및 고칼륨혈증 치료 용도
WO2010022380A2 (en) Linear polyol stabilized polyfluoroacrylate compositions

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20150504

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
AMND Amendment
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20181005

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20200121

Patent event code: PE09021S01D

AMND Amendment
E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20200706

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20200121

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

X091 Application refused [patent]
AMND Amendment
PX0901 Re-examination

Patent event code: PX09011S01I

Patent event date: 20200706

Comment text: Decision to Refuse Application

Patent event code: PX09012R01I

Patent event date: 20200421

Comment text: Amendment to Specification, etc.

Patent event code: PX09012R01I

Patent event date: 20181005

Comment text: Amendment to Specification, etc.

PX0601 Decision of rejection after re-examination

Comment text: Decision to Refuse Application

Patent event code: PX06014S01D

Patent event date: 20201105

Comment text: Amendment to Specification, etc.

Patent event code: PX06012R01I

Patent event date: 20201005

Comment text: Decision to Refuse Application

Patent event code: PX06011S01I

Patent event date: 20200706

Comment text: Amendment to Specification, etc.

Patent event code: PX06012R01I

Patent event date: 20200421

Comment text: Notification of reason for refusal

Patent event code: PX06013S01I

Patent event date: 20200121

Comment text: Amendment to Specification, etc.

Patent event code: PX06012R01I

Patent event date: 20181005

X601 Decision of rejection after re-examination
A107 Divisional application of patent
J201 Request for trial against refusal decision
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20210105

PJ0201 Trial against decision of rejection

Patent event date: 20210105

Comment text: Request for Trial against Decision on Refusal

Patent event code: PJ02012R01D

Patent event date: 20201105

Comment text: Decision to Refuse Application

Patent event code: PJ02011S01I

Patent event date: 20200706

Comment text: Decision to Refuse Application

Patent event code: PJ02011S01I

Appeal kind category: Appeal against decision to decline refusal

Decision date: 20211027

Appeal identifier: 2021101000018

Request date: 20210105

PN2301 Change of applicant

Patent event date: 20210825

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

J301 Trial decision

Free format text: TRIAL NUMBER: 2021101000018; TRIAL DECISION FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 20210105

Effective date: 20211027

PJ1301 Trial decision

Patent event code: PJ13011S01D

Patent event date: 20211028

Comment text: Trial Decision on Objection to Decision on Refusal

Appeal kind category: Appeal against decision to decline refusal

Request date: 20210105

Decision date: 20211027

Appeal identifier: 2021101000018