KR20150036186A - 유세포 측정법을 이용한 ｒｎａ 측정에 의한 ｔ-세포 활성화에 대한 신속한 검정 - Google Patents

유세포 측정법을 이용한 ｒｎａ 측정에 의한 ｔ-세포 활성화에 대한 신속한 검정 Download PDF

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KR20150036186A
KR20150036186A KR20157001942A KR20157001942A KR20150036186A KR 20150036186 A KR20150036186 A KR 20150036186A KR 20157001942 A KR20157001942 A KR 20157001942A KR 20157001942 A KR20157001942 A KR 20157001942A KR 20150036186 A KR20150036186 A KR 20150036186A
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dna
artificial
cells
synthetic sequence
cell
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유리 부쉬킨
마리아 로라 겐나로
산쟈이 티야기
리챠드 파인
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러트거즈,더스테이트유니버시티오브뉴저지
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6866—Interferon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR20157001942A 2012-06-27 2013-06-26 유세포 측정법을 이용한 ｒｎａ 측정에 의한 ｔ-세포 활성화에 대한 신속한 검정 Ceased KR20150036186A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261665231P 2012-06-27 2012-06-27
US61/665,231 2012-06-27
US201361784802P 2013-03-14 2013-03-14
US61/784,802 2013-03-14
PCT/US2013/047774 WO2014004609A2 (en) 2012-06-27 2013-06-26 Rapid assays for t-cell activation by rna measurements using flow cytometry

Publications (1)

Publication Number Publication Date
KR20150036186A true KR20150036186A (ko) 2015-04-07

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KR20157001942A Ceased KR20150036186A (ko) 2012-06-27 2013-06-26 유세포 측정법을 이용한 ｒｎａ 측정에 의한 ｔ-세포 활성화에 대한 신속한 검정

Country Status (12)

Country Link
US (2) US10900072B2 (OSRAM)
EP (2) EP2867374B1 (OSRAM)
JP (1) JP6464081B2 (OSRAM)
KR (1) KR20150036186A (OSRAM)
CN (2) CN104662170A (OSRAM)
AU (2) AU2013280416B2 (OSRAM)
BR (1) BR112014032677A2 (OSRAM)
CA (1) CA2877933A1 (OSRAM)
IN (1) IN2015KN00073A (OSRAM)
RU (1) RU2671707C2 (OSRAM)
WO (1) WO2014004609A2 (OSRAM)
ZA (1) ZA201500239B (OSRAM)

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BR112014019168B1 (pt) 2012-02-03 2021-10-05 California Institute Of Technology Método capaz de detectar de forma não degenerada presença ou ausência de analitos em um único volume de amostra e método de detecção da presença ou ausência de cada analito dentre uma pluralidade de analitos
EP3901243A1 (en) 2012-08-03 2021-10-27 California Institute of Technology Multiplexing and quantification in pcr with reduced hardware and requirements
CN106198358B (zh) * 2016-06-24 2019-02-15 北京大学 基于"石英杯中激发型"流式细胞分选仪的染色体分选方法
CN108732082A (zh) * 2018-06-07 2018-11-02 北京唯公医疗技术有限公司 细胞分群方法
US12203129B2 (en) * 2018-07-03 2025-01-21 ChromaCode, Inc. Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays
JP7457572B2 (ja) * 2019-05-27 2024-03-28 住友化学株式会社 光学フィルムの反りの測定方法、及び、測定装置
WO2021046121A1 (en) * 2019-09-03 2021-03-11 The Regents Of The University Of California Method to sequence mrna in single cells in parallel with quantification of intracellular phenotype
JP2023500456A (ja) * 2019-10-29 2023-01-06 ウニベルジテート ハイデルベルク 人工抗原提示分子とその利用
CN111999235A (zh) * 2020-07-03 2020-11-27 青岛农业大学 一种利用流式细胞术快速检测有活力的食用菌原生质体数量的方法
RU2766781C1 (ru) * 2021-03-03 2022-03-15 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр кардиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ кардиологии" Минздрава России) Способ выявления поражения сосудистого эндотелия
WO2022271272A1 (en) * 2021-06-22 2022-12-29 Nantcell, Inc. Rapid test for patient cd8 t-cell activation, systems and methods

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US4994369A (en) * 1987-12-15 1991-02-19 The Board Of Trustees Of The Leland Stanford Jr. Univ. T-cell activation related gene
US5866331A (en) 1995-10-20 1999-02-02 University Of Massachusetts Single molecule detection by in situ hybridization
JP3869092B2 (ja) * 1996-10-01 2007-01-17 ジェロン・コーポレーション ヒトテロメラーゼ触媒性サブユニット
US6610839B1 (en) * 1997-08-14 2003-08-26 Geron Corporation Promoter for telomerase reverse transcriptase
US7514232B2 (en) * 1996-12-06 2009-04-07 Becton, Dickinson And Company Method for detecting T cell response to specific antigens in whole blood
UA84387C2 (ru) 1999-03-09 2008-10-27 Займодженетикс, Инк. Человеческий цитокин как лиганд зальфа рецептора и его применение
RU2258710C2 (ru) * 1999-03-09 2005-08-20 Займодженетикс, Инк. Новый цитокин zalpha11-лиганд
EP1502109A4 (en) 2002-04-19 2007-01-10 Scripps Research Inst COMPOSITIONS AND METHODS ASSOCIATED WITH SIGNALING OF ENDOTHELIAL CELLS USING THE PROTEASE-ACTIVATED RECEPTOR (PAR1)
CA2492848C (en) * 2002-08-08 2012-01-24 Baylor College Of Medicine Isolation and identification of t cells
EP1765988B1 (en) * 2004-05-27 2017-09-20 The Trustees of The University of Pennsylvania Novel artificial antigen presenting cells and uses therefor
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ES2330013T3 (es) * 2005-09-05 2009-12-03 Immatics Biotechnologies Gmbh Peptidos asociados a tumores unidos a moleculas del antigeno de leucocito humano (hla) de clase i o ii y vacunas contra el cancer relacionadas.
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WO2012092458A2 (en) * 2010-12-30 2012-07-05 Anthrogenesis Corporation Compositions comprising placental stem cells and platelet rich plasma, and methods of use thereof
WO2012162779A1 (en) * 2011-05-27 2012-12-06 The University Of British Columbia Microfluidic cell trap and assay apparatus for high-throughput analysis
JP5344007B2 (ja) * 2011-06-30 2013-11-20 株式会社デンソー 近距離無線通信装置

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Publication number Publication date
AU2017228677A1 (en) 2017-10-05
EP3828278A1 (en) 2021-06-02
CA2877933A1 (en) 2014-01-03
ZA201500239B (en) 2015-12-23
BR112014032677A2 (pt) 2019-01-15
JP2015522284A (ja) 2015-08-06
CN108624654A (zh) 2018-10-09
RU2015102447A (ru) 2016-08-20
IN2015KN00073A (OSRAM) 2015-07-31
RU2671707C2 (ru) 2018-11-06
AU2017228677B2 (en) 2019-02-14
CN104662170A (zh) 2015-05-27
WO2014004609A2 (en) 2014-01-03
JP6464081B2 (ja) 2019-02-06
US20160201122A1 (en) 2016-07-14
EP2867374A2 (en) 2015-05-06
EP2867374A4 (en) 2016-05-11
WO2014004609A3 (en) 2014-02-27
US10900072B2 (en) 2021-01-26
US20210139965A1 (en) 2021-05-13
US11767551B2 (en) 2023-09-26
AU2013280416B2 (en) 2017-06-15
EP2867374B1 (en) 2020-10-28
AU2013280416A1 (en) 2015-02-05

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