KR20140109958A - 대장암의 시험관내 진단 또는 예후 예측 방법 - Google Patents

대장암의 시험관내 진단 또는 예후 예측 방법 Download PDF

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KR20140109958A
KR20140109958A KR1020147019401A KR20147019401A KR20140109958A KR 20140109958 A KR20140109958 A KR 20140109958A KR 1020147019401 A KR1020147019401 A KR 1020147019401A KR 20147019401 A KR20147019401 A KR 20147019401A KR 20140109958 A KR20140109958 A KR 20140109958A
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프랑수아 말레
나탈리 뮈제니에
필립 페호
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Abstract

본 발명은 1종 이상의 HERV 핵산 서열의 발현 산물 1종 이상을 검출하는 단계를 포함하는 대장암을 시험관내에서 진단하거나 예후를 예측하는 방법, 분자 마커/분자 마커들로서 상기 분리된 핵산 서열의 용도, 및 HERV 핵산 서열의 발현 산물 1종 이상에 대한 특이적인 결합 파트너 1종 이상을 포함하는 키트에 관한 것이다.

Description

대장암의 시험관내 진단 또는 예후 예측 방법 {METHOD FOR IN VITRO DIAGNOSIS OR PROGNOSIS OF COLON CANCER}
내인성 레트로바이러스 (endogenous retroviruse)는, 프로바이러스 형태로 생식계 세포에 삽입 (integration)되어, 이러한 방식을 통해 숙주 자손의 게놈으로 전달된, 감염성 레트로바이러스의 자손에 해당된다.
인간 게놈의 서열 분석을 통해 상당히 많은 양의 트랜스포존 인자나 이의 유도체들이 알려지게 되었다. 실제, 반복 서열들이 인간 게놈의 절반에 가까우며, 내인성 레트로바이러스 및 레트로트랜스포존이 게놈의 8%를 차지하고 있으며, 현 재 이들 인자들의 갯수는 400,000개 이상에 이른다.
인간 게놈에 현재 존재하는 내인성 레트로바이러스 인자 (ERV)들이 많은 것은, 인간 계통이 진화하는 동안 성공적으로 이루어진 약 100건의 내생화 (endogenization)의 결과이다. 다양한 유형의 내생화가 지금으로부터 2백만 - 9천만년전에 이르는 기간 동안 전개되어 왔으며, "복사/붙이기" 유형의 현상들을 통해 카피수 증가로 이어졌으며, 에러 발생 가능성은, 조상이 되는 프로바이러스에서 시작하여 HERV 패밀리, 즉 서열 상동성을 나타내는 인자들의 세트를 형성하게 되었다. 가장 오래된 인자인 HERV-L 패밀리의 인자들은 아마 포유류가 출현하기 전에 삽입되었을 것이다. 2종의 패밀리, HERV-F와 HERV-H는 최초의 영장류가 그 모습을 드러내는 시기에 나타났다. HERV-FRD 및 HERV-K(HML-5) 패밀리들은, 4천만 내지 5천 5백만년 전에 생식계 세포에 삽입된 것으로, 고등 영장류에서 특이적이다. 한편, HERV-W 및 HERV-E 패밀리는, 예를 들어, 신세계 원숭이가 분리된 후, 5백만 내지 천만년 이후에 삽입되었으며, 협비원류 (Catarrhini) (유인종 및 긴꼬리원숭이과)에 특이적이다.
ERV 서열은 모든 염색체에 존재하며, 패밀리에 따라 밀집도에 차이가 있지만, ERV의 물리적 근접성과 이의 계통발생적 근접성 간에는 연관성이 없다.
오랜 기간 동안, ERV는 기생체로 또는 단지 DNA 폐기물로 간주되어 왔다. 그럼에도 불구하고, 유기체에서의 ERV의 영향은 과거 게놈을 모델링하는데 있어서의 참여 또는 여전히 지원가능한 유해한 재조합으로만 한정되지는 않는다.
ERV의 풍부성과 구조적 복잡성으로 인해 이의 발현은 분석하기가 매우 어려우며, 종종 해석하기도 어렵다. HERV 발현이 검출된다는 것은 동일 패밀리에서 하나 이상의 유전자 좌의 전사 활성화를 나타내는 것일 수 있다. 활성화된 유전자 좌들 또는 유전자 좌는 조직 및/또는 상황에 따라 달라질 수 있다.
Nickerson,D.A., Taylor,S.L., Weiss,K.M., Clark,A.G., Hutchinson,R.G., Stengard,J., Salomaa,V., Vartiainen,E., Boerwinkle,E. and Sing,C.F. (1998) DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene. Nat. Genet., 19, 233-240. Navarro,G. and Raffinot,M. (2002) Flexible Pattern Matching in Strings: Practical On-Line Search Algorithms for Texts and Biological Sequences. Cambridge University Press. Irizarry,R.A., Hobbs,B., Collin,F., Beazer-Barclay,Y.D., Antonellis,K.J., Scherf,U. and Speed,T.P. (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics (Oxford, England), 4, 249-264. Johnson,W.E., Li,C. and Rabinovic,A. (2007) Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics (Oxford, England), 8, 118-127. Tusher,V.G., Tibshirani,R. and Chu,G. (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proceedings of the National Academy of Sciences of the United States of America, 98, 5116-5121. Storey,J.D. and Tibshirani,R. (2003) Statistical significance for genomewide studies. Proceedings of the National Academy of Sciences of the United States of America, 100, 9440-9445.
본 발명자들은, 내인성 레트로바이러스 인자들로 정확하게 동정된 유전자 좌에 해당되는 핵산 서열이 대장암과 관련있으며, 이들 서열이 병리학적 상태에 대한 분자 마커라는 것을, 발견하여, 입증하게 되었다. 동정된 서열은 프로바이러스, 즉, 5' 및 3' 위치에서 긴 말단 반복체 (LTR: long terminal repeat)의 측면에 위치한 gag, pol 및 env 유전자들을 전체 또는 일부 포함하는 서열이거나, 또는 LTR이나 동정된 유전자의 전체 또는 일부를 포함하는 서열이다. 동정된 DNA 서열은 서열목록에서 서열번호 1 - 285로 각각 언급되며, 암 샘플과 정상 샘플 간의 "발현 비율"을 발현, 과다 발현 또는 저발현 (underexpression)으로 나타낸 바와 같이, 아래 표 (NCBI 36/hg18)에 이들의 염색체 위치를 나타낸다. 핵산의 발현 또는 핵산의 발현 변화가 대장 조직에 특이적인 경우, 이러한 정보는 타겟 조직 칸에 기호 "x"로 표시되어 있다. 이는, 대상 핵산의 발현 또는 발현 변화가 대장 조직 이외의 다른 생물학적 구획에서 확인된다면, 이는 간접적으로 대장암의 신호 (signature)이다. 대장 조직에 특이적인 것으로 동정된 DNA 서열들은 서열목록에서 각각 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 언급된다. 대장 조직에 특이적이지 않은 것으로 동정된 DNA 서열들은 각각 서열번호 6, 14, 15, 16, 18, 20, 21, 23, 26, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284 및 285로 언급된다.
서열번호 염색체 위치 타겟 조직 암/정상 발현 비율
1 (-) chr 5: 135904531-135912105 x 43.8
2 (-) chr 1: 4468515-4474361 x 34.7
3 (-) chr 20: 19680691-19685420 x 19.4
4 (+) chr 4: 183972457-183977066 x 12.5
5 (+) chr 13: 108715439-108721465 x 10.9
6 (-) chr 1: 204451670-204454441 -8.6
7 (-) chr 7: 26030345-26035880 x 8.4
8 (+) chr 14: 73239795-73245370 x 8.3
9 (-) chr 5: 179775292-179781337 x 7.7
10 (-) chr 14: 30785319-30790095 x 7.6
11 (-) chr 3: 45773285-45774220 x 6.7
12 (+) chr 16: 84869202-84872386 x 6.4
13 (-) chr 11: 130128601-130134242 x 5.9
14 (-) chr 10: 6711545-6717509 5.7
15 (+) chr 8: 86591572-86592049 -5.6
16 (+) chr 12: 25207414-25213718 5.6
17 (+) chr 8: 98256433-98262143 x 4.9
18 (+) chr 1: 201726731-201727141 -4.8
19 (-) chr 8: 80460894-80463081 x 4.8
20 (+) chr 8: 105367316-105373215 4.8
21 (+) chr 17: 11815798-11820989 4.7
22 (-) chr 18: 24526989-24532843 x 4.5
23 (+) chr 22: 15472270-15476039 4.2
24 (-) chr 8: 91171628-91177272 x 4.2
25 (+) chr 1: 176275999-176281686 x 4.2
26 (-) chr 19: 48519503-48525376 4.1
27 (+) chr 9: 25658927-25666384 x 3.7
28 (+) chr 13: 34271392-34275485 3.7
29 (-) chr 11: 60237235-60238528 -3.6
30 (+) chr 8: 116896352-116900252 3.2
31 (+) chr 19: 60146916-60147844 3.2
32 (+) chr 2: 188084458-188084785 -3.1
33 (+) chr 10: 98482752-98486365 2.9
34 (-) chr 8: 99671725-99672015 2.9
35 (-) chr 13: 55586741-55590394 2.8
36 (-) chr X: 93840473-93846744 -2.8
37 (-) chr 4: 93411664-93417822 2.5
38 (+) chr 4: 121134267-121140271 2.5
39 (-) chr 5: 135912105-135915610 2.5
40 (-) chr 6: 82110364-82117596 -2.4
41 (-) chr 6: 123945178-123950851 2.4
42 (-) chr 2: 71238414-71246247 2.4
43 (-) chr 1: 171684177-171684627 -2.3
44 (+) chr 10: 65936583-65936972 2.3
45 (+) chr 14: 50429630-50433350 2.3
46 (+) chr 14: 41054824-41060836 2.3
47 (-) chr 5: 34514678-34514916 2.2
48 (+) chr 8: 115366935-115369140 2.2
49 (-) chr 11: 73926652-73927082 2.2
50 (-) chr 14: 22736836-22737207 2.2
51 (-) chr 1: 79726879-79732396 2.2
52 (+) chr 3: 130161351-130164778 2.1
53 (-) chr 12: 11656097-11659027 -2.1
54 (-) chr 17: 72113663-72119188 2.1
55 (-) chr 11: 123241237-123246982 2.1
56 (-) chr 8: 136848614-136854437 2.1
57 (+) chr 3: 135222763-135223084 -2.1
58 (+) chr 12: 94666771-94672799 2.1
59 (+) chr 6: 63559535-63565316 -2.1
60 (-) chr 2: 54587807-54590183 -2.0
61 (+) chr 2: 173115073-173117251 2.0
62 (+) chr 5: 755586-759445 2.0
63 (+) chr 8: 129995887-130001750 2.0
64 (+) chr 4: 127503905-127504662 2.0
65 (-) chr 21: 41718929-41719369 2.0
66 (+) chr 20: 40489715-40490155 2.0
67 (+) chr 7: 100274888-100276065 2.0
68 (+) chr 7: 35702274-35703153 2.0
69 (+) chr 6: 131686129-131689771 -2.0
70 (-) chr 1: 226879232-226884835 2.0
71 (-) chr 10: 17712042-17714165 1.9
72 (-) chr 10: 53463521-53469327 1.9
73 (-) chr X: 112238600-112244308 1.9
74 (-) chr 1: 146722974-146723946 1.9
75 (+) chr 1: 53671142-53673436 1.9
76 (-) chr X: 91414738-91420449 -1.9
77 (-) chr 7: 16683220-16684043 1.9
78 (+) chr 10: 100097920-100098685 1.9
79 (+) chr 22: 31228741-31234490 1.8
80 (-) chr 13: 112501931-112502014 1.8
81 (+) chr 1: 146832410-146833382 1.8
82 (-) chr 10: 20449793-20453869 1.8
83 (+) chr 9: 21911892-21921934 1.8
84 (-) chr 3: 186574589-186580188 -1.8
85 (-) chr 10: 62463482-62469677 -1.8
86 (-) chr 15: 97959745-97960384 -1.7
87 (+) chr 17: 75988189-75996283 -1.7
88 (+) chr 2: 88760597-88762729 1.7
89 (+) chr 7: 29791133-29794522 1.7
90 (+) chr 18: 50528195-50528890 -1.7
91 (+) chr 1: 89162808-89170138 -1.7
92 (-) chr 3: 178866314-178871614 -1.7
93 (-) chr 19: 52245264-52250506 1.7
94 (+) chr 17: 30852752-30853047 -1.7
95 (-) chr 11: 69581214-69582655 1.7
96 (+) chr 5: 138886787-138888726 -1.7
97 (-) chr 3: 167701085-167706900 x 1.7
98 (+) chr 1: 101404629-101404696 1.7
99 (+) chr 8: 113277279-113282810 -1.6
100 (-) chr 20: 740491-741481 1.6
101 (-) chr 2: 58194071-58199769 1.6
102 (+) chr 13: 35788462-35794330 -1.6
103 (+) chr 9: 12938344-12944129 1.6
104 (-) chr 9: 116976750-116982362 -1.6
105 (-) chr 4: 11264289-11269976 -1.6
106 (-) chr 1: 223094264-223100407 -1.6
107 (+) chr 7: 92862465-92866875 1.6
108 (-) chr 17: 72296838-72297401 -1.6
109 (+) chr X: 86823336-86830473 1.6
110 (-) chr X: 89718079-89718557 -1.6
111 (-) chr 3: 58397972-58398349 -1.6
112 (-) chr 2: 215413351-215413804 -1.6
113 (+) chr 4: 87614948-87620699 1.6
114 (-) chr 1: 54874382-54875358 -1.6
115 (+) chr 1: 237429952-237430254 1.6
116 (-) chr 7: 79651365-79652053 -1.6
117 (-) chr 4: 180711319-180712287 -1.5
118 (-) chr 5: 146727162-146727562 -1.5
119 (+) chr 3: 156178559-156179784 -1.5
120 (+) chr 1: 51465235-51468757 -1.5
121 (-) chr 3: 100178327-100178459 1.5
122 (-) chr 4: 67932305-67932737 1.5
123 (-) chr 18: 24532993-24533490 1.5
124 (-) chr 12: 20862483-20866818 1.5
125 (-) chr 12: 8334466-8337953 -1.5
126 (-) chr 13: 94759022-94759378 -1.5
127 (-) chr 1: 144779633-144780605 1.5
128 (+) chr 1: 143314771-143315743 1.5
129 (+) chr 2: 231645891-231645949 1.5
130 (-) chr 7: 65721380-65722348 -1.5
131 (+) chr 2: 188606470-188612115 -1.5
132 (-) chr 3: 176879333-176879730 -1.5
133 (-) chr 3: 186765708-186772209 1.5
134 (-) chr 11: 67377518-67381008 1.5
135 (-) chr 12: 123157590-123158004 1.5
136 (+) chr 7: 134507781-134510522 -1.5
137 (+) chr 12: 112980007-112980079 -1.5
138 (-) chr 10: 101571639-101577563 1.5
139 (+) chr 8: 81814506-81817982 -1.5
140 (-) chr 12: 29178820-29185001 -1.5
141 (-) chr 5: 119558433-119559245 -1.5
142 (-) chr 13: 23891789-23892035 1.5
143 (-) chr 1: 51845967-51846990 -1.5
144 (-) chr 19: 58630272-58630359 1.5
145 (-) chr 3: 193273756-193277341 -1.5
146 (+) chr 6: 149002601-149008339 -1.5
147 (+) chr 3: 186986788-186987217 1.5
148 (-) chr 3: 192866741-192872861 1.5
149 (+) chr 4: 69952306-69955060 -1.4
150 (-) chr 14: 38837505-38837576 1.4
151 (+) chr 2: 57102769-57103266 -1.4
152 (-) chr 3: 130032422-130036475 -1.4
153 (+) chr 4: 54112155-54112817 -1.4
154 (-) chr 3: 146311752-146313676 1.4
155 (-) chr 12: 14769094-14769447 1.4
156 (+) chr 13: 55512386-55518412 1.4
157 (+) chr 15: 72433538-72439180 -1.4
158 (+) chr 3: 40577391-40583175 -1.4
159 (-) chr 4: 120675771-120676048 -1.4
160 (-) chr 8: 12395268-12398823 -1.4
161 (-) chr X: 101106329-101106710 1.4
162 (-) chr 3: 190138663-190139459 -1.4
163 (-) chr 3: 98473995-98479084 -1.4
164 (+) chr 10: 5070454-5070498 -1.4
165 (+) chr 5: 114710170-114711150 1.4
166 (+) chr 3: 128381736-128382403 -1.4
167 (+) chr 9: 22813029-22813838 -1.4
168 (-) chr 2: 231673651-231673769 1.4
169 (+) chr 3: 116946112-116948448 1.4
170 (-) chr 11: 92482373-92482685 1.4
171 (+) chr 4: 167867005-167868159 1.4
172 (-) chr 1: 144779633-144780605 1.4
173 (+) chr 20: 58157372-58158054 1.4
174 (-) chr 4: 138339335-138340015 -1.4
175 (-) chr 12: 71688770-71689742 1.4
176 (+) chr 13: 63310225-63315979 -1.4
177 (-) chr 1: 110201971-110202287 -1.4
178 (+) chr 10: 92557026-92562997 -1.4
179 (+) chr 1: 38146074-38152175 -1.4
180 (+) chr 6: 153045773-153046224 1.4
181 (-) chr 1: 79934615-79940335 -1.4
182 (+) chr 4: 155197148-155204405 -1.4
183 (+) chr 13: 40927858-40928571 1.4
184 (+) chr 4: 11974611-11980403 -1.3
185 (+) chr 18: 4676671-4682409 -1.3
186 (-) chr 21: 14575132-14576104 -1.3
187 (+) chr 5: 180186875-180187838 -1.3
188 (+) chr 4: 68579259-68585888 -1.3
189 (-) chr 11: 27607193-27613049 -1.3
190 (+) chr 18: 6123610-6123972 -1.3
191 (+) chr 14: 57658752-57662615 -1.3
192 (-) chr 1: 144213068-144214036 -1.3
193 (-) chr 4: 62312529-62318338 -1.3
194 (+) chr 1: 45751770-45752724 -1.3
195 (-) chr 17: 6577008-6581495 -1.3
196 (-) chr 1: 244819996-244820439 -1.3
197 (-) chr 9: 100067414-100073409 1.3
198 (+) chr 3: 196356095-196356926 -1.3
199 (+) chr 12: 31851416-31851846 -1.3
200 (-) chr 5: 118311697-118316179 -1.3
201 (-) chr 1: 94806343-94810970 -1.3
202 (+) chr 2: 185332604-185332980 -1.3
203 (+) chr 4: 107250443-107255274 -1.3
204 (-) chr 18: 31472178-31472680 -1.3
205 (+) chr 6: 38501905-38502660 -1.3
206 (-) chr 15: 49734758-49735530 1.3
207 (-) chr X: 84258326-84258441 -1.3
208 (+) chr 5: 55618832-55619003 -1.3
209 (-) chr 17: 16678919-16679896 1.3
210 (+) chr 2: 193715387-193716358 -1.3
211 (+) chr 5: 115014416-115019003 1.3
212 (+) chr 17: 22039285-22039750 -1.3
213 (+) chr 5: 108685641-108685853 -1.3
214 (+) chr 10: 65474521-65475382 -1.3
215 (-) chr 6: 89180631-89187940 1.3
216 (+) chr 1: 244312610-244313561 1.3
217 (+) chr 5: 76822592-76823033 -1.3
218 (-) chr Y: 4283432-4289271 -1.3
219 (+) chr 5: 71075676-71076376 -1.3
220 (+) chr 2: 24861412-24861769 -1.3
221 (-) chr 1: 110196377-110201971 -1.3
222 (+) chr 3: 177261846-177267467 -1.3
223 (+) chr 7: 6908153-6909119 -1.3
224 (-) chr 12: 33132053-33135058 -1.3
225 (-) chr 7: 146321019-146321687 1.3
226 (+) chr 4: 54581003-54585874 -1.3
227 (+) chr X: 138823266-138823672 -1.3
228 (+) chr 18: 2829330-2829995 -1.3
229 (+) chr 6: 66335631-66336029 -1.3
230 (-) chr 6: 121983265-121989145 -1.3
231 (-) chr 2: 226039745-226040459 -1.3
232 (+) chr 4: 109853300-109855458 1.3
233 (+) chr 19: 20126744-20133095 -1.3
234 (-) chr 11: 14839752-14840420 -1.2
235 (-) chr 3: 20380459-20380671 -1.2
236 (+) chr 4: 53395726-53396112 -1.2
237 (+) chr 19: 9553879-9554314 1.2
238 (-) chr 2: 63928103-63928550 -1.2
239 (+) chr 3: 187581597-187582311 -1.2
240 (-) chr 5: 76211738-76218598 -1.2
241 (+) chr 17: 18280923-18281897 1.2
242 (-) chr 4: 178566070-178566839 -1.2
243 (+) chr 12: 60267154-60272981 -1.2
244 (+) chr 18: 27623185-27623837 -1.2
245 (-) chr 5: 135094585-135101074 -1.2
246 (+) chr 10: 4962301-4962771 -1.2
247 (-) chr 5: 153996685-154003250 -1.2
248 (-) chr 6: 5981329-5981780 -1.2
249 (-) chr 8: 828875-829287 -1.2
250 (+) chr 18: 38295804-38303710 -1.2
251 (-) chr 3: 54643549-54649271 -1.2
252 (-) chr 18: 68050597-68051144 -1.2
253 (-) chr 3: 46260865-46268560 -1.2
254 (-) chr 21: 40033061-40040223 -1.2
255 (+) chr 1: 148879269-148880889 1.2
256 (-) chr 2: 44343693-44344377 1.2
257 (-) chr 11: 80087903-80088662 -1.2
258 (+) chr 3: 46140179-46140255 -1.2
259 (+) chr 10: 45388242-45391541 -1.2
260 (-) chr 10: 52210114-52210776 1.2
261 (-) chr 3: 163923299-163927462 -1.2
262 (-) chr 18: 22761239-22762201 -1.2
263 (+) chr 5: 64505763-64506756 -1.2
264 (-) chr 16: 18909966-18916124 -1.2
265 (+) chr 5: 119114744-119115548 -1.2
266 (+) chr 1: 69101725-69102525 -1.2
267 (+) chr 1: 161827723-161832945 -1.2
268 (+) chr 1: 223140681-223147414 -1.2
269 (+) chr Y: 26648032-26648192 -1.2
270 (-) chr 2: 195907646-195913044 -1.2
271 (-) chr 7: 54710388-54711318 -1.2
272 (-) chr 8: 34837245-34837699 1.2
273 (+) chr 4: 27585609-27586295 -1.2
274 (+) chr 6: 160569673-160575346 -1.2
275 (-) chr 2: 167330763-167331232 -1.1
276 (-) chr 21: 16686151-16692725 -1.1
277 (-) chr 3: 180722967-180726830 -1.1
278 (+) chr 13: 61603944-61604298 -1.1
279 (-) chr Y: 15720288-15724345 -1.1
280 (-) chr 1: 115355475-115355826 1.1
281 (+) chr Y: 26648032-26648192 -1.1
282 (+) chr 11: 94682231-94690615 -1.1
283 (-) chr 18: 62088302-62089092 1.1
284 (+) chr 19: 49834194-49835177 -1.1
285 (-) chr 11: 69737702-69743910 -1.1
따라서, 본 발명은, 하나 이상의 핵산 서열에 대한 하나 이상의 발현 산물을 검출하는 단계를 포함하는, 환자로부터 취득한 생물학적 샘플에서 대장암을 시험관내 진단하는 방법 또는 대장암의 중등도에 대한 예후를 예측하는 시험관내 방법에 관한 것으로, 상기 핵산 서열은 서열번호 1 - 285로 표시된 서열 또는 서열번호 1 - 285로 표시된 서열들 중 하나와 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 보다 바람직하게는 99.6% 이상의 또는 99.7% 이상의 동일성을 가지는 서열들 중에서 선택된다.
진단은 개체가 질환에 걸렸는지 여부를 확인할 수 있게 해준다. 예후 예측은 개체의 생존 및/또는 삶의 질에 영향을 미치는 질환의 중등도 정도 (등급 및/또는 병기)를 확인할 수 있게 해준다. 본 발명에서, 진단은 매우 초기일 수 있다.
전술한 동일성 %는 게놈의 뉴클레오티드 다양성을 고려하여 결정된 것이다. 뉴클레오티드 다양성은 반복 서열을 포함하지 않는 영역 보다는 반복 서열이 다량 함유된 게놈의 영역에서 더 높은 것으로 알려져 있다. 예를 들어, Nickerson D. A. et al. (1)에서는, 반복 서열을 포함한 영역에서의 다양성이 대략 0.3% (0.32%)임을 언급하였다.
상기 나타낸 서열들 각각의 암성 상태를 식별하는 식별력은 SAM 절차 (5)를 이용한 다음, 위 양성율로 보정하고 (6), 26 보다 낮은 값은 제외함으로써, 통계학적 분석으로 입증한다. 따라서, 상기 나타낸 각각의 서열은 종양 상태 및 정상 상태 간에 유의한 발현 차이를 나타낸다. 이로써, 전술한 서열들 중 하나의 서열에서 관찰되는 발현 차이는 병리학적 상태에 대한 신호가 된다. 물론, 전술한 서열들 수개에 대한 발현 차이를 조합하는 것도, 예를 들어, 열거된 서열들 중 2, 3, 4, 5, 6, 7, 8, 9, 10개 또는 그 이상에서 심지어 최대 285개로 구성된 한가지 이상의 조합, 바람직하게는 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 나타낸 각각의 서열들의 2, 3, 4, 5, 6, 7, 8, 9, 10개 또는 그 이상에서 심지어 최대 18개로 구성된 한가지 이상의 조합도 가능하다.
특히, 서열번호 2, 3 및 8로 나타낸 서열들은, 단독으로 또는 조합하여 (2개 또는 3개 모두) 한가지 이상의 바람직한 신호를 형성한다.
즉, 본 발명의 방법에서, 2종 이상의 핵산 서열들에 대한 각각의 발현 산물 2종 이상을 검출하며, 상기 핵산 서열은 서열번호 1 - 285로 나타낸 서열들로부터 선택되거나, 또는 서열번호 1 - 285로 표시된 서열들 중 하나와 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 보다 바람직하게는 99.6% 이상의 또는 99.7% 이상의 동일성을 가지는 서열들 중에서 선택된다.
본 발명에 따른 방법의 일 구현예에서, 2종 이상의 핵산 서열에 대한 발현 산물을 검출하며, 상기 2종 이상의 핵산 서열은 대장 조직에 특이적인 것으로 동정된 서열들로부터 선택되며, 즉 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 나타낸 서열들의 그룹으로부터 또는 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 표시된 서열들 중 하나와 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 보다 바람직하게는 99.6% 이상의 또는 99.7% 이상의 동일성을 가지는 서열들 중에서 선택된다.
본 발명에 따른 방법의 다른 구현예에서, 대장 조직에 특이적인 것으로 동정된 서열들로부터 선택되는, 즉 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 나타낸 서열들의 그룹으로부터 선택되는, 또는 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 표시된 서열들 중 하나와 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 보다 바람직하게는 99.6% 이상의 또는 99.7% 이상의 동일성을 가지는 서열들 중에서 선택되는, 하나 이상의 서열에 대한 발현 산물과, 대장 조직에 특이적이지 않은 것으로 동정된 서열들로부터 선택되는, 즉, 서열번호 6, 14, 15, 16, 18, 20, 21, 23, 26, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284 및 285로 나타낸 서열들의 군으로부터 선택되는, 또는 서열번호 6, 14, 15, 16, 18, 20, 21, 23, 26, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284 및 285로 표시된 서열들 중 하나와 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 보다 바람직하게는 99.6% 이상의 또는 99.7% 이상의 동일성을 가지는 서열들로부터 선택되는, 하나 이상의 서열에 대한 발현 산물을 검출한다.
특히, 본 발명의 방법에서, 하나 이상의 핵산 서열, 바람직하게는 2종 이상의 핵산 서열, 또는 3종의 핵산 서열의 발현 산물을 검출하며, 상기 핵산 서열은 서열번호 2, 3 및 8로 표시된 서열들의 군으로부터, 또는 서열번호 2, 3 및 8로 표시된 서열들 중 하나와 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 보다 바람직하게는 99.6% 이상의 또는 99.7% 이상의 동일성을 가지는 서열들 중에서 선택된다.
검출하는 발현 산물은 1종 이상의 RNA 전사체, 특히 1종 이상의 mRNA 또는 1종 이상의 폴리펩타이드이다.
발현 산물이 mRNA 전사체인 경우, 이는 혼성화, 서열 분석 또는 증폭 등의 임의의 적절한 방법으로 검출한다. mRNA는, 소정의 실험 조건에서 mRNA 전사체에 혼성화하도록 설계된, 1종 이상의 프로브 및/또는 1종 이상의 프라이머와 접촉시키고, mRNA에 대한 혼성화 존재 또는 부재를 확인한 다음, 선택적으로 mRNA를 정량함으로써, 직접 검출할 수 있다. 바람직한 방법들 중에서도, 증폭 (예, RT-PCR, NASBA 등), 칩에서의 혼성화 또는 기타 서열분석을 언급할 수 있다. mRNA는 또한 cDNA 카피 등의 전사체로부터 유래된 핵산을 이용하여 간접적으로 검출할 수 있다.
일반적으로, 본 발명의 방법은 분석할 샘플에서 mRNA를 추출하는 일차 단계를 포함한다.
즉, 본 방법은,
(i) 분석할 샘플로부터 mRNA를 추출하는 단계,
(ii) 분석할 샘플로부터 mRNA를 검출 및 정량하는 단계,
(iii) 동일 개체에서 기원한 건강한 샘플일 수 있는 기준 샘플에서 mRNA를 추출하는 단계, 또는
(iv) 상기 건강한 샘플에서 mRNA를 검출 및 정량하는 단계,
(v) 분석할 샘플과 기준 샘플에서 발현되는 mRNA의 양을 비교하는 단계를 포함할 수 있으며, 분석할 샘플에서 발현되는 mRNA의 양이 건강한 기준 샘플에서 발현되는 mRNA 양과 차이가 있는 측정 결과는, 대장암의 중등도의 진단 또는 예후 예측과 연관시킬 수 있으며 (건강한 대장 조직에서의 mRNA 발현량 대비 암성 대장 조직에서의 mRNA의 양 차이는 발현, 과다 발현 또는 저발현과는 무관함);
특히,
(i) 샘플로부터 분석할 mRNA를 추출하는 단계,
(ii) 분석할 mRNA에서, 샘플내 1종 이상의 RNA 서열, 바람직하게는 샘플내 2종 이상의 RNA 서열의 발현 수준 측정 단계로서, 상기 RNA 서열 및 RNA 서열들은, 서열번호 1 - 285로 표시된 서열들로부터, 또는 서열번호 1 - 285로 표시된 서열들 중 하나와 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 보다 바람직하게는 99.6% 이상의 또는 99.7% 이상의 동일성을 가지는 서열들로부터 선택되는, 1종 이상의 핵산 서열 및 2종 이상의 핵산 서열에 대한 각각의 전사 산물인 단계 및
(iii) (ii)에서 확인된 RNA 서열(들)의 발현 수준과 기준 발현 수준을 비교하는 단계를 포함할 수 있으며; 분석할 RNA의 발현 수준이 건강한 발현 수준에 비해 차이가 있는 측정 결과는, (상기 측정한 바와 같이) 대장암의 진단 또는 예후 예측과 연관시킬 수 있거나; 또는
(i) 분석할 샘플로부터 mRNA를 추출하는 단계,
(ii) 분석할 샘플로부터 mRNA를 검출 및 정량하는 단계,
(iii) 분석할 샘플에서의 mRNA 발현량을 기준 mRNA 양과 비교하는 단계를 포함할 수 있으며, 분석할 샘플에서 발현되는 mRNA의 양이 기준 mRNA의 양과 차이가 있는 측정 결과는, 대장암의 진단 또는 예후 예측과 연관시킬 수 있다 (기준 mRNA의 양 대비 분석할 샘플에서의 mRNA의 양 차이는 발현, 과다 발현 또는 저발현과는 무관함).
본 발명의 방법에 대한 일 구현예에서, mRNA의 DNA 카피들을 준비하고, DNA 카피들을 혼성화가능한 소정의 조건에서 하나 이상의 프로브 및/또는 하나 이상의 프라이머와 접촉시키고, 상기 DNA 카피에 대한 혼성화 유무를 검출한다.
또한, 검출하는 발현 산물은 또한 전술한 하나 이상의 전사체의 번역 산물인 폴리펩타이드일 수 있다. 이 경우, 발현되는 폴리펩타이드는 상기 폴리펩타이드의 하나 이상의 특이적인 결합 파트너, 구체적으로 항체, 항체 유사체 또는 앱타머와 접촉시킴으로써 검출한다. 결합 파트너는 바람직하게는 항체, 예컨대, 고도로 정제한 단일클론 항체 또는 다클론 항체, 항체 유사체, 예를 들어, 경쟁 특성을 가진 친화성 단백질 (nanofitinTM)이다.
다클론 항체는 적절한 면역원으로 동물을 면역화한 다음, 상기 동물의 혈청을 수집하여 다른 혈청 구성성분들로부터 상기 항체를 분리하므로써, 특히 항체에 의해 특이적으로 인지되는 항원이 결합된 컬럼에서의 친화성 크로마토그래피에 의해, 정제된 형태로 원하는 항체를 회수함으로써 수득할 수 있다.
단일클론 항체는 일반 원칙이 아래에 요약 기술된 하이브리도마 기법을 이용하여 수득할 수 있다.
먼저, 동물, 일반적으로 마우스를 적정 면역원으로 면역화하면, 상기 마우스의 B 림프구는 이 항원에 대한 항체를 생산할 수 있다. 이들 항체를 생산하는 림프구를 "불멸" 골수종 세포 (예, 뮤라인)와 융합하여, 하이브리도마를 만든다. 특정 항체를 생산할 수 있으며 무한정으로 증폭할 수 있는 세포를, 수득되는 혼성 세포 혼합물로부터 선별한다. 각 하이브리도마는 클론 형태로 증폭하며, 각각의 클론은, 단백질에 대한 인지 특성을 예를 들어, ELISA, 1차원 또는 2차원 웨스턴 블롯팅, 면역형광 또는 바이오센서를 이용함으로써 검사할 수 있는, 단일클론 항체를 생산한다. 이렇게 선별한 단일클론 항체를 이후 특히 전술한 친화성 크로마토그래피 기법에 따라 정제한다.
또한, 단일클론 항체는 당해 기술 분야의 당업자에게 잘 알려진 기법들을 이용하여 유전자 조직에 의해 수득되는 재조합 항체일 수 있다.
Nanofitins™은, 항체처럼, 생물 타겟에 결합할 수 있어, 이를 검출, 이를 포획 또는 유기체내에서 매우 단순하게 이를 타겟팅할 수 있는, 소형 단백질이다. 이는, 특히 항체 유사체로 제시된다.
앱타머는 특이 리간드에 결합할 수 있는 합성 올리고뉴클레오티드이다.
또한, 본 발명은, 대장암의 시험관내 진단 또는 예후 예측용 분자 마커로서, 분리된 1종 이상의 핵산 서열의 용도에 관한 것으로, 상기 핵산 서열은
(i) 서열번호 1 - 285의 서열들로부터 선택되는 1종 이상의 DNA 서열, 또는
(ii) 서열번호 1 - 285의 서열들로부터 선택되는 서열과 상보적인 1종 이상의 DNA 서열, 또는
(iii) 상기 (i) 및 (ii)에 따른 서열과 99% 이상 동일성, 바람직하게는 99.5% 이상의 동일성, 더 바람직하게는 99.6% 이상 또는 99.7% 이상의 동일성을 나타내는 1종 이상의 DNA 서열, 또는
(iv) 상기 (i)에 따른 서열들로부터 선택되는 서열의 전사 산물인, 1종 이상의 RNA 서열, 또는
(v) 상기 (i)에 따른 서열과 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 더 바람직하게는 99.6% 이상 또는 99.7% 이상의 동일성을 나타내는 서열들로부터 선택되는 서열의 전사 산물인, 1종 이상의 RNA 서열로 구성되는 것을 특징으로 한다.
일 구현예에서, 하기로 구성되는 2종 이상의 핵산이 이용된다:
(i) 서열번호 1 - 285의 서열로부터 선택되는, 바람직하게는 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 표시된 서열들로부터 선택되는, 특히 서열번호 2, 3 및 8의 서열들로부터 선택되는, 2종 이상의 DNA 서열, 또는
(ii) 서열번호 1 - 285의 서열로부터 선택되는, 바람직하게는 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 표시된 서열들로부터 선택되는, 특히 서열번호 2, 3 및 8의 서열들로부터 선택되는, 2종 이상의 서열에 각각 상보적인, 2종 이상의 DNA 서열, 또는
(iii) (i) 및 (ii)에 따른 2종의 서열과 99% 이상 동일성, 바람직하게는 99.5% 이상의 동일성, 더 바람직하게는 99.6% 이상 또는 99.7% 이상의 동일성을 각각 나타내는 2종 이상의 DNA 서열, 또는
(iv) (i)에 따른 서열들로부터 선택되는 2종 서열에 대한 각각의 전사 산물인, 2종 이상의 RNA 서열, 또는
(v) (i)에 따른 서열들과 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 더 바람직하게는 99.6% 이상 또는 99.7% 이상의 동일성을 나타내는 2종의 서열들에 대한 전사 산물인, 2종 이상의 RNA 서열.
또한, 본 발명은, 서열번호 1 - 285로 표시된 서열들로부터, 또는 서열번호 1 - 285로 표시되는 핵산 서열들과 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 더 바람직하게는 99.6% 이상 또는 99.7% 이상의 동일성을 나타내는 서열들로부터 선택되는 1종 이상의 핵산 서열의 1종 이상의 발현 산물에 대한 특이적인 결합 파트너 1종 이상, 및 서열번호 1 - 285로 표시된 핵산 서열, 또는 서열번호 1 - 285로 표시된 핵산 서열들과 99% 이상의 동일성, 바람직하게는 서열번호 1 - 285로 표시된 서열들 중 하나와 99.5% 이상의 동일성, 더 바람직하게는 99.6% 이상 또는 99.7% 이상의 동일성을 나타내는 핵산 서열의 발현 산물에 대한 특이적인 결합 파트너 285종 이하를 포함하는, 환자에서 취득한 생물학적 샘플에서 대장암을 시험관내 진단 또는 예후를 예측하기 위한 키트에 관한 것이다.
일 구현예에서, 키트는, 서열번호 1 - 285로 표시된 서열들로부터 선택되는, 또는 서열번호 1 - 285로 표시된 서열들 중 하나와 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 더 바람직하게는 99.6% 이상 또는 99.7% 이상의 동일성을 나타내는 서열들로부터 선택되는 2종 이상의 핵산 서열의 2종 이상의 발현 산물에 대한 각각의 특이적인 결합 파트너 2종 이상, 및 서열번호 1 - 285로 표시된 핵산 서열, 또는 서열번호 1 - 285로 표시된 핵산 서열들과 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 더 바람직하게는 99.6% 이상 또는 99.7% 이상의 동일성을 나타내는 핵산 서열의 발현 산물에 대한 특이적인 결합 파트너 285종 이하를 포함한다.
예를 들어, 키트는, 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 표시된 서열들, 또는 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 표시된 서열과 99% 이상의 동일성을 나타내는 서열들의 그룹으로부터 선택되는 2종 이상의 핵산 서열에 대한 발현 산물 각각의 특이적인 결합 파트너 2종 이상을 포함한다.
특히, 키트는, 서열번호 2, 3 및 8로 표시된 핵산 서열들, 또는 서열번호 2, 3 및 8로 표시된 서열과 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 더 바람직하게는 99.6% 이상 또는 99.7% 이상의 동일성을 나타내는 서열들에 대한 발현 산물 각각의 특이적인 결합 파트너 2종 또는 3종을 포함한다.
발현 산물에 대한 적어도 특이적인 결합 파트너는 상기 제시된 정의에 해당된다.
또한, 본 발명은, 일련의 생물학적 샘플들을 수득하는 단계, 및 상기 일련의 생물학적 샘플에서 1종 이상의 핵산 서열의 1종 이상의 발현 산물을 검출하는 단계를 포함하며, 상기 핵산 서열이 서열번호 1 - 285로 표시된 서열들로부터, 또는 서열번호 1 - 285로 표시된 서열들 중 하나와 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 보다 바람직하게는 99.6% 이상의 또는 99.7% 이상의 동일성을 나타내는 서열들 중에서 선택되는 것인, 대장암의 치료 효과 및/또는 예후를 평가하는 방법에 관한 것이다.
일 구현예에서, 2종 이상의 핵산 서열에 대한 2종 이상의 발현 산물을 검출하며, 상기 2종의 핵산 서열은 서열번호 1 - 285로 표시된 서열들로부터 선택되거나, 또는 서열번호 1 - 285로 표시된 서열들과 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 보다 바람직하게는 99.6% 이상의 또는 99.7% 이상의 동일성을 나타내는 서열들로부터 선택된다.
본 발명의 다른 구현예에서, 1종 이상의 핵산 서열, 바람직하게는 2종 이상의 핵산 서열 또는 3종의 핵산 서열의 발현 산물을 검출하며, 상기 핵산 서열은 서열번호 2, 3 및 8로 표시된 서열들의 그룹으로부터 선택되거나, 또는 서열번호 2, 3 및 8로 표시된 서열과 99% 이상의 동일성, 바람직하게는 99.5% 이상의 동일성, 보다 바람직하게는 99.6% 이상의 또는 99.7% 이상의 동일성을 나타내는 서열들로부터 선택된다.
용어 "생물학적 샘플"은 조직, 체액, 상기 조직과 체액의 구성 성분, 예를 들어 세포 또는 세포자살체 (apoptotic body) 및 특히 엑소좀 (exosome) 및 미세소포를 포함하는 배출된 소포 (excreted vesicle)를 의미하는 것으로 의도된다. 예를 들어, 생물학적 샘플은 대장암을 앓고 있는 것으로 추정되는 환자에서 사전에 수행된 대장 생검으로부터 유래되거나, 또는 전이 상태인 환자에서 대장 이외의 장기에서 수행된 생검으로부터 유래될 수 있다. 2번째의 경우, 핵산 (분자 마커)의 발현 변화가 대장 장기에 특이적인 경우, 원발성 암, 즉 대장암으로 다시 돌아갈 수 있다. 또한, 생물학적 샘플은 생물 체액, 예컨대 혈액 또는 혈액 분획 (혈청, 혈장), 뇨, 타액, 뇌척수액, 림프액, 모유, 정액 및 상기 체액들의 구성성분들, 특히 상기 정의된 배출된 소포일 수 있다. 예를 들어, 상피 세포로부터 발생되는 엑소좀 또는 미세소포에서 대장 조직에 특이적인 전사체의 검출은, 장기 수준에서 샘플을 취하지 않고도 원발성 암 또는 전이가 존재한다는 신호이다.
도 1 및 2는 HERV 서열 세트에 대한 대장암에서 관찰되는 차별적인 발현을 나타낸 것이다. 보다 구체적으로, 도 1 (클러스터링)은 대조군 조직 전체와 비교하여 대장암 관련 발현 굴성 (expression tropism)을 가지는 HERV 인자들을 평가 방식으로 그룹핑한 것이고, 도 2는 정상 대장과 종양 대장 간에 HERV 인자들의 발현에 대한 통계적인 차이를 나타낸 것이다.
도 3과 4는 2가지 생물 체액; 뇨와 혈청에서의 HERV 서열 검출을 나타낸 것이다.
도 5는 28개의 대장 종양과 18개의 건강한 대장 조직에서의 서열번호 2, 3, 및 8의 서열들에 대한 정량적인 RT-PCR로 수득한 발현 결과를 나타낸 것으로, 특히 결장직장 종양 샘플에서 검출 건수를 높이기 위한 이들의 조합의 유용성을 나타낸 것이다.
실시예:
실시예 1: 대장암에서 차별적인 발현을 나타내는 HERV 서열들의 동정
방법:
대장암에서 차별적인 발현을 보이는 HERV 서열들의 동정은, 본 발명자가 설계하고 Affymetrix에서 하청 계약하여 제작한, HERV-V2라고 하는 GeneChip 포맷의 고-밀도 DNA 칩의 설계 및 사용을 토대로 한다. 이 칩은 인간 게놈에서 구별되는 HERV 서열들에 해당하는 프로브를 함유하고 있다. 이들 서열은 기능성 영역들 (LTR, gag, pol 및 env)로 절단한 프로토타입의 기준 세트들을 이용하여 동정하고, 전체 인간 게놈 규모 (NCBI 36/hg18)에서 유사성 검색을 이용함으로써, 구별되는 HERV 유전자 좌 10,035곳을 동정하고, 주해를 단 후, 마지막으로 HERVgDB3이라고 하는 데이타은행에서 그룹핑하였다.
칩 구성의 일부인 프로브는 HERVgDB3을 토대로 정하고, 제작 프로세스에서 원하지 않은 타겟과 혼성할 위험성이 높은 프로브를 제외할 목적으로 혼성화 특이성 기준을 적용하여 선별하였다. 이를 위해, HERVgDB3 서열들을 먼저 중첩성 뉴클레오티드 (25mer) 25개로 구성된 세트들로 분할하여, 후보 프로브 세트를 구성하였다. 그런 다음, KASH 알고리즘을 이용하여 인간 게놈 전체에 정렬을 수행함으로써, 각 후보 프로브에 대해 비특이적인 혼성화 위험성을 평가하였다 (2). 실험 스코어는 정렬에서 에러의 수, 타입 및 위치에 대한 영향과 더불어, 혼성화 결과를 표시한다. 이 스코어 값은 타겟/프로브 혼성화 가능성과 연관된다. 전체 인간 게놈에 대한 후보 프로브들의 모든 혼성화 가능성에 대한 지식으로 이의 포획 특이성을 평가할 수 있다. 우수한 포획 친화성을 나타내는 후보 프로브들을 유지시킨 다음, "프로브 세트"로 그룹핑하고, 마지막으로 HERV-V2 칩에서 합성하였다.
HERV-V2 고-밀도 칩을 이용하여 분석한 샘플들은 종양에서 추출한 RNA와 이들 종양에 인접한 건강한 조직에서 추출한 RNA이다. 분석한 조직은 대장, 유방, 난소, 자궁, 전립선, 폐, 고환 및 대조군으로서 태반이다. 태반의 경우, 오직 건강한 조직만 사용하였다. 각 샘플에 대해, WTO로 알려져 있는 증폭 프로토콜을 이용한 cDNA 합성에 RNA 50 ng을 사용하였다. WTO 증폭 원리는 다음과 같다: 랜덤 프라이머와 또한 RNA 전사체의 3' 말단을 타겟팅하는 프라이머를, 역전사 단계 전에 부가한 다음, SPIA로 표시하는 선형의 단일 가닥 증폭을 수행한다. 그런 다음, cDNA를 분석하고, 특정화한 다음 정제하고, 2 ㎍을 단편화한 후 말단 트랜스퍼라제 효소 작용을 통해 3' 말단에 바이오틴을 표지하였다. 이렇게 제조한 타겟 산물을 대조군 올리고뉴클레오티드와 혼합한 다음, Affymetrix 사에서 권고한 프로토콜에 따라 혼성화를 수행한다. 그런 후, 칩을 가시화하고, 판독하여 이의 형광 이미지를 수득한다. 표준 대조군에 기반한 품질 관리를 수행하고, 인디케이터 (MAD, MAD-Med plots, RLE) 세트를 제공하여, 통계 분석에 부합되지 않는 칩은 제외시킨다.
칩 분석은 먼저 트립토판 프로브의 신호 세기를 기반으로 백그라운드 노이즈를 보정함으로써 데이타를 전처리한 다음, 분위법 (quantile method)을 기초로 RMA 표준화 (RMA normalization)를 수행한다 (3). 그런 다음, 발현 배치들과 연계된 효과들을, 관찰되는 발현 차이가 생물학적으로 기원한 것이지 기술적인 것은 아님을 보증하기 위해, COMBAT 방법 (4)을 적용하여 이중 보정 (double correction)을 수행한다. 이 단계에서, 데이타의 예비 분석은 유클리드 분할 (클러스터링)에 의해 데이타를 함께 그룹핑하는 툴을 이용하여 수행하며, 마지막으로, SAM 절차 (5)를 이용한 다음 위 양성율 (6)을 통해 보정함으로써 통계학적으로 분석하고, 조직의 정상 상태와 종양 상태 간의 차별적인 차이를 나타내는 서열들을 검색하기 위해, 26 이하의 값은 제외한다.
결과:
본 방법을 이용하여 HERV-V2 DNA 칩을 분석함으로써 수득한 데이타를 가공하여, 정상 대장과 종양 대장 간에 통계학적으로 유의한 발현 차이를 보이는 "프로브 세트"의 세트를 동정할 수 있었다. 클러스터링 결과와, 또한 대조군 샘플들에서의 차별적인 발현 검색으로, 또한, 차별적인 발현이 종양 대장과 특이적으로 관련있는 HERV 인자들을 확인하였다.
종양 대장에서 차별적인 발현을 나타내는 HERV 인자들의 뉴클레오티드 서열들은 서열번호 1 - 285로 표시하며, 각 서열의 염색체 위치는 NCBI reference 36/hg18에 제공되며, "타겟 조직" 정보 (크로스)는 (대조군 조직들에서의 비교와 비교하여) 정상 대장과 종양 대장을 비교하였을 때 오직 차별적인 발현이 관찰된 인자들을 가르킨다. 정상 상태와 종양 상태 간의 발현 비율을 나타내는 값도 또한 제공하며, 단지 제시한 대상 서열들을 순서대로 열거하기 위해 이용한다.
실시예 2: 생물 체액에서의 HERV 서열 검출
원리:
본 발명자들은, HERV 서열들을 생물 체액에서 검출하여, 특히 원발성 장기의 원격 검출을 통해 대장암을 특정화할 수 있다. 실험은 여러 개체들로부터 기원한 뇨 샘플 20종과 혈청 샘플 38종을 대상으로 수행하였다.
혈청과 뇨를 하기 조건으로 원심분리하였다:
혈청: 500 g에서, 10분간 4℃. 상층액을 회수하여, 다시 4℃에서 20분 동안 16,500 g로 다시 원심분리하였다. 이 2차 원심분리의 상층액은 세포는 제거되었지만, 엑소좀, 미세소포, 핵산 및 단백질은 포함하고 있으며, 이를 칩에서 분석하였다. 이 칩은 전술한 방식으로 사용된 HERV-V2 칩이다.
뇨: 취득한 후, 4℃에서 4분간 800 g로 원심분리한다. RNA protecr cell reagent™으로 펠렛을 회수하였다. 그런 후, 5분간 5000 g로 원심분리한 다음 펠렛에 세포용혈 완충제를 첨가하였다. 칩은 전술한 방식으로 사용된 HERV-V2 칩이다.
결과:
상기 표에 열거된 서열들에 대응되는 발현 신호 등의 파지티브 신호들이, 도 3 및 4에 예시된 바와 같이 혈청 상층액과 뇨에서 기원한 세포 펠렛 둘다에서 다수 검출되었다. 이는, 생물 체액, 특히 혈청 및 뇨가 HERV 서열을 검출하기 위한 유용한 생물 물질 소스이라는 것을 검증해준다. 양성 임계값 (positivity threshold) 약 26, 즉, 64는 통상적으로 허용된다.
실시예 3: 결장직장암을 검출하기 위해 HERV 서열 2 및 3종을 조합하는 경우의 유용성 입증
방법:
28개의 대장 종양 (CT1, CT2, CT3, CT65, CT94, CC1, CC2, CC3, CC4, CC5, CC6, CC7, CC8, CC9, CC10, 549T, 551T, 553T, 556T, 558T, 559T, 560T, 561T, 601T, 602T, 604T, 607T 및 615T) 18개의 건강한 대장 조직 (CN1, CN2, CN3, CN64, CN93, 549N, 551N, 553N, 556N, 558N, 559N, 560N, 561N, 601N, 602N, 604N, 607N 및 615N)에서 RNA들을 추출하고, 이를 사용하여, 2종 또는 3종의 HERV 서열들의 발현 결과를 조합하면 결장직장 종양 샘플에서 검출 건수를 높일 수 있다는 것을 입증하였다.
서열번호 2의 1723-1824 영역, 서열번호 3의 1540-1665 영역 및 서열번호 8의 1684-1923 영역에 대응되는 정량적인 RT-PCR 증폭을, 본 실험의 샘플 46종 전체에 대해 수행하였다. HERV 서열의 발현 결과를 delta Ct 방법을 이용하여 가공하고, GAPDH 하우스키핑 유전자의 발현 결과를 이용하여 표준화하였다. 그 결과를 도 5에 나타낸다.
결과:
서열번호 2의 1723-1824 영역에 대한 정량적인 RT-PCR 증폭은 11개의 대장 종양 샘플들 (CT3, CT94, CC1, CC2, 558T, 559T, 560T, 561T, 602T, 604T 및 607T)에서 양성이다. 건강한 대장 조직 샘플들에서는 이 영역에 대한 검출은 관찰되지 않는다.
서열번호 3의 1540-1665 영역에 대한 정량적인 RT-PCR 증폭은 6개의 대장 종양 샘플들 (CT1, CT3, CT94, CC5, CC8 및 CC10)에서 양성이다. 건강한 대장 조직 샘플들에서는 이 영역에 대한 검출은 관찰되지 않는다.
서열번호 8의 1684-1923 영역에 대한 정량적인 RT-PCR 증폭은 4개의 대장 종양 샘플들 (CT3, CC2, CC6 및 CC10)에서 양성이다. 건강한 대장 조직 샘플들에서는 이 영역에 대한 검출은 관찰되지 않는다.
합체하는 방식으로, 서열번호 2의 1723-1824 영역과 서열번호 3의 1540-1665 영역을 검출하면, 15개의 대장 종양 샘플들 (CT1, CT3, CT94, CC1, CC2, CC5, CC8, CC10, 558T, 559T, 560T, 561T, 602T, 604T 및 607T)을 커버할 수 있다는 점을 고려해볼때, 즉 이러한 2종의 HERV 서열들의 조합은 이들 동일 HERV 서열들을 단독으로 이용하는 경우에 비해 민감성이 증가된다.
합체하는 방식으로, 서열번호 2의 1723-1824 영역과 서열번호 8의 1684-1923 영역을 검출하면, 13개의 대장 종양 샘플들 (CT3, CT94, CC1, CC2, CC6, CC10, 558T, 559T, 560T, 561T, 602T, 604T 및 607T)을 커버할 수 있다는 점을 고려해볼때, 즉 이러한 2종의 HERV 서열들의 조합은 이들 동일 HERV 서열들을 단독으로 이용하는 경우에 비해 민감성이 증가된다.
합체하는 방식으로, 서열번호 3의 1540-1665 영역과 서열번호 8의 1684-1923 영역을 검출하면, 8개의 대장 종양 샘플들 (CT1, CT3, CT93, CC2, CC5, CC6, CC8 및 CC10)을 커버할 수 있다는 점을 고려해볼때, 즉 이러한 2종의 HERV 서열들의 조합은 이들 동일 HERV 서열들을 단독으로 이용하는 경우에 비해 민감성이 증가된다.
마지막으로, 합체하는 방식으로, 서열번호 2의 1723-1824 영역, 서열번호 3의 1540-1665 영역 및 서열번호 8의 1684-1923 영역을 검출하면, 16개의 대장 종양 샘플들 (CT1, CT3, CT94, CC1, CC2, CC5, CC6, CC8, CC10, 558T, 559T, 560T, 561T, 602T, 604T 및 607T)을 커버할 수 있다는 점을 고려해볼때, 즉 이러한 3종의 HERV 서열들의 조합은 이들 동일 HERV 서열들을 단독으로 또는 한쌍으로 조합하여 이용하는 경우에 비해 민감성이 증가된다.
SEQUENCE LISTING <110> bioMerieux <120> Procede pour le diagnostic et le pronostic in vitro du cancer du colon <130> ENDOCOL PCT <150> FR1162049 <151> 2011-12-20 <160> 285 <170> PatentIn version 3.5 <210> 1 <211> 7574 <212> DNA <213> Homo sapiens <400> 1 tgtggtcaga attcttacac aagagccagg accgcaccct gtagcctttc tgtgcaaaca 60 acttgacctt actgttttag cctagccctc atgtctgcct gcagcggctg ctgctgcttt 120 aatactttta gaggccctca aaatccccaa ctatgctcaa ctcactgtac agttctcata 180 acttccaaaa tctattttct tcttcatacc tgacgcatat actttctgct tcccggctcc 240 ttcagctata ctcactcttt tctgagtctc ccacaattat cattgttcct ggcccagact 300 tcaatccggc ctcccacatt attcctgata ccacacctga cccccatgac tgtatctctc 360 tgatccacct gacattcacc ccatttcccc aaatttcctt ctttcctctt cctcaccctg 420 atcatgcttg atttattgat ggcggttcca ccaggcctaa tcgccacaca ccagcaaagg 480 caggttatgc tatagtacaa gccactagcc tgcctcttag aacctctcat ttcttttcca 540 tcgtggaaat ctaccctcaa ggaaataact tctcagtgtt ccatctgcta ttctactact 600 cctcagggat tattcaggcc ccctcccttc cctacacatc aagctcgagg atttgccccc 660 acccaggact ggcaaattag ctttactcaa catgcccaag tcaggaaact aaaatacccc 720 ttagtctaaa tagacacttc cactgaataa gtaaaggcct ttcgtacagg gtctgagaag 780 gccacggcag tcatttattc ccttctgtca gacataattc ctcagtttag ccttcccacc 840 tcaatacagt ctgataacag acgagccttt attagtcaaa tcagccaagc agtttttcag 900 gctcttagta ttcagtgaaa cctttatatc ccttaaggtc ctccatcttc aagaaaagta 960 gaatggacta aaggtctttt aaaaacacgc ctcaccaagc tcagccacca acttaaaaag 1020 gactggacaa tacttctacc actttccctt ctcagaattc aggcctgtca gaatgctaca 1080 gggtacagcc catttaagct cctgtataga cgctcctttt tattaggccc cagtctcatt 1140 ccagacacca gaccaactta gactgtgccc ccctcccaaa aaaaacttgt catccctact 1200 attttctgtc tagtcatact cctattacca ttctcaacta ctcatacatg ccctgctctt 1260 ctttacactg ccggtttaca ctgtttctcc aagccatcac agctgatatc tcctggtgct 1320 atccccaaac tgccactctt aactcttgaa gtaaataaat aatctttgct ggcaggactc 1380 tgctgaatct ccttaggcac tctctaatca gatatcctag gtcctcccaa ttcttagacc 1440 ttttatacct gtttttctcc ttctgttatt ccatttagtt tctcaattca tacaaaaccg 1500 tatccaggcc atcaccaatc attctatatg acaaatgttt cttctaacat ccccacaata 1560 tcacccctta ccacaagacc tcccttcagc ttaatctctc ccactctagg ttcccacgct 1620 gcccctaatc ccacttgaag cagccctgag aaacatcgcc cattctctct ccctaccacc 1680 cctcaaaaat tttcaccacc ccaacacttc aacactattt tgttttattt ttcttattaa 1740 tataagaagg caggaatgtc aggcctttga gcccaatcca agacatcgca tcccctgtga 1800 cttgcacgta tatgcccaga tggcctgaag taactgaaga atcacaaaag aagtgaaaag 1860 gccctaccct gtgttaactg atgtcattcc accattgtga tttgttcctg ccccacctta 1920 actgaatgat taaccctgtg aatttccttc tcctggctca gaagctcccc cactgagcac 1980 cttgtgaccc ccgcccctgc ccaccagaga acaaccccct tttactgtaa ttttccatta 2040 ccttcccaaa tcctataaaa tggcctcacc cctatctccc tttgctgact ctcttttcgg 2100 actcagccca cctgcacaca ggtgattaaa agctttattg ctcacacaaa gcctgtttgg 2160 tggtctcttc acacagatgc gcatgaaaat aaggatgccc acattcatca tttctattca 2220 acatagtacc agaagtccta gccagagcaa caagacaaga gaaagagata aaaggcatcc 2280 aaattgaaga gaaaaacgtc aaaacgttcc tgtttgcaga caacatgatc ttagagacgg 2340 aaaaccctaa agactccacc aaaacctgtt ataattaata aacaaattta gtaaagtagc 2400 aggatacaaa atcaacttac gataatcagt agtattttta gatggcatta ttaagctatc 2460 tttaaaaatc aagaaaaaaa tctcatttac agtacaatag cacaaaaaat aagattccta 2520 agaataaacc taaccaagaa ggtgaaaaat atctacaaca aaaactataa aacattgatg 2580 aaaaatggaa gaggacacaa ataaatagaa ggatacagaa aaataccccc atgttcattg 2640 atttaaagaa ttggaattgt taaagtgtcc atactaccca aaacaatcta gagattcaat 2700 gtaatagcta tcaaaatatc catgatattc ttcatagaaa tagaaagaaa aatcctaaaa 2760 tgtgtatgga accacaaaag accccaaata gccaaatcaa tcttaagcaa acagaaccaa 2820 gctagaggga tcacatacct ggcttcaaaa tgtactacaa agctgtaata accaaaatag 2880 catggtagtg gcataaaaac aggcatatac accaagggac tagaatacag ttagaaataa 2940 atccacagac ttacaaccaa ctgattttca acatagatgc caaaaataca cgttggggaa 3000 agggcaatca cttcaataaa tagtgtggag gaaactgagt atgtacatgc agacatggaa 3060 ctagacccct atctctcacc atatgcaaaa attaactcaa aatggattaa aacttaaata 3120 taatgtcagg tctctgagcc caagccaagc catcgcatcc cctgtgactt gcatgtatac 3180 gcccagatgg cctgacgtaa ctgaagaatc acaaaagaag tgaaaaggtc ctgccccgcc 3240 ttaactgatg acattccacc attgtgattt gttcctgccc caccttaact gattaaccct 3300 gtgaatcatt ctcctggctc agaagctccc caagtgagca ccttgtggcc ccagcccctg 3360 cccaccagag aacaaccccc tttgactgta attttccttt acctacccaa atcctataaa 3420 acagccccac ccttaactcc ctttgctgac tctcttttcg gactcagccc acctgtaccc 3480 aggtgaaata aacagccatg ttgctcacac aaagcctgtt tggtgatctc ttcacacgga 3540 cgcgcatgaa atttggagac atgactcgga tcgggggacc tcccttggga gatcaatacc 3600 ctgtcctctt gttctttgct ccatgagaaa gatccaccaa tgacctcagg tcctcagaac 3660 aaccagcctg agaaacatct caccaatttc aaatccggta agcagcctct ttttactctc 3720 ttctccaacc tccctcacta tccctcaacc tctttctcct ttcaatcttg gccccacatt 3780 tctatctctc ccttctctta atttcaattc ctttcaattc ttttggtaga gacaaaggag 3840 acacgtttta tccgtggacc caaaactctg gcaccggtca cggactggga aggcagcctt 3900 cccttggtgt ttaatcattg cagggacacc tctctgatta ttcacccacg tttcaaaggt 3960 gtcagaccat gcagggacac ctgccttggt ccttcaccct tagcagcaag tcccattttt 4020 ctggggcagg ggcaagtacc cctcaacccc ttctccttca cccttagcag caagtcccgc 4080 tttcctgggg caggggcaag tacccctcaa ccccttctcc ttcaccctta gtggcaagtc 4140 ccgctttcct agggggcaag aaccccccaa tcacttattt ccacacccca acctcttatc 4200 tctgcacccc aatcccttat ttctgcaccc tgacctctta tctctgtgcc ccaatccctt 4260 atttccacgc cccaacctct tatatctctg caccccaatc ccttatttct gcaccctgat 4320 ctatctctgt gccccaaccc cttttctgga aggtgagaac acctgaacca cttccctcca 4380 tttctctact ctctcttttc tctaggtttg cttccttcac tatgggcaac cttccaccct 4440 ccattcctcc ttctactccc ttggcctgtg ttctcaaaaa cttaaaacct cttcaactca 4500 cacctgacct aaaacttaaa cgccttattt tcttctgcaa tgctgcttga ccccaataca 4560 aactcaacag tagttccaaa tagccagaaa atggcacttt gaatttttcc atcctgcaaa 4620 atctaaataa ttcttgtcgt aaaataggca aacggtctga ggtgcctgac gtccaggcat 4680 tcttttacac atcagtccct tcctagtctc tgtgcccagt gcaactcgtc ccaaatcttc 4740 cttctttccc tcccacctgt cccctcagta ccaaccccaa gcgtcgctga gtctttctaa 4800 tcttcctttt ctacagaccc atctgacctc tcccttcttc cccaggctgc tcctcgccag 4860 gccgagctag gtcccaattc ttcctcagcc tctgctcctc caccctataa tctttttacc 4920 acctctcccc tcctcacacc tggtctggct cacagtttca ttccatgact agccctcctc 4980 cacctgccca gcaatttact cttaaaaagg tggctggagc taaaggcata gtcaaggtta 5040 atgctccttt ttctttatcc caaatcagaa gtgtttaggc tctgtttcat caaatataaa 5100 aatccagccc agttcatggc tcatttggca gcaaccctga gacactttac agtcttagac 5160 cctaaaaggt caaaaggccg tcttattctc aaaatacatt ttattaccca atctgctcct 5220 gacattaaat aaaactccaa aaattaaatt ctggccctca aaccccacaa caggatttaa 5280 ttaacctcgc cttcaaggtg tacaataata gaaaaaagtt gcaattcctt gcctccactg 5340 tgagacaaac cccagccaca tctccagcac acaagaactt ccaaacgcct gaactgcagt 5400 ggccacgcgt tcctccagaa cctcctccca taggagcttg cttcgtgtgc cagaaatctg 5460 gccactgggc caaggaatgc ccgcagcccg ggattcctcc taatccacgt cccatctctg 5520 tgggacccca ctgaaaatcg gactgttcaa ctcacctgga agccactccc agagcccctg 5580 gaacactggc caaaggctct ctgactgact ccttcccaga tcttcttggc ttagcagctg 5640 aagactgaca ctgcccgatc acctcagaag cacccttgac catcacggat gccgagctat 5700 gggtaactct cacagtggaa ggtaagcccg tccccttctt aatcaatacg gaggctaccc 5760 acgccacatt accttctttt caagggcctg tttcccttgc ctccataact gttgtgggta 5820 ttgacggcca ggcttctaaa cctcttaaaa ctccccaact ctggtgccaa cttagacaat 5880 actcttttaa gcactccttt ttagttatcc ccatctgccc agttccctta ttaggctgag 5940 acactttaac taaattatct gcttccctga ctattcctgg actacagctg tatctcattg 6000 ccacccttct tcccaatcca aagcctcctt tgtgtcctcc tcttgtatac ccccacctta 6060 acccacaagt ataagatatc tctactccct ccttgacgac cgatcatgca ccccttacca 6120 tctcattaaa acctaatcac ccttaccgca ctcaatgcca gtatcccatt ccgcagcacg 6180 ctttaaaaag attaaagcct gttatcattc gcctgttaca gcatggcctt ttaaacccta 6240 taaactctcc ttacaattcc cccatttttc ctgtcctaaa acgagacaag ccttacaagt 6300 tagttcagga tctgcacctt atcaaccaaa ttgttttgcc tatccacccc gtggtgccaa 6360 acccatatac tctcctatcc tcaatacctc cctctactac ccattattct gttctggatc 6420 tcagacatgc tttctttact attgctttgc acccttcatc ccagcctctc tttgccttca 6480 cttagactga ccctgacacc cattaggctc aacaaattac ctgggctgca ctgccacaag 6540 gcttcacaga cagcccccat tacttcagtg aagcccaaat ttcatcctca tctgttagtc 6600 atactcctgt tcaccgttct caactactca tacatgccct gctcttcttt acactgccgg 6660 tttacactgt ttctccaaga catcacagct gatatctcct ggtgctatcc ccaaactgcc 6720 actctaaact cttgaagtaa ataaataatc tttgctggca ggactctgct gaatctcctt 6780 aggcactctc taatcagata tcctaggtcc tcccaattct tagacctttt atacctgttt 6840 ttctccttct gttattccat ttagtttctc aattcataca aaaccgtatc caggccatca 6900 ccaatcattc tatatgacaa atgtttcttc ttacatcccc acaatatcac cctttaccac 6960 aagacctccc ttcagcttaa tctctcccac tctagattcc cacgctgccc ctaatcccac 7020 ttgaagcagc cctgagaaac atcgcccatt ctctctccct accacccctc aaaaattttc 7080 accaccccaa cacttcaaca ctattttgtt ttatttttct tattaatata agaaggcagg 7140 aatgtcaggc ctctgagccc aagccaagcc atcgcattcc ctgtgacttg cacgtatacg 7200 cccagatggc ctgaagtaac tgaagaatca caaaagaagt gaaaaggtcc tgccccacct 7260 taactgatga tattccacca ttgtgatttg ttcctgcccc accttaactg agtgattaac 7320 cctgtgaatt gttctcctgg ctcagaagct ccccaactga gcaccttgtg acccccaccc 7380 ctgcccacca gagaacaacc cccttttact gtaattttcc tttaccaacc caaatcctat 7440 aaaatggccc cacccctatc tcccttcgct gactctcttt ttggactcag cccgcctgca 7500 cccaggtgaa ataaacagcc atgttgctca aacaaagcct gtttggtggt ctcttcacac 7560 ggatgtgcat gaaa 7574 <210> 2 <211> 5846 <212> DNA <213> Homo sapiens <400> 2 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcat gtatacgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa tatgccctgc cccaccttaa 120 ctgatgacat tccaccattg tgatttgttc ctgccccacc ctaactgatc aatgtacttt 180 gtaatctccc ccacccttaa gaaggtcctt tgtaattctc cccacccttg agaatgtact 240 ttgtgagatc cacccctgcc caccagagaa caaccccctt tgactgtaat tttccattac 300 cttcccaaat cctataaaac ggccccaccc ctatctccct ttgctgactc tcttttcgga 360 ctcagcccgc ctgcacccag gtgaaataaa cagccatgtt gctcacacaa agcctgtttg 420 gtggtctctt cacatggacg cacatgaaat ttggtgccat gactcggatc gggggacctc 480 ccttgggaga tcaatcctcc gtcctcctgc tctttgctcc ctgagaaaga tccacctacg 540 acctcaggtc ctcagaccga cgagcccaag aaacatctca ccaatttcaa atctggtaag 600 cagcctcttt ttactctctt ctccaacttc cctcactatc cctcaaccac tttctccttt 660 caatcttggc actacacttc aatctctccc ttctcttaat ttcaattcct ttcattttct 720 ggtagagaca aaagagacac gttttatccg tggacccaaa actccggcgc tggtcacaga 780 ctgggaaggc agccttccct tggtgtttaa tcattgcagg gatgcctctc tgattataca 840 cccacgtttc aagggtgtca gaccacgcag ggacaactgc cttggtcctt cacccttagc 900 agcaagtccc gcttttctgg ggaaggggca agtaccccaa ccccttctct ccgtgtctct 960 accccttctc tgcttttccg gggacagggc aagtacccca accccttctc tccgtgtctc 1020 tactccttct ctgcttttct ggggacaggg caagtacccc aaccccttct ctccttgtct 1080 ctaccccttc tctgcttttc tggggcaggg gcaagtaccc ctcaacccct tctccttcac 1140 ccttagcggt aagtcccgct tttctagggg gcaggggcaa gtacccccca accccttctc 1200 cttcaccctt agtggcaagt cctgctttcc tggggcaggg gcaagtaccc cttaacccct 1260 tctccttcac ccttagcagc aagtcccact tttctagggg gcaagaaacc ccaaacccct 1320 tccctccgtg tctttacgct ctcttttctc tgggtttgct tccttcacta tgggcaacct 1380 tccatcctcc attcctcctt ctcccttagc ctgtgtgctc aagaacttaa aacctcttca 1440 actcacacct gacctaaaac ctaaatgcct cattttcttc tgcaacaccg cttggcccca 1500 atacaaactt gacaatggct ctaaatggcc agaaaatggc actttcgatt tctccatcct 1560 acaagaccta aataattttt gtcaaaaaat gggcaaatgg tctgaggtgc ctgatgtcca 1620 ggcattcttt tacacatccg tcccttccta gtctctgtgc ccagtgcaac tcgtcccaaa 1680 tcttccttct ttccctccca cctgtcccct cagtcccaac cccaggcgtt gctgagtgtg 1740 tctaatcttc cttttctaca aacccatctg acctctcccc tcctctccac gccaagctag 1800 gtcccaattc ttcctcaggc tccactcctc caccctgtaa tctttttatc acctcccctc 1860 ctcacacctg gtccggctta cagtttcgtt ccgtgactag ccctccccca cctgcccagc 1920 aatttactct taaaaaggtg gctggagcta aagacatagt caaggttaat gctccttttt 1980 ctttatccca aatcagaagc gtttaggctc tttttcatca aatataaaaa cccagcccag 2040 ttcatggctc gttcggcagc aaccctgaga cgctttacag ccctagaccc taaaaggtca 2100 aaaggccgtc ttattctcaa tatacatttt attacccaat ctgctcccga tattaaataa 2160 aactccaaaa attaaattcc ggccctcaaa ctccacaaca ggatttaatt aacctcgcct 2220 tcaaggtgta caataataaa aaaaaaaaag ttgcaattcc ttgcctccac tgtgagacaa 2280 accccagcca catctccagc aaacaagaac ttccaaacac ctgaaccgca gcagccaggc 2340 gttcctccag aacctcctcc cacaggagct tgctacaagt gccagaaatc tggccaccaa 2400 gccaagaaat gcctgcagcc caggattcct cctaagccgt gtcccatctg tgcgggaccc 2460 cattggaaat cagactgttc aactcacctg gcagcgactc ccagagaccc tggaactctg 2520 gcccaaggct ctctgactga ctccttccca gatcttctcg gcttagcggc tgaagactga 2580 cgctgcccaa tcacctcgga agccctgtag accatcacag acactgagct ttaggtaact 2640 ctcacagtgg agggtaagtc cgtccccttc ttaatcaata tggaggctcc ccactccaca 2700 ttacctactt ttcaagggcc tgtttccctt gcctccataa ctgctgtggg tattgacggc 2760 caggcttcta aacctcttaa aacttcccaa ctctagtgcc aacttagaca atactctttt 2820 acgcactcct ttttagttat ccccacctgc ccagttccct tattaggccg agacacttta 2880 actaaattat ctgcttccct gactactcct ggactacagc tgcatctcat tgccgccctt 2940 attcctaatc caaagcctcc tttgcgtcct cctcttgtat ccccccacct taacccacaa 3000 gtataagata cctctactcc ctccttggcg accgatcatg caccccttac catctcatta 3060 aaacctaatc acccttaccc cgctcaacac caatatccca tcccacagca tgctttaaaa 3120 ggattaaagc ctgttatcac ttgcctgcta cagcatgggc tcctaaaacc tataaactct 3180 ccttaccatt cccccatttt acctgtccta aaaccagaca agccttacaa gttagttcag 3240 aatctgcgcc ttatcaacca aatgttttgc ctatccaccc cgtggtgcca aacccgtata 3300 ctcttctatc ctcaatacct ccctctacta cccattattc tgttctggat ctcaaacatg 3360 ctttctttac tattcctttg cacccttcat cccagcctct ctttgccttc acttagactg 3420 accctgacac ccattaggct cagcaaatta cctgggctgt actgccgcaa ggcttcacag 3480 acagccccca ttacttcagt caagcccaaa tttcatcctc atctgttacc tatctcagca 3540 taattctcat aaaaacacag gtgctctccc tgctgatcgt gtccgattaa tctcccaaac 3600 ctcaatccct tacaaaagaa caactccttt ccttcctagg catggttagt gtggtcagaa 3660 ttcttacaca agagccagga ctgcaccctg tagcctttct gtccaaacaa cttgaccttc 3720 ctgttttagc ctagccatca tgtctgtgtg cagccgctgc cgctgcttta atactgttag 3780 aggccctcaa aatcacaaac tatgctcaac tcactctcta catttctcat aacttccaaa 3840 atctattttc ttcctcatac ctgacgcata tactttctgc tccccggctc cttcagctgt 3900 actcacactt tcttaagtcc cacaattacc attgttcctg gcctggactt caatctggcc 3960 tcccacatta ttcctgatac cacacctgac ctccatgact gtatctctct gatccacctg 4020 atattcaccc catatttcct tctttcctgt tcctcaccct gatcacgctt gatttattga 4080 tggaagttcc accaggccta atcgccacac accagcaaag gcaggttatg ctatagtaca 4140 agccactagc ccacctctca gaacctctca tttcctttcc atcgtggaaa tctatcctca 4200 aggaaataac ttctcagtgt tccatctgct attctactac tcctcaggga ttattcaggc 4260 cccctccctt ccctacacat caggctggag gatttgcccc acccaggact ggcaaattac 4320 ctttactcaa catgccctga ttcaggaaac taaaatacct cttagtctaa atagacactt 4380 tcactgaata aagtaaaggc ctttcctaca gggtctgaga aggccaccac agtcatttct 4440 tcccttctgt cagacacaat tcctcagttt agccttccca cctctataca gtctgataac 4500 agaccagcct ttattagtca aatcagccaa gcagtttttc aggctcttag tattcagtga 4560 aacctttata tcccttacgg tcctccttct tcaagaaaag tagaacggac taaaggtctt 4620 ttaaaaacac acctcaccaa gctcagccac cagcttaaaa aggactggac aatactttta 4680 ccactttccc ttctcagaaa tcaggcctgt cctcagaatg ctacaaggta catcccattt 4740 aagctcctgt atagacgctc ctttttatta ggccccagtc tcattccaga caccagacca 4800 acttagactg tgccccaaaa aacttgtcat ccctactatc ttctgtctag tcatactcct 4860 attcaccgtt ctcaactact catacatgcc ctgctcttgt ttacactgcc ggtttacact 4920 gtttctccaa gccatcacag ctgatatctc ctggtgctat ccccaaactg ccactcttaa 4980 ctcttgaagt aaataatctt tgctggcagg actatgctga atctccttag gcactctcta 5040 atcagatgtc ctaggtcctc ccaattctta gacatttaat acccattttt ctcctccttt 5100 tattcggacc ttgtatcttc catttagctt ctcaaatcat ccaaaaccgt atccaggcca 5160 tcaccaatca ttctatacga caaatgtttc ttctaacatc cccatgatat caccccttac 5220 cacaagacct cccttcagct taatctctcc cactctaggc tcccacgccg cccctaatcc 5280 cgcttgaagc agccctgaga aacatcgccc attatctctc cataccaccc cccaaaaatt 5340 ttcgctgccc caacacttca acactatttt gttttatttg tcttattaat ataagaaggc 5400 aggaatgtca ggcctctgag cccaggccag gccatcgcat cccctgtgac ttgcacgtat 5460 acatccagat ggcctaaagt aactgaagat ccacaaaaga agtaaaaaca gccttaactg 5520 atgacattcc aacattgtga tttgttcctg ccccacccta actgataaat gtactttgta 5580 atctccccca cccttaagaa ggtcctttgt aattctcccc acccttgaga gtgtactttg 5640 tgagatccac acctgcccac cagagaacaa accccctttg actgtaattt tccattacct 5700 tccctaatcc tataaaacgg ccccacccca tctccctttg ctgactctct tttcggactc 5760 agcccgcctg cacccaggtg aaataaacag ccttgttgct cacacaaagc ctgtttggtg 5820 gtctcttcac acggacgcgc gtgaaa 5846 <210> 3 <211> 4729 <212> DNA <213> Homo sapiens <400> 3 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac gtatacatcc 60 agatggtctg aagtaactga agatccacaa aagaagtaaa catagcctta actgatgaca 120 ttccaccatt gtgatttgtt cccgccccac cctaactaat caatgtactt tgtaatctcc 180 cccaccctta agaaggttct ttgtaattct ccccaccctt gagaatgtac tttgtgagat 240 ccacccctgc ccacaaaaca ttgctcttaa cttcaccgcc tatctcaaaa cctataagaa 300 ctaataataa tccaccactc tttgctgact ctctgtttgg actcagccca cctgcaccca 360 ggtgaaataa acagccatgt tgctcacaca aagcctgttt ggtggtctct tcacacggac 420 gcgcatgaaa tttggtgtcg tgactcagat tgggggacct cccttgggag atcaatcccc 480 tgtcctcctg ctctttgctc tgtgagaaag atccacctac gacctcagga ccgaccagcc 540 caagaaacat ctcaccaatt tcaaatccag taagcggcct ctttttactc tcttctccaa 600 cttgcctcac tatccctcaa cctctttctc ctttcaatct tggcgctaca cttcaatctc 660 tcccttctct taatttcaat tcctttcatt ttctggtaga gacaaaagag acacgtttta 720 tccgtggacc caaaactccg gcgccggtca cggactggga aggcagcctt cccttggtgt 780 ttaatcattg cagggatgcc tctgtgatta tacacccacg tttcaagggt gtcagaccac 840 gcagggacgc ctgccttggt ccttcaccct tagcggcaag tcctgctttt ctggggaagg 900 ggcaagtacc ccaacccctt ctctccttgt ctctacccct tctctgcctt tcctggggca 960 ggggcaagta cccctcaacc ccttctcctt cacccttagc ggcaagtccc gctttcctag 1020 gggcaagaac ctcccaatcg cttatttccg caccccaacc tcttatctct gtgccccaat 1080 cccttatttc cgtgccccaa ccctttctct gcttttctgg agggcaagaa ctccccaccc 1140 cttctccatg tctctactct tttctctggg cttgcctcct tcactatggg taggcttcca 1200 ccttccattc ctccttgttc tcccttagcc tgtgttctca aaaacttaaa acctcttcaa 1260 ctcacacctg acctaaaacc taaatgcctt attttcttct gcaatgccgc ttgaccccaa 1320 tacaaactcg acagtagttc caaatagctg gaaaacggcg ctttcaattt ttccatccta 1380 caagatctaa ataattcttg tcgtaaaatg ggcaaatggt ctgaggtgcc tgacgtccag 1440 gcattctttt acacatcagt cccttcctag tctctgtgcc ccgtgcaact cgtcccaaat 1500 cttccttctt tccctccctc ctgtcccctc agtcccaacc ccaagcggcg ctgagtcttt 1560 ctaatcttcc tcttctacag acccatctga cctctcccct ccgcgccagc ccaagctagg 1620 tcccaattct tcctcagcct ccgcgcctcc cctcccttca tcccacacct ggtccgactt 1680 atagtttcat tctgtgacta gccctccccc acctgcccag cagtttactc ttaaaaaggt 1740 ggctggagcc aaaggcatag tcagggttaa tgctcctttt tcattatccc aaatcacata 1800 gcgtttaggc tctttttcat caaatataaa aacccagccc agttcatggc tcgttcggca 1860 gcaaccctga gacgctttac agccctagac cctaaaaggt caaaaggcca tcttattctc 1920 aatatacatt ttattacccg atctgctccc gacattaaat aaaactccaa aaattaaatt 1980 ccggccctca aaccccacaa caggatttaa ttaacctcgc cttcaaggtg tacaataata 2040 gaaaaaagtt gcaattcctt ggctccactg tgagacaaac cccagccaca tctccagcat 2100 acaagaactt ccaaatgcct gaaccgcagc ggccaggcgt tcttctagaa cctcctcccc 2160 caggagcttg ctacaagtgc cagaaatctg accaccaggg caaggaatgc ctgcagccca 2220 ggattcctcc taagccgtgt cccatctgtg cgggacccca ctggaaatta gactgttcaa 2280 ctcacctggc agccactccc cgagcccctg gaactctggc ccgaggctct ctgactgact 2340 ccttctcggc ttagcggctg aagactgatg ctgcccgatc gcctcggaag ccccgtaggc 2400 catcacggac gccgagcttt gggtaactct cagagtggaa ggtaagtccg tccccttctt 2460 aatcaatatg gaggctaccc actccacatt accttctttt caagggcctg tttcccttgc 2520 ctccataact gttgtgggta ttgacagcca ggcttctaaa cctcttaaaa ctccccaact 2580 ctggtgccaa cttagacaac actcttttaa gcactctttt ttagttatct ccacctgccc 2640 acttccctta ttaggccgag atattttaac caaattatct gcttccctga ctattcctgg 2700 actacagccg catctcattg ctgcccttct tcccaatcca aagcctcctt tgcgtcctcc 2760 tcttgtattc ccccacctta acccacaagt ataagagacc tctactccct ccttggtgac 2820 tgatcacgca ccccttacca tctcattaaa actgaatcac ccttaccccg ctcaacgcca 2880 atatcctatc ccacagcatg ctttaaaagg attaaagcct gttatcactc gcctgctaca 2940 gcatgggcac ctataaactc tccttaccat tcccccattt cacctgtcct aaaaccaggc 3000 aaggcttaca agttagttca gaatctgcac cttatcaacc aaattgtttt gcctatccac 3060 cctgtggtgc caaacccata tactctccta tcctcaatac ctccctctac tacccattat 3120 tctgttctgg atctcaaaca tgctttcttt actattcctt tgcacccttc atcccagcct 3180 ctctttgcct tcacttagac tgaccctgac acccattagg ctcagtaaat tacctgggct 3240 gtactgccgc aaggcttcgc ggacagcccc cattacttca gtcaagccca aatttcatcc 3300 tcatctgtta cctatctcgg cataattctc atagaaacac atgtgctctt cctgctgatc 3360 atgtccgatt aatctcccaa acctcaatcc cttacaaaag aacaactcct ttccttccta 3420 ggcatggtta gtgcggtcag aattcttaca caagagccag gaccacaccg tgtagccttt 3480 ctgtccaaac aacttgacct tactgtttta gcctagccct catgtctgcg tgcagcggct 3540 gccgctgctt taataccgtt agaggcccta aaaatcacaa actatgctca actcactctc 3600 tacatttctc ataacttcca aaatctattt tcttcctcat acctgacaca tatactttct 3660 gctccccggc tccttcagct gtactcactc tttaagtccc acaattacca ttgttcctgg 3720 cccggacttc aatctggcct cccacattat tcctgatacc acacctgacc cccatgactg 3780 tatctctctg atccacctga tattcacccc atttccccat atttccttct ttgctgttcc 3840 tcaccctgat cacgcttgcc tcgtgctatc cccaaactgc cattcttaac tcttgaagta 3900 aataatcttt gctggcaggg ctatgctgaa tctccttagg cactctctaa tcagatgtcc 3960 tgagtcgtcc caattcttag accttttata cctgtttttc tccttctctt attccattta 4020 gtttttcaat tcatacaaaa ccatatccag gccatcacca ataattctac acaacaaatg 4080 tttcttctaa caaccccaca atatcacccc ttaccacaaa atcttccttc agcttaatct 4140 ctcccactct aggttcccac gccaccccta atcccgctcg aagcagccct gagaaacatc 4200 gcccattctc tctccacacc aacccccaca aattttcacc gccccaagac ttcaacacta 4260 ttttgtttta tttttcttat taatataaga aggcaggaat gtcaggcctc tgagcccaag 4320 ccaagccatc gcatcccctg tgacttgcac gtatacatcc acgtggcctg aagtaactga 4380 agatccacaa aagaagtaaa catagcctta actgatgaca ttccaccatt gtgatttgtt 4440 cccgccccac cctaactaat caatgtactt tgtaatctcc cccaccctta agaaggttct 4500 ttgtaattct ccccaccctt gagaatgtac tttgtgagat ccaccccgcc cacaaaacat 4560 tgctcttaac ttcactgcct aacccaaaac ctataagaac taataataat ccaccactct 4620 ttgctgactc tctttttgga ctcagcccac ctgcacccag gtgaaataaa cagccatgtt 4680 gctcacacaa agcctgtttg gtggtctctt cacacagacg cgcatgaaa 4729 <210> 4 <211> 4609 <212> DNA <213> Homo sapiens <400> 4 gtcaggcctc tgagcccaag ccaacccatc gcatcccctg tgacttgcac gtatacgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aaggccctgc cccgccttaa 120 ctgatgacat tccaccattg tgatttgttc ctgccccacc ttaactgagt gattaaccct 180 gcaaatttcc ttctcctggc tcagaagctc ccccactgag caccctgtga cccccacccc 240 tgcccaccag agaacaaccc cctttgactg taattttcca ttaccttccc aaatcctata 300 aaacggcccc acccctatct ccctttgctg actctctttt tggactcagc ccgcctgcac 360 ccaggtgaaa taaacagcca tgttgctcac acaaagcctg tttggtggtc tcttcacaca 420 gatgcgcaag aaatttggtg ccgtgactcg gatcagggga cctcccctgg gagatcaatc 480 ccccgtcctc ctgctcttta ctccatgaga aagacccacc tacgacctca ggtcctcaga 540 ccaaccagcc caagaaacat ctcaccaatt tcaaatccgg taagcggcct ctttttactc 600 tcttctccaa cctccctcac tatccctcaa cctctttctc ctttcaatct tggcgccaca 660 cttcaatctc tcccttctct taatttcaat tcctttcatt ttctggtaga gacaaaggag 720 acatgtttta tccgtgtacc caaaactccg gcgccagtca cggactggga aggcagcctt 780 cccttggtgt ttaatcattg cagggacgcc tctctgatta tacacccacg tttcaagggt 840 gtcagaccac gcagggacac ctgctttggt ccttcaccct tagcggcaag tcccgctttt 900 ctggggaagg agcaagtacc ccaacccctt ctctccttgt ctctacccct tctctgcttt 960 tccagggaca gggcaagtac cccaacccct tctctccttg tctctacccc ttctctgctt 1020 ttccggggag agggcaagta ccccaacccc ttctctcctt gtctctaccc cttctctgct 1080 tttccaggga cagggcaagt accccaaccc cttctctcct tgtctctacc ccttctctgc 1140 ttttctggga gaggggaaag tacccctcaa ccccttctcc ttcaccctta gcggcaagtc 1200 ccgctctcct agggggcaag aaccccccaa tcgcttattt ccatgcccca acctctgatc 1260 tctgcgcccc aatcacttat ttccatgccc caacctctta tgtctgtgcc ccaatccctt 1320 ttttccacac cccaacctct tatttctgta ccccaatccc ttatttccat gccccaaccc 1380 tttctctgct tttctggagg gcaagaaccc cccacccctt ctccgtgtct ctactctttt 1440 ctctgggctt gcctccttta ctatgggcaa gcttccacct tccattcctc cttcttctcc 1500 cttagcctgt attcttaaga acttaaaacc tcttcaattc tcacctgacc taaaatctaa 1560 gcgtctcatt ttcttctgca atgccgcttg accccaatac aaactcgaca gtagttccaa 1620 atagccagaa aacggcactt tcaatttttc catcctacaa gatctaaata attcttgtcg 1680 taaaatgggc aaatggtctg aggtgcctga cgtccaggca ttcttttaca catcagtccc 1740 ttcctagtct ctgtggccag tgcaactcgt cccaaatctt ccttctttcc ctcccgcctg 1800 tcccctcagt accaacccca agcgtcgctg agtctttcta atcttccttt tctacagacc 1860 catctgacct ctcccttcct ccccaggctg ctcctcgcca ggccgagcta ggtcccaatt 1920 cttcctcagc ctccgctcct ccaccctata atccttttat cacctcccct cctcacacct 1980 gctccggctt acagtttcgt tccgtgacta gccctccccc tcctgcccag caatttactc 2040 ttaaaaaggt ggctggagcc aaaggcatag tcagggttaa tgctcctttt tctttatccc 2100 aaatcagata gtgtttaggc tttttcatca aatataaaaa cccagcccag ttcatggctc 2160 attcggcagc aaccctgaga cgctttacag ctctagaccc taaaaggtca aaaggccgtc 2220 ttatgctcaa tatacatttt attacccaat ctgccccgga cattaaataa aactccaaaa 2280 attaaatccg gccctcaaac cccacaacag gacttaattg acctcacctt caaggtgtag 2340 aataataaaa aaaaaaagtt gcaattcctt gcctccgctg tgagacaaac cccagccaca 2400 tctccagcac acaagaactt ccaaatgcct gaaccacagc agccaggcgt tcctccagaa 2460 cctcctccca caggagcttg ctacatgtgc cggaaatctg gccactaggc caaggaatgc 2520 ctgcagcccc ggattcctcc taagccgtgt cccatctgtg cgggacccca ctgaaaatcg 2580 gactgttcaa ctcacctggc agccactctc agagaccctg gaactctggc ccaaggctct 2640 ctgactcctt cccagatctt cttggcttag cggctgaaga ctgacactgc ccgatcgcct 2700 cggaagcccc ctagaccatc atggacgccg agcttcgggt aactctcaca gtggaaggta 2760 agcccgtccc cttcttaatc aatacggagg ctacccactc cacattacct tcttttcaag 2820 ggcctgtttc ccttgcctcc ataactgttg tgggtattaa cagccaggct tctaaacctc 2880 ttaaaactcc ccaactctgg tgccaactta gacaatactc ttttaagcac tcctttttcg 2940 ttatccccac ctgcccagtt cccttattag gctgagacac tttaactaag ttatctgctt 3000 ccctgactat tcctggacta cagccacatc tcattgccgc ccttctcccc aacccaaagc 3060 ctccttcgcg tcttcctctc atatcccccc accttaaccc gcaagtatgg gacatctcta 3120 ctccttccct ggcaaccgat cacatgcccc ttaccatccc attaaaacct aatcaccctt 3180 accccgctca acgccaatat cccatcccac agcacgcttt aaaaagatta aaacctgtta 3240 tcactcgcct gctacagcgt ggccttttaa agcttataaa ctctccttac cattccccca 3300 ttttacctgt cctaaaacca gacaagcctt acaagttagt tcagaatctg cgccttatca 3360 accaaattgt tttgcctatc caccccgtgg tgccaaaccc atagactctc ctatcctcaa 3420 tacctccctc tactacccat tattctgttc tggatctcaa acatgctttc tttactattc 3480 cttgcaccct tcatcccagc ctctctttgc cttcacttag actgaccctg acacccatta 3540 ggctcagcaa attacctggg ctgtactgct gcaaggcttc acagacagcc cccattactt 3600 cagtcaagcc caaatttcat cctcatctgt tagtcatact cctattcact gttctcaact 3660 actcacacat gccctgctct tgtttacact gccggtttac actctttctc caagacatca 3720 caggtgatat ctcctagtgc tatccccaaa ctgccactct aaactcttga agtaaataaa 3780 taatctttgc cggcaggact atgctgaatc tccttaggca ctctctaatt agatggccta 3840 ggtcctccca attcttagtc cttttatacc tgtttttcgc cttctcatat tccatttagt 3900 ttttcaattc atacaaaacc gtatccaggc catcaccaat cattctatat gacaaatgtt 3960 tcttcttaca tccccacaat atcacccctt accacaagac ctcccttcag cttaatctct 4020 cccactctag gttcccacgc cgcccctaat cccacttgaa gcagctctga gaaacatcac 4080 ccattctctc tccataacac ccccaaaaat ttttgccgcc tcaacacttc aacactattt 4140 tgttttattt ttcttattaa tataagaagg caggaatgtc aggcctctga gcccaagcca 4200 agccatcgca tcccctgtga cttgcacgta tacgcccaga tggcctgaag taactgaaga 4260 atcacaaaag aagtgaaaag gccctgcccc gccttaactg atgacattcc actattgtga 4320 tttgttcctg ccccacctta actgagtgat taaccctgcg aatttccttc tcctggctca 4380 gaagctcccc cactgagcac cttgtgaccc cccacccctg cccaccagag aacaaccccc 4440 tttgactaat tttccattac cttcccaaat cctataaaac ggccccaccc ctatctccct 4500 tcgctgactc tcttttcgga ctcagcccac ctgcacccag gtgaaataaa cagccatgtt 4560 gctcacacgg agcctgtttg gtggtctctt cacacagacg cgcatgaaa 4609 <210> 5 <211> 6026 <212> DNA <213> Homo sapiens <400> 5 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac gtatacgccc 60 agatggcctg aagtaactga agaatcacaa aagaactgaa aaggccctgc cccgccttaa 120 ctgatgacat tccaccatgg tgatttgttc ttgccccacc ttaactgagt gattaaccct 180 gtgaatttcc ttctcctggc tcagcagctc ccccactgag caccttgtga cccccgcccc 240 tgcccaccag agaacaaccc cctttgactg taattttcca ttaccttccc aaatcctata 300 aaacggcccc accccatctc ccttcgctga ctctcttttc ggactcagcc cgcctgcccc 360 caggtgaaat aaacagccat gttgctcaca caaagcctgt ttggtgtctc ttcacatgga 420 ctcgagtgaa ctttgatgcc gtggctcgga tcgggggacc tcccttagga gatcaatccc 480 ccgtcctcct gctctttgct ccatgagaaa gatccaccta cgaccttagg tcctcagacc 540 aaccagccca agaaacatct caccaatttt aaatccagta agccgcctct ttttactctc 600 ttctccaacc tccctcacta tccctcaacc tctttctcct ttcaatcttg gcgccacact 660 tcaatctctc ccttctctta gtttcaattc ctttcatttt ctggtagaga caaaggagac 720 acgttttatc tgtggaccca aaactccagc gctggtcacg gactgggaag gcagccttcc 780 cttgctgttt aatcattgca gggacacctc tctgattatt cacccacgtt tcaagggtgt 840 cagaccatgc agggatgcct gccttggtcc ttcaccctta gcggcaagtc ccgcttttct 900 ggggaagggg aaagtacccc aaccccttct ctctgtgtct ctacccgttc tctgcttttc 960 tggggaaggg gcaagtaccc caaccccttc tctctgtgtc tctacccctt ccctgctttt 1020 ctggggaagg ggcaagtacc ccaacccctt ctcttcttgt ctctacccct tctctgattt 1080 tctggggcag gggcaagaac ccctcaaccc cttctccttc acccttagtg gcaagtccca 1140 cttttctggg ggaggggaaa gtacccctca accccttctc cttcaccctt agtggcaagt 1200 cccgcttttc tagggggcaa gaacccccaa tcccttattt ccacaccccg acctcttatt 1260 tctgtgaccc aatcccttat ttccacaccc caacctctta tctctgtgcc ccaatccctt 1320 atttccatgc cccaaccccc cttcccactt ttctaggggg caagaacccc caatccctta 1380 tttccacacc ctgacctctt atctctgtgc cccaatccct tatttctgtg ccccaaccct 1440 ttctctgctt ttctggaggg caagaaaccc ccaccccttc tccgtgtctc tactcttttc 1500 tctgggcttg cctccttcac tatgggcaag cttccacctt ccattcctcc ttcttctccc 1560 ttagcctgta ttcttaagaa cttaaaacct cttcaactct cacctgacct aaaatctaag 1620 tgtctcattt tcttctgcaa tgcctcttga ccccaataca aactctacag tagttccaaa 1680 tagccggaaa acggcacttt caatttttcc atcctacaag atctaaataa ttcttgtcat 1740 aaaatgggca aatggtctga ggtgcctgac atccaggcat tcttttacac atcagtccct 1800 tcctagtctc tgtgcccagt gcaactcatt ctgaatcttc cttctttccc tcccgcctgt 1860 cccctcagtc ccaaccccaa gcgtcactga gtctttctaa tcttcctttt ctacagaccc 1920 atctgacctc tcccctcctt gccaggccaa gctaggtccc aattcttcct cagcctccgc 1980 tcctccaccc tgtaatcttt ttatcgcctc ccctcctcac acctggtctg gcttacagtt 2040 tcgttctgtg actagccctc ccccacctgc ccagcaattt actcttaaaa aggtggctgg 2100 agccaaaggc atagtcaagg ttaatgctcc tttttcttta tcccaaatca gaagcgttta 2160 ggctcttttt catcaaatat aaaaacccag cccagttcat gtctcgttcg gcagcaaccc 2220 tgagatgctt tacagcccta gaccctaaaa ggtcaaaagg ccatcttatt ctcaatacac 2280 attttattac ccaatctgct cccgacatta aataaaactc caaaaattag aatctggccc 2340 tcaaacccca caacaggact taattaacct caccttcaag gtgtacaata ataaaaaaaa 2400 ggaagttgca attccttgcc tccactgtga gacaaacccc agccacatct ccagcacaca 2460 acaacttcca aatgcctgaa ccgcagtggc cagacattcc tccagaacct cctcccccag 2520 gagcttgctg caagtgccag aaatctgacc accagggcaa ggaatgcctg cagcccaggg 2580 attcctccta agccatgtcc catctgtgcg ggaccccact ggaaatcgga ctgttcaact 2640 cacctggcag ccactcccag cgcccctgga actctggccc aaggctctct gactgactcc 2700 ttcttggctt agtggctgaa gactgacgct gcctgatcgc ctcagaagcc ctgtagacca 2760 ccatggacac cgagctttag gtaactctca cagtggaggg taagtctgtc cccttcttaa 2820 tcaatatgga ggctacccac tccacattac cttcttttca agggcctgtt tcccttgcct 2880 ccataactgt tgtgggtatt gacagccagg cttctaaacc tcttaaaact ccccaactct 2940 ggtgccaact tgaacaacac tcttttatgc actctttttt agttatctcc acctgcccag 3000 ttcccttatc aggccgagat attttaacca aattatctgc ttccctgact attcctggac 3060 tacagctgca tctcattgct gcccttcttc ccaatccaaa gcctcctttg cgtcctcctc 3120 ttgtattccc ccaccttaac ccacaagtat aagatacctc tactccctcc ttggcgaccg 3180 atcatgcacc ccttaccatc tcattaaaac ctaatcacgc ttacccgact caatgccaat 3240 atcccatccc acagcatgct ttgaaaggat taaagcctgt tatcactcac ctgctacagc 3300 atggcctttt aaagcctata aactctcctt acaattcccc cgttttacct gtcctaaaac 3360 cagacaaggc ttacaactta gttcagaatc tgtgccttat caaccaaatt gttttgccta 3420 tccaccccgt ggtgccaaac ccatatactc tcctatcctc aatacctccc tctactaccc 3480 attattctgt tctggatctc aaacatgctt tctttactat tcctttgcac tcttcatctc 3540 agcctctctt tgccttcact tagactgacc ctgacaccca ttaggctcag cagcttacct 3600 gggctgtgct gccgcaaggt tccagggaca gccctcatta cttcagccaa gctctttctc 3660 atgatctact ttctttccac ccctccactt ctcaccttat tcaatatatt gatgaccttc 3720 ttctttgtag cccctccttt gaatcttctc aacaagacat acttctgctc cttcagcatt 3780 tattctccaa aggatatcgg gtatccccct ccaaagctca aatttcttct ccatccgtta 3840 cctacctcgg cataattctt cacaaaaaca caggtgctct ccctgctgat ggtgtctgat 3900 taatctccca aacctcaatc ccttacaaaa caacaactcc tttccttcct aggcatggtt 3960 agtgcggtca gaattcttac acaagagcca ggaccccacc ctgtagcctt tctgtccaaa 4020 caacttgacc ttactgtttt agcctagccc tcatgtctgc atgcagcagc tgccgctgct 4080 ttaataattt tagaggccct aaaaatcaca aactatgttc aactcactct ctacatttct 4140 cataacttcc aaaatctatt ttcttcctca tacctgacgc atatactttc tgctccccgg 4200 ctccttcagc tgtactcatt ctttgttaag tcccacaatt accattgttc ctggcccaga 4260 cttcaatctg gcctcccaca ttattcctga taccacacct gatccccatg actgcatctc 4320 tctgatccac ctgacattca ccccatttcc ccatattaca agccactagc ccatctctta 4380 gaacctctca tttcctttcc attgtagaaa tctatcctca aggaaataac ttctcagtgt 4440 tccatctgct attctatctg ctattctgct actcctcaag gatcattcag gcccctccct 4500 tccctacaca tcaagctcga ggatttgccc ccgcccagga ctggcaaatt agctttactc 4560 cacatgcccc gagtcacaaa aactaaaata cctcttagtc taagtagaca ttttcactag 4620 ataggtagag gcctttccta cagggtctga gaaggccacc gcagtcattt cttcccttct 4680 gtcagacata attcctcagt ttagccttcc cacctctata cagtctgata acagaccagg 4740 ctttattagt caaattagcc aagcagtttt tcagtttata tcccttatag tcctctgtct 4800 tcaagaaaag tagaacggac taaaggtctt ttaaaaacac acctcaccaa gctcagccac 4860 caacttaaaa agaactggac aatactttta ccactttccc ttctcagaag tcagacctgt 4920 cctcagaatg ctacaaggta cagtccattt aagctccttt ttattaggcc ccagtctcat 4980 cccagacacc agaccaactt agactgtgcc cccaaaaaaa cttgtcatcc ctactatttt 5040 ccgtctagtc atactcctat tctccgttct caactactca tacatgccct gctcttgttt 5100 acactgccag tttacactgt ttctccaagc catcatggct gatatctcct catgctatcc 5160 ccaaactgcc actcttaact cttgaagtaa ataaataatc ttcgctggaa ggactatgct 5220 gaacctcctt aggcattctc taattagatg tcctagatcc tcccaattct tagtcctttt 5280 atacctgttt ttctccttct cttattccat ttagtttttc agttcataca aaaccgtatc 5340 caggccatca ccaatctttc tgtatgacaa atgtttcttc taacaacccc ctcaatgtca 5400 ccccttacca caagacctcc cttcagctta atctctccca ctctaggttc ccacgccgcc 5460 cctaatcccg cttgaagcag ccctgagaaa catcgcccat tctctctcca taccaccccc 5520 caaaaatttt caccgcccca acacttcaac acaattttgt tttatttttc ttattaatat 5580 aagaaggcag gaatgtcagg cctctgagcc caagccaagc catcgcatcc cctgtgactt 5640 gcacgtatac gcccagatgg cctgaagtaa ctgaagaatc acaaaagaac tgaaaaggcc 5700 ctgccccgcc ttaactgatg acattccacc atggtgattt gttcttgccc caccttaact 5760 gagtgattaa ccctgtgaat ttccttctcc tggctcagaa gctcccccac tgagcacctt 5820 gtgacccccg cccctgccca ccagagaaca accccctttg actgtaattt tccattacct 5880 tcccaaatcc tataaaacgg ccccacccct atctcccttc gctgactctc ttttcggact 5940 cagcccgcct gcccccaggt gaaataaaca gccatgttgc tcacacaaag cctgtttggt 6000 gtctcttcac acggacgcgc atgaaa 6026 <210> 6 <211> 2771 <212> DNA <213> Homo sapiens <400> 6 tgggtcaggt acaaataagc ccaccccact aggaactatg ttaaaaaaaa attcaagaaa 60 gaatttaagg gagattacag tgttactgtg acaccaggaa aacttagaac tttgtgtgaa 120 atagactggc cagcattaga ggtgggttgg ccatcagaag gaagcctgga caggtccctt 180 gtttcaaagg tatgacacaa ggtaacccgt aagccaaggc acccagacca gtttccatac 240 atagaaagtt acagctgctt ttataccccc ttgccccgcc aacgtagtta agagaacagc 300 agcataagcg gctggcagag gcaaggaaag accagtagag agaaaaaaag gccatctata 360 ccaattctaa gttaatttag actaaacaag gtcttaatag caaaggataa ttgaaatccc 420 aaacttacaa ggttttcaac aaaagtgaag tttgcttaaa gttaacagtg taacatgtat 480 tatggtaact tctaatcttg tggccttaga cagtctagtc caaaggcata aagaaagttt 540 gctttaaaaa aaaaaaaaag gaatggttat cttcaaaaaa aaaaaaagtg gggggagaca 600 gaatttatgt aaaaagagtg ttatatggta aattcttgtc ctgaaataaa ctaactggtg 660 tttaaagaaa aaaaatgttt gtaataagtc agaaagttga gacacattga agaattgtcg 720 gcaaaagtcg tgaaagaaaa aatgttataa aaaaatttat gcaaaaaatg ttgtataatt 780 taaaagtaat aaggcctcct gagtactatt aaaaaaacag tttatgtgca aggtgtataa 840 gaaaagtaaa acataccttt ggtaaaaaga ttataaaggg gcataagaat gtggattttt 900 acctacatta aaaggttaaa aacaattatt gttttaaaag tttaagcaag ttttaaaacg 960 ttaattataa agaaaattct gtgtgtaaac atattagcta aagttaaaaa ggtatcatcc 1020 agtttttctg tgaactggac attaaagtaa aaaatgccac aggtttttct taaagcatca 1080 acctgctctt taacaaaaat tataaaaggt taaaaagagt ctataaaatc ttaccttatg 1140 gtcaaacatg aaaaattgga taaatatgtc tacaaggttt tattaaaatt cagtttaaaa 1200 ttaataacac actaatataa aggtaaaatt tagcttatct ggtataaaaa tcatacaaga 1260 aacattatta aatataaaat ggtgtttagc tttctttggt ctaaaaacta ataaaaattg 1320 gtgctaaagg aaacattcat tttactagag gatcataaaa gttaaagact taaaacaaac 1380 tttggcaatt aagacagcac gccaagatgc aagtgcctgg ctgaaatgga tcaaatattc 1440 catctgcact ttaaacaaat gcaattgtta tgcttgtgca catggcaggc cagaggccct 1500 gattgtcccc cttccactaa ggtggtcctc cagttgacca ggcatgggct gcagggtagc 1560 tattttccag gtttctacag cttggagtaa taagtcatgc caagctctct ctgctatatc 1620 ccaaagtccc tgcgggtcag cccctgaggg ccgtccagct tccgtctccc aacactaagt 1680 tcacttcatg tctctcatgg cagggaggag acttagcatt ccttggagac ctgaagggat 1740 gcagtgagct taagaatttt caagagctta tcagtcagtc agcccttgtt catccccgag 1800 cggatgtgtg atggtattgt cgtggacctt tattgggcac tctgccgaat aactagagtg 1860 gcacttgtgc tttagcctat ttggctatcc ctttcaccct ggcatttcat caaccagagg 1920 aaggaaaaaa aaaataataa gacatcgtaa agcgagagaa gccccttatg ggtctttcaa 1980 ctctcacatc tatttagatg caatcgaagc cccgcaagga acaccagatc aatttaaagt 2040 ccgaaatcaa atagctacag gatttaagtc aatattttgg tagatgacag tcaataaaaa 2100 tgtagattag ataaactgca tctattacac ccaacagcaa tgagcttttc atgagttgaa 2160 aaaaagaaaa aacccatgtc ggccccagcc ctggggctac ctgacctgac aaaacctttt 2220 acactctatg tgtcagaaag agaaaaagtg gcagttggag ttttaaccca gactgtaggg 2280 ccctggccaa ggccagtggc ctatctctca aaacaactag atgaggtttc caaacgctgg 2340 cccccatgtc caaagtccct ggtagcaata gccctgttag cacaagaagc agataagcta 2400 actcttagac aaaacctaaa cataaagtcc ccctatgctg tggtgatttt aataaatacc 2460 aaaggacacc attagctaat gaatgctaga ctagctagat accaaagctt gctctgtgaa 2520 catccccgca taaccattga agtttgcaac acctaaaccc cgccaccttc ctcccggtgt 2580 cagagagccc agttaaacat aactgtgtag aggtattgga ctcagtttat tctagtgggc 2640 ctaaccaccg agaccatcct taaacatcag tagactggga gctgtacatg gatgggagca 2700 gcttcaccaa cccctgcaaa gtgactctga agaagacgac aagccctgct ccagtcacac 2760 ccggaagctg a 2771 <210> 7 <211> 5535 <212> DNA <213> Homo sapiens <400> 7 aactgaagat ccacaaaaga agtaaaaaca gccttaactg atgacattcc accattgtga 60 tttgttcctg ccccacccta actgatcaat gtactttgta atctccccca cccttaagaa 120 ggttctttgt aattctcccc acccttgaga atatactttg tgagatccac ccctgcccac 180 cagaggacaa ccccctttga ctgtaatttt ccattacctt cccaaatcct ataaaacggc 240 cccacccgta tctcccttcg ctgactctct tattggactc agcccacctg cacccaggtg 300 aaataaacag ccatgttgct cacacaaagc ctgtttggtg gtctcttcac acagacgcgc 360 atgaaatttg gtgccgtgac tcggatcggg ggacctccct tgggagatca atcccctgtc 420 ctgctgctct ttgctccgtg agaaagatcc acctatgacc tcaggtcctc agaccgacca 480 gcccaagaaa catcgcacca atttcaaatc cggtaagcgg cctcttttta ctctcttctc 540 caacttccct cactatccct caacctcttt ctcctttcaa tcttggcgct acgcttcaat 600 ctctcccttc tcttaatttc aattcctttc attttctggt agacacaaaa gagacgtttt 660 atccgtggac ccaaaactcc ggcgccggtc acggactggg aaggcagcct tcccttggtg 720 tttaatcaat gcagggacgc ctctctgatt atacacccac gtttcaaggg tgtcagacca 780 cgcagggaca cctgccttgg tccttcaccc ttagcggcaa gtcctgcttt tctggggaag 840 gggcaagtag cccaacccct tctctccttg tctctacccc ttctctgctt tcctggggca 900 ggggcaagta cccctcaacc ccttctcctt cacccttagc ggcaagtccc gctttcctgg 960 ggcaggggca agtacccctc aaccccttct ccttcaccct tagcggcaag tcctgctttt 1020 ctagggggca agaaccccca aaccacttcc ctccgtgtct ctacgctctc tgttctctgg 1080 gcttgcctcc ttcactatgg gcaagcttcc accttccatt cctccttctt ctcccttagc 1140 ctgtgttctt aagaacttaa aacctcttca actctcacct gacctaaaat ctaagcatct 1200 tattttcttc tgcaatgccg cttgacccca atacaaactc gacagtagtt ccaaatagcc 1260 agaaaacagc actttcaatt tttctgtcct acaagatcta aataattcct gtcgtaaaat 1320 gggcaaattg tctgaggtgc ctgacgtcca ggcattcttt tacacatcag tccattccta 1380 gtctctgtgc ccaatgcaac tcgtcccaaa tctcccgcct gtcccctcag tcccaacgcc 1440 aagcatcgct gagtctttct aatcttcctt ttctacagac ccatctgacc tctcccctcc 1500 tagccaggcc aagctaggtc ccaattcttc ctcagcctcc actcctccac cctataatct 1560 ttttatcgct tcccctcctc acacctggtc gggcttacag tttcattccg tgactagccc 1620 tcccccacct gcccagcaat ttattcttaa aaaggtggct ggagctaaag gcatagtcaa 1680 ggttaatgct cctttttatt tatcccaaat cagatagcgt ttaggctttt tcatcaaata 1740 taaaaaccct gcccagttca tggctcgttc ggcagcaacc ctgagactct ttacagccct 1800 agaccctgaa aggtcaaaag gccatcttat tctcaatata cattgtatta cccaatctgc 1860 tcccgacatt aaataaaact ccaaaaatta aattctggcc ctcaaacccc acaacaggat 1920 ttaattaacc tcgccttcaa ggtgtacaat aatagaaaaa agttgcaatt ccttgcctcc 1980 actgtgagac aaaccccagc cacatctcca gcacacaaga acttccaaac gcctgaacca 2040 cagcagccag gcttcctcca gaacctcctc ccccaggagc ttgctacaag tgccagaaat 2100 ctgaccacca ggccaaggaa tgcctgcagc ccaggattcc tcctaagcca tgtcccatct 2160 gtgcgggacc ccactggaaa ctggactgtt caactcacct ggcagccact cccagagccc 2220 ctggaactct ggcccaaggc tctctgactg actccttctc ggcttagcgg ctgaagactg 2280 atgctgcccg atcgcctcgg aagccccgta gaccatcacg gacaccgagc tttgggtaac 2340 tctcacagtg gaaggtaagt ccgtcccctt cttaatcaat atggaggcta cccactccac 2400 attaccttct tttcaagggc ccgtttccgt tgcctccata actgttgtgg gtattgacgg 2460 ccaggcttct aaacctctta aaactcccca actctggtgc caacttagac aatactcttt 2520 taagcactcc tttttagtta tccccacctg cccagttccc ttattaggct gagacacttt 2580 aactaaatta tctgcttccc tgactattcc tggactacag ctacatctca ttgccgccct 2640 tcttcccaat ccaaagcctc ctttgtgtcc tcctcttata tccccctacc ttaacccaca 2700 agtataagat acctctactc cctccttggc gaccgatcat gcacccctta ccatctcatt 2760 aaaacctaat cacccttacc ccgctcaatg tcaagatccc atcccacagc acgctttaaa 2820 aggattaaag cctgttatca ctcgcctgct acagcatgac cttttaaagc ctataaactc 2880 tccttaccat tcccctgttt tacctgtcct aaaaccagac aaggcttaca agttagttca 2940 gaatctgcgc cttatcaacc aaattgtttt gcctatccaa ctcgtggtgc caaatccata 3000 tactctccta tcctcaatac ctctctctac tacccattat tctgttctag atctcaaaca 3060 tgctttcttt actattcctt tgcacgcttc atcccagcct ctctttgctt tcacttagac 3120 tgaccctgac acccatcaag ctcagcaaat taccttggct gtactgccgc aaggcttcac 3180 agacagcccc cattacttca gtcaagccca aatttcaccc tcatctgtta cctatctcgg 3240 ccaaattctc ataaaaacac acgtgctttc cctgctgatc gtgtctgatt aatctcccaa 3300 acctcaatcc ctttcaaaac aacaactcct ttccttccta ggcatggtta gtgcggtcag 3360 aattcttaca caagagccag gaccgcaccc tgtagccttt ctgtccaaac aacttgacct 3420 tactgtttta gcctagccct catgtctgcg tgcagcggct gccgctgctt taatactttt 3480 agaggccctc aaaatcacaa actatgctca actcactctc tacatttctc ataacttcca 3540 aaatctattt tcttcctcat acctgatgca tatactttct gcttcccggc tccttcagct 3600 gtactcactc tttaagtccc acaattacca ttgtttctgg cccggacttc aatccggcct 3660 cccacattat tcctgatacc acacctgaca cccatgactg tatctctctg atccacctga 3720 tattcacccc atttccccat atttccctct ttcctgttcc tcaccctgat cacgcttgat 3780 ttattgatgg cagttccacc aggcctaatc gccgcatacc agcaaaggca ggttatgcta 3840 tagtacaagc cactagccca cctctcagaa cctctcattt cctttccatc gtggaaacct 3900 gtcctcaagg aaataacttc tcagtgttcc atctgctatt ctactactcc tcagggatta 3960 ttcaggcccc ctcccttccc tacacatcaa gttcgaggat ttgcccctac ccaggactgg 4020 caaattagct ttactcaacg tgcctgagtc aggaaactaa aatacctctt agtccaaata 4080 gacactttca ctgaataagt aaaggtcttt cctacagggt ctgagaaggc caccgcagtc 4140 atttctttcc ttctgtcaga cataattcct cagtttagcc ttcccacctc tatacagtct 4200 gataacggac cagcctttat tagtcaaatc agccaagcag tttttcaggc tcttagtagg 4260 tttcagtgaa aactttatat cccttacggt cctccgtctt caagaaaagt agaacggact 4320 aaagatcttt taaaaacaca gctcaccaag ctcagccacc aacttaaaag gactgacaat 4380 acttttacca cttttgcttc tcagaattca ggcctgtcct caatgctaca aggtacagcc 4440 catttaagct cctgtataga cgctcctttt tattaggccc cagtctcatt tgacaccaga 4500 ccaacttaga ctgtgcccca aaaaaacttg tcatccctac tatcttttgt ccagtcatac 4560 tcctattcac cgttctcaac tactcataca tgccctgctc ttgtttacac tgccggttta 4620 cactgtttct ccaagccatc acagctgata tctcctggtg ctatccccaa actgccactc 4680 taaactcttg aagtaaataa ataatctttg ctggcaggac tatgctgaat ctccttaggc 4740 actctctaat cagatgtcct aggtcctccc aattcttaga ccttttatac ctgtttttct 4800 ccttctctta ttccatttag tttctcaatt catccaaaac cgtatccagg ccatcaccaa 4860 tcattctata caacaaatgt ttcttcttac atccccacaa tatcaccctt taccacaaga 4920 cctcccttca gcttaatctc tcccactcta ggttcccacg ccgcccctaa tcctgcttga 4980 agcagcccta agaaacattg cccattctct ctccatacca cccccacaaa aattttcgcc 5040 gccccaacac ttcaacacta ttttgttttg tcttattaat ataagaaggc aggaatgtca 5100 ggcctctgag cccaggccag gccatcgcat cccctgtgac ttgcacgtat acatccagat 5160 ggcctaaagt aactgaagat ccacaaaaga agtaaaaaca gccttaactg atgacattcc 5220 accgtgtgat ttgttcctgc cccaccctaa ctgatcaatg tactttgtaa tctcccccac 5280 ccttaagaag gttctttgta attctcccca cccttgagaa tgtactttgt gagatccacc 5340 cctgcccacc agagaacaac cccctttgac tgtaattttc cattaccttc ccaaatccta 5400 taaaacggcc ccacccatat ctcccttcgc tgactctctt ttcggactca gcccacctgc 5460 acccaggtga aataaacagc catgttgctc acacaaagcc tgtttggtgg tctcttcaca 5520 cggacatgta tgaaa 5535 <210> 8 <211> 5575 <212> DNA <213> Homo sapiens <400> 8 gtcagacctc tgagcccaag ctaagccatc gcatcccctg tgacttgcac gtatacatcc 60 agatggcctg aagtaactga agatccacaa aagaagtaaa aatagcctta actgatgaca 120 ttccaccatt gtgatttgtt cctgccccac cctaactgat caatgtactt tgtaatctcc 180 cccaccctta agaaggttct ttttaattct ccccaccctt gagaatgtac tttgtgagct 240 ccacccactg tctgcaaaac attgctctta acttcagcgc ctatcccaaa acctataaga 300 actgatgata atccaccacc ctttgctgac tctcttttcg gactcagccc gcctgcaccc 360 aggtgaaata aacagccatg ttactcacac aaagcctgtt tggtggtctc ttcacacgga 420 cgtgcatgaa atttggtgcc gtgactcgga tcgggggacc tcccttggga gatcaatccc 480 ccgtcctcct gctctttgct ctgtgagaaa gatccaccta cgacctcagg tcctcagact 540 gaccagccca agaaacatct caccaatttg aaatccggta agcagcctct ttttactctc 600 ttctgcaacc tccctcacta tccctcaacc tctttctcct ttcaatcttg gcaccacatt 660 tcaatctctc ccttctctta atttcaattc ctttcatttt ctggtagaga caaaggggac 720 acgttttatc cgtggaccca aaactccggc gccggtcacg gactgggaag gcagccttcc 780 cttggtgttt aatcattgca aggatgcctc tctgattatt cacccacgtt tcaagggtgt 840 cagaccacac agggacgcct gccttggtcc ttcaccctta gcggcaagtc ccgcttttct 900 ggggaagggg caagtacccc aaccccttct ctccttgtct ctatcccttc tctgcttttc 960 tggggaaggg gcaagtaccc caaccccttc tctccgtgtc tctacccctt ctctccgtgt 1020 ctctacccct tctctgcctt tctgggggag gggcaagtac ccctcaaccc cttcttcacc 1080 cttagcggca agtcccgctt ttctaggggg caagaacccc caattcctta tttccacacc 1140 ccgacctctt atctctgtgc cccaattcct tatttctgca ccctgacctc ttatctctgt 1200 gccccaatcc cttatttctg caccccgacc tctcaactct gtgccccaat cccttatttc 1260 tgcaccccaa cctcttatct ctgtgcccca atcccttatt tccgtgccct gacccccctt 1320 cccgcttttc tggagggtaa gaacccccga aacccttccc tccatgtctc tacattctct 1380 tttctctagg tttgcctcct tcactatggg caaccttcca ccctccattc ctccttcttc 1440 tcccttagcc tgtgttctca agaacttaaa acctcttcaa ctcacacctg acctaaaacc 1500 taaatgcctt attttcttct gcaatgccgc ttgaccccaa tacaaactcg acagtagctc 1560 caaatagcca gaaaacggca ctttgaattt ttccatcctg caagatctaa ataattcttg 1620 tcgtaaaata ggcaaacggt ctgagttgcc tgacgtccag gcattctttt acacatcagt 1680 cccttcctag tctttgtccc caatgcaact cgtcccaaat cttccttctt tcccttccgc 1740 ctgtcccctc agtcccaacc ccaagcgtcg ctgagtcttt ctaatcttcc ttttctacag 1800 acccatctga cctttcccct cctccccagg ctgctcctcg ccaggccgag ctaggtccca 1860 attcttcctc agcctctgct cctccaccct ataatccttt tatcacctcg cctcctcaca 1920 cctggtccag cttacagttt cgttccgtga ctagccctcc cccacctgcc cagcaattta 1980 ctcttaaaaa ggtggctgaa gctaaaggca tagtcaaggt taatgctcct ttttctttat 2040 cccaaatcag aagcatttag gctctttttc atcaaatata aaaacccagc ccagttcatg 2100 gctcgtttgg cagcaaccct gagacgcttt acagccctag accctaaaag gtcaaaaggc 2160 cgtcttattc tcaatataca ttttactacc caatctgctc ccgacattaa ataaaactcc 2220 aaaaattgga atctggccct caaaccccac aacaggactt aattaacctc accttcaagg 2280 tgtacaataa cagaaaaaag ttgcaattcc ttgcctccac tgtgagacaa accccagcca 2340 catctccagc acacaagaac gtccaaacgc ctgaaccaca gcagccaggg gttcctccag 2400 aacctcctcc cccaggagct tgctacacgt gccggaaatc tggccactgg gccaaggaat 2460 gcccgcagcc cgggattcct cctaagctgc gtcccatctg tgtgggaccc cactgaaaat 2520 ccgactgttc aactcacctg gcagccactc ccagagcccc tggaactctg gcccaaggct 2580 ctctgactga ctccttccca gatcttctcg gcttagcagc tgaagactga cactgcccga 2640 ttgcctcgga agccccctaa accatcacgg atgccgagct tcaggtaact ctcacggtag 2700 aaggtagtaa gcgcgtcccc ttcttaatca atacggaggc tacccactcc acattacctt 2760 cttttcaaag gcctgtttcc cttgcctcca taactgttgt aagtattgac ggccaggctt 2820 ctaaacctct taaaactccc caactctggt gccaacttag acaatactct tttaagcact 2880 cctttttagt tatccccacc tgcccagttc ccttattagg ctgagacact ttaactaaat 2940 tatctgcttc cctgactatt cctggactac agccacatct cattgccgcc cttcttccca 3000 atccaaagcc tcctttgcgt cctcctcttg tatcccccta ccttaaccca caagtataag 3060 atacctctac tccctccttg gtgaccgatc atgtacccct taccgtctca ttaaaaccta 3120 atcaccctta ccccactcaa tgtcaagatc ccatcccaca gcacgcttta aaaggattaa 3180 agcctgttat cactcgcctg ctacagcatg gccttttaaa gcctatgaac tcttcttacc 3240 attcccccat tttacctgtc ctaaaaccag acaagcctta caagttagtt cagaatctgc 3300 gccttatcaa ccaaattgtt ctgcctatcc acccggtggt gccaaaccca tactcgatac 3360 ctccctctac tacccattat tctgttctag atctcaaaca tgctttcttt actattcctt 3420 tgcacccttc atcccagcct ctctttgctt tcacttagac tgaccctgac acccattagg 3480 ctcagcaaat tacctcggct gtactgccgc aaggcttcac agacagcccc cattacttca 3540 gtcaagccca aatttcatcc tcatctgtta cctatctcag cataattctc ataaaaatac 3600 acgtgctctc cctgctgatc gtgtctgatt aatctcccaa acctcagtcc cttacaaaat 3660 aacaactcct ttccttccta ggcatggtta gtgcagtcag aattcctaca caagagccag 3720 gacaggactg caccctgtag cctttctgtc caaacaactt gaccttactg ttttagccta 3780 gccctcatgt ctgtgtgcag cggctgccgc tgctttaata ctgttagagg ccctaaaaat 3840 cgcaaactat gctcaactca ctctctacat ttctcataac ttccaaaatc tattttcttc 3900 ctcatacctg acgcatatac tttctgctcc ccagctcctt cagctgtact cactctttgt 3960 taagtcccac aattaccatt gttcctggcc cggacttcaa tctggcctcc cacattattc 4020 ctgataccac acctgacccc catgactgta tctctctgat ccacctgata ttcaccccat 4080 ttccccatat ttccttcttt cctattcctc accctgatca cgcttgattt attgatggca 4140 gttccaccag gcctaatcgc cacacaccag caaaggcagg ctatgctata gtacaagtca 4200 ctagcccgcc tctcagaacc tctcatttcc tttccatcgt ggaaatctat cctcaaggaa 4260 ataacttctc agtgttccat ctgctattct actactcctc agggattatt caggccccct 4320 cccttcccta cacatcaagc tcaaggattt gcccccaccc aggactggca aattagcttt 4380 actcaacatg tcccgagtca ggaaactaaa atacctctta gtctaaatag acactttcac 4440 tgaataagta aaggcctttc ctacagggtc tgagaaggcc accacagtca tttcttccct 4500 tctgtcagac ataattcctc agtttagcct tcccacctca atacagtcta ataacagacc 4560 atcctttact agtcaaatca gccaagcagc ttttcaggct cttagtattc agtgaaacct 4620 ttatatccct tacggtcctc catcttcaag aaaaggagaa cggactaaag gtcttttaaa 4680 aacacacctc accaagctca gccaccaact taaaaaggac tggacaatac tttcaccact 4740 ttcgtttctc agaattcagg cctgtcctca gaatgctaca aggtacagcc catttaagct 4800 cctgtataga cgctcctttt tattaggccc cagtcccatt cgacaccaga ccaacttaga 4860 ctgtgcccca aaaaaacttg tcatccctac tatcttttgt ctagtcatac tcctattcac 4920 cattctcaac tactcataca tgccctgctc ttgtttacac tgctggttta tactgtttct 4980 ccaagccatc acagctgata tctcctggtg ctatccccaa actgccactc taaactcttg 5040 aagtaaataa ataatctttg ccggcaggac tatgctgaat ctccttaggc actctctaat 5100 cagatgtcct aggtcctccc aattcttaga ccttttatac ctgtttttct ccttctctta 5160 ttccatttag tttctcaatt catccaaaac catatgcagt ccatcaccaa tcattctata 5220 cgacaaatgt ttcttctaac atccccacaa tatcacccct taccacaaga cctcccttca 5280 gcttaatctc tcccactcta ggttcccacg ccgcccctaa tcccgcttga agcagccctg 5340 agaaacatcg cccattctct ctccattcca ccccccaaaa attttcgccg ccccaacact 5400 tcaacactat tttgttttat ttttcttatt ataagaaggc aggaatgtca ggcctctgag 5460 cccaagccaa gccatcgcat cccctgtgac ttgcacgtat acatccagat ggcctgaagt 5520 aactgaagat ccacaaaaga aataaaaata gccttaactg atgacattcc atcat 5575 <210> 9 <211> 6045 <212> DNA <213> Homo sapiens <400> 9 gtcaggcctc tgagcccagg ctaagccatc atatcccctg tgaccggcac ctatacatcc 60 agatggcctg aagcaactga agatccacaa aagaagtgaa aatagcctta actgatgaca 120 ttccaccatt gtgatttgtt tctgtcccaa cctaactgat caatgtactt ggtaatctcc 180 cccaccctta agaaggttct ttgtaattct ccccaccctt gagaatgtac tttgtgagat 240 ccaccccctg cctgcaaaac attgctccta acaccaccgc ctatcccaaa acctataaga 300 accatgataa tccaccaccc tttgctgacc cttttcggac tcagcccgcc tgcacccagg 360 tgaaataaac agccttgttg ctgacacaaa gcctgtttgg tggtctcttc acacggacgc 420 atgaaacaat atgtttactg cagcactact tatagttttt tattatttct ttatttattt 480 tttgagacgg agtctctctc tgttgctcag gctggagtgc agtggtgcga tcttggctca 540 ctgcaacctc cacctcctgg attcaagcga ttttcctgcc tcagcctccc gctgagtggt 600 aggcgcccgc caccactcct agcaaaattt tatttattta tttttatttt ttagtagaga 660 cagggtttcg tcatgttggc caggctggtc ttgaactcct gacctcaggt gatccacctg 720 tctcggcctc ccaaagtgct gggattacag gtgtgagcca ccgtgcctgg acactttttt 780 atttttaaca tcaaacatgt tttaaagtat tttaaaggac ctaatagaag aatagcctat 840 gtatttaccc atacataggt aaatgttctt cttcctttat tcctcctgtt tcaagtttcc 900 tttttatata attccccttc cgtctcaaaa aaattcctct aaaatctttg aaaggtaggg 960 taccagtgac aaattatctt agtttctctt cctctgagaa tgtctttatt tcacctcatt 1020 cctggagaat atttttacta gatctgaaat tccatattga accattcttt ccttcccaca 1080 atttaacaat agtcttccat tctcttctgt gtgccatggt ttctgatgtg aaatccgcag 1140 ttataggcca ggtgcggtgg ctcactcctg taatcccagc actttgggag gctgaggcgg 1200 gtggatcacc tgaggtcagt gtcaggcctc tgagcccagg ccaggccatc gcatcccctg 1260 tgacttgcag gtatacatcc agatggcctg aagtaactga agatccacaa aagaagtaaa 1320 aacagcctta actgatgaca ttccaccatt gtgatttgtt cctgccccac cctaactgat 1380 caatgtactt tgtaatctcc cccaccctta agaaggttct ttgtaattct ccccaccctt 1440 gagaatgtac ttggtgagat ccacccctgc ccaccagaga acaaccccct ttgactgtaa 1500 ttttccatta ccttcccaaa tcctataaaa cggccccacc cctatctccc ttcgctgact 1560 ctcttttcgg actcagcccg cctgcgccca ggtgaaataa acagccatgt tgctcacaca 1620 aagcctgttt ggtggtctct tcacacggat gcgcatgaaa tttggtgccg tgactcagat 1680 caggggacct cccttgggag atcaatcccc tgtcctcctg ctctttgctc cgtgagaaag 1740 atccacctat gacctcaggt tctcaaaccg accagcccaa gaaacatctc accaatttca 1800 aatctggtaa gcagcctttt actctcttct ccaatctccc tcactatccc tcagcctctt 1860 tctcctttca atcttggtgc tacacttcaa tctctccctt ctcttaattt caattccttt 1920 cattttctgg tagagacaaa agagacacgt tttatccgtg gacccaaaac tccggcgccg 1980 gtcacggact gggaaggcag ccttcccttg gtgtttaatc attgcaggga cacctctctg 2040 attatacact cacgtttcaa gggtgtcaga ccacgcaggg acgcctgcct tggtccttca 2100 cccttagcgg caagtcccgc ttttctgggg aaggggcaag taccccaacc ccttctctcc 2160 ttgtctctac cccttctctg cttttctggg gaaggggcaa gtaccccaac cccttctctc 2220 cttgtctcta ccccttctct gctttcctgg ggcaggggca agtacccctc aaccccttct 2280 ccttcgccct tagcggcaag tcccgctttc ctagggggca agaaaccccc aatcgcttat 2340 ttctgcaccc caacctctta tctctgtgcc ccaatccctt atttccgcac cctgacctct 2400 tatctctgtg ccccaatccc ttatttccgt gccccaaccc cttctctgct tttctggagg 2460 gcaagaaccc cccccctcct tctccgtgtc tctactcttt tctctgggct tgcctccttc 2520 actatgggta agcttccacc ttccattcct ccttcttctc ctttagcctg tgttctcaaa 2580 aacttaaaac ctcttccact cacacctgac ctaaaaccta aatgccttat tttcttctgc 2640 aatgccgctt gactccaata caagctcgac agtagttcca aatagctgga aaacggcact 2700 ttcaattttt ccatcctaca agatctaaat aattctcgtc gtaaaatggg caaacggtct 2760 gaggtgcctg acgtccaggc attcttttac acatcagtcc cttcctagtc tctgtgccca 2820 atgcaactcg tcccaaatct tccttctttc cctcccgcct gtcccctcag tcccaacccc 2880 aagcgtcgct gagtctttct aatgttcctt ttctacagac ccatctgacc tctcccttcc 2940 tccccaggct gctcctcacc aggccgagct aggtcccaat tcttcctcag cctccgctcc 3000 tgcaccctat aatcttttca tcgcctcccc tcctcacacc tgctctggct tacagtttcg 3060 ttccgtgact agccctcccc cacctgccca gcaatttact cttaaaaagg tggctggagc 3120 caaaggcata gtcaaggtta atgctccttt ttctttatcc caaatcagat agcgtttagg 3180 ctctttttca tcaaatataa aaatccagcc cagttcatgg ctcgctcggc agcaaccctg 3240 agacacttta cagccctaga ccctaaaagg tcaaaaggcc gtcttattct caatatacat 3300 tttattaccc aatctgttcc cgacattaaa taaaactcca aaaattaaat tccagccctc 3360 aaaccccaca acacgattta attaacctcg ccttcaaggt gtaccataat agaaaaaagt 3420 tgcaattcct tgcctccacg gtgagacaaa ccccagccac atctccagca cacaagaact 3480 tccaaacgcc tgaaccgcag cggccaggcg ttcccccaga acctcctccc ccaggagctt 3540 gctacaagtg ccagaaatct gaccaccagg ccaaggaatg cccgcagcct gggattcctc 3600 ctaagccgca tcccatctgt gtgggacccc actgaaaatc ggactgttca actcacctgg 3660 cagccactcc cagagcccct ggaactccgg cccaaggctc tctgactgac tccttcccag 3720 atcttctcgg cttagcggct gaagactgac actgcccgat cgcctcggaa gccccctaga 3780 ccatcacgga caccgagctt tgggtaactc tcacagtgga aggtaagtcc gtccccttct 3840 taatcaatat ggagtctacc cactccacat taccttcttt tcaaggcctg tttccctgcc 3900 tccataactg ttgtgggtat tgacggccaa gcttcaaaac ccctgaaaac tcccccactc 3960 ttgtgccaac ttggacaaca ctcttttatg cactcttttt tagttatccc cacctgccca 4020 gttcccttat caggccgaga tattttaacc aaattgtatg cttccctgac tattcctgga 4080 ttacagccgc atctcattgc cgcccttctc cccaacccaa agcctccttc gcatcttcct 4140 ctcatatccc ccaaccttaa cccacaagta tgggacatct ctactccttc cctggcaact 4200 gatcacatgc ccattaccat cccattaaaa cctaatcacc ctcaccccgc tcaacgccca 4260 tatcccatcc cacagcatgc tttaaaagga ttaaagcctg ttaccactcg cctgctacag 4320 catgggcttc taaaacctat aaactctcct tacaattccc ccattttacc tgtccaaaaa 4380 ctggataagt cttacagatt agttcaggat ctgcgtccta tcaaccaaat tgttttgcca 4440 tccaccctgt ggtgcccaac ccgtacactc ttttgtcctc aatccgttcc tccacaattc 4500 actattctgt tctccacctt aaagatgctt ttttcactat tcccctgcac ccctcgtccc 4560 agcctctctt tgctttcact tagactgacc ctgacaccca ttaggctcag caaattacca 4620 aggctgtact gctgcaaagc ttcacagaca gcccccatta cttcaatcaa gcccaaattt 4680 cttcctcatc tgttacttat ctcggcataa ttctcacaaa aacacacgtg ctttccctgc 4740 caatcgtgtc cgactgatct ctcaaacccc agcaccttct acaaaacaac aactcctttc 4800 cttcctaggc atggttagcg tggtcagaat tcttacacaa gagccaggac cacactctgt 4860 agcctttctg tccaaacaac ttgaccttac tgttttagcc tagccctcat gtctgcgtgc 4920 agcggctgct gctgctttaa tacttttaga ggccctcaaa atcacaaact ttatcagtcc 4980 tccaggccca agttgactcg ttagctgcag ttgtcctcca aaaccgccga ggccttgact 5040 gacttactgc tgagaaagga ggactctgca tattcttaaa tgaggagtgt tgtttttacc 5100 taaatcaatc tggcctggtg tatgacaaca taaaaaaact caaggataga gcccaaaaac 5160 ttgccaacca agcaagtaat tatgctgaac ccccttgggc actctctaat tggatgtcct 5220 gggtcctccc aattcttagt cctttaatac ccatttttct cctcctttta tttggacctt 5280 gtatcttccg tttagcttct caattcatcc aaaaccgtat ccaggccatc accaatcatt 5340 ctatacgaca aacgtttctt ctaacatccc cacaatgtca ccccttacca caagacctcc 5400 cttcagctta atctctccca ctctaggttc ccacgccgcc cctaatcccg ctcgaagcag 5460 ccctgagaaa catcgcccat tctctctcca taccaccccc caaaaatttt cgccgctcca 5520 acacttcaac actattttgt tttatttgtc ttattaatat aagaaggcag gaatgtcagg 5580 cctctgagcc caggccaggc catcgcatcc cctgtgactt gcaggtatac atccagatgg 5640 cctgaagtaa ctgaagatcc acaaaagaag taaaaacagc cttaactgat gacattccac 5700 cattgtgatt tgttcctgcc ccaccctaac tgatcaatgt actttgtaat ctcccccacc 5760 cttaagaagg tactttgtag tctcccccac ccttaagaag gttctttgta attctcccca 5820 cccttgagaa tgtacttggt gagatccacc cctgcccacc agagaacaac cccctttgac 5880 tgtaattttc cattaccttc ccaaatccta taaaatggcc ccacccctat ctcccttcgc 5940 tgactctctt ttcggactca gcccacctgc acccaggtga aataaacagc tttattgctc 6000 acacaaagcc tgtttggtgg tctcttcaca cggacgtgta tgaaa 6045 <210> 10 <211> 4776 <212> DNA <213> Homo sapiens <400> 10 gtcaggcctc tgagcccagg ccaggccatc gcaccccctg tgacttgcac gtatacatcc 60 agacggcctg aagtaactga agatccacaa aagaagtaaa aacagcctta actgatgaca 120 ttccaccatt gtgatttgtt cctgccccac cctaactgat caatgtactt tgtaatatcc 180 cccaccctta aggtactttg tagtctcccc cacccttaag aaggttcttt gtaattctcc 240 ccacccttga gaatgtactt tgtgagatcc acccctgccc accagagaac aacccccttt 300 gactgtaatt ttccattacc ttcccaaatc ctataaaatg gccccacccc tatctccctt 360 cgctgactgt cttttcggac tcagcctgcc tgcacccagg tgaaataaac agccatgttg 420 ctcacacaaa gcctgtttgg tggtctcttc acagggacac gcatgaaatt tggtgccgtg 480 actcggatcg ggggacctcc cttgggagat caatcccccg tcctcctgct ctttgctcca 540 tgagaaagat ccacctacga cctcaggtcc tcagaccgac cagcccaaga aacatctcac 600 caatttcaaa tccggtaagc ggcctctact cttctccaac ctccctcact atccctcaac 660 ctctttctcc tttcaatctt ggagccacac ttcaatctct cccttctctt aatttcaatt 720 cctttcattt tctggtagag acaaaagaga catgttttat ccgtgaaccc aaaactctgg 780 cgccggtcac ggactgggaa ggcagccttc ccttggtgtt taatcattgc agggatgcct 840 ctctgattat acactcacgt ttcaagggtg tcagaccacg cagggacgcc tgccttggtc 900 cttcaccctt agcggcaagt cccactttcc tggggcaggg gcaagtaccc ctcaacccct 960 tccccttcac cctcagcggc aagtcctgct ttcctggggc aggggcaagt acccctcaac 1020 cccttcccct tcaccctcag cggcaagtcc tgctttcctg gggcaggggc aagtacccct 1080 tccccttcac cctcagcggc aagtcctgct ttcctggggc aggggcaagt acccctcaac 1140 cccttctcct tcatccttag cagcaagtcc cgctttccta gggggcaaga accccccaat 1200 cacttatttc cacaccccaa cctcttatct ctgtgcccca atcccttatt tccgcaccct 1260 gacctcttat ttccatgccc caaccccttc tctgcttttc tggagggcaa gaacccccca 1320 ccccttctct gtgttgctac tcttttctct gggcttgcct ccttcactat gggtaagctt 1380 ccaccttcca ttcctccttc ttctccctta gcctgtgttc tcaaaaactt aaaacctctt 1440 caactcacac ctgacctaaa acctaaatgc cttactttct tctgcaatgc cgcttgactc 1500 caatacaagc tcgacagtag ttccaaatag ccggaaaacg gcactttcaa tttttccatc 1560 ctacaagatc taaataattc ttgtcgtaaa atgggcaaat ggtctgaggt acctgaagtc 1620 caggcattcc tttacacatc agtcccttcc tagtctctgt gcccagtgca actcgtccca 1680 aatctttctt ctttccctcc cgcctgtccc ctcagtccca accccaagtg tcgctgagtc 1740 tttctgatct tccttttcta cagacccatc tgacctctcc cctcctcgcc agcccaagct 1800 aggtcccaat tcttcctcag cctctgctcc tgcaccctgt aatcttttta tcgcctcccc 1860 tcctcacacc tggtcgggct tacagtttcg ttccgtgact agccctcccc cacctgccca 1920 gcaatttact cttaaaaagg tggctggagc caaaggcata gtcaaggtta atgctccttt 1980 ttctttatcc caaatcagat agcgtttagg ctctttttca tcaaatataa ccctgagatg 2040 cttcacagcc ctagacccta aaaggtcaaa aggcaatatt attctcaata tacattttat 2100 tacccaatct gctcccgaca ttaaatctcc aaaaattaaa ttccggccct caaaccccac 2160 aacagaattt aattaacttc accttcaagg tgtacaataa tagaaaaagt tgcaattcct 2220 tgcctccact gtgagacaaa ccccagccac atctccagca cacaagaact tccaaacgcc 2280 tgaaccacag cggccaggcg ttcctccaga acctccttcc ccaggagctt gctacaagtg 2340 ccagaaatct gaccaccagg ccaaggaatg catgcagccc aggattcctc ctaagccgtg 2400 tcccatctgt gcgggacccc actggaaatt ggactgttca actcacctgg cagccactcc 2460 cagagtccct ggaactctgg cccaaggctc tctgactgac tccttctcgg cttagcggct 2520 gaagactgat gctgcccgat cgcctcggaa gccccgtaga ccatcacgga cgccgagctt 2580 ccggtaactc tcacagtgga aggtaagccc gtccccttct taatcaatac ggaggctacc 2640 cgctccacat taccttcttt tcaagggcct gtttcccttg cctccataac tgtgggtatt 2700 gacagccagg cttctaaacc tcttaaaact cccccactct ggtgccaact tggacaacac 2760 tcctttatgc actctttttt agttattccc acctgcccag ttcccttatt aggccgagat 2820 attttaacca aattatctgc ttccctgact attcctggac tacagccgca tctcattgcc 2880 gaccttctcc ccaactcaaa gcctccttcg cgtcttcctc ttatatcccc ccaccttaac 2940 ccacaagtat gggacatctc tactccttcc atcaccctta ccccgctcaa cgccaatatc 3000 ccatcccaca gcatgcttta aaaggattaa agcctgttat cactcgcctg ctacagcatg 3060 ggcttctaaa acctataaac tcttacaatt cccccatttt acctgtccaa aaaccggata 3120 agtcttacag attagttcag gatctgcgtc ttatcaacca aattgttttg cctatccacc 3180 ctgtggtgcc caacccgtac actcttttgt cctcaatacg ttcctccaca actcactatt 3240 ctgttctcca tcttaaagat gcttttttca ctattcccct gcacccctcg tcccagcctc 3300 tctttgcttt cacttagact gaccctgaca ccccattagg ctcagcaaat tacctgggct 3360 gtactgctgc aaagcttcac agacagcccc cattacttca gtcaagccca gatttcttcc 3420 tcatctgtta cctatctcgg cgtaattctc gtaaaagcac acgtgctttc cctgccaatc 3480 gtgtccgact gatctctcaa accccagcac cttctacaaa acaacaactc ttttccttcc 3540 taggcatggt tagcgtggtc ggaattctta cacaagagcc aggaccacac cctgtagcct 3600 ttctgtccaa acaacttgac cttactgttt tagcctagcc ctcatgtctg cgtgcagcag 3660 ctgctgctgc tttaatactt ttagaggccc tcaaaatcac aaactttatc agtcctccag 3720 gcccaagttg actctttagc tgcagttgtc ctccaaaacc gccgaggcct tgacttactt 3780 actgctgaaa aaggaggact ctgcatattc ttaaatgagg agtgttgttt ttacctaaat 3840 cagtctggcc tggtgtatga caacataaaa aaactcaagg atagagccca aaaacttgcc 3900 aaccaagcaa gtaattacgc tgaaccccct tgggcactct ctaattggat gtcctgggtc 3960 ctcccaattc ttagtccttt aatacccatt tttctcctcc ttttattcag accttgtatc 4020 ttccatttag cttctcagtt catccaaaac tgtatccagg ccatcaccaa tcattctata 4080 tgacaaatgt ttcttctaac atccccacaa tatcatccct taccacaaga cttcccttca 4140 gcttaatctc tcccacttta tgttcccacg ccgccccaat cccacttgaa gcagccctga 4200 gaaacatcgc ccattctctc tccataccac cccccaaaaa ttttcgccgc tccaacactt 4260 caacactatt ttgttttatt tgtcttatta atataagaag gcaggaatgt caggcctctg 4320 agcccaggcc aggccatcgc atcccctgtg acttgcacgt atacatccag atggcctgaa 4380 gtaactgaag atccataaaa gaagtaaaaa cagccttaac tgatgacatt ccaccattgt 4440 gatttgttcc tgccccaccc taactgatca atgtactttg taatatcccc cacccttaag 4500 gtactttgta gtctccccca cccttaagaa ggttctttgt aattctcccc acccttgaga 4560 atgtactttg tgagatccac ccctgcccac cagagaacaa ccccctttga ctgtaatttt 4620 ccattacctt cccaaatcct ataaaatggc cccaccccta tctcccttcg ctgactgtct 4680 tttcggactc agcctgcctg cacccaggtg aaataaacag ccatgttgct cacacaaagc 4740 ctgtttggtg gtctcttcac acggacgcac atgaaa 4776 <210> 11 <211> 935 <212> DNA <213> Homo sapiens <400> 11 gtggggaaaa gaaagatcag attgttactg tgtctgtgta gaaaaggaag acataagaaa 60 ctccattttg atctgtacta agaaaaattg tttctgcttt gagatgttgt tagcctataa 120 ctttagcccc aactctgtgc tcacagaaac atgcgctgta atgaatcaaa gtttaatgga 180 tttagggctg tgcaggatgt gccttgttaa caatatgttt gcaggctgta tgcttggtag 240 aagtcatcgc cattctccat tctcgattaa ccagggacac aatgcacagc agaaagctgc 300 agggacctct gcccaagaaa gcctgggtat tgtccaaggt ttccccccca ctgagacagc 360 ctgagatatg gcctcatggg aagggaaaga cctgactgtc ccccagcccg acacctgtaa 420 agggtcggtg ctgaggagga atagtgaagg agggaggcct ctttgcagtt gagataagag 480 gaaggcttct gtctcctgct tgtccctggt aatggaatgt ctcggtgtaa aaagctgacc 540 attcccattc gttctattct gagataggag aaaaccgccc tgtggctgga ggtgagatat 600 gctggcagca atactgctct gttactcctt gctacactga gatgtttggg taaagagaaa 660 cataaatcta gcctacgtgc acatctgggc acagtacctt tccttgaact tattcgtgat 720 acagattcct ttgctcacat gtttccctgc tgaccttctt cccacctgtt gccctgctac 780 actcccctcg ctaagacagt aaaaataatg atcaataaat actgagggaa ctcagaggcc 840 agcgccggtg cgggtcctcc acatgctgag cgccggtcct gggcccactg ttctttctct 900 atactttgtc tctgtgtctt atttcttttc tcaaa 935 <210> 12 <211> 3184 <212> DNA <213> Homo sapiens <400> 12 gtcaggcctc tgagcccagg ccaggccatc gcatcccctg tgacttgcac gcatacatcc 60 agatggcctg aagtaactga agatccacaa aagaagtaaa aacagcctta actgatgaca 120 ttccaccatt gtgatttgtt cctgccccac cctagctgat caatgtactt tgtaatctcc 180 cccaccctta agaaggttct ttgtaattct ccccaccctt gagaatgtac tttgtgagat 240 ccacccctgc ccagcagaga acaaccccct ttgactgtaa ttttccatta ccttcccaaa 300 tcctataaaa cggccccacc cctatctccc ttccctgact ctcttttcgg acgcagcccg 360 cctgcgccca ggtgaaatac acagccatgt tgctcacaca aagcctgttt ggtgggctct 420 tcacacggac acgtatgcaa tttggtgccg tgactcggat cgggggacct cccttgggag 480 atcaatcccc tgtcctcctg ctctttgctc cgtgggaaag atccacctat gacctcaggt 540 cctcagaccg accagcccaa gaaacatctc accaatttca aatccggtaa gcggcctctt 600 tttactctct tctccaacct ccctcactat acccttagcg gcaagtcccg ctttcctggg 660 gcaggggcag gtacccctca accccttctc cttcaccctc agcggcaagt cccgctttcc 720 tggggcaggg gcaggtgccc ctcgacccct tctccttcac cctcagcggc aagtcccgct 780 ttcctggggc aggggcaggt gcccctcaac cccttctcct tcaccctcag cggcaagtcc 840 cgctttcctg gggcaggggc aggtgcccct cgaccccttc tccttcaccc tcagcggcaa 900 gtcccgcttt cctggggcag gggcaggtac ccctcgaccc tttctccttc accctcagcg 960 gcaagtcccg ctttcctggg gcaggacttg ccgctttcct ggggtaggga caagtacccc 1020 tgaacccctt ctccacatta cctgcttttc aagggcctgt ttcccttgcc tccataactg 1080 ttgtgggtat tgacagccag gcttctaaac ctcttaaaac tcccccactc tggtgccaac 1140 ttggacgaca ctcttttatg cactcttttt tagttatccc cacctgccca gttcccttat 1200 taggccgaga tattttaacc aaattatctg cttccctgac tattcctgga ctacagctgc 1260 aactcattgc tgcccttctc gctaacccaa agcctccttc gcgtctttct ttcatatccc 1320 cccaccttaa cccacaagta tgggacatct ctactccttc cctggcaact gatcacatgc 1380 ccattaccat cccgttaaaa cctaatcacc cttaccccac tcaacgccag tatcccatcc 1440 cacagcatgc tttaaaagga ttaaagcctg ttatcactcg cctgctacag catgggcttc 1500 taaaacctat aaactctcct taccattccc ccattttacc tgtcctaaaa ccagacaggg 1560 cttacaggtt agttcagaat ctgtgcctta tcaaccaaat tgttttgcct atccaccccg 1620 tggtgccaaa cccatatact ctcctatcct caatacctgc ctctacaacc cattattctg 1680 ttctggatct caaacatgct ttctttacta ttcctttgca cccttcatcc cagcctctct 1740 ttgctttcac ttggactgac cctgacaccc attaggctca gcaaattacc taggctgtac 1800 tgccgcaagg cttcacagac agcccccatt acttcaatca agcccaaatt tcttcctcat 1860 ctgttaccta tctcggcata attctcataa aaacacacgt gctctccctg ccaatcgtgt 1920 ccgactgatc tctcaaaccc cggcaccttt ctacaaaaca ataactcctt tccttcctag 1980 gcatggttag cgtggtcgta attcttacac aagagccagg accacaccct gtagcctttc 2040 tgtccaaaca acttgacctt actgttttaa cctagccctc atgtctgcgt gcagcggctg 2100 ccgctgcttt aatactttta gaggccctca aaatcacaaa ctttatcagt cctccaggcc 2160 caagttgact cttcagctgc agttgtcctc caaaaccgcc aaggccttga ctgacttact 2220 gctgaaaaag gaggactctg catattctta aatgaggagt gttgttttta cctaaatgca 2280 tctggcctgg tgtatgacaa cataaaaaaa ctcaaggata gagcccaaaa acttgccaac 2340 caagcaagta attacgctga acccccttgg gcactctcta attggatgtc ctgggtcctc 2400 ccaattctta gtcctttaat acccattttt ctcctccttt tattcggacc ttgtatcttc 2460 cgtttagctt ctcaattcat ccaaaaccgt atccaggcca tcaccaatca ttctatacga 2520 caaatgtttc ttctaacatc cccacaatat caccccttac cacaagacct cccttcagct 2580 taatctctcc cactctaggt tcccacgccg cccctaatcc cgctcgaagc agccctgaga 2640 aacatcaccc gttctctctc cataccaccc cccaaaaatt tccgccgctc caacacttca 2700 acgctatttt gttttatttg tcttattaat ataagaaggc aggaatgtca ggcctctgag 2760 cccaggccag gccatcacat cccgtgactt gcacgcatac atccagatgg cctgaagtaa 2820 ctgaagatcc acaaaagaag taaaaacagc cttaactgat gacattccac cattgtgatt 2880 tgttcctgcc ccaccctaac tgatcaatgt actttgtaat ctcccccacc cttaagaagg 2940 ttctttgtaa ttctccccac ccttgagaat gtactttgtg agatccaccc ctgcccagca 3000 gagaacaacc ccctttgact gtaattttcc attaccttcc caaatcctat aaaacggccc 3060 aacccctatc tcccttccct gactctcttt tcggacgcag cccgcctgcg cccaggtgaa 3120 ataaacagcc atgttgctca cacaaagcct gtttggtggg ctcttcacac ggacgcgcat 3180 gaaa 3184 <210> 13 <211> 5641 <212> DNA <213> Homo sapiens <400> 13 tcaggcctct gagcccaagc caagccatca catgccctgt gacttacatg tatatgccca 60 gatggcctga agtaactgaa gaatcacaaa caaagtgaat atgccctgcc ccaccttaac 120 tgatgacatt ccaccacaaa agaagtgtaa atggccagtc cttgccttaa gtgaggacat 180 taccttgtga aagtcctttt cctagctcac cctggctcaa aaagcacccc cactgagcac 240 cttgagaccc ccactcctgc ccaccagaga acaaaccccc tttgactgta attttccttt 300 acctacccaa atcctataaa acggccccac ccttatctcc cttcgctgac tctcttttcg 360 gactcagccc acctgcaccc aggtgaaata aacagcttta ctgctcacac aaagcctgtt 420 tggtggtctc ttcacacgga cgcgcatgaa atttggtgcc atgactcgga tcaggggacc 480 tcccttggga gatcaatccc ccgtcctctt gttctttgct ccatgagaaa gatccaccta 540 tgacctcagg tcctcagacc gaccagccca agaaacatct caccaatttc aaatccggta 600 agtggcctct ttttactctc ttctccaacc tccctcacta tccctcaacc tctttctcct 660 ttcaatcttg gtgccacact tcaatctctc ccttctctta atttcaattc ctttcaattc 720 ctttggtaga gacaaaggag acgcatttta tccgtggacc caaaactccg gcgccggtca 780 cggactggga aggcagcctt cccttggtgt ttaatctttg cagggacgcc tgcctcggtc 840 cttcaccctt agcggcaagt cctgctttcc tggggcaggg gcaagtaccc ctcaacccct 900 tcttcaccct cagcggcaag tcctgctttc ctggggcagg ggcaagtacc cctcaacccc 960 ttctccttca ccctcagcgg caagtcccgc tttcctaggg ggcaagaacc ccccaatcgc 1020 ttatttccac accccaacct cttatctctg cgccccaatc ccttatttcc gtgccccaac 1080 cccttctctg cttttctgga gggcaagaac cccccacccc tactccatgt ctctactctt 1140 ttgtctgggc ttgcctcctt cactatgggc aagcttccac cttccattcc tccttcttct 1200 cccttagcct gtgttctcaa aaacttaaaa cctcttcaac tcacacctga cctaaaacct 1260 aaatgcctta ttttcttctg caatgccact tgaccccaat acaaactcga cagtagttcc 1320 aaatagccag aaaatggcac tttcaatttt tccatcctgc aagatctaaa taattcttgt 1380 cgtaaaatgg gcaaatgttc tgaggtgcct gacgtccagg cattctttta cacatctgtc 1440 ccttcctagt ctctgtgccc agtgcaactc gtcccaaatc ttccttcttt ccctcccgcc 1500 tgtcccctca gtcccaaccc caagcgtcgc tgagtctttc taatcttcct tttctacaga 1560 cccatctgac ctctcctctc ctcgccagct caagctaagt cccaattctt cctcagcctc 1620 cgctcctgca ccctgtaatc tttttatcgc ctcccctcct cacacctggt ctggcttaca 1680 gtttcattcc gtgactagcc ctcccccacc tgcccagcaa tttaccctta aaaaggtggc 1740 tggagccaaa ggcatagtca agtttaacgc tcctttttct ttatcccaaa tcagatagcg 1800 tttaggctct ttttcatcaa atataaaaac ccagcccagt tcatggctag tttggcagca 1860 accctgagag gctttacagc cctaaaccct aaaaggtcaa aaggccgtct tattctcaat 1920 atacatttta ttacccaatc tgctcccgac attaaataaa actccaaaaa ttaaattccg 1980 gccctcaaac cccacacagg atttaatgaa cctcgccttc aaggtgtaca ataatagaaa 2040 aaagttgcaa ttccttgcct ccactgtgag acaaacccca gccacatctc cagcacacaa 2100 gaacttccaa acgcctgaac cgcagcggcc aggcgttcct ccagaacctc ctccaggagc 2160 ttgctacaag tgccagaaat ctgaccacca ggccaaggaa tgcccgcagc ccaggattcc 2220 tcctaagcca tgtcccatct gtgcaggacc ccactggaaa tcggactgtt caactcacct 2280 ggcagccact cccagcgccc ctggaactct ggcccaaggt tctctgactg actccttctc 2340 ggcttagcgg ctgaagactg atgctgcccg atcacctcag aagcccccta gaccatcacg 2400 gacgccgagc ttcaagtaac tctcacagtg gagggaagtc cgtccccttc tttatcaata 2460 cggaggctac ccactccaca ttaccttctt ttcaagggcc tgtttccctc gcctccataa 2520 ctgttgtggg tattgatgac caggcttcta aacctcttaa aactccccaa ctctggtgcc 2580 aacatagaca atactctttt aagcactcct ttttagttat ccccacctgc ccagttccct 2640 tattaggcca aaacacttta actaaattat ctgcttccat gactattcct agactacagc 2700 tatatctcat tgctgccctt cttcccaatc caaagcctcc tttgcgtcct cctcttgtat 2760 cccccccacc ttaacccaca agtataagat acctctactc cctccttggt gagactgatc 2820 acgcacccct taccatctca ttaaaaccta atcaccctta ccccgctcaa cgccaatatc 2880 ccatcccgca gcacgcttta aaaagattaa agcttgttat cactcgcctg ctacagcatg 2940 gccttttaaa gcctataaat tctccttaca attcccccat tttacctgtc ctaaaaccag 3000 acaagcctta caagttagtt caggatctgc accttatcaa ccaaattgtt ttgcctatcc 3060 accccatggt gccaaaccca tatactctcc aatcctcaat acctgcctct actacccatt 3120 attctgttct ggatctcaaa catgctttct ttactattgc tttgcaccct tcatcccagc 3180 ctctctttgc tttcacttgg actgaccctg acacccatca agctcagcaa attacctagg 3240 ctgtactgcc gcagagcttc acagacagcc cccattactt cagtcaagcc caaatttctt 3300 cctcatctgt tacctatctc ggcataattc tcataaaagc acacgtgctc tccctgccaa 3360 tcgtgttcga ctgatctctc aaacccaagc atcttctaca aaacaacaac tcctttcctt 3420 cctaggcatg gttagcgcgg tcagaattct tacacaagag ccaggaccac accctgtagc 3480 ctttctgtcc gaacaacttg accttactgt tttagcctag ccctcatgtc tgcgtgcagc 3540 ggctgctgct gctttaatac ttttagaggc cctcaaaaat cacaaactat gctcaactca 3600 ctctctacag ttctcataac ttccaaaatc tattttcttc ctcatacctg acgcaaatac 3660 tttctgcttc ccggctcctt cagctgtact cactctttgt tgagtctccc acaattaccg 3720 ttgttcctgg cccagacttc aatctggcct cccacattat tcctgatacc acacctgacc 3780 cccatgacta tctctctgat ccacctgaca ttcaccccat ttccccaaat ttccttcttt 3840 cctgttcctc acgctgatca cgcttgattt attgatggcg gttccaccag gcctaatcgc 3900 cacacaccag caaaggcagg ttatgctata gtacaagcca ctagcccgcc tcttagaacc 3960 tctcatttcc tttccatcgt ggaaatctat cctcaaggaa ataacttctc agtgttccat 4020 ctgctattct actactcctc agggattatt caggccccct cccttccctg cacatcaagc 4080 tcgaggattt gccccaccca ggactggcaa attagcttta ctcaacatgc cctgagtcag 4140 ataactaaaa tatctcttag tctaggtaga tactttcact ggataggtag aggcctttcc 4200 tacagggtct gggaaggcca ccgcagtcat ttcttccctt ctgtcagaca taattcctca 4260 gtttagcctt cccacctcaa tacagtctga caacagatga gcctttatta gtcaaatcag 4320 ccaagcaggt tttcaggctc ttagtattca gtgaaacctt tacatccctt acggtcctcc 4380 gtcttcaaga aaagtagaat ggactaaagg tcttttaaaa acacacctca ccaagctcag 4440 ccaccaactt aaaaaggact ggacaatact tttaccactt tcccttctca gaattcaggc 4500 ctgtcctcag aatgctacag ggtacagccc atttaagctc ctgtatagat gctccttttt 4560 attaggcccc agcctcattc cagacaccag accaacttag actgtgcccc aaaaaacttg 4620 tcatccctac tatcttctgt ctagtcatac tcctgttcac cgttctcaac tactcataca 4680 tgccctgttc ttgtttacac tgccggttta cactgttttt ccaagccatc acagctgata 4740 tctcctggtg ctatccccaa actgccactc ttaactcttg aagtaaataa ataatctctg 4800 ctggcaggac tatgctgaat ctccttaggc actctctaat cagatatcct gagtcatccc 4860 aattcttaga ccttttatat ctgttttact ccttctctta ttccatttag tttctcaatt 4920 catccaaaac catatccagg ccatcaccag tcattctata tgacaaatgt ttcttctaac 4980 atccccacaa tctcacccct taccacaaga cctcccttca gcttaatctc tcccactcta 5040 ggttcccacg cctcccctaa tcccgcttga agcagccctg agaaacatca cccattctct 5100 ctccatacca ccccccaaaa atttccgccg ctccaacact tcaacactat tgtgttttat 5160 ttttcttatt aatataagaa gtcaggaata tcaggcctct gagcccaagc caagccatcg 5220 catcccctgt gacttgcacg tatatgccca gatggcctga agtaactgaa gaatcacaaa 5280 agaagtgaat atgccctgcc ccaccttaac tgatgacatt ccaccacaaa agaagtgtaa 5340 atgcccgggt cttgccttaa gtgatgacct taccttgtga aagtcctttt cctagctcat 5400 cctggctcaa aaatcacccc cactgagcac cttgagaccc ccactcctgc ccgccagaga 5460 acaaaccccc ttggactgta attttccttt acctacccaa atcctataaa agggctccac 5520 ccttatctcc cttcactgac tctcttttcg gactcagccc acctgcaccc aggtgaaata 5580 aacagcttta ctgctcacac aaagcctgtt tggtggtctc ttcacacgga cgcgcatgaa 5640 a 5641 <210> 14 <211> 5964 <212> DNA <213> Homo sapiens <400> 14 gtcacgcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac gtatacccag 60 atgacctgaa gtaactgaag aatcataaaa gaagtgaata tgccctgccc caccttaact 120 gatgacattc caccacaaaa gaagtgtaaa tggctggtcc ttgccttaag tgatgacatt 180 accttgtgaa agtccttttc ctagctcatc ctgactcaaa aagcacctcc actgggcacc 240 ttgcgacccc cactcctgcc cgccagagaa caaaccccct ttgactgtaa ttttccttta 300 cctacccaaa tcctataaaa cggccccacc cccatctccc ttcactgact ctatttttgg 360 actcagcctg cctgcgccca ggtgaaataa acagccatat tgctcacaca aagcctgttt 420 ggtggtctct tcacacggac acgcatgaaa tttggtgccg tgactcggat cgggggacct 480 cccttgggag atcaatcccc tgtcctcctg ctctttgatc catgagaaag atccacctat 540 gacctcaggt cctcagaccg accagcccaa gaaacatctc accaatttca aatccggtaa 600 gcagcctctt cttactctct tctccaactt ccctcactat ccctcaacct ctttctcctt 660 tcaatcttgg tgccacactt caatctctcc cttctcttaa tttcaattcc tttcattttc 720 tggtagagac aaaggagaca tgttttatcc gtggacccaa aactctggca ccggtcacgg 780 actgggaagg cagccttccc ttgttgttta atcattgcag ggacgcctct ctgattatta 840 acccacgttt caagggtgtc agaccatgca gggatgcctg ccttggtcct tcacccttag 900 cagcaattcc cgcttttctg gggaaggggc aagtacccca accccttctc tccttgtctc 960 taccccttct ctgcttttcc agggacaggg caagtacccc aaccccttct ctccttgtct 1020 ctaccccttc tcagcttttc ttggagaggg gcaagtaccc ctcaacccct tctccttcac 1080 ccttagcgac aagtcccgct tttctggggg aggggcaagt accactcaac cccttctcct 1140 tcactcttag tggcaagtcc cgcttttcta gaggaggggc aagtacccca acctcatatc 1200 tctgtgcccc aatcccttat ttccatgccc caacctcata tctctgcacc ccaatccctt 1260 atttccatgc cccaacctca tatctctgca ccccaatccc ttatttccac gccccgacct 1320 cttatttctg cgccccatcc cttatttccg tgccctgacc tcttatctct gagccccaac 1380 cccttttccc acttttctgg aaggtaagaa cccctgaacc ccttccttcc atttctctac 1440 tctctctttt ctctaggctt gcttccttca ctatgggaaa cttccaccct ccattcctcc 1500 ttctactccc ttggcctgtg ttctcaaaaa cttaaaacct caactcacac ctgacctaaa 1560 acctaaatgc cttattttct tctgcaatgt ctcttgaccc caatacaaac tcgacagtag 1620 ttccaaatag ccagaaaatg gcactttgaa tttttccatc ctgcaagatc taaataattc 1680 ttgttgtaaa ataggcaaat ggtctgaggt gcctgatgtc caggtattct tttacacatc 1740 agtcccttcc tagtctgtgc ccattgcaac tcgtcccaaa tcttccttct ttccctcccg 1800 cctgtcccct cagtaccaac cccaagcgtc actgagtctt tctaatcttc cttttctaca 1860 gacccatctg acctctccct tcctccccag gctgctcctt gccaggccga gctaggtccc 1920 aattcttcct cagcctctgc tcctccaccc tgtaatcctt tcatcacctc ccctcctcac 1980 acctggtccg gcttacagtt tcgttcagtg actagccctc cccctcctgc ccagcaattt 2040 actcttaaaa cggtggctgg agctaaaggc atagtcaagg ttaatgctcc tttttcttta 2100 tcccaaatca gaagcgttta ggatcttttt catcaaatat aaaaacccag cccagttcat 2160 gactcctttg gcagcaaccc tgagacactt tacagcccta gaccctaaaa ggtcaaaagg 2220 ccgtcttatt ctcaatatac attttattac ccaatctgct cccgacacta aataaaactc 2280 caaaaattaa attccagccc tcaaacccca caacaggatt taatgaacct cgccttcaag 2340 gtgtacaata atagaaaaaa gttgcaattc cttgcctcca ctgtgagaca aaccccagcc 2400 acatctccag cacccaagaa cttccaaacg cctgaaccac agcggccagg cgttcctcca 2460 gaacctcctc ccacaggagc ttgctacatg tgccggaaat ctggccactg ggccaaggaa 2520 tgcccgcagc ccgggattcc tcctaacctg tgtcccatct gtgtgggacc ccactgaaaa 2580 ttggactgtt caactcacct ggcagccact cccagaggcc ctggaactct ggcccaaggc 2640 tctctgactc cttcgcagat cttctcggct tagcggctga agactgacgc tgccggatcg 2700 cctcggaagc cccctagacc atcacggacg ccgagcttcc ggtaactctc acagtggaag 2760 gtaagcccgt ccccttctta atcaatacgg aggccaccca cgccacatta ccttcttttc 2820 aagggcctgt ttcccttgcc tccataactg ttgtggatat tgacggccag gcttctaaac 2880 ctcttaaaac tccccaactc tggtgccaac ttagacaata ctcttttaag cactcctttt 2940 tagttatccc cacctgccca gctcccttat taggctgaga cactttaact aaattatctg 3000 cttccctgac tattcctgga ctacagctat gtctcattgc cgcccttctt cccaatccaa 3060 agcctccttt gtgtcctcct cttgtatccc cccaccttaa cccacaagta taagatatct 3120 ctactccctc cttggcgacc ggtcatgcac cccttaccat ctcattaaaa cctaatcacc 3180 cttaccccac tcaacgccaa tatcccatcc cacagcacgc tttaaaaaga ttaaagcctg 3240 ttatcactcg cctgctaaag catggccttt taaaacctat aaactctcct tacaattccc 3300 ccattttacc tgtcctaaaa ccagacaagc cttacaattt agttcaggat ctgcgcctta 3360 tcaaccaaat tgttttgcct atccacccca tggcgccaaa cccatatact ctcctatcct 3420 caatacctgc ctctacaacc cattattctg ttctagatct caaacatgct ttctttacta 3480 ttcctttgca cccttcatcc cagcctctct tcactttcat ttggactgac cctgacaccc 3540 atcaagctca gcaaattacc taggctgtac tgctgcaaag gttcacagac agcccccatt 3600 acttcaatca agcccaaatt tcttcctcat ctgttaccta tctctgcata attctcataa 3660 aaacacacgt gctctccctg ccaatcgtgt ccgactgatc tctcaaaccc aagcaccttc 3720 tacaaaacga caactccttt ccttcctagg catggttagc gcggtcagaa ttcttacaca 3780 agagccagga caacaccctg taggctttct gtccaaacaa cttgacctta ctgttttagc 3840 ctagccctca tgtctgcatg cagcggctgc cactgcttta gtacttttag aggccctcaa 3900 aatcacaaac tgtgctcaac tcattctcta cagttctcct aacttccaaa atctattttc 3960 ttcctcatac ctgatggata tactttctgc ttcctggctc cttcagctat actcacactt 4020 tgttgagcct cccacaatta ccattgttcc tggcccagac ttcaatccgg cctcccacat 4080 tattcctgat accacacctg acccccatga ctatctctct gatccacctg acattcaccc 4140 cgtttcccca aatttccttc tttcctattc ctcaccctga tcatgcttga tttattgatg 4200 gcggttccac caggcctaat cgccacacac cagcaaaggc aggttttgct atagtacaag 4260 ccactagccc acctcttaga acctctcatt tcttttccat cgtggaaatc tatcctcaag 4320 gaaataactt ctcagtgttc catctgctat tctactactc ctcagggatt attcaggcct 4380 cctcccttcc ccacacatca agctcgagga attgccccac ccaggactgg caaattagct 4440 ttactccaca tgccctgagt cagaaaacta acatatctct tggtctaggt agacactttc 4500 actggatagg tacaagcctt tcctacaggg tctgagaagg ccaccgcagt catttcttcc 4560 attctgtcag acataattcc tcagtttagc cttcccacct caatacagtc tgataacaga 4620 tgagccttca ttagtcaaat gagccaagca gtttttcagg ctcttagtat tcagtgaaac 4680 ctttatatcc cttacggtcc tccatcttca agaaaagtag aaaggactaa tggtctatta 4740 aaaacacacc tcaccaagct cagccaccaa cttaaaaagg actggacaat acttttacca 4800 ctttcccttc tcagaattca ggcctgtcct tagaatgcta cagggtacag cccatttaag 4860 ctcttgtata gacgctcctt tttattaggc cccagtctca ttccagacac cagaccaact 4920 tggactgtgc cccaaaaaac ttgtcatccc tactatcttc tgtctagtca tactcctatt 4980 caccgttctc aactactcat acatgccctg ctcttgttta cactgctggt ttacactgtt 5040 tttccaagcc atcacagctg atatctcctg gtgctatccc caaactgcca ctcttaactc 5100 ttgaagtaaa taaataatct ttgctggcag gactatgctg aatctcctta ggcactctct 5160 aatcagatat cctgagtcat cccaattctt agacatttta tacctgtttt tctccttctg 5220 ttattccatt tagtttctca attcatccaa aaccgtatct aggccatcac caatcattct 5280 atatgacaaa tgtttcttct aacatcccca caatatcacc ccttaccaca agacctccct 5340 tcagcttaat ctctcccact ctaggttccc aagccacccc taatcccgct tgaaacagcc 5400 ctcagaaaca tcgcccattc tctctccata ccacccccca aaaattttcg ctgccccaac 5460 acttcaacat tattttgttt tatttttctt attaatatca gaaggcagga atgtcaggcc 5520 tctgagccca agccaagcca tcacatcccc tgtgacttgc acgtatatgc ccagatggcc 5580 tgaagtaact gaagaatcac aaaagaagtg aatatgccct gccccacctt aactgatgac 5640 attccaccgc aaaagaagtg caaatggcca gtccttgcct taagtgatga cattaccttg 5700 tgaaagtcct tttcctggct catcctggct caaaaagcac ccccactgaa caccttgcga 5760 cccccactcc tgcccgccag agaacaaacc ccctttgact gtaattttcc tttacctacc 5820 caaatcctat aaaacggccc cacccctatc tcccttcact gactctcttt tcggactcag 5880 cctgcctgca cccaggtgaa ataaacagcc atgttgctca cacaaagcct gtttggtggt 5940 ctcttcacac ggacgcgcat gaaa 5964 <210> 15 <211> 477 <212> DNA <213> Homo sapiens <400> 15 agaccactac tactcctgct gtcctcctcc ccctaccttg cctagttcac aagacaggag 60 gagagaaaaa gcaaaaagtt ggaaaaaaac aaaagtaaga taaatagcca gacaacctgg 120 gcgccaccac ctggccctag gagttaaaaa aagtaataat aataacatca acccctgacc 180 taaactgctt gtgttatctg taaattccag acactgtatg aaaaaagcat tgtgaaactt 240 tttttctgtt agctgttgca tgtagccccc agtcacgttt cccacgcttg cttgatgtat 300 cgcgaccatt ttgcgtggac cccttaaagt tgtaagcctt taaaaaggcc aaggatttct 360 tttttgggga gctgagctct taagacgcga gtctgctgac gctcctggct gaataaaaac 420 ctcttccttc tttaatctgg tgtctgagga gttttgtctg cggctcatcc tgctaca 477 <210> 16 <211> 6304 <212> DNA <213> Homo sapiens <400> 16 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac gtacacatct 60 agatggccgg ttcctgcctt aactgatgac attccgccac aaaaaaagtg aaaatggcct 120 gttcctgcct taactgatga cattatcttg tgaaattcct tctcctggct catcctggct 180 taaaagctct cctactgagc accttgtgac cccccactcc tgcctgccag agaacaaccc 240 ctctttgacg gtgattttcc tttacctacg caaatcttat aaaacggccc tacccctatc 300 tcccttcgct gactctcttt tcggactcag cccacctgca cccaggtgat taaagagctt 360 tattgctcac acaaagcctg tttggtggtc tcttcatatg gacgagagtg aaatctggtg 420 ccgtgacttg gatcagggga cctcccttgg gagatcaatc ccctgtcctg ctttttgttc 480 catgagaaag attcacctac gacctctggt cctcagacca accagcccaa ggaacatctc 540 accaatttta aatctggtaa gcggcctctt tttactctct tctccaacct ctctcactat 600 ccctcaacct ctttctcctt tcaatcttgg tgccacactt caatctctcc cttctcttaa 660 tttcagttcc ttttcttttc tagtagagac aaaggagacg cgttttatcc attgacccaa 720 aactccggtg ctggtcactg acttgggaag acagtcttcc cttggtgttt aatcacgtgg 780 ggatggctgc ctgattattc acccatgttt cagaggtgtc tgaccatgca aggacgcctg 840 ccttggtcct tcacccttag cggcaagtac cgcttttctg gagggcaaga aacccccaac 900 cccttctctc cgtgtctcta ccccttctcc gcttttctgg gaggcaagaa tcccccgacc 960 cttctctcca tgtctacccc ttctccactt ttctgcgggg caagaaaccc ccagcccctt 1020 ctccttcacc cttagcagca agtaccactt ttctagaggg caagaatccc ccaacccttc 1080 tctccgtgtc tctacccctt ctccactttt ctggggcgca agaacccccc accccttctc 1140 tctgtgtctc tactctctct tttctctggg cttgcctcct tcactatggg caagctcccg 1200 ccctccattc ccttcttctc ccttagcctg tgttcttaaa aacctaaaac ctcttcaact 1260 cacacctgac ctaaaaccta aatgcctttt cttctgcaat cctgcttgac cccaatacaa 1320 acttgacagt agttccaaat agccaaaaaa tggcagtttc aatttttcca tcctacaaga 1380 cctaaataat tcttgtcaca aaataggcaa acggtctgag gtgcctgacg tccaggcatt 1440 cttttacaca tcagtccctc cctagtctct gttcccagtg caactcatcc caagtcttcc 1500 ttctttccct cccgcctgtc ccctcagtcc caaccccacg cgtcgctgag tcttcctaat 1560 ctttcttttc tacagaccca tctgacttct cccctcctca ccaggccgag ctaggtcaca 1620 attcttcctc agcctccact cctccaccct ataatcattt tatcacctcc cctcctcaca 1680 cccggtccgg cttagtttcg ttccgcgact agccctcccc cacctgccca gcaatttcct 1740 cttaaaaagg tggctggagc taaaggcata gtcaaggtta atgctccttt ttctttatcc 1800 caaatcagat agtgtttagg cttttttcat caaataaaaa acgcagccca gttcatggct 1860 catttggcag caaccctggg atgctttaca gccctagacc ctaaaaggtc aaaaggccgt 1920 cttacactca atatacattt tattacccaa tccgctccgg acattaaata aaacttcaaa 1980 aattaaattc cagccctcaa accccacaac aggacttaat taacctcgcc ttcaaggtgt 2040 acaataataa agtagaggca gccaagtagc aatgtatttc tgagttgcaa ttccttgcct 2100 ccactgtgag acaaacccca gccatatctc cagcacacaa gaactccaaa cgcctgaact 2160 gcagctgctg gggttactct agaacctcct cccccaggag cttgctacaa gtgccagaaa 2220 tctggccact gggccaagga atgcctacag cccaggattc ctcctaagct gtgtcccatc 2280 tgtgcaggac cccactgaaa attggactgt tcaactgacc tggcagccac tttcagagcc 2340 cctggaactc tggcccaagg ctctctgact gactccttcc cagatcttct cagcttagcg 2400 gctgaagact gacactgccc aattgcctcg gaagcctacg ggaccatcac agatgctctg 2460 ggtaactctc acagtggaga gtaagtctgt ccccctctta atcaatacgg agcctaccca 2520 ttccacatta ccttcttttc aagggcctgt ttcccttgcc cccataaccg ttggaggtat 2580 tgacggccag gcttctaaac ctcttaaaac tccccaactc tggtgctaat ttagacagta 2640 ctcttttaag cactcctttt tagttatccc cacccgccca gttcacttat taggccgaga 2700 cacttaaact aaattatctg cttccctgcc tattcctggg ctacagccac acctcaatgc 2760 cgccttttcc cccagttcag agcctccttc acatcctccc tttgtatctc cccatcttaa 2820 cccacaagta taggacacct ctactccctc cttagcaact gatcatgcac cccttaccat 2880 cccattaaaa cctaatcact cttaccccgc tcaatgccaa tatcccatcc catggcatgc 2940 tttaaaagga ttaaagtctg ttatcactcg cctgctacag catggccttt taaagcctat 3000 aaactctcct tacaattccc caattttacc tgtcctaaaa ccagacaagg tttacaggtt 3060 agttcaggat ctgcgcctta tcaaccaaat tgttttgcct atccacccca tggtgccaaa 3120 cccatacact ctcctatcct caatacctcc ctccacaacc cattattctg ttctggatct 3180 caaacatgct ttctttacta ttcctttgca cccttcatcc cagcctctct tcgctttcac 3240 ttggactgac cctgacaccc atcaggttca gcaaattacc tgggctatac tgccgcaaag 3300 cttcacagac agcccccatt acttcagtca agcccaaatt tcttcctcat ctgttaccta 3360 tctcggcata attctcataa agacacgtgc tctccctgct gatcgtgtcc ggctaatctc 3420 ccaaacccca atcccttcta caaaacaaca actcctttcc ttcctaggca tggttagtgt 3480 ggtcagaatt cttacacaag agccgggacc acaccctgta gcctttctgt ccaacttgac 3540 cttactgttt tagcctagcc ctcatgtctg catgcagcgg ctgccgctgc tttaatactt 3600 ttagaggccc taaaaatcac aaactatgct caattcactc tctacagttc tcataacttc 3660 caaaatctat tttctttctc ccacctgatg catatacttt ctgctccctg gctccttcag 3720 ctgtactcac ttcttgttga gtctcccaca attaccattg ttcctggccc agacttcaat 3780 ccagcctccc acagtattcc agataccaca cctgaccccc atgactgtat ctctctgatc 3840 cacctgacat tcaccccatt tccccatatt tcctttcctg ttcctcaccc tgaacacatt 3900 tggtctattg atggcagttt caccaggcct aatcgccaca caccaccaaa ggcaggctat 3960 gctatagtac aagccaccag cccacctctt agaacctctc atttcctttc cattgtggaa 4020 atctatcctc aaggaaataa cttctcagtg ttccatctgc tattctacta ctcctcaggg 4080 attattcagt ccccctccct tccctacaca tcaagctcga gaatttgccc ccgcccagga 4140 ctggcaactc ttaactccct cttagagtgg atagatgatc tctgctggca ggggaccctc 4200 caatacttcc accctgatga agttctattg tttagtttta tactcactct tattatcatt 4260 cccattctta tgccaccctc tacctctccc cagctatctc caccatacta tcaactttac 4320 tcattctctc ctagccgttt ctaatccctc cttagcgaac aaccgctggc tttgcatttc 4380 cctttcttcc agtgcctaca cagctgtccc cgccttacat gcagactagg caacatctcc 4440 tgtctcccta tacctccgaa cttcctttaa cagccctcac ctttaccctc ctgaagaact 4500 catttacttt ctagacaggt ccagcaagac ctccccagac atttgacatc agcaagctgc 4560 caccctcctc cgcacttact taaaacacct ttctccttat atcaactcta ctccccacat 4620 atttggaccc ctcacaacac aaactactat tcctgtggct gctcctttat gtatctctcg 4680 tcaaagaccc attggaattc ccctgggtaa cctttcacct tctcgatgtt cctttactct 4740 tcatctccaa agccctcttc ttgtttactt atacccagcc ccgaaaataa cagtgaaagg 4800 ttggtcgtag acactcgacg ttttctcaca caccatgaaa atcgaacctc cccctctaca 4860 cagttacctc atcagttccc gttacaacct ctgacggctg ccgccctagc tggatcccta 4920 ggagtctagg tacaagacac ctttttcagc actccttctc atctttttag tttgcatctc 4980 cagttttgcc tcgcacaagg tctcttcttc ctctgtggat cctctaccta catgtgtcta 5040 cctgctaatt gggcaggtac atgcacacta gttttcctta ctcccaaaat tcaatttgca 5100 aataggaccg aagagctccc tgttcccctc tgacaccgac acgacaaaaa agagttattc 5160 cactaattcc cgtgcttgtc agtttaagac tttctgcctc cactattgct ctcagtattg 5220 gaatagcagg catttcaacc tctgtcacga ccttccatag cctctctaat gacttctctg 5280 ctagcatcac agacatccca caaactttat cagtcctcca ggcccaagtt gactctttag 5340 ctgcagttgt cctccaaaac cgccgaggcc ttgacttact cactgctgaa aaaggaggac 5400 tccgtatatt cttaaatgaa gagtgttgtt tttacctaaa tcaatctggc ctagtgtatg 5460 acaacataaa aaactcaagg atagagccca aaaacttgcc aaccaagcaa gtaattacgc 5520 tgcaccccct ggggcactct ctaattagat gtcctaggtc ctcccaattc ttagtccttt 5580 aatacctgtt tttctccttc tcttattctg tttagttttt caattcatac aaaaccatat 5640 ccaggccatc accaataatt ctacacgaca aaatgtttct tctaacaacc ccacaatatc 5700 accccttacc ataaaatctt ccttcagctt aatctctccc actctaggtt cccatgctgc 5760 ccctaatccc gcttgaagca gccctgagaa acatcgccca ttatctctcc ataccacccc 5820 caaaaatttc gctgtcccaa aactttacca ctatttcatt ttatttttct tattaatata 5880 agaagacagg aatgtcaggc ctctgagccc aagctaagcc atcatatccc ctgtgaggtg 5940 cacgtacaca tccagatggc tggttcctgc cttaactgat gacattccac cacaaaagaa 6000 gtgaaaatgg cctgttcctg ccttaactga tgacattatc ttgtgaaatt ccttctcctg 6060 gctcatcctg gctcaaaagc tcccctactg agcaccttgt gacccccact cctgcccact 6120 agagaacaac ccccctttga ctgtaatttt cctttaccta cccaaatctt ataaaacggc 6180 cctaccccat ctcccttcgc tgactctctt ttcggactca gcctacctgc atccaggtga 6240 ttaaaaagct ttattgctca cacaaagcct gtttggtggt ctcttcacac ggacgagagt 6300 gaaa 6304 <210> 17 <211> 5710 <212> DNA <213> Homo sapiens <400> 17 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac gtatgccccc 60 agatggcctg aagtaactga agaatcacaa aagaagtaaa aaggccctgc cccaccttaa 120 ctgatgacat tccaccattg tgatttgttc ctgccccacc ttaactgagt gattaaccct 180 gtgaatttcc ttctcctggc tcagaagctc ccccactgag caccttgtga ccccccgccc 240 ctgcccacca gagaacaacc ccctttgact gtaattttcc attaccttcc caaatcctat 300 aaaacggccc cacccctatc tcccttcgct gactctcttt ttggactcag cccacctgca 360 cccaggtgaa acaaccagcc atgttgctca cacaaagcct gtttggtggt ctcttcacac 420 agacgcgcat gaaatttggt ggatcagggg acctcccttg ggagatcaat cccctgtcct 480 cctgctcttt gctccatgag aaagctccac ctaccacctc aggtcctcag actgaccagc 540 ccaagaaaca tctcaccaat ttcaaatccg gtaagtggcc tctttttact ctcttctcca 600 acctccctca ctatccctca acctctttct cctttcaatc ttggtgccac acttcaatct 660 ctcccttctc ttaatttcaa ttcctttcat tttctggtag agacaaagaa gacacgtttt 720 atccgtggac ccaaaactcc agcactggtc atggactggg aagacagact tcccttggtg 780 tttaatcatt gcagagacac ctctctgatt attcacccac atttcaaagg tgtcagacca 840 catagggagg cctgccttgg tcctccaccc ttagcggcaa gtcccgcttt tctgggggag 900 gggcaagtat cccaacccct tctctccatg tctctacccc ttctctgctt ttctggggga 960 ggggcaagta cccctcaacc ccttctcctt cacccttagc ggcaagtcct gcttttctgg 1020 gggaggggca agtaccccaa ccccttcttc agtgtctcta ccccttctct gcttttctgg 1080 gggaggggca agtacccctc aaccccttct ccttcacctt tagtggcaag tcccgctttt 1140 ctagggggca agaaccccca atcccttatt tctgtacccc aacctcttat ctctgtgccc 1200 caatccctta tttccatgcc ccaccccccc ttcccacttt tctggagggt aagaaccccc 1260 aaaacccttc cctccgtgtc tctacaccct cttttctctg ggtttgcctc cttcactatg 1320 ggcaaccttc catcctccat tcctccttct tctcccttag cctgtgttct caagaactta 1380 aaacctcttc aactcacacc tgacctaaaa cctaaatgcc ttattttctt ctgcaatgac 1440 gcttaacccc aatacaaact cgacatagtt ccaaatagcc agaaaacggc actttcaatt 1500 tttccatcct acaagatcta aataattctt gtcgtaaaat gggcaaatgg cctgaggtgc 1560 ctgacgtcca ggcattcttt tacacatcag tcccttccta gtctctgtgc ccagtgcaac 1620 tcatcccaaa tcttccttct ttccctcccg cctgtcccct cagtcccaac cccaagcatc 1680 gctgagtctt tctaatcttc cttttctaca gacccatctg acctctcccc tcctcgccag 1740 gccgagctag gtcccaattc ttcctcagcc tccgctcctc taccctataa tctttttatc 1800 gcctcccctc ctcacacctg gtccggctta cagtttcgtt ccgtgactag ccctccccca 1860 cctgcccagc aatttattct taaaaaggtg gctggagcca aaggcatagt caaggttaat 1920 gctccttttt ctttatccca aatcagaagc gtttaggctg tttttcatca aatataaaaa 1980 tccagcccag ttcacggctc gtttggcagc aaccctgaga cgctttacag ccctagaccc 2040 taaaaggtca aaaggccatc ttattctcaa tatacatttt actacccaat ctgctctgga 2100 cattaaactc caaaaattag aatctggccc ccaaacccca caacagggct taaataacct 2160 caccttcaag gtgtacaata atagaaaaaa gttgcaattc cttgcctcca ctgtgagaca 2220 aaccccagcc acatctccag cacacaagaa cttccaaacg cctgaaccgc agcggccagg 2280 cgttcctcca gaacctcctc ccccaggagc ttgctacatg tgccggaaat ctggccactg 2340 ggccaaggaa tgcccgcagc ctgggattcc tcctaagcca tgtcccatct gtgtgggacc 2400 ccactgaaaa tcggactgtt caactcacct ggcagccact cccagagccc ctggaactct 2460 ggcccaaggc tctctgactg actccttccc agatcttctc agcttagcgg ctgaagactg 2520 acactgcctg atcgcctcgg aagcccccta gaccatcaag gacgccgagc ttcaggtaac 2580 tctcacagtg gaaggtaagc ccatcccctt cttaatcaat acggaggcta cccactccac 2640 attaccttct tttcaatggc ctgtttccct tgcctccata actgttgtgg gtattgatgg 2700 ccaggcttct aaacctctta aaactcccca gctctggtgc caacttagat aatactcttt 2760 taagcattcc tttttagtta tccccacctg ccctgttccc ttattaggct gagacacttt 2820 aactaaatta tctgcttccc tgactattcc tggactacag ctatatctca ttgccgccct 2880 tctccccaat ccaaagcctc ctttgcgtcc tcctcttgta ttcccccacc ttaaccctca 2940 agtataagat acctctactc cctccttggc gaccgatcat gcacccctta ccatctcatt 3000 aaaacctaat cacccttacc ctgctcaatg tcaggatccc atcccacagc atgctttaaa 3060 aggattaaag cctgttatca ctcacctgct atagcatggc cttttaaagc ctataaactc 3120 tccttacaat tcccccattt tacctgtcta aaaccagaca agccttacaa gttagttcag 3180 gatctgcgcc ttatcaacca aattgttttg cctatccacc ccatggtgcc aaacccatat 3240 actctcctat cctcaatacc tccctctact acccattatt ctgttctgga tctcaaacat 3300 gctttttttt actattcctt tgcacccttc atcccagcct ctctttgctt tcacttagac 3360 tgaccctgac accagttagg ctcagcaaat tacctgggct gtactgctgc aaggcttcac 3420 agacagcccc cattacttca atcaagccaa aatttcatcc tcatctgtta cctatctcag 3480 cataattctc ataaaaacac atgtgctctc cctgctgatc gtgtccgatt aatctcccaa 3540 acctcaatcc cttacaaagc aactcctttc cttcctaggc atggttagcg cggtcagaat 3600 tcttacacaa gagccaggac cgcaccctgt agcctttctg tccaaacaac ttgaccttac 3660 tgttttagcc tagccctcat gtctgcgtgg agcggctgcc gctgctttaa tattttttga 3720 ggccctaaaa atcacaaact atactcaact cactctctac atttctcata acttccaaaa 3780 tctattttct tcctcatacc tgacgcatgt actttctgct ccccggctcc ttcagctgta 3840 ctcactcttt gttaagtccc acaattacca ttgttcctgg cccggacttc aatctggcct 3900 cccgcattat tcctgatacc acacctgacc cccatgactg tatctctctg atccacctga 3960 cattcacccc atttccccat atttccttct ttcctgttcc tcaccctgat cacgcttgat 4020 ttattgatgg cagttccacc aggcctaatc gccacacacc agcaaaggca ggctatgcta 4080 tagtacaagc cactagcccg cctcttaaaa cctctcattt tctttccatc atagaaatct 4140 atcctcaagg aaataacttc tcagtgttcc atctgctatt ctactactcc tgaaggatta 4200 ttcaggcccc ctcccttccc tacacatcaa gctcgaggat ttgcccccgc ccagtactgg 4260 caaattagct ttactcaaca tgccccgagt cacaaaaact aaaatacctc ttagtctaag 4320 tagacacttt cactagataa gtagaggcct ttcctacagg gtctgagaag gccaccacag 4380 tcatttcttc ccttctgtca gacataattc ctcagtttag ccttcccacc tctatacagt 4440 ctgataacag accagccttt attagtcaaa tcagccaagc attttttcag gctcttagta 4500 ttcagtgaca gactaatggt ctattaaaaa cacacttcac caagctcagc caccaactta 4560 aaaaggactg gacaatactt ttaccacttt cccttctcag aagtcagacc tgtcctcaga 4620 atcctacaag gtacagccca tttaagctcc tgtatatacg ctccttttta ttaggcccca 4680 gtctcattcc agacaccaga ccaacttaga ctgtgcccca aaaaacttgt catccctact 4740 atcttctgtc tagtcatact cctattctcc gttctcaact actcatacat gccctgctct 4800 tgtttacact gccagtttac actgtttctc caagccatca cagctgatat ctccttgtgc 4860 tatccccaaa ctgccactct taactcttga agtaaataaa taatctttgc tggcaggact 4920 atgctgaatc tccttaggca ctctaatcag atgtcctagg tcctcccaat tcttagacct 4980 tttccattta gtttttcaat tcatacaaaa catatccagg ccatcaccaa tcattctaca 5040 cgacaaatgt ttcttctaac aaccccacaa tatcacccct taccacaaga tcttccattc 5100 agcttaatct ctcccactct aggttcccac gccgccccta atcccgcttg aagcagccct 5160 gagaaacatc gcccattctc tctccatacc accccccaaa aatttttgcc gccccaacac 5220 ttcaacacta ttttgtttta tttttcttat taatataaga aggcaggaat gtctggcctc 5280 tgagcccaag ccaagccatc acgtcccctg tgacttgcac ctatatgccc agatggcctg 5340 aagtaactga agaatcacaa aagaagtgaa aaggccctgc cccgccttaa ctgatgacat 5400 tccaccattg tgatttgttc ctgccccacc ttaactgagt gattaaccct gtgaatttct 5460 ttctcctggc tcagaagctc ccccactgag caccttgtga ccccccccca cctcccctgc 5520 ccaccagaga acaaccccct ttgactgtaa ttttccatta ccttcccaaa tcctataaaa 5580 cggccccacc cccatctccc ttcgctgact ctcttttcgg actcagccca cctgcaccca 5640 ggtgaaataa acagccatgt tgctcacaca aagcctgttt ggtggtctct tcacatggac 5700 gcgcatgaaa 5710 <210> 18 <211> 410 <212> DNA <213> Homo sapiens <400> 18 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcat gtgcacatcc 60 agacggctgg ttcctacctt aactgatgat attccaccac aaaagaagtg aaaatggctg 120 gtccctgcct taactgatga cattaccttg tgaaattcct tctcctggct catcctggct 180 caaaagctcc cccactgaac accttgcaac ccccacccct ggccaccaga gaacaacccc 240 ctttgactgt aattttccat tacctaccca catcttataa aatggcccca tccctatctc 300 ccttcgctga ctcttttcgg actcagcccg cctgcaccca ggtgaaataa acagccttgt 360 tgctcacaca aagcctgttt ggtggtcgct tcacacagac acgagtgaaa 410 <210> 19 <211> 2187 <212> DNA <213> Homo sapiens <400> 19 tgcggtcaga attcttacac aagagccagg accgcaccct gtagcctttc tgtccaaaca 60 acttgacctt actgttttag cctagccctc atgtctgagt gcagcgtctg ccgctgcttt 120 aatactgtta gaggccctaa aaatcacaaa ctatgctcaa ctcacgctct acatttctca 180 taacttccaa aatctatttt cttcctcata cctaacgcat atactttctg ctccctggct 240 ccttcagctg tactcactct ttaagtccca caattaccat tgttcctggc ccggacttca 300 atctggcctc tcacattatt cctgatacca cacctgaccc ccatgactgt atctctctga 360 tccacctgat attcacccca tttccccata tttccttctt tcctgttcct caccctgatc 420 acgcttgatt tattgatggc agttccacca ggcctaattg ccacacacca gcaaaagcag 480 gctatgctat agtacaagcc actagcccgc ctctcagaac ctctcatttc ctttccatcc 540 tggaaatcta tcctcaagga aataacttca cagtgttcca tctgctattc tactactcct 600 cagggattat tcaggccccc tcccttccct acacatcaag ctcgaggatt tgcccccacc 660 caggactggc aaattagctt tactcaacat gcccaagtca ggaaactaaa atacctctta 720 gtctaaatag acactttcac tgaataagta aaggcctttc ctacagggtc tgagaaggcc 780 accgcagtca tttcttccct tctgtcagac ataattcctc agtttagcct tcccacctct 840 atacagtctg ataacagacc agcctttatt agtcaaatca gccaagcagt ttttcaggct 900 cttagtattc agtgaaacct ttatatccct tacggtcctc cgtcttcaag aaaagtagaa 960 cggactaaag gtcttttaaa aacacacctc accaagctca gccaccaact taaaaaggac 1020 tggacaatac ttttaccact ttcgcttctc agaattcagg cctgtcctca gaatgttaca 1080 aggtacagcc catttaagct cctgtataga cagacgctcc tttttattag gccccagtct 1140 catttgacac cagaccaact tagactgtgc cccaaaaaaa cttgtcatcc ctactatctt 1200 ttgtctagtc atactcctat tcaccattct caactactca tacctgccct gctcttgttt 1260 acactgccgg tttacactgt ttctccaagc catcacagct gatatctcct ggtgctatcc 1320 ccaaaccccc actctaaact cttgaagtaa ataaataatc tttgctggca ggactatgct 1380 gaatctcctt aggcactctc taatcagatg tcctaggacc tcccaattct tagacctttt 1440 atacctgttt ttctccttct cttattacat ttagtttttc aattcataca aaaccgtatc 1500 caggccatca ccaataattc taaatgacaa atgtttcttc taacaacccc acaatatcac 1560 cccttaccac aagatcttcc ttcagcttaa tctctcccac actaggttcc cacaccgccc 1620 ctaatcccgc ttgaagcagc cctgagaaac attgcccatt ctctctccat accaccccca 1680 aaaattttcg ctgccccaac acttcaacac tattttgttt catttttctt attaatataa 1740 gaaggcagga atgtcaggcc tctgagccca agccaagcca tcacatcaac tgtgacttgc 1800 acatatacgc ccagatggcc tgaagtaact gaagaatcac aaaagaagtg aaaaggccct 1860 gccccgcctt aactgatgac attccaccat tgtgatttgt tcctgcccca ccttaactga 1920 gtgattaacc ctgtgaattt ccttctcctg gctcagatgc tcccccactg agcaccttgt 1980 gacccccgcc cctgcccacc agagaacaac ccccctttga ctgtaatttt ccattacctt 2040 cccaaatcct ataaaacggc cccaccctta tctcccttca ctgactctct tttcggactc 2100 agcccgcctg cacccaggtg aaataaaaca gccatgttgc tcccacaaag cctgtttggt 2160 ggtctcttca cacggatgca catgaaa 2187 <210> 20 <211> 5899 <212> DNA <213> Homo sapiens <400> 20 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac gtatacatcc 60 agatggcctg aagtaactga agatccacaa aagaagtaaa aatagcctta acagatgaca 120 ttccaccatt gtgatttgtt cctgccccac cctaactgat caatgtactt tgtaatctcc 180 cccaccctta agaaggttct ttgtaattct ccccaccctt gacaatgtac tttgtgagat 240 ccaccctgcc cacaaaacat tgctcttaac ttcactgcct atcccaaaac ctataagaac 300 taatgataat ccaccaccct ttgctgactc tcttttcgga ctcagcccgc ctgcacccag 360 gtgaaataaa cagccatgtt gttcacacaa agcctgtttg gtggtctctt cacacggatg 420 cacatgaaat ttggtgccgt gactcggatc gggggacctc ccttgggaga tcaatacccc 480 gtcctcctgc tctttgctcc gtgagaaaga tccacctacg acctcaggtc ctaagaccga 540 ccagcccaag aaacatctca ccaatttcaa atccagtaag cggcctcttt ttactctctt 600 ctccaacttc cctcactatc cctcaacctc tttcttcttt caatcttggc gctacacttc 660 aatctctccc ttctcttaat ttcaattcct ttaattttct ggtagagaca aaagagacat 720 gttttatccg tggacccaaa actccagcgc ctgtcatgga ctgggaaggc agccttccct 780 ttgtgtttaa tcattgcagg gatgcctctc tgattataca cccatgtttc aagggtgtca 840 gaccacgcag ggacacttgc cttggtcctt cacccttagc ggcaagtccc gcttttcttg 900 ggaaggggca agtaccccaa tcccttctct ccttgtctct accccttctc tgcttctctg 960 gggaaggggc aagtacccca accccttctc tccttgtctc taccccttct ctgcttttct 1020 ggggaagggg caagtacccc tcaaccccct tctccttcac ccttagcggc aagtcccgct 1080 ttcctagagg gcaagaaccc ccccaatcgc ttatttctgc accccaacct cttatctctg 1140 tgctccaatc ccttatttcc acaccctgac cttttatctc tgtgccccaa tcccttattt 1200 ccatgcccca accccttctc tgcttttctg gagggcaaga accccccacc ccttctccgt 1260 gtctctactc ttttctctgg gcttgcctcc ttcactatgg gtaagcttcc accttccatt 1320 cctccttctt ctcccctagc ctgtgttctc aaaaacttaa aacctcttca actcacacct 1380 gacctaaaac ctaaatgcct tattttcttc tgcaatgccg cttgacccca atacaaactc 1440 aacagtagtt ccaaatagcc agaaaatggc actttgaatt tttccatcct gcaagatcta 1500 aataattctt gttgtaaaat aggaaaacgg tctgaggtgc ctgacatcca ggcattcttt 1560 tacacatcag tcccttccta gtctctgtgc ccagtgcaac tcatcccaaa tctttcttct 1620 ttccctcctg cctgtcccct cagtcccaac cccaagcgtc actgagtctt tctaatcttc 1680 cttttctaca gacccatctg acctctcccc tcctcgccag gccgagctag gtcccaattc 1740 ttcctcagcc tccgctcctc caccctataa tctttttatc acctcccctc ctcacacctg 1800 gtccggcttg cagttttgtt ccatgactag ccctccccca cctgcccagc aatttaatct 1860 taaaaagcca aaggcatagt caaggttaat gctccttttt ctttatccca aatcagatag 1920 cgtttaggct ctttttcatc aaatataaaa atccagctca gttcatgact tgtttggcag 1980 caaccctgag atgctttaca gccctagacc ctaaaaggtc aaaaggccat cttattctca 2040 atatacattg tattacccaa tctgctcccg acattaaata aaactccaaa aattaaattc 2100 cagccctcaa accccacaac aggatttaat taacctcacc ttcaaggtgt acaataatag 2160 aaaaaagttg caattccttg cctccactgt gagacaaacc ccagccacat ctccagcaca 2220 caagaacttc caaacgcctg aactgcagtg gccaggcgtt cctccagaac ctcctcccac 2280 aggagcttgc tacacgtgcc ggaaatccgg ccactgggcc aaggaatgcc cgcagcccag 2340 gattcctcct aagccgcgtc ccatctgtgt gggaccccac tgaaaatcag actgttcaac 2400 tcacctggca gccactccca gagcccctgg aactctggcc caaggctctc tgactgactc 2460 cttctcagat cttctcggct tagtggctga agactgacac tgcccgatcg cctcggaagc 2520 cccctaaacc atcacggatg ccgagcttcc ggtaactctc acagtggaag gtaagcccgt 2580 ccccttctta atcaatacgg aggctaccca ctccacatta ccttcttttc aagggcctgt 2640 ttcccttgcc tccataactg ttgtgggtat tgacggccag gcttctaaac ctcttaaaac 2700 tccccaactc tggtgccaac ttagacaata ctcttttaag cactcctttt tagttatccc 2760 cacctgccca gttcccttat taggctgaga cactaactaa attatctact tccctgacta 2820 ttcctggact acagctatat ctcattgcca cccttcttcc caatccaaag cctcctttgc 2880 atcctcctct tgtatccccc caccttaacc cacaaatatg agatacctct actccctcct 2940 tggcgactga tcatgcaccc cttaccatct cattaaaacc taatcaccct taccccactc 3000 aacgccaata tcccatccca cagcatgctt taaaaagatt aaagcctgtt atcactcgct 3060 tgctacagca tggcctttta aagcctataa actttcctta caattccccc attttacctg 3120 tcctaaaacc agacaagcct tacaagttag ttcaggatct gctccttatc aaccaaattg 3180 ttttgcctat ccaccccatg gtgccaaacc catatactct cctatcctca atacctgcct 3240 ctacaaccca ttattctgtt ctagatctca aacatgcttt ctttaccatt cctttgcacc 3300 cttaatccca gcctctcttc actttcactt ggactgaccc tgacacccat caagctcagc 3360 aaattaccta ggctgtacgg ctgcaaagct tcacagacag cccccattac ttcaatcaag 3420 cccaaatttc ttcctcatct gttacctatc ttggcataat tctcataaaa acacacgtgc 3480 tctccctgcc aatcgtgtct gactgatctc tcaaacccca gcaccttcta caaaacaaca 3540 actcctttcc ttcctaggca tggttagtgc agtcagaatt cttacacaag agccaggacc 3600 gcaccctgta gcctttctgt ccaaacaact tgaccttact gttttagcct agccctcatg 3660 tctgcgtgca gtggctgccg ctgcattaat acttttagag gccctcaaaa tcacaaacta 3720 tgctcaactc actctctaca gttctcataa cttccaaaat ctattttctt cctcatacct 3780 gacgcatata ctttctgctt cccagctcct tcagctgtac tcactctttg ttaagtccca 3840 caattaccat tgttcctggc ccagacttca atctggcctc ccacattatt cctgatacca 3900 cacctgaccc ccatgactgt atctctctga tccacctgat attcacccca tttccccata 3960 tttccttctt tcctgttcct caccctgatc acgcttgatt tattgatggc agttccacca 4020 ggcctaatcg ccacacacca gcaaaggcag gctatgctat agtacaagcc actagcccgc 4080 ctctcagaac ctctcatttc ctttccatcg tggaaatcta tcctcaagga aataacttct 4140 cagtgttcca tctgctattc tactacccct cagggattgt tcaggcctcc tccctttcct 4200 acacatcaag ctcgaggatt tgcccctgcc caggactggc aaattgactt tactcatatg 4260 cctcgagtca gaaaactaaa atatctgtta gtctgggtag acaccttgac tggatgggta 4320 gaggccttcc ccacagggtc tgagaaggcc accacagtca tttcttccct tctgtcggac 4380 ataattcctc ggtttggcct tcccacctct atacagtctg ataacggacc agcgtttact 4440 agccaaatta cccaagcagt ttctcaggct cttggtattc agtggaacct tcatatccct 4500 taccatcctc aatcttcagg aaaggtggaa cggactaatg gtcttttaaa ggcacacctc 4560 accaagctca gcctccaact taaaaaggat tggacagtac ttctacctct tgctcttctc 4620 agaatcagag cctgtcctcc agatgctaca gggtacagtc catttgaact tttataggga 4680 tgcactttct tgcttggccc taacctcatc cagacaccag ccctctaggc gactatcttc 4740 cagtcctcca gcaggctaga cagcaaattc gccaggctgc taatcttctc ttgcctactc 4800 cagatcccca gccatatgaa gacaccctag ctggatgatc agttcttgtt aagaatctga 4860 cccctcaaac tctacaacct cgatggaccg gaccctactt agtcatctat agtaccccga 4920 ctgccatccg cctgcaggat cctccccact ggtttcacca ttccagaata aagctgtgtc 4980 cattggacag ctagcctaat ccctcctctt cctcctggaa gtcgcaagta ctttccccta 5040 cttcccttaa actcactcgt atttctgaag aacagtaata acacttatga gcctaataca 5100 tcccttcatt ctattagatc ttttcgtcct taccctactt tttgcaacag ggctttacga 5160 agccaccccc accacttaga ctgtgcccca aaaaaacttg tcatccctac tatctttttt 5220 ctagtcatac tcctattcac cgttctcaac tactcataca tgccctgctc ttgtttacac 5280 tgccggttta cactgtttct ccaagccatc acagctgata tctcctggtg ctatacccaa 5340 actgccactc taaactcttg aagtaaataa ataatctttg ctggcaggac tatgctgaat 5400 ctccttaggt actctctaat cagatgtcct aggtcctccc aattcttaga ccttttatac 5460 ctgtttttct ccttctctta ttccatttag tttctcaatt catccaaaac cgtatccagg 5520 ccatcgccaa tcattctata caacaaatgt ttcttcttac atccccacaa tatcacccct 5580 taccacaaga cctcccttca gcttaatctc tcccattcta ggtttccacg ccaccccaat 5640 cccgcctgaa gcagccctga gaaacatctc ccattctctc tccataccac cccccaaaaa 5700 tgttcaccgc cccaacactt caacactatt ttgttttatt tttcttatta atataagaag 5760 gcaggaatgt cacgcctctg agcccaagcc aagccatcgc atcccctgtg tgacttgcac 5820 gtatacatcc agatggcctg aagtaactga agatccacaa aagaagtaaa aatagcctta 5880 actgatgaca ttccaccat 5899 <210> 21 <211> 5191 <212> DNA <213> Homo sapiens <400> 21 gtcaggcctc tgagcccaag ccaagccatc gcatctcctg tgacttgcac ctatacgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aaggccctgc cccgccttaa 120 ctgatgacat tccaccattg tgatttgttc ctgccccaac ttaactgaat gattaaccct 180 gggaatttcc ttctcctggc tcagaagctc ccccactgag caccttgtga cccccgcccc 240 tgcccaccag agaacaaccc cctttgactg taattttcca ttaccttccc aaatcctata 300 aaacggcccc acccctatct ccctttgctg actctctttt cggactcagc ccacctgcac 360 ccaggtgaaa taaacaacca tgttgctcac acaaagcctg tttggtggtc tcttcacacg 420 gacgcacatg aaatttggtg ccgtgactcg gatcggggga cctcccttgg gagatcaatc 480 ctccgtcctc ctgctctttg ctccatgaga aagatccacc tacgacctca ggtcctcaga 540 ctgatcagcc caagaaacat ctcaccaatc tcaaatccgg taagtggcct ctttttactc 600 tcttctccaa cctccctcac tatccctcaa cctctttctc ctttcaatct tggcgccaca 660 cttcaatctc tcccttctct taatttcaat tcctttcatt ttctggtaga gacaaaggag 720 acacgtttta tccgtggacc caaaactccg gcgccggtca cggactggga aggcagcctt 780 cccttggtgt ttaatcattg cagggacacc tctctgatta tacactcaca tttcaagggt 840 gtcagaccac acagggacgc ctgccttggt ccttcaccct tagtggcaag tcccgctttt 900 ctggggaagg gtcaagtacc ccaacccctt ctcttgtctc taccccttct ctgcttttct 960 ggggcagggg caagtacccc tcaacccctt ctccttcacc cttagcggca agtcccgctt 1020 tcctaggggg caagaacccc ccaatccctt atttccacac cccaacctct tatctctgcg 1080 ccccagtccc ttatttccac gccccaacct cttgtctctg cgccccaatc ccttatctct 1140 gcgccccaat cccttatttc cacaccccaa cctcttatct ctgcgcccca gtcccttatt 1200 tccacgcccc aacctcttat ctctgcgtcc caatccctta tttccacgcc ccaacctctt 1260 atctctgcgc cccaatccct tatctctgcg ccccaatgcc ttatttccgc gccccgaccc 1320 ccccctcccg cttttctgga aggtaagaac ccccgaaccc cttccctccg tgtctctacg 1380 ctctcttttc tctgggcttg cctccttcac tatgggcttg cctccttcac tatgggcaag 1440 cttccacctt ccattcctcc ttcttctccc ttagcctgta ttcttaagaa cttaaaacct 1500 cttcaactct cacctgacct aaaatctagg cgtcttattt tcttctgcaa tgccgcttga 1560 ccccaataca aactccacag tagttccaaa tagccggaaa acggcacttt caatttttcc 1620 atcctacaag atctaactaa ttcttgtcgt aaaatgggca aatggtctga gatgcctgac 1680 gtccaggcat tcttttacac atcagtccat tcctagtctc tgtgcccaat gcaactcgtc 1740 ccaaatctcc cgcctgtccc ctcagtccca accccaagcg tcgctgagtc tttctaatct 1800 tccttttcta cagacccatc tgacctctcc cctcctcgcc tggccaagct aggtcccaat 1860 tcttcctcag cctccactcc tccaccctat aatcctttta tcgcctcccc tcctcacacc 1920 tgctccggct tacagtttca ttccgtgact agccctcccc cacctgccca gcaatttact 1980 cttaaaaagg tggctggagc taaagacata gtcaaggtta atgctccttt ttctttatcc 2040 cagatcagat agcgtttagg ctctttttca ccaaatataa aaacccagtt catggctcgt 2100 ttggcagcaa ccctgaggcg cttcacagcc ccagacccta aaaggtcaaa aggccgtctt 2160 attctcaata tacattctat tacccaatct gctcccgaca ttaactccaa aaattggaat 2220 ctggccctca aaccccacag caggacttaa ttaacctcac cttcaaggtg tacaataaca 2280 gaaaaaagtt gcaattcctt gcctccactg tgagacaaac cccagccaca tctccagcac 2340 acaagaactt ccaaacgcct gaactgcagc agccaggcgt tcctccagaa cctcctcccc 2400 caggagctta ctacaagtgc cagaaatctg gccaccaggc caaggaatgc ctgcagccca 2460 ggattcctcc taagccgtgt cccatctgta cgggacccca ctggaaatcg gactgttcaa 2520 ctcacctggc agacactccc agagcccctg gaactctgac ccagggctct ctgactgact 2580 ccttcttggc ttaccggctg aaaactgacg ctgcctgatc gcctcggaag ccccgtagac 2640 catcacggac gccgagcttt aggtaactct cacagtggaa ggtaagtccg tccccttctt 2700 aatcaatatg gaggctaccc actccacatt accttctttt caagggcctg tttcccttgc 2760 ctccataact gttgtgggta ttgacagcca ggtttctaaa cttcttaaaa ctccccaact 2820 ctggtgccaa cttagacaac actcttttat gcactctttt ttagttatct ccacctgccc 2880 agttccctta ttaggccgag atattttaac caaatgatct gcttccctga ctattcctgg 2940 actacagcca catctcattg ctgcccttct tcccaatcca aagcctcctt tgcgtcctcc 3000 tcttgtatcc cccaccttaa cccacaagta taagatacct ctactccctc cttggtgacc 3060 gatcatgcac cccttaccat ctcattaaaa cctaatcacc cttaccccgc tcaatgccaa 3120 tatcccatcc cacagcatgc tttgaaagga ttaaagcctg ttatcactcg cctgctacag 3180 catggccttt taaagcctat aaactctcct tacaattccc ccattttacc tgtcctaaaa 3240 ccagacaagc cttacaagtt agttcaggat ctatgcctta tcaaccaaat tgttttgcct 3300 atccacccta tgatgccaaa cccatatact ctcctatcct caatacctcc ctccacaatc 3360 cattattctg ttctggatct caaacgtgct ttctttacta ctcctttgta cctgtcatcc 3420 cagcctctct tcgctttcac ttggactgac cctgacactc atcaggttca gcaaattacc 3480 tgggctgtac tgccgcaagg cttcacagac agcccccatt acttcagtca agcccaaatt 3540 tcatcctcat ctgttaccta tctcggcata attctcgtaa aaacacacga gctctccctg 3600 ctgatcgtgt ctgattaatc tcccaaacct caatccctta caaaacaaca aactcctttc 3660 cttcctaggc atggttaatg cagtcagaat tcttacacaa gagccaggac cgcaccctgt 3720 agcctttctg tccaaacaac ttgaccttac tgttttagcc tagccctcat gtctgcgtgc 3780 agcggctgcc gctgctttaa tacttttaga ggcctttcct acaaggtctg agaaggccac 3840 cgtagtcatt tcttcccttc tgtcagacat aattcctcag tttagccttc ccacctctat 3900 acagtctgat aacagaccag cctttattag tcaaatcagc caagcatttt ttcaggctct 3960 tagtattcag tgacagacta atggtctatt aaaaacacac ctcaccaagc tcagccacca 4020 acttaaaaag gactggacaa tacttttacc actttccctt ctcagaagtc agacctgtcc 4080 tcagaatgct acaaggtaca gcccatttaa gctcctgtat agacgctcct ttttattagg 4140 ccccagtctc attccagaca ccagaccaac ttcgactatg cccccaaata acttgtcatc 4200 cctactatct tccgtctagt catactccta ttcaccattc tcaactactc atacatgccc 4260 tgctcttgtt tacactgccg gtttacactg tttctccaag ccatcacagc tgatatctcc 4320 tcgtcctatc cccaaactgc cactcttaac tcttgaataa ataatctttg ctggcaggac 4380 tatgctgaac ctccataggc actctctaat tagatgtcct aggtcctccc aattcttagt 4440 ccttttatac ctgtttttct ccttctctta ttccacttag tttttcaatt catacaaaac 4500 cgtatccagg ccatcaccaa tcattctata cgacaaatgt ttcttctaac aaccccacaa 4560 tatcacccct taccacagat ctcccttcag cttaatctct cccactctag gttcccacac 4620 cgcccctaat cctgcttgaa gcagccctga gaaacatcac ccattctctc tccataccac 4680 cccccaaaaa ttttcgccgc cccaacactt caacactatt ttgttttatt tttcttatta 4740 atagaagaag gcaggaatgt caggcctctg agcccaagcc aagccatcgc atcccctgtg 4800 atttgcacct atacgcccag atggcctgaa gtaactgaag aatcacaaaa gaagtgaaaa 4860 ggccctgccc cgccttaact gacgacattc caccattgtg atttgttcct gccccaactt 4920 aactgagtga ttaaccctgg gaatttcctt ctcctggctc agaagctccc ccactgagca 4980 ccttgtgacc cccgcccctg cccaccagag aacaaccccc tttgactgta attttccatt 5040 accttcccaa atcctataaa acggccccac ccctatctcc cttcgctgac tctcttttcg 5100 gactcagccc acctgcaccc aggtgaaata aacaaccatg ttgctcacac aaagcctgtt 5160 tggtgttctc ttcacacgga cgcgcatgaa a 5191 <210> 22 <211> 5854 <212> DNA <213> Homo sapiens <400> 22 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac atatacgccc 60 agatggcctg aagtaactga agaagcacaa aagaagtgaa aaggccctgt cccgccttaa 120 ctgatgacat tccaccatta tgatttgttc ctgccccacc ttaactgagt gattaaccct 180 gtgaatttcc ttctcctggc tcagaagctc ccccactgag caccttgtga cccctgcccc 240 tgcccaccag agaacaaccc cctttgactg taattttcca ttaccttccc aaatcctatg 300 aaacggcccc attcctatct cccttcactg actctctttt cggactcagc ccgcctgcac 360 cgaggtgaaa taaacagcca tgttgctcac acaaagcctg tttggtggtc tcttcacacg 420 gacttgagtg aatttggtgc tgtgactcgg actgggggac ctccgttggg agatcaatcc 480 cccgtcctcc tgctctttac tccatgagaa agatccacct atgacctcag gtcctcagac 540 caaccagccc aagaaacatc tcaccaattt caaatccagt aagtggcctc tttttactct 600 cttctccatc ttccctcact atccctcaac ctctttctcc cttcaatctt ggggtcacac 660 ttcaatctct cccttctctt aatttcaatt cctttcattt tctggtagag acaaaggaga 720 cacgttttat ccatggaccc aaaactccgg cgccggtcac ggactgggaa ggcagacttc 780 ccttggtgtt taatcattgc agggacacct ctctgattat tcacccacat ttcaaaggtg 840 tcagaccaca cagggatgcc tgccttggtc cttcaccctt cgcggcaagt cctgcttttc 900 tgggggaggg gcaagtaccc ctcaacccct tctccttcac ccttagcggc aagtcccgct 960 tttctggagg aggggcaagt accccaaccc cttctctccg tgtctctacc ccttctctga 1020 ttttctgggg caagggcaag aacccctcaa ccccttctcc ttcccctcag tggcaagtcc 1080 cgcttttcta ggggaggggc aagtacccca accccttctc tccgtgtctc taccccttct 1140 ctgcttttct ggaggagagg caagtacccc aacctcatat ctctgcaccc cgatccctta 1200 tttccacacc ctgacctcgt atctctgcgc cctgacccct tctctgcttt tctggaggac 1260 aagaaacccc caccccttct ctgtgtctct actcttttct ctgggcttgc ctccttcact 1320 atgggcaagc ttccaccttc cattcctcct tctcccttag cctgtgttct taagaactta 1380 aaacgtcttc aactgtcacc tcacctaaaa tctaagtgtc ttattttctt ctgcaatgcc 1440 gcttgacccc aatacaaact cgacagtagt tccaaatagc cggaaaacag cactttcaat 1500 ttttccatcc tacaagatct aaataattct tgttgtaaaa tgggcaaatg gtctgaggtg 1560 gctgacatcc aggcattctt tcacacatca gtcccttcct agtctctgtg cccagtgcaa 1620 ctcatcccaa atcttccttc tttccctccc gcctgtcccc tcagtcccaa ccccaagcgt 1680 cgctgagtct ttctaatctt ccttttctac agacccatct gacctctccc ctcctcacca 1740 ggccaagcta ggtcccgatt cttcctcagc ctccgctcct ccaccctata atctttttat 1800 cgcctcccct cctcacacct ggtccagctt acaatttcgt tccatgagta tccctccccc 1860 acctgcccag caatttactc ttaaaaacgt ggctggagcc aaaggcatag tcaaggttaa 1920 tgctcctttt tctttattcc aaatcagaag cgtttaggct ctttttcatc aaatataaaa 1980 acccagccca gttcatggct cattcggcag caaccctgag acgctttaca gccctagacc 2040 ctaaaaggtc aaaaggccat cttattctca atatatattt tattacccaa tccgctcccg 2100 acattaaata aaactcccaa agttggaatc tggccctcaa accccacaac aggacttaat 2160 taacctcacc ttcaaggtgt acaataataa aaaaaaagtt gcaattcctt gcctctactg 2220 tgagacaaac cccagccaca tctccagcac acaagaactt ccaaacgcct gaaccgcagc 2280 agccaggcgt tcctccagaa cctcctcccc caggagcttg ctacaagtgc cagaaatctg 2340 accaccaggc caaggaatgc ctgcagccca ggattcctcc taagccgtgt cccatctgtg 2400 cgggacccca ctggaaatcg gactgttcaa ctcacctggc agccactccc agagcccctg 2460 gaactctggc ccaaggctct ctgactgact ccttctcggc ttagcagctg aagactgaca 2520 ctgcccgacc acctcgaaag ccccgtagac catcacagac gccgagcttc aagtaactct 2580 cacagtgcaa ggtaagtccg tccccttaat caatatggag gctacccact ccacattacc 2640 ttcttttcaa ggtcctgttt cccttgcctc cgtaactgtt gtaggtattg acggccaggc 2700 ttctaaacct cttaaaactc cccaactctg gtgccaactt agacaatact cttttaagca 2760 ctccttttag ttatccccac ctgcccagtt cccttattag gccgagacac tttaaattat 2820 ctgcttccct gactattcct ggattacagc tgcatctcat tgccgccctt cttcccaatc 2880 caaagcctcc tttgcatcct cctcttgtat tcccccacct taacccacaa gtataagata 2940 cctctactcc ctccttggcg actgatcatg caccccttac catctcctta aaacctaatc 3000 acccttaccc cactcaatgc caatatccca tcccacagca tgctttgaaa ggattaaagc 3060 ctgttatcac tcgcctgcta cagcatggcc ttttaaagcc tataaactct ccttacaatt 3120 cccccatttt acctgtccta aaaccagaca agccttacaa gttagttcag gatctatgcc 3180 ttatcaacca aattgttttg cctatccacc ctatggtgcc aaacccatat actctcctat 3240 cctcgatacc tccctccaca atccattatt ctgttctgga tctcaaaaat gctttcttta 3300 ctattccttt gcacccatca tcccagcctc tctttgcttt cacttggact gaccctaaca 3360 cccattaggc tcagcaaatt acctgggctg tactgcccca aggcctcaca gacagccccc 3420 attacttcag tcaagcccaa atttcatcct catctgttac ctatctcagc ataattattc 3480 ataaaaacac aggtgttctc cctgttgatt gtgtccgatt aatctcccaa acctcaattc 3540 cttacaaaac aacaactcct ttccttccta ggcatggtta atgtggtcag aattcttaca 3600 caagagccag gaccgcaccc tatagccttt ctgtccaaac aacttgacct tactgtttta 3660 gcctagccct catgtctgcg tgcagcggct gccgctgctt taatactttt agaggcccta 3720 aaaatcacaa actatgctca actcactctc tacatttctc ataacttcca aaatctattt 3780 tcttcctcat acctgatgca tatactttct gctccccggc tccttcagct gtactcactc 3840 tttgttaagt cccacaatta ccattgttcc tggcccggac ttcaatctgg cctcccacat 3900 tattcctgat accacacctg acccccatga ctgtatctct ctgatccacc tgacattcac 3960 cgcatttccc cgtatttcct tctttcctgt tcctcaccct gatcacgctt gatttattga 4020 tggcagttcc accaggccta attgccacac accagcaaag gcaggctatg ctatagtaca 4080 agccactagc ccacctctta gaacctctca tttcctttcc attgtagaaa tctatcctca 4140 aggaaataac ttctcagtgt tccatctgct attctactac tcctcaagga ttattcaggc 4200 cccctccctt ccctacacat caagcccggg gatttgcccc tgcccaggac tagcaaattt 4260 gctattctac tactcctcaa ggattattca ggccccctcc cttccctaca catcaagttc 4320 aaggatttgc ccctgcccag gactgtcata ttagctttac tcaacatgcc ccgagtcaca 4380 aaacctaaaa tacctcttag tctaagtaga cgctttcact agataggtag agacctttcc 4440 tacagggtct gaggccaccg cagtcatttc ttcccttctg tcagacataa ttcctcagtt 4500 tagccttccc acctctatac agtctgataa cagaccagtc tttattagtc aaatcagcca 4560 agcagttttt caggctctta atattcagtg aaacctttat atcccttata gtcctctgtc 4620 tttaagaaaa gtagaacaga ctaaaggtct tttaaaaaca cacctcacca agctcagcca 4680 ccaacttaaa aagaactgga caatactttt accactttcc cttctcagaa gtcagacctg 4740 tcctcagaat gctacaaggt acagcccatt taagttcctg tatagatgct cctttttatt 4800 aggccccagt ctcattccag acactggatc aacttagact gtgcccccaa aaaaacttgt 4860 catccctact attttctgtc tagtcatact cctattctcc attctcaact actcatacat 4920 gccctgctct tgtttacact gccagtttac actgtttctc caagccatca cagctgatat 4980 ctcctcgtgc tatccccaaa ccgccactct taactcttga agtaaataaa taatctttgc 5040 tggcaggact atgctgaatc tccttaggca ctctctaatc agatgtccta ggtcctccca 5100 attcttggac cttttatacc tgtttttctc cttctcttat tccatttagt ttttcaattc 5160 atacaaaact gtatccaggc catcaccaat aattcgaaat gacaaatgtt tcttctaaca 5220 accccacaat atcacccctt tctacaaaat cttccttcag cttaatctct cccactctag 5280 gttcccacgc tgccccaatc ccacttgaag cagccctgag aaacatcgtc cattctctct 5340 ccataccaac ccccaaaaat tttcgccacc ccaagacttc aacactattt tatttttctt 5400 attaatataa gaaggcagga atgtcaggcc tctgagccca agccaagcca tcgcatcccc 5460 tgtgacttgc acatatacac ccagatggcc tgaagtaact gaagaatcat aaaagaagtg 5520 aaaaggccct gccccgcctt aactgatgat attccaccat tgtgatttgt tcctgcccca 5580 ccttaactga gtgattaacc ctgtgaattt ccttctcctg gctcagaagc tcccccactg 5640 agcaccttgt gacccctgcc cctgcccacc agagaacaac cccctttgac tgtaattttc 5700 cattaccttc ccaaatccta taaaacggcc ccacccctat ctcccttcac ttgactcttt 5760 tcggactcag tccacctgca ccgaggtgaa ataaacagcc atgttgctca cacaaagcct 5820 gtttggtggt ctcttcacac ggactcgagt gaaa 5854 <210> 23 <211> 3769 <212> DNA <213> Homo sapiens <400> 23 aattgaagat ccacagaaga agtaaaaaca gccttaactg atgacattcc accattgtga 60 tttgttcctg ccccacccta actgatcaat gtactttgta atctccccca cccttaagaa 120 ggttctttgt aattctcccc acccttgaga atgtactttg tgagatccac ccctgcccac 180 cagagaacaa ccccctttga ctgtaatttt ccattacctt cccaaatcct ataaaacagc 240 cccaccccta tctcccttca cttgactctc ttttcagact cagcccacct gcacccaggt 300 gaaataaaca gctttattgc tcacacgaag cctgtttggt ggtctcttca cacggatgcg 360 catgaaattt ggtgccgtga cttggatcgg gggacctccc ttaggagatc aatcccccgt 420 cctcctgctc tttgctccgt gagaaagatc cacctacgac ctcaggtcct cagaccgacc 480 agcccaagaa acatctcacc aatttcaaat ctggtaagcg gcctcttttt actctcttct 540 ccattcctcc tccttctccc ttagcttctc caacctccct cactatccct caacctcttt 600 ctcctttcaa tcttggcgcc acacttcaat ctctcccttc tcttaatttc aattcctttc 660 attttctgga agagacaaaa gagacatgtt ttatccgtga acccaaaact ccggcgctgg 720 tcacggactg ggaaggcagc cttcccttgg tgtttaatca ttgcagggac gcctctctga 780 ttatacactc acgtttcaag ggtgtcagac cacgcaggga cgcctgcctt ggtccttcac 840 ccttagcggc aagtcccgct ttcctggggc aggggcaagt acccctcaac cccttctcct 900 tcaccctcag cggcaagtcc cgcttttctg gggcaggggc aagtacccct caaccccttc 960 cccttcacac ttagtggcaa gtcccgcttt cctggggcag gggcaagtac ccctcaacgc 1020 cttctccttc acccttagtg gcaagtcccg cttttctagg gggcaagaac ccccaaaccc 1080 cttccatctg tgtctctacg ctctcttctg tgggtttgct tccttcacta tgggcaacct 1140 tccaccctcc attcctcctt cttctccctt agcctgtgtg ctcaaaaagt taaaacctct 1200 tcaactcaca cctgacctaa aacctaaatg ccttattttc ttctgcaaca ccgcaaccgc 1260 ttggccccaa tacaaacttg acaatgtctc taaatggccg gaaaatggca ctttcgattt 1320 ctccatccta caagacctaa ataatttttg tcgaaaaatg ggcaaatggt ctgaggtgcc 1380 ttacgtccag gcatttttca cacttcgttc cctccctagt ctctgttccc aatgcgattc 1440 ctcccagatc ctcctccttt ccctcccgcc tgtcccctcg gtcccaaccc caagcgtcgc 1500 tgagtcttcc cagtcttcct tttctacaga cccatctgac ctttcccctc ctccccaagc 1560 tgcttgtcgc cagaccgagc taagtcccaa tacttcctca gcctccactc ctccacccta 1620 taatccttct atcacctccc ctcctcacac ctggtccggc ttacagttta gttccgcgac 1680 tagcgcttcc ccacctgccc aacaatttcc tcttagagaa gtggctggag ctgaaggcat 1740 agtcaaggta catgtacttt tttctctatc agacctctct cagatcagtc aatgtttagg 1800 ctctttctca tcagacccca ctaaatatat acaggaattc caatatctaa ctctgtccta 1860 caacttaacc tggagtgact taaatgtcat cctgacttct actctctccc cagatgaacg 1920 ggaaagtttt ttctctagcc caatctcgtg ctgataaccg ccggcttcat gagccagacc 1980 tccaggaagg cattagagca gttccccgag aggatcccca atggaactat caggcagatt 2040 ccccaggtac agctaggcga gattacatgg tttcctgcct agttgaaggg cttaaaaaag 2100 cagcttacaa agctgttaat tatgacaagc ttaaagaaac tacccgaggt aaagacgaaa 2160 acccagccca ggtcatggcc cacttagcag caaccattag atgctatact gccctagacc 2220 cagaggggcc agaaggccgc cttattctta atatgcattt ttatcaccca atccactcct 2280 gacattagga aaaaacttca aaaattagaa tctggccttc aaacccagca ggaattaatc 2340 aaccttgcct tcaaggtgta caataataga gaggaagcag ccagacggca acgcatttcg 2400 gagttacaat tacttgcctc tgctgtgaga caaaacccag ccacacctcc tgcatacagg 2460 aacttcaaaa tgcctaagac gcagcaatca gacactccta caagacttca tcaggatctt 2520 gcttcaagtg ccagaaatct ggccactggg ccaaggaatg cccacagccc aggattcctc 2580 ccaagccatg tcccatctgt gcaggcaccc actggaaatc agactgccca gctcgcccga 2640 cagccactcc tggagcccct aaagctctag cccaaggctc tctgactcct tcccagatct 2700 attcggctta gcgactgaag attgacgctg cccgatcgcc tcggaagtcc cctggaccat 2760 cacagaagcc gagcttcggg taactctcac agtggagggt aagtccatcc cctgtttaat 2820 cgatacgggg gctacccact ccacgttgcc ttcttttcaa gggcctgttt cccttgcccc 2880 cataactgtt gtgggtattg acggccaagc ttcaaaaccc ctgaaaactc ccccactctg 2940 gtgccaactt ggacaacact cttttatgca ctctttttta gttatcccca cctgcccact 3000 tcccttatta ggccgaaata ttttaaccaa attatctgct tccctgacta ttcctggagt 3060 acagctacat ctcattgctg cccttcttcc caatccaaag cctcctttgt gtcctctaac 3120 atccccacaa tatcacccct taccacaaga cctcccttca gcttaatctc tcccactcta 3180 ggttcccacg ccgcccctaa tcccacttga agcagccctg agaaacatcg cccattctct 3240 ctccatacca ccccccaaaa attttcgccg ctccaacact tcaacactat tttgttttat 3300 ttgtcttatt aatatcagaa ggcaggaatg tcaggcctct gagcccaggc caggccatcg 3360 catcccctgt gacttgcacg tatacatcca gatggcctga agtaactgaa gatccacaaa 3420 agaagtaaaa acagccttaa ctgatgacat tccaccattg tgatttgttc ctgccccacc 3480 ctaactgatc aatgtacttt gtaatctccc ccacccttaa gaaggttctt tgtaattctc 3540 cccacccttg agaatgtact ttgtgagatc cacccctgcc caccagagaa caaccccctt 3600 tgattgtaat tttttattac cttcccaaat cctataaaac agccccaccc ctatcttcct 3660 tcactgactc tcttttcgga ctcagcccac cggcacccag gtgaaataaa cagctttatt 3720 gctcacacaa agcctgtttg gtggtctctt cacacggacg cgtatgaaa 3769 <210> 24 <211> 5644 <212> DNA <213> Homo sapiens <400> 24 gtcaggcctc tgagcccaag ccaagccatc acatcccctg tgacttgcac gtatacaccc 60 agatggcctg aagtaactgg agaatcacaa aagaagtgaa aaggccctgc cccgccttaa 120 ctgatgacat tccaccattg tgatttgttc ctgccccacc ttaactgagt gattaaccct 180 gtgaatttcc ttgtcctggc tcagaggctc ccccactgag caccttgtga ccactgcccc 240 tgcccaccag agaacaaccc cctttggctg taattttcca ttacctttcc aaatcctata 300 aaacggcccc acccctatct cccttcgctg actctctttt tggactcagc ccacctgcac 360 ccaggtgaaa taaacagcca tgttgctcac acaaagcctg tttggtggtc tcttcacatg 420 gacgcacatg aaatttggtg ccgtgactca gatcagggga cctcccttgg gagataaatc 480 ccctgtcctc ctgctctttg ctctgtgaga aagatccacc tacgacctca ggtcctcaga 540 ccgaccagcc caagaaacat ctcaccaatt tcaaatctgg taagtggcct ctttttactc 600 tcttctccag cttccctcac tatccctcaa cctctttctc ctttcaatct tggcgccaca 660 cttcaatctc tcccttctct taatttcaat tcctttcatt ttctggtaga gagagacaaa 720 agagacacgt tttatccatg gacccaaaac tccggtgctg gtcacggact gggaaggcag 780 ccttcccttg gtgtttaatc attgcagaga tgcctgatta ttcacccacg tttcaaaggt 840 gtcagaccac gcagggacgc ctgccttggt ccttcaccct tagcagcaag tcccgctttt 900 ctggggaaga ggcaagtacc ccaatccctt ctctccttgt ctctacccct tctctgcttt 960 tctgggggag ggacaagtac ccctcaactg cttctccttc acccttagcg gcaagtcccg 1020 cttttctagg gggcaagaac ccccaatccc ttatttccac accccaacct cttatctctg 1080 tgccccaatt ccttatttcc atgccccaac cctttctctg cttttctgga gggcaagaaa 1140 cccccacccc ttctccgtgt ctctactctt ttctctggac ttgcctcctt cactatgggc 1200 aagcttccac cttccattcc tccttcttct cccttagcct atattcttaa gaacttaaaa 1260 cctcttcaac tctcacctga cctaaaatct gagcatctta ttttcttctg caatgcgctt 1320 gaccccaata caaactcgac agtagttcca aatagccgga aaatggcact ttgaattttt 1380 ccatcctaca agatctaaat aatccttgtc ataaaatggg caaatggtct gaggtgcctg 1440 acgtccaggc attcttttac acatcagtcc cttcctagtc tctgtgccca gtgcaactcg 1500 tcccaaatct tccttctttc ccccctccgc ctgtcccctc agtcccaacc ccaagcgttg 1560 ctgagtcttt ctaatcttcc ttttctacag acccatctga cccctcccct cctcgccagg 1620 ccaagctagg tcccaattct tcctcagcct ccgctcctct accctgtaat ctttttatcg 1680 cctcccctcc tcacacctgg tccggcttac agtttctttc tgtgactagc cctcccccac 1740 ctgcccagca atttactctt aaaaaggtgg ctggagccaa aggcatagtc aaggttaatg 1800 ctcctttttc tttatcccaa atcagaagcg tttaggctct tttttatcaa atataaaaac 1860 ccagcccagt tcatggctcg ttcggcagca atcctgagac gttttacagc cctagaccct 1920 aaaaggtcaa aaggccatct tattctcaat atacatttta ttacccaatc tgctcctgac 1980 attaaataaa actccaaaaa ttagaatctg gccctcaaac cccacaacag gacttaatta 2040 acctcacctt caaggtgtac aataataaaa aaaaaaattg caattccttg cctccactgt 2100 gagacaaacc ccagccacat ctccagcaca caagaacttc caaacgcctg aaccgcagcg 2160 gccaggcgtt cctccagaac ctcctccccc aggagcttgc tacaagtgcc agaaatctga 2220 ccaccaggcc aaggaatgcc tgcagcccag gattcctcct aagccatgtc ccatctgtgc 2280 gggaccacac tggaaatcgg actgttcaac tcacctggca gccactccca gagcccctgg 2340 aactctggcc caaggctctc tgactgactc cttcttggct tagcggctga agattgatgc 2400 tgcctcattg cctcagaagc cccatagacc atcacggacg ccaagcttcc ggtaactctc 2460 acagtggagg gtaagtccgt ccccttctta atcaatacag aggctaccca ctccacatta 2520 ccttcttttc aagggcctgt ttcccttgcc tccataactg ttgtgggtat tgacgccagg 2580 cttctaaacc tcttaaaact ccccaactct ggtgctaact tagacaatac tcttttatgc 2640 actctttttt agttatcccc acctgcccag ttcccttatt aggccgagat attttaacca 2700 aattatctgc ttccctgact attcctggat atagccacat ctcattgctg cccttcttct 2760 caatccaaaa gcctcctttg cttcctcctc ttgtattccc ccaccttaac ccacaagtat 2820 aagatacctc tactccctcc ttggcgaccg atcacccacc ccttaccatc tcattaaaac 2880 ctaatcaccc ttaccccact caatgccaat atcccatccc acagcaagct ttaaaaggat 2940 taaaacctgt tatcacttgc ctgctacagc atgggcttct aaaacctata aactctcctt 3000 accattcccc cattttacct gtcctaaaac cagacaagcc ttacaagtta gttcagaatc 3060 tgcgccttat caaacaaatt gttttgccta tccactctat ggtgccaaac ccatatactc 3120 tcctatcctc aatacctccc tctactaccc attattctgt tctggatctc aaacatgctt 3180 tctttactat tcctttgcac ccttcatccc agcctctctt tgtcttcact tagactgacc 3240 ctgacaccca ttaggctcag caaattaccc gggctgtact gccgcaaggc ttcacagaca 3300 gcccccaata cttcagtcaa gcctaaattt catcctcatc tgttacctat ctcggcataa 3360 ttctcataaa aacacacgtg ctctccctgc tgatcatgtc cgattaatct cccaaacctc 3420 aatcccttac taaagaacaa ctcctttcct tcctaggcat ggttagtgcg gtcagaattc 3480 ttacacaaga gccaggacca catcgtgtag cctttctgtc caaacaactt gaccttactg 3540 ttttagccta gccctcatgt ctgcgtgcag cggctgccgc tgctttaata cagttagagg 3600 ccctaaaaat cacaaactat gttcaactca ctctctacat ttctcataac ttccaaaatc 3660 tattttcttc ctcatacctg acgcatatac tttctgctcc ccggctcctt cagctgtact 3720 cactctttaa gtcccacaat taccattgtt cctgccccgg acttcaatct ggcctcccac 3780 attattcctg atgccacacc tgacccccat gactatctct ctgatccacc tgatattcac 3840 cccatttccc catatttcct tctttcttgt tcctcaccct gatcatgctt gatttattga 3900 tggcagttcc accaggccta atcgccacac accagcaaag gcaggctatg ctatagtaca 3960 agccactagc ccgcctctca gaacctctca tttcctttcc atcgtggaaa tctatcctca 4020 aggaagtaac ttctcagtgt tccatctgct attctactac tcctcaggca ttattcaggc 4080 cccctccctt ccctacacat caagctcgag gatttgcccc cacccaggac tggcaaatta 4140 gctttactca acatgtcctg agtcaggaaa ctaaaatacc tcttagtcta aatagacact 4200 ttcactgaat aagtaaaggc ctttcctaca gggtctgaga aggtcaccac agtcatttct 4260 tcccttctgt cagacataat tcctcagttt agccttccta cctctataca gtctgataac 4320 agaccagcct ttattagtca aatcagccaa gcagtttttc aagctcttag tattcagtga 4380 aacctttata tcctttacgg tcctccgtct tcaagaaaag tagaacggac taaaggtctt 4440 ttaaaaacac acctcaccaa gctcagccac caacttaaaa aggactggac aatactttta 4500 tcactttcac ttcccagaat tcaggcctgt cctcagaatg ctacaaggta cagcccattt 4560 aagctcctgt atagacagac gctccttttt attaggcccc agtctcattt gacaccagac 4620 caacttagac tgtgccccaa aaaaacttgt catccctact atcttttgtc tagtcatact 4680 cctattcacc attctgaact acatgccctg ctcttgttta cactgccggt ttacactgtt 4740 tctccaagcc atcacagctg atatctcctg gtgctatccc caaactgcca ctctaaactc 4800 ttgaagtaaa taaataatct ttgctggcag gactatgctg aatctcctta ggcactctct 4860 aatcagatgt cctaggtcct cccaattctt agacctttta tacctgtttt tctccttctc 4920 ttattccatt tagtttttta attcatacaa aaccgtatcc aggccatcac caatcattct 4980 atacgacaaa tgttccttct aacaacccca caatatcacc ccttaccaca agatcttcct 5040 tcagcttaat ctctcccact ctatgttccc acactgcccc taatcccgct tgaagcagcc 5100 ctgagaaaaa tcgcccattc tctctccata ccacccccaa aaattttcgc cgccccaaca 5160 cttcaacact attttgttta atttttctta ttaatataag aaggcaggaa tgtcaggcct 5220 ctgagcccaa gccaagccat cacatcccct gtgacttgca cgtatacacc cagatggcct 5280 gaagtaactg gagaatcaca aaagaagtga aaaggccctg ccccgcctta actgatgaca 5340 ttccaccatt gtgatttgtt cctgccccac cttaactgag tgattaaccc tgtgaatttc 5400 cttgtcctgg ctcagagtct cccccactga gcaccttgtg acccccgccc ctgcccacca 5460 gagaacaacc ccctttgact gtaattttcc atttcctttc caaatcctat aaaacggccc 5520 cacccctatc tcccttcgct gactctcttt ttggactcag cccacctgca cccaggtgaa 5580 ataaacagcc atgttgctca cacaaagcct gtttggtggt ctcttcacat ggacgtgcat 5640 gaaa 5644 <210> 25 <211> 5687 <212> DNA <213> Homo sapiens <400> 25 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac atatacattc 60 agatggcctg aagcaactga agattcacaa aagaagtgaa aatagcctta actgatgaca 120 ttccaccatt gtgatttgtt tctgccccac cctaactgat caatgtactt tgtgatctcc 180 cccaccctta agaaggttct ttgtaattct ccccaccctt gagaatgtac tttgtgagat 240 ccaccccctg cccgcaaaac attgctccta actccaccgc ctaccccaaa acctataaga 300 actaatgata atcccaccac cctttgctga ctctcttttc ggacttagcc cgcctgcacc 360 caggtgaaat aaacagcctt gttgctcaca caaagcctat ttggtggtct cctcacatgg 420 acgtgcatga cattgggtgc tgaaacccgg gacaggagga ctccttcggg agaccagtcc 480 ccttcccctg tcctcgccct cactccttga ggagatccac ctgcaacctc gggtcctcag 540 accaaccagc ccaaggaaca tctcatgaat ttcaaattgg gtaagcggtc ttttcactct 600 cttctccagc ctctcttgct acccttcaat ctccctctct cgctaccctt caatctccca 660 gtccttccaa ctccagttct ttttcctctc tagtagagac aaaggaaaca cattttatct 720 gtagactcca gcgccagtca cggacttggg aagacagtct tcccttggtg tttaatcact 780 gcggggacgc ctgcctgatt attcactcac actccattgg tgtctgatca ccgcggggac 840 gcctgccttg gtcattcacc cacattcctt tggtggcaag tcaattgcgg ggacacctgc 900 tttggctgct cacctactcc cttctccatg tctctacctt tctctttaaa cttacctcca 960 ttactatggg caaccttcca ccctccattc ccccatcttc tcccttagcc tgtgttctca 1020 aaaacttaaa acctcttcaa ctctcgcctg acctaaaacc taagcgtctt attttcttct 1080 gcaacaccgc ttggccccaa tacaaactca ataatggttc taaatagcta gaaaatgaca 1140 cttttgattt ctccatttta caagacctgg atgatttttg ttgaaaaatg ggcaaatggg 1200 tctgatgtgc ctgacatcca ggcattgttt catacactgg tccctcctta gtctctgctc 1260 ccaatgcgac tcatcccaaa tctttcttct ttctctgcgg tctgttcctt cagtctccac 1320 cccaagctct gagtcctttg aatgctcctt ttctacagac ccatctaacc tctcccctcc 1380 tacccaggct gctcctcacc aggctgagcc aggtcccaat tcttcctcag cctccgctcc 1440 ccgatcctat aatcctttta tcacctcccc tcctcacacc cggtccagtt tacagttaca 1500 ttcctccact agccctcccc cacctgccca acaatttcct cttaaagagg tggctggagc 1560 tgaaggcata gccaaggtaa atgctccttt ttccgacctc tcccaaatca gggtttaggc 1620 tctttttcat caaatataaa aactcaaccc agttcatggc ccgtttggca acaaccctta 1680 gacggtttac tgccctagac ccagaagggc cagaaggccg tcttattctc aatatgcatt 1740 ttattaccca atccactggc gacattagaa aaagctccaa aaattagatt ctggccctca 1800 aaccccacaa cgggacctaa ttaacctcac cttcaaggtg tacaataata gagtagaggc 1860 agccaagtag caacgtattt ctgagttgca attctttgcc tccaccgtga gacaaacccc 1920 agccacatct ccagcacaca agaactccaa atgcctaaac tgcggcggcc aggcattcct 1980 ccaggactgc ctgccccagg atcttgcttc aagtgccaga aatctggcca ccgggccaag 2040 gaatgcctgc agcctgggat tcctcctatg ccatgtccca tctgtgcggg accccactgg 2100 aaattggact gtccaactta cccggcagcc actcccagag cccctggaac tctggcccaa 2160 ggctctctga ctgattcctt cccagatctt cttgacttag cagctgaaga ctgatgctgc 2220 ccgattgcct tggaagcccc cctagaccat cacagatgcc gagcttcggg aactctcaca 2280 gtggagggta agtccgaccc cttcttagtc aatatggagg ctactcactc cacattacct 2340 tcttttcaag ggcctatttc ctttgcctcc ataactgttg tgggtattga tggccaggct 2400 tctagacccc ttaaaactcc ccaactctga tgccaacttg gacaacattc ttttatgcgc 2460 tcctttttag ttatccccac ctgcccagct cccttattag gctgagacat tttaactaaa 2520 ttatctgctt ccctgactat tcctagccta tagcctcacc tcatttacac ccttttcccc 2580 agttcaacac ctccttcgcc tcctcccctt gtacctcccc accttaatcc acaagtatag 2640 ggcacctcta ctccctcctt ggcgtccaat tatgcacctc ttaccatccc attaaaacct 2700 aatcaccctt accccactca atgccaatat cccatcccac agcatgcttt aaaaggatta 2760 aagcctgtta tcacttgcct gttacagcac ggccttttac agcctataaa ctctccttac 2820 aattcctcca ttttacttgt ccaaaaacca gacaagcctt acaggttagt tcaggatttg 2880 tgccttatca accaaattgt cttgcctatc caacctgtga tgccaaagcc atatactctc 2940 ctatcctcaa tacctccctc cacaacccat tattctgttc tggatctcaa acatgttgtc 3000 tttactattt ctttgcaccc ttcatcccag cctctcttca cttttacttg aactgaccct 3060 gacacccatt aggctaagca aattacctgg gctatactgc cacaaggctt cacagacagc 3120 tcccattact tcagtcaagc cgaaatttct tcctcatccg ttacctatct cggcataatt 3180 cttcatgaaa acacacgtgc tctccctgct gattgtgtct ggctaatctc ccaaacccaa 3240 ccccttctac aaaacaacaa ctcctttcct tcctatgcat ggttaggtac ttccgccttt 3300 ggatacctag ttttaccatc ctgactaaac cattatataa actcacaaaa gcaaacctag 3360 ctgaatccat agatcctaaa tcctttcccc actcctcttt ccattcctta aaaacagccc 3420 tagaagctgc tcccacacta gctctcccta actcatcccg acccttttca ttacacacag 3480 ccaaactaca gggctgtgca gtcaaaattc ttacacaaga gctgggacca caccctgtag 3540 cctttccatc caaacaactt gaccttacct ttttaggcta gcctctacat tattcctgat 3600 accacacctg acccccatgg ctgtatctct ctaatccacc tgacattcac tccacttccc 3660 catatttcct tctttcctgg tcctcaccct gatcacactt ggtttattga tggcagttcc 3720 accaggccta attgccactc accagcaaaa gcaggctatg ctatagtatc ttccacatct 3780 atcattgagg ctactgctct gcctccctcc actacctctc agcaagccga actcattgcc 3840 ttaactcgag ccctcactct tgcaaaggaa ttacgtgtca atatttatac tgactccaaa 3900 tatgccttcc atatcctgca ccaccatgct gttatatggg ctgaaagagg tttccttact 3960 acgcaagggt cctccatcat taatgcctct ttaatgaaaa ctcttctcaa ggctgcctta 4020 cttccaaaga aagctggagt catacactgt aagggccacc aaaaggcatc agatcccatt 4080 gctaggggca gcacttatgc tgataaggta gctaaagaag cagttagcat tccaacttct 4140 atccctcacg gcagtttttc tccttctcat ctggtcactc ccacctactc tcccactgaa 4200 acttccacct atcaatctct tcccacacaa gcaaatgctt cttggaccaa ggaaaatatc 4260 tccttcttgc ctcacaggcc cattctattc tatcgtcatt tcataacctc ttccatgtag 4320 gttacaagcc gctagcccac ctcttagaac ctctcatttc ctttccattg tggaaatcta 4380 tccttaagga aatcacttct cagtgttcca tctgctattc tactacccct cagggattgt 4440 tcaggccccc tcccttccct acacatcaag ctcggggatt tgccaccccc aggactggca 4500 aattgacttt attcacatgc ccaagtcagg aaactaaaat acctcttgat ctgggtagac 4560 acttttgctg gatgtgtaga ggcctttccc actgggtctg agaaggccac catggtcatt 4620 tcttcccttt tgtcagacat aattcctcag tttggctttc tcacctctat acagtccaat 4680 aacagaccag cctttactag tcaaataccc aagcaatttc tcaggctctt ggtattcagt 4740 ggaactttca tacccctgac cgtcctcaat cttcaggaaa gataaaacag actaatggtc 4800 ttttcccaaa aactcaccaa ccaagtaagt aattacactg gacccccttg ggcactctct 4860 aattggatgt cctgggtcct cccaattctt agtcctttaa tacctatttt tctccttctt 4920 ttattcagac cttatatctt ctgtttaatt tctcaattca tccaaaactg tatccaggcc 4980 atcgccaatc attctatatg aaaaatgctc cttctaatca cccacaatat cacccctgac 5040 cacaaaatct tccttcaact taatctctcc cactctaggt tcccacacca cccctaatcc 5100 cgctcgaagc agccctgaga aacatcgccc attatctctc cataccaccc ccaaaatttt 5160 tcacctctcc aacacttaac cactattttg ttttgctttt cttattaaca taagaagaca 5220 ggaatgtcag gcctctgagc ccaagctaag ccatcatatc ccctgtgacc tgcacgtata 5280 catccagatg gcctgaagca actgaagatc cacaaaagaa atgaaaatag ccttaactga 5340 tgacattcca ccattgtgat ttgtttctgc cccaccctaa ctgatcaatg tactttgtaa 5400 tctccccaac ccttaagaag gttctttgta atctccccca catcttaaga aggttctttg 5460 taattctccc cacccttgag aatgcacttt gtgagatcca ctccctgccc acaaaacatt 5520 gctcctaact ccaccgccta ccccaaaacc tataagaact aatgataatc ccaccaccct 5580 ttgctgactc tcttttcgga ctcagcccac ctgcacccgg gtgaaataaa cagccttgtt 5640 gctcacacaa agcctgtttg gtggtctctt cacacagacg tgcatga 5687 <210> 26 <211> 5873 <212> DNA <213> Homo sapiens <400> 26 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcat gtatatgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aaggccctgc cccgccttat 120 ctgatgacat tccaccattg tgatttgttc ttgccccacc ttaactgagt gattaaccct 180 gtgaatttcc ttttcctggc tcagaagctc ccccactgag caccttgtga cccccgcccc 240 tgcccaccag agaacaaccc cctttgactg taattttcca ttaccttccc aaatcctaca 300 aaacggcccc acccctatct ccctttgctg actctctttt cggactcagc ccacctgcac 360 ccaggtgaaa taaacaacca tgttgctcac acaaagcctg tttggtggtc tcttcacatg 420 gacgcgcatg aaatttggtg ccatgactcg gatcggggga cctcccttgg gagatcaatc 480 ccctgtcctc ctgttctttg ctccgtgaga aagatccacc tacaacctca ggtcctcaga 540 ccgaccagcc caaggaacat ctcaccaatt ttaaatcagg taagcggtct cttcttactc 600 tcttctccaa cctctctcac tgtccctcaa ccactttctc ctttccactc ttcaatctct 660 cccttctctt aatttcaatt cctttcattt tctgggagag acaaaggaga catgttttat 720 ccgtggaccc aaaactccgg cgccggtcac agactgggaa ggcagctttc ccttggtgtt 780 taatcattgc agggacgcct ctctgattat tcacccacgt ttcaaaggtg tcagaccacg 840 cagggacgcc tgtcttggtc cttcaccctt agcggcaagt cccgcttttc tggggaaggg 900 gcaagtaccc caaccccttc tctccttgtc tctacccctt ctctgctttt ctggggaagg 960 ggcaagtacc ccaacccttc tctccttgtc tctacccctt ctctgctttt ccgggggtgg 1020 ggcaagtacc ccaacccctt ctctccttct ctccacccct tctctgcttt cctggggcag 1080 gggcaagtac cactcaaccc cttctccttc acccttagcg gtaagtcccg ctttcctagg 1140 gggcaagaac cccccaatcg cttatttcca tgccccaacc tcttatctct gcgccccaat 1200 cgcttatttc catgccccaa cctcttatct ctgtgcccca attgcttatt tccgcgcccc 1260 aacctgttat ctctgtgccc caatccctta cttccatgcc ccaacctctt atgtctgcac 1320 cccaatccct tatttccatg ctccgaccct ttctctgctt ttctggtggg caagaaaccc 1380 ccaccccttc tccatgtctc tactcttttc tctgggcttg cctccttcac tatgggcaag 1440 cttccacctt ccattcctcc ttcttcttcc ttagcctgta ttcttaagaa cttaaaacct 1500 cttcaattct cacctgacct aaaatctaag catctcattt tcttctgcaa tgccgcttga 1560 ccccaataca aactggacag tagttccaaa tagccagaaa acggcacttt caatttttcc 1620 atcctataag atctaaataa ttcttgtcgt aaaatgggca aatggtctga ggtgcctgac 1680 gtccaggcat tcttttacac atcagtccct tcctagtctc tgtgcccagt gcaactcgtc 1740 ccaaatctcc cgcctgtccc ctcagtccca accccaagcg tcgctgagtc tttctaatct 1800 tccttttcta cagacccatc tgacctctcc cctccttgcc aggccaagct aggtcccaat 1860 tcttcctcag cctccgctcc tccaccctgt aatcttttta ttgcctcccc tcctcacacc 1920 tggtccggct tacagtttcg ttccgtgact agcccttccc cacctgccta gcaatttact 1980 cttaaaaagg tggctggagc taaaggcata gtcaaggtta atgctccttt ttctttatcc 2040 caaatcagat agcgtttagg ctctttttca tcaagtataa aaatccagcc cagttcatgg 2100 ctcgtttgac agcaaccctg agacgcttta tagccctaga ccctaaaagg tcaaaaggcc 2160 atcttattct caatatacat tttattaccc aatctgctcc cgacattaaa taaaactcca 2220 gaaattggaa tctggccctc aaaccccaca acaggactta attaacctca ccttcaaggt 2280 gtgcaataac agaaaaaagt tgcaattcct tgcctccact gtgagacaaa ccccagccac 2340 atctccagca cacaagaact tccaaacgcc tgaaccatag caaccaggcg ttcctccaga 2400 acctcctccc ccaggcgctt gctacacgtg ccggaaatct ggccactggg ccaaggaatg 2460 cccgcagcct gggattcctc ctaagccgcg tcccatctgt gtgggacccc actgaaaatc 2520 ggactgttca actcacctgg cagccactcc cagagcccaa ggaactctgg gcccaaggct 2580 ctctgactga ctccttcttg gcttaccggc tgaagactga cgctgcctga tcacctcaga 2640 agccccgtag accatcacgg acgccgagct ttaggtaact ctcacggtgg agggtaagtc 2700 catccccttc ttaatcaata cggaggctac ccactccaca ttaccttctt ttcaagggcc 2760 tgtttccctt gcctccataa ctgttgtggg tattgacagc caggcttcta aacctcttaa 2820 aactccccaa ctctggcgcc aacttagaca ctactctttt aagcactcct ttttagttat 2880 ccccacctgc ccagttccct tattaggctg aggcacttta agtaaattat ctgcttccct 2940 gactattcct ggactacagc tatatctcat tgccgccctt cttcccaatc caaagcctcc 3000 tttgcgtcct cctcttgtat ccccccacct taacccacaa gtataagaca cctctactcc 3060 ctccttggcg actgatcatg caccccttac catctcatta aaacctaatc acccttaccc 3120 cactcaacgc caatatccca tcccacagca cgctttaaaa ggattaaagc ctgttatcac 3180 tcgcctgcta cagcatggcc ttttaaagcc tataaactct ccttacaatt cccccatttt 3240 acctgtccta aaaccagaca agacttacaa gttagttcag gatctgtgcc ttatcaacca 3300 aattgttttg cctatccccc ttgtggtgcc caacccgaac actcttttgt cctcaatacc 3360 ttcctccaca actcactatt ccgtgcttga tcgtaaagat gcttttttca ctgttcccct 3420 gcacccctcg tccccgcctc tctttgcttt cacttagact gaccctgaca cccatcaggc 3480 tcagcaaatt acctgggctg tcctgccgca aggcttcaca gacagccccc attacctcag 3540 tcaagcccaa atttcatcct catctgttac ctatctcggt ataattctca caaaaacaca 3600 cgtgctttcc ctgctgatca tgtctgatta atctcccaaa cctcaatccc ttacaaaaca 3660 acaactcctt tccttcctag gcatggttag tgtggtcaga attcttacac aagagccagg 3720 accgcaccct gtagcctttc tgtccaaaca acttgacctt actgttttag cctagccctc 3780 atgtctgtgt gcagcggctg ccgctgcttt aatactttta gaggccctga aaatcacaaa 3840 ctatgctcaa ctcactctct acatttctca acttccaaaa tctattttct tcctcatacc 3900 tgacgcatac actttctgct ccccggctcc ttcagctgta ctcactcttt gttaagtccc 3960 acaattacca ctgttcctgg cccggacttc aatctggcct cccacattat tcctgatacc 4020 acacctgacc cccatgactg tatctctctg atccacctgc tattcacccc atttccctgt 4080 atttccttct ttcctattcc tcaccctgat cacgcttgat ttattgatgg cagttccacc 4140 aggcctaatc gccacatacc agcaaatgca ggctatgcta tagtacaagc cactagcctg 4200 cctctcagaa cctctcattt cctttccatc gtggaaatct atcctcaaga aaataacttc 4260 tcagtgttcc atctgctatt ctactactcc tcagggatta ttcaggcccc ctcccttccc 4320 tacacatcaa gctcgagaat ttgcccccac ccaggactgg caaattagct ttactcaaca 4380 tgcccgagtc aggaaactaa aatacctctt agtctaaata gacactttca ctgaataagt 4440 aaaggccttt cctacagggt ctgagaaggc caccacagtc atttcttccc ttctgtcaga 4500 cataattcct cagtttagcc ttcccacctc tatacagtct gatagcagac cagcctttat 4560 tagtcaaatc agccaattag tttttcaggc tcttagtatt cagtgaaacc tttatatccc 4620 ttacggtcct ccgtcttcaa gaaaagtaga acggactaaa ggtcttttaa aaacacacct 4680 caccaagctc agccaccaac ttaaaaagga ctggacaata cttttaccac tttcacttct 4740 cagaattcag gcctgtcctc agaatgctac aaggtacagc ccatttaagc tcctgtatag 4800 atgctccttt ttattaggcc ccagtctcat tccagacact ggaccaactt agactgtgcc 4860 cccaagaaaa cttgtcatcc ctactatttt ctgtctagtc atattcctat tctccattct 4920 caactactca cacatgccct gctcttgttc acactgccag tttacactgt ttctccaagc 4980 catcacagct gatatctcct cgtgctatcc ccaaactgcc actcttaact cttgaagtaa 5040 ataaataatc tttgctggca ggactatgct gaatctcctt aggcactctc taatcagatg 5100 tcctaggtcc tcccaattct tagacctttt atacctgttt ttctccttct tattccattt 5160 agtttttcaa ttcacacaaa actgtatcca ggccatcacc aatcatacta tatgacaaat 5220 gtttcttcta acaaccccac aatatcaccc cttaccacaa gatctccttt cagcttaatc 5280 tctcccactc taggttccca cccgccccta atcccgcttg aagcagccct gagaaacatc 5340 gcccattctc tctccatacc accccccaaa aattttcgcc accccaacac ttcaacacta 5400 ttttgtttta tttttcttat taatataaga aggcaggaat gtcagtcctc tgagcccaag 5460 ccaagccatc gcatcccctg tgacttgcac gtatacgccc agatggcctg aagttactga 5520 agaatcacaa aagaagtgaa aaggccctgc cccgccttaa ctgatgacat tccaccattg 5580 tgatttgttc ctgccccacc ttaactgagt gattaaccct gtgaatttcc ttctcctggc 5640 tcagaagctc ccccactgag caccttgtga cccccgcccc tgcccaccag agaacaaccc 5700 cctttgactg taattttcca ttaccttccc aaatcctata aaatggcccc atccctatct 5760 ccctttgctg actctctttt cggactcagc ccacctgcac ccaggtgaaa taaacaacca 5820 tgttgctcac acaaagcctg tttggtggtc tcttcacacg gacacgtatg aaa 5873 <210> 27 <211> 7457 <212> DNA <213> Homo sapiens <400> 27 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac gtacacatcc 60 agatggccag ttcctgcctc aactgatgac attccaccac aaaacaggtg aaaatggcct 120 gttcctgcct taactgatga cattatcttg tgaaattcct tctcctggct catcctggct 180 caaaagctcc cctactgagc tccttgtgac cccactcctg cctgccagag aacaatcccc 240 ctttttcctt tacctaccca aatcctataa aacggcccca cccgtatctc ccttcaatga 300 ttctcttttc ggactcagcc tgcctgcacc caggtgaaat aaacagcctt gctgctcaca 360 caaagccttt ttggtggtct cttcacaccg aagcgcatga aagttggtgc tgtgactcgg 420 atagggggac ctcccttggg agatcaatcc cctgtcctcc tgctctttgc tccatgaaaa 480 agatccacct acgacctcgg gtcctcagac ccaccagccc aaggaacatc tcaccaattt 540 taaatcgggt aagcggcctc ttcttactct cttctccaac ctctctcact atccctcaac 600 cactttctcc tttcaatctt gatgctaccc ttcaatctct cctttctctt aatttccttt 660 cattttctag tagagacaaa ggagacacgt tttatccgtg gacccaaaac tctggcgcca 720 gtcacggact caggaaggca gccttccctt ggtgtttaat cattgcaggg acgcctctga 780 ttattcacct atgtttcaga gatgtctgac cacccaagga cgcctgcctt ggtccttcac 840 ccttagtggc aagtactgct tttctggggg gcaagaaccc cccaacccct tctctccatg 900 tctctacccc ttttccactt ttctggaggg caagaacctc caaccccttc tccttcaccc 960 ttagtggcaa gtaccgcttt tctagggggc aaaaaccccc caaccccttc tctccatgtc 1020 tctacccctt ctctgatttt ctgggggcaa gaacccctgg atccataatt tccacgcccc 1080 gacctcttat ctctgcaccc cgatccctta tttctacgcc tcgacctctt atctctgtgc 1140 ccaacccctt tcctgctttt ctggagggta agaacccccg aaccccttcc ctccgtgtct 1200 ctactctctc ttttctctgg gcttgcctcc ttcgctatgg gcaaccttcc accctccatt 1260 cctcctcctt ctcccttagc ctgtgttctt aagaacttaa aacctcttca actcacacct 1320 gacctaaaac ctaaatgccg aattttcttc tgcaatgccg cttgacccca atacaaactc 1380 gacagtggtt ccaaatagcc agaaaatggc actttcaatt tttccatcct acgagatcta 1440 aataattctt gtcataaaat aggcaaacgg tctgagatgc ctgacgtcca ggcattcttt 1500 tacacatcgg tccctcccta gtctctgttc ccaatgcaac ttatcccaaa tcttccttct 1560 ttccctccca cctgtcccct cagtcccaac cccaagcatc gctgagtctt tctaatcttc 1620 cttttctaca gacccatctg acttctcccc tcctcgccag gccgagctaa gtcccaattc 1680 ttcctcagcc tctgctcctc caccctacaa tccttttatc acctcccctc ctgaaacctg 1740 gtccggctta cagtttcctt ccgtgactat ccctccccca cctgcccagc aatttcctct 1800 taaaaaggtg gctggagcta gaggcatagt caaggttaat gctccttttt ctttatccca 1860 aatcagatag cgtttaggct ctttttcatc aaatataaaa acccagccca gttcatggat 1920 cgtttggcag caaccctgag atgctttaca gccctaggcc ctaaaaggtc aaaaggccgt 1980 cttattctta atatatattt tattacccaa tctgctcccg acattaaata aaactccaaa 2040 aattaaattc cggccctcaa atcccacaac aggacttaat taacctcacc ttcaaggtgt 2100 acaataatag agtagaggca gccaagtagc aatgtatttc tgagttgcaa ttccttacct 2160 ccactgtgag acaaacccca gccacatctc cagcacacaa gaactccaaa tgcccaaacc 2220 gcagctgcaa ggggttcctc cagaacctcc accctcaaga gcttgctata agtgtgagaa 2280 atctggccaa ttggccaagg aatgcccaca gcccgggatt cctcctaagc cgcgtcccat 2340 ctgtgcagga acccactgaa aatcagactg ttcaactcac ctggcagccg ctcccagaac 2400 ccctggaact ctggcccaag gctctctgac tgactccttc ccagatcttc tcagcttagc 2460 agctgaagac tgacactgcc cgattgcctc ggaagcctac aggaccatca cagacgctct 2520 aggtaactct cacagtggaa ggtaagtctg tccccttcta aatcaatacc gaggctaccc 2580 actccatatt accttctttt caagggcctg tttcccttgc ctccataact gttgtgggta 2640 ttgacggcca ggcttctaaa cctcttaaaa actccccaac tctggtgcca acttagaaga 2700 cactcttttt gcactctttt ttaattatcc ccacctgccc agttccctta ttaggccgag 2760 acactttaac taaattatct gcttccctga ctactcctgg gctacagcca cacctcattg 2820 ccaccttttc ccccagttca aagcctcctt cacatcctcc ccttgtatct ccccacctta 2880 acccacaagt atatgaccct ctactccctc cttagcgacc atcatgcacc ccttaccatc 2940 ccattaaaac ctaatcaccc ttaccctgct caatgccaat atcccatccc acagcatgct 3000 ttaaaaggat taaagcctgt taccactcgt gtgctacagc atggcctttt aaagcctgta 3060 aactcccctt acaattccat ttcacctgtc ctaaaaccag acaagcctta caggttagtt 3120 caggatctgc gccttatcaa ccaaactgtt ttgcctatcc accccgtggt gccaaacgca 3180 tatactctcc tatcctcaat acctctctct acaacccatt attctgttct ggatttcaga 3240 catgctttct ttactattcc tttgcaccct tcatcccagc ctctcttcgc tttcacttgg 3300 actgaccctg acacccatta ggctcagcag attacctgag ctgtactgcc gcaaggcttc 3360 acagacagcc ccctttactt cagtcaagcc caaatttctt cctcatcagt ttcctatctc 3420 agcataattc tcataaaaac acacatgctc tccctgctga tcatgtccga gtaatctccc 3480 aaacctcaat cccttataaa acaacaactc ctttccttcc taggcatggt tagcgcagtc 3540 agaattcttt cacaagagcc gggaccgcac cctgtagcct ttctgtccaa acaactttga 3600 ccttactgtt ttagcctagc cctcatgtct gtgtgcagtg gctgccgctg ctttaataat 3660 tttagaggcc ctaaaaatca caaactgtgc tcaactcact ctacatttct cataacttcc 3720 aaaatctctt ctcttcctca tacctgacac gtatactttc tgctccccgg ctccttcagc 3780 tgtactcact ctttgttgag tctcccacaa ttaccattgt tcctggcacg gacttcaatc 3840 tggtctccca cattattctg gataccacac ctgaccctca tgattgtatc tctctgatcc 3900 acctgacatt cacctcattt ccccatattt ccttctttcc tttttctcac cctgatcaca 3960 tttagtttat tggtggcagt tccaccaggc ctaatcgcca ctcaccagca aaggcaggct 4020 atgctatagt atcttccaca tctatcattg aggctaccgc tttgcccccc tccactacct 4080 ctcagcaagc caaattagtt gccttaactc aagtcctcac tcttgaaaaa ggactacgcg 4140 tcaatattta cactgactct aaatatgcct ttcatattct gcaccatcat gctgttatat 4200 aggctgaagg aggtttcctc actacgcaag ggtcctccat cattaatgcc tctttaataa 4260 aaactctgct caaggcggct ttacttccaa aggaagctgc agtcattcac tgcaaaggcc 4320 atcaaaaggc gtcagatccc attgctctag gcaacgatta tgctgataag gtggctagac 4380 aagcagctag atttccaact tctgtccttc acggccagtt ttcctccttc gtatcagtca 4440 ctcccaccta ctcccccgct gaaacttcca cctatcaatc tcttttccac acaaggcaaa 4500 tggttcttag accaaggaaa atatctcctt ccagcctcac aggcccgttc tattctggtg 4560 tcatttcata acctctcatg taggttacaa gccgctagcc tgtctcttag aacctctcat 4620 ttcctttcca tcctggaaat ctatcctcaa ggaaattact tctcagtgtt ccatctgcta 4680 ttctactacc cctcagggat tgttcaggcc tcctcccttt cctacacatc aagctcaggg 4740 atttgtccct gcccaggact agcaaattga ctttactcac atgccctgag tcggaaaact 4800 aaaatacctc ttagtctagg tagacacttt cactgggtgg gtagaggcct ttcccacagg 4860 gtctgagaag gccatcgctg tcatttcttc ccttctgtca gacataattc ctcggtttgg 4920 ccttcccacc tctatacagt ccgatagcag actggccttt attagtcaaa tcagccaagc 4980 attttttcag gctcttggta ttcagtgaaa cctttatatc ccttacggtc ctcagtcttc 5040 aggaaaggta gaacggacta atagtctttt aaaaacacac ctcaccaagc tcagccacca 5100 acttaaaaag gactggacaa tacttttacc actttgcctt ctcagaattc aggcctgtcc 5160 tcggaatgct acaaggtaca gcccatttga gctcctgtat agacgctcct ttttatttgg 5220 ccccagtctc attccaggca ccaggccaac ttagactgtg ccccaaaaaa cttgtcatcc 5280 ctactatctt ctgtctagtc atacacctat tcaccgtttt caactactca tacatgccct 5340 gctcttgttt acactgccag tttacactgt tcctccaagc catcacagct gatatcccct 5400 ggtgctatcc gcaaactgcc actcttaact cttaaagtaa ataaataatc tttgctggca 5460 ggactatgct gaatctcctt cgcactctct aattaaatgt cctaggtcct cccaattctt 5520 agacctttaa tacctggttt tctccttctc ttattccatt tttcaattca tacaaaaccg 5580 tatccaggcc atcaccaata attctaaatg acaaatgttt cttctaacaa ccccacaata 5640 tcacccctta ccacaaaatc ttccttcagc ttaatctctc ccactctagg ttcccacgcc 5700 acctctaatc ccgctggaag tagccctgag aaacatcgcc cattatctct ccataccacc 5760 cctaaaaatt ttcactgtcc caacacttta ccacaatttc attttatttt tcttattaat 5820 ataagaagtc aggaatgtca ggcctctgag cccaagctaa gccatcatat cccctgtgac 5880 ctgcaggtac acatccagat ggccagttcc tgccttaact gatgacattc caccacaaaa 5940 caagtgaaaa tggcctgttc ctgccttaac tgatgacatt ccaccacaaa acaagtgaaa 6000 atggcctgtt cctgccttaa ctgatgacat tatctggtga aattccgtct cctggctcat 6060 cctggctcaa aagctcccct actgaccacc ttgtgacccc cacccctgcc tgccagagaa 6120 taacccccct ttttccttta cctacccaaa tcctataaaa cagccccacc cctatctccc 6180 ctcactgact ctctttttgg actcagccca cctgcaccca ggtgaaataa acagccttgc 6240 tgctcacaca aagcctgttg ggtggtctct tcacacggac gtgcatgaaa actttgaagc 6300 aggcattttg ctgtattatc tcaataacat ttttataaca tgttgaggta gatcttacgt 6360 tcattttaca aatgagaata ctaagatgtg gagagcttaa ccaatttaag cctgaagtta 6420 caatttaata gcaggaaggt ggacaaacgt tttttccgtt ctccaattcc tactgcctcc 6480 taaacatgtt ttacagacat gggcctctta acaatgggac atgccctgag aaatgcatca 6540 ctaggcaatt tctttgttat gtgaacatta cagtgtacct acacaaactt agaaggtata 6600 gcttactaca tacctaggct atatggtaga gcctattcct actaggctac aaatttggaa 6660 acatgtcatt ctactgaata ctgccggcaa ttacaacgca atggtagttg tgtatttaaa 6720 cgtgtctaca catagaaaag ctacaataaa aataacagta ttataatctt acgggaccat 6780 catcatataa gcagcgcatt cctgactgaa atgttggtta ggcagtacat cactgtattt 6840 ctttcattct tagaaaatga agtgaagggg aatataattt attttcatat acctacctct 6900 tctcaacaag ttccttatat tttttggcca taggggaaga ttctaatatt cacatctgaa 6960 tatcaattac ctttaagcaa aatatagtgt cttcataacc cagaacttga aaaatcacaa 7020 aacttgtttt cctggtacat tgtgtcaggc ctctgagccc aagctaagcc atcatgtccc 7080 ctgtgaccca catgtacaca tccagatggc tggttctttc cttaactgac gacattccac 7140 cacacaacaa gtgaaaaatg gcctgttcct gccttaactg atgacattat cttgtgaaat 7200 tccttctcct ggctcatcct ggctcaaaag ctcccctgct gagcacctcg tgaccccccc 7260 actcctgcct gccagagaac aacccccctt tgactgtaat tttcctttac ctacccaaaa 7320 cttataaaac ggccccaccc ctatctccct tcactgactc ttttcggact cagcccgcct 7380 gcacccaggt gaaataaaca gccttgttgc tcacaaaaag cctgtttggt ggtctcttca 7440 cacggacacg actgaaa 7457 <210> 28 <211> 4093 <212> DNA <213> Homo sapiens <400> 28 tgactctctt cggactcagc ccgcctgcac ccaggtgaaa taaacagcca tgttgctcac 60 acaaagcctg tttggtggtc tcttcacacg gacgcgtatg aaatttggtg ccgtgactcg 120 gatcggggga cctcccttgg gagatctatc ccccgtcctc ctgctctttg ctccatgaga 180 aagatccacc tacgacctca ggtcctcaga ccaaccagcc caggaaacat ctcaccaatt 240 tcaaatccgg taagcggcct ctttttactc tcttctccaa cctccctcac tatccctcaa 300 ccccttctcc ttcaccctca gcggcaagtc ccgctttcct gggacagggg caagtacccc 360 tcaacccctt ctccttcacc ctcagcggca agtcctgctt tcctggggca ggggcaagta 420 cccctcaacc ccttctcctt caccctcagc agcaagtccc gctttcctag ggggcaagaa 480 ccccccaatc acttatttct gcaccccaac ctcttatctc tgcgccccaa tcccttattt 540 ccgcaccctg acctcttatt tccgtgcccc aaccccttct ctgcttttct ggagggcaag 600 aaccccccac cccttctccg tgtctctact cttttctctg ggcttgcctc cttcactatg 660 ggtaagcttc caccttccat tcctccctct tctcccttag cctgtgttct caaaaaccta 720 aaacctcttc aactaacacc tgacctaaaa cctaaatgcc ttattttctt ctacaatgct 780 gcttgacccc aatacaaatt cgacagtagt tccaaatagc cggaaaacgg cactttcaat 840 ttttccatcc tacaagatct aaataattat tgtcgtaaaa tgggcaaatg gtctgaggtg 900 cctgacgtcc aggcattctt ttacacatca gtcccttcct agtctctgtg cccagtgcaa 960 ctcgtcccaa atcttccttc tttccctccc gcctgtcccc tcagtcccaa ccccaagcgt 1020 cgctgagtct ttctaatctt ccttttctac agacccatct gacctctccc ctcctcacca 1080 gcccaagcta ggtcccaatt cttcctcagc ctccactcct ccaccctata atccttctat 1140 cacctcccct cctcacacct ggtctggctt acagtttcgt tctgtgacta gccctccccc 1200 acctgcccag caatttattc ttaaaaaggt ggctggagct aaaggcatag tcaaggttaa 1260 tgctcctttt tctttatccc aaatcagaca gcgtttaggc tttttcatca aatataaaaa 1320 cccagcccag ttcatggctc gttcagcagc aaccctgaga cgctttacag ccctagaccc 1380 taaaaggtca aaaggccatc ttattctcaa tatacatttt attacccaat ctgctcccga 1440 cattaaataa aactccaaaa attaaattcc agccctcaaa ccccacaaca ggatttaatt 1500 aacctcgcct tcaaggtgta caataataga aaaaagttgc aattccttgc ctccactgtg 1560 agacaaaccc cagccacatc tccagcacac aagaacttcc aaacgcctga accgcagtgg 1620 ccaggcgttc ctccagaacc tcctcccaca gaagcttgct acaagtgcca gaaatctgac 1680 caccaggcca aggaatgcct gcagcccagg attcctccta agccgtgtcc catctgtgcg 1740 ggaccccact ggaaattgga ctgttcaact cacctggcag ccactcccag agcccctgga 1800 actctggccc aaggctctct gactgactcc ttctcggctt agcagctgaa gactgatgct 1860 ccccgattgc ctcggaagcc ctgtagacca tcatggacgc caagctttgg gtaactctca 1920 cagtggaagg taagtccgtc cccttcttaa tcaatacgga ggctacccac tccacattac 1980 cttcttttca agggcctgtt tcccttgcct ccataactgt tgtgggtatt gacagccagg 2040 cttctaaacc tcttaaaact ccccaactct ggtgccaact tagacaatac tcttttaagc 2100 actccttttt agttatcccc acctgcccag ttcccttatt aggctgagac actttaacta 2160 aattatctgc ttccctgact attcctggac tacagctgta tctcattgcc gcccttcttc 2220 ccaatccaaa gcctcctttg catcctcctc ttatatcccc ccaccctaac ccacaagtat 2280 aagatacctc tactccctcc ttggcgaccg atcatgcacc ccttaccatc tcattaaaac 2340 ctaatcaccc ttaccccact caacgccaat atcccatccc gcagcatgct ttcaaaggat 2400 taaagcctgt tatcacgcgc ctgctacagc atggcctttt aaagcctata aactctcctt 2460 accattcccc cattttacct gtcctaaaac cagacaaggc ttacaggtta gttcaggatc 2520 tgcgccttat caaccaaatt gttttgcctt tccaccctgt ggtgccaaac ccatatgctc 2580 tcctatcctc aatacctccc tctactaccc attattctgt tctagatctc aaacatgctt 2640 tctttactat tcctttgcac ccctcgtccc agcctctctt tgctttcact tagactgacc 2700 ctgacatcca ttaggctcag caaattacca aggctgtact gccgcaaagc ttcacagaca 2760 gcccccatta cttcaatcaa gcccaaattt cttcctcatc tgttacctat ctcggcataa 2820 ttctcataaa aacacacgtg ctctccctgc caatagtgtc cgactgatct ctcaaacccc 2880 agcaccttct acaaaacaac aactcctctc cttcttaggc atggttagcg tggtcggaat 2940 tcttacacaa gagccaggac cacatcctgt agcctttctg tccaaacaac ttgaccttac 3000 tgttttagcc tagccctcat gtctgcgtgc agcggctact gctgctttaa tacttttaga 3060 ggccctcaaa atcacaaact ttatcagtcc tccaggccca agttgactct ttagctgcag 3120 ttgtcctcca aaaccgccga ggccttgact tactgctgaa aaaggaggac tctgcatatt 3180 cttaaatgag gagtgttgtt tttacctaaa tcagtctggc ctggtgtatg acaacataaa 3240 aaaactcaag gatagagccc aaaaacttgc caaccaagaa agtaattacg ctgaaccccc 3300 ttgggcactc tctaactgga tgtcctgggc cctcccaatt cttagtcctt taatacccat 3360 ttttctcctc cttttattcg gaccttgtat cttccgttta gcttctcaat tcatccaaaa 3420 ccgtatccag gtcatcacca atcattttat acgacaaatg tttcttctaa catccccaca 3480 atatcacccc ttaccacaag acctcccttc agcttaatct ctcccactct aggttcccac 3540 gccgccccta atcccacttg aagcagctct gagaaacatc gcccattctc tctccatacc 3600 accccccaaa aattttcgcc actccaacac ttcaacacta ttttgttttg tcttattaat 3660 ataagaaggc aggaatgtca ggcctctgag cccaggcaag gccatcgcat cccctgtgac 3720 ttgcacgtat acatccagat agcctgaagt aactgaagat ccacaaaaga agtaaaaaca 3780 gccttaactg atgacattcc accattgtga tttgttcctt ccccacccta actgatcaat 3840 gtactttgta atctccccca cccttaagaa ggtactttgt agtctccccc acccttaaga 3900 aggttctttg taattctccc cacccttgag aatgtacttt gtgagatcca cccctgcccc 3960 tttgactgta actttccatt accttcccaa atcctataaa acggccccac ccctatctcc 4020 cttcgctgac tctcttttcg gactcagccc acctgcaccc aggtgaaata aacagcttta 4080 ttgctcacaa aaa 4093 <210> 29 <211> 1293 <212> DNA <213> Homo sapiens <400> 29 gtggggaaaa gaaagagaga tcagattgtt actgtgtctg tgtagaagga agtagacata 60 ggagactcca ttttgttctg tactaagaaa aattcttctg cctcgagctg ctgttaatct 120 gtaaccctac ccccaaccct gtgctccctg aaacatgtgc tgtgtcaagt cagggttaga 180 tggattaagg gttgtgcagg gtgtgctttg ttaaacaaat gcttgaaggc agcacgcttg 240 ttaagagtca tcaccggccg ggcgcggtgg ctcacgcctg taatcccagc actttgggag 300 gccgaggcgg gtggatcatg aggtcaggag atcgagacca tcctggctaa caaggtgaaa 360 ccctgtctct actaaaaata caaaaaatta gccgggcgcg gtggcgggtg cctgtagtcc 420 cagctactcg ggaggctgag gcaggagaat ggcatgaacc cgggaagtgg agcttgcagt 480 gagccgagat tgcgccactg cagtccgcag tccggcctgg gcgacagagc gagactccgt 540 ctcaaaaaaa aaaaaaaaaa aaaaaaaaag agtcatcacc actccctaat ctcaaaccac 600 tccctaatct caagtaccca gagacacaaa acactgcgga aggccacaga gacctctgcc 660 taggaaagcc aggtattttc caaggtttct ccccatgtga tagtctgaaa tatggcctca 720 tgggatggga aagacctgac cgtcccccag cccaacaccc gtaaagggtc tgtgctgagg 780 aggattagta aaagaggaag gaacggctct ttgcagttga ggtaagagga aagcttctgt 840 ctcctgctcg tctctgggca atggaatgtc tcggtgtaaa gtccattgta tattccattt 900 actgagatag gggaaaactg ccttagggct ggaggtggga catgctggca gcaatactgc 960 tccttaaggc attgagatgt ttatgtatat gcacatcaaa agcacagcac ttttttcttt 1020 accttgttta tgatgcagag acatttgttc acgtgtttac cttctgacct tctctccact 1080 attatcctat tacccatgcc caataatgat caataaatac taagggaact cagaggccag 1140 tgcccacgtg gatcctctgt atgctgaacg ccggtcccct aggccccctt tttctttctc 1200 tgtactttat ctctgtgtct ctttcttttc caagtctctt gttccaccta acgagaaaca 1260 cccacaggtg tgaaggggca acccacccct tca 1293 <210> 30 <211> 3900 <212> DNA <213> Homo sapiens <400> 30 tgactctctt tttggactca gcccacctgc acccaggtga aataaacagc catgttgctc 60 acacaaagcc tgtttggtgg tctcttcaca cggacgcgca tgaaatttgg tgttgtgact 120 cggatcgggg gacctccctt gggagatcaa tcccctgtcc tcctgctctt tgctcggtga 180 gaaagatcca cctatgacct caggtcctca gactgaccag cccaagaaac atctcaccaa 240 tttcaaatct ggtaagtggc ctctttttac tctcttctcc aacttccctc actatccctc 300 aacctctttc tcctttcaat tttggcgcta cacttcaatc tctcccttct cttaatttca 360 attcctttca ttttctggta gagacaaaag agacacattt tatccgtgga cccaaaactc 420 cggcgccagt cacggactgg gaaggcagcc ttcccttggt gtttaatcat tggagggacg 480 cctctctgat tatacaccca cgtttcaagg gtgtcagacc acgcagggac gcctgccttg 540 gtccttcacc cttagcggca agtcccgctt ttctggggaa ggggcaagta ccccaacccc 600 ttctctcctt gtctctaccc cttctctgcc tttcctgggg caggggcaag tacccctcaa 660 tcccttctcc ttcaccctta gcggcaagtc ccgctttcct aggggcaaga accccccaat 720 cgcttatttc cacaccccaa cctcttatct ctgtgcccca atcccttatt tccgcaccct 780 gacctcttat ctctgtgccc caatccctta tttctgtgcc ccaacccctt ctctgctttt 840 ctggagggca agaacccccc accccttctc cgtgtctcta ctcttttctc tgggcttgcc 900 tccttcacta tgggtaggct tccaccttcc attcctcctt ctcccttagc ctgtgttctc 960 aaaaacttaa aacctcttca actcacacct gacctaaaac ctaaatgctt tattttcttc 1020 tgcaatgccg cttgacccca atacaaactc gacatagttc caaatagctg gaaaacggca 1080 ctttcaattt ttccatccta taagatctaa ataattcttg tcgtaaaatg ggcaaacggt 1140 ctgaggtgcc tgacgtccag gcattctttt acacatctgt cccttcctag tctctgtgcc 1200 cagtgcaact cgttccaaat cttccttctt tccctccctc ctgtcccctc agtcccaacc 1260 ccaagcagtg ctgagtcttt ctaatcttct ttttctacag acccatctga cctctcccct 1320 ccacaccagg ccaagctagg tcccaattct tcctcagcct cagcgcctcc acactgtaat 1380 ctttttatcg ccacccccca ccccctccac cccgcatccc acacctggtc ctgcttacag 1440 tttcattctg tgactagccc tcccccacct gcccagcaat ttactcttaa aaaggtggct 1500 ggagccaaag gcctagtcag ggttaatgct cctttttctt tatcctgaat cagatagcgt 1560 ttaggctctt tttcatcaaa tataaaaatc cagcccactt catggctcat tcggcagcaa 1620 ccctgagacg ctttacagcc ctagacccta aaaggtcaaa aggccgtctt attctcaata 1680 tacattttat tacccaatct gctcccaaca ttaaataaaa ctccaaaaat taaattccgg 1740 ccctcaaacc ccacaacagg atttaattaa cctcaccttc aaggtgtaca ataatagaaa 1800 aaagttgcaa ttccttgcct ccactgtgag acaaacccca gccacatctc cagcacacaa 1860 gaacttccaa atgcctgaac cgcagcggcc aggcgttcct ctagaacctc ctcctccagg 1920 agcttgctac aagtgccaga aatctgacca ccaaggcaag gaacgcctgc agcccaggat 1980 tcctcttaag ccgtatccca tctgtgcggg accccactgg aaatcggact gttcaactca 2040 cctggcagcc actcccagag cccctggaac tctggcccaa ggctctctga ctgactcctt 2100 ctcggcttag cggctgaaga ctgacactgc ccgatcgcct cggaagcccc gtagaccatc 2160 atggacgccg agcttcaggt aactctcaca gtggaaggta agtccgtccc cttcttaatc 2220 aatacggagc ctacccactc cacattacct tcttttcaag ggcctgtttc ccttgcctcc 2280 ataactgttg tgggtattga cagccaggct tctaaacttc ttaaaactcc ccaactctgg 2340 tgccaactta gacaacactc ttttatgcac tcttttttag ttatctccac ctgcccactt 2400 ctcttattag gccgagatat tttaaccaaa ttatctgctt ccctgactat tcctggacta 2460 cagccgcatc tcattgctgc ccttcgtccc aatccaaaac ctcctttgct tcctcctctt 2520 gtattccccc accttaaccc acaagtataa gagacctcta ctccctcctt ggtgactgat 2580 cacgcacccc ttaccatctc attaaaacct aatcaccctt accccgctca acgccaatat 2640 cctatcccac agcacgcttt aaaaggatta aagcctgtta tcactcgcct gctacagcac 2700 gggcttctaa aacctataaa ctctccttac cattccccca ttttacctgt cctaaaacca 2760 ggcaagggtt acaagttagt tcagaatctg caccttatca accaaattgt ttttcctatc 2820 ccccccgtgg tgccaaagcc atatactctc ctatcctcaa tacctccctc tgctacccat 2880 tattctgttc tggatctcaa acatgctttc tttactatcc tttgcacctt catccagcct 2940 ctctttgcct tcacttagac tgaccctgac acccattagg ctcagcaaat tacctgggct 3000 gtactgccgc aaggcttcac agacagcccc cattacttca gtcaagccca aatttcatcc 3060 tcatctgtta cctatctcgg cataattctc ataaaaacac acgtgctctc cctgctgatc 3120 gtgtccgatt aatctcccaa acctcaatcc cttacaaaag aacaactcct ttccttccta 3180 ggcatggtta gtgcggtcag aattcttaca caagagccag gaccacaccg tgtagccttt 3240 ctgtgcaaac aacttgacct tactgtttta gcctagccct catgtctgca tgcagcggct 3300 gccgctgctt taatactgtt agaggcccta aaaatcacaa actatgctca actcactctc 3360 tacatttctc ataacttcca aaatctattt tcttcctcat acctgacgca tatactttct 3420 gctccccggc tccttcagct gtactcactc ttaaatccca caattaccat tgttcctggc 3480 ccggacttca atctggcctc ccacattatt cctgatacca cacctgaccc ccatgactgt 3540 atctctctga tccacctgat attcacccca tttccccata tttccttctt tcctgttcct 3600 caccctgatc acgcttgcct cgtgctatcc ccaaactgcc attcttaact cttgaagtaa 3660 ataaataatc tttgctggca gggctatgct gaatctcctt aggcactctc taatcagatg 3720 tcctgagttg tcccaattct tagacttttt atacctgttt ttctccttct gttattccat 3780 ttagtttttc aattcataca aaaccatatc caggccatca ccaataattc tacacaacaa 3840 atgtttcttc taacaacccc acaatatcac cccttaccac aaaatcttcc ttcagcttaa 3900 <210> 31 <211> 928 <212> DNA <213> Homo sapiens <400> 31 gtggggaaaa ggaggacaga tcagactgtt actgtgtcta tgtagaaaga aatagacata 60 agagactcca ttttgttctg tactaagaaa aattcttctg ccttgagatg ctgttaacct 120 gtaaccctag ccccaaccct gtgctcccag aaacatgtgc tgtgtcacac gtgggtttag 180 ggctatgcag gatgtgcttt gttaaacaga tgcttgaagg cagcatgctt gttaaaagtc 240 atcaccactc tctaatctca agcacccagg gacacaatac actgcggaag gctgcaggga 300 cctctgccta gaaaagccag gtattgtcca aagtttctcc ccatgtgata gcctgagata 360 aggcctcgtg ggaagggaaa gaccagaccg taccccagcc cgacacccgt aaagggtctg 420 tgctgaagag gattagtata agaggaaggc ctttttgcag ttaagaggaa ggtatctgtc 480 tcctgctcgt ccctgggcaa tggaatgtct cggtgtaaaa cccgatggta tgttccatcc 540 accgagatag gggaaaaccg ccttagggct ggaggtgaca catgctggca gcaatactgc 600 tctttaatgc accagatatg tttatgtatg agcacatcaa ggcacagcac atttcctaac 660 cttgtttatg acacagacat ttgctcacat gttttcctgc tgaccctctc cccactgtta 720 ccctattgtc ctgccacatc cccgtctccg agatggtaga gataatgacc aataaatact 780 gaaggaactc agagacccgg ccggcgcggg tctcctgagc ccacttttct ttctgtgtac 840 tttgtctctg tgtctctttc ttttctcagt ctctcgtccc acctgacaag aaacacccac 900 aggtgtggag gggcaggcca ccccttca 928 <210> 32 <211> 327 <212> DNA <213> Homo sapiens <400> 32 tgggtcaggc acaaagtaag cccaccccac caggaactat gttgaaaaat ttcaagaaag 60 gatttaaggg agattatggt gttactctga caccaggaaa agttagaact ttatgtgaaa 120 tagactggcc agcattagag gtggatttcc catcagaagt aagccttgac gggtccgttg 180 tttcaaaggt atggcacaag gtaacctgta agccagggca cgcaaaccag ttcctgtaca 240 tagacacttg gttacagctg gttttagatc cgcctcacag tggttgagag aacagcagca 300 taagcagctg acagaggcaa ggaaaga 327 <210> 33 <211> 3613 <212> DNA <213> Homo sapiens <400> 33 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac gtatatgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aaggccctgc cccgccttaa 120 ctgatgacat tccaccattg tgatttgttc ctgccccacc ttaactgagt gattaaccct 180 gtgaatttcc ttctcctggc taagaaactc ccccactgag caccttgtga cccccgcccc 240 tgccccccag agaacaaccc cctttgactg tcattttcca ttaccttccc aaatcctata 300 aaactcagcc tataagactc agcccgcctg cacccaggtg aaataaacag ccatgttgct 360 cacacaaagc ctgtttggtg gtctcttcac acggatgcgc atgaaatttg gtgcaagaac 420 cccccacccc ttctccgtgt ctctactctt ttctctgggc ttgcctcctt cactatcggt 480 aagcttccac cttccattcc tccttcttct cccttagcct gtgttctcaa aaacttaaaa 540 cctcttcaac tcacacctga cctaaaacct aaatgcctta ttttcttctg caatgccgct 600 tgaccccaat acaaactcga cagtagttcc aaatagccag aaaatggcac tttgaatttt 660 tccatcctgc aaaatctaaa taattcttgt cgtaaaacag gcaaacggtc tgaggtgcct 720 gacgtccagg cattctttta cacatcagtc ccttcctagt ctccttgccc agtgcaactc 780 gtcccaaatc ttcctttccc tctggcctgt cccctcagta ccaaccccaa gcgtcgctga 840 gtctttctaa tcttcctttt ctacagaccc atctgacctc tcccttcctc cccaggctgc 900 tcctcgccag gccgagctag gtcccaattc ttcctcagcc tccgttcctc caccctataa 960 tctttttatc acctcccctc ctcacacctg gtccggctta cagtttcgtt ccatgactag 1020 ccctccccca cctgcccagc aatttactct taaaaagcca aaggcatagt caaggttaat 1080 gctccttttt ctttatccca aatcagatag catttaggct ttttcatcaa atataaaaat 1140 ccagcccagt tcatggctcg tttagcagca atcctgagac actttacaga cctagaccct 1200 aaaaggtcaa aaggccgtct tattctcaat atacatttta ttacccaatc tgctcccgac 1260 attaaataaa actccaaaaa ttggaatctg gccctcaaac cccacaacag gacttaatta 1320 acctcacctt caaggtgtac aataacagaa aaaagttgca attccttgcc tccattgtga 1380 gacaaacccc agccacatct ccagcacaca agaacttcca aacgcctgaa ccgcagcagc 1440 caggcgttcc tccagaacct cctcccccag gagcttgcta cacgtgccgg aaatctggcc 1500 accaagccaa ggaatgcccg cagcccagga ttcctcctaa gccgtgtccc atctgtgcgg 1560 gaccccactg aaaatcggac tgttcaactc acctggcagc cactcccaga gcccctggaa 1620 ctctggccca aggctctctg actgactcct tcccagatct tctcggctta gtggctgaag 1680 actgacactg cccgatcacc tcggaagccc cctagaccat cacggacgcc gagcttcggg 1740 taactctcac agtgggaagt aagcccatcc ccttcttaat caatacggag gctacccatt 1800 ccatattacc ttcttttcaa gggcctgttt cccttgcctc cataactgtt gtgggtattg 1860 acggccaggc ttctaaacct cttaaaactc cccaactctg gtgccaactt agacaatact 1920 cttttaagca ctccttttta gttatcccca cctgcccagt tcccttatta ggctgagaca 1980 atttaactaa attatctgct tccctgacta ttcctggact acagctatat ctcattgccg 2040 cccttcttcc caatccaaag cctcctttgc gtcctcctct tgtatccccc caccttaacc 2100 cacaagtata agatacctct actccctcct tggcgaccga tcatgcaccc cttaccatct 2160 cattaaaacc taatcaccct taccccactc aacgccgata tcccatcccg cagcacgctt 2220 taaaaggatt aaagcctgtt atcactcgcc tgctacagca tgggctttta aagcctataa 2280 actctcctta caattccccc attttacctg tcctaaaacc agacaagcct tacaagttag 2340 ttcaggatct gcgccttatc aaccaaattg ttttgactat ccaccccgtg gtgccaaacc 2400 catatactct cctatcctca atacctgcct ctataaccca ttattctgtt ccagatctca 2460 aatatgcttt ctttactatt cctttgcacc cttaatccca gcctctcttc actttcactt 2520 ggactgaccc tgacgcccat caagctcagc aaattaccta gtctgtactg ctgcaaagct 2580 tcacagacag cccccattac ttcagtcaag cccaaatttc atcctcatct gttagtcata 2640 ctcctattca ccgttctcaa ctactcatac atgccctgct cttgtttaca ctgccggttt 2700 acactgtttc tccaagccat cacagctgat atctcccagt gctatcccca aactgccact 2760 ctaaactctt gaagtaaata aataatcttt gctggcagga ctatgctgaa tctccttagg 2820 cactctctaa ttagatgccc taggtcctcc caattcttag tccttttata cctgtttttc 2880 tcctactctt attccattta gtttttcaat tcatacaaaa ccatatccag gccatcacca 2940 atcattctat acaacaaatg tttcttctta catccccaca atatcacccc ttaccacaag 3000 atctcccttc agcttaatct ctcccactct aggttcccac accgccccta atcccgcttg 3060 aaacagccct gagaaacatc gcccattctc tctccatacc accccccaaa atttttcgcc 3120 gccccaacac ttcaacacta ttttgtttta tttttcttat taatataaga aggcaggaat 3180 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac gtatacgccc 3240 agatggcctg aagtaactga agaatcacaa aagaaatgaa aaggccctgc cccgccttaa 3300 ctgatgacac tccaccattg tgatttgttc ctgccccacc ttaactgagt gattaaccct 3360 gtgaatttcc ttctcctggc tcagaagctc ccctactgag catcttgtga cccccgcccc 3420 tgccccccag agaacaaccc cctttgactg taattttcca ttaccttccc aaatcctata 3480 aaacggcccc atccctatct cccttcgctg actctctttt cggactcagc ccgcctgcac 3540 ccaggtgaaa taaacagcca tgttgctcac acagagccta tttggtggtc tcttcacacg 3600 gacgtgcatg aaa 3613 <210> 34 <211> 290 <212> DNA <213> Homo sapiens <400> 34 gacttggatc ggggggcctc ccttgggaga tcaatccccc gtcctcctgc tttttgctcc 60 ttgagaaaga tccacctagg acctcaggtc ctcagaccga ccagcccaag atacatctca 120 ccaatttcaa atccgccact cccagagccc ctggaactct ggcccaaggc tctctgactc 180 cttcccagat cttctcggct tagcggctga agactgacac tgcccgatcg cctcggaagc 240 cctctacccc atcacggacg ccgagctttc ggtaactctt acggtggaag 290 <210> 35 <211> 3653 <212> DNA <213> Homo sapiens <400> 35 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac gtgtacgccc 60 agatggcctg aaataactga agaatcacaa aagaagtgaa tatgccctgc cccaccttaa 120 ctgatgacat tccacaacaa aagaagtgta aatggctggt ccttgcctta actgatgaca 180 ttaccttgtg aaagtccttt tcctggctca tcctggctca aaaagcaccc ccactgaaca 240 ccttgtgacc cccattcctg cccgccagag aacaaaccct ctttgactgt aattttcctt 300 tacctaccca aatcttataa aacggcccca cccttatctc ccttcactga ctctcttttc 360 ggactcagcc cgcctgcaac caggtgaaat aaacagccat gctgctcaca caaagcctgt 420 ttggtgctct cttcacacag atgcgcatga aatttggtgc cgtgactcag atcaggggac 480 ctcccttggg agatcaatcc cctgtactcc tgttctttgc tccgtgagaa agatccacct 540 atgacctcag gtcctcagac ctaccagccc aaggaacatc tcaccaattt taaatcaggt 600 aagcggcctc ttcttactct cttctccaac ctctctcact gtccctcaac cactttctcc 660 tttccaatct tcaatctctc ccttctctta atttcaattc ctttcatttt ctaggagaga 720 caaaggagat gcattttatt cgtggaccca aaactccggt gccagtcacg gactgggaag 780 gcagccttct cttggtgttt aatcattgca gggacacctc tctgattata cacccacatt 840 tcaagggtgt cagaccacgc agggacacct gccttggtcc ttcaccctta gcggcaagtc 900 ccgcttttct gaggaaggga caagtacccc aaccccttct ctccttgtct ctaccccttc 960 tctgcttttc tgggagaggg gcaagtaccc ctcaaccctt tctccttcac ccttagcggc 1020 aagtcccgct tttctacggg gcaagaaccc ccaatccctt atttctgcgc cacaacctct 1080 tatctctgtg ccccaatccc ttatttccat accccgacct cttatctctg cgccccaatc 1140 ccttatttcc atacgccgac ctcttatctc tgtgccccaa tcccttattt ctgcgcccca 1200 acctcttata tctctgtgcc ccaatccctt atttctgtgc cctgacctct tatctctgtg 1260 ccccaacccc ttttcccact tttctgggag gtaagaaccc ccgaacccct tccctccatt 1320 tctctactct ctctcttctc taggcttgct tccttcacta taggcaactt tccaccctcc 1380 attcctcctt ctactccctt ggcctgtgtt ctcaaaaact taaaacctct tcaactcaca 1440 cctgacctaa aacctaaatg ccttattttc ttctgcaatg ctgcttgtcc ccaataccaa 1500 ctcgacagta gttccaaata gccagaaaat ggcactttga atttttccat cctgcaaaat 1560 ctaaataatt cttgtcgtaa aataggcaaa cggtctgagg tgcctgacgt ctaggcattc 1620 ttttacacat cagtcccttc ctagtctctg tgcccagtgc aactcgtccc aaatcttcct 1680 tctttccctc ccacctgtcc cctcagtacc aaccccaagc gtcgctgagt ctttctaatc 1740 ttccttttct gcagacccat ctgacctctc ccttcctccc caggctgctc ctcgccaggc 1800 cgagctaggt cccaattctt cctcagcctc tgctcctcca ccctataatc tttttatcac 1860 ctcccctcct cacacctggt ccggcttaca gtttcgttcc gtgactagcc ctcccccacc 1920 tgcccagcaa tttactctta aaaaggtggc tggagccaaa ggcatagtca aggttaatgc 1980 tcctttttct ttatcccaaa tcagatagcg tttaggctct ttttcatcaa atataaaaat 2040 ccagcccagt tcatgacttg tttggcagca accctgagac gctttacagc cctagaccct 2100 aaaaggtcaa aaggccatct tattctcaaa atacatttta ttacccaatc tgctcccgac 2160 attaagtaaa actccaaaaa ttggaatctg gccctcaaac cccaaaacag gacttaatta 2220 acctcacctt caaggtgtac aataacagaa aaaagttgca attccttgca tccactgtga 2280 gacaaacccc agccacatct ccagcacaca agaacttcca aacacctgaa ccgcagcagc 2340 caggcattcc tgcagaacct cctcccccag gagcttgcta caagtgccag aaatctggcc 2400 actgggccaa ggaatgcctg cagcccagga ttcctcctaa gctgcgtccc atctgtgtgg 2460 gaccccactg aaaatcggac tgttcaactc acctggcagc cactcccaga gcccctggaa 2520 ctctggccca agcctctctg actgactcct tcccagatct tctcggctta gcggctgaag 2580 actgacactg ccggatcacc tcggaagccc cctagaccat cacggatgcg gagcttcagg 2640 taactctcac agtggaaggt aagcccgtcc ccttcttaat caatacggag gctacccact 2700 ccacattacc ttcttttcaa gggcctgttt cccttgcctc cataactgtt gtgggtattg 2760 atggccaagc ttctaaacct cttaaaactc cccaactctg gtgccaactt agacaatact 2820 cttttaagca ctccttttta gttatcccca cctgcccagt tcccttatta ggctgagaca 2880 ctttaactaa attatctgtt tccctgacta ttcctggact acagctatat ctcattgcca 2940 cccttcttcc caatccaaag cctcctttgc gtcctcctct tgtatccccc aaccttaacc 3000 cacaagtata agatacctct actccctcct tggcgaccga tcatgcaccc cttaccatct 3060 cattaaaact taatcaccct taccccactc aatgccaata tctcatccca cagcacgctt 3120 taaaaagatt aaaagcctgt tatcactcgc ctgctactgc atggcctttt aaagcctata 3180 aactctcctt acaattcccc cattttacct gtcctaaaac cagacaagcc ttacaagtta 3240 gttcaggatc tgcgccttat caaccaaatt gttttgccta tccaccctgt ggtgccaaac 3300 ccatatactg tcctcaatac gtgcctctac aacccattat tctgttctaa atctcaaaca 3360 tgcttttttc actattcctt tgcaccctta atcccagcct ctcttcgctt tcacttggac 3420 tgaccctgac acccatcaag ctcagcaaat tacctaggct gtactgccgc aaagcttcac 3480 agacagcccc cattacttca atcaagccca aatttcttcc tcatctgtta cctatctcgg 3540 cataattccc ataaaaacac acgtgctctc cctgccaatc atgtctgact gatctctcaa 3600 accccagcac ctcctacaaa acaacaactc ctttccttcc taggcgtggt tag 3653 <210> 36 <211> 6271 <212> DNA <213> Homo sapiens <400> 36 gtcaggcctc tgagcccaag ccaagccatc acatcccctg tgtcttgcac ctatacgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa tatgccctgc cccaccttaa 120 ctgatgacat tccaccacaa aagaagtgta aatggccggt ccttgcctta agtgatgaca 180 ttaccttgtg aaagtccttt tcctggctca tcctggctca aaaagcaccc ccactgagca 240 ccttgcgacc ccgactcctg cccgccagag aacaaacccc ctttgactgt aattttccgt 300 tacctaccca aatcctataa aacagcccca cccttatctc ccttcactga ctctcttttc 360 ggactcagcc cgcctgcacc caggtgaaat aaacagcctt gttgctcaca caaagcctgt 420 ttggtggtct cttcacacgg acgcgcatga aatttggtcc cagtcaggcc tctgagccca 480 agccaagcca tcgcatgccc tgtgacttgc acatgtatgc ccagatggcc tgaagtaact 540 gaagaatcac aaaagaagtg aatgtgccct gccccgcctt aactgatgac attccaccac 600 aaaagaagtg aaaaaggccg gtccttgcct taagtgatga cattaccttg tgaaagtcct 660 tttcctggct catcctggct caaaaagcac ccccactgag caccttgcga cccccactcc 720 tgcctgccag agaacaaacc ccctttgact gtaattttcc tttacctacc caaatcctat 780 aaaacagccc cacccttatc tcccttcact gactctcttt tcggactcag cccgcctgca 840 cccaggtgaa ataaacagcc ttgttgctca cacaaagcct gtttggtggt ctcttcacac 900 ggacatgcat taaatttggt gccgtgactc agatcagggg acctcccttg ggaaatcaat 960 cccctgtcct cctgctcttt gctccgtgag aaagatccac ctacgacctc aggtcctcag 1020 accaaccagc ccaagaaaca tctcaccaat ttcaaatcca gtaagccgcc tctttttact 1080 ctcttctcca acctccctca ctatccctca gcctctttct cctttcaatc ttggtgccac 1140 acttcaatct ctcccttctt ttaatttcaa ttcctttcat tttctggtag agacaaagga 1200 gacatgtttt atccctggac ccaaaactct ggcgccggtc acggactagg gaaggcagct 1260 ttcccttggt gtttaatcat ttcagggaca cctctctgat tatttaccca ggtttcagag 1320 gtgtcagacc acgcagggat gcctgccttg gtccttcacc cttagtggca agtcctgctt 1380 ttctggggaa ggggcaagta ccccaacccc ttctctccgt gtctctaccc cttctctgcc 1440 tttctggggg gcaagaaacc cccaaccctt tctccttcac cctgagtggc aagtcccact 1500 tttctagagg aggggaaagt accccaacct catatctctg cacctcaatc ccttatttcc 1560 acaccccaac ctattatctc tgtgccccaa tcccttattt ccatgcccca acctcttatc 1620 tctgcaccac aatcccttat ttccatgccc cgacatctta tgtctccacg ccctgacctc 1680 gtatctctgc accccgaccc ctttcctgct tttctggagg gtaagaaccc ctgaaccgct 1740 tccctccgtg tctctactct cccttttctt taaacttgcc tccttcacta taggcaacct 1800 tccaccctcc attcctcctt cttctctctt agcctgtgtt ctcaaaaact taaaacctct 1860 tcaactcaca cctgacctaa aacctaaatg ccttattttc ttctgcaatg ccgcttgacc 1920 ccaatacaaa ctcaacagta gttccaaata gccggaaaac agcactttca atttttccat 1980 cctgcaagat ctaaataatt cttgtcgtaa aatgggcaaa cggtctgagg tgcctgacgt 2040 ccaggcattc ttttacacat cggtccctcc ccagtctctg tgcccaatgc aactcatccc 2100 aaatcttcct tctttccctc ccacctgtcc cctcagtccc aaccccaagc atcactgagt 2160 ctttctaatc ttccttttct acagacccat ctgacctctc ccctcctccc caggctgctc 2220 ctcaccaggc cgagctaggt cccaagtctt cctcagcctc cgctcctcca ccctataatc 2280 cttttatcac ctcctctcct cacacccagt ccggtccggc ttacagtttc attccgtgac 2340 tagccctccc ccacctgcca gcaatttact cttaaaaagg tggctggagc taaaggcata 2400 gtcaaggtta ttgctccttt ttctttatcc caaatcagat agcgtttagg ctctttatca 2460 atataaaaat ccagcccagt tcataacttg tttggcagca accctgagac actttacagc 2520 cctagaccct aaaaggtcaa aaggccgtct tattctcaaa atacatttta ttacccaatc 2580 tgctcctgac attaaataaa actccaaaaa ttaaattcca gccctcaaac cccacaacag 2640 gatttaatta acctcgcctt caaggtgtac aataatagaa aaaagttgca attccttgcc 2700 tccactgtga gacaaacccc aaccacatct ctagcacaca agaacttcca aatgcctgaa 2760 ccgcagcggc caggcgttcc tccagtaccg cctcccccag gagcttgcta caagtgccag 2820 aaatctggcc accaggccaa ggaatgcctg cagcccagga ttcctcctaa gccgcgtccc 2880 atctgtgcga gaccccactg gaaatcggac tgtccaactc acctggcagc cactcccaga 2940 gcccctggaa ctctggccca aggctctctg actccttccc agatcttctt ggcttagcgg 3000 ctgaagactg acgctgccca gtcgcctcgg aagcccccct acatcatgga cgctgagctt 3060 cagataactc tcacagtgga aggtaagtcc gttcccttct taatcaatac ggaggctacc 3120 cactccacat taccttcttt tcaaaggcct gtttccctca cctccataac tgttgtaggt 3180 attgacggca aggcttctaa acctcttaaa acttcccaac tctggtgcca acttagacaa 3240 tactctttta agcactcctt ttagttatcc ccacctgccc agttccctta ttaggcggag 3300 acactttaac taaattatct gcttccctga ctattcctgg gctacagcca cacctcattg 3360 ctgcccttct tcccaatcca aagcctcctt tgtgtcctcc tcttgtatcc ccccacctta 3420 acccacaaat ataagatacc tctactccct ccttggcgac cgatcatgca ccccttacca 3480 tcccattaaa acctcatcac ccttaccccg ctcaatgcca atatcccatc ccacagcatg 3540 ctttgaaagg attaaagcct gttatcactc gcctgctaca gcatggcctt ttaaagccta 3600 taaactctcc ttacaattcc cccattttac ctgtcctaaa accagacaag ccttacaagt 3660 tagttcagga tctgcgcctt atcaaccaaa ttgttttgcc tatccacccc gtgctgccaa 3720 acccatatac tctcctatcc tcaatacctg cctctacaac ccattattct gttctagatc 3780 tcaaacgtgc tttctttact attcctttgc acccttaatc ccagcctctc ttcgctttca 3840 ctttgactga ccctgacacc catcaagctc agcaaattac ctgggctgta ctgccgcaaa 3900 gcttcacaga cagcccccat tacttcaatc aagcccaaat ttcttcctca tctgttacct 3960 gtctcagcat aattctcata aaaacacacg tgctctccct accaatcgtg tccgactgat 4020 ctctcaaacc ccagcacctt ctacaaaaca acaactcctt tccttcctag gcctggttag 4080 cacggtcaga attcttacac aagagccagg accacaccct gtagcctttc tgtccaaaca 4140 acttgacctt actgttttag cctagccctc atgtctgcgt gcagcggctg ccactgcatt 4200 aataccttta gaggccctca aaatcacaaa ctatgctcaa ctcactctct acagttctca 4260 taacttccaa aatctatttt cttcctcata cctgacacat actttctttt tcccggctcc 4320 ttcagctata ctcactcttt gttgagtctc ccacaattac cattgttcct ggcccagact 4380 tcaatctggc ctcccacatt attcctgata ccacacctga cccccatgac tgtatctctc 4440 tgatccacgt gacattcacc ccatttcccc aaatttcctt ctttcctgtt cctcaccctg 4500 atcacgcttg atttattgat ggcggttcca ccaggcctta tcgccacaca ccagcaaagg 4560 caggctatgc tatggtacaa gccactagcc cacctctcag aacctctcat ttcctttcca 4620 tcgtggaaat ctatcctcaa agaaataact tctcagtgtt ccatctgcta ttctactact 4680 cctcaaggat tattcaggcc ccctcccttc cctacacatc aagctcaagg atttgcccca 4740 accaggactg gcaaattagc tttactcaac atgccctgag tcagataact aaaatacctc 4800 ttagtctagg tagatacttt cactggatag gtagaggcct ttcctacagg gtctgagaag 4860 tcctcctcag tcatttcttc ccttctgtca gacatagttc ctcagtttag ccttcccacc 4920 tcaatgcagt ctgataacag accagccttt attagtcaaa tcagccaagg agtttttcag 4980 gctcttagta ttcagtgaaa cctttatatc ccttacggtc ctccgtcttc aagaaaagta 5040 gaatggacta aaggtctttt aaaaacacac ctcaccaagc tcagccacca acttaaaaag 5100 gactggacaa tacttttacc actttccctt ctcagaattc aggcctgtcc tcggaatgct 5160 acagggtaca gcccatttaa gctcctgtat agacgctcct ttttattagg ccccagtctc 5220 attccagaca ccagaccaac ttagactgtg cccccaaaaa acttgtcatc cctactatct 5280 tctgtctagt catactccta ttcaccattc tcagctactc atacatgccc tgctcttgtt 5340 tacactgccg gtttacactg tttttccaag ccatcacagc tgatatctcc tggtgctatc 5400 cccaaactgc cactcttaac tcttgaagta aataaataat ctttactggc aggactatgc 5460 tgaatctcct taggcactct ctaatcagat accctaggtc ctcccaattc ttagacattt 5520 tatacctgtt tttctcctct gttattccat ttagtttctc aattcatcca aaaccgtatc 5580 caggccatca ccaatcattc tatacgacaa atgtttcttc taacattccc acaatatcac 5640 cccttaccac aagacctccc ttcagcttaa tctctcccac tttaggttca cctaatcccg 5700 cttgaagcag ccctgagaaa cattgcccat tctctctcca taccaccccc caaaaatttt 5760 cgccacccca acacttcaac actattttat ttttcttatt aatatgagaa ggcaggaatg 5820 tcaggcctct gagcccaagc caagccatcg catcccctgt gacttgcacc tatacgccca 5880 gatggcctga agtaactgaa gaatcacaaa agaagtgaat atgccctgcc ccaccttaac 5940 tgatgacatt ccaccacaaa agaagtgtaa atggccggtc cttgccttaa gtgatgacat 6000 taccttgtga aagtcctttt cctggctcat actggctcaa aaagcacccc cactgagcac 6060 cttgcgaccc cgactcctgc ccgccagaga acaaaccccc tttgactgta attttccttt 6120 acctacccaa atcctataaa acagccccac ccttatctcc cttcgctgac tctcttttcg 6180 gactcagccc gcctgcaccc aggtgaaata aacagccttg ttgctcacac aaagcctgtt 6240 tggtggtctc ttcacacgga cgcgcatgaa a 6271 <210> 37 <211> 6158 <212> DNA <213> Homo sapiens <400> 37 gtcaggcctc tgagcccaag ccaagccatc acatccccta tgacttgcat gtatacaccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa tatgtcctgc cccaccttaa 120 ctgatgacat tccaccacaa aagaagtgta aatggctgat ccttgcctta agtgatgaca 180 ttaccgtgcg aaagtccttt tcctggctca tcctggctca aaaagcaccc ccactgagca 240 ccttgcaacc cccactcctg cccgccagag aaaaaacccc ctttgactgt aattttcctt 300 tacctaccca aatcctataa aacagcccca cccttatctc tctttgctga ctctcttttc 360 agactcagcc agcctgcacc caggtgaaat aaacagccat gttgctcacg caaagcctgt 420 ttggtggtct cttcaaacag acgtgcatga aatttggtgc cctgactcgg atcgggggac 480 ctcccttggg agatcaatcc cctgtacttc tgttctttgc tccatgagaa agatccacct 540 atgacctcag gtcctcagac caaccagccc aaggaacatc tcaccaattt taaatcaggt 600 aagcggcctc ttcttactct cttctccaac ctctctcact gtccctcaac cactttctcc 660 ctttcactct tcaatccctc ccttctctta atttcaattc ctttcatttt ctgggagaga 720 caaaggagac acattttatc cgtggacaca aaactccagc gccggtcaca gactgggaag 780 gcagccttcc cttggtgttt aatcattgca gggacgcgtc tctgattata cacccacctt 840 tcaagggtgt cagaccacgc aggaatgcct gccttggtcc ttcaccctta gcggcaagtc 900 ccacttttct ggggaagggg caagtacccc aaccccttct ctccttgtct ctaccccttc 960 tctgcttttt tgggagaggg gcaactattc ctcaacccct tctcctgcac ccttagcggc 1020 aagtcccgct tttctacggg gcaagaaccc ccaatccctt atttccacgc cccaacctct 1080 tatctctgtg ccccaatccc ttatttctgc accccaacct cttttctctg tgccccaatc 1140 ccttatttct gcaccccaac ctcttatctc tgtgccccaa tcccttattt ctgcacccca 1200 acctcttttc tctgtgcccc aatcccttat ttctgcaccc caacctctta tctctgtgcc 1260 ccaatccctt atttctgcac cccaacctct tttctctgtg ccccaatccc ttatttctgc 1320 accccaacct cttatctctg tgccccaatc ccttatttct gcaccccaac ctcttttctc 1380 tgtgccccaa tcccttattt ccacaccccg acctcttatc tctctgccct aatcccttat 1440 ttctgcaccc cgacctctta tctctgtgtc ccaatccctt atttctgagc cccaacctca 1500 tatctctgca ccccaacccc ttatttctgt gccccaacct tttatatctc tgtgccccaa 1560 tcccttattt ctgcacccca accacttttc ccacttttct ggaagataag aacccccaaa 1620 tcccttccct ccgtttctct actctctctt ttctctaggc ttccttcctt cactatgggc 1680 aaccttccgc cctccattcc tccttctact cccttggcct gtgttctcaa aaacttaaaa 1740 cctcttcaac tcacacctga cctaaaacct aaatgcctta ttttcttctg caatgccgcc 1800 tgaccccaat acaaactcaa cagtagttcc aaatagccag aaaatggcac tttgaatttt 1860 tccatcctgc aagatctaaa taattcttgt cgtaaaatag gcaaacggtc tgaggtgcct 1920 gacgtccagg cattctttta cacatcagtc ccttcctagt ctctgtgccc agtgcaactt 1980 gtcccaaatc ttccttcttt ccctcctgcc tgtcccccca gtaccaacac caagcgtcgc 2040 tgagtctttc taatcttcct tttctacaga cccatctgac ctctcccttc ctccccaggc 2100 tgctcctcgc caggccgagc taggtcccaa ttcttcctca gcctccgctc ctccacccta 2160 taatcctttt atcacctccc ctcctcacac ctggtctggc ttacagtttc gttctgtgac 2220 tagccctccc cctcctgccc agcaatttac tcttaaaaag gtggctagag ctaaaggcat 2280 agtcaaggtt aatgctcctt tttctttatc ccaaatcaga tagcatttag gctctttttc 2340 atcaaatata aaaacccagc ccagttcatg gctcgtttgg cagcaaccct gagacgcttt 2400 acagccctag accctaaaag gtcaaaaggc cgtcttattc tcaatataca ttttattacc 2460 caatctgctc ccaacattaa ataaaactcc aaaaactgga atttggccct caaaccccac 2520 aacaggactt aattaacctc accttcaagg tgtgcaataa cagaaaaaaa gttgcaattc 2580 cttgcctcca ctgtgagaca aagcccagac acatctccag cacacaagaa tttccaaacg 2640 cctgaaccat agcagccagg cgttcctcca gaacctcctc ccccaggagc ttgctacaag 2700 tgccagaaat ctgatcacca ggccaaggaa tgcctgcagc ccaggattcc tcctaagccg 2760 tgtcccatct gtgtgggacc ccactggaaa ttggactgtt caactcacct ggcagccact 2820 cccagagccc ctggaactct ggcccaaggc tctctgactg actccttctt ggcttgccgg 2880 ctgaagaccg acgctgcctg atcacctcag aagccccgta gaccatcacg gacgccgagc 2940 tttaggtaac tcacagtgga gtgtaagtcc gtccccttct taatcaatac ggaggctacc 3000 cactccacat taccttcttt tcaagggcct gtttcccttg cccccataac tgttgtgggt 3060 attgacagcc aggcttctaa accttttaaa actcccccac tctggtgcca acttagacaa 3120 caccctttta tgcactcttt tttagttatc tccacctgcc cagttccctt attaggccga 3180 gatattttaa ccaaattatc tgcttccctg actattcctg gactacagcc acatctcatt 3240 gccgcccttc tccccaaccc aaagcctcct tcgagtcttc ctctcatatc cccccacctt 3300 aacccgcaag tataggatat ctctactcct tccctggcaa ctgatcacag gcccattacc 3360 atcccattaa agcctaatca cccttacccc actcaatgcc aatatcccat cccacagcac 3420 gctttgaaag gattaaagcc tgttaacact cgcctgctac agcatggcct tttaaagcct 3480 ataaactctc cttaccattc ccccatttta agtgtcctga aaccagacaa ggtttacaag 3540 ttagttcaga atctgcgcct tatcaaccaa attgttttgc ctatccaccc cgtggtgcca 3600 aacccatata ctctcctatc ctcaatacct ccctctacta cccattattc tgttctatat 3660 ctcaaacatg ctttctttac tattcctttg cacccttcat cccagcctct ctttgctttc 3720 acttatactg accctgacac ccattaggct cagcaaatta cctgggctgt actgccacaa 3780 ggcttcacag acagccccca ttacttcaat caagcccaaa tttcttcctc atctgttacc 3840 tatctcggca taattctcat aaaaacacac gtgctttccc tgctgattgt gtctgattaa 3900 tctcccaaac ctcaatccct tacaaaacaa caactccttt ccttcctagg catggttagt 3960 gtggtcagaa ttcttacaga agagccagga ccgcaccctg tagcctttct gtccaaacaa 4020 cttgaccttg ctgttttagc ctagccctca tgtctgcgtg cagcggctgc cgctgcttta 4080 atacttttag aggccctaaa aatcacaaac tatgctcaac tcactctcta catttctcat 4140 aacttccaaa atatattttc ttcctcatat ctgacgcata tactttctgc ttcccggctc 4200 cttcagctgt actcactctt tgttaagtcc cacaattacc attgttcctg gccgggactt 4260 caatctggcc tcccacatta ttcctgatac cacacctgac ccccatgact gtatctctct 4320 gatccacctg atattcaccc catttcccca tatttccttc ttttcctgtt cctcaccctg 4380 atcacgcttg atttattgat ggcagttcca ccaggcctaa tcgccacata ccagcaaagg 4440 caggctatgc tatagtacaa gccactagcc tgcctcttag aacctctcat ttcctttcca 4500 tcgtggaaat ctaccctcaa ggaaataact tctcagtgtt ccatctgcta ttctactcct 4560 cagggattat tcagaccccc tcccttccat acacgtcaag ctcgaggatt tgcccccacc 4620 caggactggc aaattagctt tactcaacat gcccaagtca ggaaactaaa atacctctta 4680 gtctaaataa acactttcac tgaataagta aaggcctttc ctacagggtc tgagaaggcc 4740 accacagtca tttcttccct tctgtcagac ataattcctc agtttagcct tcccacctct 4800 atacagtctg ataacagacg agcctttatt actcaaatca gccaattagt ttttcaggct 4860 cttagggttc agtgaaacct tcatatccct tacggtcctc catcttcaag aaaagtagaa 4920 cggactaaag atcttttaaa gacacacctc aataagctca gccaccaact taaaaaggac 4980 tggacaatac ttttaccact ttcgtttctc agaattcagg cctgtcctca gaatgctaca 5040 gggtacagcc catttaagct cctgtataga tgctcctttt tattaggccc cagtctcatt 5100 cgacaccaga ccaacttaga ctgtgcccca aaaaaacttg tcatccctac tatcttttgt 5160 ctagtcatac tcctattcac cattctcaac tactcataca tgccctgctc ttgttttcac 5220 tgctggttta cactgttttt ccaagccatc acagctgata tctcctggtg ctatccccaa 5280 actgccactc ttaactcttg aagtaaataa ataatctttg ctggcaggac tatgctgaat 5340 ctccttaggc actctctaat cagatatcct gagtcatccc aattcttaaa ccttttatgc 5400 ctgtttttct ccttctgtta ttccatttag tttttcaatt cgtacaaaac cgtatccagg 5460 ccatcaccaa tcattctata cgacaaatgt ttcttctaac atccccacaa tatcacccct 5520 taccacaagg cctcccttca gcttaatctc tcccactcta ggttcccacg ccacccctaa 5580 tcccgcttga agcagccctg agaaacatcg cccattctgt ctccatacca ccccccaaaa 5640 attttcgccg ccccaacact tcaacactat tttgttttat ttttcttatt aatataagaa 5700 ggcaggaatg tcaggcctct gagcccaagc caagccatca catcccctgt gacttgcatg 5760 tatacaccca gatggcctga agtaactgaa gaatcacaaa agtgaatatg ccctgcccca 5820 ccttaactga tgacattcca ccacaaaaga agtgtaaatg gccggtcctt gccttaagtg 5880 atgacattac cttgtgaaag tcctcttcct gcctcatcct ggctcaaaaa gcacccccac 5940 tgagcacctt gcaaccccca ctcctgcccg ccagagaaca aacccccttt gactgtaatt 6000 ttcctttacc tacccaaatc ctgtaaaacg gccccaccct tatttccctt tgctgactct 6060 cttttcggac tcagcctgcc tgcacccagg tgaaataaac agccatgttg ctcacacaaa 6120 gcctgtttgg tggtctcttc acacggacgt gcatgaaa 6158 <210> 38 <211> 6004 <212> DNA <213> Homo sapiens <400> 38 gtcaggcctc cgagcccaag ccaagccatc gcatcccctg tgacttgcac gtatatacgc 60 ccagatggcc tgaagtaact gaagaatcac aaaagaagtg aatatgccct gccccacctt 120 aactgatgac attccaccac aaaagaagtg taaatggccg gtccttgcct taactgatga 180 cattaccttg tgaaagtcct tttcctggct catcctggct caaaaagcac ccccactgag 240 caccttgcga cccccactcc tgcccgccag agaacaaccc ccctttgact gtaattttcc 300 tttacctacc caaatcctat aaaatggccc catccttatc tcccttcgct gactctctct 360 tcggactcag cccgcctgca cccaggtgaa ataaacagcc atgttgctca cacaaagcct 420 gtttggtggt ctcttcacat ggacgcgcat gaaatttggt gctgtgactc ggatggggga 480 cctcccttgg gagatcaatc ccctgtactc ctgttctttg ctccgtgaga aagatccacc 540 tatgacctta ggtcttcaga ccgaccagcc caagaaacat ctcaccaatt tcaaatctgg 600 taagcggcct ctttttaccc tcttctccaa cctccctcac tatccctcaa cctctttctc 660 ctttcaatct tggcgccaca cttcaatctc tcccttctct taatttcaat tcctttcatt 720 ttctgataga gacaaaggag acatgtttta tccatggacc caaaactccg gcgccggtca 780 cggactggga agacagcctt cccttggtgt ttaatcattg cagggacgcc tctctattca 840 cccacgtttc aaaggtgtca gaccacgcat ggacgcctgc cttggtcctt cacccttagc 900 ggcaagtccc gcttttctgg ggaaggggca agtaccccaa ctccttctct ccttgtctct 960 accccttctc tgctttccga ggaaagggcg agtatcccaa ccccttctct ccttgtctct 1020 actccttctc tgcttttctg ggagaggggc aagtacccct caaccccttc tccttcactc 1080 ttagtggcaa gtcccgcttt tctagaggag ggacaagtgc cccaacctcg tatctctgtg 1140 ccccaatccc ttatttccgt gccccaacct cttatatctc tgcaccccaa tcccttattt 1200 cagtgtccca accccttatt tccgtgcccc gaccccttat ttctgtgccc ctacccctta 1260 tttccgtgcc cctaccccct atttctgtgc ccctacccct tatttccgtg ccccttcccc 1320 ttatttccat gccctgaccc cttatttctg cgccccatcc cttatttctg catcccaacc 1380 tcttatctct gtgccccgac ctcttatctc tgcgccccaa ccccttttcc cacttttctg 1440 gaaggtaaga acccccgaac cccttccctc tgtttttctc tcttttctct aggcttgctt 1500 ccttcactat aggcaacctt ccaccctcca ttcctccttc tgctcccttg gcctgtgttc 1560 tcaaaaactt aaaacctctt caactcacac ctgacctaaa acctaaatgc cttattttct 1620 tctgcaatgc cgcttgaccc caatacaaac tcgacagtag ttccaaatag ccagaaaatg 1680 gcactttgaa tttttctatc ctgcaagatc taaataattc ttgtcataaa ataggcaaac 1740 ggtctgaggt gcctgacgtc caggcattct tttacacatc agccccttcc tagtctctgt 1800 gcccagtgca acttgtccca aatcttcctt ctttccctcc cgcctgtccc ctcagtacca 1860 accccaagca tcactgagtc tctctaatct tccttttcta cagacccatc tgacctctcc 1920 cttcctcccc aggctgctcc tcgccaggcc gagctaggtc ccaattcttc ctcagcctcc 1980 gctcctccac cctataatct ttttatcacc tcccctcctc acacctggtc cggcttacag 2040 tttccttccg tgactagccc tcccccacct gcccagcaat ttactcttaa aaaggtggct 2100 ggagccaaag gcatagtcaa ggttaatgtt ccttttcttt atcccaaatc agaagcattt 2160 aggctctttt tcatcaaata taaaaatcca gcccagttca tggctccttt ggcagcaacc 2220 ctgagacgct ttacagccct agaccctaaa aggtcaaaag gccgtcttat tctcactata 2280 cattttatta cccaatctgc tcctgacatt aaataaaact ccaaaaattg gaatctggcc 2340 ctcaaacccc acaacaggac ttaattaacc tcaaccttca aggtgtacaa taacagaaaa 2400 aagttgcaat tccttgcctt cactgtgaga caaaccccag ccacatctcc agcacacaag 2460 aacttccaaa cacctgaacc acagcggcca ggcattcctc cagaacctcc tcccacagga 2520 gcttgctgca tgtgccaaaa atctggccac tgggccaagg aatgcccaca gcccgggatt 2580 cctcctaagc tgcgtcccat ctgtgtaaga ccccactgaa aatcggacgg ttcaactcac 2640 ctggcagcca ctcccagagc ccctggaact ctggcccaag gctctctgac tgactccttc 2700 ccagatcttc tcggcttagc ggctgaagat tgacactgcc cgatcgcctc ggaagccccc 2760 tagaccatca cggacgctga gcttcgggta attctcacag tggaaggtaa gcctgtcccc 2820 ttcttaatca atacagaggc tacccactcc acattacctt cttttcaagg gcctgtttcc 2880 cttgcctcca taactgttgt gggtattgac agccaggctt ctaaacctct taaaactccc 2940 cgactctggt gccaacttag acaatactct tttaagcact cctttttagt tatccccacc 3000 tgcccagttc ccttattagg ctgagacact ttaactaaat tatctgcttc cctgactatt 3060 cctggactac agctatatct cattgccacc cttcttccca atccaaagcc tcctttgcat 3120 cctcctcttg tatcccccca ccttaaccca caagtataag atacctctac tccctccttg 3180 gcgaccgatc atgcacccct taccatctca ttaaaaccta atcaccctta ccccactcaa 3240 cgccaatatc ccatcccgca gcatgcttta aaaagattaa agcctcttat cactcgcctg 3300 ctacagcatg gccttttaaa gcctataaac tctccttaca attccccgat tttacctgtc 3360 ctaaaaccag ataagcctta caagttagtt caggatctgc gccttagcaa ccaaattgtt 3420 ttgcctatcc accctgtggt gcccaacccg tacactcttt tgtcctcaat accttcctcc 3480 acaactcact attccgtgct tgatcttaaa gatgcttttt tcactattcc cctgcacccc 3540 ttgtcccagc ctctctttgc tttcacttag actgaccctg acacccatcg agctcagcaa 3600 attacctagg ctattcggcc gcaaagcttc acagacagcc cccattactt caatcaagcc 3660 caaatttctt cctcatctgt tacctatctt ggcataattc tcaaaaaaac acacgtgctc 3720 tccctgccaa ttgtgtccaa ctgatctctc aaaccccagc accttctaca aaacaacaac 3780 tcctttcttt cctaggcatg gttagcgcgg tcagaattct tacacaagag ccaggaccac 3840 accctgtagc ctttctgtcc aaacttgacc ttactgtttt agcctagacc tcaggtctgt 3900 gtgcagcggc tgccgctgct ttaatacttt tagaggccct caaaatcaca aactatgctc 3960 aactcactct ctatagttct cataacttcc aaaatctatt ttcttcctca tacctgatgc 4020 atatactttc tgctccgcag ctccttcagc tgtactcact ctttgttgag tctcccacaa 4080 ttactgttgt tcctggccca gacttcaatc cggcctccca cattattcct gataccacac 4140 ctgaccccca tgactgtatc tctctgatcc acctgacatt caccccattt ccccaagttt 4200 ccttctttcc tgttcctcac cctgatcacg cttgatttat tgatggtggt tccaccaggc 4260 cgaatcgcca cacaccagaa aaggcaggtt atactatagt actagccact agcccgtctc 4320 ttagaacctc tcatttcctt tccatcgtgg aaatctatcc tcaaagaaat aacttatcag 4380 tgttccatct gctattctac tactcctcag ggattattca ggccccctcc cttccctaca 4440 catcaagctc aaggatttgc ccccacccag gactggcaaa ttagctttac tcaacatgcc 4500 ctgagtcaga taactaaaat acctcttagt ctagatagat actttcactg gataggtaga 4560 ggcctttcct acagggtctg agaaggccac tgcagtcatt tcttccattc tgtcagacat 4620 aattcctcag tttagccttc ccacctcaat acagtctgat aacagacgag cctttattag 4680 tcaaatcagc taagcagttt ttcaggctct tagtattcag tgaaaccttt atatccctta 4740 cggtcctcca tcttcaagaa aagtagaatg gactaaaggt cttttaaaaa cacacctcac 4800 caagctcagc caccaactta aaaaggactg gacaatacct ttaccacttt cccttctcag 4860 aattcaggcc tgtcctcaga atgctacaag gtacagccca tttaagctcc tgtatggacg 4920 ctccttttta ttaggcccca gtctcattcc agacaccaga ccaacttaga ctgcacccca 4980 aaaaacttgt catccctact atcttctgtc tagtcatact cctattcacc gttctcaact 5040 actcatacat gccctgctct tgtttacact gccggtttac actgtttctc caagccatca 5100 cagctaatat ctcctggtgc tatccccaaa ctgccactct taactcttga agtaaataaa 5160 taatctttgc tggcaggaat atgctgaatc tccttaggca ctctctaatc agatatcctg 5220 agtcgtccca attcttagac cttttatacc tgtttttctc cttctgttat tccatttagt 5280 ttctcaattc atcccaaacc gtatctaggc catcaccaat cattctataa gacaaatgtt 5340 tcttctaaca tccccacaat atcacccctt accacaagac ctcccttcag cttaatctct 5400 cccactctag gttcccatgc cgcccctaat cccgcttgaa gcagccctga gaaacatctc 5460 ccattctctc tccataccac cccccaaaat tttcgccgcc ccaacacttc aacactattt 5520 tgttctattt ttcttattaa tataagaagg caggaatgtc aggcctctga gcccaagcca 5580 agccatcccc tgtgactggc acgtatatgt ccagatggcc tgaagtaact gaagaatcac 5640 aaaagaagtg aatatgccct gccccacctt aactgatgac attccaccac aaaagaagtg 5700 taaatggccg gtccttgcct taactgatga cattaccttg tgaaagtcct tttcctggtt 5760 catcctggct caaaaagcac ccccactgag caccttgcga cccccactcc tgcccgccag 5820 agaacaaacc ccctttgact gtaattttcc tttacctacc caaatcctat aaaatggccc 5880 cacccttatc tcccttcgct gactctcttt ttggactcag cccgcctgca cccagatgaa 5940 ataaacagcc atgttgctca cacaaagcct gtttggtggt cccttcacac ggacgcgcat 6000 gaaa 6004 <210> 39 <211> 3505 <212> DNA <213> Homo sapiens <400> 39 gtcaggcctc tgagcccaag ccaagccatc acatcccctg tgacttgcac gtatacaccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa tacgccctgc cccaccttaa 120 ctgatgacat tccaccacaa aagaagtgta aatggctggt ccttgcctta actgatgata 180 ttaccttgtg aaaatccttt tcctgcctca tcctggctca aaaagcaccc ccactgaaca 240 ccttgcgacc cccactcctg cccaccagag aacaaacccc ctttgactgt aattttcctt 300 tacctaccca aatcctgtaa aacagcccca cccttatctc ccttccctga ctctcttttc 360 ggactcagcc ccccagcacc caggtgaaat aaacagccat gttgctcaca caaaacctgt 420 ttggtggtct cttcacgcag acacacatga aatttggtgc cgttttttgt tgctcacaca 480 aagcctgttt ggtggtctct tcacaggggc gcgcatgaaa tttggtgccg aaacatctgg 540 ttgtcaaaat aacctcatgt gctggctact acagatattt ctaacctcat tttacaaact 600 taaggaactt agccccagag atgttgatct gtctctgttt tttttttttc attcactgaa 660 caaatactta ctgaaaacct actaagtgcc gtatgttgcc ctaagaattg tagggtgaca 720 aaccatccca gcttgcccag aactagggag attcctggga tgcagatttt tcgtgctaaa 780 acgggactgt cctgagcaaa ctgggatggt tgatcagctt aactcaatct ggccacccta 840 acagcacatc acagttcaag tcacaaaata aaccatacca gatggagagc tctgtctctc 900 tctctctttc attatttttg cctcacttgg gacttttatt tctagaccct actcccagca 960 ttagactaaa agttctcctt aatgttgcca gtgatcaccc aagcacgaaa aatactttgc 1020 tgcccactta tctgcaaaat ttgacattct gaccacctga tactctcttt ggcctttact 1080 ctttcccttg cttttctctc tctttcataa tgcccaacat cttcccatct aaactttcat 1140 cattaagtgc atggcaccca aatgtatacc catagctgca atgtgatggc tttgacatgt 1200 ggatgtgtat gactaaaagg tatctcctta actcctggct atcccaagta ttcaaataaa 1260 ctaaatctca acaaaaatgt tgttttctcc acccccaatt cttcctcagc ctctgctcct 1320 tcaccttata atccttctac cacctcccct cctcacaccc ggtctggctt acagtttagt 1380 tccgcgacta gctcttcccc acctgcccaa caatttcctc ttagagaggt ggctggagct 1440 gaaggcacag tcagggcaca tgtacctttt tctctatcag acctctctca gatcagtcaa 1500 tgtttaggct ctttctcatc agaccccact aaatatatac aggaattcca atatctaact 1560 ctgtcctaca acttaacctg gagtgactta aatgtcatcc tgacgtctac cctctcctca 1620 gatgcacggg aaagaatttt ttctctggcc caatctcatg ctgataactg ctggcttcat 1680 gagccagacc tccaggaagg cattagagca gttccccgag aggatcccca atggaactac 1740 caggcaaatt ccccaggtat agctaggcga tattacatgt tttcctgcct agtcgtaggg 1800 cttaaaaaag cagcttacaa agctgttaat tgtgacaaac ttaaagaaac tacccaaggt 1860 aaagatgaaa acccagcccg gttcatggcc cgcttagcgg caacccttag acgctttacc 1920 gccctagacc cagaggggcc agaaggccgc cttattctta acatgcattt tatcacccaa 1980 tccactcctg acattaggaa aaaacttcaa aaactagaat ctggccctca aaccccacaa 2040 caggaattaa tcaacctcac cttcaaggtg tacaataata gagaggaagc agccagacgg 2100 caacgcgttt ctgagttaca attacttgcc tctgctgtga gagaaaaccc agccacacct 2160 cctgcatatg agaacttcaa aatgcctaag ccgcagcagt caagcattcc tacaagactt 2220 cctccaacag gatcttgctt caagtgccag aaatctggcc actgggccaa ggaatgcccg 2280 tagcctggga ttcctcccaa gccatgtccc atctgtgcag ggacccactg gaaatcagac 2340 tgcccagctc acctggcagc cattcctaga gcccctaaag ctctagccca aggctctctg 2400 attccttccc agatcttctt ggcttagcag ctgaagactg acactgcccg attgcctcgg 2460 aagcacccta caccatcaag gacaccgagc ttcaggtaac tctcacagtg gaaggtaagc 2520 ccatcccctt cttaatatgg aggctaccca ctccacatta ccttcttttc aagggcctgt 2580 ttcccttgcc tccataactg ttgtgggtat tgatggccag gcttctaaac ctcttaaaac 2640 tccccaactc tggtgccaac ttagacaata atcttttaag cactcctttt tagttatccc 2700 catctgccca gttcccttat tagtctgaga cactttaact aaattatctg cttccctgac 2760 tattcctgga ctacagctgt atctcattgc tgcccttctt cccaatccag tctcctttgc 2820 gtcctcctct tctatccccc caccttaacc cacaagtata agatacctct actccctcct 2880 tggcgaccga tcatgcaccc cttaccatct cattaatacc taatcaccct tacctcactc 2940 aatgccaata tcccatcccc cagcacgctt taaaaagatt aaagtctgtt atcacttgcc 3000 tgctacagca tggcctttta aaccctataa actctcctta caattccccc attttacctg 3060 tcctaaaacc agacaagcct tacaagttag ttcaggatct gcaccttatc aaccaaattg 3120 ttttgcctct ccaccccgtg gtgcccaacc cgtacactct tttgtcctca ataccttcct 3180 ccacaactca ctattccatg cttgatctta aagatgattt tttcactatt cccctgcacc 3240 cctcatccca gcctctcttt gctttcactt agactgaccc tgagacccat taggctcagc 3300 aaattaccta ggctgtactg ccgcaaggct tcacagacag cccccattac ttcagtcaag 3360 cccaaatttt atcctcacct gttacctatc tcggcataat tctcataaaa acatacgtgc 3420 tttccctgct gatcatgtcc gattaatctc ccaaacctca atcccttaca aaacaacaac 3480 tcctttcctt cctaggcata gttag 3505 <210> 40 <211> 7232 <212> DNA <213> Homo sapiens <400> 40 gacaggcctc tgagcccaag ccaagccatc acatcccctg tgacttgcat gtatatgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aaggccctgc cctgccttaa 120 ctgatgacat tccaccattg tgatttgttc ctgccccacc ttaactgagt gactaaccct 180 gtgaatttcc ttctcctggc tcagaagctc ccccactgag caccttgtga cccccgcccc 240 tgcccaccag aaaacaaccc cctttgactg taattttcca ttaccttccc aaaccctata 300 aaatggcccc acccctatct cccttcgctg actctctttt cggactcagc ccacctgcac 360 ccaggtgaaa taaacagcct tgttgctcac acaaagcctg tttggtggtc tcttcacacg 420 gacgcgcatg aaatttggtg ccatgactcg gatcggggga cctcccttgg gagatcaatc 480 ccctgtcctc ctgctctttg ctccatgaaa aagatccacc tatgacctcg agtcctcaga 540 cccaccagcc taaggaacat ctcaccaatt ttaaattggg taagcagcct cttcttactc 600 tcttctccaa gctctctcac tgtccctcaa ccactttctc ctttccactc ttcaatctct 660 cccttctctt aatttcaatt cctttcattt tctgggagag acaaaggaga catatttaat 720 ccatggaccc aaaactccgg cgctggtcat agactgggaa gacagtcttc ccttggtgtt 780 taatcattgc agggatgcct ctctgattaa acacacaggt ttcaagggtg tcagaccaca 840 cagggacgcc tgccttggtc cttcaccctt agcggcaagt cccgtttttc tggggaaggg 900 gcaagtacct caaccccttc tctccttgtc tctactcctt ctctgctttt ctgggagagg 960 ggcaagtacc cctcaacccc ctctccttca cccttagcgg caagtcccac ttttctatgg 1020 ggcaagaacc cccaatccct tatttccatg ccccaacctc ttatctctgc accacaatcc 1080 cttatttctg tgccccaacc tcttatctct gtgccccaat ccctaatttc tgcaccccga 1140 cctcttatct ctgttcccca tcccttattt ctgcacccca acctcgtatc tctgtgcccc 1200 aatcccttac ttctgcaccc caacctctta tatctctgca ctacaatccc ttatttccat 1260 gccccaacct cttatctctg caccccaatc ccttatttct gtgccctgac cccttatttc 1320 catgccccga ccccttattt ccgtgcccca atcccttatt tctgcacccc atcctcttat 1380 ctctgtgccc caatcgctta tttctgtgcc ccaacctcgt atctctgcac cccaatccct 1440 tatttccgca cactgacctc ttatctctgt gccccaatcc cttatttcca tgccccaacc 1500 ccttctgtgc ttttctggag ggcaagaacc ccccacccct tctctgtgtc tctactcttt 1560 tctctgggct tgcctccttc actatgggta agcttccacc ttccattcct ccttcttctc 1620 ccttagcctg tgttctcaaa aacttaaaac ctgttcaact cacacctgac ctaaaaccta 1680 aatgccttat tttcttctgc aatgccgctt gaccccaata caaactcgac agtagttcca 1740 aatagccaga aaacagcaat ttcaattttt ccatcctaca agatctgaat aattcttgta 1800 aaataggcaa atggtctgag atgcctgatg tccaggcatt cttttacaca tcagtccctt 1860 cctagtctct gtgcccagtg caactcatcc caaatcttcc ttctttcccc cctgcctgtc 1920 ccctcagtcc caaccccaag cgtcactgag tctttctaat attccttttc tacaaaccta 1980 tctgacctct cccctcctcg ccaggctgag ctaggtccca attcttccac cctataatct 2040 ttttatcacc tcccctcctc acaactggtc tggcttacag tttcgttccg tgactagccc 2100 tcccccacct gcccagcaat ttactcttaa aaaggtggct ggagccaaag gcatagtcag 2160 ggttaatgct cctttttctt tatcccaaat cagaagcgtt taggctcttt ttcatcaaat 2220 ataaaaatcc agcccagttc atggctcatt tggcagcaac cctgagacac tttacaaccc 2280 taaaatgtca aaaggccgtc ttattctcaa tatacatttt attaaccaat ctgctcccga 2340 aattaaataa aactccaaaa attggaatct ggccctcaaa ccccacaaca agacttaatt 2400 aacctcacct tcaaggtgtg caataacaga aaatagttgc aattccttgc ctccactgtg 2460 agacaaaccc cagccacatc tccagcacac aagaacttcc aaacgcctga actgcagcag 2520 ccaggcgttc ctccagaacc tcctccccca ggagcttgct acaagtgcca gaaatctgac 2580 caccaggcca aggaatgcct gcagcccagg attcctccta agccgtgtcc catctgtgcg 2640 ggaccccact ggaaatcgga ctgttcagct cacctggcag ccactcccag agcccctgga 2700 actctggccc aaggctctct gactgactcc ttttgggctt agcggctgaa gactgacgct 2760 gcctgatcac ctcggaagcc ccatagacca tcacagacgc cgagctttgg ataactctca 2820 cagtggaagg taagtccgtc cccttcttaa tcaatacgga ggctacccac tccacattac 2880 cttcttttca aggacctgtt tcccttgcct ccataactgt tgtgggtatt gacagccagg 2940 cttctaaacc tcttaaaact ccccaactct ggtgccaact tagacaatac tcttttatgc 3000 accctttttt agttatcccc acctgcccag ttcccttatt aggccgagat attttaacca 3060 aattatctgc ttccctgact attcctggac tatagccgca tctcattgct gcccttcttc 3120 ccaatccaaa gcctcctttg cgtccttctc ttgtattccc ccaccttaac ccacaagtat 3180 aagatacctc tactccctcc ttggtgacca atcatgcgcc ccttaccatc tcattaaaac 3240 ctaatcaccc ttaccccact caatgccaat atcccatccc agagcacgct ttaaaaggat 3300 taaagcctgt tatcactcac ctgctacagc atgggcttct aaaacctata aactctcctt 3360 accattcccc cattttacct gtcctaaaac cagacaagcc ttacaagtta gttcagaatc 3420 tgtgccttat caaccaaatt gttttgccta tccaacccat ggtgccaaac ccatatactc 3480 tcctatcctc aatacctccc tctactaccc attattctgt tctggatctc aaacatgctt 3540 tctttactat tcctttgcac ccttcacccc agcctctctt tgccttcact tagtttgacc 3600 ctgacaccca ttaggctcag caaattacct gggctgcact gccgcaaggc ttcacagaca 3660 gcccccatta cttcagccaa gcccaaattt catcctcatc tgttacctat cttggcataa 3720 ttctcataaa aacacacgtg ctctccctgc tgatcatgtc cgattaatct cccaaacctc 3780 aatcccttac aaaacaacaa ctcctttcct tcctaggcat ggttagtgtg gtcagaattc 3840 ttacacaaga gccaggacca caccgtgtag cctttctgtc caaacaactt gaccttactg 3900 ttttagccta gccctcatgt ctgtgtgcag cagctgctgc tgctttaata ctgttagagg 3960 ccctaaaaat cacaaactat gctcaactca ctctctacat ttctcataac ttccaaaatc 4020 tattttcttc ctcatacctg acacatatac tttctgctcc ctggctcctt cagctgtact 4080 cactatttaa gtcccacaat taccattgtt cctggcccgg acttcaatct ggcctctcac 4140 attattcctg ataccacacc tgacccccat gactgtatct ctctgatcca cctgatattc 4200 accccatttc cccatatttc cttctttcct gttcctcacc ctgatcatgc ttgatttatt 4260 gatggcagtt ccaccaggcc taatcgccac acaccagcaa aggcaggcta tgctatagta 4320 caagccacta gcccacctct cagaacctct catttccttt ccatcatgga aatctatcct 4380 cgaggaaata acttctcagt gttccatctg ctattctact actacacagg gattattcag 4440 gccccctccc ttccctacac ataaagctcg aggatttgcc cccacccagg actggcaaat 4500 tagctttact caacatgtcc cgagtcagga aactaaaata cctcttagtc taaatagaca 4560 ctttcactga ataagtaaag acctttccta cagggtctaa gaaggccacc acagtcattt 4620 cttccctact gtcagacata attcctcagt ttagccttcc cacctctata cagtctgata 4680 acagaccagc ctttattagt caaatcagcc aagcagtttt tcaggctctt agtattcagt 4740 gaaaccttta tatcccttac ggtactccat cttcaagaaa agtagaacgg actaaaggtc 4800 ttttaaaaac acacctcacc aagctcagcc accaacttaa aaaggactgg acaatacttt 4860 tatcactttc gcttctcaga attcaggcct gtcctcagaa tgctacaagg tacagcccat 4920 ttgagctcct gtatagacgc tccttttttt tttttattta agttttaggg tacatttgca 4980 cattgtgcag gttagttaca tatgtataca tgtgccatgc tggtgcgctg cacccactaa 5040 cttgtcatct agcattaggt atatctcccg atgctatccc tcccccctcc ccccacccca 5100 caacagtccc cagagtgtga tgttcccctt cctgtgtcca tgtgatctca ttgttcaatt 5160 cccacctatg agtgagaata tgtggtgttt cgttttttgt tcttgagata gtttactgag 5220 aatgatgatt tccaatttca tccatgtccc tacaaaggac atgaactcat cattttttat 5280 ggctgcatag tattccatgg tgtatatgtg ccacattttc ttaatccagt ctatcattgt 5340 tggacatttg ggttggttcc aagtctttgc tattgtgaat agtgctgcat gtgtgtgaat 5400 aaacatacgt gtgcatgtgt ctttatagca gcatgattta tagtcctttg ggtatataac 5460 cagtaatggg atggctgggt caaatggtat ttctagttct agatccctga ggaatcgcca 5520 cactgacttc cacaatggtt gaactagttt acagtcccac caacagtgtc aaagtgttcc 5580 tatttctcca catcctctcc agcacctgtt gtttcctgac tttttaatga ttgccattct 5640 aactggtgtg agatggtatc tcattgtgga tttgatttgc atttctctga tggccagtga 5700 tgatgagcat tttttcatgt gtcttttggc tgaataaatg tcttcttttg agaagtgtct 5760 gttcatgtcc ttcgcccact ttttgatggg gttgtttgtt tttttcttgt aaatttgttt 5820 gagttcttta tagattctgg atattagccc tttgtcagat gagtaggttg cgaaaatttt 5880 ctcccatttt gtaggttgcc tgttcactct gatggtagtt tcttttgctg tgcagaagct 5940 ctttagttta attagatccc atttgtcaat tttggctttt gttgccattg cttttggtgt 6000 tttagacatg aagtccttgc ccatgcctat gtcctgaatg gtaatgcctg gctagccata 6060 tgtagaaagc tgaaactgga tcccttcctt acaccttata caaaaatcaa ttcaagatgg 6120 attaaagact taaacgttag acctaaaacc ataaaaaccc tagaagacac tcctttttat 6180 taggccccag tctcattcaa caccagacca acttagactg tccctcaaaa aaacttgtca 6240 tccctactat cttttgtcta gtcatactcc tattcaccat tctcaactac tcatacatgc 6300 cctgctctta tttacactgc tggtttacac tgtttctcca agccatcaca gctgatatct 6360 cctggtgcta tccccaaact gccactctaa actcttgaag taaataaata atctttgctg 6420 gcaggactat gctgaatctc cttaggcact ctctaatcag atgtcctagg tcctcccaat 6480 tcttagacct tttatacctg tttttctcct tctcttattc cagtttttca attcatacaa 6540 aactgtatcc aggccatcac cagtcattct atacgacaaa tgtttcttct gataacccca 6600 caatatcacc ccttaccaca agatcttcct ttagcttaat ctctcccact ctaggtttcc 6660 acaccgcccc taatcctgct tgaagcagcc ctgagaaaca tcgtccattc tctctccata 6720 ccacccccaa aaattttcgc cgccccaaca cttcaacact attttgtttt ctttttctta 6780 ttaatataag aaggcaggaa tgtcaggcct ctgagcccaa gccaaaccat cgcatcccct 6840 gtgacttgca cgtatacgtc cagatggcct gaagtaactg aagaatcaca aaagaagtga 6900 aaaggccccg tcccgcctta actgatgaca ttccaccatt gtgatttgtt cctgccccac 6960 cttaactgag tgactaaacc tgtgaatttc cttctcctgg ctcagaagct cccccactga 7020 gcaccttgtg acccccaccc ctgcccatca gaaaacaacc ccctttgact gtaattttcc 7080 attaccttcc caaatcctat aaaacggccc cagcccatct cccttcactg actctctttt 7140 tggactcagc ctgcctgcac ccaggtgaat aaacagcctt gtggctcaca caaagcctgt 7200 ttggtggtct cttcacatgg acgcgcatga aa 7232 <210> 41 <211> 5673 <212> DNA <213> Homo sapiens <400> 41 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac gtacacatcc 60 agatcgacag ttcctgcctt aactgataac attccaccac aaaagaagtg aaaatggcct 120 gttcctgcct taactgatga cattgtcttg tgaaattcct tctcctggct catcctggct 180 caaaagctcc cccactgagt accttgtgac ccccactcct gcctgccaga gaacaacccc 240 cccttttgct ttacctaccc aaatcctata aaacagctcc acccctatct cccttcactg 300 actctctttt tggactcagc ccacctgcac ccaggtgaaa taaacagctt tattgctcac 360 acaaagcctg ttggtggtct cttcacacgg acgcacatga aatttggtgc cgcgactcag 420 atcaggggac ctcccttggg agatcaatcc cctgtcctcc tgttctttgc tccgtgagaa 480 agatccactt acgacctcag gtcctcagac cgaccagccc aaggaacatc tcaccaattt 540 taaatcgggt aagcagactc ttcttactct cttctccaac ctctctcact gtccctcaac 600 cactttctcc tttccactct tcaatctctt ccttctctta atttcaattc ctttcatttt 660 ctggtagaga caaaggagac acgttttatc cgtggaccca aaactctggc gccagtcatg 720 gactagggaa ggcagccttc ccttggtgtt taatcattgg agggacacct ctctgattat 780 tcgtccaggt ttcagaggtg tcagaccacg cagggacgcc tgccttggtc cttcatcctt 840 agtggcaagt cccgcttttc tggggaaggg gcaagtaccc caaccccttc tctctgtgtc 900 tctacctctt ttccaccttt ctggggggca agaaaccccc aacccctttt ccttcaccct 960 gagcagcaag tcccgctttt ctagaggagg ggcaagtacc ccaacctcat atctctgtgc 1020 ccccatccct tatttccgtg ccccaacctc ttatatcgct gtaccccaat ccattatttc 1080 tgtgccctaa cctcttatat ctctgcaccc caatccctta tttccatgcc ctgaccttgt 1140 atctctgtgc cccgacccct ttcccgcttt tctggagggt aagaaccccc aaaccccttc 1200 cctccatgtc tctactctct cttttctctg ggtttgtctc cttcactatg ggcaaccttc 1260 caccctccat tcctccttct tctcccttag tctgtgttct taagaactta aaacctcttc 1320 aactctcatc taacctaaaa tctaagtgtc ttattttctt ctgcaatgcc gcttgacccc 1380 aatacaaact cgacagtagt tccaaatagc cagaaaacgg cactttcaat ttttccatcc 1440 ttcaagatct aaataattct tgttgtaaaa tgggcaaatg gtctgaggtg cctgacatcc 1500 aggcattctt ttacacatca gtccctctat agtctctgtt cccaatgcaa ctcatcccaa 1560 atcttcctcc tttccctccc acctgtcccc tcagtcccaa ccccaagcat cactgagtct 1620 ttctactctt ccttttctac agacacatct gacctctccc ctcctcgcca ggccgagcta 1680 ggtcccaatt cttcctcagc ctccggtcct ccaccctata atccttttat catctcccct 1740 cctcacaccc ggtccggctt acagtttcat tccgtgacta gccctcacct gcccagcaat 1800 ttactcttaa aaaggtggct gaagctaaag gcatagtcaa ggttaatgct cctttttctt 1860 tatcagacct ctcccaaatc agtgagcatt tagactcttt catcaaatat gaaaaaccca 1920 gcccagttca tgactcgttt ggcagcaacc ctgagacact ttacagccct agaccctaaa 1980 aggtcaaaag gccgtcttat tctcaaaata cattttatta cccaatctgc tcccgacatt 2040 aaataaaact ccaaaaatta aattctggcc ctcaaacccc acaacaggat ttaatcaacc 2100 tcgccttcaa ggtgtacaat aatagaaaaa agttgcaatt ccttgcctcc actgtgagac 2160 aaaccccagc cacatctcca gcacacaaga acttccaaat gcctgaacca cagcgggcag 2220 gcgttcctcc agaacctcct cccccaggag cttgctacaa gtgccagaaa tctggccacc 2280 aggccaagga atgcctgcag cccaggattc ctcctaagcc acgtcccatc tgtacggaac 2340 cccactggaa atcggactgt ccaactcacc cggcagccac tcccagagcc cctggaactc 2400 tggcccaagg ctctcagact ccttcccaga tcttcttggc ttagcggctg aagactgacg 2460 ctgcccaatc gcctcggaag ccccctagac catcatggat gccgagcttc gggtaactct 2520 aacagtgaag gataagtctg tccccatctt aatcaatacc aaggctactc actccacatt 2580 accttctttt caagggcctg tttcccttgc ctccataact gttgtgggta ttgatggcca 2640 ggcttctaaa cctcttaaaa gtccccaact ctggtgccaa attagacaat actcttttaa 2700 gcactccttt taattatccc cacctgccca gttccctatt aggccgagac actttaacta 2760 aattatctgc ttccctgact attcctggat tacagctaca tctcattgct gcccttcttc 2820 ccaatccaaa gcctcctttg cgtgctcctc ttgtattccc ccaccttaac ccacaagtat 2880 aagatacctc tactccctcc ttggcaaccg atcatgcacc ccttaccatc tcattaaaac 2940 ctaatcaccc ttactccaat caatgccaat atcccatccc acagcatgct ttgaaaggat 3000 taaagcctgt tatcacttgc ctgctacagc atggccattt aaagcctata aactctcctt 3060 acaattcccc cattttacct gtcctaaaac cagacaagcc ttacaagtta gttcaggatc 3120 tgcgccttat caaccaaatt gttttgccta tccaccccgt ggttccaaat ccatatactc 3180 tcctatcctc aatacctccc tccacaatcc attattctgt tctggatctc aaacatgctt 3240 tctttactat tcctttccac ccttcatccc agcctctctt ggctttcact tggactgacc 3300 ctgacaccca ctaggctcag caaattacct aggctgtact gccgcaaggc ttcacagaca 3360 gcccccatta cttcagtcaa gcccaaattt catcctcatc tgttacctat ctcggcataa 3420 tctcataaaa acacacgtgc gttccctgct gatcgtgtcc gattaatctc ccaaacctca 3480 atcccttaca aaacaacaac tcctttcctt cctaggcatg gttagtgcgg tcagaattct 3540 tacacaagag ccaggaccgc accctgtagc ctttctgtcc aaacaacttg accttactgt 3600 tttagcctag gcatcatgtc tccgtgcagc ggctgctgcc accctaatac ttttagaggc 3660 cgtcaaaatc acaaactatg ctcaacttac tctctacatt tctcataact tccaaaatct 3720 attttcttcc tcatatctga cgcatatact ttctgctccc cggctccttc agctgtactc 3780 actctttgtt aagtcccaca attaccattg ttcctggccc ggacttcaat ccagcctccc 3840 acattattcc tgataccaca cccgacctcc atgactgtat ctgtctgatc ctcctgacat 3900 tcaccccatt tccccatatt tccttctttc ctgttcctca ccctgatcac gcttgattta 3960 ttgatggcag ttccactagg cctaatcgcc acacaccagc aaaggcaggc tatgctatag 4020 tacaagccac tatcccgcct ctttgaacct ctcatttcct ttccatcgtg gaaatctatc 4080 ctcaaggaaa taacttctca gtgttccatc tactattcta ccactcctca gggattattc 4140 aggccccctc ccttccctac acatcaagct tgaggatttg gccccaccca ggactggcaa 4200 attagcttta ctcaacatgc ccggagtcag ataactaaaa tacctgttag tctaggtaga 4260 cactttcact ggataggtag agtcctttcc tacagggtct gagaaggcca ccacagtcat 4320 tttttccctt ctgtcagaca taattcctca gtttagcctt cctacctcaa tacagtctga 4380 taacagacaa gcttttatta gtcaaatcag ccaagcagtt tttcaggctc ctagtattca 4440 gtgaaacctt tatatccctt acggtcctcc atcttcagga aaagtagaac agactaaagg 4500 tcttttaaaa acacacctca ccaagctcag ccaccaactt aaaaaggact ggataatact 4560 tttatgactt tcccttctca gaagtcagac ctgtcctcag aatactacaa ggtacagccc 4620 atttgagctc ctgtatagac gttccttttt attaggcccc agtctcattc cagacaccag 4680 aacttagact gtgcccccca aaaacttgtc atccctacta tcttctgtct agtcatactc 4740 ctattcaccg ttctcaacta ctcatacatg ccctgctatt gtttacactg ccggtttaca 4800 gtttctccaa gccatcacag ctgatatctc ctggtgccat ccccaaactg ccactcttaa 4860 ctcttgaagt aaataaataa tctttgctgg caggactatg ctgatctcct taggcactct 4920 ctaagcagat gtcctgagtc atcccaattc ttagaccttt tatacctgtt tttctccttc 4980 tcttattccg tttagttttt caattcatac aaaactgtta tccaggccat caccaatact 5040 tctaaattac aactattcct tctaacaacc ccacaatatc accccttacc acaaaatctt 5100 ccttcagctt aatctctccc actctaggtt cccacgcccc cccaatccca ctcaaagcag 5160 ccctgagaaa catcgcccat tatctctcca taccatcccc caaaattttt gctgtcccaa 5220 gactttacca ctatttcatt ttatttttct tattaatata agaagacagg aatgtcaggc 5280 ctctgagccc aagctaagcc atcatatccc gtgacctgca cgtacacatc cagatcgcgg 5340 gttcctgcct taactgataa cattccacca taaaagaagt gaaaatggcc tgttcctgcc 5400 ttaactgatg acattgtttt gtgaaattcc ttctcctggc tcatcctggc tcaaaagcgc 5460 ccccactgag tacctgtgcc ccccactcct gcctgccaga gaacaacccc cctttttcct 5520 ttacctaccc aaatcctata aaacggcccc acccctatct cccttcactg actctctttt 5580 tggactcagc ccacctgcac ccaggtgaaa taaacagctt tattgctcac acaaagcctg 5640 tttggtggtc tcttcacacg gacgcgcatg aaa 5673 <210> 42 <211> 7833 <212> DNA <213> Homo sapiens <400> 42 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac atatacaccc 60 agatggcctg aagtaactga agatccacaa aagaagtaaa aatagcctta actgatgaca 120 ttccaccatt gtgatttgtt cctgccccac cctaactgat caatgtactt tgtaatctcc 180 cccaccctta agaaggttct ctgtaattct cctcaccctt gagaatgtac tttgtgagat 240 ccacccctgc ccgcaaaaca ttgctcttaa cttcaccgcc taacccaaaa cctataagaa 300 ctaatgataa tccatctccc ttcactgact ctcttttcgg actcagccca cctgcaccca 360 ggtgaaataa acagctatgt tgctcacaca aagcctgttt ggtggtctct tcacaaggac 420 gcacatgaaa tttggtgccg tgactcggac caggaccgca ccctgtagcc tttctgtcca 480 aacaacttga ccttactgtt ttagcctaac cctcatgtct gcatgcagtg gctgccactg 540 ctttaatact tttagaggcc ctaaaaatca caaactatgc tcaactcact ctctacattt 600 ctcataactt ccaaaatcta ttttcttcct catacctgac gcatatactt tctgctcccc 660 ggctccttca gctgtactca ctctttgtta agtcccacaa ttactattgt tcctggcccg 720 gacttcaatc tggcctccca cattattcct gataccacac ctgaccccca tgactgtatc 780 tctctgatcc acctgatatt caccccattt ccccatattt ccttctctcc gtgtctctac 840 cccttctctg cttttctggg ggaggggcaa gtacccctca atcccttctc cttcaccctt 900 agtggcaagt cctgcttttc tggggaaggg gcaagtaccc caaccccttc tctccttgtc 960 tctacccctt ctctgctttt ctggggaagg ggcaagtacc ccaacccctt ctctccatgt 1020 ctatacccct tctctgattt tctggggcag gggaaagaac ccctcaaccc cttctccttc 1080 acccttagtg gcaagtcccg cttttctggg gaagaggcaa gtaccccaac cccttctctc 1140 cttgtctcta ccccttctct gattttctgg ggcaggggca agaacccctc aactccttct 1200 ccttcaccct cagcggcaag tcccactttt ctgggggagg ggcaagtact ccaacccctt 1260 ctctctgtgt ctctatccct tctctgcttt tctgggggag aggcaagtac cccaacctcg 1320 tatctctgca ccccgatccc ttatttctgc accctgacct cgtatctctg caccccaacc 1380 ccttctctgc ttttctggag ggcaagaaac ccccacccct tctccgtgtc tctactcttt 1440 tctctgggct tgcctccttc acgatgggta agcttccacc ttccattcct ctttcttctc 1500 ccttagcctg tgttcttaag aacttaaaac ctcttcaact ttcacctgac ctaaaaccta 1560 aatgccttat tttcttctgc aatgccgctt gaccccaata caaactcgac agtagtccca 1620 aatagccaga aaactgcact ttgaattttt ccatcctgca agatctaaat aattcttctc 1680 gtaaaatagg caaacggtct gaggtgcctg aagtccaggc attcttttac acatcagtcc 1740 ctctctagtc tctgttccaa tgcaactcat cccaaatctt ccttctttcc ctcctgcctg 1800 tcccctcagt cccaacccca agcgtcgctg agtctttcta atcttccttt tctacagact 1860 cttctgacct ctcccctcct cgccaggccg agctaggtcc caattcttcc tcagcctccg 1920 ctcctccacc ctataatcct tttatcacct cccctcctca cacccagtct ggtttacagt 1980 ttcgttccgt gactagccct cccccacctg cccagcaatt tactcttaaa aaggtggctg 2040 gagctaaagc catagtcaag gttaatgctc ctttttcttt atcccaaatc agatagtgtt 2100 taggctcttt ttcatcaaac ataaaaaacc cagcccagtt catggctcat tcagcagcaa 2160 ccctgagacg ctttacagcc ctagacccta aaaggtcaaa aggccgtctt attctcaata 2220 tacattttat tacccaatct gctcccgaca ttaaataaac tccaaaaatt aaattccggc 2280 cctcaaaccc cacaacagga tttaattaac ctcgccttca aggtgtacaa taatagaaaa 2340 aagttgcaat tccttgcctc cactgtgaga caaaccccag ccacatctcc agcacacaag 2400 aacttccaaa tgcctgaact gcagcagcca ggcgttcctc cagaacctcc tcccccagga 2460 gcttgctaca catgccggaa atctggccac tgggccaagg aatgcccgca gcctgggatt 2520 cctcctaagc cgcgtcccat ctgtgcagga ccccactgaa aattggactg ttcaactcac 2580 ctggcagcca ctcccacagc ccctggaact ctggcccaag gctctctgac tccttcccag 2640 atcttctcgg cttagcggct gaagactgac gctgcccaat cacctcggaa gccccctaga 2700 ccatcacagg tgccgagctt ccagtaactc acagtggaag gtaagtccat ccccttctta 2760 atcaatatgg aagctaccca ctccacatta ccttcttttc aagggcctgt ttcccttgct 2820 tccataactg ttgtgggtat tgacggccag gcttctaaac ctcttaaaac tccccaactc 2880 tggtgccagc tgagacaata ctcttttaag cactcctttt agttatcccc acctgcccag 2940 ttcccttatt aggccgagac actttaacta aattatctgc ttccctgact attccgggat 3000 tacagctaca tctcattgcc acctttcttc ccaatccaaa gccttctttg cgtcctcctc 3060 ttgtattccc cgaccttaac ccacaactat aagatacccc tactccctcc ttggtgaccg 3120 atcatgcacc ccttaccatc tctttaaaac ctaatcaccc ttaccccact caatgccaat 3180 atcccatccc acagcacact ttaaaaggat taaagcctgt tatcactcgc ctgctacagc 3240 ataggcttct aaaacctata aactctcctt acaattcccc aattttacct gtccaaaaac 3300 agaacaagtc ttacagatta gttcaggatc tgcgccttat caaccaaatt gttttgccta 3360 tccaccccgt ggtgccaaac ccatatactc tcctatcctc aatacctccc tctactaccc 3420 attattctgt tctagatctc aaacatgctt tctttttttt tgaaactttt tatttttttt 3480 ggaaactttt tactttgata tgatttattt atttatttat tttttttttt ttattgatca 3540 ttcttgggtg tttctcgcag agggggattt ggcagggcca caggacaata gtggagggaa 3600 ggtcagcaga taaacaagtg aacaaaggtc tctggttttc ctaggcagag gaccctgcgg 3660 ccttccgcag tgtttgtgtc cctgggtact tgagattagg gagtggtgat gactcttaac 3720 gagcatgctg ccttcaagcg tctgtttaac aaagcacatc ttgcaccgcc cttaatccat 3780 ttaaccctga gtggacatag cacatgtttc agagagcaca gggttggggg taaggtcacc 3840 gatcaacagg atcccaaggc agaagaattt ttcttagtac agaacaaaat gaaaagtctc 3900 ccatgtctac ctctttctac acagacacag caaccatccg atttctcaat cttttcccca 3960 cctttccccc ctttctattc cacaaaaccg ccattgtcat cccggcccgt tctcaatgag 4020 ctgttgggta cacctcccag acggggtggt ggccgggcag aggggctcct cacttcccag 4080 taggggcggc cgggcagagg cacccctcac ctcccggacg gggcgactgg ccgggcgggg 4140 ggctgacccc cccatctccc tcccggacgg ggcggctggc caggcagagg ggctcacttc 4200 ccagtagggg tggccgggca gaggcgcccc tcacctcccg gagggggcgg ctggccgggc 4260 ggggggctga tccccccacc tccctcccgg acggggcggc tggccgggcg gggggctgac 4320 ccccccacct ccctcctgga cggggtggct gccgggcgga gacgctcctc acttcccaga 4380 cggggtggct gccgggcgga ggggctcctc acttctcaga cggggcggct gctgggcgga 4440 ggggctcctc acttctcaga cagggcggtt gccaggcaga gggtctcctc acttctcaga 4500 cggggcggcc gggcagagac gctcctcaca tcccggacgg ggcgacaggg cagaggcgct 4560 ccccacatct cagatgatgg gtggccgggc agagacgctc ctcacttcct agatgggatg 4620 gcggcctggc agagacgctc ctcactttcc agactgggca gccaggcaga ggggctcctc 4680 acatcccaga cgatgggcgg ccaggcagag atgctcctca cttcccagac ggggtggcgg 4740 ccgggcagag gctgcaatct cggcactttg ggaggccaag gcaggctgct gggaggtgga 4800 tgttgtagcg agccgagatc atgccactgc actccagcct gggcaccatt gagcactgag 4860 tgaaggagac tccgtctgca atcccggcac ctcgggaggc cgaggctggc ggatcactcg 4920 cggtcaggag ctggagacca gcccggccaa cacaacgaaa ccccgtctcc acccaaaaaa 4980 tacgaaaacc agtcaggcgt ggcggcgcgc gcctgcaatt gcaggcactc agcaggctga 5040 ggcaggagaa tcaggcaggg aggttgcagt gagccgagat ggcagcagta cagtccagct 5100 tcggctctgc atcagaggga gaccgtggaa agaggggagg gggaggggga gagggagagg 5160 gagagggaga gggagaggga gagggagagg gcatgctttc tttactattc ctttgcaccc 5220 ttcatcccag cctctctttg ctttcacttg gactaaccct gacacccatc agtcccagca 5280 gcttacctgg gctgtactgc cgcaaggttt cagggacagc cctcattact tcagccaagc 5340 tctgtctcat gatttagttt ctttccaccc ctccgcttct caccttattc agtatattga 5400 tgaccttctt ctttgtagcc cctcctttga atcttctcaa caagacacac ttctgctcct 5460 tcagcattta ttctccaaag gatagcgggt attcccctcc aaagctcaaa ttttttcccc 5520 atccattacc tacctcggca taattcttca taaaaacaca tgtgctctcc cttctgatca 5580 tgtccgatta atctcccaaa cctcaatccc ttacaaaaca acaactcctt ttcttcctag 5640 gcatggttag tgtggtcaga attcttacac aagagccagg accacaccct gtagcctttc 5700 tgtccaaaca acttgacctt actgttttag cctagccatc atgtctccgt gcagcggctg 5760 ccactgcttt aatactttta gaggccctaa aaatcacgaa ctgtgctcaa ctcactctct 5820 gcatttctca taacttctga aatctacttt cttcctcata cctgatgcat atactttctg 5880 ctccctggct ccttcagctg tactcactct ttgttaagtc ccacaattac cattgttcct 5940 ggcccggact tcaatctggc ctcccacatt attcctgata ccacacctga cccccatgac 6000 tgtatctctc tgatccacct gatattcacc cgatttcccc atatttcctt cttttctgtt 6060 cctcaccctg atcacgcttg atttattgat ggcagttcca ccaggcctaa tcgccacaca 6120 ccagcaaagg caggctatgc tatagtacaa gccactagcc cgcctcttag aacctctcat 6180 ttcctttcca tcgtggaaat ctatcctcaa ggaaataact tctcagtgtt ccatctgcta 6240 ttctactact cctcagggat tattcaggcc ccctcccttc cctacacatc aagcttgaag 6300 atttgccccc acccaggact ggcaaattag ctttactcaa catgccctga atcaggaaac 6360 taaaatacct cttagtctaa ctagacactt tcactgaata agtaaagacc tgtcctacag 6420 ggtctgagaa ggccaccgca gtcatttctt ctcttctgtc agacataatt cctcagttta 6480 gccttcccac ctctatacag tctgataaaa gaccagcctt tattagtcaa atcagccaag 6540 cagtttttca ggctcttagt actcagtgaa acctttatat cccttacggt cctcagtctt 6600 caagaaaagt agaacagact aaaggtcttt taaaaacaca cctcaccaag ctcagccacc 6660 aacttaaaaa ggactggata atacttttac cactttccct tctcagaagt cagacctgtc 6720 ctcagaatgc tacaaggtgc agcccatttg agctcctgta tagacgctcc tttttattag 6780 gccccagtct cattcgacac cagaccaact tagactgtga ccccaaaaaa cttgtcatcc 6840 ctactatctt ctctctagtc atactcctat tcaccgttct caactactca tacatgccct 6900 gctcttgttt acactgctgg tttacactgt ttctccaagc catcacagct gatatctcct 6960 ggtgctatcc ccaaactgcc actctaaact ctggaagtaa ataaataatc tttgctggca 7020 ggactatgct gaatctcctt aggcactctc taatcagatg tcctaggtcc tcccaattct 7080 tagacctttt atacctgttt ttctccttct cttattccat ttagtttctg aattcatcca 7140 aaaccgtatc caggccatca ccaataattc tatatgacaa atgtttcttc taacatcccc 7200 acaatatcac cccttaccac aagatctccc ttcagcttaa tctctcccac tctaggctcc 7260 cacgccaccc ctaatcccgc ttgaagcagc cctgagaaac atcacccatt ctctctccat 7320 accacccccc aaaaattttc accgccctaa cacttcaaca ctattttgtt ttatttttct 7380 tattaatata agaaggcagg aatgtcaggc ctctgagccc aagccaagcc atcgcatccc 7440 ctgtgacttg cacatataca accagatggc ctgaagtaac tgaagatcca caaaagaagt 7500 aaaaatagcc ttaactgatg acattccacc attgtgattt gttcctgccc caccctaact 7560 gatcaatgta ctttgtaatc tcccccaccc ttaagaaggt tctctgtaat tctcctcacc 7620 cttgagaatg tactttgtga gatccacccc tgcccgcaaa acattgctct taacttcact 7680 gcctatccca aaacctataa gaactaatga taatccatct cccttcactg actctctttt 7740 cggactcagc ccacctgcac ccaggtgaaa taaacagcca tgttgctcac acaaagcctg 7800 tttggtggtc tcttcacaag gacgtgcatg aaa 7833 <210> 43 <211> 450 <212> DNA <213> Homo sapiens <400> 43 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac ttatacgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aatgccctgc cccgccttaa 120 ctgatgacat tccaccacaa aagaagtgta aatggccagt ccttgcctta agtgatgaca 180 ttaccttgtg aaagtccttt tcctggctca tcctggctca aaaagctccc ccactgagca 240 ccttgtgacc cccactccca tccgctagag aacaaacctc ctttgactgt aattttcctt 300 tacctaccca aatcttataa aatggcccca cccctatctc ccttctctga ctctcttttc 360 ggactcagcc cacctgcacc caggtggtta aaagctttat tgctcacaca aagcctattt 420 ggtggtctct tcacatggac gcgcatgaaa 450 <210> 44 <211> 389 <212> DNA <213> Homo sapiens <400> 44 gtcaggcctc tgagcccaag ctaagccatc atatccccag tgacctgcat gtatacatcc 60 agatggcctg aagcaagtga agaatcacaa aagaagtgaa aatggccggt tcctgcctta 120 actaatgaca ttaccttgtg aaattccttc tcctggctca gaagctcccc cactgagcac 180 cttatgaccc ccccacccct gcccaccaga gaacaacaac cccctttgac tgtaattttc 240 cactacctac ccaaatccta taaaacggcc ccacccctgt ctcctttccc agactctctt 300 ttcggactca gccagcctgc acccaggtga ttagaaagct gtattgctca cacaaagcct 360 gtttgttggt ctcttcacac ggatgcatg 389 <210> 45 <211> 3720 <212> DNA <213> Homo sapiens <400> 45 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcag gtatctgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa tatgccctgc cccaccttaa 120 ctgatgacat tccaccacaa aagaagtata aatggccggt ccttgcctta agtgatgaca 180 ctaccttgtg aaagtccttt tcctggctca tcctggctca gaagctcccc cactgagcac 240 cttgtgaccc ccacccctgc ccaccagaga acaaccccct ttgactgtaa ttttccatta 300 ccttcccaaa tcctataaaa cagccccacc cctatctccc ttggctgact ctcttttcgg 360 actcagccca cctgcaccca ggtgaaataa acagccatgt tgctcacaca aagcctgttt 420 ggtggtctct tcacacggac gcgcatgaaa tttggtgccg tgactcggat cgggggacct 480 cccttgggag atcaatcccc catcctcctg ctctttgctc catgagaaaa atccacctat 540 gaccttaggt cctcagaccg accagcccaa gaaacatctc accaatttca aatccggtaa 600 gcggcctctt tttactctct tctccaacct ccctcactat ccctcaacct ctttctcctt 660 tcaatcttgg caccacactt caatctctcc cttctcttaa tttcaattcc tttcattttc 720 tggtagagac aaaggagaca cgttttatcc gtggacccaa aactccggcg ctggccacag 780 actgggaagg cagccttccc ttggtgttta atcattgcag ggacacctct ctgattattc 840 actcacgttt caagggtgtc agaccacgca gggacgcctg ccttggtcct tcacccttag 900 cggcaagtcc cgcttttctg gggaaggggc aagtacccca accccttctc tccttgtctc 960 taccccttct ctgctcttct gggggagggg caagtacccc tcaacccctt ctccttcatc 1020 cttagtggca agtcccgctt tcctggggca ggggcaagta cccctcaacc ccttctcctt 1080 cacccttagc ggcaagtccc gctttcctag ggggcaaaaa acccccaatc gcttatttct 1140 gcaccctgac ctcttatctc tgtgccctaa tcccttattt ccgtgcccca accccttctc 1200 tgcttttctg gagggcaaga acccccccac cccttctcca tgtctctact cttttctctg 1260 ggcttgcctc cttcactatg ggcaagcttc caccttccat tcctccttct tctcccttag 1320 cctgtgttct caaaaactta aaacctcttc aactcacacc tgacctaaaa tctaaatgac 1380 ttattttctt ctgcaatgcc gcttgacccc aatacaaacc gacagtagtt ccaaatagcc 1440 agaaaatggc actttgaatt tttccatcct gcaagatcta aataattctt gttgtaaaat 1500 aggcaaacgg tctgaggtgc ctgacgtcca ggcattcttt tacacatcag tcccttccta 1560 gtctctgtgc ccagtgcaac tcgtcccaaa tcttccttct ttccctcccg cctgtccccc 1620 cagtcccaac cccaagcgtc gctgagtctt tctaatcttc cttttctaca gacccgtctg 1680 acctctcccc tcctcgccag gccgagctag gcctcaattc ttcctcagcc tctgctcctc 1740 caccctataa tctttttatc gcctcccctc ctcacacctg gtcctgctta cagtttcgtt 1800 ccgtgactag ccctccccca cctgcccagc aatttactct taaaaaggtg gctggagcta 1860 aaggcatagt caaggttaat gctccttttt ctttatccca aatcagatag catttaggct 1920 ctttttcatc aaatataaaa atccagccca gttcatgacg tgtttggcag caaccctgag 1980 acactttaca gccctagacc ctaaaaggtc aaaaggccat cttattctca aaatacattt 2040 tattagccaa tctgctcccg acattaaata aaactccaaa aattagattc cggccctcaa 2100 accccacaac aggatttaat taacctcgcc ttcaaggtgt acaataatag aaaaaagttg 2160 caattccttg cctccactgt gagacaaacc ccagccacat ctccagcaca caagaacttc 2220 caaacgcctg aaccgcagca gccaggcgtt cctccagaac ctcctcccac aggagcttgc 2280 tacacgtgcc ggaaatctgg ccactgggcc aaggaatgcc cgcagcccgg gattcctcct 2340 aagccgcgtc ccatctctct gggaccccac tgaaaatcgg actgttcaac tcacctggca 2400 gccactccca gagcccctgg aactctggcc caaggctctc tgactgactc cttcccagat 2460 cttctcggct tagcggctga agactgacac tgcccgatcg cctcggaagc cccctagacc 2520 atcacagacg ccgagcttcc ggtaactctc acagtgcaag gtaggcccgt ccccttctta 2580 atcaatacgg aggctactca ctccccatta ccttcttttc aagggcctgt ttcccttgcc 2640 tccataactg ttgtgggtat tgacggtcag gcttctaaac ctcttaaaac tccccaactc 2700 tggtgccaac ttagacaata ctcttttaag cactcctttt tagttatccc cacctgccca 2760 gttcccgtat taggctgaga cactttaact aaattatctg cttccctgac tattcctgga 2820 ctacagctat atctcattgc cgcccttctt cccaatccaa agcctccttt gcgtcctcct 2880 cttgtatccc ccgaccttaa cccacaagta taagatacct ctactccctc cttggtgacc 2940 gatcatgcac cccttaccat ctcattaaaa cctaatcacc cttaccccac tcaacgccaa 3000 tatcccgtcc tgcagcatgc tttaaaaaga ttaaagcctg ttatcactca cctgctacag 3060 catggccttt taaagcctat aaactctcct tacaattccc ccgttttacc tgtcagccct 3120 gagaaacatc gcccattctc cctccatacc accccccaaa aattttcacc gctccaacac 3180 ttcaacacta ttttgtttta tttttcttat taatataaga aggcaggaat gtcaggcctc 3240 tgagcccaag ccaagccatc gcatcccctg tgacttgcac atatacgccc agatggcctg 3300 aagtaactga agaatcacaa aagaagtgaa aaggccctgc cctgccttaa ctgatgacat 3360 tccaccattg tgatttgttc ctgccccacc ttaactgagt gattaaccct gtgaatttcc 3420 ttctcctggc tcagaagctg ccccacctta actgagtgat taaccctgcg aatttccttc 3480 tcctggctca gaagctcccc cactgagcac cttgtgaccc ccgcccctgc ccaccagaga 3540 gcaaccccct ttgactgtaa ttttccatta ccttcccaaa tcctataaaa cggccccacc 3600 cctatctccc ttggctgact ctctttgcgg actcagcccg cctgcaccca ggtgaaataa 3660 acagccatgt tgctcacaca aagcctgttt ggtggtctct tcacacagac gcgcatgaaa 3720 <210> 46 <211> 6012 <212> DNA <213> Homo sapiens <400> 46 gtcaggcctc tgagcccaag ccaaccatcc cagcccctgt gacttgcaca tatatgacca 60 gatggcctga agtaactgaa gaatcacaaa agaagtgaat atgccctgcc ccaccttaac 120 tgatgacatt ccaccacaaa agaagtgtaa atggccggtc cttgccttaa ctgatgacat 180 taccttgtga aagtcctttt cctggctcat cctggctcaa aaagcacccc cactgagcac 240 cttgcgaccc ccactcctgc ctgccagaga acaaaccccc tttgactgta attttccttt 300 acctacccaa atcctataaa acggccccac ccttatctcc catcgctgat tctctttttg 360 gactcagccc gcctgcaccc aggtgaaata aacagccatg ttgctcacgc aaagcctgtt 420 tggtggtctc ctcacacgga cgcgcatgaa atttggtgct gtgactcaga atgggggacc 480 tcccttggga gatcaatctc ccgtcctcct gttctttgct ccatgagaaa gatccaccta 540 cgacctcagg tcgtcagaca gaccagccca agaaacatct caaatccggt aagcggcctc 600 tttttactct cttctccaac ctccctcact atccctcaac ctctttctcc tttcaatctt 660 ggtgccacac ttcaatctct cccttctctt aatttcaatt cctttcattt tctggtagag 720 acaaaggaga cacgttttat ccgtggaccc aaaactccgg cgctggtcac ggactgggaa 780 ggcagccttc ccttggtgtt taatcattgc agggacacct ctctgattat tcacccacgt 840 ttcaaaggtg tcagaccacg cagggacgcc tgccttggtc cttcaccctt agtgtcaagt 900 cccacttttc tggggaagga gcaagtaccc caaccccttc tctccttgtc tctacccctt 960 ctctgctttt ctgggggacg gacaagtacc cctcaacccc ttctccttca cccttagtgg 1020 caagtcctgc ttttctacgg ggcaagaacc cccaatccct tatttctgcg ccccaacctc 1080 ttatctctgt gccccaatac cttatttcca tgccccaacc tcttatatct ctgcccccca 1140 atcccttatt tccgcgcccc aacctcttat atctctgcgc cccaatccct tatttccacg 1200 ccccaacctc ttatttctgc accccatccc ttatttctgt gccacaaccc cttttcccac 1260 ttttctggaa ggtaagaacc cccgaacccc ttccctccat ttctctactc tcttttctct 1320 aggcttactt ccttcaccat gggcaacctt ccaccctcca ttcctccttc tactcccttg 1380 gcctgtgttc tcaaaaactt aaaacctctt caactcacac ctgacctaaa acctaaatgc 1440 cttattttct tctgcaatgc tgcttgaccc caatataaac tcgacagtag ttccaaatag 1500 ccagaaaatg gcactttgaa tttttccatc ctgcaaaatc taagtaattc ttgtcgtaaa 1560 ataggcaaat ggtctgaggt gcctgatgtc caggcattct tttacacatc agtcccttcc 1620 tggtctctgt gaccagtgca actggtccca aatcttcctt ctttccctcc cgcctgtctc 1680 ctcagtacca atcccaagcg tcgctgagtc tttctaatct tccttttcta cagacccatc 1740 tgacctctcc cttcctcccc aggctgctcc tcaccaggcc gagctaggtc ccaattcttc 1800 ctcagcctct gctcctccac cctataatct ttttatcacc tcccctcctc acacctggtc 1860 cgactagccc tccccctcct gcccagcaat ttactcttaa aaaggtggct ggagctaaag 1920 gcatagtcaa ggttaatgct cctttccttt ttgtttatcc caaatcagat agtgtttagg 1980 ctctttttca tcaaatataa aaatccagcc cagttcatgg ctcgtttggc agcaaccctg 2040 agacacttta cagccctaga ccctaaaagg tcaaaaggcc gtcttattct caaaatacat 2100 tttattaccc aatctgctcc cgacattaaa taaaactcca aaaattggaa tctggccctc 2160 aaaccccaca acaggactta attaacctca ccttcaaggt gtacaataac agaaaaaaag 2220 ttgcaattcc ttgcctccac tgtgagacaa accccagccg catctccagc acacaagaac 2280 ttccaaatgc ctgaaccgca gcagctaggc attcctccag aacctcctcc cccaggagct 2340 tgctacacgt gctggaaatc tggccaccgg gccaaggaat gcccgtagcc cgggattcct 2400 cctaagccgc gtcccatctg tgtgggaccc cactgaaaat cggactattc aactcacctg 2460 gcagccactc ccagagcccc tggaactctg gcccaaggct ctctgactga ctccttccca 2520 gatcttctcg gcttagcggc tgaagactga cactgcccga tcgcctcgga agccccctag 2580 accatcacag acaccgagct tcgggtaact ctcacagtgg aaggtaagcc tgtccccttc 2640 ttaatcaata cggaggctcc ccactccaca ttaccttctt ttcaagggcc tgtttccctt 2700 gcctccataa ctgttgtggg tattgacggc caggcttctg aacctcttaa aactccccaa 2760 ctctggtgcc aacttagaca atactctttt aagcactcct ttttagttat ccccacctgc 2820 ccagttccct tattaggctg agacacttta actaaattat ctgcttccct gactattcct 2880 ggactacagc tatatctcat tgccgccctt cttcccaatc caaagcctcc tttgcgtcct 2940 cctcttgtat ccttccacct taacccacaa gtataagata cctctactcc ctccttggcg 3000 accgatcatg caccccttac catctcatta aaacctaatc acccttacca cactcaatgc 3060 caatatccca tcccgcagca cactttaaaa agattaaagc ctgttatcac tcgcctgcta 3120 ctgcatggcc ttttaaagcc tataaactct ccttacaatt cccccatttt acctgtccta 3180 aaaccagaca agccttacaa gttagttcag gatctgcgcc ttatcaacca aattgttttg 3240 cctatccacc tcgtggtgcc aaacccatat actctcctat cctcaatacc tgcctctaca 3300 acccattatt ctgttctaga tctcaaacat gctttcttta ctactccttt gcacccttaa 3360 tcccagcctc tctttgcttt cacttggact gaccctgaca cccatcaagc tcagcaaatt 3420 acctaggctg tactgctgca aagcttcaca gacagccccc attacttcaa tcaagcccaa 3480 atttcttcct catctgttac ttatctcagc ataattctca taaaaacaca cgtactctcc 3540 ctgccaattg tgtccgactg atctctcaaa ccctaaccac ttctacaaaa caacaactcc 3600 tttccttcct gggcatggtt ggatactttc gcctttggat acctggtttt gccatcctaa 3660 caaaaccatt atataaactc acaaaaggaa acctagctga ccccatagat cctaaatcct 3720 ttccccactc ctctttccat tccttgaaga cagctttaga aactgccccc accctagctc 3780 tccctgactc atcccgaccc ttttcattac acacagccga agtgcagggc tgtgcagtcg 3840 gaattcttag ataaggacaa cgatcgcgtc ctgtagcctt tttgtccaaa caacttgacc 3900 ttattgtttt aggctggcca tcatgtctct gtgcagccgc tgctgctgcc ctaatacttt 3960 tagaggccct cataatcaca aactatgctc aactcactct ctacagttct cataacttcc 4020 aaaatctatt ttcttcctca tacctgatgc atatactttc tgcttcccgg ctccttcagc 4080 tatactcact ctttgttgag tctcccacaa ttactgttgt tcctggccca gacttcaatc 4140 cggcctcgca cattattcct gataccacac ctgaccccca tgactgtatc tctctgatcc 4200 acctgacatt caccccattt ccccaaattt ccttcttccc tgttcctcac cctgatcacg 4260 cttgatttat tgatggctgt tccaccaggc ctaatcgcca cacaccagaa aggcaggtta 4320 tgctatagta caagccacta gcccacctct taaaacctct catttccttt ccatcgtgga 4380 aatctatcct ccaggaaata acttctcagt gttccatctg ctattctact actcctcagg 4440 gattattcag gccccatccc ttccctacac atcaagctcg aggactggca aattagcttt 4500 actcaacatg cccaagtcag gaaactaaaa tacctcttag tctaaataga cactttcact 4560 gaataagtaa aggcctttcc tacagggtct gagaaggcca ccgcagtcat ttcttccctt 4620 ctgtcagaca taattcctca gtttagcctt cccacctcaa tacagtctga taacagatga 4680 gcctttatta gtcaaatcag gcaagcagtt tttcaggctc ttagtattca gtgaaacctt 4740 tatatccctt acggtcctcc atcttcaaga aaagtagaat ggactaaagg tcttttaaat 4800 acacacctca ccaagttcac caacttaaaa aggactggac aatactttta ctacatttcc 4860 ttctcagaat tcaggcctgt cctcggaatg ctacagggta cagcccattt aagctcctgt 4920 atagacgctc ctttttatta ggccccagtc tcattccaga caccagacca acttagactg 4980 tgtcccaaaa aaacttgtca tccctatctt ctgtctagtc atactcctat tcaccgttct 5040 caactactca tacatgccct gctcttgttt agccggttta cactgttttt ccaagccatc 5100 acagctgata tctcctggtg ctatccccaa actgccactc ttaactcttg aagtaaataa 5160 ataatctttg ctggcaggac tatgccgaat ctccttaagc actctctaat cagataatcc 5220 tgagtcgtcc caattcttag aacttttata cctgtttttc tccttctgtt attccattta 5280 gtttttcaat tcatacaaaa ccgtatccag gccatcacca atcattctat atgacaaatg 5340 ttccttctaa catccccaca atatcacccc ttaccacaag atctcccttc agcttaatct 5400 ctcccactct aggttcccac gccgccccta atcccgcttg aagcagccct gagaaacatc 5460 gcccattctc tctccatacc accccccaaa aattttcgcc actccgacac ttcaacacta 5520 ttttgtttta tttttcttat taatataaga aggcaggaat gtcaggcctc tgagcccaag 5580 ccaagccatc ccatcccctg tgacttgcac atatatgacc aaatggcctg aagtaactga 5640 agaatcacaa aagaagtgaa tatgctctgc cccacattaa ctgatgacat tccaccacaa 5700 aagaagtgta aatggccggt ccttgcctta actgatgaca ttaccttgtg aaagtccttt 5760 tcctggctca tcctggctca aaaagcaccc ccactgagca ccttgtgacc cccactcctg 5820 cccgccagag aacaaacccc ctttgactgt aattttcctt tacctaccca aatcctataa 5880 aacggcccca cccttatctc ccatcactga ttctcttttt ggactcagcc cgcctgcacc 5940 caggtgaaat aaacagccat gttgctcaca caaagcctgt ttggtggtct cttcacacag 6000 acgcgcatga aa 6012 <210> 47 <211> 238 <212> DNA <213> Homo sapiens <400> 47 tacagttgat agctagtcag acacgagcag gataggagag ggctccctgc cctcaccacc 60 aggaatgttg atggtggtga cggtcaggtg gttgttaact gtctctgtaa agtaataatt 120 ggttgcagcc agtgccaggg aagggcagtc ttccagtaga tagaaaacac ctaaaactgg 180 tgatcagcag cttcctgata agacctcagg agttgggcaa gtgggctcag gtgagcac 238 <210> 48 <211> 2205 <212> DNA <213> Homo sapiens <400> 48 tgaggtcaga attcttacac aagagccagg accgcaccct gtagcctttc tgtgcaaaca 60 acttgacctt actgttttag cctagccctc atgtctgtgt gcagcagctg ccgctgcttt 120 aatactttta gaggccctca aaatcacaaa ctatgctcaa ctcactctct gcagttctca 180 taacttccaa aatctatttt cttcctcata cctgatgcat atactttctg ctccccggct 240 ccttcagctg tactcactct ttgttgagtc tcccacaatt accgttgttc ctggcccaga 300 cttcaatccg gcctgccaca ttgttcctga taccacacct gacccccatg actgtatctc 360 tctgatccac ctgatattca ccccatttcc ccaaatttcc ttctttcctg ttcctcaccc 420 tgatcacgct tgatttattg atggcggttc caccaggcct aatcgccaca caccaccagc 480 aaaggcaggt tatactatag tacaagccac tagcccgcct cttagaacct ctcatttcct 540 ttccattgtg gaaatttatc ctcaaggaaa taacttctca gtgttccatc tgctattcta 600 ctactcctca gggataattc aggccccctc cctttcccac acatcaagct cgaggatttg 660 ccccacccag gactggcaaa ttagctttac tcaacatgcc ctgagtcaga taactaaaat 720 acctcttagt ctaggtagat actttcactg gataggtaga ggcctttcct acagggtctg 780 agaaggccac cgcagtcatt tcttcccttc tgtcagacat aattcctcag tttagccttc 840 ccacctcaat acagtctgat aacagaaggg cctttattag tcaaaacagc caagcagttt 900 ttcaggctct tagtattcag tgaaaccttt atatccctta tggtcctccg tcttcaagaa 960 aagtagaatg gactaaaggt cttttaaaaa cacacctcac caagctcagc caccaactta 1020 aaaaggactg gacaatactt ttaccacttt cccttctcag aattcaggcc tgtcctcgga 1080 atgctacagg gtacagccca ttggagctcc tgtatagatg ctccttttta ttaggccccg 1140 gtctcattcc agacaccaga ccaacttaga ctgtgcccct aaaaaacttg tcttccctgc 1200 tatcttctgt ctagtcatac tcctattcac cgttcctaac tactcataca tgccctgctc 1260 ttgtttacac tgctggttta cactgttttt ccaagccatc acagctgata tctcctggtg 1320 ctatccccaa actgccactc ttaactcttg aagtaaataa ataatctttg ctggcaggac 1380 tatgctgaat ctccttaggc actctctaat cagatatcct gagtcgtccc aattcttaag 1440 actttttata cctgtttttc tccttctgtt attccattta gtttctcaat tcatccaaaa 1500 ccgtatctag gccatcagca atcattctat aggacaaatg tttcttctaa catccccaca 1560 atatcacccc ttaccacaag acctcccctc agcttaatct ctcccactct aggttcccac 1620 gctgccccta atcccgcttg aagcagccct gagaaacatc gcccattctc tctccatacc 1680 acgccccaaa aatttttgcc gccccaaaac ctcaacacta ttttattttt cttattaata 1740 taagaaggca ggaatgtcag gcctctgagc ccaagccaag ccatcacatc ccctgtgact 1800 tgcatgtata tgcccagatg gcctgaagta actaaagaat cacaaaagaa gtgaatgtga 1860 cctgccccac cttaactgat gacattccac cacaaaagaa gtgtaaatgg ccggtccttg 1920 cctcaagaga tgacattacc ttgggaaagt ccttttcctg gctcatcctg gctcaaaaag 1980 cacccccact gagcaccttg caacccccac tcctgcccgc cagagaacaa accccctttg 2040 actgtaattt tcctttacct acccaaatcc tataaaacgg ccccacccct atctcccttc 2100 gctgactctt tttggactca gcccacctgc acccaggtga aataaacagc catgttgctc 2160 acacaaagcc tgtttgctgg tctcttcaca gatacgcgca tgaaa 2205 <210> 49 <211> 430 <212> DNA <213> Homo sapiens <400> 49 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcat gtatacatcc 60 agatggcctg aagcaagtga agaatcacaa aagaagtgaa aatggctagt tcctgcctaa 120 actgatgaca ttccaccatt gtgatttgtt tctgccccac cttaactgag cgattaacct 180 tgtgaaattc cttctcctgg ctcagaagct cccccactga gcaccttgtg acccccaccc 240 ttgcccacaa gagagcaacc ccctttgact gtaattttcc actacccacc caaatcctat 300 aaaacggccc cacccctatc tcccttcgct gactgttttt ggactcaagc cacctgcacc 360 caggtgaaat aaacagccct gttactcaca caaatcctgt ttggtggtct cttcacacgg 420 atgcgcgtga 430 <210> 50 <211> 371 <212> DNA <213> Homo sapiens <400> 50 gtcaggcctc tgagcccagg ccaggccatc gcatcccctg tgacttgcac gtacacatcc 60 agatggcctg aagtaactga agatccacaa aagaagtaaa aacagcctta actgatgaca 120 ttccaccatt gtgatttgtt cctgccccac cctaactgat caatgtactt tgtaatctcc 180 cccgccctta agaatgtact ttgtgagatc cccgcctgcc caccagagaa caaccccctt 240 tgactgtaat tttccattac cttcccaaat cctatgaaat ggccccaccc ctatctccct 300 tcgctgactc tctttttgga ctcagcccgc ctgcacccag gtgaaataaa cagccatgtt 360 gctcaaaaaa a 371 <210> 51 <211> 5517 <212> DNA <213> Homo sapiens <400> 51 gtcaggcctc tgagcccagg ctaagccatc atgtcccctg tgacctgcat gtacacatcc 60 agacggctgg ttcctgcctt aactgctgac attccaccac aaaagaagtg aaaatgtcct 120 gttcctgcct caactgatga cattgtcttg tgaaattcct tctcctggct catcctggct 180 caaaagctcc cccactgagt aacttgtaac ccccactctg cccgccagag aacaaccccc 240 cctttgactg gattgggtag gatttaccta cccaaatcct ataaaacggc cccaccccta 300 tctcccttcc ctgactctct ttttggaccc agcacacctg cacccagggg aaataaacag 360 ctttattgct cacagaaagc ctgtttggtg gtctcttcac acagacacga gtgaaatttg 420 gtgctgtgac ttggatcggg ggacctccct tgggacatca atcccctgtc ctcctgttct 480 ttgctccgtg agaaagatcc acctacaacc tcaggtcctc agactgacca gcccaagaaa 540 cgtctcacca atttcaagta tggtaagtgg cctcttttta ctctctcctc caacctcact 600 tactatccct caacctcttt ctcctttcaa tcttggcacc acacttcaat ctctcccttc 660 ttttaatttc aattcctttc attttctggt agagacaaag gagacgcgtt ttatccgtgg 720 acccaaaact ccagtgctgg tcacggactg ggaaggcagc cttcccttgg tgtttaatca 780 tttcagggac gcctctctga ttattcaccc atgtttcaga ggtgtcagac cacgcaggga 840 cgcctgtctt ggtccttcac ccttagaggc aagtcccgct tttctagggg aggggaaagt 900 accccaacct catatctctg tgccctgatc ccttatttcc acaccccaac ctcttatatc 960 tctgtgcccc gatcccttat ttccgtgccc ctacctctcc cgcttttctg gagggtaaga 1020 acccccaaac cccttccctc cgtttctcta ctctctcttt tctctgggct tgcctccttc 1080 actgtgggca accttccacc ctccattgct ccttctccct tagcctgtgt tcttaagaac 1140 ttaaaacctc ttcagctctc acctgaccta aactctcagc atcttatttt cttccgcaat 1200 gccacctgac cgcaatacaa actcgacagt agttccaaat agccagaaaa cggcactttc 1260 aatttttcca tcctgcaaga tctaaataat tcttgttgta agatgggtaa atggtctgag 1320 gtgcctgacg tccaggcatt cttttacacg tcggtccctc tctagtctct gttcccaatg 1380 caactcatcc caaatcttcc ttctttccct cccacccgtc ccctcagtcc caaccccaag 1440 ggtcgctgag tctttctaat cttccatttc tacagaccca tctgacctct cccctcctcc 1500 ccaggctgct cctcgccagg ccgagctacg tcccaattct tcctcagcct ctgctcctcc 1560 accctataat ccttttatca cctcccctcc tcacacctgg tccggcttac agtttcgttc 1620 cgtgaccagc cctcccccac ctgcccagca atttactctt aaaaaggtgg ctggagctaa 1680 aggcatagtc aaggttaatg ctcctttttc tttatcccaa atcagatagc gtttaggctc 1740 tttttcatca aatataaaaa tccagcccag ttcatgactt gtttggcagc aaccctgaga 1800 cactttacag ccctagaccc taaaaggtca aaaggccgtc ttattctcaa aatacatttt 1860 attacccaat ctgctcccga cattaaataa aactccaaaa attaaattcc ggcccttaaa 1920 cccctcaaca ggatttaatt aacctcacct tcaaggtgta caataataga aaaaagttgc 1980 aattccttgc ctccactgtg agacaaaccc cagccacatc tccagcacac aagaacttcc 2040 aaacgcctga accacagcgg ccaggccttc ctccagaaca tcctccccca ggagcttgct 2100 acaagtgcca gaaatctggc caccaggcca aggaatgcct gcagcccggg attcctccta 2160 agccacgtcc catctgtgcg ggaccccact ggaaatcgga ctgtccaact cacctggcag 2220 ccactcccag agcccctgga actctggccc aaggctctct gacggcttcc cagatcttct 2280 tggcttagcg gctgaagact gactctgccc gatcacctcg gaagccccct aggccatcac 2340 ggacgccgag cttcgggtaa ctctcacggt ggaagctaag cccgtcccct tcttaatcaa 2400 tacggagcct acccactcca cattaccttc ttttcaaggg cctgtttccc ttgcctccat 2460 aactgttgtg ggtattgacg gccaggcttc taaacctctt aaaactcccc aactctggtt 2520 ccaacttaga caatactctt ctaagcactc cttttagtta tccccacctg cccagttccc 2580 ttattaggcc gagacacttt aactaaatta tctgcttccc tgactattcc tgtattacag 2640 ctacatctca ttgctgccct tcttcccaat ccaaagcctc ctttgcgtcc tcctcttgta 2700 ttctcccacc ttaacccaca agaataagat acctctactc cctccttggc gaccgatcat 2760 gcacccctta ctatctcatt aaaacctaat cacccttacc ccgctcaatg ccaatatccc 2820 atcccacacc atgctttgaa aggattaaag cctgttatca ctcacctgct acagcatggc 2880 cttttaaagc ctataaactc tccttacaat tcccccatta tacctgtcct aaaaccagac 2940 aagccttcca agttagttca ggatctatgc cttatcaacc aaattgtttt gcctatccac 3000 cccatggtgc caaacccata tactctccta tcctcaatac ctccctccac aatccattat 3060 tctgtgctgg atctcaaacc tgctttcttt actattcctt tgcacccatc atcccagcct 3120 ctcttcgctt tcacctggac tgaccctgac acccatcagg ctcaggaaat tacctgggct 3180 gtactgccgc aaagtttcac agacagcccc cattacttca gtcaagccca aatttattcc 3240 ttatctgtta cctatctcag cataattctc ataaaaacac acgtgctctc cctgctgatg 3300 tccaattaat ctcccaaacc tcaatccctt acaaaacaac aactcctttc cttcctaggc 3360 atggtttgtg cggtcagaat tcttacacaa gagccaggac cgcaccctgt agcctttctg 3420 tccaaacaac ttgaccttac tgttttagcc tagccctcat gtctgcgtgc gtggctgctg 3480 ccaccctaat acttttagag gccctaaaaa tcacaaacta tgctcaactt actctctaca 3540 tttctcataa cttccaaaat ctattttctt cctcatacct gacgcatata ctttcggctt 3600 cctggctcct tcagctatac tcactctttg ttaactccca caattaccat tgttcctggc 3660 ccggacttca atctggcctc ccacattatt cctgatacca cacctgacct ccatgactgt 3720 atctctctga tccacctgac attcaccaca tttccccata tttccttctt tcctgttcct 3780 caccctgatc acgcttgatt tattgatggc agttccacca ggcctaatcg ccacacacca 3840 gcaaaggcag gctatgctat agtacaagcc actagccccc ctcttagaac ctctcatttt 3900 ctttccatcg tggaaatctg tcctcaagga aataacttct cagtgttcca tctgctattc 3960 tactactcct cagggattat tcaggccccc tcccttcctt acacatcaag ctcgaggatt 4020 tgcccctacc caggactggc aaattagctt tactcaacat gccccgagtc agataactaa 4080 aatacctctt agtctaggta gacactttca ctggataggt acaggccttt cctacagggt 4140 ctgagaaggc caccgcagtc atttcttccc ttctgtcaga cacaattcct cagtttagcc 4200 ttcccacctc aatacagtct gataacagac gagcctttat tagtcaaatc agccaagcag 4260 tttttcaggc tcttagtatt cagtgaaacc tttatatccc ttatggtcct ccgtcttcag 4320 gaaaagtaga atggactaaa ggtcttttaa aaacacacct caccaagctc agtcaccaac 4380 ttaaaaagga ctggacaata cttttaccac tttcacttct cagaactcag gcctgtcctc 4440 ggaatgctac agggtacagc ccatttgagc tccttttttt attaggcccc agtctcattc 4500 cagacaccag accaacttgg actgtgcccc aaaaaacttg tcatccctac tatcttctgt 4560 ctagtcatac tcctattcac cgttctcaac tactcataca tgccctgctc ttgtttacac 4620 tgccagttta cactgtttct ccaagccagc acagctgata tctcctggtg ctatccccaa 4680 accgccactc ttaactctta aagtaaataa ataatcttta ctggcaaggc tatgctgaac 4740 caccttaggc actctctaat tagatgtcgt aggtcctccc aattctgagt cctttaatac 4800 ctgtttttct ccttctctta ttctgtttag tttttcaatt catacaaaac tgtatccagg 4860 ccaacaccaa taattctaaa taacaaatgt ttcttctaac agccccacaa tatcacccct 4920 tgccacaaaa ttttccttca gcttaatctc tcccactcta ggttcccacg ccgcccctaa 4980 tcccgctcga agcagccctg agaaacatca cccattatct ctccatacca ccaaaaaatt 5040 ttcactgtcc caacacttta ccactatttc attttattgt tcttattaat ataagaagac 5100 aggaatgtca ggcctctgag cccaagctaa gccatcacat accctgtgac ctgcaggtac 5160 acatccagat ggctggttcc tgccttaact gctgacattc caccacaaaa gaagtgaaaa 5220 tgtcctgttc ctgccttaac tgatgacatt gtcttgtgaa attccttctc ctggctcatc 5280 ccggctcaaa agctccccca ctgagtacct tgtgaccccc actctgccgg ccagagaaca 5340 cccccctttg actgtaattt tcctttatct acccaaatcc tataaaacgg ccccacccct 5400 atttcccttc gctgactctc tttttggact cagcccacct gcacccaggt gaaataaaca 5460 gctttattgc tcacacaaag cctgtttgat ggtctcttca catggatgag agtgaaa 5517 <210> 52 <211> 3427 <212> DNA <213> Homo sapiens <400> 52 gtcaggcctc tgagcccagg ccaggccatc acatcccctg tgacttgcac gtatacatcc 60 agatggcctg aagtaactga agatccacaa aagaaataaa aacagcctta actgatgaca 120 ttccaccatt gtgatttgtt cccgccccac cctaactgat caatgtactt tgtagtctcc 180 cccaccctta agaaggttct ttgtaattct ccccactctt gagaatgtat tttgtgagat 240 ccacccctgc ccaccagaga acaaccccct ttgactgtaa ttttccatta ccttcccaaa 300 tcctataaaa cggccccact cccttcgctg actctctttt cggactcagc ccgcctgcac 360 ccaggtgaaa taaacagcca tgttgctcac acaaagcctg tttggtggtc tcttcacacg 420 gacgcgcatg aaatgtggtg ccgtgactcg gatcggggga cctcccttgg gagatcaatc 480 ccccgtcctc ctgctctttg ctccgtgaga aagatccacc tctatgacct caggtcctca 540 gaccgaccag cccaagaaac atctcaccaa tttcaaatcc ggtaagcggc ctcttttgac 600 tctcttctcc aacctccctc actatccctc aacctctttc tcctttcaat cttggtgcca 660 cacttcaatc tctcccttaa tttcaattcc tttcattttc tggtagagac aaaagagaca 720 cgttttatcc gtggacccaa aactccggcg ccggtcacgg actgggaagg cagccttccc 780 ttggtgttta atcattgcag ggacgctctc tgattataca cccacgtttc aagggtgtca 840 gaccacgcag ggacgcctgc cttggtcctt cacccttagc ggctagtccc gcttttctgg 900 ggaaggggca agtacccgtg aaccccttct ccttcaccct cagcggcaag tcccgctttc 960 ctggggcagg ggcaagtacc cctcaacccc ttctccttca ccctcagcgg caagtcccac 1020 tttcctgggg caggggcaag tacccctcaa ccccttctcc ttcaccctta gcggcaagtc 1080 ccgcttttct agggggcaag aacccccaaa ccccttccct ccgggtctct atgctctctt 1140 ttctctgggt ttgcttcctt cactatgggc aaccttccac cctccattcc tcctccttct 1200 cccttagcct gtgtgctcaa gaacttaaaa cctcttcaac tcacacctga cctaaaacct 1260 aaatgcctta ttttcttctg caatgccgct tgaccccaat acaaactcaa cagtagttcc 1320 aaatagccag aaaatggcac tttaaatttt tccatcctgc aagatctaaa taattcttgt 1380 cgtaaaatag gcaaacggtc tgaggtgcct gacgtcccgg cattctttta cacatcagtc 1440 ccttcctagt cgctgtgccc agggcaactc ctcccaaatc ttccttcttt ccctcccgcc 1500 tgtcccctca gtcccaaccc caagcatcac tgactctttc taatcttcct tttctacaga 1560 cccatctgac ctctcccctc ctcaccaggc cgagctaggt cccaattctt cctcagcctc 1620 cgctcctcca ccctataatc cttttatcac ctcccctcct cacacctggt cctgcttatg 1680 gttttcattc cgtgactagc cctcccccac ctgcccagca atttactctt aaaaaggtgg 1740 ctggagctga aggcatagtc aaggttaatg ctcctttttc tttatcccaa atcagatagc 1800 gtttaggctc tttttcatca aatataaaaa cccaacccag ttcatggcag caaccctgag 1860 acgctttaca gccctagacc ctaaaaggtc aaaaggctgt cttattctca atatacattt 1920 tattacccaa tctgctcccg acattaaata aaactccaaa aattaaattc cggccctcaa 1980 accccacaac aggattgaat taacctctcc ttcaaggtgt acaataatag gaaaaagttg 2040 caattccttg cctccactgt gagacaaatc ccagccacat ctccagcaca caagaacttc 2100 caaacgcctg aaccgcagtg gccaggtgtt cctccagaac ctcctccccc aggagcttgc 2160 tacaagtgcc agaaatctga ccaccaggcc aaggaatgcc cgcagcccag gattcctcct 2220 aagccgtgtc ccatctgtgc gggaccccac tggaaattgg actgttcaac tcacctggca 2280 gccactccca gagcccctgg aactctggcc cgaggctctc tgactgactc cttctcggct 2340 tagcggctga agactgatgc tgcccgatcg cctcggaagc cccatagacc atcacggacg 2400 ccgagcttcc ggtaactctc acagcggaag gtaagcccgt ccccttctta agcaatacgg 2460 aggctaccca ctccacatta ccttcttttc aagggcctgt ttcccttgcc tccataactg 2520 ttgtgggtat tgacagacag gcttctaaac ctcttaaaac tccccaactc tggtgccaac 2580 ttagacaata ctcttttatg cactcttttt tagttatccc cacctgccca gttcccttat 2640 tagaccgaga tattttaacc aaattatctg cttccctgac tattcctgga ctacagctgc 2700 atctcattgc tgcccttctt cccaatccaa agcctccttt gcgtcctcct cttgtattcc 2760 cccaccttaa cccacaagta taagagacct ctactccctc cttggcaact gatcacgcac 2820 cccttaccat ctcattaaaa cctaatcatc cttaccccgc tcaatgccaa tatcctatcc 2880 cacagcacga tttaaaagga ttaaagcctg tgatcactcg cctgctacag cacgggcttc 2940 taaaacctat aaactctcct taccattccc ccattttacc tgtcctaaaa ccagacaagg 3000 cttacaagtt agttcagaat ctgcgcctta tcaaccaaat tgttttgcct atccaccccg 3060 tggtgccaaa cccatatact ctcctatcct caataccttc ctctactacc cattattctg 3120 ttctggatct caaacatgct ttctttacta ttcctttgca cccgtcatcc cagcctctct 3180 ttgccttcac ttagactgac cctgacaccc attaggctca gcaaattacc tgggctgtac 3240 tgccgcaagg cttcacagac agcccccatt acttcagtca agcccaaatt tcgtcctcat 3300 ctgttaccta tcttggcata attctcataa aaacacatgt gctctccctg ctgatcgtgt 3360 ctgattaatc tcccaaacct caatccctta caaaagaaca actcctttcc ttcctaggca 3420 tgcttag 3427 <210> 53 <211> 2930 <212> DNA <213> Homo sapiens <400> 53 aactcagatc gggggacctc ccttgggaga tcaatcccct gtcctcctgt tctttgctcc 60 atgagaaaga tccacctatg acctcaggtc ctcagaccaa ccagcccaag gaacatctca 120 ccaattttaa atcgggtaag cggcctcttc ttactctctt ctccaacctc tctcactaaa 180 ccctcaacca ctttctcctt tccactcttc aatctctccc ttctcttaat ttcaattcct 240 tttgttttct ggtagagaca aaggagacac gttttatccg tggacccaaa actccggcac 300 cagtcacgga atagggaagg cagccttccc ttggtgttta atcattgctg ggatgccttt 360 ctgattattc aggtgtcaga ccacgcaggg acgcctgcct tggtccttca cccttagcgg 420 caagtcccgc ttttctgggg aaggggcaag taccccaacc ccttatatct ctgtgccccg 480 atcccttatt tccgcacccc aacctcatat ctctgcgccc caatccctta tgtccgcacc 540 ccgacctcgt atctctgtgc cctgacccct ttcccgcttt tctggagggt aagaaccccc 600 gaaccccttc cctccatgtc tctactctct cttttctctg ggcttcacta tgggcaacct 660 tccaccctca atttctcctt attctccctt agcctgtgtt cttaagaact taaaacctct 720 tcaactctca cctgacctaa aatctaagtg tcttattttc ttctgcaatg ccgcttgacc 780 ccaatacaaa gtcgacagta gttccaaata gccagaaaac gacactttca atttttccat 840 cctgcaagat ctaaataatt cttgtcgtaa aataggcaaa tggtctgaga tgcctgacgt 900 ccaggcactc ttttacacat cggtcccttt ccagtctctg ttcccaatgc aactcatcac 960 aaatcttcct tctttccctc ccacctgtcc cctcagtccc aaccccaagc gtcgctgagt 1020 ctttctaatt ttccttttct acagacccat ctgacctctt cccttctccc caggctgctc 1080 ctcaccaggc tgagctaggt cccaattctt gctcagcctc tgctcctcca ccctataatc 1140 cttttatcac ctcccctcct cacacccggt ccggcttaca gtttcgttcc atgactagcc 1200 ctccccctcc tgcccagcaa tttactctta aaaaggtggc tggagctaaa ggcatagtca 1260 aggttaatgc tcctttttct ttatcccaaa tcagatagcg tttaggctct ttttcatcaa 1320 atataaaaat ccagcccagt tcatggctcg ttcggcagca accctgagac actttacagc 1380 cctagaccct aaaaggtcaa aaggccgtct tattctcaat atacatttta ttacccaatc 1440 tgctcccgac attaaataaa actccaaaaa ttaaattccg gccctcaaac cccacaacag 1500 gatttaatta acctcgcctt caaggtgtac aataatagaa aaaagttgca attccttgcc 1560 tccactgtga gacaaacccc agccacatct ccagcacata agaacttcca aacgcctgaa 1620 ccgcagcagc ccggcattcc accagaacct cctcccccag gagcttgcta caagtgccag 1680 aaatctgacc accaggccaa ggaatgcctg cagcccagga ttcctcctaa gccatgtccc 1740 atctgtgcgg gaccccactg gaaatcagac tgttcaactc acctggcagc cactcccaga 1800 gcccctggaa ctctggccga aggctctctg actgactcct tctcggctta gcggctgaag 1860 actgacgctg cctgatagcc ttggaagccc cgtagaccat cacggacgcc gagccttagg 1920 taactctcac agtggagggt aagtccgtcc ccttcttaat caatacggag gctacccact 1980 ccacattacc ttcttttcaa gggcctgttg cccttgcctc cataagtgtt gtgcgtattg 2040 acagccaggc ttctaaacta aaactcccca actctggtgc caacttagac aatactcttt 2100 taagcactcc ttttagttat ccccacctgc ccagttccct tattaggccg agacacttta 2160 actaaattat ctgtttccct gactattcct ggattacagc tacatctcat tgccgccctt 2220 cttcccaatc caaagcctcc tttgcgtcct cctcttgtat ctccccacct taacccacaa 2280 gtataagata cctctactcc ctccttggcg accgatcatg caccccttac catctcatta 2340 aaacctaatc acccttactc cgctcaatgc caagatcccg tcccacagca cgctttaaaa 2400 ggattaaagc ctgttgtcac tcgcctgcta cagcgtggcc ttttaaatcc tataaactct 2460 tcttacaatt cccccatttt acctgtccta aaaccagaca agccttacaa gttagttcag 2520 gatctgcatc ttatcaacca aattgttttg cctatccacc ccatggtgcc aaacccatat 2580 actctcctat cctcaatacc tccctccaca atcccttatt ctgttctgga tctcaaacat 2640 gctttcttta ctattccttt gcacccttaa tcccagcctc tcttcgatgt cacctggact 2700 gaccctgaca cccattaggc tcagcaaatt acctgggctg tactgccgca aggcttcaca 2760 gacagccccc attacttcag tcaagcccaa atttcttcct catctgttac ctatctcagc 2820 ataatgctca taaaaacaca cgtgctctcc cagctgatca tgttcgatta atctcccaaa 2880 cctcaatccc ttacaaaaca acaactcctt tccttcctag gcatagttag 2930 <210> 54 <211> 5525 <212> DNA <213> Homo sapiens <400> 54 gtcaggcctc tgagctgaag ctaagccatc atatcccctg tgacctgcac gtacacatcc 60 agatggccgg ttcctgcctt aactgatgac gttccaccac aaaagaagtg aaaatggcct 120 gttcccgcct taactgatga cattgtcttg tgaaattcct tctcctggct catcctggct 180 caaaagctcc cctgctgagc accttgtgac cttcccgcct ccccccaccc cgctctgccc 240 gccagagaac aaaccccttt gactgtaatt ttcctttatc cacccaaatc ctataaaacg 300 gccccaccct tatctccctt tgctgactct cttttcggac tcagcccgcc tgcacccagg 360 tgaaataaac agccatgttg ctcacacaca gcctgtttgg tggtttcttc acacggccgc 420 gcatgaaatt tggtgccgtg actcggatcg ggggacctcc cttgggagat caatccccca 480 tcctcctgct ctttgctgtg tgagaaagat ccacctatga cctcaggtcc tcagaccgac 540 cagcccaaga aacatctcac caatttcaaa tccggtaagc ggcctctttt tactctcttc 600 tccaacttcc ctcactatct ctcaacctct tgctcctttc aatcttggtg ccacacttca 660 atctctccct tctctcaatt tcaattcctt tcatattctg gtggagacaa aggagacacg 720 ttttatccat ggacccaaaa ctccagcgct ggtcacagac tgggaaggta gccttccctt 780 ggtgtttaat cattgcaggg acgcctctct gattattcac ccatgtttca aaggtgtcag 840 accacgcagg gacgcctgcc ttggtccttc acccttagcg gcaagtcccg cttttctgag 900 ggaggggcaa gtacccctca accccttctc cttcaccctt agcggtaagt cccgcttttc 960 tatggggcaa gaacccccaa tcccttattt ccacaccccg acccctttcc cgcttttctg 1020 gagggtaaga acccccgaac ctcttccctc cgtgtctcta ctctctcttt tctctgggct 1080 tgcctccttc actatgggca agcttccacc ttccatttct ccttcttctc cctaagcctg 1140 tgtcctcaag aacttaaaac ctcttcaact cacacctgac ctaaaaccta aatgccttat 1200 tttcttctgc aatgccgctt gaccccaata caaactcgac agtaattcca aatagccaga 1260 aaatggcact ttgaattttt ccatcctgca agatctaaat aattcttgtc gtaaaatagg 1320 caaacggtct gaggtgcctg acgtccaggc attcttttac acatcggtcc cttcctagtc 1380 tctgtgccca gtgcaactca tcccaaatct tccttctttc cctcccgcct gtcccctcag 1440 tcccaacccc aagcatcgct gagtctttct aatcttcctt ttctacagac ccatctgacc 1500 tctcccctcc tcgccaggcc gagctaggtc ccaattcttc ctcagcctcc gctcctccac 1560 cctataatcc ttttatcacc tcccctcctc acacccggtc cagcttacag tttcgttccg 1620 tgactggccc tcccccacct gcccagcaat ttactcttaa aaaggtggct ggagctaaag 1680 gcatagtcaa ggttaatgct cctttttctt tatcccaaat cagatagcgt ttaggctctt 1740 tttcatcaaa tataaaaacc cagcccagtt catggctcgt ttggcagcaa ccctgagacg 1800 ctttacagcc ctagacccta aaaggtcaaa aggccgtctt atgctcaata tacattttat 1860 tacccaatct gctcccgata ttaaataaaa ctccaaaaat taaattccgg ccctcaaact 1920 ccacaacagg atttaattaa cctcgccttc aaggtgtaca ataatagaaa aaagttgcaa 1980 ttccttgcct ccactgtgag acaaacccca gccacatctc cagcacacaa gaacttccaa 2040 acgcctgaac ctcagcggcc aggcattcct ccggaacctc ctcccccagg agcttgctac 2100 aagtgcccga aatctgacca ccaggccgag gaatgcctgc agcccaggat tcctcccaag 2160 ccgtgtccca tctgtgcggg accccactgg aaatcggact gttcaactca cctggcagcc 2220 actcccagag cccctggaac tctggcccaa ggctctctga ctgactcctt ctctgcttag 2280 cagctaaaga ctgacattgc ccgatagcct cggaagcccc gtagaccatc acggatgccg 2340 agctttaggt aaccctcaca gtggaaggta agtccgtccc cttcttaatc aatacggagg 2400 ctacccactc cacattacct tcttttcaag ggcctgtttc ccttgcctcc ataactgttg 2460 tgggtattga cagccaggct tctaaacccc ttaaaactcc ccaactctgg tgccaactta 2520 gacaatactc ttttaagcac tcctttttag ttatccccac ctgcccagtt cccttattag 2580 gccgagatat tttaaccaaa ttatctgctt ccctgactat tcctggacca cagccgcatc 2640 tcattgctgc ccttcttccc aatccaaagc ctcctttgcg tcctcctctt ttgtattccc 2700 ccccacctta acccacaagt ataagatacc tctactccct ccttggcgac caatcatgca 2760 ccccttacca tctcattaaa acataatcac ccttacccca ctcaatgcca atatcccatc 2820 ccacagcatg ctttgaaagg agtaaagcct gttatcacat gcctgctaca gcatggcctt 2880 ttaaagccta taaactctcc ttacaattcc cccattttac ctatcctaaa accagacaag 2940 ccttacaagt tagttcagga tctatgcctt atcaaccaaa ttgttttgcc tatccacccc 3000 atggtaccaa accatatact ctcctatcct caatacctcc ctccacaatc cattattctg 3060 ttctggatct caaacatgct ttctttacaa ttcctttgca cccgtcatcc cagcctctct 3120 ttgctttcac ttggactgac cctgacatcc attaggctca gcaaattacc cgggctgtac 3180 tgctgcaagg cttcacagac agcccccatt acttcagtca agcccaaatt tcatcctcat 3240 ctgttacctg tctcagcata attctcataa aaacacacgt gctctccctg ctgatcatgt 3300 ctgattaatc tcccaaacct caatccctta caaaacaaca actcctttcc ttcctaggca 3360 tggttagtga ggtcagaatt cttacacaag agccaggacc gcaccttgta gcctttctgt 3420 ccaaacaact tgaccttact gttttagcct agccctcaag tctgcgtgca gcggctgccg 3480 ctgctttaat acttttagag gccctaaaaa taacaaacta tgctcaactc actctctaca 3540 tttctcataa cttccaaaat tattttcttc ctcatacctg atgcatatac tttctgctcc 3600 ctggctcctt cagctgtact cactctttgt taagtcccac aattaccatt gttcctggcc 3660 cggacctcaa tctggcctcc cacattattc ctgataccac acctgacccc catgactgta 3720 tctctctgat ccacctgatg ttcttcccat ttccccacat ttccttcttt cctgtttctc 3780 accctgatca cgcttgattt attgatggca gttccagcag gcctaatcac cacacagcag 3840 caaaagcagg ctatgctata gtacaagcca ctagcccgcc tcttagaacc tcatttcctt 3900 tccattgtgg aaatctatcc tcaaggaaat aacttctcag tgttccatct gctattctgc 3960 tactcctcaa ggattcttca ggccccctcc cttccctaca catcaagctc aaggatttgc 4020 ccccgcccag gactggcaag ttagctttac tcaacatgca ccgagtcaca aaaactaaaa 4080 tacctcttag tctaggtaga cactttcact ggataggtag aggcctttcc tacagggtct 4140 gagaaggcca cacagtcatt tcttcccttc tgtcagacat aattcctcag tttagccttc 4200 ccacctctat acagtctgat aacagaccag cccttattag tcaaatcagc caagcagttt 4260 ctcaggctct tagtattcag tgaaaccttt atatccctta cggtcctccg tcttcaggaa 4320 aagtagaacg gactaaaggt cttttaaaaa cacttcacca agctcagcca ccaacttaaa 4380 aaggactgga caatactttt accactttcc cttctcagaa gtcagacctg tcctcagaat 4440 gctacaaggt acagcccatt tgagctcctg tatagacgtt cctttttatt tggtcccagt 4500 ctcattccag acaccagacc aacttagact gtgccccaaa aaacttgtca tccctactat 4560 cttctgtcta gtcatactcc tattcaccat tctcaactac tcatgcattc cctgctcttg 4620 tttacactgc tggtttacac tatttctcca agccatcaca gctgatatct cctggtgcta 4680 tccccaaact gccactctta actcttgaag taaataaata atctttgctg gcaaggctat 4740 gctgaatctc cttaggtact ctaattagat gtcctaggtc ctcccaattc ttagaccttt 4800 aatacctgtt tttctccttc tcttattccg tttagttttt caattcatac aaaaccgtat 4860 ccaggccatc accaataatt ctaaatgaca aatgtttctt ctaatagtcc cacagtatca 4920 ccccttacca caaaatcttc cttcagctta atctctccca ctctaggttc ccacgccgcc 4980 cctaatcccg ctcgaagcag ccctgagaaa catcacccat tatctctcca caccaccccc 5040 aaaaattttc accgtcccaa cactttacca ctatttcatt ttatttttct tattaatata 5100 agaagacagg aatgtcaggc ctctgagccg aagctaagcc atcatatccc ctgtgacctg 5160 cacgtacaca tccagatggc cggttcctgc ctcaactgat gacattccac cacaaaagaa 5220 gtgaaaatgg cctgctcccg ccttaactga tgacattgtc ttgtgaaatt ccttctcctg 5280 gctcattctg gctcaaaagc tcccctgctg agcaccttgt gacccccact ctgcccacca 5340 gagaacaaac cccctttgac tgtaattttc ctttatccac ccaaatccta taaaatggcc 5400 ccacccttat ctcccttcgc tgactctctt ttcggactca gcccacctgc acccaggtga 5460 aataaacagc catgttgctc acccaaagcc tgtttggtgg tctcttcaca cggacgtgca 5520 tgaaa 5525 <210> 55 <211> 5745 <212> DNA <213> Homo sapiens <400> 55 gtcaggcctc tgagcccagc taagccatca tatcccctgt gacctgcaca tacacaccta 60 gatggccagt tcctgcctta accaatgaca gtccaccaca aaagaagtga aaatggcctg 120 ttcctgcctt aactgatgac attatcttgt gaaattcctt ctcctggctc atcctggctc 180 aaaacgtccc ctgctgagca ccttgtgacc ccccactcct gcctgccaga gaacaacccc 240 acttcttcct ttacctaccc aaatcttata aaatggcccc accctatctc cctttgctga 300 ctgtctttcg gactcagccc ggttgcaccc aggtgaaata aacagccttg ttgctcacac 360 aaagccggtt tggcggtctc ttcacacaga cgtccatgaa atttggtgcc gtgactcgga 420 tcgggggacc tcccttggga gatcaatccc ctgctctcct gctctttgct ccgtgagaaa 480 gatccaccta tgacctcagg tcctcagacc gaccagccca aggaacatct cactaatttc 540 aaatctggta agtggcctct ttttactctc ttctccaacc tccttcacta tccctcaacc 600 tctttctcct tcaatcttgg caccacactt caatctctcc tttctcttaa cttcagttcc 660 tttccttttc tggtagagac aaaggagatg cgttttatcc atggacccaa aactccggcg 720 ccggtcacgg actcaggaag gcaggcttcc cttgctgttt aatcattgcg ggacgcctct 780 ctgattattc acccacgttc cattggtgtc tgatctccgt ggggatgcct gccttgatca 840 ttcacccatg ttcccttggt ggcaagtcaa ttgcggggac gcctgctttg gctgctcacc 900 cacattgcag cccagagctg ctccccaccc ccttctccgt gtctctaccc ttctctttaa 960 acttgcctcc ttcactatag gcaaccttcc accctccatt cctcctcctc ccttagcctg 1020 tattctcaag aacttaaaac ctcttcaact cacacctgac ctaaaaccta aacaccttat 1080 tttcttctac aatgacactt gaccccaata caaactcgac agtagttcca aatagccaga 1140 aaatggcact tgctattttt ccatcccaca agatctaaat aattcttgtc gtaaaatagg 1200 caaatggtct gaggtgcctg acgtccaggc attcttttac acattggtcc ctccctagtc 1260 tctgttccca atgcaactcg tcccaaatct tccttctttc cctcctgcct gtcccctcag 1320 tcccaacccc aagtgtcact gagtctttct aatcttcctt ttctacagat ccatctgacc 1380 tctccccagc tcggcaggcc aagctaggtc ccaattcttc ctcagcctct gctcctccac 1440 cctataatcc ttttatcacc tcccctcctc acactcggtc tggcttacag tttcattctg 1500 tgactagccc tcccccacct gcccggcaat ttcctcttaa aaaggtggct ggagctaaag 1560 ccataatcaa ggttaatgct cctttttctt tatcgcaaat cagatagcat ttaggctctt 1620 tttcatcaaa tataaaaatc cagcccagtt catggcttgt ttggcagcaa ccctgagatg 1680 ctttacagcc ctagacccta aaaggtcaaa aggccatctt attctcaata tacattttat 1740 tacccaatcc actcccaaca ttaaataaaa ctccaaagac taaattccag ccctcaaacc 1800 cctcaacagg acttaattaa ccttgccttt gaggtgtaca ataatagagt agaggcagcc 1860 aaatagcaac atattcctga gttgcaattc cttgcctcca ctgtgagaca aaccccagcc 1920 acatctccag cacacaagaa cttccaaacg cctaaaccgc agtggccagg cattcctcca 1980 gaactgcctc ccccaggagc ttgctacaag tgccagaaat ctggccacca ggccaaggga 2040 tgcccgcagc ccaggattcc tcctaagcca catcccatct gtgcaggacc ccactggaaa 2100 tcagactgtc caactcacct ggcagccact cccagagccc ctggaactct ggcccaaggc 2160 tttctgactg actccttccc agatcttctc ggcttagcag ctgaagactg acactgccca 2220 atggcctcag aagcccccta gaccatcatg gatgccgagc ttcgaatagc tctcacagtg 2280 gaaactaagt ccgtcccctt cttaatcaat acggaggcta cccactccac attaccttct 2340 tttcaagagt ctgtttccct tgcctccata actgttgtag gtattgatgg ccaggcttct 2400 aaacctctta aaactcccca actctggtgc caacttagac aatacctttt taagcactcc 2460 tttttagtta tccccacctg cccagttccc ttattaagct gagacatttt aactaaatta 2520 tctgcttccc tgactattcc tggactacag ccacatctca ttgccacctt tcttcccaat 2580 ccaaagcctc ctttgtgtcc tcctcttgta cctgcccccc ccaccttaac ccacaagtat 2640 aggatacctc tactccctcc ttggtgaccg atcatgcact ccttaccatc tcattaaaac 2700 ctaatcaccc ttaccccgct caatgccaat atcccatccg cagtgcactt taaaaagatt 2760 aaagcctgtt atcactcgcc tgctacagca tggcctttta aagcctataa actctcctta 2820 caatttcccc attttacctg tcctaaaacc agacaagcct tacaagttag tttaggatct 2880 gcgccttatc aaccaaattg ttttgcctat ccatcctgcg gtgccaaacc catagactct 2940 cctatcctca atacctccct ccacaaccca ttattctgtt ctggatctca aacatgcttt 3000 ctttactatt cctttgcact cttcgtccca gcctctctct gctttcactt ggactgaccc 3060 ttggactgac cctgacatgc atcacgctca gcaaattacg tgggctgtac tgccgcaaag 3120 cttcacaaac agtccccatt acttcagtca agcccaaatt tcgtcctcat ctgttaccta 3180 tctcggcata atgctcataa aaacacacgt gctctccctg ccaatcatgt ctgactgatc 3240 tctcaaaccc caacaccttc tacaaaacaa ctcctttcct tcctaggcat ggttacatac 3300 tttcaacttt agatacctgg ttttgccatc ctaacaaaac cattatataa actcacaaaa 3360 ggaaacctag ctgaccccat agatcctaaa tccttttccc actcctcttt ccattccttg 3420 aagacagctt tagagactgc ccccacccta gctctccctg actgatccca acccttttca 3480 ttacccacag ccgaagtgca gggctgtgca gtcagaattc ttacacaaga accgggaccg 3540 tgccctgtag cctttttatg caaacaactt gaccttactg ttttgcctag ccctcaagtc 3600 tgcgtgcagt ggccgccacg accctaatac tttcagaggc ccttaaaatc acaaactatg 3660 ttcaactcgc tctctacagt tctcataact tccaaaatct attttcttcc tgacacctga 3720 cacatatact ttctgctccc cagctccttc agctgtactc actctttgtt gagtctccca 3780 caattatcat tgttcctggc ccagacttcc atccggcctc ccacattatt cctgatacca 3840 cacctgaccc ctatgactgt atctctctga tccacctgac attcacccca tttccccgta 3900 tttccttctt tcatgttcct caccctgatc acacttggtt tattgatggc agttccacca 3960 ggcctaatcg ccacacacca gccaaggcag gctatgctat agtagaagcc actagcctac 4020 ctcttagaac ctctcatttc ctttccatca tggaaatcta tcctcaaaga aataacttct 4080 cagtgttcca tctgctattc tactatttct cagggatgat tcaggccccc tcccttccct 4140 acacatcaag ctcagggatt tgcccccacc caggactagc aaatttgcta ttctactact 4200 tctcagggat tattcaggcc ccctccgtcc ctacacatca aactcaagga tttgcccctg 4260 cccagaactg gcaaattgac tttactcaac acgccccgag tcaggaaact aaaatacctc 4320 ttggtctagg tagacacttt cactggatag gtagaggcct ttcccacagg gtctgagaag 4380 gccaccatgg tcatttcttc ccttctgtca gacataattc ctcggtttgg ccttcccacc 4440 tctatacagt ccgatagcag accggccttt attagtcaaa tcagccaagc aggttttcag 4500 gctcttggta ttcagtgaaa cctttatatc ccttatggtc ctcagtcttc aggaaaggta 4560 gaatggacta aaggtctttt aaaaacacac ctcaccaagc tcagccacca acttaaaaag 4620 gactggacga tacttttacc actttccctt ctcagaattc atgcctgtcc tcagaatgct 4680 acagggtaca gcgcatttga gctcctgtat agacgctcct ttttattagg ccccagtctc 4740 attccagaca gcagaccaac ttggactgtg ctccaaaaaa cttgtcatcc ctactatctt 4800 ctctctagtc atactcctat tcaccattct caactactca tacatgccct gctcttgttt 4860 acactgccgg cttacactgt ttctccaagc catcacagct gatatctcct ggtgctatcg 4920 ccaaaccacc actcttaact cttaaagtaa ataaataatc tttgctggca aggctattct 4980 gaatctcctt aggcattctt taattagatg tcctaggtcc tcccaattct tagtccttta 5040 atacctgttt ttctccttct cttattccgt tcagtttttc aattcataca aaacagcatc 5100 caggccatca ccaataattc tacatgacaa atgtctcctc taacaacccc acaatatcac 5160 cccttaccac aaaatcttcc ttcagcttaa tctctcccac tctaagttcc caagccgccc 5220 ctaatcctgc tcgaagcagc cccgagaaac accgcccgtt atctctccat accacccccc 5280 aaaattttcg ccatcccaac actttaccac tatttcattt tatttttctt attaatataa 5340 gaaaacagga atgtcaggcc tctgagccca agctaagcca tcatatcccc tgtgacctgc 5400 acatacacat ccagatggct ggttcctgcc tttactgatg acattccacc acaaaagaag 5460 tgaaaatggc ctgttcctgc cttaactgat gacattatct tgtgaaattc cttctcctgg 5520 ctcaagacct cccctactga gcaccccgtg acacccccca ctcctgcctg ccagagaaca 5580 accccctttt tcctttaaac gcaaatctta tcaaacgggc ccacccctat ctcccttcgc 5640 tgactctctt ttcggactcg gcctgcctgc acccaggtga aataaacagc cttgttgctc 5700 acacaaagcc tgtttgatgg tttcttcaca cagacgtgca tgaaa 5745 <210> 56 <211> 5823 <212> DNA <213> Homo sapiens <400> 56 gtcaggcctc tgagtccaag ccaagccatt gcatcccctg tgacttgcac gtatataccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aagatcctgc cccgccttaa 120 ctgatgacat tccaccattg tgatttgttc ctgccccacc ttaactgagt gattaaccct 180 gtgaatttcc ttctcctggc tcagaagctc ccccactgag caccttgtga cccctgcccc 240 tgcccaccag agaacaaccc cctttgactg taattttcca ttaccttccc aaatcctata 300 aaatggcccc accccatctc ccttcgctga ctctctttcc ggactcagcc cacctgcacc 360 caggtgaaat aaacagcttt attgctcaca caaagcctgt ttggtggtct cttcacacgg 420 atgcgcatga aatttggtgc cgtgactcgg atcgggggac ctctcttagg agatcaatcc 480 cccgtcctcc tgctctttgc tccatgagaa agatccacct atgacctcag gtcctcagac 540 cgaccagccc aagaaacatc tcaccaattt caaatctggt aagcggcctc ttttcactct 600 cttctccaac ctccctcact atccctcaac ctctttctcc tttcaatctt ggtgccacac 660 ttcaatctct cccttctctt aatttcaatt cctttcattt tctggtagag acaaaggaga 720 caccttttat ccttggaccc aaaactccgg cgccagtcac agactgggaa ggcagccttc 780 tcttggtgtt taatcattgc agggacacct ctctgattat tcacccacgt ttcaagggtg 840 tcagaccacg cagggacgcc tgccttggtc cttcaccctt agtggcaagt cctgcttttc 900 tggggaaggg gcaagtaccc caaccccttc tctccttgtc tctactcctt ctctgctttt 960 ctggggaagg ggcgagtacc ccaacccctt ctctccttgt ctctacccct tctctgcttt 1020 tctggggaag gggcaagtac cccaacccct tctctccttg tctctacccc ttctctgctt 1080 ttctggggga gggcaagtac ccctcaaccc cttctccttc acccttagcg gcaagtccca 1140 ctttgctagg gggaaagaac ccccaatccc ttatttccac accccgacct cttatctctg 1200 tgccccaatc ccttatttcc acaccccgac ctcttatctc tgtgccccaa tcccttattt 1260 ccgcacccca acctcttatc tctgtgcccc aattccttat ttccatgccc caacacttcc 1320 tctgcttttc tggagggcaa gaaaccccta ccccttctcc gtgtctctac tcttttctct 1380 gggcttgcct ccttcactat gggcaagctt caaccttcca ttcctccttc ttctccctta 1440 acctatattc ttaagaactt aaaacctctt caactctcac ctgacctaaa atctaagcat 1500 ctcattttct tctgcaatgc cacttgaccc caatacaaac tcgatggtag ttccaaatag 1560 ccagaaaatg gcactttcaa tttttccatc ctacaagatc taaataattc ttgtcataaa 1620 atgggcaaat ggtctgaggt gcctgacatc caggcattct tttacacatc agtcccttcc 1680 tagtctctgt gcccagtgca actcgtccca aatcttcctt ctttccctcc tgcctgtccc 1740 cacagtccca accccaagcg tcactgagtc tttctaatct cccttttcta cagacccatc 1800 tgacctctcc cctcctcacc aggccaagct aggtcccaat tcttcctcag cctctgctcc 1860 tccaccctgt aatcttttta tcgcctcccc tcctcacacc tggtcctgct tgcagttatg 1920 ttccgtgact agccctcccc cacctgctca gcaatttact cttaaaaagg tggctggagc 1980 caaaggcata gtcaaggtta atgctccttt ttctttatcc caaatcagaa gcgtttaggc 2040 tctttttcat caaatataaa aacccagaac agttcatggc tcgttcggca gcaaccctga 2100 gacactttac agccctagac cctaaatggt caaaaggcca tcttattctc aatatacact 2160 ttattaccca atctgctccc gacattaaat aaaactccaa aaattagaat ctggccctca 2220 taccccacaa caggacttaa ttaacctcac cttcaaggtg tacaataata ataaaaaaaa 2280 aaagttgcaa ttccttgcct ccactgtgag acaaacccca gccacatctc cagcacacaa 2340 gaacttccaa acccttgaac tgcagcggcc aggcgttcct ccagaacctc ctcccccagg 2400 agcttgctac aagtgccaga aatctgacca ccaggccaag gaatgcctgc agcccaggat 2460 tcctcctaag ctgtgtccca tctgtgcggg accccactgg aaatcggact gttcaactca 2520 cctggcagcc actcccagag cccctggaac tctggcccaa ggctctctga ctgactcctt 2580 cttggcttag cggctgaaga ctgatgctgc ctgattgcct cggaagccct gtagaccatc 2640 acagatgccg agctttaggt aactctcaca gtggagggta agtccgtccc cttctaaatc 2700 aatacggagg ctactcactc cacattacct tcttttcaag gacctgtttc ccttgcctcc 2760 ataactattg tgggtattga tagccaggct tctaaacctc ttaaaactcc ccaactctgg 2820 tgccaactta gacaatacgc ttttatgcac tcttttttag ttatccccac ctgcccagtt 2880 cccttattag gccgagatat tttaaccaaa ttatctgctt ccctgactat tcctggacta 2940 tagctgcatc tcattgccgc ccttcttccc aatccaaaac ctcctttgtg tcctcttctt 3000 gtattccccc accttaaccc acaagtataa gatacctcta ctccctcctt ggcgaccaat 3060 catgcaccct taccatctca ttaaaaccta atcaccctta ccccactcaa tgccaatatc 3120 ccatcccaca gcatgctttc aaaggattaa agcctgttat cactcgcctg ctacagcatg 3180 gccttttaaa gcctataaac tctcccacaa ttcccccatt ttacctgtcc taaaaccaga 3240 caagccttac atgttagttc aggatctatg ccttatcaac caaattgttt tgcctatcca 3300 ccccatggtg ccaaacccat atactctcct attctcaata cctccttcca caatccatta 3360 ttctgttctg gatctcaaag atgctttctt tactattcct ttgcacccgt catcccagcc 3420 tctctttgct ttcacttgga ctgaccctga cacccatcag gctcagcaaa ttacctgggc 3480 tgtactgcca caaggcttca cagacagacc ccattacttc agtcaggccc aaatttcgtc 3540 ctcatctgtt acctatctca acataattct cgtaaaaaca catgtgctct ccctgctgat 3600 cgtgtctgat taatctccca aacctcaatc ccttacaaaa caacaactcc tttctttcct 3660 aggcatggtt agtgcggtca gaattcttac acaagagcca ggaccgcacc ctgtagcctt 3720 tctgtgcaaa caacttgacc ttactgtttt agcctagcct tcatgtctgc gtgcagcggc 3780 tgctgctgct ttaatacctt tagaggccct caaactcaca aactgtgctc aactcactct 3840 ctacatttct cataacttcc aaaatctatt ttcttcctca tacctgatgc atatactttc 3900 tgctccctgg ctccttcagc tgtactcact cttcattaag acccacaatt accattgttc 3960 ctggccggga cttcaatccg gcctcccaca ttattcctga taccacacct gacccccatg 4020 actgcatctc tctgatccac ctgatgttca tcccatttcc ccacatttcc ttcttccctg 4080 tttctcaccc tgatcatgct tgatttattg atggcagttc caccaggcct aatcaccaca 4140 taccagcaaa ggcaggctat gctattgtat aagccactag cccgcctctt agaacctttc 4200 attttctttc catcgtagaa atctatcctc aaggaaataa cttcttagtg ttccatctgt 4260 tattctgtct gctattctac tacacctcaa ggattattca ggccccctcc cttccctaca 4320 catcaagctc aaggatttgc ccccacccag gactggcaaa ttagctttac tccacatgcc 4380 ctgagtcaca aaaactaaaa tacctcttag tctaagtaga cactttcact agataggtag 4440 aggtctttcc tacagggtct gagaagtcca ccgcagtcat ttcttccctt ctgtcagaca 4500 taattcctca gtttagcctt cccacctcta tacagtctga taacaggcca gcctttatta 4560 gtcaaatcag ccaagcattt tttcaggctc ttagtattca gtgacagact aatggtctat 4620 taaaaacaca cctcaccaag ctcagccacc aacttaaaaa aggactggac aatactttta 4680 ccactttccc ttctcagaag tcaggcctgt cctcagaatg ctacaaggta cagcccattt 4740 gagctcctgt atagacgttc ctttttatta ggccccagtc tcattccaga caccagacaa 4800 acttagactg tgcccccaaa taacttgtca tccctactat cttctgtcta gtcatactcc 4860 tattcaccat tctcaactac tcatacatgc cctgctcttg tttacactgc cagtttacac 4920 tgtttctcca agccgtcaca gctgatatct cctcgtgcta tccccaaact gccactctta 4980 actcttgaag taaataaata atctttgctg gcaggactat gctgaccctc cgtaggcact 5040 ctctaattag atgtcctagg tcctcccaat tcttagtcct tttatacctg tttttctcct 5100 tctcttattc catttagttt ttcaattcat acaaaaccgt atccaggcca tcaccaatca 5160 ttctatatga taaatgtttc ttctaacaac cccacagtat caccccttac cacaaaatct 5220 tccttcagct taatctctcc cactctaggt tcccacacca cccctaatcc cgcttgaagc 5280 agccgtgaga aacatggccc attctctctc cataccaccc ccaaaaattt tcgccgcccc 5340 aacacttcaa cactatttta tttttcttat taatataaga aggcaggaat gtcaggcctc 5400 tgagcccaag ccaagccatt gcatcccctg tgacttacat gtatatgccc agatggcctg 5460 aagtaactga agaatcacaa aagaagtgaa aaggccctgc cctgccttaa ctgatgacat 5520 tccaccattg tgatttgttc ctgccccacc ttaactgagt gattaaccct gtgaatttcc 5580 ttctcctggc tcagaagctc ccccactgag caccttgtga cccccacccc tgcccaccag 5640 agaaaaaccc cctttgactg taattttcca ttaccttccc aaatcctcta aaacagcccc 5700 acccctatct ccctttgctg actctctttt cagactcagc ccacctgcac ccaggtgaaa 5760 taaacagctt tattgctcac acaaagccta tttggtggtc tcttcacacg gacgcgcatg 5820 aaa 5823 <210> 57 <211> 321 <212> DNA <213> Homo sapiens <400> 57 taggtcaggc acaaataagc ccaccctact aggaactatg ttgaaaaatt tcaaaaaaga 60 atttaaagga gactatggag tactgtgaca ctaggaaaac ttaaaacttt gtgtaagata 120 gactggccag cattagaggt aagttggcca ttagaaggaa gcctggacag gtcccttgtt 180 tcaaaggtgt ggcccaaggt aacctgtaag ccagggaatg cagaccagtt cctgtacata 240 gacacttggt tacagctggt tttagacccc ccgcccccaa cacacagtgg ttgagagaac 300 agcagcataa gtggctggca g 321 <210> 58 <211> 6028 <212> DNA <213> Homo sapiens <400> 58 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac atatacgccc 60 agatggcctg aagtaactga agaatcacaa aagaagagaa aaggccctgc cctgccttaa 120 ctgatgacat tccaccattg tgatttgttc ctgccccacc attaaccctg tgaatttcct 180 tctcctggct cagaagctcc ccaactgagc accttgtgac ccctacccct gcccaccaga 240 aaacaacccc ctttgactgt aattttccat taccttccca aatcctataa aacggcccca 300 cccctatctc ccttcgctga ctctcttttt ggactcagcc cgcctgcacc caggtgaaat 360 aaacagccat gttgctcaca caaagcctgt ttggtggtct cttcacatgg acgcgcatga 420 aatttggtgc tgtgactcga attgggggac ctcccttggg agatcaatcc gctgtactcc 480 tgttctttgc tccgtgagaa agatccacct atgacctcag gtcctcagac cgaccagccc 540 aaggaacatc tcaccaattt taaatcaggt aagcggcctc ttcttactct cttctccaac 600 ctctctcact gtccctcaac cactttctcc tttccactct tcaatctctc ccttctctta 660 atttcaattc ctttcatttt ctgggagaga caaaggagac acattttatc cgtgcaccca 720 aaactctggc gccggtcacg gactgggaag gcagccttcc cttggtgttt aaacattgca 780 gggacgcctc tctgattata cacccacgtt tcaaaggtgt cagatcacgc agggacgcct 840 gccttggtcc ttcaccctta gtggcaagtc ctgcttttct ggggaagggg caagtacccc 900 aaccccttct ctccttgtct ctaccccttc tctgcttttc tgggggaggg gcaagtaccc 960 ctcaactcct tctccttcac ccttagcggc aagtcccgct tttctgggag aggggcaagt 1020 acccctcaac cccttctcct tcacccttag tggcaagtcc cgcttttctg ggggaggggc 1080 aagtacccct caaccccttc tccttcaccc ttagtggcaa gtcccgcttt tctgggggag 1140 gggcaagtac ccctcaaccc cttctccttc actcttagcg gcaagtcctg cttttctaga 1200 ggaggggcaa gtaccccaac ctcgtatctc tgcgccccaa tcccttattt ccacgcccct 1260 acctcttatc tctgcgcccc aatcccttat ttctgtgccc cgacccctta tttccatgcc 1320 ccaacccctt atttctgtgc cccatccctt atttccgtgc cccgacctct tatctctgcg 1380 ccccaacccc ttttcccact tttctggaag gtaagaaccg ccgaacccct tctctctgtt 1440 tctctactct ctcttttctc taggcttgct tccttcacta tgggcaacct tccaccctcc 1500 attcctcctt ctactccctt ggcctgtgtt ctcaaaaact taaaacctct tcaactcaca 1560 cctgacctaa aacctaaatg ccttattttc ttctgcaatg ccacttgacc ccaatacaaa 1620 ctcaacagta gttccaaata gccagaaaat ggcactttga atttctccat cctgcaagat 1680 ctaaataatt cttgtcgtaa aataggcaaa tggtctgagg tgcctgacgt ccaggcattc 1740 ttttacacat cagtcccttc ctagcctctg tgcccagtgc aactcgtccc aaatcttcct 1800 tctttccctc ccgcctgtcc cctcagtacc aaccccaagc gtcgctgagt ctttctaatc 1860 ttcattttct acagacccat ctgacctctc ccttcctccc caggctgctc ctcgccaggc 1920 cgagctaggt cccaattctt cctcagcctc tgcttctcca ccctataatc cttttatcac 1980 ctcccctcct cacacctggt ccggcttaca gtttccttcc gtgactagcc ctcccccacc 2040 tgcccagcaa tttactctta aaaaggtggc tggagctaaa ggcatagtca aggttaatgc 2100 tcctttttct ttatcccaaa tcagatagca tttaggctct ttttcatcaa atataaaaac 2160 ccagcccagt tcatggctcg tttggcagca accctgagac gctttacagc cctggaccct 2220 aaaaggtcaa aaggccgtct tattctcaaa atacatttta ttacccaatc tgctcccgac 2280 attaaataaa actccaaaaa ttaaattccg gccctcaaac cccacaacag gatttaatta 2340 acctcgcctt caaggtgtac aataatagaa aaaagttgca attccttgcc tccactgtga 2400 gacaaacccc acaacaggat ttaattaacc tcgccttcaa ggtgtacaat aatagaaaaa 2460 agttgcaatt ccttgcctcc actgtgagac aaaccccagc cacatctcca gcacacaaga 2520 acttccaaac gcctgaaccg cagcggccag gcgttcctcc agaacctcct cccacaggag 2580 cttgctacat atgctggaaa tctggccact gggccaagga atgcccgcag cccgggattc 2640 ctcctaagcc gcatcccatc tgtgtgggac cccactgaaa atcggactgt tcaactcacc 2700 tggcagccac tcccagagcc cctggaactc tggcccaagg ctctctgact gactccttcc 2760 cagatcttct cggcttagcg gctgaagacc gacactgccc gatcacctcg gaagccccct 2820 agaccatcac ggacgccaag cttcaggtaa ctcacagtgg aaggtaaggc cgtccccttc 2880 ttaatctata cggaggctac ccactccaca ttaccttctt ttcaagggcc tgtttccctt 2940 gcctccataa ctgttatggg tattgacagc caggcttcta aacctcttaa aactccccaa 3000 ctctggtgcc aacttagaca ataccctttt aagcactcct ttttagttat ccccacctgc 3060 ccagttccct tattaggctg acgctttaac taaattatct gcttccctga ctattcctgg 3120 actacagcta tatctcattg ccgcccttct tcccaatcca aagcttcctt tgcgtcctcc 3180 tcttgtatcc ccccacctta acccacaagt ataagatacc tctactccct ccttgcacct 3240 cttaccatct cattaaaacc taattaccct taccccactc aacgccaata tcccatcctg 3300 cagcacgctt taaaaagatt aaagcctgtt atcactcgcc tgctacagca tggcctttta 3360 aagcctataa actctcgtta caattccccc attttacctg tcctagaacc agacaagcct 3420 tacaagttag ttcaggatct gcgccttatc aaccaaattg ttttgcctat ccaccccgtg 3480 gtgccaaacc catatactct cctatcctca atacctgcct ctacaaccca ttattctgtt 3540 ctggatctca aacatgcttt ctttactatt cctttgcacc cttcatccca gcctctcttt 3600 gctttcactt ggactgaccc tgacacccat caagctcagc aagttaccta ggctctactg 3660 ccacaaagct tcacagacag cccccattac ttcaatcaag cccaaatttc ttcctcatct 3720 gttacctatc tcggcataat tctcataaaa acacacgtgc tctccctgcc aatcgtgtcc 3780 gactgatctc tcaaacccca gcaccttcta caaaacaaca actcctttcc ttcctaggca 3840 tggttagcgc agtcagaatt cttacataag agccaggacc acaccgtgta gcctttctgt 3900 ccaaacaact tgaccttact gttttagcct agccctcatg tctgcgtgca gcggctgccg 3960 ctgctttaat actgttagag gccctaaaaa tcacaaacta tgctcaactc actctctaca 4020 tttctcatag cttccaaaat ctattttctt cctcatacct gatgcatata ctttctgctc 4080 cccggctcct tcagctgtgc tcgctcttta agtcccacaa tgaccattgt tcctggtccg 4140 gacttcaatc tggcctccca cattattcct gataccacac ctgaccccca tgactgtatt 4200 tctctgatcc acctgatatt caccccattt ccccatattt cattctttcc tgttcctcac 4260 cctgataacg cttgatttat tgacggcagt tccaccaggc ctaattgcca cacaccagca 4320 aaggcaggct atgctatagt acaagccact agcccgcctc tcagaacctc tcatttcctt 4380 tccattgtgg aaatctatcc tcaaggaaat aacttctcag tgttccatct gctattctac 4440 tactcctcag ggattattca ggccccctcc cttccctaca catcaagctc gaggatttgt 4500 ccccacccag gactggcaaa ttagctttac tcaacatgtc ccgagtcagg aaactaaaat 4560 acctcttagt ctaaatagac actttcactg aataagtaaa ggcctttcct acagggtctg 4620 agaaggccac cacagtcatc tcttcccttc tgtcagacat aattcctcag tttagccttc 4680 ccacctctat acagtctgat aacagaccag cctttattag tcaaatcagc caagcagttt 4740 ttcaggctgt tagtattcag tgaaaccttt atatccctta cggtcctccg tcttcaagaa 4800 aagtagaacg gactaaaggt cttttaaaaa cacacctcac caagctcagc taccaactta 4860 aaaaggactg gacaatactt ttaccacttt cgcttctcag aattcaggcc tgtcctcaga 4920 atgctacaag gtacagccaa tttaagctcc tgtatagacg ctccttttta ttaggcccca 4980 gtctcattcg acaccagacc aacttagact gtgccccaaa aaaacttgtc atccctacta 5040 tcttctgtct agtcatactc ctattcaccg ttctcaacta ctcatacatg ccctgctctt 5100 gtttacactg ccggtttaca ctgtttctcc aagccatcat agctgatatc tcctggtgct 5160 atccccaaac tgccacactt aactcctgaa gtaaacaaac aatcttggct ggcaggacta 5220 tgctgaatct ccttaggcac tctctaatca gatgtcctag gtcctcccaa ttcttagacc 5280 ttttatacct gtttttctcc ttcttttatt ccatttagtt tttcaattca tacaaaactg 5340 tatccaggcc atcaccaatc attctataag acaaatgttt cttctaacaa ccccacaata 5400 tcacccctta ccacaaaatc ttccttcagc ttaatctctc ccactctagg ttcccacgcc 5460 gcccctaatc ccgctcgaag cagccctgag aaacatcgtc cattctctct ccataccacc 5520 cccaaaaatt ttcgccgccc caatacttca acactatttt gttttatttt tcttattaat 5580 ataagaaggc aggaatgtca ggcctctgag cccaagccaa gccatcgcat cccctgtgac 5640 ttgcacgtat acgcccagat ggcctcaagt aactgaagaa tcacaaaaga agtgaaaagg 5700 ccctgccccg ccttaactga tgacattcca ccattgtcat ttgttcctgc cccaccttaa 5760 ctgagtgatt aaccctgtga atttccttct cctggctcag aagctccccc actgagcacc 5820 ttgtgacccc tacccctgcc caccagagaa caaccccctt tgactgtaat tttccattac 5880 cttcccaaat cctataaaac ggccccaccc catctccctt cactgactct cttttcggac 5940 tcagcccgcc tgcacccagg tgaaataaac agccatgttg ctcacacaaa gcctgtttgg 6000 tggtctcttc acatggacgc gcatgaaa 6028 <210> 59 <211> 5781 <212> DNA <213> Homo sapiens <400> 59 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgtcctgcac gtacacatct 60 agatggccgg ttcctgcctt aactgatgac attatcttgt gaaattcctt atcctggctc 120 ttcctggctc aaaagctccc ctactgagca ccttgtgacc cccactcctg cctgccagag 180 aacaacccac ctttgactgt aattttcctt tacctacaca aatcttataa aatggcgcca 240 cccctatcgc cctttgctct cttttcagac tcagcccacc tgcacccagg tgattaaaaa 300 gctttattgc tcacacaaag cctgttggtg ggctcttcac atggacacga gtgaaatttg 360 gtgccatgac tcggatcagg ggacctccct tgggagatca atcacctgtc ctcctgctct 420 ttgctccatg agaaagatcc acctatgacc tctggtcctc agaccaacca gcccaaggaa 480 cacctcacca attttaaatc tggtaagtgg cctcttttta ctctcttctt taacctctct 540 cactatccct caacctcttt ctcctttcaa tcttggtgcc acactttgat ctctcccttc 600 tcttaatttc agctcctttc cttttctggt agagatggcg acgcgttttg tttgtggacc 660 caaaactccg acacccgtca tggactcggg aagacagtct tcctttgttg tttaatcatg 720 cgaggatgcc tgcctgatta ttcacccacg tttcagaagt gtctgaccac acggggatgc 780 ctgccttggt ccttcaccct tagcaacaag taccacttta atggggggca agaaaccccc 840 aaccccttct ctccatgtct ctaccccttc tctgcttttc tagggggcaa gaacccccca 900 accccttctc cttcaccctt agtggcaagt accacttttc tagggggcaa gaacacccca 960 accccttctc tccatgtctc taccccttct ctgcttttct gggggacagg aaccccccac 1020 cccttctctc catgtctcta ctctctcttt tctctgggct tgcctccttc actatgggca 1080 agcttccgcc ctccattccc ccttcttctc ccttagcctg tattcttaaa aacctaaaac 1140 ctcttcaact cacacctgac caaaaaccta agtgccttat tttcttctgc aatgctgctt 1200 gaccccaata caaacttgac agtagttcca aatagccaga aaatggcact ttcaattttt 1260 ccatcctaca atatctaaat aattcttgtc ataaaatggg caaacagtct gagatgcctg 1320 atgtccaggc attcttttac acatcagtcc ctccctagtc tctgttccca atgcaactca 1380 tcccaaatct tccctctttc cctcccatct gtcccctcag tcccaacctc aagcatcgca 1440 gagtctttct aatcttcctt ttctacagac ccatctgacc tctcccctcc ttgccaggct 1500 gagctagttc ccaattcttc ctcagtctct gctcctccac cctataatcc ttttatcacc 1560 ttcactcctc acacagggtc cagcttacag tttcgttgtg actagccctc cccaacctgc 1620 ccagcaattt cctcttaaag aggtggctgg agctaaaggc atagtcaagg ttaatgctcc 1680 tttttcttta tcccaaatca gacagcattt aggctcttct ccatcaaatg taaaaaccca 1740 gcccagttca tggctcattt ggcaacaacc ctgagatgct ttacagccct agtccctaaa 1800 aggtcaaaag gctgtcttat tctcaatata cattttatta cccaatcggc tcctgacatt 1860 aaataaaact acaaaaatta aattctggcc ctcaaacccc acaacaggac ttaactaacc 1920 tcaccttcaa ggtgtacaat aatggagtag acacagccaa gtagtaacat atttctgagt 1980 tgcaattcct tgcctccatt gtgagacaaa ccccagccac atctccagca cacaagaact 2040 tccaaatgcc taaaccacag tggccaggca ttcctccagg cctgcctccc tcaggagctt 2100 gctacgagtg ccagaaatct ggccaccaga ccaaggaatg cccgcagtcc aggattcctc 2160 ttaagccatg tcccatcaat gtgggacccc actgaaaatc ggactgttca actcacctgg 2220 cagccactcc cagagcccct ggaactctgg cccaaggctg tccgactgac tccttcccag 2280 atctttttgg cttagtggct caactctgat gctgcccgat cacaatagaa gccccctaga 2340 ccatcacgga tgccaagctt caggtaactt tcacagtggt aggtaagtcc atccccttct 2400 taatcaatat ggagactacc cactccacat tactttcttt tcaagggcct gtttcctttg 2460 cctccataac tgttgtaggt attgacgacc aggcttctaa acctcttaaa actccccaac 2520 tctggtgcca acttagacaa tactctttaa agcactcctt tttagttatc accacctgtc 2580 cagctccctt attaggtcga gacattttaa ctaaattatc tgcttccctg actattcctg 2640 ggctacagcc acacctcatt gccacctttt accccagttc aaagcctcct tcacatcctc 2700 tccttgtatc tccccacttt aaaccacaag tataggacac ctctacatcc tccttagcga 2760 cccatcatgc acctcttacc atctcattaa aacctaatca cccttacccc actcaatgcc 2820 aatatcccat cccacagcat gctttaaaag gattaaagcc tgttatcatt cgcctgttac 2880 agcatggcct tttaaagcct ataaactctc cttacaattc ccccatttta cctgtccaaa 2940 aaccggacaa gccttacagg ttagttcagg atctgagcct tatcaaccaa attgttttgc 3000 ctatccaccc catggtacca accccatata ctctcctatc ctaaatacct ccctccacaa 3060 acccattatt ttattctgga tctcaaacat gctttcttta ctattccttt gcaccattca 3120 ccccagcctc tcttcgcttt cacttaactg accctgacac ccatcaggct cagcaaatta 3180 cctgggctgt actgccacaa ggcttcacag acagccccca ttacttcagt caagcccaaa 3240 tttcttcctc atctgttacc tatcactgca taattctcat aaaaacacat gtgctctccc 3300 tgctgatggt gtccagctaa tctcccaaat cccaatccct tctacaacat agcaactcct 3360 ttccttccta ggcatggtta gtgtggtcag aattcttaca caagagccag gactgcaccc 3420 tgtagccttt ctgtccaaac aacttaacct cattgtttta gcttagccct catgtctgtg 3480 tgcagtggct gccactgcct taataatttt agaggccctc aaaatcacaa actatgctca 3540 actcactcta cagttctcat aacttccaaa atctattttc ttcctcacac ctgatgcata 3600 tactttctgc cccactccac taactctcag aaagtcgaac tcattgcctt aactcgagca 3660 ctcactcttg caaaaggact acacatcaat atttgtactg actctaaata tgccttccat 3720 atcttgcacc accatgctgt tatataggct gaaagagatt tcctcaccac ctttgcatag 3780 tggcaaagtc ctccatcatt aatgcctctt taataaacac tctactcaag gctgctttac 3840 ttccaaagga aaccgaagtc attcactgca agggccatca aaaggcattg ctctaagcaa 3900 ggcttatgct gataaagtgg ctagacaagc agctagcttc caacttctgt ccctcacggc 3960 cagtttttct ccttcacatc ggtcactccc acctactccc ctgctgaaac ttccacctat 4020 caatctcttc ctacacaagg caaatggttc ttaggccaag gaaaatatct ccttccagcc 4080 tcacaggccc attctattct gtcatcattt cataacctct tccatgtagg aagctgctag 4140 cctgtctctt agaacctctc atttcctttc catcctggaa atttattctc aaggaaatca 4200 cttctcagtg ttccatctgc tagtctacta ccactcaggg attgttcagg cctcctccct 4260 ttcctataca tcaagctcgg ggatttgccc ctgcctggga ctggcaaatt gactttactc 4320 acatgccctg agtcagaaaa ctaaaatctg gatagacact ttcactggat gggtagaggc 4380 ctttcctaca gggtctgaga aggccaccac agtcatttct tcccttctgt cagacataat 4440 tctttggttt ggccttccca cctctataca gtctgagagc agactgacct ttattagtca 4500 aatcagccaa gcattttttc aggctcttgg tattcagtga aacctttata tcccttacgg 4560 tctgcagtct tcaggaaagg tagaacgaac taatggtctt ttaaaaacac acctcaccaa 4620 gctcaaccac caacttaaaa aggactggac aatactttta ccactttccc ttctcagaat 4680 tcaggcctgt cctcagaatg ctacagggta cagcccattc gagctcctgt atagacactc 4740 ctttttattg gccccagtct cattccagac accagaccaa cttagactgt gccccaaaaa 4800 acttgtcttc cctactatct tctgtctagt cacactccta ttcaccgttc tcaactactc 4860 atacatgccc tgctcttgtt tacactgcca gtttacactg tttcttcaag ccatcacagc 4920 tgatatctcc tggtgctatc ctcaaactgc cactcttaac tcttaaagta aataaataat 4980 ctttgctggc aggactatgc tgaatctcct taggcactct ctaattagat gtcctgggtc 5040 ctcccggttc tcagaccttt aatacctgtt tttctccttc tcttattccg tttagttttt 5100 caattcagac aaaaccttat ccaggccatc atcaataatt ctaaatgact aatgtttctt 5160 ctaacaaccc cacaatatga ccccttacca caaaatcttc cttcacctta atctctccca 5220 ctctaggttc ccacgccgcc ccaatcccac tcaaagcggc cctgagaaac attgcccatt 5280 atctctccat accacctgca aaaattttta ccgtccaaca ctttaccatg atttcatttt 5340 atttttctta ttaatataag aagacaggaa tgtcaggccc ctgagccgaa gctaagccat 5400 catatcccct gtgacctgca cgtacacatc cagatggcca gttcctgcct taactgatga 5460 cattccacca caaaagaagt gaaaatggcc tgttcctgcc ttaactgatg acattatctt 5520 gtgaaattcc ttctcctggc tcattctggc tcaaaagctc ccctactgag caccttgtga 5580 cccccactcc tgcctgtcag agaacaaccc ccctttgact gtaattttcc tttacctact 5640 caaatcttat aaaatagccc caccccatct cccttctctg actctctttt cagactcaac 5700 ccgcctgtgc ccaggtgatt aaaaagtgta ttgctcacac aaagtctgtt tggtggtctc 5760 ttcacacaga cgcgagtgaa a 5781 <210> 60 <211> 2376 <212> DNA <213> Homo sapiens <400> 60 acaacttgac cttactgttt taggctggcc atcatgtccc cgtgcagcag ctgccgctgc 60 cctaacactt ttagaggccc tcaaaatcac aaactatgct caactcactc tctatagttc 120 tcataacttc caaaatctat tttcttcctc acacctgatg catatacttt ctgctccccg 180 gctccttcag ctgtactcac tctttgttga gtctcccaca gttaccattg ttcctggccc 240 ggacttcaat ccagcctccc acactattcc ggatacatct gactcccatg actgtatctc 300 tctgatccac atgacattca ctccctttct ccatgtttcc ttctttcctg ttcctcaccc 360 tgatcacact tggtttattg atggcagttc caccaggcct aatcgccact caccagcaaa 420 ggcaggctat gctatagtat cttccacatc tatcactgag gctaccgctc tgcccccctc 480 cattacctct cagcaagctg aactcactgc cttaacttga gccctcactc ttgcaaaggg 540 actacccatc aatatttata ctgactctaa atatgccttc catatcctgc accaccatgc 600 tgttatatag gcagaaagaa gtttcctcac tatgcaagag tcctccatca ataatgcctc 660 tttaataaga actcttctca aggctgcttt acttccaaag aaagccggag tcattcactg 720 caaaggccat caaaaggctt cagatcccat tgctctggac aacgcctatg ctgataagat 780 agctaaaaaa gcagctagcg ttccaacttc tatccctcag ggcagttttc ctccttctca 840 tctggccact cccacctact ccctcgctga aacttccacc catctcttcc cacacaaagc 900 aaatggttct tggaccaaag aaaaatctcc ttccagtctc acaggcccat tctattcgtc 960 atttcataac ctcttccatg taggttgcaa gccgctagcc cgcctcttag aacccgctag 1020 cccacctctt agaacctctc atttcctttc catcgcaaaa atctatcctc aaggaaatca 1080 cttttcagtg ttccatctgc tattctacta ctcctcaaga atttctcagg ccccctccct 1140 tccccacaca tcaagctcgg ggatttgccc cgcccaggac tggcaaattg actttactca 1200 catgcctcga gtcaggaaac taaaatacct cttggtctgg gtagacactt tcactggatg 1260 ggtagaggcc tttcccacag ggtctaagaa ggccaccgtg gtcatttatt cccttctgtc 1320 agacatagtt cctcggtttg gccttctcac ctctatacag tccgataacg gaccggcctt 1380 tactagtcaa atcacccaag cagtttctca ggctgttggt attcagtggc acctggtttt 1440 tcctcaaact gccaccctta agtctctctt taagtggata gaagatcttc agtggcaagg 1500 taccctccaa tactttcacc ctgatgaagt cctattcttt acttttatac ttactcttat 1560 tctcattccc gttcttatgc caccctctac ctctccccag ctatctctat cacactatca 1620 atctcagtta ctctctccta gccgtttcta atccttcttt aacaaacaat tgctggcttt 1680 gcatttctct ttcttccaaa atcacaaagg tctcgactta ctgctaaaaa aaaaaaaaag 1740 gggactctat atttttaaat gaagagtgct atttttacct aaatcaatct ggcctggtat 1800 atgacaacat taaaaaaaac tcaaagatag agcctaaaag cttgccaacc aagcaagtaa 1860 ttacactaac cccccttgga cactctaatt agatgtcctg ggtcctccca attcttagtc 1920 cttttatacc tgtttttctc cttctcttat tcagaccttg tgtcttccat ttagtttctc 1980 aattcatcca aaaccatatc caggccatca ccaatcattc tatacgacaa atgtttcttc 2040 taacaacccg acaattatca ccccttacca caaaatcttc cttcagcttc atctctccca 2100 cactaggttt ccatgttgcc ccagtcctgc tcaaagcagc cctgagaaac attgcccatt 2160 atctctccat accacccccc aaaattttcc ccaccccaac actttaccac tattttattt 2220 ttcttattaa tataagaaga caggaatgtc aggcctctga gcccaagcta agccatcata 2280 tccccagtga cctgcacgta tacatccaga tggcctgaag caactgaaga tacacaaaag 2340 aagtgaaaat agccttaact gataacattc caccat 2376 <210> 61 <211> 2178 <212> DNA <213> Homo sapiens <400> 61 tgactctctt tttggactca gctcgcctgc acccaggtga ttaaaaagct ttattgctca 60 cacaaagcct gtttggtggt ctcttcacat ggacgtgagt gaaatttggt gccatgactc 120 agatcggggg acctcccttg ggagatcaat cccctgtcct cctgctcttt gttctgtgag 180 aaagatccac ctacgacctc tggtccccag accaactagc ccaaggaaca tctcaccaat 240 tttaaatcca gtaagtggcc tctttttact ctcttctaca acctctctca ctatccctca 300 acctctttct cctttaaatc ttggcgtcac acttcagtct ctcccttctc ttaatttcag 360 ttcctttcct tttctggtag agatgaagga gacacgtttt atccgtggac ccaaaactcc 420 ggcgccagtc aaggactggg gaagacagtc ttctcttggt gtttaatcac gcggagacgc 480 ctgcctgatt attcacctaa gtttcagagg tgtctgacca tgcagggacg cctgccttgg 540 tccgtcaccc ttagcagcaa gtaccgcttt tctggggggc aagaaccccc caaccccttc 600 tctccgtgtc tctacccctt ctccactttt ctggcgggca agaacccccc aaccccttct 660 ccttcaccct tagcagcaag taccactttt ctagggggca agaacccctc aaccccttct 720 ccttcactct tagtggcaag tactgctttt ctagggggca ggaacccccc gaccccttct 780 ctctgtcttt accccttctc tgcttttctg ggggtcaaga accccccacc ccttctctcc 840 gtgtctctac tctctctttt ctctgggctt gcctccttca ctatgggcaa gcttccaccc 900 tccattcccc cttcttctcc cttagcctgt gttcttaaaa acctaaaacc tcttcaacaa 960 acacctgacc taaaacctaa atgccttatt tccttctgca atgccacttg acccaataca 1020 aactcaacag tggttccaaa tagcgagaaa atagcacttt caatttttcc atcctatgag 1080 atctaaataa ttcttgccgt aaaataggca aacggtctga ggtgcctgac gtccaggcat 1140 tcttttacac gtcggtccct ccctagtttc tgttcccaat gcaacttgtc ccaaatcttc 1200 cttctttctc tcccgcctgt ccccttagtc ccaaccccaa gcatcgctga gtctttctaa 1260 tattcctttt ctacagaccc atctgacctc tcccctcctc gccaggctga gctaggtccc 1320 aattcttcct cagcctctgc tcctccaccc tattatcctt tttatcacct cccctcctca 1380 caccaggtcc ggctcacagt ttcgttctga gactagccct cccccacctg cccagcaatt 1440 tcctcttaaa aaggtggctg gagctaaagg cacaatcaag gttaatgctc ctttttcttt 1500 atcccaaatt agagagcatt taggctcttt ttcaacagat ataagaaccc agcccagttc 1560 atggctcatt tagcagcaac cctgagacgc tttacagccc tagaccctaa aaggtcaaaa 1620 ggacgtctta ttctcaatat acattttatt atccaatctg ctcccgacat taaataaaac 1680 tccaaaaatt aaattccagc cctcaaaccc cacaacagga cttaattaac ctcgccttca 1740 aggtgtacaa taatagagta gaggcagcca agtagcaaca tatttctgag ttgcaattcc 1800 ttgcctccac tgtgagacaa accccagcca catctccaca cacaaaaact tccaaatgcc 1860 taaaccacag tggccaggca ttccttcagg cccgcctccc ccagaagctt gctacaagtg 1920 ccagaaatct ggccaccagg ccaaggaatg cccacagccc agaattcctc ctaagctgcg 1980 tccaatctgt gcaggacccc actgaaaatc ggacagttca actcacctgg cagccactcg 2040 cagagcccct ggctctctga ctgactcctt cccagatctt ctcggcttag tggctgaaga 2100 ctgacactgc ccgatcacct tggaagcccc ctagaccatc acagacgccg agtttcaggt 2160 aactctcaca gtgaaagg 2178 <210> 62 <211> 3859 <212> DNA <213> Homo sapiens <400> 62 gtcaggcctc tgagcccaag ccaagccatc acatcccctg tgacttgcac gtatacatcc 60 agatggcctg aagtaactga agatccacaa aagaagtaaa aatagcctta actgatgaca 120 ttccaccatt gtgatttgtt cctgccccac cctaactgat caatgtactt tgtaatctcc 180 cccaccctta agaaggttct ttgtaattct ccccaccctt gagaatgtac tttgtgagag 240 ccacccctgc ccacaaaaca ttgctcttaa cttcactgcc tatcccaaaa cctataagaa 300 ctaatgacaa tccaccaccc tttgctgact ctctttttgg actcagccca cctgcaccca 360 ggtgaaatac acagctttat tcctcacaca aagcctgttt ggtggtctct tcacacggac 420 gcgcatgaaa tttggtgtcg tgactcggat caggggacct cccttggcag atcaatcccc 480 tgtcctcctg ctctttgctc catgagaaag atccacctat gacctcaggt cctcagacca 540 accagcccaa gaaacatctc accaatttca aatccggtaa gcggcctcct tttactctct 600 tctccaactt ccctcactat ccctcaacct ctttctcctt tcaatcttgg cgccacactt 660 caatctctcc cttctcttaa ttttaattcc tttcattttc tggtagagac aaaggagaca 720 cgttttatac gtggacccaa aactgtggtg ccggtcacag actgggaagg cagccttccc 780 ttggtgttta atcactgcag ggacgcctct ctgattattc acccacgttt caagggtgtc 840 agaccacgca gggacgcctg ccttggtcct tcacccttag cagcaagtcc cgcttttctg 900 gggaaagggc aagtaccgca accccttctc tccttgtctc tatcccttct ctgcttttct 960 ggggaaaggg caagtacccc aaccccttct ctccttgtct ctatcccttc tctgcttttc 1020 tgggagaggg gcaagtaccc ctcaacccct tctccttcac cctcagcggc aagtcccgct 1080 tttctggggg aggggcaagt accccaaccc cttctctcct tgtctctacc ccttctctgc 1140 ttttctgggg aaagggcaag taccccaacc ccttctctcc ttgtctctac cccttctctg 1200 cttttctggg gaaagggcaa gtaccccaac cccttctctc cttgtctcta tcccttctct 1260 gcttttctgg gagaggggca agtacccctc aaccccttct ccttcaccct cagcggcaag 1320 tcccgctttt ctgggggagg ggcaagtacc cctcaacccc ttctccttca cgcttagcgg 1380 caagtcccgc ttttctaggg ggcaagaacc cccaatccct tatttccaca ccccgacctc 1440 ttatctctgt gccccaatcc cttatttctg tgccccaacc ccccttccca cttttctgga 1500 gggtaagaac cccaaacccc ttccctccat gtctctacac tctcttttct ctgggtttgc 1560 ctccttcact atgggcaacc ttccaccctc cattcctcct tcttctccct tagcctgtgt 1620 cctcaagaac ttaaaacctc ttcaactcac acctgaccta aaacctaaat gccttatttt 1680 cttctgcaac actgcttggc cccaatacaa acttgacaat ggctctaaat ggccagaaaa 1740 cagcactttc aatttctcca tcctacaaga cctaaataat ttttgtcaaa aaatgggcaa 1800 atggtctgag gtgccttatg tccaggcatt tttcacactt cattccctcc ctagcctctg 1860 ttcccaatgc gattcctccc agatcctcct tctttccctc ccgcctgtcc cctcagtctc 1920 aaccccaagt gtcgctgagt ctttccagtc ttccttttct acagacccat ctgacctttc 1980 ccctcctccc caggctgctc atcagcaggc tgagctaagt cccaattctt cctcagcctc 2040 cactcctcca ccctataatc cttctatcac ctcccctcct cacacctggt ccggcttaca 2100 gtttagttcc gtgactagct cttccccacc tgcccagcaa tttactctta aaaaggtggc 2160 tggagctaaa ggcatagtca aggttaatgc tcctttttct ttatcccaaa tcagatagcg 2220 tttaggctct ttttcatcaa atataaaaac ccagcccagt tcatggctcg ttcggcagca 2280 accctgagac actttacagc cctagaccct aaaaggtcaa aaggctgtct tattctcaaa 2340 atacatttta ttacccaatc tgctcccaac attaaataaa actccaaaaa ttaaattcca 2400 gccctcaaac cccacaacag gatttaatta acctcgcctt caagatgtac aataatagaa 2460 aaaagttgca attccttgtc tccactgtga gacaaacccc agccacatct ccagcacaca 2520 agaacttcca aacacctgaa ccgcagctgc caggcgttcc tccagaacct cctccccagg 2580 agcttgctac aagtgccaaa aatctggcca ccaagccaag gaatgccgac agcccaggat 2640 tcctcctaag ctgtgtcccg tctgtgcggg accccactga aaatcggact gttcaactca 2700 cctggtagcc acttccagag cccctggaac tctggcccaa ggctctctga ttccttccca 2760 gatcttctta gcttagtggc tgaagactga cgctgcccaa tcgcctcgga agcgccgtag 2820 accatcacgg atgccgagct tcaggtaact ctcacagtgg aaggtaagtc tgtccccttc 2880 ttaatcaata cggaggctac ccactctata ttaccttctt ttcaagggcc tgtttccctt 2940 gcctccataa ctgttatggg tattgatggc caggcttcta aacctcttaa aactccccaa 3000 ctctggtgcc aacttagaca acactgtttt atgcactctt ttttagttat ccccacctgc 3060 ccagttccct tattaggctg agacacttta actaaattat ctgcttccct gactattcct 3120 ggactacagc cacatctcat tgccaccctt cttcccaatc caaagcctcc ttcgcgtctt 3180 cctctcgtat ccccccacct taacccacaa gtatgggaca tctctactcc ttccctggca 3240 actgatcaca tgcccattac catcccatta aaacctaatc acccttaccc cactcaacgc 3300 caatatccca tcccacagca cgctttaaaa ggattaaagc ctgttatcac tcgcctgcta 3360 cagcatgggc ttctaaaacc tataaactct ccttaccatt cccccatttt acctgtccta 3420 aaaccagaca aggcttacaa gttagttcag aatctgcacc ttatcaacca aattgttttc 3480 ctatccaccc cgtggtgcca aacccatata ctctcctatc ctcaatacct ccctctacta 3540 cccattattc tgttctggat ctcaaacatg ctttctttac tgttcctttg cacccttcat 3600 cccagcctct ctttgccttc acttagactg accctgacac ccattagact cagcaaatta 3660 cctgggctgt actgccgcaa ggcttcagag acagtcccca ttacttcagt caagcccaaa 3720 tttcaacctc atctgttacc tatctcagca taattctcat aaaaacacat gtgctctctc 3780 tgcttatcgt gtcggattaa tctcccaaac ctcaatctct tacaaaagaa caactccttt 3840 ccttcctagg cgtggttag 3859 <210> 63 <211> 5863 <212> DNA <213> Homo sapiens <400> 63 gtcaggcctc tgagcccaaa ctaagccatc atatcccctg tgacctgcac gtacacatcc 60 agatggcagg ttcctgcctt aactaatgac attccaccac aaaagaaatg aaaatggcct 120 gttcctgcct taactgatga cattatcttg tgaaattcct tctcctggct catcctggct 180 caaaaacttc cctactgagc accttgtgac cccccactcc tgcccgccag agaaccccct 240 tttgactgta attttccttt acctacccaa atcttataaa atggccccac ccctatctcc 300 cttcgctgac tctcttttca gacaaagccc acctgcaccc aggtgaaata aacagccttg 360 ttgctcacac aaagtctgtt tggtggtctc ttcacacgga catgcatgaa atttggtgct 420 gtgactcgga tcgggggacc tcccttggga gatcaaaccc ctgtcctcct gctctttgct 480 ctgtgaaaaa gatccaccta ggacctcggg tcctcagacc caccagccca aggaacatct 540 caccaatttg aagttggata agcagactct tcttattctc ttctcccacc tctctcacta 600 tccctcaacc actttctcct ttcaatcttg gcgtcaccct tcaatctctc ccttctctta 660 atttcagttc ctttcctttt ctggtagaga acggagacgc gttttatctg tggacccaaa 720 actccggcgc cggtcacgga cttaggaagg cagccttccc ttggtgttta atcattgcag 780 ggacgcctct ctgattattc acccatgttt cagaggtgtc tgaccatgca gggatgcctg 840 ccttggtcct tcacccttag cagcaagtcc cgcttttcta ggggaggggc aagaactcca 900 accccttctc tccatgtctc taccccttct ctgcttttct gggaggcaag aaacccctga 960 taccttattt ctgtgccccg acctcttatc tctgtgcctc gatcccttat ttccacaccc 1020 ccacctctta tctctgtgcc ccatccctta tttccactcc ccgacctcct atctctgctc 1080 cccaatccct tatttccatg ccccgacccc tttcccactt ttctggaggg taagaacccc 1140 cgaacccctt ccctctgtgt ctctactctc tcttttttct gggcttgcgt ccttcactat 1200 gggcaacatt ccaccctcca ttcctccttc ttctccctta gcctgtgttc tcaaaaactt 1260 aaaatctctt caactcacat ctgacctaaa acctaaatgc cttatcttct tctgcaacac 1320 cgcttggccc caatacaaac ttgacaatgg ctctaaatgg ccataaaatt gcactttcaa 1380 tgtttccatc ctacaagatc taaataattc ttgccgtaaa atgggcgaat ggtctgaggt 1440 gcctgacgtc caggtattct ttcacacatc ggtccctctc tagtctctgt tcccaatgca 1500 actcatccca aatcttccat ttttccctcc cacctgtccc ctcagtccca atcccaagcg 1560 tcgctgagtc tttctaatct tcctttgtac agacacatct gacctcttcc ctcctcgcca 1620 ggccaagcta ggtcccaatt cttcctcagc ctctgctcct ccaccctata atccttttat 1680 cacctcccct cctcacaccc agtctggctt acagtttcct tccatgacta gccctccccc 1740 acctgcccag caatttcctc ttaaaaaggt ggctggagct aaaggcatag tcaaggttaa 1800 tgttcctttt tctttatacc aaatcagagc acatttaggc tctttttcat caaatataaa 1860 aacccagccc agttcatggc tcatttggca gcaaccatga gatgctttac agccctagac 1920 cctaaaatgt caaaaggctg tcttattctc aatatacatt ttattaccca atctgctccc 1980 gacattaaat aaaactccaa aaattaaatt ccagccctca aaccccacaa caggacttaa 2040 ttaacctcat cttcaaggtt tacaataata gagtagaggc tgccaagtag caacatattt 2100 ctgaattgca attccttacc tccactgtga gacaaacccc agccacatct ccagcacaca 2160 agaacttcca aacgcctaaa ccgcagtggc caggtgttcc tccaggcccg cctcccccag 2220 gagcttgcca caaatgccag aaatgtggcc accaggccaa ggaatgcccg cagcctggga 2280 ttcctcctaa gctgcatccc atctgtgtgg gaccccactg aaaattggac tgttcaactc 2340 acctggcagc cactctcaga gcccctggaa ctgtggccca aggctctctg actccttccc 2400 agatcttctc ggcttagtgg ctgaagactg atcctgccca atcgcctcgg aagcccccta 2460 gaacatcacc gacgctgagc ttcaggtaac tctcacagtg gagggtaagt ccgtcccctt 2520 cttagtcaat acggaggcta cccactccac gttaccttct tttcaaggcc tgtttccctt 2580 gcctccataa cttgtgggta ttgacggcca ggctactaaa cctcttaaaa ctccccaact 2640 ctggtgccaa cttagacaat actcttttaa gcactccttt ttagttatcc ccacctgccc 2700 agttccctta ttaggctgag acacttgaac taaattatct gcttccctga ctattcctgg 2760 gctacagcca cacctcactg ccaccttttc ccccagttca aagcctcctt cacatcctcc 2820 ccttgtatct ccccacctta acccataagt ataagacacc tctattccct ccttagtgac 2880 cgatcatgaa ccccttacca tcccattaaa acctaatcac tcttacctgg ctcaatgcca 2940 atatcccatc ccacagcatg ctttaaaatg attaaagtct gttatcactc gcctgttaca 3000 gcatggcctt ttaaagccta taaactctcc ttacaattcc cccattttac ctgtcctaga 3060 accagagaag ccttacaggt tagttcagga tctgagcctt atcaaccaaa ttgttttgcc 3120 tatccaccct gtggtgccca acccatatac tttcctatcc tcaatacctc cctccacaac 3180 ccattatttt gttctggatc tcaaacatgc tttctttact atccctttgc acccttcatc 3240 ccagcctctc ttcgctttca cttagactga ccctcacacc catcaggctc agcaaattac 3300 ctgggctgta ctgccagaag ccttcacaaa tagccccaat tacttcagtc aagcccaaat 3360 ttcatcctca tctgttacct atctcggcat aattctcata aaaacacacg tgctctccct 3420 gctgatcgtg tccaactaat ctcccaaacc tcaatccctt ctacagaaca acaactcctt 3480 tccttcccag acatggttag atactttcaa ctttagatat ctgattttgc catcgtaaca 3540 aaaccattat ataaactcac aaaaggaaac ctagctgacc ccatagatcc tgaatccttt 3600 acccactcct ctttccgttc cttgaagaca gctttagaga ctgccctcac cctagctctg 3660 actcatccca atccttttca ttacacacag ctgaagtgca gggctgtgca gtcagaattc 3720 ttacacaagg accaggattg catcctgtag ccttttggtc caaacaactt gaccatactg 3780 ttttaggctg gtcatcatgt ctccgtgcag tggctgctgc cgccctaata cttttagagg 3840 ccctcaaaat cacaaactat gctcaactca ctctctacag ttctcataac ttccaaaatc 3900 tattttcttc ctcacacctg acacatatac tccctggctc cttcagctgt actcactctt 3960 tgttgagtct cccacaatta ccattcttcc tggcgcagac ttcaatccag cctcccacat 4020 tattcctgat accacacttg actcccatga ctgtatctct ctgatccacc tgacattcac 4080 cccatttccc catatttcct tatttcctgt tcctcaccct gatcacgctt gatttattga 4140 tggcggttcc accaggccta atcgccacac gccagcagag gcaggctatg ctatagtaaa 4200 agccaccagc ccgcctctta gaatctctca tttcctttcc atcttggaaa tctgtcctca 4260 aggaaataat ttctcagtgt tccatctgct attctactac tcctcaggga ttattcgggc 4320 cccctccctt ccccacacat caagctcggg gatttgcccc cgcccaggac tggcaaattg 4380 gctttactca acatgcccca agtcagaaaa ctaacatacc tcttagtctg ggtagacact 4440 ttcactggat aggtagaggt ctttcccaca gggtctgaga aggtcaccgc ggtcatttct 4500 tcccttctgt cagacataat tcttcggttt ggccttccca cctctatata gtccgatagc 4560 agaccggcct ttattagtca aatcagccac gcagtttttc gctcttagta tccagtgaaa 4620 cctttatatc ccttacggtc ctcagtcttc aggaaaagta gaacggacta aaggtctttt 4680 aaaaacacac ctcaccaagc tcagccacca acttaaaagg actggacgta cttttaccac 4740 tttcccttct tagaattcag gcctgtcctt ggaatgctac agggtacagc ccatttgagc 4800 tcctgtatgg atgctccttt ttattaggcc ccagtctcat tccagacacc agactaactt 4860 agactgtgcc ccaaaaaact tgtcatccct actatcttct ctctagtcat actcctattc 4920 accattctca actactcaca cgtgccctgc ttttgtttcc actgccgttt actctgtttc 4980 tccaagccat cacagctgat atctcctggt gctatcccca aaccgccact cttagctctt 5040 aaagtaaata aataatcttt gcgggcaagg ctgtgctgaa cctccttagg cactctctaa 5100 ttagatgtcc taggtcctcc caattcttag tcctttaata cctgtttttc tccttctctt 5160 actctgttta gtttttcaat tcatacaaaa ccgtacccag gccatcacta ataattctac 5220 acaacgaatg tttcttctaa caaccccaca gtatcacccc ttaccacaaa atcttccttc 5280 agcttaatct ctcccactct aggttcccac gacgccccta atcccactcg aagcagccct 5340 gagaagcatc gcccattatc tctccatacc atcccccaaa attttcgctg tcccgacact 5400 ttaccactat ttcgttttat ttttcttatt aatataagaa gacaggaatg tcagccctct 5460 gagctcaagc taagccatca tatccactgt gacctgcacg tacacatcca gatggcaggt 5520 tcctgcctta actgatgaca ttccaccaca aaagaaatga aaatggcctc ttcctgcctt 5580 aactgatgac attatcttgt gaaattcctt ctcctggctc atcctggctc aaaagctccc 5640 ctactgagca ccttgtgacc ccccaactcc tgcccgccag agaaaaaccc cctttgactg 5700 taagtttcct ttacctaccc aaatcttata aaacggcccc acccctatct cccttcactg 5760 actctccttt cagactcagc ccacctgcag ccaggtgaaa taaacagcct tgttgctcac 5820 acaatgcctg tttggtggtc tcttcacatg gacgcgcatg aaa 5863 <210> 64 <211> 757 <212> DNA <213> Homo sapiens <400> 64 gagagagggc tagctggatt tcctaggcca actaagaatc cctaagccta gctgggaagg 60 tgaccgcatc cacctttaaa cacggggctt gcaacttagc tcacacccga ccaatcagag 120 agctcactaa aatgctaatt aggcaaaaac agtaggtaaa gaaatagcca atcatctatg 180 gcctgagagg acagcgagag ggacaaggat cgggatataa acccaggcat tcaagccggc 240 aatggcaacc ccctttgggt cccctccctt tgtatgggag ctctgttttc actctatttc 300 actctattac atcttgcaac tgcgctcttc tggtctgtgt ttgttacagc tcgagctgag 360 ctttcgctcg ccatccacca ctgctgtttg ccaccattgc agacctacca ctgacttcca 420 tccctccaga tctggcaggg tgtccgctgt gctcctgatg cagccatgcg cccattgcca 480 ctcccgatcg ggctaaaggc ttgccattgt tccggtacgg ctaagtgcct gggtttgtcc 540 taatcgagct gaacactagt cactgggttc catggttctc ttccgtgacc cacgacttct 600 aatagagctg taacactcac tgcatggccc aagattccat tccttggaat ctgtgaggcc 660 aagaacccca ggtcagagaa cacgaggctt gccaccatct tggaagtggc ccaccactat 720 cttgggagct ctgggagcaa ggacccccag taacact 757 <210> 65 <211> 440 <212> DNA <213> Homo sapiens <400> 65 ccaggccatc gcatcccagg ccaggccatc gcatcccctg tgacttgcag gtatacatcc 60 agatggccta aagtaactga agatccacaa aagaagtaaa aacagcctta actgatgaca 120 ttccaccatt gtgatttgtt cctgccccac cctaactgat caatgtactt tgtaatcttc 180 cccaccctta agaaggttat ttgtaattct ccccaccctt gagaatgtac tttgtgagat 240 tcacccctgc ccaccagaga acaaccccct ttgactgtaa ttttccatta ccttcccaaa 300 tcctataaaa cggccccacc cctatctccc ttcgctgact ctcttttcgg actcagcccg 360 cctgcaccca ggtgaaatac acagccatgt tgctcacaca aagcctgttt ggtggtctct 420 tcacatggac gcacatgaaa 440 <210> 66 <211> 440 <212> DNA <213> Homo sapiens <400> 66 gtcaggcctc tgagcccagg ccaggccatc gcatcccctg tgacttgcac gtatacatcc 60 agatggcctg aagtaactga agatccacaa aagaagtaaa aacagcctta actgatgaca 120 ttccaccatt gtgatttgtt cctgccccac cctaactgat caatgtactt tataatctcc 180 cccaccctta agaaggttct ttgtaattct ccccagcctt gagaatgtac tttgtgagat 240 ccactcctgc ccacgagaga acaaccccct ttgactgtaa ttttccatta ccttcccaaa 300 tcctataaaa tggccccacc cctatctccc ttctctgact ctcttttggg actcagccct 360 cctgcaccca ggtgaaataa acagccatgt tgctcacaca aagcctgttt ggtggtctcc 420 tcacacggac gcacatgaaa 440 <210> 67 <211> 1177 <212> DNA <213> Homo sapiens <400> 67 aaaaagacag gaattgctca ctcagggagc tcggctcttg agacaggagt cttgctgatg 60 cccctggccg aataaacccc ttccttcttt aactcagtgt ctgaggagtt ttctgcgcct 120 cgtcctgcta catttcttgg ttccctgatg gggaagcgag gtgaatggcg gatggtcgag 180 gcagctcctt aggcggctta agcctgccgt gtggaacatc cctgcgggcg actctaacta 240 gcccgggcga cgcggatcct gagagtgctc cctggtaggc atttgcccca ggaggacgct 300 tcgccagagc agtgtgtggc aggcccctgt ggaggatcaa cacagtggct gaacaccagg 360 aaggaacggg cacttagagt ctggacatct aaaacttggt aagactagtc tttgaaactt 420 gcccactcca ggccaggtgt ggtgcctcag gcctgtaatc ccagcacttt gggaggccaa 480 ggcgggcgga tgacgaggtc aggagatcga gaccatcctg gctaacacgg tgaaacccct 540 tctctactaa aaatacaaaa aaattagctg ggcgtggtgg tgggtgcctg tagtccccac 600 cagagcgaga ctccgtctca aaaaaaaaaa aaaaagaaac ttgcccactg catttaagtg 660 gaagcgtggc ctgatcaccc atggtgtgcc tgtaccggca ctttagtttt tgtttttgac 720 ttgacttaga ttgcttaata ctctggtttt ggttttgacc taacttagat ttctagatac 780 tctgatttta gttttgattt tagtttggtg caaactgcga aagtgtgtgt gtgccctttt 840 tacctgttct ttgttttgtg gtgtgcgtgt ggtgtgagtg tggtgttttg tgtcgaagaa 900 gcataggtca ggcacaaata agcccaccct gctaggaact atgttgaaaa atttcaaaaa 960 agaatttaaa ggagactata gagtactatg acacgaggaa aacttaaaac tttgtgtaag 1020 atagactggc cagcattaga ggtaggttgg ccattagaaa aaagcctgga caggtccctt 1080 gtttcaaagg tatggcacaa agtaacctgt aagccaggga acccagacca gttcccgtac 1140 atagacactt ggttacagct agttttagac cccccgc 1177 <210> 68 <211> 879 <212> DNA <213> Homo sapiens <400> 68 aggcacccct acggaggaaa tctcaactgc acaaccccta ctgtgcccca attcagcagg 60 aagcagttag agcggtggtc aaacctcccc aatagcactt gggttttcct gttgagaggg 120 ggtactgaga gacaggacta gttggatttc ctaggctggc taagaatccc taagcctagc 180 tgggaaattg accacgtcca cctttaaaca cggggcttgc aatttagctc acacccgacc 240 aatcaggtag taaagagagc tcactaaaat gctaattagg gaaaaacagg aggtaaagaa 300 gtagccaatc atctatcgcc tgagagcaca acaggaggga caatgatcag gatataaacc 360 caggcattca agccagcggt ggctaccctc tttgggtccc ctccctttgt atggaagctc 420 tgttttcact ctattaaatc ttgcaattgc acacttttct ggtacgtgtg tgtcacagct 480 caagctgagc tttcgctcac cgtccaccac tgctgtctgc cgctgtcaca gacccacagc 540 tgacttccat ccctctggat ccagcgaggc gcccattgct gctcctgatc gggctaaagg 600 cttgcccttg ttcctgcagg gctaagtgcc caggttcgtc ctaatctagc taaacactag 660 tcactgggtt ccacgattct cttccatgac ccacagcttc taatagagct ataacactcg 720 ccgcttggcc caagattcca ttccttggaa tccatgaggc caagaacccc aggtcagaga 780 acacaagact tgccaccatc tcggaagtgg cccgtcacca tcttggaagc gacctgccac 840 catcttggga acttggggag caaggacccc cagtaacat 879 <210> 69 <211> 3642 <212> DNA <213> Homo sapiens <400> 69 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac gtataagccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa tatgccctgc cccaccttaa 120 ctgatgacat tccactacaa aagaagtgaa aatggccggt ccttgcctta agtgatgaca 180 ttaccttgtg aaagtccttt tcctggctca tcctggctca aaaacctccc ccactgagca 240 cctttcgacc ccgactcctg cccgccagag aacaaacccc ctttgactgt aattttcctt 300 tacctaccca aatcctataa aacagcccca cccttatctc ccttcactga ctctcttttc 360 cgactcagcc tacctgcacc caggtgaaat aaacagccat gttgctcacg caaagcctgt 420 ttggtggtct cttcacacgg acgcgcatga aatttggtgc cgtgacttgg atcgggggac 480 ctcccttcgg agatcaatcc cctgtcctcc tgttctttgc tccatgagaa agatccacct 540 acgacctcag gtcctcagac tgaccagccc aagaaacatc tcaccaattt caaatccggt 600 aagcggcctc tttttactct cttctccaac ctccctcact atccctcaac ctctttctcc 660 tttcaatctt ggcgccacac ttcaatctct gccttctgtt aatttcaatt cctttcattt 720 tctggtagag acaaaggaga cactttttat ccgtggaccc aaaactccgg cgccagtcac 780 ggactaggaa ggcagccttc ccttggtgtt taatcattgc agggacacct ctctgattat 840 tcacccatgt ttcaaaggtg tcagaccact cagggacacc tgccttggtc cttcaccctt 900 agcggcaagt cctgcttttc tggggaaggg gcaagtaccc caactctttc tctccttgtc 960 tctacccctt ctctgctttt ctgggggagg ggcaagtacc cctcaacccc ttctccttca 1020 cccttagcag caagtcccgc ttttccagag gaggggcaag taccccaacc tcgtatctct 1080 gtgccccaat cccttatttc cacgccacaa cctcttatat ctctgcaccc cagtccctta 1140 tttccacacc ctgacttctt atctctgcac cccaatccct tatttccatg ccccgacccc 1200 ttatttctgt gccccgaccc cttatttcca tgccccgacc ccttatttct gcaccccatc 1260 ccttatttct gtgccgcaac ctcttatctc tgtgccccaa ccccttttcc cacttttcta 1320 gaaggtaaga acccccgaac cccttccctc catttctcta ctctctcttt tctctaggct 1380 tgcttccttc actataggca actttccacc ctccattcct ccttctactc ccttaacctg 1440 tgttctcaaa aacttaaaac ctcttcaact cacacctgac ctaaaaccta aatgtcttat 1500 tttcttctgc aatgctgctt gaccccaata caaactcgac agtagttcca aatagccaga 1560 aaacggcact ttcaattttt ccattctaca agatctaaat acttcttatc gtaaaatagg 1620 caaatggtct gaggtgactg acgtccaggc attttttaca catcagtccc ttcctagtct 1680 ctgtgcccag tgcaactcgt cccaaatctt ctttcccttc cgcctgtccc ctcagtccca 1740 accccatgca tcactgagtc tttctaatct tctttttcta cagacccatc tgacctctac 1800 cctcctcgcc aggccaagct aggtcccaat tcttccaccc tataatcttt ttattgcctc 1860 ccctcctcat acctggtccg gcttacagtt tccttccgtg actagccctc ccccacctgc 1920 ccagcaattt cctcttaaaa aggtggctgg agccaaaggc atagtcaagg ttaatgctcc 1980 tttctcttta tcccaaatca gatagcgttt aggctctttt tcatcaaata taaaaaccca 2040 gcccagttca tgtctcattc ggcagcaacc ctgcgacgct ttacagccct agaccctaaa 2100 aggtcaaaag gccatcttat tctcaatata cattttatta cccaatctgc tcctgacatt 2160 aaataaaact ccaaaaatta gaatctggcc ctcaaacctc acaacaggat ttaattaacc 2220 tcaccttcaa ggtgtacaat aatagaaaaa agttgcaatt ccttgcctcc actgtgagac 2280 aaaccccagc cacatctcca gcacacaaga aattccaaac acctgaacca cagcggccag 2340 gcattcctcc agaacctcct cccccaggag cttgctacaa gtgccagaaa tctgaccacc 2400 aggccaagga atgcctgcag cccaggattc ctcctaagcc gtgtcccatt tgtgcaggac 2460 cccactggaa atcggactgt tcaactcacc tggcagccac tcccggagcc cctggaactc 2520 tggcccaaga ctctctgact gactccttct cggcttagcg gctgaagact gacgctgccc 2580 ggtcgcctcg gaagccccgt agaccatcag ggacgccgag ctttgggtaa ctctcacagt 2640 ggaaggtaag cccgtcccct tcttaatcaa tacagaggct acccactcca cattaccttc 2700 ttttcaaggg tctgtttccc ttgcctccat aactgttcta ggtattgacg gccaggcttc 2760 taaacctctt aaaactcccc aaatctagtg ccaacttaga caatactctt ttaagcactc 2820 ctttttagtt atccccacct gcccagttcc cttattaggc tgagacactt taactaaatt 2880 atctgcttcc ctgactgttc ctggactaca gctgtatctc attgccgcct ttcttcccaa 2940 tccaaagctt cctttgcgtc ctcctcttgt atccccccac cttaacccac aagtataaga 3000 tacctctact ccctccttgg tgaccgatca tgcacccctt accgtgtcat taaaacctaa 3060 tcacccttac cccactaaat gccaatatcc catcccgcag cacgctttaa aaagattaaa 3120 gcctgttatc actggcctgc tacagcatgg ccttttaaag cctataaact ctccttataa 3180 ttcccccatt ttacccatcc taaaactgca caagtcttac agattagttc aggatctgca 3240 tcttatcaac caaactgttt tgcctatcca ccctgtggtg cccaagctgt acactctttt 3300 gtcctcaata ccttcctcca caactcacta ttccgtgctt gatcttaaag atgctttttt 3360 cactattccc ctgcacccct cgtcccagcc tctcttcgct ttcacttaga ctgaccctga 3420 cacccattag gctctgcaaa ttacctaggc tgtactgccg caaggcttca tagacagccc 3480 ccattacttc agtcaagccc aaatttcatc ctcatctgtt acctatctcg ccataattct 3540 cataaaaaca cacgtgctct ccctgctgat catgtccgat taatctccca aacctcaatc 3600 ccttacaaaa caacaactcc tttccttcct aggcatagtt ag 3642 <210> 70 <211> 5603 <212> DNA <213> Homo sapiens <400> 70 cctttgctga ctctcttttt ggactcagcc cacctacacc caggtgaaat aaacagcctt 60 gttgctcaca caaagcctgt ttggtggtct cttcacacag aagcatgaga catttggtgc 120 tgaagacccg ggtcagaggg actccttcgg gagaccagtc ccctgtcctc accctcactc 180 cgtgaagaga tccacctatg acgtcaggtc ctcagaccaa ccagcccaag gaatatctca 240 ccaatttcaa atcgggtaaa cagtcttttc actctcttct ccagcctctc tccctaccct 300 tcaatctccc tgtccttcca agtccagtta tttttcctct ctaatagaga caaacgagac 360 acattttatc catggaccca aaactctggc gccagtcacc aacttaggaa gacagcctac 420 ccttggtgtt taatcattgc agggtgtgcc tgcttgatta ttcacccaca ccccattggt 480 gtctgatcac cacggggatg cctgccttgg tcattcaccc acattccctt ggtggcaagt 540 caattgtggg gacacctgct ttggctgctc acccacattg cagcccagga ctgctcccca 600 ccccgcttct ccgtgtctct acccttctct ttaaacttgc ctcctttact atgggcaacc 660 ttccaccctc catttctcct tcttctccct tagcctgtgt tctcaagagc ttaaaacctc 720 ttcacctctt gcctgaccta aaatctaagc atcttatttt cttctccaac accgcttggc 780 cccaatacaa actcgacaat ggttctaaat ggccagaaaa tgacactttc gatttctcca 840 tcccacgaga cctagatact ttttgtcgaa aaaagggcaa atggtctgag gtgccttacg 900 tccaggcatt tttcacactt tgttccctcc ttagtctctg ttcccaatgc gactcatccc 960 aaatcctcct tctttccctc ccgcctgtcc cttcagtctc aaccccagtc gtcactgagt 1020 cttgtgaatc ttccttttct gctgacccat ctgacccctc acctcctccc cagactgctc 1080 ctcctcagct cgctccccgc caggctgaat caggctccaa ctcttcttca gcctctgctc 1140 cctcacccta taacccttct attaactccc cttcccacac ccggtctggt ttacagtttc 1200 attctgcgac tagctctccc cctcctgccc aacaatttcc tcttagagag gtggctggag 1260 ctgaaggcat agtcagagta catgtgcctt tttctctacc aaacgtttcc caaatcagcc 1320 agcgtttagg ctctttctca tcagacacca ataaatatat acaggaattc caatatctaa 1380 ctctgtccta cagtttaacc tggagagact taaatgtcag cctaacttct accctctccc 1440 cagatgaatg ggaaagagtc ttctctctag cccaatctca cgctgataat caccggcttc 1500 atgagccaga cctccaggaa ggcattagag cagttccctg agaagatccc ctatggaact 1560 atcaggcaga ttccccaggt atagctaggc gaaattacat ggtttcttgc ctagttgaag 1620 ggcttaaaaa ggcagctcac aaagctgtta attatgacaa acttaaagaa actacccaag 1680 gtaaagatga aaacccagcc cagttcatgg cctgcttagt tagcagaaat ccttagatgc 1740 tttaccgccc tagacccaga gggaccagaa ggtcacctta ttcttaatat gcattttatc 1800 acccagtcag ctcctgacat tagaaaaaag cttcaaaaat tggaatccgg ccttcaaacc 1860 ccacaacagg aattaatcaa cctcgccttc aaggtgtaca ataatagaga ggaggtggcc 1920 agacagcaac gcatttctga gttacagcta cttgcctccg ctgtaagaca acccacaacc 1980 acatctccag catacaaaaa aacttcagaa catccaagcc acagctccca gaggctcctt 2040 aaaaacatcc tcgtggacct tgtttcaaat gccaaaagcc tggccactgg gcctcagaat 2100 gcccacggcc cgggattcct cctgagccgt gccctgtctg tgcaggcccc cactggaggt 2160 cagactgtcc gactcacatt gctgctgctc ctgaagcccc tggagcccaa acccaatgtt 2220 ccctggccaa ctccttccag atctgatgct gccggatcac ctcggaagcc tcctggacca 2280 tcacagatgc tttgggtaac tctcacagtg gagggtaagt acatcccctt attaatcaat 2340 acggaggcaa cccactccac attaccttct tttcaagggt gtgtttccct tgcctccata 2400 actgttgtgg attatgacag ccaggcttct taacctctta aaactcccca actctggtgc 2460 caacttggac aattttcttt tatgcactcc tttttagtta tcctcacctg cccagctccc 2520 ttattggctc gagacatttt aactaaatta catgcttccc tgactattcc taggctacag 2580 ccatacctca ttaccgccct tttcccccag ttcaaagcct ccttcacatc ctctccttgt 2640 atctccccac cttaatccac ctctactccc tccttgagga tggatgatgc accccttacc 2700 atcccattaa aacctaatca cccttacccc gatcaatgcc agtatcccat cccaccgcat 2760 gctttaaaag gattaaagcc tgttatcact tatctgttgt agcatggcct tttaaagcct 2820 ataaactctc cttacaattc ccccatttta cctgtccaaa aactggacaa gccttacatt 2880 ttagttcagg atctgcgcct tatcaacaaa attgtcttgc ctatccaccc catggtgcca 2940 aacccatata ttctcctatc ctcaatacct ccctccacaa cccattattc tgttctagat 3000 aaacctagct gaccccataa atcctaaatc ctttccacac tcccctgtcc attccttaaa 3060 aaacagccct ggccgggcgc ggtggctcac gcctgtaatc ccagcacttt gggaggccga 3120 ggcgggcgga tcacgaggtc aggagatcga gaccatcccg gctaaaacgg tgaaaccccg 3180 tctctactaa aaatacaaaa aattagccgg gcgtagtggc gggcgcctgt agtcccagct 3240 actcgggagg ctgaggcagg agaatggcgt gaacccggga ggcggagctt gcagtgagcc 3300 gagatcccgc cactgcactc cagcctgggc gacagagcga gactccgtct caaaaaaaaa 3360 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaac agccctaaaa tctgctccca 3420 cactagttct ccctaactca tcccaacctt tttcattaca cacagccgaa gtgcagggct 3480 atgtggttgg aattcttaca caagagccag gaccacgccc tgtagccttt ctgtccaaat 3540 aacttgacct tactgtttta gcctagccct catgtctgcg tggggtggct gccactgcct 3600 taatactttt agagaccctc aaaatcacaa actatgctca actcactctc tacagttctc 3660 ataacttcca aaatctattt tcttcctcac acctgatgca tatactttct gccctcctcc 3720 actacctctc agcaagccaa actcattgcc ttaactcgag ccctcactct tgcaaaagga 3780 ctacgtatca atatttatac tgactctaaa tatgccttcc atatcctaca ccaccatgct 3840 gttttatggg ctgaaagagg tttcctcact actcgagggt cctccatcat taatgcctct 3900 ttaataaaaa ctcttcttaa ggccgcttta cttccaaagg aagctggagt cattcactgc 3960 aagggccatt aaaaggcatc acatcccatc gctcagggca acgtttatac tgataaggta 4020 gctaaagaag cagctagcct tccaacttct gtccctcacg gccagttttt ctccttctca 4080 ttggtcactc ccacctactc accgactgaa acttctacct atcaacctct tcccacacaa 4140 ggcaaatggt tcttggacca aggaaaatat ctccttccag cctcacaggc ccattctaat 4200 ctatcatcat ttcataactt cttccatgta ggttacaagc tgctagcccg cctcttagaa 4260 cctctcattt cctttccatc atggaaatct atccttaagg aaatcacttc tcagtgttcc 4320 atctgctatt ctactactcc tcagggattg ttcaggcccc ctctcttccc tacacatcaa 4380 gctcggggat ttgcccctgc ccaggactgg gaaattgact ttactcacat gccccgagtc 4440 agaaaactaa aatacctctt ggtctgggta gacactttca ctagatgggt agaggccttt 4500 cccacagggt ctgagaaggc caccacagtc atttcttccc ttttgtcaga cgtaattcct 4560 cagtttggcc ttcccaccta tatacagtcc aataacgggc ctgcctttat tagtcaaatc 4620 acccaagcag tttctcaggc tcttggtatt tagtggctcc tggttttacc tcaaatcgcc 4680 acccttaagc ctctcttgaa ttggatagaa gatcttcagt ggcaaggtac cctccaatac 4740 tttcaccctg atgaagtcct attctttatt tttatactca ctcttattct ggttcccgtt 4800 cttatgccac cttctacctc tccgcagcta tctccaccac actatcaaat tcactctctc 4860 ctagccgttt ctaatccttc tttaacaaac aattgctggc tttgcatttc actttcctcc 4920 aaaatcgctg aggccctgac ttactcactg ctaaaaaaaa gggggggact gtatatttgt 4980 aaatgaagag tgttgttttt acctaaatca atctggcctg gtatatgaca acataaaaaa 5040 aactcaagga tagagcccaa aaacttgcca accaagaaaa taattatgct gaaccccctt 5100 tgacactctg taattggacg tcctgggtgc tcccaattct tagtccttta atacctgttt 5160 ttctctttct cttatttgga ccttgtgtct ttcgtttagt ttctcaattc atacaaaacc 5220 acatccaggc catcaccaat aattctatac tacaaatgct ccttctaaca accccacaat 5280 atcacccctt accccaaaac ctttcttcag ttgggtctct cccactgtag gttcccacgc 5340 caccccaatc ccgcttgaag cagccctgag aaatcaccca ttatctctcc ataccacccc 5400 aaaaaatttt caccgcccca acactttacc actatttcat tttatttttc ttattaatat 5460 aagaagacag gaatgtcagg cctctgagcc caggctaagc catcataacc cctgtggcct 5520 gcatgcatac atccagatgg cctgaagcaa ctgaagatcc acaaaagaag tgaaaatagc 5580 cttaactgat aacattccac cat 5603 <210> 71 <211> 2123 <212> DNA <213> Homo sapiens <400> 71 tgactctctg tttggactca gcccacctgc acccaggtga aataaacagc catgttgctc 60 acacaaagcc tgtttggtgg tctcttcaca cggacgcaca tgaaatttgg tgtcgtgact 120 cggatcgggg gacctccctt gggagatcaa tcccctgtcc tcctgctctt tgctctgtga 180 gaaagatcca cctacgacct caggtcctca gaccgaccag cccaagaaac atctcaccaa 240 tttcaaatcc agtaagcggc ctctttttac tctcttctcc aacttccctc actatccctc 300 aacctctttc tcctttcaat cttggcgcta cacttcaatc tctcccttct cttaatttca 360 attcctttca ttttctggta gagacaaaag agacacgttt tatccgtgga cccaaaactc 420 cggcgccggt cacggactgg gaaggcagcc ttcccttggt gtttaatcat tgcagggacg 480 cctctgtgat tatacaccca cgtttcaagg gtgtcagacc acgcagggac acctgccttg 540 gtccttcacc cttagcggca agtcctgctt ttctggggaa ggggcaagta ccccaacccc 600 ttctctcctt gtctctaccc cttctctgcc tttcctgggg caggggcaag tacccctcaa 660 ccccttctcc ttcaccctta gaggcaagtc ccgctttcct aggggcaaga acctcccaat 720 cgcttatttc cgcaccccaa cctcttatct ctgtgcccca atcccttatt tccgtgcccc 780 aaccctttct ctgcttttct ggagggcaag aactccccac cccttctcca tgtctctact 840 cttttctctg ggcttgcctc cttcactatg ggtaggcttc caccttccat tcctccttgt 900 tctcccttag cctgtgttct caaaaactta aaacctcttc aactcacacc tgacctaaaa 960 cctaaatgcc ttattttctt ctgcaatgcc gcttgacccc aatacaaact cgacagtagt 1020 tccaaatagc tggaaaacgg cgctttcaat ttttccatcc tacaagatct aaataattct 1080 tgtcgtaaaa tgggcaaatg gtctgaggtg cctgacgtcc aggcattctt ttacacatca 1140 gtcccttcct agtctctgtg ccccgtgcaa ctcgtcccaa atcttccttc tttccctccc 1200 tcctgtcccc tcagtcccaa ccccaagcgg cgctgagtct ttctaatctt cctcttctac 1260 agacccatct gacctctccc ctccgcgcca gcccaagcta ggtcccaatt cttcctcagc 1320 ctccgcgcct cccccccctt catcccacac ctggtccgac ttacagtttc attctgtgac 1380 tagccctccc ccacctgccc agcaatttac tcttaaaaag gtggctggag ccaaaggcat 1440 agtcagggtt aatgctcctt tttctttatc ccaaatcaca tagcgtttag gctctttttc 1500 atcaaatata aaaacccagc ccagttcatg gctcgttcgg cagcaaccct gagacgcttt 1560 acagccctag accctaaaag gtcaaaaggc catcttattc tcaatataca ttttattacc 1620 cgatctgctc ccgacattaa ataaaactcc aaaaattaaa ttccggccct caaaccccac 1680 aacaggattt aattaacctt gccttcaagg tgtacaataa tagaaaaaag ttgcaattcc 1740 ttggctccac tgtgagacaa accccagcca catctccagc atacaagaac ttccaaatgc 1800 ctgaaccgca gcggctaggc gttcttctag aacctcctcc cccaggagct tgctacaagt 1860 gccagaaatc tgaccaccag ggcaaggaat gcctgcagcc caggattcct cctaagccgt 1920 gtcccatctg tgcgggaccc tactggaaat tagactgttc aactcacctg gcagccactc 1980 cccgagcccc tgcaactctg gcccaaggct ctctgactga ctccttctcg gcttagcggc 2040 tgaagactga tgctgcccga tcgcctcgga agccccatag gccatcacgg acgccgagct 2100 ttgagtaact ctcagagtgg aag 2123 <210> 72 <211> 5806 <212> DNA <213> Homo sapiens <400> 72 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgatttgcac atgtacgccc 60 agatgacctg aagtaactga agaatcacaa aagaagtgaa tatgccctgc cccaccttaa 120 ctgatgacat tccaccacaa aagaagtgta aatggccagt ccttgcctta agtgatgaca 180 ttaccttgtg aaagtccttt tcctggctca tcctggctca aaaagcaccc ccactgagca 240 ccttgcgacc cccactgctg cctgccagag aacaaccccc ctttgactaa ttttccttta 300 cctacccaga tcctataaaa tggccccacc cctatctccc ttcaccgact ctcttttcgg 360 actcagtccg cctgcacccg ggtgaaataa acagccatgt tgctcacaca aagcctgttt 420 ggtggtctct tcacacggac gtgcatgaaa tttggtgccg tgactcggat cgggggacct 480 cccttgggag atcaatcccc tgtcctcctg ttctttgctc cacgagaaag atccacctac 540 gacctcaggt cctcagactg accagcccaa ggaacatctc accaatttta aatcaggtaa 600 gcggcctctt cttactctct tctccaacct ctctcactgt ccctcaacca ctttcttctt 660 tccactcttc aatctctccc ttctcttaat ttcaattcct ttcattttct gggagagaca 720 aaggagacat gtttttatcc gtggacccaa aactccggcg ctggtcacgg actgggaagg 780 cagccttccc ctggtgtttt atcattgcag ggacgcctct ctgattattc acccacgttt 840 caaaggtgtc agaccacgca gggacgcctg ccttggtcct tcacccttag cagcaagtcc 900 cacttttctg ggaaaggggc aagtacctca accccttctc tccttgtctc taccccttct 960 ctgcttttct gggggagggg caagtacccc tcaacccctt ctccttcact cttagcggca 1020 agtcccgctt ttctagagga tgggcaagta ccccaacctc gtatctctgt gccccaatcc 1080 cttatttccg cgccccaacc tcttatatct ctgtgcccca atcccttatt tccatgctcg 1140 accccttatt tccgtgcccc taccccttat ttctgtgctt catcccttat ttccatgccc 1200 cgacctctta tctctgcgcc ccaacctctt ttcccacttt tctggaaggt aagaaccccc 1260 gaaccccttc cctcagtttc tctactctct cttttctcta ggcttgcttc cttcactata 1320 ggcaaccttc cacccttcat tcctccttct actcccttgg cctgtgttct caaaaactta 1380 aaacctcttc aactcacacc tgacctaaaa cctaaatgcc ttattttctt ctgcaatgct 1440 gcttgacccc aatacaaact cgacagtagt tccaaatagc cagaaaatgg cactttgaat 1500 ttttccatcc tgcaagatct aagtaattct tgtcgtaaaa tagccaaatg gtctgaggtg 1560 cctgacgtcc aggcattctt ttacacatca gtcccttcct agtctctgtg cccagtgcca 1620 ctcatcccaa atcttccttc tttccctccc gcctgtcccc tcagtaccaa ccccaagcat 1680 cgctgagtct ttctaatctt ccttttctac agatccatct gacctctccc ttcctcccca 1740 ggctgctcct cgccaggccg agctaggtcc caattcttcc tcagcctctg ctcctccacc 1800 ctataatctt ttcatcacct cccctcctca cacctggtct ggcttacagt ttcgttccat 1860 gactagccct ccccctcctg cccagcaatt tactcttaaa aaggtggctg gagccaaagg 1920 catagtcaac tttaatgctc ctttttcttt atcccaaatc agatagcgtt taggctcttt 1980 ttcatcaaat ataaaaatcc agcccagttc atgacttgtt tggcagcaac cctgagacac 2040 tttacagccc tagaccctaa aaggtcaaaa ggccgtctta ttctcaaaat acattttatt 2100 acccaatctg ctccagacat taaataaaac tccaaaaatt aaattccggc cctcaaaccc 2160 cacaacagga tttaattaac ctcgccttca aggtgtacaa taatagaaaa atgttgcaat 2220 tccttgcctc cactgtgaga caaaccccag ccacatctcc agcacacagg aacttccaaa 2280 tgcctgaacc gcagcggcca ggctcctcca gaacctcctc ccacaggagc ttgctacatg 2340 tgccagaaat ctggccactg ggccaaggaa tgcctgcagc ccgggattcc tcctaagccg 2400 tgtcccatct gtgtgggacc ccactgaaaa tcggactgtt caactcacct ggcagccact 2460 cccagagccc ctggaactct ggcccaaggc tgactgactc cttcccagat cttctcggct 2520 tagcggctga agactgacac tgcttgatcg cctcggaagc cccctagacc atcacagacg 2580 ccgagcttcc ggtaactctc acagtggaag gtaagcccgt ccccttctta atcaatacgg 2640 aggctaccca ctccacatta ccttcttttc aagggcctgt ttcccttgcc tccataactg 2700 ttgtgggtat tgacggccag gcttctaaac ctcttaaaac tccccaactc tggtgccaac 2760 ttagacaata ctcttttaag cactcctttt tagttatccc cacctgccca gttcccttat 2820 taggctgaga cactttaact aaattgtctg cttccctgac tattcctgga ctacagctat 2880 atctcattgc cgcccttctt cccaatccaa agcctccttt gcgtcctcct cttgtatccc 2940 cccaccttaa cccacaagta taagatacct ctactccctc cttggcgacc aatcatgcac 3000 ccgttaccat ctcattaaaa cctaatcacc cttaccccac tcaacgccaa tatcccatcc 3060 cgcagcatgc tttaaaaaga ttaaagcctg ttatcacttg cctgctacag catggccttt 3120 taaagcctat aaactctcct tacaattccc ccattttacc tgtcctaaaa ccggacgagc 3180 cttacaagtt agttcaggat ctgcgcctta tcaaccaaat tgttttgcct atccaccccg 3240 tagtgccaaa cccatatact ctcctatcct cagtacctgc ctctataacc tattattctg 3300 ttctagatct caaacatgct ttctttacta ttcctttgca cccttaatcc cagcctctct 3360 tcactttcac ttggactgac cctgacaccc atcaagctca gcaagttacc taggctgtac 3420 tgccgcaaag cttcacagac agcccctatt acttcaatca agcccaaatt tcttcctcat 3480 ctgttaccta tctcagcata attctcataa aaacacacgt gctctccctg ccaatcatgt 3540 ccgactaatc tctcaaaccc aagcaccttc tacaaaacaa caactccttt ccttcctagg 3600 catggttagc gtggtcagaa ttcttacaca agagccagga ccgcaccctg tagcctttct 3660 gtccaaacaa cttgacctta ctgttttagc ctagccctca tgtctgcgtg cagcggctcc 3720 cgctgcttta atacttttag aggccctcaa aatcacaaac tatgctcaac tcactctcta 3780 cagttctcat aacttccaaa atctattttc ttcctcatac ctgacgcaca tactttctgc 3840 tccccggctc cttcagctgt acccactctt tgttgagtct cccacaatta ccgttgttcc 3900 tggcccagac ttcaatccgg cctcccacgt tattcctgat accacacctg acccccatga 3960 ctgtatctct ctgatccatc tgacattcac cccatttccc caaatttcct tctttcctct 4020 tcctcaccct gatcacgctt gatttattgt tggcggttcc accaggccta atcaccacac 4080 accagcaaag gcaggttatg ctatagtaca agccactagc ctgcctctta gaacctctca 4140 tttcctttcc atcgtggaaa tcgatcctca aggaaataac ttctcagtgt tccatctgct 4200 attctagtac tcctcaggga ttattcaggc ccccttcctt ccctacacac caagctcaag 4260 gatttgcccc acccaggact ggcaaattag ctttactcaa catgccctga gtcagataac 4320 taaaatacct cttagtctag gtagatactt tcactggata ggtagaggcc tttcctacag 4380 ggtctgagaa ggccaccgca gtcatttctt cccttctgtc agacataatt cctcagttta 4440 gccttcccac ctcaatacag tctgataaca gacaagcatt tattagtcaa atcagccaag 4500 cagtttttca ggctcttagt attcagtgaa acctttatgt cccttatggt cctctgtctt 4560 caagaaaagt agaatggact aaaggtcttt taaaaacaca ctcagccacc aacttaaaaa 4620 ggactggaca atacttttac cactttccct tctcagaatt caggcctgtc ctcggaatgc 4680 tgcagggtac agcgcatttg agctcctgta tagacactcc tttttattag gccccagtct 4740 cattccagac accagaccaa cttacactgt gccgcaaaaa acttgtcatc cctactatct 4800 tctgtctagt catactccta ttcaccattc tcaactactc atacatgccc tgctcttgtt 4860 tacactgccg gtttacactg tttttccatg ccatcacagc tgatatctcc tggtgctatc 4920 cccaaactgc cactcttaac tcttgaagta aataaataat ctttgctggc aggactatgc 4980 tgaatctcct taggcactct ctaatcagat atcctgagtc gtcccaattc ttagaccttt 5040 tatacctgtt tttctccttc ctttattcca tttagtttct caattcatcc aaatccatat 5100 ctaggccatc accaatcatt ctatatgaca aatgtttctt ctaacatccc cacaatatca 5160 ccccttacca caaggcctcc cttcagctta atctctccca ctctaggttc ccacgtcacc 5220 cctaatcccg cttgaagcag ccctgagaaa catcgcccat tctctctcca taccaccacc 5280 caaaaatttt tgccgcccca acacttcaac actattttgt tttatttttc ttattaatgt 5340 aagaaggcag gaatgtcagg cctctgagcc caagccaagc catggcatcc cctgtgattt 5400 gcacatgtac gcccagatgg cctgaagtaa ctgaagaatc acaaaagaag tgaatatgcc 5460 ctgccccacc ttaactgatg acattccacc acaaaagaag tgtaaatggc cagtccttgc 5520 cttaagtgat gacattacct tgtgaaagtc cttttcctgg ctcatcctgg ctcaaaaagc 5580 acccccactg agcaccttgc gacccccact gctgcctgcc agagaacaac ccccctttga 5640 ctgtaatttt cctttaccta cccaaatcct ataaaacggc cccaccccta tctcccttca 5700 ctgactctct tttcggactc agtccgcctg cacccgggtg aaataaacag ccatgttgct 5760 cacacaaagc ctgtttggtg gtctgttcac acggacgtgc atgaaa 5806 <210> 73 <211> 5708 <212> DNA <213> Homo sapiens <400> 73 gtcaggcctc tgagcccaag ccaagtcatc gcatcccctg tgacttgcac atatacgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aatgccctgc cccgccttaa 120 ctgatgacat tccaccacaa aagaaatgaa aatggccggt ccttgcctta agtgatgaca 180 ttaccttgtg aaagtccttt tcctggctca tcctggctca aaaagctccc ccactcagta 240 ccttgtgact cccacttctg cctgccagag aacaacgccc ctttttcctt tacctaccca 300 aatcctataa aacggcccca cccctatctc ccttcactga ccctcttttc ggactcagcc 360 cacctgcacc caggtgaaat aaacagcctt gttgctcaca caaagcctgt ttggtggtgt 420 cttcacacgg acgcacatga aatttggtgt cgtgattcgg atcggaggac ctcccttggg 480 agatcaatcc cctgtcctcc ggctctttgc tccgtgaaaa agatccatct atgacctcgg 540 gtcctcagac ccaccagccc aaggaacatc tcaccgattt taaatcgggt aagcggcctc 600 ttcttactct cttctccaac ctctctcact ctccctcaac cactttctcc tttcaatctt 660 ggtgccaccc ttcaatctct cccttctctt aatttcaatt cctttccttt tctggtagag 720 acaggagaca cgttttatcc gtggacccaa aactctggcg ccggtcacgg acttgggaag 780 acagtcttcc cttggtgttt aatcacacgg ggacaactgc ctgattatta cccacgtttc 840 agaggtgtct gaccacgcgg ggacgcctgc cttggtcctt cacccttagc agcaagtacc 900 gcttttctgg ggggcaagaa ccccccaacc ccttctctcc atgtctctac cccttctcca 960 ctgttctggg ggacaagaac cccccaaccc cttctctctg tgtctctacc ccttctctgc 1020 ttttctgggg gcaagaaccc cccgatcctt tatttccaca ccccgctctg tgccccgatc 1080 ccttatttct gcaccccgac ttcttatctc tgtgccccaa ccccttattt ccatgccccg 1140 acccctttcc tgcttttctg gaaggtaaga acccctgaac cccttccctc catgtcttta 1200 ctctcccttt tctttaaact tgcctccttc actataggca accttccacc ctccattcct 1260 ccttcttctc ccttagcctg tgttcttaag aacttaaaac ctctcaactc tcacctgacc 1320 taaaacctaa atgccttatt ttcttctgca gtgctgcttg accaaaatac aaactcaaca 1380 gtggttccaa atagcaagaa aatggcactt tcaatttttc catcctacaa gatctaaata 1440 attcttgtcg taaaataggc aaatggtctg aggtgcctga cgtccaggca ttcttttaca 1500 catcagtccc tccctagtct ctgttcccaa ggcaactcgt cccaaatcct ccttctttcc 1560 ctcctgcctg tcccctcagt cacaactcca aatgtcgctg agtctttcta atcttccttt 1620 tctacagacc catctgacct cctcgccagg ccgagccagg tcccagttct tcttcagcct 1680 ctgctcccca ccctataatc cttttatcac ctccattcct cacaccgggt ccagcttaca 1740 gttttgttcc tcgactagtc ttcccccacc tgcccagcaa tttcctctta aaaaggtggc 1800 tggagctaaa ggcacagtca aggttaacgc tcctttttct ttatccgacc tctcccaaaa 1860 tcagttagca tttaggcttt ttttcatcaa atatgaaaaa cccagcccag ttcatggctc 1920 atttggcagc aaccctgaga cgctttacag ccctagaccc tgaaaggtca gaaggccgtc 1980 ttattctcaa tatgcatttt atttttttta cccaatctgc tcccaacatg aaataaagct 2040 ccaaaaatta aattccggcc ctcaaacccc acaacaggac ttaattaacc ccgccttcaa 2100 ggtgtgcaat aataaagtag aggcagccaa gtagcaatgt atttctgagt tgcaattcct 2160 tgcctccact gtgagacaaa ccccagccac atctccagca cacaagaact ccaaacgcct 2220 gaacctcctc ccccaggagc ttgccacaag tgccggaaat ctgaccactg ggccaaggaa 2280 tgcccacagc ccgggattcc tcctaagcca tgtcccatct gtgcgggacc ccactgaaaa 2340 ttggactgtt caactcacct ggcagccact tccagagccc ctggaactct ggcccaaggc 2400 tctccgactg actccttccc agatcttctc ggcttagcag ctgaagactg acgctgcccg 2460 atcgcctcgg aagcctacag gaccatcaca aatactctga gtaactctca cagtggaggg 2520 taagtccatc tccttcttag tcaatatgga ggctacccac tccacattac cttcttttca 2580 agggcctgtt tcccttgcct ccataactgt tgtgggtatt gacggccagg cttctaaacc 2640 tcttaaaact cccaaactct ggtgccaact tagacaatac tctttgaagc actccttttt 2700 agttatcccc acctgcccag ttcccttgtt aggctgagac actttaacta aattatctgc 2760 ttccctgact attcccggac tacagctgca tctcattgcc acccttctcc ccaacccaaa 2820 gcctcctttg catcttcttc tcatatcccc ccaccttaac ccacaagtat gggacatctc 2880 tactccttcc ctggcaactg atcacatgcc cattaccatc ccattaaagc ctaatcactc 2940 ttaccctgct caatgttaat atcccatccc acagcacgct ttaaaaggat taaagcctgt 3000 tatcactcac ttgctacagc atggcctttt aaagcctata tactctcctt accattcccc 3060 tatttcacct gtcctaaaac cagacaagtc ttataggtta gttcaggatc tgtgccttat 3120 caaccaaatt gttttgccta tccacccccg tggtgccaaa cccatatact ctcctatcct 3180 caatacctcc ttctacaacc cattattctt ttctggatct caaacatgct ttctttacta 3240 ttcctttgca cccttcatcc cagcctctct ttgctttcac ttggactgac cctgacaccc 3300 attaggctca gcaaattacc tgggctatac tgccgcaagg cttcacagac agcccccatt 3360 acttcagtca agcccaaatt tcatcctcat ctgttaccta tctcggcata attctcacaa 3420 aaacacacgt gctttccctg ctgattgtgt ctgactaatc tcccaaacct caatccctta 3480 caaaacaaca actcctttcc ttcctaggca tggttagtgt ggtcagaatt cttacacaag 3540 agccgggacc acaccctgta gcctttctgt ccaaacaact tgaccttact gttttagcct 3600 agccctcatg tctgcgtgca gcagctgcca ctgctctaat acttttagag gccctcaaaa 3660 tcacaaacta tgctcaactc actttctaca gttctcataa tttccaaaat ctattttctt 3720 cctcacacct gacacttata ctttctgctc ccccggctcc ttcagttgta cccactcttt 3780 gttgagtccc acaattacca ttgttctcgg cccggacttc aatccggtct cccacattat 3840 tccagatacc acacctgacc ctcatgactg catctctctg atccacctga cgttcacccc 3900 atttccccac atttccttct tccctgtttc tcaccctcat cacatttggt ttattgatgg 3960 cagttccacc aggcctaatc accactcacc agcaaaggca gactatgcta tagtactagc 4020 cactagcccg cctcttagaa cctctcattt cctttccatc gtggaaatct atcctcaagg 4080 aaataacttc tcagtgttcc atctgctatt ctactactct tcatggatta ttcaggcccc 4140 ctcccttccc tacacatcaa gctcggggat ttgcccccgc ctaggactgg caaattggct 4200 ttactcaata tgccccaagt cagaaaacta aaatacctct tagtctgggt ggacactttc 4260 actggatggg tagaggcctt tcctacagga tctgagaagg ccactgcggt catttcttcc 4320 cttctgtcag atataattcc tcagtttggc cttcccacct ctatacagtc tgataacgga 4380 ccagccttta ttagtcaaat cagccaagca gtttttcagg ctcttggtat tcagttaaac 4440 ctttatatcc cttacggtcc tcagtcttca ggaaaggtag aacggactaa tggtctttaa 4500 aaaacacacc tcaccaagct cagccaccaa cttaaaaagg actggacaat acttttacca 4560 ctttcccttc tcagaattca ggcctgtcct tggaatgcca cagggtacag cccgtttgag 4620 ctcctgtttg gacgctcctt tttattaggc cccagtctca ttccagacac caaaccaagt 4680 tggactgtgc cccaaaaaac ttgtcatccc tactatcttc tgtctagtca tactcctatt 4740 caccgttctc aacgactcat acatgccctg ctcttgttta cactgccggt ttacactgtt 4800 tctccaagcc atcacagctg atatctcctg gtgctatccc caaaccgcca ctcttaactc 4860 ttaaagtaaa taaataatct ttgctggcag gactatgctg aatctcctta ggcactctct 4920 aattagatgt cctgggtcct cccaattctt agacctttaa tacctgtttt tctccttctc 4980 ttattccatt tagtttttca attcatacaa aaccatatcc aggccatcac caataattct 5040 aaatgacaaa tgtttcttct aacaacccca caatatcacc ccttaccaca agacctccct 5100 tcagcttaat ccctcccact ctaggttccc acgccgcccc taatcccgct tgaagcagcc 5160 ctgagaaaca tcacccattc tctctccata ccacctcaca aaaattttcg ccgccccaac 5220 acttcaacac tgttttgttt tatttttctt attaatataa gaaggcagga atgtcaggcc 5280 tctgagccca agccaagcca tcgcatcccc tgtgacttgc acatatacgc ccagatggcc 5340 tgaagtaact gaagaatcac aaaagaagtg aaaatgccct gccccgcctt aactgatgac 5400 attccaccac aaaagaagtg aaaatggccg gttcttgcct taagtgatga cattaccttg 5460 tgaaagtcct tttcctggct caaaaagctc ccccactcag taccttgtga cccccacccc 5520 tgcctgccag agaacaacgc ccctttttcc tttacctacc caaatcctat aaaacggccc 5580 cacccttatc tcccttcact gaccctcttt tcggactcag cccacctgca tgcacccagg 5640 tgaaataaac agccttgttg ctcacacaaa gcctgtttgg tggtctcttc acatggacgc 5700 gcatgaaa 5708 <210> 74 <211> 972 <212> DNA <213> Homo sapiens <400> 74 gtggggaaaa gaaagagaga tcagattgtt actgtgtctg tgtaggaaga agtagacata 60 agagactcca ttttgttctg tactaagaaa aattgttttg ccttgagacg ctgttaatct 120 gtaaccctac ccccaaccct gtgctcccta agacatgggc tgtgtcaact cagggttaaa 180 tggattaagg gctgttcagg gtgtgctttg ttaaacaaat gcttgaaggc agcatgcttg 240 ttaagagtca tcaccactcc ctaatctcaa gtacccagag gcacactaca ctgcggaaga 300 ctgcagggtc ctctgcctag gaaagccagg tattgtccaa ggtttctccc catgtgatag 360 tctgaaatac agcctcgtgg gaagggaaag acctgactgt cccccagccc gacacccgta 420 aagggtctgt gctgaggagg attagtaaaa gaggaaggaa ggcctctttg cagttgagat 480 aagaggaagg catctgtctc cggctcgtcc ctgggcaatg gaatgtctcg gtgtaaagcc 540 cgattgtata ttccatctac tgagatagga gaaaaccgcc ttaggactgg aggtgggaca 600 tgctggcagc aatactgctc tttaaggcat tgagatgttt ctgtatatgc acatcaaaag 660 cacagcactt ttttctttac cttgtttatg atgcagagac atttgttcac gtgtttacct 720 gctgatcttc tctccactat tatcctattg tcctgccaca tccccctctc cggaaatgcc 780 cgataatgat caataaatac taagggaact cagaggccag tgccggcatg ggtcctccgt 840 atgctgaacg ccggtcccct gggcccattt ttcttcctct gtactttgtc tctgtgtctc 900 tttcttttcc aagtctctcc ttccacctaa tgagaaacgc ccacaggtgt ggaggggcaa 960 cccatccctt ca 972 <210> 75 <211> 2294 <212> DNA <213> Homo sapiens <400> 75 tgactccttt ttcagactca gcccacctgc accaggtgat taaaaagctt tattgctcac 60 acaaatcctg ttggtggact ctcttcacac ggatgcactt gacattttgt gctgaagacc 120 caggacagga ggactccttc gagagaccag tcccccatcc ttgccctcac tcggtgagga 180 gatctaccta tgacctcagg tcctcagacc aaccagccca aggaacatct caccaatttc 240 agatcgggta agcggtcgtt tcactccctt ctccaacctc tctcactatc cctccaccct 300 tcaatctctc ccttccttaa ttttggttcc ttttcccctt tctggtagag acagaggaga 360 tgcattttat ctgtgaactc aaaactccag cgctggtcac agactcggga agacagtctt 420 cccttggtgt ttaatcactg cggggacgcc tgcctgatta ttcacccaca tttcagaggt 480 gtctgatcac catggggatg cctgccttga tccttcacct tggtggcaag taccaccccc 540 cgccctctgt gtctctaccc tctcttttct ctaaacttac ccttttacta tgggcaacct 600 tctgccctcc attcctcctt cttctccctt ggcctttgtt ctaaaaaact taaaacctct 660 tcaactccca cctgatctaa aacctaagcg tcttattttc ttctgcaaca ctgcttggcc 720 ccaatacaaa cttggtaatg gctccacata gtcagaaaat ggcactttcg attttctcca 780 tcctacaaga tctagataat ttttttcaaa aaatgggcaa atggtctgag gtgcctgata 840 tccaggcatt cttttataca ttggtccctc cctagtctct gctcccaatg tgactgtccc 900 aaatctttct tgtttttctc ccgtctgttc cttcagtctc caccccaagc tctgagtcct 960 ttgaatcttc cttttctaca gacccaccta acctctcccc tccaccccag gctgctcctc 1020 gccaggccga gccaggtccc aattcttcct cagcctccac tcccccaccc tgtaatcctt 1080 ctatcacctc ccctcctcat acccagtctg gcttacaatt ttgttccaca acttgccctc 1140 ccccacctgc ccaacaattt cctcttagag aagtggctgg agctgaaggc atagtcaagg 1200 ttaatgctcc tttttcttta gccaacctct cccaaatcag ttagcgttta ggctcttttt 1260 catcaagtat aaaaacccag cccagttcat ggcccatttg gcaacaaccc ttagacgctt 1320 tactgcccta gacacagagg ggccagaagg ccgtcttatt ctcaatatgc attttattac 1380 ccaatccact cctgacatta gaaaaagctc caaaaattaa gattctggcc ctcaaacccc 1440 acaacaggac ttaattaacc tcgccttcaa ggtgtacaat aatagaggca gccaagtggc 1500 cacgtatttc tgagttgcaa ttccttgcct ccactgtaag acaaacccca gccacatttc 1560 cagcacacaa gaacttcaaa aacctaaacc atagcagcca ggcattcctc caggacctcc 1620 tcccccagga tcttgcttca agtgccagaa atctggccac tgggccaagg aatgcccgca 1680 gcccaggatt cctcctaaga tgtgtcccat ctgtgtggga ccccactgga aattggactg 1740 tccagctctc ccagcagcca ctcccacagc ccctggaact gtggcctaag gctctctgac 1800 tcctttccag atcttctcag cttagcggct gaagactgac gctgcccgat tgattgcctg 1860 ggaagcctcc tggaccatca cagacgcctt gggtaactct tacagtggag gacaggaatg 1920 tcaggccggc ctctgagccc aagcatgcat gtatacatcc agatggcctg aggcaactga 1980 agaaccacaa aagaagtgaa aatggctagt tcctgcctta actgatgaca ttaccttgtg 2040 acattccttc tccgggacag tgagtctccg gagctcccca ctgagcacct tgtgaccccc 2100 gcccctgccc gcaagagaac aacccccttt aactgtaatt ttccaccacc tacccaaatc 2160 ctaaaaaacg gccccactcc tatctccctt tgctgactcc tttttcggac tcagccaacc 2220 tgcacccagg tgattaaaaa gctttatttc tcacccaaag cctgttggtg gtctcttcac 2280 acggatgcgc atga 2294 <210> 76 <211> 5711 <212> DNA <213> Homo sapiens <400> 76 gtcaggcctc tgagcccaag ccaagccatc acatcccctg tgacttgcac ggatatgacc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aaggccctgc cccgccttaa 120 ctgatgacat tccaccattg tgatttgttc ctgccccacc ttaactgagt gattaaccct 180 gtgaatttcc ttctccaggc tcagaagctc ccccactgag caccttgtga cccccgcccc 240 tgcccaccag agaacaaccc cctttgactg taattttcca ttgccttccc aaatcctata 300 aaacggcccc atccctatct cccttcactg actctctttt cggactcagc ccgcctgcac 360 ccacgtgaaa taaacagcca tgttgctcac acaaagcctg tttggtggtc tcttcacacg 420 gacacgcatg aaatttggtg ctgtgactca gatcggggga cctcccttag gagatcaatc 480 ccctgtcctc ctgctttttg ctccataaga tccacctagg acctcaggtc ctcagatcga 540 ccagcccaag aaacatctca ccaatttcaa atccggtaag cggcctcttt ttactctctt 600 ctccaacctc cctcactatc cctcaacctc tttctccttt caatcttgga accacacttc 660 aatctctccc ttctcttaat ttcaattcct ttcattttct ggtagagaca aaggagacac 720 gttttatcca tggacccaaa actccagcgc tggtcacgga ctagggaagg cagcctttcc 780 ttggtgttta atcattgcag ggacgcctct ctgattattc acctatgttt caaaggtgtc 840 agaagacaca gggatgcctg ccttggtcct tcacccttag cggcaagtcc cgcttttctg 900 gggaaggggc aagtacccca accccttctc tccttgtctc tatctcttct ctgcttttct 960 gggggagggg caagtaccct tcaaccccat ctccttcact gttagtggca agtcccactt 1020 ttctagaggg gtaagtaccc cagcctcgta tctctgcgcc ccaatccctt atttccatgc 1080 cccgacccct tatttccgtg ccctgacccc ttatttccat gccctgaccc cttatttctg 1140 tgccccatcc cttatttcca tgccccgacc tcttatctct gagccccaac cacttttccc 1200 acttttctag aaggtaagaa cccccaaacc ccttccctcc atttctctac tctctctttc 1260 ctctaggctt gcttccttcg ctataggcaa ccttccaccc tccattcctc cttctactcc 1320 cttggcctgt gttctcaaaa acttaagacc tcttcaactc acacccgacc taaaacctaa 1380 atgtcttatt ttcttctgca atgccgcttg accccaatat aaacttgaca gtagttccaa 1440 atagccagaa aacggcactt tcaatttttc catcctacag gatctaaata attcttgttt 1500 taaaataggc aaatggtctg aggtgcctga catccaggca ttcttttaca catcagtccc 1560 ttcctagtct ctgtgcccag tgcaactcct cccaaatctt ccttctttcc ctcctgcctg 1620 tcccctcagt cccaacccca agcgtcactg agtctttcta atcttccttt tctacagacc 1680 catctgacct ctcccctcct cgccaggctg agctaggtcc caattcttcc accctataat 1740 ctctttatcg cctcccctcc tcacacctgg tccagcttac agtttctttc cgtgactagc 1800 cctcccccac ctgcccagca atttactctt aaaaaggtgg ctggagccaa aggcatagtc 1860 aaggttaatg ctcctttctc tttatcccaa atcagatagc gtttaggctc tttttcatca 1920 aatataaaaa tccagcccag ttcatgactc gtttggcagc aaccctgaga agctttacag 1980 ccctagaccc taaaaggtca aaaggccatc ttattctcaa tatacatttt attacccaat 2040 ctgctcccga cattaaataa aactccaaaa attagaatct ggccgtcaaa ccccacaaca 2100 ggacttgatt aacctcacct tcaaggtgta caataataga aaaaacttgc aattccttgc 2160 ctccactgtg agacaaaccc cagccacatc tccagcacac aagaacttcc aaatgcctga 2220 ctgaactgca gcagccaggc attcctccag aacctcctcc cccaggagct tgctacaagt 2280 gccagtaatc tgaccaccag gccaaggaat gcctgcagcc caggattcct cctaagctgt 2340 gtcccatctg tgcaggaccc cactggaaat cggactgttc aactcacctg gcagccactc 2400 ccagagcccc tggaactctg gcccaaggct ctctgactga ctccttcttg gcttaatggc 2460 taaagactga tgctgcccga tcgcctcgga agcccctaga ccatcacgga tgccgagctt 2520 caggtaactc tcacagtgga aggtaagccc gtccccttct taatcaatac ggaggctacc 2580 cactccacat taccttcttt tcaagggcct gtttcccttg cctccataac tgttgtaggt 2640 attgacagcc aggcttctaa acttcttaaa actccccaac tctggtgcca actgagacaa 2700 tactctttta tgcactcttt tttagttatc cccacctgcc cagttccctt attaggctga 2760 gatattttaa ccaaattatc tgcttccctg actattcctg gactatagcc gcatctcatt 2820 gctgcccttc ttcccaatcc aaagcctcct ttgcatcctc ctcttgtatt cccccacctt 2880 aacccacaag tataaaatac ctctactcct tccttcggga ctgatcatgc accccttacc 2940 atctcattaa aacctaatca cccttacccc gctcaacacc aatatcccat cccacagcat 3000 gctgtaaaag gattaaaacc tgttatcact cgcctgctac agcatgggct tctaaaacct 3060 ataaactctc cttaccattc ccccatttta cctgtcctaa aaccagacaa gccttacaag 3120 ttagttcaga atctgtgcct tatcaaccaa attgttttgc ctatccaccc catggtgcca 3180 aacccatata ctctcctatc ctcaatagct ccctctacta cccattattc tgttctggat 3240 ctcaaacatg ctttctttac tattcctttg cacccttcat cccagcctct ctttgtcttc 3300 acttagactg accctgacac ccattaggct cagcaaatta cctgggctgt actgccacaa 3360 ggcttcacag acagccccca ttacttcagt caagtccaaa ttttatcctc acctgttacc 3420 tatctcggca taattctcat aaaaacacac gtgctctccc tgctgatcat gtccaattaa 3480 tctcccaaac ctcaatccct tacaaaagaa caaccctttc cttcctaggc atggttagtg 3540 cggtcagaat tcttacacaa gagccaggac cacaccctgt agcctttctg tccaaataac 3600 ttgaccttac tgttttagcc tagccctcag gtctgcgtgc agaggctgcc actgctttaa 3660 tactgttaga ggccctaaaa atcacaaact atgctcaact cactctctac atttctcata 3720 acttccaaaa tctattttct tcctcataac tgacgcatat actttctgct ccccggctcc 3780 ttcagctgta ctcactcttt aagtcccaca attaccattg ttcctggccc agacttcaaa 3840 ctggcctccc acattattcc tgataccaca cctgaccccc atgactgtat ctctctgatc 3900 cacctgatat tcaccccatt tccccatatt tccttctttc ctgttcctca ccctgatcat 3960 gcttgattta ttgatggcag ttctaccagg ccttatcgcc acacaccagc aaaggcaggc 4020 tatgctatag tacaagccac tagcccgcct ctcagaacct ctcatttcct ttccatcgtg 4080 gaaatctatc ctcaaggaaa taacttctca gtgttccatc tgctattcta ctactcctca 4140 gggattattc aggccccctc ccttccctac acatcaagct cgaggatttg ctcccaccca 4200 ggactggcaa attagcttta ctcaacatgt ccggagtcag ataactaaaa tacctcttag 4260 tctaggtaga cactttcact ggacaggtag agtcctttcc tacagggtct gagaaggcca 4320 ccgcagtcat ttcttccgtt ctgtcagaca taattcctcc gtttagcctt cccacctcaa 4380 tacagtctga taacagacca gcctttatta gtcaaatcag ccaagcagtt tttcaggctc 4440 ttagtattca gtgaaaccat tatatccctt accgtcctcc gtctacaaga aaagtagaac 4500 ggactaaagg tcttttaaaa acgcacctca ccaagctcag ccaccaactt aaagaggact 4560 ggacaatact tttaccactt tcgcttctca gaattcaggc ctgtcctcag aatgctacaa 4620 ggtacagcca atttaagctc ctgtatagac gctccttttt attaggcccc agtctcattc 4680 gacaccagac caacttagac tgtgccccaa aaaaacttgt catccctact atcttctgtc 4740 tagtcatact cctattcacc attctcagct actcatacat gccctgctct tgttgacact 4800 gccggtttac actgtttctc caagccatca cagctgatat ctcctggtgc tatccccaaa 4860 ctgccactct aaactcttga agtaaataag taatctttgc tggcaggact atgctgaatc 4920 tccttaggca ctctctaatc agatgtccta ggtcctccca attcttagac cttttatacc 4980 tgtttttctc cttttgttat tccatttagt ttttcagttc atacaaaacc gtatccaggc 5040 catcaccaat aattctacac gacaaatgtg tttcttctag catccccaca atatcacccc 5100 ttaccacaaa tcttccttca gcttaatctc tcccactcta ggttcccacg ccgcccctaa 5160 tcccgcttga agcagccctg agaaacatcg tccactctct ctccatacca cccccaaaaa 5220 ttttcaccgc cccaacactt caacactatt ttatttttct tattaagaag gcaggaatgt 5280 caggcctctg agcccaagcc aagccatcac atcccctgtg acttgcacgg aaaggaccag 5340 aaggcctgaa gtaactgaag aatcacaaaa gaagtgaaaa ggccctgccc cgccttaact 5400 gatgacattc caccattgtg atttgttcct accccacctt aactgagtga ttaaccctgt 5460 gaatttcctt cttctggctc agaagctccc ccactgagca ccttgtgacc cccgcccctg 5520 cccaccagag aacaaccccc tttgactgta attttccatt accttcccaa atcctataaa 5580 acagccccac ccctatctcc cttcactgac tctcttttcg gactcagccc gcctgcaccc 5640 aggtgaaata aacagccatg ttgctcacac aaagcctgtt tggtggtctc ttcacatgga 5700 tgcgcatgaa a 5711 <210> 77 <211> 823 <212> DNA <213> Homo sapiens <400> 77 agtgaagaag tgaaatctgg gctgcactaa ccaatggaaa ttacttaaaa cccttcacca 60 aacctttcac ttaggcattg atagcaccca gacgcccaaa ttattattta ctggaccagg 120 ccttttcaaa actatcaagc agatagtcag ggcctgtgaa gtgtgccaaa gaaataatcc 180 cctgcactgc aggccataca tttcaatccc tgtatcttta acctccttgt taagtttgtc 240 tcttccagaa tcgaagctgt aaaactaaaa atgttcttca aatggagccc cagatgcagt 300 ccatgaataa gatctaccgt ggacccctgg accggcctgc tagcccatgc tccaatgtta 360 atgacattga aggcacccct cccgaggaaa tctcaactac acaaccccta ctacacctca 420 attcagcagg aagaagttag agcggtcgtt ggccaacctc gccaacagca cttaggtttt 480 cctgttgaga gggggtacta agagacagga ctagctggat ttcctagggt gactaagaat 540 ccctaagcct agctgggaag gtgaccacat ccacctttaa acatggggtt tgcaacttag 600 ctcacacccg accaatcagg tagtaaagag agctcactaa aatgctaatt aggcaaaaac 660 aggaggcaaa gaaatagcca atcatctatt gcctgagagc acagtgggaa ggataatgac 720 tgggatataa acccaggcat tcaagccagc aatggctacc ctctttgggt cccctccctt 780 tgtatgggag ctctgttttc actccattaa atcttgcaac tgc 823 <210> 78 <211> 765 <212> DNA <213> Homo sapiens <400> 78 gagagacagg actagctgga tttcctaggc cgactaagaa tccctaagcc tagctgggaa 60 ggtgaccact tccaccttta aacatggggc ttgcaactta gctcacacct gaccaatcag 120 atagtaaggg gagctcacta aaatgctaat taggcaaaaa caggaggtaa agaaatagcc 180 aatcatctgt tgcctgggag cacagcagga gggacaatga tcaggatata aacccaggta 240 ttcgagccag caatggcaac cccctttggg tcccctccct ttgtatggga gctctgtttt 300 cactctattt cactctatta aatcttgcaa ctgcactctt ctgtgtttgt tatggcttga 360 gctgagcttt cgctcacagt ccaccactgc tgtttgccac agtcacagac ccgctgctca 420 cttcaatccc tccagatccc gcagggtgtc cgctgtgctc ctgatccagc gaggcaccca 480 ttgccactcc cgatcgtgct aaaggcttgc catttttcct gcatggctaa gggcctgggt 540 tcatcctaat cgagctgaac actagtcact gggttctaca gttctcttcc atgacccaca 600 gcttccaata gagctataac actcaccgca tggcccaaga ttccattcct tggaatccgt 660 gaggccaaga cccccaggtc agagaacacg aggcttgcca ccatcttgga agcggctcac 720 caccatcttg ggagctctgt gagcaaggaa ccccagtaac aattt 765 <210> 79 <211> 5749 <212> DNA <213> Homo sapiens <400> 79 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac gtatacgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aagaccctgc cctgccttaa 120 ctgatgacat tccaccattg tgatttgttc ctgccccacc ttaactgagt gattaaccct 180 gtgaatttcc ttctcctggc tcagaagctc ccccactgag caccttgtga cccccgcccc 240 tgcccaccag agaacaaccc cctttgactg taattttcca ttaccttccc aaatcctata 300 aaatggcccc acccctatct ccctttgctg actctctttt cggactcatc cggcctgcac 360 ccaggtgaaa taaacagcca tgttgctcac acaaagcctg tttggtggtc tcttcacacg 420 gacgcgcatg aaatttggtg ccatgactca gatcagggga cctcccttgg gagatcaatc 480 ccctgtcctc ctgttctttg ctccgtgaga aagatgcacc tacgacctca ggtcctcaga 540 ccgaccagcc caaggaacat atcaccaatt ttaaatcagg taagcggtct cttcttactc 600 tcttctccaa cgtctctcac tgtccctcaa ccactttctc ctttccactc ttcaatctct 660 cccttctctt aatttcaatt cctttcattt tctgggagag acaaaggaga cacgttttat 720 ccgtggaccc aaaactccgg cggcggtcac ggactgggaa ggtagccttc ccttggtgtt 780 taatcattgc agggacgcct ctgattattc acccacgttt caaaggtgtc agaccacgca 840 cggacgcctg ccttggtcct tcacccttgg cggcaagtct cgcttttctg gggaaggggc 900 aagtacccca accccttctc tccttgtctc taccccttct ctgctttcct ggggcagggg 960 caagtacccc tcaacctctt cttcaccctt agctgctagt cccgctttcc tagggggcaa 1020 gaacccccca atcgcttatt tccacgcccc aacctcttat ctctgtgcca caatcgctta 1080 tttccgcgcc ccaacctctt atctctgcgc cccaattgct tatttccgcg ccccaacctc 1140 atctctgcgc cccaatccct tatttccgcg ccccaacctc ttatctctgt gccccaatcc 1200 cttatttccg tgccccaaca ctttctctgc ttttctggag ggcaagaaac ccccacccct 1260 tctgcgtgtc tctactcttt tctctgggct tgcctccttc gctatgggca agcttccacc 1320 ttccattcct ccttcttctc ccttagcctg tattcttaag aacttaaaac ctcttcaatt 1380 ctcacctgac ctaaaatcta agcgcctcat tttcttctgc aacaccgctt gaccccaata 1440 caaactcgac agtagttcca aatagccgga aaacagcact ttcaattttt ccatcctaca 1500 agatctaaat aattcttgtc gtaaaatggg caaatggtct gaggtgcctg acgtccaggc 1560 attcttttac acatcagtcc cttcctagtc tctgtgccca gtgcaactcg tcccaaatct 1620 cccgcctgtc ccctcagtcc caaccccaag cgtcgctgag tctttctaat cttccttttc 1680 tacagaccca tctgacctct cccttcctcc ccagcctgct ccttgccagg ccaagctagg 1740 tcccaattct tcctcagcct ctgctcctcc accctataat ctttttatcg cctcccctca 1800 cacctgatcc ggcttacagt ttcgttccgt gactagccct cccccacctg cccagcaatt 1860 tactcttaaa aaggtggctg gagagctaaa ggcatagtca aggttaatgc tcctttttct 1920 ttatcccaaa tcagatagcg tttaggctct ttttcatcaa atataaaaat ccagcccagt 1980 tcatgacttg tttggcagcg accctgagac gctttacagc cctagaccct aaaaggtcaa 2040 aaggccgtct tattctcaat atacatttta ttacccaatc tgctcccaac attaaataaa 2100 actccaaaaa ttggaatctg gccctcaaac cccacaacag gacttaatta acctcacctt 2160 caaggtgtgc aataacagaa aaaagttgca attccttgcc tccactgtga gacaatcccc 2220 agtcacatct ccagcacaca agaacttcca aacgcaacca ggcgttcctc cggaacctcc 2280 tcccccagga gcttgctaca cgcgccggaa atctggccac tgggccaagg aatgcccgca 2340 gcccgggatt cctcctaagc cgcgtcccat ctgtgcggga ccccactgaa aatcggactg 2400 ttcaactcac ctggcagcca ctcccagagc ccctggaact ctggctcaag gttctctgac 2460 tgactccttc ttgacttacc ggctgaagac tgatgctgcc tgatcgcctc agaagccccg 2520 tagaccatca cggatgccga gctttaggta actctcacgg tggagggtaa gtccgtcccc 2580 ttcttaatca atacggaggc tacccactcc acattacctt cttttcaagg gcctgtttcc 2640 cttgcctcca taactgttgt gggtattgac ggccaggctt ctaaacctct taaaactccc 2700 caactctggt gccaacttag acaatactct tttaagcact cctttttagt tatccccacc 2760 tgcccagttc ccttattagg ctgagacact ttaactaaat tatctgcttc cctgactatt 2820 cctggactac atctatatct cattgccgcc cttcttccca atccaaagcc tcctttgcgt 2880 cctcctcttg tatcccccca ccttagccca caagtataag atacctctac tccctccttg 2940 gcgaccgatc gtgcacccct taccatctca ttaaaaccta atcaccctta ccccactcaa 3000 cgccaatatc ccatcccgca gcacgcttta aaaggattaa agcctgttat cactcgcctg 3060 ctacagcatg gccttttaaa gcctataaac tctccttaca attcccctat tttacctgtc 3120 ctaaaaccag acaagcctta caagttagtt caggatctgc accgtatcaa ccaaattgtt 3180 ttgcctatcc cccctgtggg gcccaacccg tacactcttt tgtcctcaat acctccctcc 3240 acaactcact attccgtgct tgatcgtaaa gatgctttct tcactattcc cctgcacccc 3300 tcgtcccagc ctctctttgc tttcacttag actgaccctg acacccatta ggctcagcaa 3360 attacctagg ctgtactact gcaagacttc atagacagcc cccattactt cagtcaagcc 3420 caaatttcat cctcatctgt tacctatctc ggcataattc tcataaaaac acacgtgctt 3480 tccctgctga tcgtgtccga ttaatctccc aaacctcaat cccttacaaa ataacaactc 3540 ctttccttcc taggcatggt tagtgcggtc agaattctta cacaagagcc aggactgcgt 3600 cctgcagcct ttctgtccaa acaacttgac cttactgttt tagcctagcc ctcatgtctg 3660 cgtgcagcgg ctgccgctgc tttaatactt ttagaggccc taaaaatcac aaactatgct 3720 caactcactc tctacatttc tcataacttc caaaatctat tttcttcctc atacctgacg 3780 catatacttt ctgctccccg gctccttcag ctgtactcac tctttgttaa gtcccacaat 3840 taccattgtt cctggccggg acttcaatct ggcctcccac attattcctg ataccacacc 3900 tgacccccat gactgtatct ctctgatcca cctgatactc accccatttc cccatatttc 3960 cttctttcct gttcctcacc ctgatcacgc ttgatttttt gatggcagtt ccaccaggcc 4020 taatcgccac acaccagcaa agccaggcta tgctatagta caagccacta gcccacctct 4080 cagaacctct catttccttt ccatcgtgga aatctatcct caaggaaata acttctcagt 4140 gtttcatctg ctattctact actcctcagg gattattcag gccccctccc ttccctacac 4200 atcaagctcc aggatttgcc cccacccagg actggcaaat tagctttact caacatgccc 4260 gagtcaggaa actaaaatac ctcttagtct aaatagacac tttcactgaa taagtaaagg 4320 cgtttcctac agggtctgag aaggccacca cagtcatttc ttcccttctg tcagacataa 4380 ttcctcagtt tagccttccc acctctatac agtctgatag cagaccagcc tttattagtc 4440 aaatcagcca attagttttt caggctctta gtattcagtg aaacctttat atcccttacg 4500 gtcctctatc ttcaagaaaa gtagaacgga ctaaaggtct tttaaaaaca cacctcacca 4560 agctcagcca ccaacttaaa aaggactgga caatactttt accactttcg cttctcagaa 4620 ttcaggcctg tcctcagaat gctacaaggt acagcccatt taagctcctg tatagatgct 4680 cctttttatt aggccccagt ctcattccag acaccagacc aacttagact gtgcccccaa 4740 aaaaaacttg tcatccctac tatcttctgt ctagtcatac tcctattctc cgttctcaac 4800 tactcataca tgccctgctc ttgtttacac tgccagttta cactgtttct ccaagccatc 4860 acagctgata tctcctcgtg ctatccccaa actgccactt ttaactcttg aagtaaataa 4920 ataatctttg ctggcaggac tatgctgaat ctccttaggc actctctaat cagatgtcct 4980 aggtcctccc aattcttaga ccttttatac ctgtttttct ccttcttatt ccatttagtt 5040 tttcaattca tacaaaacca tatccaggcc gtcaccaatc attctacaca acaaatgttt 5100 cttctaacat ccccacaata tcacccctta ccacgagacc tcccttcagc ttaatctctc 5160 ccactctagg ttcccacgcc gcccctaatc ccactcgaag cagccctgag aaacatcgcc 5220 cattctctct ccataccacc ccccaaaaat tttcgtcgcc ccaacacttc aacactattt 5280 tgttttattt ttcttattaa tataagaagg caggaatgtc aggcctctga gcccaagcca 5340 agccatcgca tcccctgtga cttgcgcgta tacgcccaga tggcctgaag taactgaaga 5400 atcacaaaag aagtgaaaag gccctgcccc gccttaactg atgacattcc accattgtga 5460 tttgttcctg ccccacctta actgagtgat taaccctgta aatttccttc ttctggctca 5520 gaagctcccg cactgagcac cttgtgaccc ccgcccctgc ccaccagaga acaaccccct 5580 ttgcatgtaa ttttccatta ccttcccaaa tcctataaaa cggccccatc cctactccct 5640 ttgctgactc tcttttcgga ctcatccggc ctgcacccag gtgaaataaa cagccatgtt 5700 gctcacacaa agcctgttta gtggtctctt cacacagacg cgcatgaaa 5749 <210> 80 <211> 83 <212> DNA <213> Homo sapiens <400> 80 gtgaggcctc tgagcccaag ctaagcctgt gacctgcaca tatacaccca gatggcctgg 60 agcaactgaa gaaccacaaa aga 83 <210> 81 <211> 972 <212> DNA <213> Homo sapiens <400> 81 gtggggaaaa gaaagagata tcagattgtt actgtgtctg tgtaggaaga agtagacata 60 agagactcca ttttgttctg tactaagaaa aattcttttg ccttgagacg ctgttaatct 120 gtaaccctac ccccaaccct gtgctcccta agacatgggc tgtgtcaact cagggttaaa 180 tggattaagg gctgttcagg gtgtgctttg ttaaacaaat gcttgaaggc agcatgcttg 240 ttaagagtca tcaccactcc ctaatctcaa gtgcccagag acacactaca ctgcggaaga 300 ctgcagggac ctctgcctag gaaagccagg tattgtccaa ggtttctccc catgtgatag 360 tctgaaatac agcctcgtgg gaagggaaag acctgactgt cccccagccc gacacccgta 420 aagggtctgt gctgaggagg attagtaaaa gaggaaggaa ggcctctttg cagttgagat 480 aagaggaagg catctgtctc ctgctcatcc ctgggcaatg gaatgtctcg gtgtaaagcc 540 cgattgtata tcccatctac tgagatagga gaaaactgcc ttaggactgg aggtgggaca 600 tgctggcagc aatactgctc tttaaggcat tgagatgttt ctgtatatgc acatcaaaag 660 cacagcactt ttttctttac cttgtttatg atgcagagac atttgttcac gtgtttacct 720 gctgatcttc tctccactat tatcctattg tcctgccaca tccccctctc cggaaatgcc 780 cgataatgat caataaatac taagggaact cagaggccag tgctggcatg ggtcctccat 840 atgctgaacg ccggtcccct gggcccattt ttctttctct gtactttgtc tctgtgtctc 900 tttcttttcc aagtctctcc ttccacctaa cgagaaacgc ccacaggtgt ggaggggcaa 960 cccatccctt ca 972 <210> 82 <211> 4076 <212> DNA <213> Homo sapiens <400> 82 gtcaggcctc tgagcccaag ctgagccatg atattccctg tgacctgcac gtacacatcc 60 agatggccag ttcctgcctt aactgatgac attccaccac aaaagaagtg aaaatggcct 120 gttcctgcct taactgatga caatgtcttg tgaaattcct tctcctggct catcctggct 180 caaaagctcc cccactgagt accttgtgac ccccactcct gcccgccaga gaacaacccc 240 ctttttcctt cacctatcca aatcctataa aacggcccca cccccatctc ccttcgctga 300 ctctcttttc ggactcagcc cgcctgcacc caggtgaaat aaacagccat gttgctcaca 360 caaagcctgt ttggtggtct cttcactcag acacgcagga aatttggtgc cgtgacttgg 420 attgggggac ctcccttgag agatcaaccc ctgtcctcct gtcctttgct ccgtgagaaa 480 gatccaccta cgacctcagg tcctcagacc taccagccca aggaacatct caccaatttt 540 aaatcgggtg agcggcctct tcttactctc ttctccaacc tctctcactg tccctcaacc 600 actttctcct ttccactctt caatctctcc cttctcttaa tttcaattcc tttcattttc 660 tggtagagac aaaggagaca cgttttatcc gtggacccag aactctggca ccggtcaagg 720 actagggaag gcagccttcc cctggtgttg aatcattgca gggatgcctc tctgattatt 780 tacccatgtt tcagaggtgt cagaccatgc agggacacct gcctttgtcc ttcatcctta 840 gcggcaagtt ccgcttttct gtgggagggg caagtacccc aaccccttct ctccgtgtct 900 ctacaccttc tctgcctttc tggggggcaa gaaaccccca accccttctt cttcaccctt 960 agcagcaagt cccgcttttc taggggaggg ataattaccc caacccctta tatctctgtg 1020 ccctgatccc ttatttccgt gccccaagct cttatatctc tgcaccccaa tcccttattt 1080 ccatgcccca acctcttata tctctgcacc ctgatccctt atttcctcgc ccaacctctt 1140 atatctctgt gccccaatcc cttatttccg tgccctgacc tcgtatctct gtgccccatc 1200 ccctttccca cttttctgga gggtaagaac ccccgaaccc cttccctccg tgtctctact 1260 ctctcttttc tctgggcttg cctccttcac tatgggcaac cttccaccct ccattcctcc 1320 ttcttctccc ttagcctgtg ttcttaagaa cttaaaacct cttcaactct cacctgacct 1380 aaaatctaag catcttattt tcttctgcaa tgccacttga ccccaataca aactcgacag 1440 tagttccaaa tagccagaaa acggcacttt cgatttttcc atcttacaag atctaaataa 1500 ttcttgttgt aaaatgggca aatgatctga gatgcctgac gtccaggcat tcttttacac 1560 atcggtccct ctctagtctc tgttcccaat gcaactcatc ccaaatcttc cttctttccc 1620 tcctgtctgt cccctcagtc ccaaccccaa gcgtctctga gtctttctaa tgttcctttt 1680 ctacagaccc atctgacctc tcccctcctc cccaggctgc tcctcgccag gccgagctag 1740 gtcccaattc ttcctcagcc tccactcctc caccctataa tccttttatc acacctcccc 1800 tcctcacacc tggtccggct tacagttttg ttccatgact agccctcccc cacctgccca 1860 gcaatttact cttaaaaagg tggctggagc taaaggcata gtcaaggtta atgctccttt 1920 ttctttatcc caaatcagac agcatttagg ctctttttca tcaaatataa aaatccagcc 1980 cagctcatga ctcgtttggc agcaaccctg agatgcttta cagccctaga ccctaaaagg 2040 tcaaaaggcc gtcttattct caaaatgcat tttattaccc aatctgctcc cgacactaaa 2100 taaaactcca aaaattaaat tccggccctc aaaccccaca acaggattta attaacctcg 2160 ccttcaaggt gtacaatagt agaaaaaagt tgcaattcct tgcctccact gtgagacaaa 2220 ccccagccac atctccagca cacaagaact tccaaatgcc tgaaccgcag cggccagaca 2280 tttctccaga acctccttcc ccaggagctt gctacaagtg ccagaaatct ggccacaagg 2340 ccaaggaatg cctgcagccc aggattcctc ctaagccgcg tcccatctgt gcgggactcc 2400 actggaaatc ggactgtcca actcacctgg cagccactcc cagagcccct ggaactctgg 2460 ccgaaggctc tctgactcct tcccagatct tcttggctta gtggctgaag actgatgctg 2520 cccaatcgcc tcgaaagccc cctagaccat cacggacgct gagcttcagg taactcacac 2580 agtggagggt aagtccgtcc ccttcttaat caatacggag gctactcact ccgcattacc 2640 ttattttcaa gggcctgttt cccttgcttc cataactgtg gtgcgtattg acagccaggc 2700 ttctaaacct cttaaaactc cccaaatctg gtgccaatta gacaatactc ttttaagcat 2760 tccttttagt tatccccacc tgcccagttc ccttattagg ctgagacact ttaactacat 2820 tatctgcttc cctgactatt cctggattac agttacatct catggctgcc cttcttccca 2880 atccaaagcc tcctttgcgt cctcctcttg tattccccca ccttaaccca caagtataag 2940 atacctctac tccctccttg gcaaccgatc atgcacccct taccatctca ttaaaaccta 3000 atcaccctta ccccgattga tgccaatatc ccatcccaca gcatgctttg aaaggattaa 3060 agcctgttat cactcgcctg ctacagcatg gccttttaaa gcctataaac tctccttaca 3120 attcccccat tttacctgtc ctaaaaccag acaagccttt caagttagtt caggatctat 3180 gccttatcaa ccaaattgtt ttgcctatct accccatggt gccaaaccca tacactctcc 3240 tatcctcaat acctccctcc acaatccatt attctgttct ggatctcaaa catgctttct 3300 tcactactcc tttgcacctg tcatcccagc ctctcttcgc tttcacttag actgaccctg 3360 acacccatca ggctcagcaa attacctggg ctgtactgcc gcaaggcttc acagacagcc 3420 cccattactt cagtcaagcc caaatttcat cctcatctgt tacctatctc ggcataattc 3480 tcataaaaac acatgtgctt tccctgctga ttgtgtccga ttaatctccc aaacctcaat 3540 cccttacaaa acaacaactc ctttccttcc taggcatggt tagtgcggtc agaattctta 3600 tacaagagcc aggaccacac cctgtagcct ttctgtgcaa acaacttgac ctgttttagc 3660 ctagccatca tgtctccgtg cagtggctgc tgccgcccta atacttttag aggccctcaa 3720 agtcacaaac tatgctcaac ttactctcta catgtctcat aacttccaaa atctattttc 3780 ttcctcatac ctgacacata tactttctgc tccccagctc cttcagctgt actcactctt 3840 tgttaagttc cacaattacc attgttcctg gcccggactt caatccggcc tcccacatta 3900 ttcctgatac cacaactgac acccatgact gtatctctct gatccacctg acattcaccc 3960 catttccccg tatttccttc tttcctgttc ctcatcctga tcatgcttga tttattgatg 4020 gcggttccat caggcctaat tgccacacac cagcaaaggc aggctatgct atagca 4076 <210> 83 <211> 10042 <212> DNA <213> Homo sapiens <400> 83 ttggagtagg tagttaggca gacatgaaca tcagaagaaa agcccatccc ccaccagtaa 60 tgtcaggcaa ccattaggtg atggtcaggt agttgttaag cagtcttttt aaaataataa 120 ttggttgcag tcagtgccag agaaaggcag tctcccaata tatggaaaac acttgaagcc 180 ggtggccaac agcttcccaa taaggagctg agcaagcagt ctcaagcatg cactaagagg 240 caaaatggca gagtttaact ggtgtatgac cagttcctct aggaacactt gactggcaag 300 ggaaaaacgc ctcaagtgag catgcacaca acttcagtaa atacactgtg catgtggccg 360 ctcacaagtg ctggcaggcc actgtgcatg tggatggccc accccaagga aaaatcaaga 420 gtggagagac acaaaactcc agaagcatgc caacatataa aaccccaagt caaaggtcaa 480 acagggcact tggatttctc aggttgccaa cttggccctc ttccaagtta ctttactttc 540 tttcattcct gctctaagag tttttaataa actcttactt ctgctcaaaa acttgccttg 600 gtctctcact ctcgcttatg cccctcagac aaattctttc ctttgaagag gcaagaaaca 660 agttcttgca gacccataca gattcactgc tgctaacata ctttgatgcc acatggcttg 720 gatacgttcc ccagtggtaa gaaatctcta tgcctctcct tctttggctg gagaagaagg 780 agatctgtac acagttttct tctccccttt cactctcctg ccttccaacc aattcccaga 840 actattactc tcagccacag tggctctgca cccgctggct gatctctcag cttaccctga 900 ccggtggctt acaggggtag gaaggacctt ggagtccaca ccatgtagac ctgaaatact 960 aatggccctc ctagacagga ggctcatgag agtggtaggg ctaaagccta acactgtgca 1020 atgtctgcaa tttcctctgc tttttcaaat acaattgtct ttttccccaa aacccacacc 1080 acctattctc ctgttttctc tgtgtgtgtt ctgaaacggc cttgtgtgcc caccacactg 1140 tctacctcag gggcaagtct gtctctcttc tttcactttg tatgccacgc aacttccttc 1200 tctacgttaa acacacactc cctgttattc gttcacccat ggctcttgtt gcatttgtac 1260 agcagcagag aaacaggctc ccttgcagat gtccattggc tcattgccag gatagacact 1320 aattagaacc ccagttcttc cagctcctta tgacttacca tacacttttc atccctgtta 1380 tgctccaggg tcaagttttt ggtggctttt gaagcagttt ttatggctgc ataggacatc 1440 actctgtggt tctttaagga tctcacctac ttgctttttt tgagttagca ccccctttgg 1500 gaggagagaa aattcttcct ttgccatttg tgggctctta tcccaagctc cgagttctcc 1560 aaagattcct ctttatgtca agagggcaaa taaacattgc tgttttgaat cccagggctg 1620 ctgtttatgt gagcatatga aggttttccg tcagtattcc tcatgcttcc tcccactttc 1680 tcctatagca gaggggttgt cctgtctact caagcatttc ttctggatat taccccagga 1740 ggacagggaa cctctaatac aaaattttct ccattcctct aatcacttcc ataccctcct 1800 caatgtgctt aaggactctc aaggtcatat ttaaagggag ggaagtgcag cctcttgcag 1860 cagttggctg aaaaacaagc ttctcatcta cttaaagaac atgggaaatg gattataaaa 1920 aaaaaagagg taatcatttt gttgccagaa tgctgtgagt aagagtcact ataagatcat 1980 ggagataagg atataggcca gcccaaggct gcaggtgcaa gagacaaagt acccatagga 2040 cagagagaga taaaggctgg tcacaggcca caggcacaga acagattacc attagaacag 2100 agatgaaggc aagcttaggg gtacctggta agaccggttt attctgaaac tccaaggata 2160 aataggggac ccctgttcac ttgggtattt cctctgttct caagtgggta attgtgatga 2220 gatgggacac aggtttgggt acccagtaag acaggttcat tctggaaccc taaggatgaa 2280 tgggggatgc cctgttcagg aaaggataat agggaaataa aaggagatac cttctttttc 2340 ctttttttct cctttgttgt atcttcacag atgggtaatc acatctccct actacagtac 2400 aaaccctttg gatgcatcct caagaactga aagtttgacc ccaaaaccct gaaaaggaaa 2460 aggctaatat ttttctgtat cacagcctgg ttttaataca agctccagga gcaggaatct 2520 tgaccagaaa gtggaagcat aaattttaaa tttttaatat gctctatcag ctagatctgt 2580 tttgccacta gcagggaaaa tagacagaaa tcccctatgt acaggcccta agaaacaacc 2640 cagacctttg ttgggcttgt aaaattgatc cagtgatgat agcagccata atcatgctgc 2700 cccatctggt tggttcggga gacccctcat tgggtttacc cagggctcaa gccctggagg 2760 aaccaagagt ggagcttagc tcaaacccta ccctttggcc ccattatatc caagtctcct 2820 ggccctggag ccttcccttc cctacccagg gccatcctct ggacaccacc ccctcaagtt 2880 atgctccctt caagaagtta gttgacctac tagagttcag actccattta atatgcaaga 2940 cctgagtcaa attaaaacag aactagggaa gtttatggag gatcctgaca aatgcatcaa 3000 agggttccat aaactgggct taacatttga actcacttgg agggatctct cagtcatact 3060 gggacaaacc ctgtctaagg gagaacatga ctccattatg gaggcacccc aaaaatttgc 3120 aaatgcaata cacatgactg accttggtgg ctaccctgta tgggccacca cagttcactg 3180 ggtcagcccc aattgggatt acaataccca tgggggcata tgggcaaaga attgcatgtt 3240 cttatgtctc gtagaaggaa tgaaagctag aagagccaag cctgtaaact ataataaaat 3300 tggtcttaat agatcaagga cctcttggaa accccaccac tttcctagag aggctacaag 3360 aggccctggt gaaacacact aacctagacc cagagacatc acaagggcaa ctggtcctga 3420 aggaccattt tttaactcag gcagccccac atatttggag gaaactctaa aaactagcac 3480 tggaccccaa aacccttatg cctgacatct tcaacatagc ttcctctgtc ttttacaacc 3540 aggactagga gaaagaggaa agggctcagg gaaagaagag gtaaaaggaa aagcagcagc 3600 tccaactatt ggctgcccta aaaatccacc agccctctcc aagttgccct cagaatactc 3660 tcccagttaa ctgccatcag tgtgggaagc caagacactg gaagacaaac tgccgcagtg 3720 ggacagatgg gaaaaatccc tacatggctt gccctttctg tcacaaactc aaccactgga 3780 aatggaactg ccctgagggc tgaagggccc ctagaacaga atcccaattc ctgatggcct 3840 taagctgaaa aggcccgcca ctccagcagc tcctggactg aacattacta ttgaagggac 3900 agagctaagg gctgctttgg atgtggcagg taggactata agttttcttt gggaaatggc 3960 cttcttggtg cttatgtctt catgggcaat tatcctccaa ggtgatgggg ttaaattggg 4020 tgcccataac ccaaaggttc actcctcatc tttgctgcct gtgaggggag actgtctttt 4080 ctcattcatt tttaatgata gcagaatgtc ctacactgct tttgggtaga gatattttat 4140 ttagactagg ggcttagtta accttttcca aatgcaatct tatgcctcaa ggaagtcaca 4200 cacaaggatg aacttcccag acttttccat taatccagaa gtctggggct caagaatatc 4260 aggaaaggtc ataatgataa tgcctatagt aactcagctc atggatcctt ctagctaacc 4320 ttgtagaagg cagcttcctc tttgacctct ggccaaaagg gacttcatcc cctaattgaa 4380 aaatgtctaa aacatggatt attaatatac tataactcgc tatgtaacac ccctgtctta 4440 cctgttaaaa agagcaatgg agcaatggac aatataggct agtccaggac ctgcaaatca 4500 taaatgaggc agtagtccca atacacccaa tggtccccaa cccatatatt attctaggag 4560 aagtaccccc agatgctcat ttgttctcag tcttagagct caaagatgct ttcttttgtg 4620 tctccctaga ctcatcctcc caatttgtat ttgcacttga attggggaat gaaaaaggaa 4680 ggagtctaca gctaatctgg atagtacttc cgcaaggttc cagagatggt tccaatttgt 4740 ttgggcaagt cttggctaga gatttgcagg acctaactct tgagggttga gggtgtctcc 4800 tacagtacat agatgacaga tgacctgtta atctgctccc ctacaagaga gttatgaatc 4860 ctgcatctag tccagacact agattttctc acagagggta caagatgtct aaggccaagg 4920 cacatcgatt aagaaaagag gtttaatacc tggggataat cctgatccca cagagaacat 4980 aagctttctc cagaatggat acaggccatc cttagaatac ctaccccaac cacctaaaag 5040 caactttggg cttttctggg gatcacaaga tattccagac tttcaatact ggcatatggt 5100 ggaattatta agtccttata tcaggttcta aaagaaggga ctcatcagga cccacttctc 5160 tgggaaaaag atcagaagca agcctttaga gaactaaaaa ctgccttctc acaagcccta 5220 gcccttgggc tacccatact aaccaaaccg tttcagcttt tcatcactga aagtaagctg 5280 tagccctgga agttctaact caaaccatca ggccatcaaa tgtcctatag gttacttttt 5340 aaagaaccta gacccagtag tgcaagggtg gccacactgc ctaaaggtag tggctgcagc 5400 agccctttta cccaaggagg ccctcaaaat cacaatggga cagtcggtca ggctcctgac 5460 attccaacta ataggcccct tattggatat aaaaagaccg caatggatca ctgacaacag 5520 actgctaaac taccaagtct tgttgtcaga aaacccacag gtaacagttg agtggtgttc 5580 cactcttaac ccagcctcct tactgccact actagaagag gataactgaa cacattcatg 5640 ttgtgagata cttaaccaaa tttatgccag ccaggaagac ttacaatatc agcccctagg 5700 ttatctagat gaaatatggt tttcagatag gattggcttt gtcaagaatg gagatagata 5760 tgcagggtat gctatatgtc ccttcaccca gttacagagg tggtagctct gtccctgggg 5820 acctcagtgc aactagctga cccatcacat tgaccagggc cctaaaactt ggggaaagaa 5880 aaagaataac cacatataca gattccaaat atgccttcct ggtgcttcac acccacatgg 5940 ctaaccagaa ggaaggggga tacctaacag cttggaatac tcctattaca tagagacctc 6000 caatcttaga gctactagag gctgttcatt tgcctcagga agtggcagca gtgcactgta 6060 aagaatacca caggggttct gatgaaactg catggggaaa tatgttatct gaccaaaaag 6120 ctaaagaggc agccatctca aaagacacct ctgtggggac tttactcccc tctctcccca 6180 gtgaactgcc cttctccaat acactaagga agaaatagat tgggccatcc agcatgggta 6240 taaagaagaa accaatggat ggtacatgtt gggagaactt ctccatctac ctaatgcttc 6300 ccagtggaaa gtcatcaagt gtttacttga ctcatgccac cttgaaaagg acagtctagg 6360 gtaaatttgt aaatgggtgt tcagtgggaa gggactaacc aaaattattc aataggtttg 6420 tcaagcctgc accttgtgaa ccacaaataa tccctagatg gggaagcccc ctccataata 6480 agtcaaatcc aaaggagagg tacatactct ggggaggact ggtagatgga cttcactcag 6540 ctacccacat gccacaggtg taagtacctc ttggtctgtg taggtacctt cacagaacgg 6600 gaagactcct gccccacaag gactgaaaag gcacaggaga tagctgactt gctcctaaag 6660 gaactcattc cctgctttga actccccagg tcattgcaga gtgacagtga ttcatctttt 6720 tttccccaag taacttaaca ggttagtaat gccctaggca tgaagtggta ccctcacttt 6780 gcctgagaac tgcaatcttc aggaaaagtg gaaagaattt accaaaccct gaaatgcatc 6840 ctcaataatc tctgtcagga aatagcagtc atgggtggac ctcttacctt taaccctcct 6900 tcaaatctgt attgccccta aggctcccta gcaattaagc ccctttgaga tcttatattg 6960 taggccattt ctatattcag acttatctga tactagatga agaaactgcc aaaatcaccc 7020 agtatgtttc ttctttagca ggcttccaac agactctctg ggaatatggg ttaaaaacaa 7080 acccaacgtc ggaaggggaa acaatcccag cctctgtatc ttccaggctc tagttctcat 7140 taaagcttgg aaggttgaaa ccccaaattc ctaactaact gtattctggg ggggccactt 7200 cactgctcca gtatctattc ccacagccat taaagtacca gagatagcca gctggataca 7260 tcatgcctgg gtgaagtcat ggaaaggcca tgcaacacca gagccagaac caacaccctc 7320 agctccagaa tacacttgtg aggcactgga agacctgaaa ttcctctttt agtgaaaaca 7380 taagtaatgc cccctcaaca tcctttcacc tcaaagtaag gtgatcctag tattaggaat 7440 tttactaaca attgttatga ttattatcac tattttaatc ccaacttgta caccaccagg 7500 agttccagtg gcagcttgct ttgtgatcaa tttctctctc tcacaatcac cttaggtcac 7560 catggctctg ctcctgttgg ttctcatact caacgcttta ctggcagcac actgccatcc 7620 tgatttcctg ttatgagaaa aagctcagca attgctccaa aacacaggat ccccttactc 7680 caccaaatgc tggttatgta ctagctcttc ctctaaaaca ccagggagag cttatccagc 7740 ctgtaccaga gattggacaa gcatagacat agagttacgt atttcctctc aacaggaccc 7800 taatctgaaa gagctatttg ggtctgcaaa taacattttt tgcaaaagca aagcagtatt 7860 tacttgacat ccacaaggca cctctcattt ttggatcaat cttttctaat atcactttaa 7920 tgggaataac ctctatttgt cttatggcca aaagaaaaag atggattgga tgtaggctct 7980 ttcccagtat agcttgtaat gttactctct ctgtagattc taaccaacag actgatggaa 8040 catacaccga aaaccaattc caccatcaac caagattccc caaaccttca aatattatct 8100 ttcttcaggc aactttgcta attaagtcca ttcagttttg ccagcaatgc ccaagctcat 8160 gcagtacttg aaatttctag ttccagcctg atgattataa ccaatgtctg caaattgcca 8220 acctcagctc cacagcagaa tgggttctaa tggagtaaac tcaaaattct ctttttttgg 8280 gaaaatgaaa ccaagggagc taatcagagc caaaccccat gtacccaagt gttagcaggc 8340 atgaatgtag ctaccagcta cctgggtgtg ttgtcatcct tggtattttt gggggctgtc 8400 ctcatctctt cttttgtttt gacatctcta cttgtcttaa aacccaagga gccttctgtg 8460 tttgtggcca atcagtttac caatgcctcc tcattaaatg gactggaact tgtaccatag 8520 attatgtacc cctggacatc tttatactcc ctggcaatct ctctcttcca gcaccaatcc 8580 atgggaattc tatcttgccc agggtgaaaa gggctatcca attaattccc cttcttatgg 8640 gcctcagcat tatagctggt atgggaacct aaactgccgg aatctcaaaa gcctccttga 8700 cctatagcca actctgaaag gaaatagcca gcaagtttaa tatcatggct aaaacctcaa 8760 ccatggccag agcaaattaa cactttagca gttgtagtcc tccaaaactg tcaaggacta 8820 gatatgttaa tggcagcaca gggaggaatt tgtttagctt tagatgaaaa atgttgcttt 8880 tgggtaaatc aatcagtaaa agtacaaaac aacatcagac aactcctaaa tcgagcctcc 8940 agcttacaag aacaagcctc tcgtggttag ttagattggt aaggaacctg gaaatgggat 9000 cttccctggg ttcttccctt tttaggccca catgttagcc tctacttttg ctcctttcag 9060 tccatgtctt caaaaatcta ataacccaat ttgtctcctt tctctcacct ttagatgatc 9120 aagttccaga tgatcctcag tgagggatac catcctttca atattcaaga gtcacccttc 9180 tacagaggac tcctagactt cccatcagtg ggacatggca gaggtgaaat cctgcccctg 9240 tctcccttag acctggctgg atactgcttc caacaaccca tgcagccacc ctgccctgac 9300 agctagcaag aggccaagac ccacagaaca atcaccatca cacctctgtc agcaggaagc 9360 agttacagaa gactgacctt catccagttt cccaaagaat tgggtcatgg atttttgcgg 9420 gggaaaatgt tagagtaggt aattaggcag acatgagtaa gggaggagag accccctcca 9480 actaggaatg tcaggtgagc atcagatgat catcaggtgg ttgttaaact ctctctctaa 9540 aataataata ggttgcaact ggcagcaggg aaagacaatc tcccaataga tagaaaagtc 9600 ctgaagctgg tgatcagcag cttcctagta agatctcagg atttgggcaa gcaggctcaa 9660 acatgggcac taagaggcaa aatcgtggag tttaactggt atacagactt cctctaaaaa 9720 cacatgactc atgcacatgt ggacagcctg ccccaaggaa aaatcaaaag aggagagatg 9780 caaaacccca gaagcatgcc aatatataaa accccaagtc taaggtcaaa cagggcactt 9840 ggatttctca agttgcccac ttggccctct tctaagtgta ctttatttcc tttcattcct 9900 gctctaaaac tttttaaatt tcactcctgc tcaaaaactt gcctcagtct ttcactctgc 9960 cttatgcccc ttggaagaat tatttccttc aagatggcaa aaagcaagct gctgcagacc 10020 catacagatt tgctgctgct aa 10042 <210> 84 <211> 5599 <212> DNA <213> Homo sapiens <400> 84 tgactccttt ttcagactca gcccgcctgc accaggtgaa ataaacagcc ttgtggctca 60 cacaaagcct gtttagtggt ctcttcacac agacacgtga gacacttggt gccaaagacc 120 cgggtcagtg ggactccttc gggagaccag tcccctgtcc tcaccctcac tccatgaaga 180 gatccaccta caacctcggg tcctcagacc aaccagccca aggaacatct cactgatttt 240 aaattgggta agtggcctct ttttactctc ttctccaacc tctctcacta tccctcaacc 300 tctttctcct ttcaatcttg gagccatcct tcaatctctc ccttctctta atttcaattc 360 ctttcatttt ctggtagaga caaaggagac accttttatc cgtggaccca aaactccggc 420 gtctgtcacg gactcgggaa gacagccttt ccttggtgtt taatcactgc ggggatgcct 480 ctctgattat tcgcccacgt tccattggtg tctgatctcc gcagggacgc ctgccttggt 540 cattcaccca cattcccttg gtggcaagtc aattgcaggg acacctgctt tggctgctca 600 cccacgctgc agcctggggc tgctgcccgc cccctttctc cgtgtctcta cccttctctt 660 taaacttgcc tccttcacca tgggcaacct tccacccttc attcctcctt ttcccttagc 720 ctatgttctc aagaacttaa aacctcttca actcttgcct gacctaaaat ctaagcgtct 780 tattttcttc tgcaacactg cttggcccca atacaaacac gacaatggtt ctaaatggcc 840 agaaaatggc acttttgatt tctccatcct acaagaccta gataattttt gtcaaaaaat 900 gggcaaatgg tctgaggtgc ctgacatcca ggcattcttt tacacgtcgg tccctcccta 960 gtctctgctc ccaatgcgac tcatcccaaa tctttcttct ttctctcctg tctgttcctt 1020 cagtctccac cccaagctct gagtcctttg aatccttctt ttctatggac tcatgtgacc 1080 tctccccttc tccccaggct gctcctcgcc aggccaagcc aggtcccaat tcttcctcag 1140 cctctgctcc ccgaccctat aatccttcta tcacctcccc tcctcacacc ggtctggctt 1200 acagtttcat tccgtgacta gccctcccca acctgcccag caatttcctc tttaaagggt 1260 ggctggagct aaaggcatag tcaaggttag tgctcttttt tctttatccc aaatcagata 1320 gcgtttaggc tctttttcat caaatataaa aacccagccc agttcatggc ccgtttggca 1380 gcaaccctga gatgctttat agccctagac cctgtaaggt cagaaggccg tcttattctc 1440 aatatgcatt ttattttatt acccaatctg ctcccgatat taaataaagc tccaaaaatt 1500 atgaaacccc acaacaggac ttaattaacc tcgccttcaa ggtgtacaat aatagagtag 1560 aggcagccaa gtagcaatgt atttctaagt tgtaattcct tgcctccact gtgagacaaa 1620 ccccagccac atctccagca cacaagaact ccaaacacct gaaccgcagc tgccaggggt 1680 tcctccagaa cctcccccca ccccaggagc ttgctacaag tgccggaaat ctggccactg 1740 ggccaaggaa tgcccgcagc ccgggattcc tcccaagcca tgtcccatct gtgcgggacc 1800 ccactggaaa tcggactgtc caactcgccc ggcagccact cccagagccc ctggaactct 1860 ggcccaaggc cccttcccag atcttctcgg cttagcggct gaagactgac actgcccgat 1920 cgcctcggaa gcctcctgga ccatcacaga tgctttaggt aattcttaca gtggagggta 1980 agtccatccc cttcttaatc aatacggagg ctacctactc cacattacct tcttttgaag 2040 ggcctgtttc ccttgcctcc ataactgttg tgggtattga cggccaggct tctaaatctc 2100 ttaaaactcc ccaactctgg tgccaacttg gacaacattc ttttatgcac tcctttttag 2160 ttatccccac ctgcccagct cccttattag gtcaagacat tttaactaaa ttatctgctt 2220 ccctgactat tcctgggcta cagccacacc tcattgccgc ccttttctcc agttcaaagc 2280 ctccttcaca tcctctcctt gtatctcccc accttaaacc acaagtatag gacacctcta 2340 ctccctcctt ggtgaccgat catgcacccc ttaccatccc attaaaacct aatcaccctt 2400 accctgctca atgccaatat cccatcccac agcatgcttt aaaaggatta aagcctgtta 2460 tcactcgcct gttacagcat ggccttttaa agcctataaa ctcttcttac agttccccca 2520 ttttacctgt ccaaaaaccg gacacgactt gcaggttagt tcaggatctg tgccttatca 2580 accaaattgt cttgcctatg caccccatga tgccaaagcc atatactctc ctatcctcaa 2640 tacctccctc cacaacctct ccacaaccca gtattctatt ctggatttca aacatgtctt 2700 ctttactatt ccttgcaccc ttcatcccag cctctctttg ctttcacttg gactgaccct 2760 gacacccatc aggctcagca aattacctgg gctgtactcc acaaggcttc acagacagcc 2820 cccattactt tagtcaaacc caaatttctt catcatccat tacctatctc gacataattc 2880 tgcatgaaaa cacacgtgct ctccctgctg atcacgtccg gttaatctcc caaaccccaa 2940 ccccttctac aaaacaacaa ctcctttcct tcctgggcat ggttaggtac ttctgccttt 3000 ggatatctag ttttgccatc ctgactaaac cattatataa actcacaaaa gcaaacctag 3060 ttgaccccac agatcctaaa tcctttccct actccccttt ccattcctta aaaaacagcc 3120 ctaaaagctg ctcccacact ggctctccct aactcatcac tcccttttca ttacatacag 3180 ccgaagtgca gggctgtgtg gtcggagttc tcacacaaga gccgggactg cgccctgtag 3240 cctttctgtc caaacaactt gaccttactg ttttagccta gccctcacgt ctgcgtgcag 3300 tggctgccgc tgccttaata cttttagagg ccctcaaaat cacaaactat gctcaactca 3360 ctctctacag ttctcataac ttccaaaatc tattttcttc ctcacacctg acacatatac 3420 tttctgctcc ccggcttctt cagctgtact cactctttgt tgagtctccc acagttatcg 3480 tcgttcctgg cccggacttc attccagcct cacacattat tctggatacc acacctgacc 3540 cccatgactg tatctctctg atccacctga catccactcc atttccccat gtttccttca 3600 ttcctgttta tcaccctgat cacacttggt ttattgatgg cagttctacc aggcctaatc 3660 accactcacc agcaaaggca agctatgcta tagtatcatt caggctaccg ctctgccccc 3720 ctccactacc tctcagcaag ccaaactgac tgccttaact tgagctctca ctcttgcaaa 3780 gcgactatgc gtcaatattt atactgactc taaatatgcc tttcacatcc tgcaccacca 3840 tgctgttata tgggcagaaa gaaatttcct cactaggcaa gggtcctcca tcattaatgc 3900 ctccttaata aaaactcttc tcaaggcccc tttacttcca aagaaagatg gagtcattca 3960 ctgcaaaggc catcaaaagg catcagatcc cattgctcag gacaatgctt atgctgataa 4020 gatagctaaa aaagcagcta gcgttccaac ttgtatccct cacggcagtt tttctccttc 4080 tcatcgggcc actcccacct actccctcgc tgaaacttcc acctatctct tcccgcacaa 4140 ggcaaatggt tcctggacca aagaaaatat ctccttccaa cctcacaggc ccattctatt 4200 ctgttgtcat ttcataacct cttccatgta ggttacaagc cgctagcctg cctcttagaa 4260 cctctcattt ccttttcatt gtgggaatct atcctcaagg aaatcacttc tcagtgttcc 4320 atctgctatt ctactactcc tcaagaattt ctcaggcccc ctcccttccc tacacatcaa 4380 gttcggggat ttgcccaccc aggactggca aattgacctt actcagatgc ctcgtgtcag 4440 gaaactaaaa taactcttgg cctgggtaga cactttcact ggatgggtag aggcctttcc 4500 cacagggtct aagaagccac tgcagtcatt tcttcccttc tgtcagacat aattcctcgg 4560 tttgggcttc ccacctttat acagtccaat aatggaccag cctttactag tcaaatcacc 4620 caagcagttt ctcaggctct tggtattcag tggtgcctgg ttttacctca aactgccacc 4680 cttaagtctc taagtggata gaagatcttc agtgacaaag taccctccaa cagtttcacc 4740 ctgatgaagt cctgttcttt acttttatgc ttactcttat tctcattccc attcttatgc 4800 caccctctac ctctctccag ctatctccac cacactatca atctcagtca ctctctccta 4860 gccatttcta atcctttttg ctggctttgt atttctcttt cctccaaaat caccaaggta 4920 ttgacttact cactgctaaa aaaaaagggg gactctatgt ttttaaatga agagtgctgt 4980 ttttacctaa atcaatctgg cctggtatat gacgacatta aaaaaaactc aaagatagag 5040 cctaaaagct tgccaaccaa gtaagtaatt acgctaaccc cgcttggacc cccttggaca 5100 ctctaattgg atgtcctggg tcctcccgat tcttagtcct ttaatacctg tttttctcct 5160 tctcttattc ggacctcgta tcttccgttt agtttctcaa ttcatccaaa actgtatcca 5220 ggccatcagc aatcattcta tatgacaaat gtttcttcta acaaccccac aatatcaccc 5280 cttaccacaa aatcttcctt cagcttaatc tctcccactc taggttccca cgccgcccct 5340 aatcccgctc gaagcagcac tgagaaacat cgcccattat ctctccatac aacccccaaa 5400 aattttcgcc accccaacac tttaccacta ttttgtttta tttttcttat taatataaga 5460 agacaggaat gtcaggcctc tgagcctaag ccaagccatc atatccccag tgacctgcag 5520 tatacatcta gatggcctga agtaactgaa gatccacaaa aaggagtgaa aatagcctta 5580 actgatgaca ttccaccat 5599 <210> 85 <211> 6195 <212> DNA <213> Homo sapiens <400> 85 gacagacagg accagctgga tttcctagac taagaattcc taagcctagc tggggaaggt 60 gaccgcgcac ccacctttaa acacggggct tgtaactcag ctcacacctg accaatcagg 120 tagtaaagag ggctcactaa aatacaaatt aggctaaagc aggagataaa gaaacagcca 180 aatcatatat cacctgagag cacaggggga gggacagtga tcgggatgta aacccaggca 240 ttcgagcagg gagcagcaac cccctttggg tcccctccca ttttatggga gctctgtttt 300 cactctatta aatcttgcaa ccgcacactc ttctggtcca tgtctgttac agctcaagcc 360 gagctttcac tcgccatcca ccactgctgt ttgccgccat cgcagacccg ccactgactt 420 ccacccctcc ggatatggca ggatgtcttc tgtgctcctg atccagcaag gcgcccattg 480 ctgctcccaa tcgggctaaa ggctccccat tgttcctgcg tggctaagtg cctgggttct 540 cctaatcgag ctgaacacta gtcgttgggt tccatggttc tcttctgtga cccacagctt 600 ctaatagagc tataacactc accgcatggc ccaaggttcc attccttgga atccatgaag 660 ccaagaaccc caggtcagag aaaaagaggc ttgccaccat cttggaagca gcccaccacc 720 atctcgggag ctctaagaac aaggaccctc ccagtaacat tttggtgacc atgaagggac 780 atccaaagtg gtgagtaata ttggaccact tttacttgct attctgtcct atccctacca 840 tacaaaggtc tgaccagacc taggaggaac tcccttcagg acaggacgat agatggttgc 900 tcccaggtga ttgagaaaaa aaccacaatg ggtattcact aattgatagg gagactcttg 960 tggaagcaga attaggagaa ttgccaaata attggtctgc tcaaacgctg gagctgtttg 1020 cactcagcca agccttaaac tgcttaaaga atcaaaaaac tctatctcaa tcctgactca 1080 aaaggttacc tacaccctct ctgaaacgaa tttgcataag aactgttgtt tgtgggaatg 1140 catcttaatg gggcaactgg gttgttatga aatactctgg aacccacccc agctctagga 1200 ctcaccactg agcacaaagg caatgttggg catgctggta aaggaccact ggagtccagc 1260 agcccagacc cctttctttg tgatcaagga aggtgggaaa aggggtgcag gactgctaca 1320 tggtgagtgt aactaatccg ataagcagag gtccatgggt ggttatgcac cctggaaagg 1380 aataagcatt aagaccatag aggacgctct aggactaatg ctcatcggaa aatgactagg 1440 ggtgctggca tccctgtgat ttttttgttt tgttttttgt tttgtttttt ttttcagatg 1500 ggaagcattc cccctaaggc aaatgcccct aagatgtatt ctggagaatt tggcccagtc 1560 agagtgtatg tacctttttc cctgtcagac ttaaagcaaa ttaaaatagg cctaggtaaa 1620 ttctcaaata accctgatat ctatattgac attttacaag ggttaggaca aaactttaat 1680 ctgacatgag agatataatg ttactgctag atcagacact aaccccaaat aagagaagta 1740 ccaccataac tgcagcccac gagtttggcg atctcgggta tctcagtcag gtcaatgaaa 1800 ggatgacaac agaggaaaga gaacgattct ccacaggcca gcaggcagtt cccaatgtag 1860 accctcattg gaacgcagaa tcagaacatg gagattagtg cagcagacat ttgctaactt 1920 gcgtgctaga aggactaagg aaaactagga agaagcctat gaattattca atgatgtcca 1980 ctataacaca ggaaaaggaa gaaaatccta ctgcctttct ggacagacta agggaggcac 2040 tgaggaagca tacctctctg tcacctgact ctattgaagg ccaactaatt ttaaaggata 2100 agtttatcac tcagtcagct gcagacatta aagaaaaact tcaaaagtcc accttaggcc 2160 cagagcgaaa cttaaaaacc ctattgaact tggcaacctc tgttttttat aatagagatc 2220 aggaggagca ggcggaacgg gacaaacgag gtaagaaaaa ggccaccact ttagtcatgg 2280 ccctcgggca agcggacttt ggaggctctg gaacgcggaa agcctgggca aatcgaatgc 2340 ctaatagggc ttgcttccag tgcggtctcc aaggacactt taaaaaagat tgtccgaata 2400 gaaataaacc gcccccttgt ccatgcccct tatgtcaagg gaatcactgg aaggcccatt 2460 gccccagggg atgaaggtcc tctgagtcag aagccactaa ccagatgatc cagcagcagg 2520 acagagggtg cccggggcaa gcgccagccc atgccatcac cctcacagag ccccgggtat 2580 gtttgaccat tgagggccag gaggttaacc atctcctgga cattggcgtg gccttcttag 2640 tcttactctc ctgtcctgga caactgtcct ccagatctgt cactatctga ggggtcctag 2700 gacagccagt aactagatgc ttctcccagc cactaagttg taactgggga actttactct 2760 tttcacatgc ttttctaatt atgcctgaaa gccccactcc cttgttaggg agagacattc 2820 tagcaaaagc agaggccatt atacacctga acacaggaga aggaacactc gtttattgtt 2880 ccctgcttga ggaaggaatt aatcctgaag tctgggcaac agaaggacaa tatggatgag 2940 caaagaatgc ctctcctgtt caagttaaac taaaggattc cgcccccttt ccctaccaaa 3000 ggcagtaccc ccttagacct gaggcccaac aaggactcca aaagattgtt aaggacctaa 3060 aagcccaagg cctagtaaaa ccatgcagta gcccctctga tactccaatt ttaggagtac 3120 agaaacctaa tggacagtgg aggttagtgc aagatctcag tattatcaat gaggccattg 3180 tccctctata ccaagctgta cctaaccttt acactctgct ttcctaaata ccagaggaag 3240 gagagtggtt tacagtcctg gaccttaagg atgctttttc ctgcatcctg tatatcctga 3300 ctctcaattc ttttttgcct ttgaagatcc ttcgaaccta atatctcaac tcacctggtt 3360 cacggatagc ccccatctaa ttgtccaggc attagcccaa gacttgagcc agttttcata 3420 cctggacact cttgtccttt ggtacatgga tgatttactt ttagccaccc attcagaaac 3480 cttgtgccat caagccaccc aagcactctt aaatttcctt gccacctgtg gctacaagat 3540 ttccaaaaca aaggttcagc tctgctcaca gcaggttaaa tacttagggc taaaagtatc 3600 caaaggcacc agggccctca gtaaggaatg tatccagcct atactggctc atccttatcc 3660 caaaacctta aagcaactaa gagggttcct tggcataaca ggcttctgcc gaatatggat 3720 tcccaggtac ggcgaaatag ccaggccatt gtatacacta attaaggaaa ctcagaaagc 3780 caatacccat ttagtaagat ggacacttga agcagagcag ctttccaggc cctaaagaag 3840 gccctaaccc aagccccagt gttaagcttg ccgacggggc aagacttttc tttgtatgtc 3900 acagaaaaaa acaggaatag ctctaggagt ccttacacag gtccaagaca ccagcttgca 3960 acctgtggca tacctaagta aggaaaatga tgtaacggca aagagttggc ctcattgttt 4020 atgggtagtg gcagcaatag cagtcttagt atctgaagca gttaaaataa tacagggaag 4080 agatcttact gtgtggacat ctcatgatgt aaacggcata ctcactgcta aaggagactt 4140 gttgctgtca ggcaaccgtt tgcttaaata tcaggctcta ttacttaaag ggccagtgct 4200 gtgactgcgc acttgtgcaa ctcttaaccc agccacattt cttccaaacg ataaaagata 4260 gaacataact gtcgacaggt gattgctcaa acctacacca ctcgagggga ccttctagag 4320 tttcccttga ctgatcccaa cctcaacttg tatactaatg gaagttcttt gtagaaaaag 4380 gacttcaaaa agcagggtat gcagtggtcg gtaataatgg aatacttgaa agtaatcccc 4440 tcactccagg aactagcact cagctggcag aactaatagc cctcactagg gcactagaat 4500 taggagaaga aaaaagggta aatatatata cagactgtaa gtatgcttac ctacttctcc 4560 atgaccacgc agcaatatgg agagaaaggg aattcctaat ttcagaggga acacctatca 4620 aacatcggga agccattagg agattattct tggctgtaca gaaacctaaa gagatggcag 4680 tcttacactg ctggggtcat cagaaaggaa aggaaaggga aatagaaggg aactaccaag 4740 cggatattga agccaaaaga gccacaaggc tggaccctcc attagaaatg cttatagaag 4800 gacccctggt atggagtaat cccctcaagg aaacaaagca ccagtactca acagaagaaa 4860 tagattgggg aacctcacaa ggacatagtt tcctcctctc gggagggcta gccaccgaag 4920 aaggaaaaat agttttgcct gcagctaacc aatggaaatt acttaaaacg cttcaccaaa 4980 tctttcactc tcactgcacc tcctccatgc cgctgtacta ccagtagctc cccttaccaa 5040 gagcttctat ggagaaatgt ggcttcccag aaatattgat gccccattgt ataggagttt 5100 ttctaaagga aaccccactt tcactgccca cactcatatg cccttgcact tcaggccata 5160 catttcaatc cctgtatctt taacctcctt gttaagtttg tctcttccag aattgaagct 5220 gtaaaactac aaatggctct tcaaatggag ccccagatgc agtccatgac taagctctac 5280 tgcggacccc tggactggcc tgctagccca tgctctgata ttaatgacat ggaaggcacc 5340 ccccctgagg aaatctcaac tgcacgaccc ctactatgcc ccaattcagc aggaagctgt 5400 taacagcggt cattggccaa cctccccaac agctcttggg ttttcctgtt gagaggggga 5460 actgagagac aggactagct ggatttccta ggccgactaa gaattcctaa gcctagctgg 5520 ggaaggtgac cacacccacc tttaaacacg gggcttgtaa ctcagctgac acccaaccaa 5580 tcaggtagta aagagggctc actaaaatac aaattaggct aaagcaggag gtaaagaaac 5640 agtcaagtca tatatcgcct gagagcacag ggggaaggac agtgatcagg atgtaaaccc 5700 aggcattcga gcagggagtg gcaaccccct ttgggtcccc tcccatttta tgggagccct 5760 gttttcactc tattaaatct tgcaactgca cactcttctg gttcatgttt gttacagatc 5820 aagctgagct ttcactcgcc atccaccact gctgtttgcc gccattgcag acctgccact 5880 gacttccacc cctccggatc tggcaggatg tctgctgtgc tcctgatcca gcgaggtgcc 5940 cattgccgct cccgatcggg ctaaaggctc accattgttc ctgcatggct aagtgcctgg 6000 gttctcctaa tcgagctgaa cactagtcgc tgggttccac ggttctcttc cgtgacccat 6060 ggcttctaat agagctataa cactcactgc atggcccaag gttccattcc ttggaatcca 6120 tgaggccaag aaccccaggt cagactacaa gaggcgggct gccatcttgg gagcagcccg 6180 ccatcatctt gggag 6195 <210> 86 <211> 639 <212> DNA <213> Homo sapiens <400> 86 accccaggaa tgtcaggcaa ccaccaggtg acggtcaggc agttgttaaa ctgtctctct 60 aaaatgataa ttggtcgcgg cccaagccag tgaaaggcag tctcccaaca gatagaaaac 120 acctgaagct ggtgatcagc cgcttcccta taacatctca ggagttggac atatgggctc 180 cagcatgcgc attaagaggc aaaatggtag cgtttaactg gtatatgact tcctagggac 240 attggactgt taagggaaga atacctcaag gaagcataca tacgacttca gtaaacacac 300 tgcacaggct cccctcccaa gtgctaggcc actgtgaatg cagacagccc accccaaggg 360 aagaatcagg gcagaaggga cacaagaccc cagaagtatg ccaacatata aaaccctgag 420 tcaaaggtca aaccacgcac tgatctctca cgctgcccac ttggccctct tccaagtgtt 480 ctttacttcc tttcattcct gctctaaagc tttttaataa actttcactc ctgctctaaa 540 acttgcctcg gtctctcctt ctgccttata cccctcagtt gaattctttc ttctgagagg 600 gcaagaactg aggttgccgt agacccatgc agattcacc 639 <210> 87 <211> 8094 <212> DNA <213> Homo sapiens <400> 87 gtcaggcctc tgagcccaag ctaagccatc atatccccag ggacctgcac gtatacatcc 60 agatggcctg aagcaactga agatccacaa aggaagtgaa aatagcctta actgatgaca 120 ttccaccatt gtgatttgtt tctgccccat cctaactgat caatgtactt tgtaatctct 180 cccaccctta agaaggttct tcgtaattct ttgtaatccc acccttgaga atgtactttg 240 tgagatccac cccctgcctg caaaacattg ctcctaactc caccgcctat cccaaaccta 300 caagaactaa tgataatccc accacacttt gctgactctc tttttggact cagcccgcct 360 gcacccaggt gaaataaaca gccttgttgc tcacacaaag cctgtttggt ggtctcttca 420 cacggatgcg tgtgacgtgc gtgacatttg gtaccaaaga tccgggacgg gagtactcct 480 tacagagacc ggtcccctgt cctcatcctc actccatgag gagatccacg tacaacctcg 540 ggttctcaga ccaaccagcc caaggaacat ctcatgaatt tcaaatcggg taagtggtct 600 tttcactctc ttctccagcc tctctcgcta cccttcagtc tccctgtcct tccaattcca 660 gttctttttc ctctctagta gagacaaagg agacatattt tatccgtgga cccaaaactc 720 cggcgccagt cacggactcg gcaagacagt cttcccctgg tgtttaatga ctgcagggac 780 gcctgcctga ttattcaccc acactccact ggtgtctaat cactgtgggg atgcctgcct 840 tggtcattca cccacattcc cttggtggca agtcaattgc ggggacaacc tgctttggct 900 gctcacccac attgcagccc acggctgctc cctacccccc ttctccgtgt ctctaccctt 960 ctctttaaac tggcctcctt cactgtgggc aacctttcac cctccattcc tccttcttct 1020 cccttagcct gtgttctcaa gaacttaaaa cctcttcaac tctcacttga cctaaaatct 1080 aagcatctta ttttcttctg caacaccgct tggccccagt acgaactcga caatggttct 1140 aaatggccag aaaatggcac ttttgatttc tccatcctgc aagacctaga taatttttgt 1200 cgaaaaatgg gcaaatagtc tgaggtgcct tacgtccagg catttttcag acttcgttcc 1260 ctccctagtc tctgttccca ctgtgactca tcccaaatcc tcctcctttc cctcccgcct 1320 gtcccttcag tcccaacctc gagcgttgct gagtcttgtg aatcttcctt ttctgctgac 1380 ccatctgacc cctcacctcc tccccaggct gctcctcctc agctcgctcc ccgccaggct 1440 gatcaggctc cagctcttct tcagcctctg ctccccaccc tataaccctt ctattacctc 1500 cctcccacac ccggtccggt ttacagtttc tttctgcgac cagctctccc ccatctgccc 1560 aacaatttcc tcatagagag gtggctggag ctgaaggcat atgtcagggt acatgtgcct 1620 ttttctctat cagacctttc ccaaatcagc cagcgtttag gctctttctc atcagacccc 1680 actaaataca tacaggaatt ccgatatcta actctgtcct acagtttaac ctggagtgac 1740 tgaaatgtca tcctaacttc taccctctcc ccagataaat gggaaagagt tttttctcta 1800 gcccaatctc acactgacaa ccaccggctt cacgagccag acctccagga gggcatcaga 1860 gcagttcccc gagaagatcc ccagtggaac taccaggcag attccccagg tatagctacg 1920 cgagattaca tggtttcctg cctagttgaa gggcttaaaa aggcagctta caaagctgtt 1980 aattatgaca aacaagaaac tacccgaggt gaagatgaaa acccagccca gttcatggcc 2040 cacttggcag taacccttag acgctttacc gccctagacc cagaggggcc aggaggccgc 2100 cttattctta atatgcattt tatcacccag tcagctcctg atgttagaaa aaagattcaa 2160 aaactggaat ccagccctca taccccacaa caggaattaa tcaacctcac cttcaaggtg 2220 tacaataata ggaggtagcc agacagcaac gcatttctga gttacagcta ctcgcctctg 2280 ctgtaagaca gcccacaacc acgtctccag catacaagaa cttcagaaca tccaagccac 2340 agctcccagg ggctccttca aaacatcctc gtgggccttg cttcaaatgc caaaagcctg 2400 gccactgggc caaggaatgc ccgcagcctg ggattcctcc taagctgtgc cctgtctgtg 2460 cgcgccccca ctggaggtcg gactgtccga ctcacatcgc cgctgctcct aaagcacctg 2520 gagcccaaac ccaacgttcc ttggccaact ccttcccaga tctcctcggc ttagtggctg 2580 aagactgacg ctgcccatcg cctcgggagc ccctggacca tcacagacac tttgggtaac 2640 tcttacagtg gaggataagt ctgtcccttt cttaatcaat acagaggcta cccactccac 2700 attaaccttt ttttcaaggg cctgtttccc ttgcctccgt aactgttgtg ggtattggcg 2760 gccaggcttc taaacctctt aaattcccca actctggtgc caacttggac aacattcttt 2820 tatgcacccc tttttagtta tccccacctg cccagatccc ttactagatt gagacatttt 2880 aactaaatta tctgcttccc tgactattcc tagcctacaa ccacacctca ttgccaccct 2940 tttctccagt tcaaagccgc cttcacaccc tccccttgga tctccccacc ttaatccaca 3000 agtataggac acctctactc ccaccttggc aaccaatcat gcacccctta ccatcccatt 3060 aaaacctaat cactcttacc ccactcaatg ccaatatccc atcccacagc acactttaaa 3120 aggattaaag cctgttatca ctcgcctgtt atagcatggc cttttaaaac ccataaacac 3180 tccttataat tcccccattt tacctgttcc aaaaactgga caagccttac aggttaattt 3240 cagaatctgc accttatcaa ccaaattgtc ttgcctatcc accctgtggc gccaaagcca 3300 tatactcttc tatcctcaat acctccctcc agaacccctc tacatatatt attatgtaga 3360 tatgtacata tctacatatg tacataatct acataaccca ttctgttctg gatctcaaac 3420 atgctttctt tactattcct ttgcaccctt catcccagcc tctcttcatt ttcacttgga 3480 ctgacccgga cacccatcag gctcagcaaa ttacctgggc tgtactgcca caaggcttca 3540 cggacagccc cccccccccc cgttacttca gtcaagccca aatttcttcc tcatccttta 3600 cctatctcga cttaattctt catgaaaaca cagtgctctc cctgctgatc gtgtctagct 3660 aatctcccaa accccgaccc cttctacaaa gcaacagctc ctttccttcc taggcatggt 3720 tagatactcc gcctttggat acctagcttt accatcctga ctaaaccatc atataaactc 3780 acaaaagcaa acccagctga ccccacagat cctaaatcct ttcgccactc ctctttccgt 3840 tccctgaaaa cagccctaga agctgctccc acactagctc tccctaactc atcccaacac 3900 tttttcatta catacagcca aagtgcaggg ttgtgcagtc agaattctta cacaagagcc 3960 aggaacggcc cctgcagccc ttctgtccaa acaacttgac cttactgttt taggctagcc 4020 cccacattat tcctgatacc acacctgacc ccccatgact gtatctctct aatccaccta 4080 gcatttactc aatttcccca tatttccttc tttcctgttc ctcaccctga tcacacttgg 4140 tttattgatg gcagttccac caggcctaat cgccactcac cagcaaaggc aggctatgct 4200 atagtaactt ccacacctat cattgaggct accactctgc ccccctccac tacctctcag 4260 caagccaaac tcattgcctt aactcaagcc ctcactcttg cagaaggagt acgtgtcaat 4320 atttatactg actctatgcc ttccatagag tcagcatgca ccaccatgct gttatatggg 4380 cagagagagg tttcctcact atgtaagggt cctccatcat taatgcctct ttaataaaaa 4440 ttcttctcaa ggtcgcttta cttccaaagg aatctggagt catttactgc aagagccatc 4500 aaaaggcatc agatcccatc attcagggca acacttatgc tgataagtta gctaaagaag 4560 cagcttagtt ttccaacttc tgtccctcac ggccagtttt tctccttctc atcggtcact 4620 cctacctact ctcccactga aacttccacc tatcaatctc ttcccacaca atgtaaatgg 4680 ttcttagaca aaggaaaata tctccttcca gcctcacagg cccattctat tctatcatca 4740 tttcacaacc tcttccatgt aggttacaag ccgctagcct gtctcttaga acctctcatt 4800 tcctttccat cgtggaaatc tatcctcaag gaaatcactt ctcagtgttc catctgctat 4860 tctactactc ctcaaggatt gttcaggccc cctccctccc tacacatcaa gcgcggggat 4920 ttgcccctgc ccaggaccgg caaattgact ttactcacag gccccgagtc aggaaactaa 4980 aatacctctt ggtctggata gatgctttca ctggatgcgt agaggccttt cccacagggt 5040 ctgggaaggc caccgcagtc atttcttctc ttctgtcaga cataattcct cggtttggcc 5100 ttcccacctc tatacagtct gataacggac cggcctttat tagtcaaatc acccaagcag 5160 tttctcaggc tcttggtatt cagtggaacc ttcatatccc ttaccatctc aatcttcagg 5220 aaaggtagaa gggactaatg gtcttttaca gacacacctc accaagctca gcctccagct 5280 taaaaaggac tggacagtac ttctacctct tgcccttctc agaattagag cctgtcctca 5340 agaagctaca cggtacagtc catttaaact tttatgtgga cgcactttct tgctcagccc 5400 caacctcatc ccagacacca gccctctagg caactatctt ccagtctttc agcaggctag 5460 acaggaaatt cgccaggctg ctaatcttct cttgcctact ccagattccc agccacatga 5520 agacacccta gctggatggt cagttcttgt taataatctg acccctcaaa ctctacaacc 5580 tcgatggacc ggaccctact taaacatcta tagtaccccc aaccaccatc tgcctgcaga 5640 accctcccca ctgggttcac cgttccagaa taaagctgtg tccgtcagac agccagtccg 5700 atatctcctc ttcctcctgg aagtcgcaag tactctcccc tacttccctt aaactcactc 5760 gcatttctga agaacaataa cccttatgag cctaatacat cccttcattc tattaggtct 5820 atccatcctt accctactct tcgcaacagg gctttacgca gtcaccccca ctacttggac 5880 tgtgccccaa aaacctgtca tccctactat cttctgtcta gtcatactcc tattcaccat 5940 tctcaactac tcataaatga cctgctcttg tttacactgc cagtttacat tgtttctcca 6000 agacatcaca gctgatatct cctggtgata tccccaaacc gccactcttg actcctgctt 6060 ggagtggata gatgatcttt ggtggcaggg caccctccaa cacttccacc ctgatgaagt 6120 tctattcttt acttttatat tcactcttat tctcattccc attcttatgc cactctctac 6180 ctctccccag ttacctccag catactatca atctcaccca ctctctcctc actgcctcca 6240 atccttttct agcaaagaat tgttggctac gcgtttccct ttcctcctgc ttttacacag 6300 ccatccctgc tctacaggct gactgggcta cctctcccgt ctccctgcaa ctcagaacct 6360 cctttaataa ccctcatctt tacccgcctg aggaacttct ttattttcta gacagatttg 6420 gtgagaactc cccagacatt tcacaccaac gagctgccac acttctccgc atctacttac 6480 ggcatctttc tccttatgtc aattccactc ctcccatatt tggaccccaa ccacacaaac 6540 aactatccct gttgccgttt ctttatgcat ctcccgacaa cagcctgctg gaatcccttt 6600 aggcaacctt ccaccgtcca aatgttcctt tactctttgt ctccagaacc cagccacaca 6660 cattaccaaa cagatgggag cattccaact tcgcattact gacaagccct ctatcattat 6720 tgacaaacta aaaaacattg gcagtcacta ttgtttagga agacacctac cctgcatctc 6780 accccatcct tggctaccac cctcccctgc tcgtctgaat ctcctcctag cccctcctct 6840 tgcttgctta taccctgccc catgaatagc agcgaaaggt tacttgtaga cactatgcgc 6900 tttctcatac accatgaaaa ccaaacccct ccctctacgc agttgcacca tcaatcccca 6960 ttacaacctc taacggctgc tgcccttgct ggatcgctag gattctggat gcaggattcc 7020 tctttcagta caccctctca ccttttcact ttacatttcc agttctgcct gacacaaggt 7080 ctcttctttt tatgtggctc ttccacctac atgtgcctac ctgccaaatg gatgggcaca 7140 tgtactctag tcttccttac ctccaaaatc cagtttgcag atgggaacga acaactgcct 7200 gtccccctca tgacatcaac acaacaaaaa agagtcatcc cactaatccc tttacttatt 7260 ggtctaggac tttctgcctc cagtattgca cttggaactg gaatagcagg catctcaacc 7320 tctgtcacaa cagtccgcag cctctctaat gacttctctg ctagcactac agatagatca 7380 caaactttat ctgttctcca agcccaggtt aactctttag ctgcagttgt cctccagaac 7440 ggccaaggcc gcgatttact cactgctgaa aaaggaggac tctgtatatt tttaaatgaa 7500 gagtgttgtt tttacctaaa tcaatctggc ctgctatatg acaacataaa aaaactcaag 7560 gatagagccc aaaagctcgc caaccaagca aacaataaca ttgaaccccc ttggacactc 7620 tctaattgga cgtcctgggt actcccaatt cttagtcctt taatacctat ttttctcctt 7680 cttttattcg gaccttgtgt ctttcgttta gtttctcaat tcatataaaa ccgcatccag 7740 gccatcatca gtaattctat atgacaaatg ctccttctaa caaccccaaa atctttcttc 7800 agttgaatct ctcccactgt aggttcccac accgcccctg atcccgctcg aagcagcctt 7860 gagaaacatc gcccattatc tctccatacc acccccaaaa tttgtcactg ctccaacact 7920 tcaccactat tttgttttgc ttttcttatt aatataagaa gacaggaatg tcagccctct 7980 gagcccaagc taagccatca tatcccgtga cctgcatata catccagatg gcctgaagca 8040 actgaagatc cacaaaggaa gtgaaaatag ccttaactga tgacattcca ccat 8094 <210> 88 <211> 2132 <212> DNA <213> Homo sapiens <400> 88 ttatagtggg tagctagtca ggcatgagcg gggcaagaga gggctcccca caacccccac 60 caaaaatgtc aggggctcat caggtgatgt tcaggcagtg ctgtttctct aaaataattg 120 gttgcagcca atgccaggga aaggcagtct cccaacagac agaaaaaacc tgaaactggt 180 gatcagcagc ttcatgataa gatattagga gttgggcgac tgggctcaag catgcacatt 240 gaggcaaaat ggtgtagttg aactggtata tgacctccta gggacatctg actggtaagg 300 gaagaattcc tcaagtgagc atgcctacaa ctccagtaac acactgtgca tgctcccctc 360 ccaagcgcta gcaggccacc atacatgcag acagcccacc ccaagggaag aatcagggga 420 gaacgaacgc aagaccctgg aattatgcaa acatataaaa ccctaagtca aaaggtcaaa 480 ccacgcactg atatttcaag tcacccactt ggccctcttc caagtggact ttccttccct 540 ttgtaacttc tctaaagctt ttaaacaaac tttcattcct gttccaaaac ttgccttgat 600 ctctcctgcc ttccatctcc tcagtcaaat tcttccttct gaggaggcaa gaactgaggt 660 tgctgtagac ctgtatgaat ttgccactgc taacatactt tggtgctata tgactcggat 720 aagttcccta gtagtacaag acctatacac cttgcctgct tcagctggag gcattcaacc 780 cgtctacatg gtttcctcct cctttttgct ctcttgctta ctaaccaacc ccacaaacaa 840 ttcctctcag ctacagtggc tctactcccc ccagctgatc tctcagctta ccctgatggg 900 tagctcacgg gagtgggaag gaccttgggg tccacactga gtagaactaa tggccctcct 960 gggcaggagg ctcatgaaag tggtagggct aaagtctaaa actgtgcaat gtctgggttt 1020 tcctctgctt tttcaactaa aatcagcttt tccccaagaa cctgcactgc ctattcttct 1080 attttctctg tgtgttctga aatggccttg aacacccagc cagacagtct gccttggggg 1140 caagtctggc tctttgcttt cacttcacat gccacatgac ttcttaaaca cacactccct 1200 gttattcatg tgtccgcggc tcttgctgaa ttttcatggc agaaaagaca caggctcctt 1260 tgcagatagc ccctgagatt tatacttgtt tttatcctac cagctcagat gacctccaac 1320 ccttcccctg tctgctggca cattgctggg acagacacta attggaactg tagctctgcc 1380 agctccttat aacttactat atgctttttg ttcctgttac accccagggc caagttttcc 1440 agtggctttt gaagcaattt gtctgcctac ataggacctc actctggccc tttaaggatc 1500 ccacctactt gcctacttgc tttttttttt tttttttttt tttttttttt ttttttttta 1560 gtaagcaccc actgggagga ggataaattc ttcctttgcc atttgcgagt tcttacccca 1620 agccccaagt cccctggagt ttactccttt atgtcaagag ggcaaataaa tgttgccccc 1680 ttgaatccaa gggctgctgt ttttgtgagg atatgaaggc tttccatgag tattcctctt 1740 gcttcctccc acttcctcct gtagcttcca tttctctaac cacttccatg cccttattaa 1800 catacatcaa gaccttcaag gtcatatttg cagggaggga agtctagccc cttggggcag 1860 ttaactgaaa aacaggcttc tcatctactt aaagaacatg gaaatgggaa tataagaaaa 1920 tagataatca ttttgttgct aaatgctgaa gtgagagtca ctatagggtc atggagacaa 1980 ggatataggc tggcccaagg cagcaggtgc aagagaccca ttggacagag atgaagttta 2040 gccctaggct aacagattac cattagaaca gagatgaagg caaggttagg ggtacacagt 2100 aagaccagtt cattccagaa ccttagggac ga 2132 <210> 89 <211> 3389 <212> DNA <213> Homo sapiens <400> 89 gtcaggcctc tgagcccaag ccaagccatt gcatcccctg tgacctgtac atatatatcc 60 agatggcctg aagtaactga agatccacaa aagaagtaaa aatagcctta actgatgaca 120 ttccaccatt gtgatttgtt tccgccccac cctaactgat caatgtactt tgtaattctc 180 cccacccttg agaatgtact ttgtgagatc cacccctgcc cgcaaaacat tgttcttaac 240 ttcaccgcct atcccaaaac ctataagaac taatgataat ccaccaccct ttgctgactc 300 tctttttgga ctcagcccac ctgcacccag gtgaaataaa cagccatgtt gctcacacaa 360 agcctgtttg gtggtctctt cacacagacg cgcatgaaat ttggtgccgt gactcagatt 420 gggggacctc ccttgggaga tcaatccccc gtcctcctgc tctttgctcc atgagaaaga 480 tccacctacg acctcaggtc ctcagaccga ccagcccaag aaacatctca ccaatttcaa 540 atccggtaag tggcctcttt ttactctctt ctccaacctc cctcactatc cctcaacctc 600 tttctccttt cattcttggc gccacacttc aatctctccc ttctcttgat ttcaattcct 660 ttcattttct ggtagagaca aaggagacac attttatctg tggacccaaa actccggcgc 720 tggtcacgga ctgggaaggc agccttccct tggtgtttaa ccattgcagg gacgcctctc 780 tgatcattca cccacgtttc agcggtgtca gaccacgcag ggatgcctgc cttggtcctt 840 cacccttagc agcaagtccc acttttctgg gggaggggca agtaccccag ctccttctct 900 ccatgtctct accccttctc tgattttctg gggcagaggc aagaaccccc caaccccttc 960 tccttcaccc ttagcagcaa gtcctgcttt tctgggggag gggcaagtac cccaaccttg 1020 tatctctgca ccccaatccc ttatttccat gccccaaccc ctttcccgct tttctggagg 1080 gtaagaaccc ccaaacccct tccctccatg tctctatgct cccttttctc tgggcttgcc 1140 tccttcacta tgggcaacct tcctacattc ctccttcttc tcccttagcc tgtgttctca 1200 agaacttaaa acctcttcaa ctcacacctg acctaaaacc taaatgcctt attttcttct 1260 gcaatgccgc ttgacccaat acgaactcga cagtagttcc aaatagccag aaaatggcac 1320 tttgaatttt tccatcctgc aagatctaaa taattcttgt cataaaatag gcaaacggtc 1380 tgaggtgcct gacgtccagg cattctttta cacatcagtc ccttcctagt ctctgtgccc 1440 agtgcaactc gtcccaaatc ttccttcccc tcagtcccaa ccccaagcgt cactgagtct 1500 ttctaatctt ccttttctac agacctatct gacctctccc ctccttgcca ggccgagcta 1560 ggtcccaatt cttcctcagc ctccgctcct ccaccctata atcctatcac ctcccctcct 1620 cacaccaggt ctggcttaca gtttcgttct gtgggaggcc ccacctgccc agcaatttat 1680 tcttaaaaag gtggctggag ctaaaggcat agtcaaggtt aacactcctt tttctttatc 1740 ccaaatcaga tagcgtttag gctctttttc atcaaatata aaaatccagc ccagttcatg 1800 acttgttcgg cagcaaccct gagacacttt acagccctag accctaaaag gtcaaaaggc 1860 cgtcttattc tcaaaataca ttttattacc caatctgctc ccgacattaa ataaaactcc 1920 aaaaattaaa ttctgaccct caaaccccac gacaggattt aattaacctc gccttcgagg 1980 tgtacaataa tagaaaaaag ttgcaattcc ttgcctccac tgtgagacaa accccagcca 2040 catctccagc acacaagaac ttccaaaggc ctgaactgca gcggccaggc gttcctccag 2100 aacctcctcc cccaggagct tgctacaagt gccagaaatc tgaccaccag gccaaggaat 2160 gcctgcagcc caggattcct cctaagccgt gtcccatctg tgcgggaccc cactggaaat 2220 cggactgttc aactcacctg gcagccactc ccagagcccc tggaactctg gcccaaggct 2280 ctctgactga ctccttctcg gcttagcggc tgaagactga cgctgcccga tcgcctctga 2340 agctccacag accatcacgg acaccgagct ttgggtaact ctcacagtgg agggtaagtc 2400 catcccctgt ttaatcgaaa ccgggactat gcactccacg ttgcctactt ttcaagggcc 2460 tgtttccctt gcctccataa ctgttgtggg tattgacggc caagcttcta aacccctgaa 2520 aactccccca ctcttgtgcc aacttggaca acactctttt atgcactgct ttttagttat 2580 ccccacctgc ccagttccct tattaggccg agatatttta accaaattat ctgcttccct 2640 gactattcct ggactacagc tacatctcat tgctgccctt ctccccaacc caaagcctcc 2700 ttcgcgtctt cctctcatat cccccccacc ttaacccaca agtatgggac atctctactc 2760 cttccctggc aactgatcac atgcccgtta ccatcccatt aaaacctaat cacccttacc 2820 ccgctcaacg ccaatatccc atcccacagc acgctttaaa aggattaaag cctgttatca 2880 ctcgcctgct acagcatggg cttctaaaac ctataaactc tccttacaat tcccccattt 2940 tacctgtcca aaaactggac aagtcttaca gattagttca gaatctgcgc cttatcaaca 3000 aaattgtttc acctatccat cctgtggtgc ccaacccgta cactcttttg tcctcaatac 3060 cttcctccac aactcactat tccgttctcg atcttaaaga tgcttttttc actattcccc 3120 tgcacccctc gtcccagcct ctctttgctt tcacttagac tgaccctgac acccattagg 3180 ctcagcaaat tacctgggct gtactgctgc aaggcttcat agacagcccc cattacttca 3240 gtcaagccca aatttcatcc tcatctgtta cctatctcgg cataattatc ataaaaacac 3300 gtgctctccc tgctgatcgt gtccgattaa tctcccaaac ctcaatccct tacaaaacaa 3360 cagctccttt ccttcctagc catggttag 3389 <210> 90 <211> 695 <212> DNA <213> Homo sapiens <400> 90 ttacagtaga tagcgagtca ggcatgagcg gggcaggaga gcctctgcct ccctaggaat 60 atcaggcaac catcaggtga tggccaagca gttattacac tgcttctcta aaataataat 120 tggtcactgc tagtgcgagg gaaaggcagt ctcccagtag aaaaacctga aactgatggt 180 caataggttc ctgataagat ctcaggagtt gggcgagtgg gctcaagcat gcacattaag 240 aggtaaagtg acggagttga actgttcctc gtaggaacat tcagctggta agggaagaac 300 gcctcaagtg agtatgcata caactccagt aaacacactg tgcatagggc ccctcccaag 360 tgctagcagg ccactgtgca tgcagacagc ccaccccaag gcaagaatca ggggagaaag 420 gaaacaagac cccagaagta tgccaacata taaaacccca agtcagaggt caaactgtgc 480 acttgatctc ccaagccacc tgcttggccc tcttccaagt gtacttagct tcctttcatc 540 cctgccctaa aacgttttaa taaactttca ctcctgctct aaaacttgcc ttggtctgtc 600 actctgcctt atgacccctc ggttgaattc tttcttctga ggaggcaaga attggggctg 660 atgcagacct gtatggattc accaccgcta acata 695 <210> 91 <211> 7330 <212> DNA <213> Homo sapiens <400> 91 ctttgggtcc cctcccttcg tatgagagct ctgttttcac tctattaaat cttgcaactg 60 cactgttctg gtccgtgttt gttacagctc aagctgagct tttgctcgcc gtctaccact 120 gctgtttgcc gccatcgcag actcgctgct gacttccatc tctccagatc cggtaaggtg 180 tctgctgtgc tcctgatcca gtgaggcacc cattgctgct cccgattggg ctaaaggctt 240 gccattgttc ctgcatggct aagtgcccgg gttcatccta atcgagctga acactagtca 300 ctgggttcca tggttctctt ccataaccca tggcttctaa tagagctata acaatcaccg 360 catggcccaa gattccattc cttggaatcc gtgaggccaa gaaccccaga tcagagaaca 420 tgaggcttgc caccatcttg gaagcagccc gccgccatct tgggagctct gggagcaagg 480 accccaggta acatttggtg accacgaagg gacttccaaa gcggtgagta atattagacc 540 actttcactt gctattctgt cctattcttc cttagaattg gaggaaaata ctgggcacct 600 gtcgtccggt tcgtctgtct ggagccagct tccactttca attttcttgg agaaaccaag 660 ggccgactag aggcagaaag ctgtcatccc gaactcctga cattagccgg ttgagatcat 720 ggcacagcca gaagtctcta cagtcgccca tgcgtgtgcc cctacctttc cctctgaccc 780 atacctcctg ggtcccgacc acgactttct tgaaagtgta gccccaaaat tctccttacc 840 tctgaatctg cttcctctga tccctgcctc ctaggtacta atggttcaga ctttcatttc 900 ctctagcaag ctgtatctcg aaagggatct aaggaagctc tacgctgtgt cctgaggcat 960 ctagacataa acccagggag tcttatccct ggtgtccctc ctgatttagg tatacagctc 1020 tcgatatggg cagttatgtg ggacccgttc cccaccaccc ttgccagggc cccaagtttg 1080 taatggctaa gagaagagaa agagtgacag aggagagaga gatggaagag agaaagagag 1140 atggaagaga gagagagaga gagagatgga ggagagacag aggagagaga gacagaggag 1200 agacagagga gatagagaga gagagataaa gagggagtca aagagaaaaa gaaaaagaca 1260 gaaatagtaa acaaacaaac aaacaaaaac cagtgtgccc tattccttta aaagccaggg 1320 taaatttaaa acctatgatt gataattgaa ggtcttctcc ctgaccctat aacattccaa 1380 taccactttg ttgtcagtgt aaataagggc gtagccgaaa gcactgaggc caccgacaac 1440 cagtagcctt cctatcaaaa atccttaacc caggaacccg cgggtggccc aaatgcattc 1500 aatctgtagc agcaactgct ttgctaacag aagaaagtag aaaattagcc tttagaggaa 1560 acctcattgt gagcacacct caccagttca gaactatcgt aagtcaaaaa agcaaacagg 1620 tagcttacta actcaaaaat cttaaagtat gggtctattc tgttagaaaa aggtaattta 1680 acaccaacca ctgataattc ccttaaccca gcagatttcc taacagggga tttaaatctt 1740 aattaccata caaaggtccg accagaccta ggaggaactc ccttcaggac aggacacagg 1800 gtctcgctct gtcacccagg ctggagtgca gtggtacaat tatggcgctc actgcaactt 1860 caactttcca ggcccaagca atccaccccc ctcaccccca caattagttg agggtacagg 1920 tgtgtgccac catacctggt taatttttct ttactttttg tatagacagg atctcactgt 1980 gttgcccagg ctggtcgcaa actcctgggc tcaagcgatc ctcctgtctt ggcctcccaa 2040 agtgctagga ttacagatgt gagccaccac acctggccct gaccgataga tggttcctcc 2100 caggagactg agggaaaaac cacaacgggt attcagtaat tgatagggag actcttgtgg 2160 aagcagagtt agaaaaattg cctaataatt ggtctcctca aacgtgggag ctgtttgcac 2220 ttagccgagc cttaaagtac ttacagaatc aaaaaagact atctcaatcc tgactcaaaa 2280 ggttacccac accctctctg aaacaaattt gcataagaac tgttgtttat gggaatgaat 2340 cttgatgggg cagctgggtt gttatgaaat actcaggaac ccagcccagc tctaggactc 2400 acccctgagc acaaatgcaa tgttgggcac gctggtaaag gaccactaga atccagcagc 2460 ccggacccat ttctttgtgg tcaagaaaga cggaaaaagg ggtgcaggac tgctacatcg 2520 gtaagcgtaa ctaatccgat aagcagaggt ccatgggtgg ttacgcaccc tggaagggaa 2580 taaacattag gaccatagag gacgctctag gactaatgct catcagaaaa tgactagggg 2640 tgctggcatc cctatgttct tttttcagat gggaaacatt ccccccaagg caaaaacgcc 2700 cctaagatgt attctggaga attgggacca atttgaccct cagatgctaa gaaagaaact 2760 acttatattc ttctgcagta ctgcctggcc acaatatcct cttcaagggg gagaaacctg 2820 gcctcctaag agaagtataa attataacag catcttacag ctagacctct tttgtagaaa 2880 agaaggcaaa tggagtgaag tgccatatgt gcaaactttc ttttcattaa gagacaactg 2940 gcaattatgt aaaaagtgtg atttatgccc tacaggaagc cctcagagtc tacctcccta 3000 ccccagtgtc cccctgactc cttccccaac taataaggac cccccttcaa cccaaatggt 3060 ccaagaggag atagacaaag gggtaaacaa tgaaccaaag agtaccagta ttccccgatt 3120 atgccccctc caagcagtag gaggaggaga attcggccca gccagagtgc atgtaccttt 3180 atctctctca gacttaaagc aaattaaaat agacctaggt aaattctcag ataaccctga 3240 tggctatatt gatgttttag aagggttagg acaatccttt gatttgacat ggagagatat 3300 gttactgcta aatcagacac taaccccaaa tgagagaagt gccgccataa ctgcagcccg 3360 agagtttggt gatctctggt atctcagtca gctcaatgat aggatgacaa cagaggaaag 3420 agaatgattc cccacaggcc agcaggcagt tcccactgta gaccttcatt gggacacaga 3480 atcagaacat ggagattggt gccgcagaca tttgctaact tgcgcgctag aaggactaag 3540 gaaaactagg aagaagccta tgaattattc aatgatgtcc actataacac agggaaagga 3600 agaaaatcct tctgcctttc tggagagact aagggagaca ttgaggaagc atacctccct 3660 gtcacctgac tctattgaag gtcaactaat cttaaaggat aaatttttca ctcagtcagc 3720 tgcagacatt agaaaaaaac ttcagaagtc ctccttaggc ctggagcaaa acttagaaac 3780 cctattgaac ttggcaacgt tggtttttta taatagagat caggaggaac gggacaaacg 3840 ggataaaaaa aaaagggcca ccgctttagt catggccctc aggcaagcgg actttggagg 3900 ctctggaaaa gagaaaagct gggcaaatcg aatgctaata gggcttgctt ccagtgcggt 3960 ctacaaggac actttaaaaa agattgtcca agtagaagta agccaccccc tcgtccatgc 4020 cccttatgtc aagggaatca ctggaaggcc cactgcccca ggggacgaag gtcctctgag 4080 tcagaagcca ctaaccagat gatccagcag caggactgag ggtgcccggg gcaagtgcca 4140 gcccatgcca tcaccctcac agagccccag gtatgctaga ccattgaggg ccaggaggtt 4200 aactgcctcc tggacactgg cacagccttc tcagtcttac tctcctgtcc cggacaactg 4260 tcctccagat ctgtcactat ccgaggggtc ctaggacagc cagttactag atacttctct 4320 cagccactaa gttgtgactg gggagcttta ctgttttcac atgcttttct aattatgcct 4380 gaaagcccca ctcccttgtt agggagagac attctagcaa aagcaggggc cattatacac 4440 ctgaacatag gagaaggaac actcgtttgt tgtcccctgc ttgaggaagg aattaatcct 4500 gaagtctggg caagagaagg acaatatgga cgagcaaaga atgcccgtcc tgctcaagtt 4560 aaactaaagg agcccgcctc ctttccctac caaaggcagt acccccttag acccgaggcc 4620 caacaaggac tccaaaagat tgttaaagac ctaaaagccc aaggcctagt aaaaccatgc 4680 aatagcccct gcaatgctcc aattttagga gtacagaaac ccaacggaca gtggaggtta 4740 gtgcaagatc tcaggattat caatgaggcc gttgtccctc tatacccagc tgtacctaac 4800 ccttatactc tgctttccca aatgccagag gaagcagagt agtttacagt cctggaccta 4860 aagggtgcct tttgtgcatc cctgtacatc ctgactctca attcttgttt tcctttgaag 4920 atccttcgaa cccaacgtct caactcacct ggactgtttt accccaaggg ttcagggata 4980 gcccccatct atttggccag gcattagccc aagacttgag ccagttctca tacctggacc 5040 ctcttgtcct ttggtacgtg gtgatttaat tttagccact cgttcagaaa ccttttgcca 5100 ctaagccacc caagcactct taaatttcct cgccatctgt ggctacaaag tttccaaacc 5160 aaaggctcag ctctgctcac aacaggttaa atacttaggg ttaaaattat ccaaaggcac 5220 cagggccctc agtgagaaac gtatccagcc tatactggct tatcctcatc ccaaaacact 5280 aaagcaacta agaggattcc ttggcataac aggcttctgc caaatgtggt ttcccaggta 5340 cggcgaaata gccaggcctt tatatacact aattaaggaa actcagaaag ccaataccca 5400 tttagtaaga tggacacttg aagcagaagc agctttccag gccctaaaga aggccctaac 5460 ccaagcccca gtgttgagct tgccaacaag gcaagacttt tctttatatg tcacagaaaa 5520 aaccggaata gctctaggag tccttacaca ggtccgaggg atcagcttgt aatctgtggc 5580 gtacctgagt aaggaaattg atgtagtggc aaagggttgg cctcattgtt tactggtagt 5640 ggcagcagta acagtcttag tatctgaagc agttaaaatg atacaggaag agatcttact 5700 gtgtggacat ctcatgatgt gaatggcata ctcactgcta aaggagactt gtggctgtca 5760 gaaaaccgtt tacttaaata tcaggctcta ttacttgaag ggccagtgct gcgactgtgc 5820 acttgcgcaa ctcttaatcc agtcacattt cttccagaca atgaagaaaa aaatagaact 5880 taactgtcag caagtaattg ctcaaacctg cgccgctcga ggggaccttc tagaggttcc 5940 cttgactgat ccccacctca acttgtatac tgatggaagt ccctttgtag aaaaaggact 6000 tcgaaaagca gggtatgcag tggtcagtgg taatggaata cttgaaagta attccctcac 6060 tccaggaact agcgctcagc tggcagaact aatagccctc acttgggcac taaaattaag 6120 ggaagaaaaa aggtaaatat atatacagac tcttaagtat gcttacctag tcctccatgc 6180 ccatgcagca atatagagag aaagggaatt cccaacttcc gagggatcac ctatcaaaca 6240 tcaggaagcc attaggagat tattattggc tataaagaaa cctaaagagg tggcagtctt 6300 acactgccaa ggtcatcaga aaggaaagga aagggaaaca gaagggaatc gccaagcaga 6360 tattgaagcc aaaagagccg caaggcagga ccctccatta gaaatgctta tagaaggacc 6420 cctagtgtgg ggtaatcccc tccaggaaac caagccccgg tactcagaag aagaaataga 6480 atggggaacc tcatgaggac atagtttcct cccctcagga tggctagcca ccaagaagga 6540 aaaatacttt tgcctgcagc taaccaatgg aaattactta aaacccttca ccaaaccttt 6600 cacttaggca ttgatagcac ccatcagatg gccaaatcat tatttactgg accaggcctt 6660 ttcaaaacta tcaagcagat agtcagggcc tgtgaagtgt ggcaaagaaa taatctcctg 6720 cactgcaggc catatatttc aatccctcta tctttaacct ccttgttaag tttgtctctt 6780 ccagaatcga agctgtaaaa ctacaaatca ttcttcaaat ggagccccag atgcaatcca 6840 tgactaagat ctactgcgga cccctggacc ggcctgctag cccatgctcc aatgttaatg 6900 acattgaagg cacccctcct gaggaaatct caactgtaca acccctacta tgccccagtt 6960 cagcaggaag cagttagagt ggttgttggc caacctcccc aacagcactt gggttttcct 7020 gttgagaggg gggactgaga gacaggacta gctgaatttc ctaggccaac taagaatccc 7080 taaggctagc tgggaaggtg accacgtcca cctttaaaca cggggcttgc aacttagctc 7140 acatctgacc aatcagagag ctcagtaaaa tgctaattag gcaaaaacag gacgtaaaga 7200 aatagccaat catcttatca cctgagagca caatgggaag gacaatgatc gggatgtaaa 7260 cccaagcatt cgagccagca acagctaccc tctttgggtc ccctcccttt gtatgggagc 7320 tctgtcttca 7330 <210> 92 <211> 5300 <212> DNA <213> Homo sapiens <400> 92 gtcagggcct ctgagcccaa gccaagccac tgcatcccct gtgacttgca catataccgc 60 ccagatggcc tgaagtaact gaagaatcac aaaagaagtg aaaatgccct gccccacctt 120 aactgatgac attccaccaa aaaagaagtg taaatggccg gtccttgact taagtgatga 180 cattaccttg tgaaagtcct ttttctggct catcctggct caaaaactcc cccactgagc 240 accttgctac ccccactcct gcccgccaga gaacaaaccc cctctgactg taattttcct 300 ttacctgccc aaatcttata aaatggcccc acccctatct ccctttgctg actctctttt 360 cggactcagc ccgcctgcac ccaggtgaaa taaacagcca tgttgctcac acaaagcctg 420 tttggtggtc tcttcacatg gacgcgcatg aaatttggtg ccatgactcg ggtcagggaa 480 cctcccttgg gagatcaatc ccctgtcctc ctgctctttg ctccgtgaga aagatccacc 540 tacgacctca agtcctcaga ccgaccagcc caagaaacgt ctcaccaatt tcaaatccgg 600 taagtggcct ctttttactc tcttctccaa cttccctcac tacccctcaa ccccttctcc 660 ttcaccctta gcggcaagtc ccgcttttct aggggacaag aacccccaat cccttatttc 720 cacgccccga cccctttccc gcttttctgg agggtaagaa cacttgaacc ccttccctcc 780 atgtctctat gctctctttt ctctgggctt gcctccttca ctatgggcaa ccttccaccc 840 tccattcctc cttcttgtcc cttagcctgt gttcttaaga acttaaaacc tcttcaactc 900 tcacctgacc taaaatctaa gcgtcttatt ttcttctgca atgccgcttg accccaatac 960 aaactcgaca gtagttccaa atagccggaa aacagcactt tcaatttttc catcctgcaa 1020 gatctaaata attcttgtca taaaatagac aaatggtctg aggtgcctga cgtccaggca 1080 ttcttttaca catcagtccc ttcctagtct ctgtgcccaa tgcaactcat cccaaatctt 1140 ccttctttac ctcctgcctg tcccctcagt cccaacccca agcatcactg agtctttcta 1200 atcttccttt tctacagacc cgtctgacct ctcccctcct cgccaggctg agctaggtcc 1260 caattcttcc tcagcctctg ctcctccacc ctataatcct tttatcacct cccatcctca 1320 caactggtcc ggcttacagt tacgtttcgt gactagccct cccccacctg cccagcaatt 1380 tactcttaaa aaggtggctg gagctaaagg catagtcaag gttaatgcta cttttcttta 1440 tcagacctct cccaaatcac tgagcattta ggctttttca tcaaatatga aaaacccagc 1500 ccagttcatg gctcgttcgg cagcaaccct gagacgcttt acagccctag accctaaaag 1560 gtcaaaaggc catcttattc tcaatataca ttttattacc caatctgctc ccaacattaa 1620 ataaaactcc aaaaattaga atctggccct caaaccccac aacaggactt aattaacctc 1680 accttcaagg tgtacaataa tagaaaaaag ttgcaattcc ttgcctccac tgtgagacaa 1740 accccagcca catctccagc acacaagaat ttccaaacgc ctgaaccgca ctggccaggc 1800 gttcctccag aacctcctcc cccaggagct tgctacaagt gccagaaatc tggccaccag 1860 gccaaggaat gccctcagcc caggattcct cctaagccgc gtcccatctg tgtaggaccc 1920 cactggaaat cggactgttc aactcacctg gcagccactc ccagagcccc tggaactctg 1980 gcccaaggct ctctgactcc ttctcggctt agcggctgaa gactgatgct gcccgatcac 2040 ctcagaagcc ctgtagacca tcacggatgc caagctttag gtaactctca cagtggaagg 2100 taagcccatc cccttcttaa tcaatatgga ggctacccac tccacattac cttcttttca 2160 agggtctctt tcccttgcct ccataactgt tgtgcgtatt gacagccagg cttctaaacc 2220 tcttaaaact ccccaactct cgtgccaact tagacaacac tcttttaagc actccttttt 2280 aattatcccc acctgcccag ttcccttatt aggctgagac actttaacta aattatctgc 2340 ttccctgact gttcctggac tacagctgca tctcattgcc acccttctcc ccaacccaaa 2400 gcctcctttg tgtcctcttt tatccccccg accttaaccc acaagtataa gacacctcta 2460 ctccctcctt ggtgacccat catgcacccc ttaccatctc attaaaacct aatcaccctc 2520 accctgctca aagccaagat cccatcccac agcacgcttt aaaaggatta aagcctgtta 2580 tcactcgcct gctacggcat ggccttttaa agcctataaa ctctccttac aattccccca 2640 ttttacctgt cctaaaacca gacaaggctt acaagttagt tcagaatctg tgccttatca 2700 accaaattgt tttgtctatc cacctcgtgg tgccaaaccc atatactctc ctatcctcaa 2760 tacctccctc tactacccat tattctgttc tggatctcaa acatgctttc tttactattc 2820 ctttgcaccc ttcatcccag cctctctttg ctttcactta gactaccctg acacccatca 2880 agctcagcaa attacctggg ctgtactgcc acaaggcttc acagacagcc cccattactt 2940 cagtgaggcc caaatttcat cctcatctgt tacctatctc ggcataattc tcataaaaac 3000 acacatgctt tccctgctga tcgtgtccaa ttaatctccc aaacctcaat cccttacaaa 3060 acaacaactc ctttccttcc taggcatggt tagtgcagtc agaattctta cacaagagcc 3120 aggaccacac cctgtaacct ttctgtccaa acaacttgac cttactgttt tagcctagcc 3180 ctcatgtctg cgtgcagtgg ctgccactgc tttaatactt ttaaaggccc taaaaatcac 3240 aaactatact caactcactc tccacatttc tcataacttc caaaatctat tttcttcctc 3300 atacctgacg catatacttt ctgctcccca gctccttcag ctgtactcac tctttgttaa 3360 gtcccacaat taacattgtt cttggcccgg acctcaatct ggcctcccac attattcctg 3420 ataccacacc tgacccccat gactgtatct ctctgatcca cctgacattc accccatttc 3480 cccatatttc cttctttcct gttcctcacc ctgatcacgc ttgatttatt gatggcagtt 3540 ccaccaggcc taatcgccac acaccagcaa aggcaggcta tgctatagta caagccacta 3600 gcccgcctct tagaacctct cattgccttt ccatcatgga aatctatcct caaggaaata 3660 acttctcagt gttccatctg ctattctact actcctcagg gattattcag gccccctccc 3720 ttccctacac atcaagcttg aagatttgcc cccatccagg actggcaaat tagctttact 3780 caacatgccc cgagtcagat aactaaaata cctcttagtc taagtagaca ctttcactag 3840 ataagtagag gcctttccta cagggtctga gaaggccacc acagtcattt cttcccttct 3900 gtcagacata attcctcatt ttagccttcc cacctctata cagtctgata acagaccagc 3960 ctttattagt caaatcagcc aagcagtttt tcaggctctt agtattcagt gaaaccttta 4020 tatcccttac agtcctcagt cttcaggaaa agtagaacag actaatggtc ttttaaaaac 4080 acacctcacc aagctcagcc accagcttaa aaaggactgg acaatacttt aaccactttc 4140 gcttctcaga attcaggcct gtcctcggaa tgctacaagg tacagcccag ttaagctcct 4200 gtatagacgc tcctttttat taggccccag tctcattcca gacaccagac caacttagac 4260 tgtgccccaa aaaacttgtc atccctacta tcttctgtct agtcatactc ctattcaccg 4320 ttctcaacta ctcatacatg ccctgctctt gtttacactg ccagtttaca ctgtttctcc 4380 aagccatcac agctgatatc tcctggtgct atccccaaac cgccactcta aactcttgag 4440 gtaaataaat aatctttgct ggcaggacta tgctgaacct ccttaggcac tctccaatca 4500 gatgtcctgg gtcctcccaa ttcttagacc ttttatacct gtttttctct ttctcttatt 4560 ccatttagtt tttcaattca tataaaaccg tatccaggcc atcaccaatc attctacaca 4620 acaaatgttt cttctaacaa ccccacaata tcacccctta ccacaaaatc ttccttcagc 4680 ttaatctctc ccaccccagg ttcccacgcc gcccctaatc ccgctcaaag cagccctgag 4740 aaacatcgcc cattctctct ctccatacca ccccccaaaa atttttaccg ccccaatact 4800 tcaacactat tttgttttat ttttcttatt aatataagaa ggcaggaatg tcaggcctct 4860 gagcccaagc caagccattg catcccctgt gacttgcatg tatacgccca gatggcctga 4920 agtaactgaa gaatcacaaa agaagtgaaa atgccctgcc ccaccttaaa tgatgacatt 4980 ccaccacaaa agaagtgaaa atggccggtc cttgccttaa gtgatgacat taccttgtga 5040 aagtcctttt cctggctcat cctggctcaa aaagctcccc cactgagcac cctgcgaccc 5100 ccactcctgc ccgccagagg acaaaccccc tttgactgta attttccttt acctgcccaa 5160 atcttataaa acggccccac cccatctccc ttcgctcact ctcttttcgg actcagcccg 5220 cctgcaccca ggtgaaacaa acagccatgt tgctcacaca aatcctgttt ggtggtctct 5280 tcacacggac gtacatgaaa 5300 <210> 93 <211> 5242 <212> DNA <213> Homo sapiens <400> 93 gtcaggcctc tgagcccaag ccaagccatc gcatcacctg agacttgcag gtatacatcc 60 agatggcctg aagtaactga agatccacaa aagaagtaaa aatagcctta actgatgaca 120 ttccaccatt gtgatttctt cctgccccac ctaactgatc aatgtacttt gtaatctccc 180 ccacccttaa gaaggttctt tgtaattctc cccacccttg agaatgtact gtgtgagatc 240 cacccctgcc cgcaaaacat tgttcttaac ttcaccgcct atcccaaaac ctctcagaac 300 taatgataat ccaccaccct ttgctgactc tcttttcgga ctcagcctgc ctgcagccag 360 gtgaaataaa cagccatgtt gctcacacaa agcctgtttg gtggtctctt cacacggacg 420 cgcatgaaat ttggtgccgt gactcggatc gggggaccga cctcccttgg gagatcaatc 480 ccccatcctc ctgctctttg ctctgtgaga aagatccacc tacgacctca ggtcctcaga 540 cagaccagcc caagaaacaa ctcaccaatt tcaaatccgg taagcggcct ctttttactc 600 ttttccaacc tccctcacta tctctcaacc tctttctcct ttcaatcttg gcgccacact 660 tcaatctctc ccttctctta atttctattc cttttgtttt ctggtagaga caaaggagac 720 acgttttatc tgtggaccca aaactctggc gccggtcacg gactgggaag gcagccttcc 780 cttggtgttt aatcattgca aggacgcctc tctgattatt cacccacgtt tcaaaggtgt 840 cagaccacgc agggacgcct gccttggtcc ttcatccttg gtggcaagtc ccgcttttct 900 gggggagggg caagttcccc aaccccttct ctgtgtctct accccttctc tgcttttctg 960 gggaagggac aagtacccat caaccccttc tccttcaccc ttagtggcaa gtcccgcttt 1020 tctaggggtc aagaaccccc aatcccttat ttccgcaccc caacctctta tctctgtgcc 1080 ccaatccctt atttccatgc cccgaccccg cttcctgctt ttctggaggg taagaaccct 1140 gaaccccttc cctccgtgtc tctacgctct cttttctctg ggtttgcctc ctttactatg 1200 ggcaaacttc caccctccat tcctccttct cccttagcct gtcttctcaa gaacttaaaa 1260 cctcttcaac tcacacctga cctaaaacct aaacgcctta ttttcttctg caatgctgct 1320 tgaccccaat acaaactcga tagtagttcc aaatagccag aaaatggcac tttgaatttt 1380 tccatcctgc aagatctaaa taattcttgt cataaaatag gcaaatggtc tgaggtgcct 1440 gacgtccagg cattctttta cacatcacag tcccttccta gtctctgtgc ccaatgcaac 1500 tcgtcccaaa tcttccttct ttccctccca cctgtcccct cagtcccaac cccaagcgtt 1560 gctgagtgtt tctaatcttc cttttctaca gacccaactg acctctcccc tcctcgccag 1620 gccaagctag gtcccaattc ttcctcagcc tccgctcctc caccctataa tcgtttcatc 1680 acctcccctc ctcacacccg gtatggttta cagtttcgtt ccgtgactag cccttcccca 1740 cctgcgcagc aatttattct taaaaaggtg gctggagcta aaggcatagt caaggttaat 1800 gctccttttt ctttatccca aatcagatgg cgtttaggct ctttttcttc aaatataaaa 1860 atccagccca gtacatggct cgtttgacag caaccctgag acgctttata gccctagacc 1920 ctaaaaggtc aaaaggccgt cttattctca atatacattt tattacccaa tctgctcctg 1980 acattaaata aaactccaaa aattggaatc tggctctcaa accccacaac aggacttaat 2040 taacctcgcc ttcaaggtgt acaataacag aaaaaaagtt gcaattcctt gcctccactg 2100 tgagacaaac cccagccaca tctccagcac gcaagaactt ccaaacgccc gaaccgcagc 2160 agccaggcgt tcctccagaa cctcctcccc caggaacttg ctacacatgc tggaaatctt 2220 ggccactggg ccaaggaatg cccgcagcct gggattcctc ctaggccgcg tcccatctgt 2280 gtgggacccc actgaaaatc ggactgttca actcacctgg cagccactcc cagagcccct 2340 ggaactctgg cccaaggctc tccgactgac tccttctcgg cttggcggct gaagactgac 2400 gctgcccgat cacctcgaaa gccccgtaga ccatcacaga cgccgagctt cgagtaacta 2460 tcacagtgga agataagtcc gtccccttaa tcaatacaga ggctacccac tccacattac 2520 cttcttttca agggcctgtt tcccttgctt ccataactgt tgtgggtatt gacagccagg 2580 cttctaaacc tcttaaaact ccccaactct ggtgccaact tagacgatac tctttaaagc 2640 actcctttta gttatctcca cctgcccagt tcccttatta ggccgagaca ctttaactaa 2700 atcatctgct tccctgacta ttcctggatt acagctacat ctcattgctg cccttcttcc 2760 caatccaaag cctcctttgc gtcctcctct tgtattcccc caccttaacc cacaagtata 2820 agatacctct actccttcct tggcaaccga tcatgcaccc cttaccatct cattaaaacc 2880 taatcaccct taccctgctc aatgggtaag gccttttaag cctataaact ctccttacaa 2940 ttcccccatt ttacctgtcc taaaaccaga caagccttac aagttagttc aggatctgtg 3000 ccttatcaac caaattgttt tgcctatcca ccccatggtg ccaaacccat atactctcct 3060 atcctcaata cctccctcca caacccatta ttctgttctg gatctcaaac atgctttctt 3120 tactattcct ttgcacccgt catcccagcc tctcttcgct ttcacttgga ctgaccctga 3180 cacccattag gctcagcaaa ttacctgggc tgtactgccg caaggcttca cagacagccc 3240 ccattacttc agtcaagccc aaatttcatc ctcatctgtt acctatctca gcataattct 3300 tcataaaaac acacgtgctc tccctgctga tcgtgtccaa ttaatctccc aaacctcaat 3360 cccttacaaa acaactcctt tccttcctag gcatggttag tgtggtcaga attcttacac 3420 aagagccagg accgcaccct gtagcctttc tgtccaaaca acttgacctt actgttttag 3480 cctagccctc atgtctgcat gcagcggctg ccgctgcttt aatactttta gagccctaaa 3540 aatcacaaac tatgctcaac tcactctcta catttctcat aacttccaaa atctattttc 3600 ttcctcatac ctgacgcatg tactttctgc tccccggctc cttcagctgc actcactctt 3660 aagtcccaca attaccattg ttcctggccc ggacttcaat ctggcctccc acattattcc 3720 tgataccaca cctgaccccc atgactgtat ctctctgatc cacctgatat tcaccccatt 3780 tccccatatt tccttctttc ctgttcctca ctctgatcac gcttgattta ttgatggcag 3840 ttccaccagg cctaatcgcc acacaccagc aaaggcaggc tatgctatag tacaagccat 3900 gagcccgcct cttagaacct ctcatttcct ttccatcgtg gaaatctgtc ctcaaggaaa 3960 tcacttctca gtgttccatc tgctgttcta ctactcctca gggattattc aggccccctc 4020 ccttccctac acatcaagct cagggatttg cccccaccca ggactggcaa attagcttta 4080 ctcaacatgc cccgagtcag gaaaccaaaa tacctcttag tctaggcaga cactttcact 4140 ggataggtac aggccttttc tacaaggtct gagaaggcca ccgcagtcat ttcttccctt 4200 ctgtcagaca taattcctca gtttagcctt cccacctcta tacagtctga taacagacca 4260 gcctttatta gtcaaatcag ccaagcagtt tttcaggctc ttagtattca gtgaaacctt 4320 tatatccctt acggtcctct gtcttcaaga aaagtagaac ggactaaagg tcttttaaaa 4380 acacacctca ccaagctcag ccaccaactt aaaaaggact ggacaatact tttacctctt 4440 ttgcttctca gaatgctgca gggtacagcc tatttgagct cctgtatgga caatcctttt 4500 tattaggccc cagtctcatt ccagacaccg gaccaactta gactgtgccc caaaaaaact 4560 tgtcatccct actattttct gtctagtcat actcctattc tccgttctca actactcata 4620 cgtgccctgc tcttgtttac actgctggtt tacactgttt ctccaagcca tcacagctga 4680 tatctcctca tgctatcccc aaactgccac tcttaactcc tgaagtaaac aaataatctt 4740 tgctggcagg actatgctga atctccttag gcactctcta atcagatgtc ctaggtcctc 4800 ccaattctta gaccttttat acctgttttt ctccttctct tattccattt agtttttcaa 4860 ttcatacaaa actgtaccca ggccatcacc aatacttcta cacaacaaat gtttcttcta 4920 acaaccccac aatatcaccc cttaccacaa aatcttcctt cagcttaatc tctcccactt 4980 taggttcgca cgccgcccct aatcctgctt gaagcagccc cgagaaacat cgcccattct 5040 ctctccatac caccccccaa gacttcaaca ctattttgtt ttatttttct tattaataaa 5100 agaaggcaga aatgtcaggc ctctgagccc aagccaagcc atcgcatcac ctgtgacttg 5160 cacgtataca tccagatggc ctgaagtaac tgaagatcca caaaagaagt aaaaatagcc 5220 ttaactgatg acattccacc at 5242 <210> 94 <211> 295 <212> DNA <213> Homo sapiens <400> 94 tgggtcaggc acaaagtaag cccaccacac taggaaatat gtggaaaaat ttcaagaaaa 60 gatttaaggg agactatgga gtactatgac accaggaaaa cttaaaactt tgtgtaaggt 120 agactggcca gcattagagg tggccatcag aaggaagcct ggacaggtcc cttgtttcaa 180 aggtatggca caaggtaact tgtaagccag ggcacccaga ccagttccca tacatagaca 240 cttggttaca gctggtttta gaccaccccc cacagtggtt gagagaacag cagca 295 <210> 95 <211> 1441 <212> DNA <213> Homo sapiens <400> 95 acaatagtcc agcttttatt agtcaaatca cccaagccgt ctctcaggct ctcggtattc 60 agtggaacct tcatacccct taccgtcttc aatcttcagg aaaggtagaa tggactaatg 120 atcttttaaa gacacacctc accaagctca gcctccaact taaagaggac tggacagtac 180 ttttacttct tgcccttctc agaattagcg cctgtccttg agatgctaca gggtacagcc 240 cttttgaact tttatatgga tgtgctttct tgcttggccc caaccttgtt ccagacacca 300 gccctctggg caactatctt ccagtcctcc agcaggctag acagaaaatt caccaggctg 360 ctaatcttct cacaaccttc cgtagcttct ctaataactt ctctgctagc atcgcagaca 420 tatcacaaac tttattaatc cttcaggccc aggttgactc tttagctgcg gttgtcctcc 480 aaaaccgcca aggccttgac ttactcactg ctaaaaaagg aggactctgt atatttttaa 540 atgaagagtg ttgtttttac ctaaatcaat ctggcctagt atatgacaac ataaaaaaac 600 tcaaggatag agcccaaaaa cttgccatcc aagtaaataa ttatgctgaa cccccttggg 660 cactctctaa ttggatgtcc tgggtcctcc caattcttag ccctttaata cctgtttttc 720 tccttctctt atttgtacct tgtgtcttct gtttagtttc tcaattcata caaaaccaca 780 cccaggccat caccaatcat tctatacaac aaatgctcct tccaacaacc ccacaatatc 840 accccttacc ccaaaatctt tcttcagttt aatctctccc actctaatta cccatgccac 900 cacaatcctg ctcaaagcag ccctgagaaa catcgcccat tatctctcca taccacagcc 960 aaaatttttt gctgccccaa cacttctcca ctattttgtt ttgtttttcc actattttgt 1020 tttgttttgt tttgttttgt caggcctctg agcccaggct aagccatcat atcccctgtg 1080 acctgcaggt atacatctag atggcctgaa gcaactgacg aaccacaaaa gaagtgaaaa 1140 taggcagttc ctgccttaac tgatgacttt ccaccattgt gatttgttcc tgccccgccc 1200 caaccaatca atcgaccttg tgacattcct cccctggaca atgagtctca tgatctcccc 1260 tctgagcacc ttgtgacccc tgcacctgcc tgcaagagaa aacccccttt aactgtaatt 1320 ttccactgcc tacccaaatc ctataaaact gccccacccc atctcccttt gctgactcct 1380 ttttcggact cagtctgcct cgcctgcacc caggtgatta aaaagcttta ttgctcacac 1440 a 1441 <210> 96 <211> 1939 <212> DNA <213> Homo sapiens <400> 96 tgggtcaggc gcaaagtaag cccaccccac tgggaactat gttaaaaaaa aatttcaaga 60 tttaagggag attacggtgt tactatgaca ccagaaaaac ttagaacttt gtgtgaaata 120 gactggctag cattagaggt gggttggcta tcagaagaaa gcctggagag gtcccttgtt 180 tcaaaggtat ggcacaaggt aacctgtaag ccaaagcacc cggaccagtt tctatacata 240 gacagttaca gctggtttta gacccccttc cccctctccc cacagtagtt aagagaacag 300 cagcataagc agctggcaga ggcaaggaaa gaccagcaga gagaaaaaaa ggccatctat 360 accaatttta agttaattta gactgaacaa ggtcttatta atagcaaagg ataattgaaa 420 tcacaaactt ataaggtttt caacaaaagt gaagtttgct aaaagttaac agtgtaacat 480 gtattatggt aacttctaat cttgtggcct tagacagtct agtcaaaaca cataaagaaa 540 gtttgcttta aaaaaacaat ggttatcttc aaaaataaag gggagaggca gaatttatat 600 aaaaagagtt atatgataaa ttcttgtcct gaaataaatt aactggttgt ttaaagaaaa 660 gaatgtttgt aataagtcaa aaagttaaaa catgtttaaa aaattgtctg caaaagtcat 720 aaaagaaaaa attttattaa aaaaatttta agcaaaaaat gttgtataat ttaaaagtaa 780 taaggcctcc tgtgtactat taagacagat gcaaattcct ggttgaaatg gatcaaatat 840 tccatctgca cattaaacaa aagcaattgt tatgcttgtg cacatggcag gccagaggcc 900 ctgattgtcc cccttccact aaggtggtcc tctagtcgac caggcgtgga ctgcatggta 960 gctcttttcc aggattctac agcctggagt aataagtcat gccaagctct ctctgctata 1020 tcccaaagtc tctgcgggtc agcccccaag ggccatgcag cttctgtctc ccaacactaa 1080 gttcacttcg tgtctctcac ggcagagagg aaacttagta ttccttggag acctgaaggg 1140 atgcagtgag cttaagaatt ttcaagagct tatcaatcag tcagcccttg ttcatccccg 1200 agtggatgtg tggtggtatt gtggtggacc tttactgggc actctgccaa ataactagtg 1260 tggcacttgt gctttagtcc atttggctat ccctttcacc ctggcatttc atcaaccaaa 1320 aaaaaaaaga aaaaagaaaa actcatgtcg gccccagccc tgaggctacc tgacctgaca 1380 aaactcttta cactctgtgt cagaaagaga aaaaatggca gttggagttt taacccagaa 1440 tgtagggccc tgaccaaggc cagtggccta tctctcaaaa caactagacg gggtttccaa 1500 aggctggccc ccatgtccaa gggtcctggc agcaagggcc ctgttagcac aagaagcaaa 1560 taagctaact cttagacaaa acctaaacat aaagtccccc catgctatgg tgattttaat 1620 aaataacaaa ggaaaccatt agctaatgaa tgctagacta actagatacc aaagcttgct 1680 ctgtgaaaat ccccgcataa ccactgaagt ttgcaacacc ctaaaccctg ccaccttgct 1740 ccccgtatca gagagcccag ttaaacataa ctgtgtagaa gtactggact cagtttattc 1800 tagtaggccc aaccactgag accacgctta aacatcagta gactaggagc tgtacgtgga 1860 taggagaagc ttcgccaacc cctgcaaagt gactctgaag aagatgacaa gccctgctcc 1920 agtcacaccc ggaagctga 1939 <210> 97 <211> 5815 <212> DNA <213> Homo sapiens <400> 97 gtcaggcctc tcagcccaag ctaagccatc atatcccctg tgacctgcat gtacacatcc 60 agatggccag ttcctgcctt aactgatgac attccaccac aaaagaaatg aaaatggcct 120 gttcctgcct taactgatgg cattatcttg tgaaattcct tctcctggct catcctggct 180 caaaagctcc cctactaagc accttgtgac ccccactcct gcctgccaga gaactacccc 240 cctttccttt acctacccaa atcctataga atggctccac cccgtctccc ttcgctgact 300 ctctttttgg actcagccca cctgcaccca ggtgaaataa acagccttgt tgctcacaca 360 aagcttgttt ggtggtcttt tcacatggat gtgagtgaaa tttggtgcca tgactcagat 420 cgggcaagct cccttaggag atcaatcccc tgtcctcctg ctctttgctc cgtgagagag 480 agccacctat gacttctggt cctcagacca agcagcccaa gcaagatctc accaatttta 540 aatctggtaa gcagcctctt tttactctct tctccaacct ccctcactat ccctcaacct 600 ctatctcctt tcaatcttgg tgccacactt caatctctcc cttctcttaa tttcaattcc 660 tttcattttc tggtagagac aaaggaggca cattttatcc gtggacccaa aactctggcg 720 ctggtcatgg actagggaag gcagccttcc cttggtgttt aatcattgca gggacacctc 780 tctgattatt cacccaggtt tcagaggtgt cagaccacgc agggacgcct gtcttggtcc 840 ttcaccctta gcggcaagtc ctgcttttct gggggagggg caagaaccct tcaacacctt 900 ctctttcacc cttagtggca agtcccgctt ttctggagga ggggcaggaa tcccgaccta 960 atatctctgc accccgatcc cttatttcca tgccccaacc tcttatctct gtgccccaac 1020 cccatatttc cacgccctga ccccttctct gcttttctgg agggcaagaa ccccccaccc 1080 cttctctgtg tctctactct cttttctctg ggcttgcctc cttcactatg cacaagcttc 1140 caccttccat tcctccttct tctcccttag cctgtgttct taagaactta aaacctcttc 1200 aattctcacc tgacctaaaa tctaagcatc ttattttctt ttgcaatgcc gcttgacccc 1260 aatacaaact cgacagtagt tccaaatagc cggaaaatgg cactttcaat ttttccatcc 1320 tacaagatct aaataattct tgtcaaaaaa tggccaaatg gtctgaggtg cctgacatcc 1380 aggcattctt ttatacatcg gtccctccct agtctctgtt cccaatgcaa ctcgtcccaa 1440 atcttccttc tttccctccc acctgtctcc tcagtcccaa ccccaagcat cactgagtct 1500 ttctaatctt ccttttctac agacccatct gacctctccc ctcctcccca ggctgctcct 1560 caccaggctg agctaggtcc caattcttcc tcagcctcca ctcctccacc ctataatcct 1620 tttatcacct cccctcctca caccaggtct ggcttacagt ttcattccct gactggccct 1680 ccccaacctg cccagcaatt tactcttaaa aagttggctg gagttaaagg catagtcaaa 1740 gttagtggtc ctttttcttt atcccaaatc agatagcatt taggctcttt ttcatcaaat 1800 ataaaaatcc agcccagttc atgactcgtt tggcagcaac cctgagatgc tttacagccc 1860 tagaccctaa aaggtcaaaa ggccgtctta ttctcaatat acattttatt acccaatctg 1920 ctcccgatat taaataaaac tccaaaaatt aaattccagc cctcaaaccc cacaacagga 1980 cttaattaac ctcgccttca aggtgtacaa taatagagta gaggcagcca agtagcaaca 2040 tatttctgag ttgcaattcc ttgcctccac tgtgagacaa accccagcca catctccagc 2100 acacaagaac ttccaaacac ctaaaccgca gtggccaggt gttcctccag aacctcctcc 2160 cccaggagct tgctacaagt gccagaaatc tggccaccaa gccaaggaat gcctgcagcc 2220 cgggattcct cctaagctgt gtcccatctg tgggggaccc cagtggaaat cagactgttc 2280 aactcacctg gcagccactc ccagagcccc tggaactctg gcccaaggct ctctgctgac 2340 tccttcccag atcttcttgg cttagcggct gaagactgac actgcccgat tgcctcggaa 2400 gccctgtaga ccatcacgga cgccgagctt taggtaactc tcacggtgga gggtaagtcc 2460 gtccccttct gaatcaatac ggaggctacc tactccacat tactttcttt tcaagggcct 2520 gtttcccttg cctccataac tgttgtgggt attgacagcc aggctgctaa acctcctaaa 2580 actccccaaa tctggtgtca acttagacaa tactctttta agcactcctt tttagttatc 2640 cccacctgcc cagtttcctt attaggctga gacactttaa ctaaattatc tgcttccctg 2700 actattcctg gagtacagct acatctcatt gccgcccttc ttcccaatcc aaagcctcct 2760 ttgcttcctc ctcttgcatc cccccacctt aacccacaag tataagatat ctctactccc 2820 tccttggtga ccaatcatgc accccttacc atctcattaa aacctaatca cccttgccct 2880 gcttaatgcc aatatcgcat cccacagcat gctttgaaag gattaaagcc tgttatcact 2940 cgcctgctac agcgtggcct tttaaagcct ataaactctc cttacaattc ccccatttta 3000 cctgtcctaa aaccagacaa gccttacaag ttagttcagg atctatgcct tatcaaccaa 3060 attgttttgc ctatccaccc catggtgcta aacccatata ctctcctata cttgataact 3120 ccctccacaa tccattattc tgttctggat ctgaaacatg ctttctttac tattcctttg 3180 cacccttcat cccagcctct ctttgctttc acctggactg accctgacac ccatcaagct 3240 cagcaaatta cctaggcttt actgctgcaa agcttcacag atagccccca ttacttcagt 3300 caagcccaaa tttcttcctc atctgttacc tatctcagca taattctcag aaaaacacat 3360 gcactctccc tgctgatcgt gtccagctaa tctcccaaac cccaatccct tctacaaaac 3420 aacaactcct ttccttcctg ggcatggttg gatactttca cgtttggata cctggttttg 3480 ccatcctaac aaaaccatta tataaactca caaaaggaaa cctagctgac cccatagatc 3540 ctaaatcctt tccccactcc tctttccatt ccttgaagac agctttagag gctgccccca 3600 tcctagctct ccctgactca tcccaaccct tttcattaca cacagccgaa gggcagggct 3660 gtgaagtcgg aattcttaca caaggaccgg gatcacgtcc tgtagccttt ttgtccaaat 3720 aacttgacct tactgtttta ggctggccat catgtctcca tgcagcggct gctgccgccc 3780 taatactttt agaggccctt aaaatcacaa aatatgctca actcactctc tacagctctc 3840 ataatttccg aaatctattt tcttcctcac acctgacacg tatactttct gctccctggc 3900 tccttcagct gtactcactc tttgttgagt ctcccacaat taccattgtt cctggctcgg 3960 acttcaatgt ggcctctcac attattcctg ataccacact tgaccctcat gactgcatct 4020 ctctgatcca cctgacgttc accccatttc cccacatttc cttcttccct gtttctcacc 4080 ctgatcacac ctggtttatt gatggcagtt ccaccaggcc taatcgccac atgccagcaa 4140 aggcaggcta tgatatagta caagccacta gcctgcctct tagaacctct catttccttt 4200 ccatcatgga aatctatcct caaggaaatc acttctcagt gttccatctg ctattctgct 4260 acttctcagg gattattcag gccccctccc ttccctacac atcaagctca gggatttgcc 4320 cccacccagg actggcaaat tagctttact caacatgccc cgagtcagga aactaaaata 4380 cctcttggtc taggtagaca ctttcactgg ataggtacag gcctttccca cagggtctaa 4440 gaaggccacc acggtcactt cttcccttct gtcagtcaaa attactcggt ttggccttcc 4500 cacctctagg cagtccaata gtagaccggc ctttattcat caaatcagcc aagcagtttt 4560 tcaggctctt ggtattcagt gaaaccttta tatcccttac agtcctcagt cttcaggaaa 4620 ggtagaatgg actaatggtc ttttaaaaac acacctcacc aagctcagtc accaacttaa 4680 aaaggactag acagtacttt tacctctttc ttttctcaga atttaggcct gtcctcagaa 4740 tgctacaggg tacagcccat ttgagctcct gtatggacgc tccattttat taagccccag 4800 tctcattcca gacatcagac caacttggac tgtgccccaa aaacttgtca tccctactat 4860 cttctgtcta gtcatactcc tattcaccgt tctcgactac tcatatatgc cctgctcttg 4920 tttacactgc cggtttacac cgtttctcca agccatcaca gctgatatct cctggtgcta 4980 tccccagact gccactctta actcttaaag taaataaata atctttgctg gcaaggctat 5040 gctgaacctc cttaggcact ctctaattag atgtcctaag tcctcccaat tcttagtcct 5100 ttaatacctg tttttctcct tctcttattc cctttagttt ttcaatacat acaaaaccgt 5160 atccaggcca tcaccaataa ttctaaatga caaatatttc ttctaacagt cccacaatgt 5220 caccccttac cacaaaatct tccctcagct taatctctcc cactctaggt tcccatgcta 5280 cccctaatcc cgctcaaagc agccctgaga aacatcgccc attatctctc catactatcc 5340 ccccaaattt tcgccatccc aacactttac cactatttcg ttttattttt ctcattaata 5400 taagaagaca ggaatgtcag gcctccgagc ccaagctaag ccatcatatc ccctgtgacc 5460 tgcacatcca catccagatg gccggttcct gccttaactg atgacattcc accacaaaag 5520 aaatgaaaat ggcctgttct tgccttaact gatggcatta tcttgtgaga ttccttctcc 5580 tggctcatcc tggctcaaaa gctcccctac tgagcacctt gtgaccccca ctcctgcctg 5640 ccagagaaca accccccttt ttcctttacc tacccaaacc ctataaaaca gccccacccc 5700 tatctccctt cactgactct cttttcggac acagccctgc acccaggtga aacaaacagc 5760 cttgttgctc acacaaagcc tgtttggtgg cctcttcaca gggacgcaag tgaaa 5815 <210> 98 <211> 67 <212> DNA <213> Homo sapiens <400> 98 atatggacag cccaccccaa gggaagaatc agaggagaag ggacacaaga ccccagaaac 60 acacaaa 67 <210> 99 <211> 5531 <212> DNA <213> Homo sapiens <400> 99 gtcaggtctc tgagcccaag ctaagccatc atatcccctg tgacctgcac gtacacatcc 60 agatggccgg ttcctgcctt aactgatgac attccaccac aaaagaaatg aaaatggcct 120 gttcctgcct taactgatga ctttatcttg tgaaattcct tctcctggct cattctggct 180 caaaagctcc cctactgagc accttgtgac ccccactcct gcctgccaga gaacaaccct 240 cctttttcct ttacctaccc aaatcctata aaacagcccc acccctatct cccttcgctg 300 actctctttt cggactcagc ccacctgctc ccaggtggaa taaacagctt tattgctcac 360 acaaagcctg tttcatggtc tcttcacacg aacacaagtg aaatttggtg ccgtgactca 420 gatcggggga cctcccttgg gtgatcaatc ccctgtcctt ctgctctttg ctctgtgaga 480 acgatccacc tatgacctca ggtcctcaga ctgaccagcc caagaaacat ctcaccaatt 540 tcaaatccgg taagcagcct ctttttactc tcttctccaa cctccctcac tatccctcaa 600 actctttctc ctttcaatct tggtgccaca cttcaatctc tcccttctct taatttcaat 660 tcctttcatt ttctggtaga gacaaaggag acacgtttta tctgtggacc caaaactctg 720 gtgccagtca cggactaggg aaggcagcct tcccttggtg tttaatcatt gcagggatgc 780 ctctctgatt attcacccag gtttcagagg tgtcaaacca cgcaaggatg cctgccttgg 840 tccttcaccc ttagcagcaa gtcctgcttt tctgggggag gggcaagaat cccaacccct 900 tctctccgtg tctctacccc ttctctgctt ttctggggga ggggcgagaa cccctcaacc 960 ccttctcctt cacccttagc ggcaagtccc gcttttctgg gggaggggca ggaaccctga 1020 cctcttatct ctgcaccctg atccctcatt tccgtgcccc aacctcttat ctctgcatcc 1080 caatctctta tctctgtgcc ccaacccctt atttctgccc ccccgacccc ttctctgctt 1140 ttctggaggg caagaacccc ccaccccttc tccatgtctc tactctcttt tctctgggct 1200 tgctccttca ctatgggcaa gcttccacct tccattcctc cttcttctcc cttagcctgt 1260 gttcttaaga acttaaaacc ttttcaactc tcacctgacc taaaatctaa gtgtcttatt 1320 ttcttctgca atgccgcttg accccaatac aaactcgaca gtagttccaa atagccagaa 1380 aatggcactt tcaatttttc catcctacaa gatctaaata attcttgtca taaaataggc 1440 aaacagtctg aggtgcctga catccaggca ttcttttaca cattgggccc tccctagtcc 1500 ctgttcccaa tgcaacttgt cccaaatctt ccttctttcc ctcccgcctg tcccctcagt 1560 cccaacccca agtgtccctg agtctttcta accttccttt tctacagacc tatctgacct 1620 ctcccctctt caccaggcta agctaagtcc caattcttcc tcagcctccg ctcctccacc 1680 ctataatcct tttatcacct ccccttctca caccctgtcc agcttacagt ttcgttctgt 1740 gactagccct ccccaacctg cccagcaatt tcctcttaaa aaggtggctg gatctaaagt 1800 catagtcaag gttaatgctc ctttttcttt atcccaaatc agatagtgtt taggctcttt 1860 ttcatcaaat ataaaaaccc agcccagttc atggcttgtt tggcagcaac cctgagatgc 1920 tttacagccc tagaccctaa aaggtcaaaa ggccgtctta ttctcaatat acattttatt 1980 tacccaatct gctcccgaca ttaaataaaa ctccaaaaat taaattccgg ccctcaaact 2040 ccacaacagg acttaattaa cctcgccttc aaggtgtata ataatagaga aaagttgcaa 2100 ttccttgcct ccactgtgag acaaacccca gccacatctc cagcacacaa gaacttccaa 2160 acgcctgaac tgcagtggcc aggcattcct ccagaacctc ctcccccagg agcttgctac 2220 gagtgccaaa aatctggcca ccaagccaag gaatgcccgc agcccaggat tcctcctaag 2280 ccatgtccca tctttgtgga accccactga aaatcggact gttcaactca cctggcagct 2340 actcccagag cccctggaac tctggcccaa ggctctctga ctgactcctt cccagatctt 2400 ctcagcttag tggctgaaga ctgacgctgc ccgatcacct aggaagcccc gtagaccatc 2460 acggacgcca agctttaggt aactctcaca gtggaggata agtccatccc cttcttaatc 2520 aatacggagg ctacctactc cacattacct tcttttcaag ggcctgtttc ccttgcctcc 2580 ataactgttg tgggtattga cgggcaagct tcaaaacccc tgaaaactcc ccaactctgg 2640 tgccaacttg gacaatactc ttttatgcac tcttttttag ctatccccac ctgcccagtt 2700 cccttattag gccgagacac tttaactaaa ttatctgctt ccctgactat tcctggatta 2760 cagctacatc tcattgctgc ccttcttccc aatccaaagc ctcctttgaa tcctcctctt 2820 gtatcccccc accttaaccc acaagtataa gatgcctcta ctccctcctt ggtgaccgat 2880 catgcacccc ttaccatctc attaaaacct aatcaccctt accccactca atgccaatat 2940 cccatcccac agcacgcttt aaaaagatta aagcctgtta ttactcgcct gctacagcat 3000 ggccttttaa agcctataaa ctctccttac cattccccca ttttacctgt cctaaaacca 3060 gacaagcctt acaagttagt tcaggatcta tgccttatca accaaattgt tttgcctatc 3120 caccccatgg tgccaaaccc atatactctc ctatcctcaa tacctccctc cacaatccat 3180 tattctgttc tagatctcaa acatgctttc tttactattc ctttgcaccc ttcatcccag 3240 cctctcttcg ctttcacttg gactgaccct gacacccatc aggctcagca aattacctag 3300 gctgtactgc cgcaaagctt cacagacagc ccccattact tcaatcaagc acagatttct 3360 tcctcatctg ttacctatct cagcataatt ctcataaaaa cacatgtgct ctccctgctg 3420 attgtgtccg gctaatctcc caaaccccaa tcccttctac aaaacaactc ctttccttcc 3480 taggcatggt tagtgcggtc agaattctta cacaagagcc aggactgcac cctgtagcct 3540 ttctgcccaa acaacttgac cttactgttt tagcctagcc ctcatgtctg tgtgcagcag 3600 ctgccactgc tttaatactt ttagaggccc taaaaatcac aaactatgct caactcactc 3660 tccacagttc tcataacttc caaaatctat tttcttcctc ccacctgacg catataattt 3720 ctgctcccag gctcctttag ctatactcac tcttcattga gtctcccaca attaccattg 3780 ttcctggccc agacttcaat ctggcctccc acattattcc tgataccaca cctgatcccc 3840 atgactgtat ctctctgctc cgcctgacat tcaccccatt tccccgcatt tccttctttc 3900 ctgttcctca ccctgatcac acttagttta ttgatggcag ttctgccagg cctaatcacc 3960 acacaccagc aaaggcaggc tatgctatag tacaagccac tagcccgcct cttagaacct 4020 ctcatttcct ttccatcgtg gaaatctatc ctcaaagaaa taacttctca gtgttccatc 4080 tgctatacta ctacttctcg gggattattc aggccccctc ccttccctac acatcaagct 4140 cggggatttg cccccaccca ggactggcaa attggcttta ctcaacatgc tccgagtcag 4200 aaaactaaaa tacctcttag tctaggtaga cactttcact ggataggtag aggcctttcc 4260 cacagggcct aaggaggcca ccacagtcat ttcttctctt ctatcagatg taattcctca 4320 gtttggcctt cccacctcta tacagtccaa tagcagaccg gcctttacta gtcaaatcac 4380 ccaagcagtt tctcaggctg ctagtattca gtgaactaat ggtcttttaa aaacacacct 4440 caccaagctc agccaccaac ttaaaaagga ctagacaatt tcccttctca gaattcaggc 4500 ctgtcctcag aatgctataa ggtacagccc atttgagctc ctgtatagac gctccttttt 4560 attaggcccc agtctcattc cagacaccag accaactcgg actgtgcccc aaaaaacttg 4620 tcatccctac tatcttctgc ctagtcatac tcctattcac tgttctcaac tactcataca 4680 tgccctgctc ttgtttccac tgccggttta cactgtttct ccaagccatc acagctgata 4740 tctcctggtg ctatccccaa actgccactc ttaactctta aacaaataat ctttgctggc 4800 aggactatgc tgaatctcct taggcactct aattagatgt cctgggtcct cccaattctt 4860 agacttttaa tacctgtttt tctccttctc ttattccatt tagtttttca attcatataa 4920 aactgtatcc aggccatcac caataattct aaatgacaaa tgtttcttct aacagtccca 4980 caatatcacc ccttaccaca aaatcttcct tcagcttaat ctctcccact ctacgttccc 5040 acgccacccc taatcccgct caaagcagcc ctgagaaaca ttgcccattc tctctccata 5100 ccacccccaa aaattttcac catctcaaca ctttaccact atttcatttt atttttctta 5160 ttaatataag aagacaggaa tgtcaggcct ctgagcccaa gctaagctat catatcccct 5220 gtgacctgca cgtacacatc cagatggccg gttcctgctt taactgatga tattatcttg 5280 tgaaattcct tctcctggct catcctggct caaaagctcc cctactgagc accttgtgac 5340 ccccactcct gcttgtcaga gaacaacccc cctttttcct ttacctaccc aaatcctata 5400 aaatggttcc acccctatct cccttcgctg actcttttcg gactcagccc acctgcaccc 5460 aggtgaaata aacagcttta ttgctcacac aaagcctgtt tggtggtctc ttcaaacaga 5520 cgcgagtgaa a 5531 <210> 100 <211> 990 <212> DNA <213> Homo sapiens <400> 100 aagaacacgt gagaaagtgt ggggaaaaga aagagaaatc agattgttac tgtgtctatg 60 tagaaaagga aacataagaa actccatttt gatctgtatt aagaaaaatt gtttctgctt 120 tgagatgctg ttaacttgta actttatccc caaccctgtg ctcacagaaa catgtgctgt 180 attggatcaa agtttaatgg atttaggact gtgcaggatg tgccttgtta atatgtttgc 240 aggcagtatg cttggtaaaa gtcatcgcca ttctccattc tctgttaacc aaggacacaa 300 tgcactgtgg aaagccacag ggacctctgc ccaagaaagc ctgggtattg tccaacgttt 360 cccccaactg agacagcctg agatatggcc tcatgggaaa ggaaagacct taccatcccc 420 cagcccgaca cccataaagg gtctgtgctg aggaggagga gtgaaagagg gaggcctctt 480 tgcagttgag ataagaggaa ggcttctctg ctcatccctg ggaatggaat gtctctgtgt 540 aaagccgacc attcccattc attctattct gagataggag aaaaccgccc tgtggctgga 600 ggcgagatat gctggcagca atactgctct gttgctcttt gctacactga gatacttggg 660 taaagagaaa cataaatcta gccttcgtgc acatccgggc acagtatctt tccttgaact 720 tactcatgat acagattcct ttgctcacat gtttccctgc tgaccttctc cccacctgtt 780 gccctgctac actccccttg ctaagatagt aaagatcatg atcaataaat actgagggaa 840 ctcagaggct ggcgccggtg cgggtccttc gtatgctgag cgccagtgcc ctgggcccac 900 tgttctttct ctgtactttg tccctgtgtc tatttctttt ctcagtctct catcccacct 960 gacgagaaat acccacaggt gtgaaggggc 990 <210> 101 <211> 5698 <212> DNA <213> Homo sapiens <400> 101 gttaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac atatatgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aaggccctgc cccgccttaa 120 ctgatgacat tccaccactg tgatttgttc ctgccccacc ttaactgagt gattaaccct 180 gtgaatttcc ttctcctggc tcagaagcta ccccactgag caccttgtga cccccgcccc 240 tgcccaccag agaacaacct cctttgactg taattttcca ttaccttccc aaatcctata 300 aaacggcccc acccctatct cccttcgctg actctctttt cggactcaac cgcctgcacc 360 caggtgaaat aaacagccat gctgctcaca caaagcctgt ttggtagtct cttcacacgg 420 acacacatga aatttggtgc catgactcgg atcgggggac ctcccttggg agatcaatcc 480 cctgtcctcc tgctctttgc tccatgagaa agatccacct acgacctcag gtcctcagac 540 tgaccagccc aagaaacatc tcaccaattt caaatccggt aagcggcctc tttttactat 600 cttctccagc ttccctcact atccctcaac ctctttctcc tttcaatctt ggcaccacac 660 ttcaatctct cccttctctt aatttcaatt cctttcattt tctggtagag acaaaggaga 720 cacgttttat ccatggaccc aaaactccgg tgccggtcac ggactgggac ggcagccttc 780 ccttgatgtt taatcattgc agggacacct ctctgattat tcacccacgt ttcaaaggtg 840 tcagaccacg cagggacacc tgccttggtc cttcaccctt agcggcaagt cccgcttttc 900 tggggaaggg gcaagtaccc caaccccttc tctccttgtc tctacccctt ctctgctttt 960 ctgggggagg ggcaagaacc cctcaacccc ttctccttca cccttagtgg caagtcccac 1020 ttttctgggg gaggggcaag tacccctcaa ccccttctcc ttcaccctta gcagcaagtc 1080 ccacttttct agggggcaag aacccccaat cccttatttc cgctccccaa cctcttatct 1140 ctgtgcccca attccttatt tccatgcccc aaccctttct ctgcttttct ggagggcaag 1200 gaacccctac cccttctctg tgtctctact cttttctctg ggcttgcctc cttcactatg 1260 ggcaagattc caccttacat tcctcctcct tctcccttag cctatattct taagaactta 1320 aaacctctcc aactttcact gacctaaaat ctaagcgtct tattttcttc tgcaatgccg 1380 cttgacccca atacaaactt gacagtagtt ccaaacaccg gaaaatggca ctttcaattt 1440 ttccatccta caagatctaa ataattcttg tcgtaaaagg ggcaaatggt ctgaggtgcc 1500 tgacgtccag gcattctttt acacatcagt cccttcctag tctctgtgcc cagtgcaact 1560 catcccaaat cttccttctt tccctcccgc ctgtcccctc agtcccaacc ccaagcgtcg 1620 ctgagtcttt ctaatcttcc ttttctatag acccatgtga cctctcccct cctcaccagg 1680 ccaagctagg tcccaattct tcctcagcct ctgctcctcc accctgtaat ctttttatcg 1740 cctcccctcc tcacacctgg tccggcttac agtttccttc tgtgactagc cctccccaac 1800 ctgcccagca atttactctt aaaaaggtga ctggagccaa aggcatagtc aaggttaatg 1860 ctcatttttc tttatcccaa atcagaagcg tttaggctct ttttcatcaa atataaaaac 1920 ccagcccagt tcatggcttg tgtggcagca accctgagat gctttacagc cctagaccct 1980 aaaaggtcaa aaggccatct tattctcaat atacatttta ttacccaatc tgctcccgac 2040 attaaataaa actccaaaaa ttagaatctg gccctcaaac cccacaacag gacttaacct 2100 taccttcaag gtgtacaata ataaaaaaaa agttgcaact ccttgcctcc actgtgagac 2160 aaaccccagc cacatctcca gcacacaaga acttccaaac gcctgaaccg cagcagccag 2220 gcgttcctcc agaacctcct cccccaggag cttgctacaa gtgccagaaa tctggccacc 2280 aggccaagga atgcctgcag cccaggattc ctcctaagcc gtgtcccatc tgtgcgggac 2340 cccatgggaa atcggactgt tcaactcacc tggcagccac tcccagagcc cctggaactc 2400 tggcccaagg ctctctgact gactccttct tggcttagcg gctgaagact gatgctgtct 2460 gattgcctcg gaagccccat agaccatcac ggatgctgag ctttaggtaa ctctcagagt 2520 ggagggtaag tccgtcccct tcttaatcaa tacgaaggct acccactcca cattaccttc 2580 ttttcaaggg cctgtttccc ttgcctccat aactgttgtg ggtattgaca gccaggcttc 2640 taaacctctt aaaactcccc aactctggtg ccaacttaga caatactctt ttaagcactc 2700 ttttttagtt atccccacct gcccagttcc cttattaggc cgagatattt taaccaaatt 2760 atctgcttcc ctgactattc ccggactata gccgcatctc attgctgccg ttcttcccaa 2820 tccaaagcct cctttgcgtc ctccttttgt attcccccac cttaacccac aagtataaga 2880 tacctctact ccctccttgg cgaccgatca cgcacccctt accatctcat taaaacctaa 2940 tcaccctcac cccactcaat gccaatatcc catcccacag catgctttaa aaggattaaa 3000 gcctgttatc actcgcctgc tacagcatgg gcttctaaaa cctataaact ctccttacca 3060 ttcccccatt ttacctgtcc taaaaccaga caaggcttaa aagttagttc agaatctgcg 3120 ccttatcaac caaattgttt tgcctatcca ccccgtggtg ccaaacccat atactctcct 3180 atcctcaaaa cctccgtcta caatccatta ttctgttctg gatctcaaac atgctttctt 3240 tactattcct ttgcaccctt catcccagcc tctctttgcc ttcacttaga ctgaccctga 3300 cacacattag gctcagcaaa ttacctgggc tgtactgccg caaggcttca cagacagccc 3360 ccgttacttc agtcaagccc aaatttcatc ctcatctgtt acctatcttg gcataattct 3420 cataaaaaca caggtgctct ccctgctgat catgtccaat taatctccaa aacctcaatc 3480 ccttacaaaa caacaactcc tttccttcct aggcatggtt agtgtggtca gaattcttac 3540 acaagagcca ggaccacacc gtgtagcctt tctgtccaaa caaattgacc ttactgtctt 3600 agcctagccc tcatgtctgc atgcagcggc tgccgctgct ttaatactgt tagaggccct 3660 aaaaaatcac aaactatgct caactcactc tctacatttc tcgtaacttc caaaatctat 3720 tttcttcctc atacctgacg catatacttt ctgctcccca gctccttcag ctgaactcac 3780 tctttaagtc ccacaactac cattgtttct ggcccggact tcaatctggc ctcccacatt 3840 attcctgata ccacacctga cccccatgac tgtatctctc tgatccacct gatattcacc 3900 ccatttcccc atatttcctt ctttcctgtc cctcaccctg aacacacttg gtttattgat 3960 ggcagttcca ccaggcctaa tcgccacaca ccagcaaagg caggctatgc tatagtacga 4020 gccactagcc cgcctctcag aacctctcat ttcctttcca tcgtggaaat ctatcctcaa 4080 ggaaataact tctcagtgtt ccatctgcta ttctactact cctcagggat tattcaggcc 4140 ccctcccttc cctacacatc aagctccagg atttgccccc acccaggacg ggcaaattag 4200 ctttactcaa catgtcccga gtcaggaaac taaaatagct cttagtctaa atagacgctt 4260 tcactgaata agtaatggcc tttcctacag ggtctgagaa ggccaccaca gtcatttctt 4320 cccttctgtc agacataatt cctcagttta gccttcccac ctctatacag tctgataaca 4380 gaccagcctt tattagtcaa atcagccaag cagtttttca ggctctcagt attcagtgaa 4440 acctttatat cccttatggt cctccgtctt caagaaaagt agaacggact aaaggtcttt 4500 taaaaacaca cctcaccaag ctcagccacc aacttaaaaa ggactggaca atacttttac 4560 cactttcgct tctcagaatt caggcctgtc ctcagaatgc tacaaggtac agcccattta 4620 agctcctgta tagacgctcc tttttattag gccccagtct cattggacac cagaccaact 4680 tagactgtgc cccaaaaaaa cttgtcatcc ctactatctt ttgtctagtc atactcctat 4740 tcaccattct caactactca tacatgccct gctcttgttt acactgctgg tttacactgt 4800 ttctccaagc catcacagct ggtatctcct ggtgctatcc ccaaactgcc actctaaact 4860 cttgaagtaa ataaataatc tttgctggca ggactatggt gaatctcctt aggcactctc 4920 taatcagatg tcctagctct cccaattctt agacttttta tacctgtttt tctccttctc 4980 ttattccatt tagtttttca attcatacaa aaccgtatcc aggccatcac caatcattct 5040 atatgacaaa tgtttcttct aacaacccca caatatcacc ccttaccaca agacctccct 5100 tcagcttaat ctctcccact ctaggttccc acactgcccc taatcctgtt gaagcagccc 5160 tgagaaacat cgcccattct ctctccatac cacccccaaa aattttcgcc gccccaacac 5220 ttcaacacta ttttgtttta tttttcttat taatataagg aagcaggaat gtcaggcctc 5280 tgagcccaag ccaagccgtc gcatcccctg tgagttgcag gtatacgccc agatggccta 5340 agtaactgaa gaatcacaaa agtgaaaagg ccctgccccg ccttaactga tgacattcca 5400 ccattgtgat ttgttcctgc cccaccttaa ctaagtgatt aaccgtgtga atttccttct 5460 cctggctcag aagctccccc actgagcacc ttgtgacccc gcccctgccc accagagaac 5520 aacccccttt gactgtaatt ttccattacc ttcccaaatc ctataaaacg gtcccacccc 5580 tatctccctt cgctgactct ctttttggac tcagcccacc tgcacccagg tgaaataaac 5640 agccatattg ctcacacaaa gcctgtttgg tggtctcttc acacggaccc gcatgaaa 5698 <210> 102 <211> 5868 <212> DNA <213> Homo sapiens <400> 102 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac atatacgccc 60 agatggcctg aagtaactga agaatcacaa aagtgaatat gccctgcccc accttaactg 120 atgacattct accacaaaag aagtgtaaat ggccactcct tgccttaagt gatgacatta 180 ccttgtgaaa gtccttttcc tggctcatcc tggctcaaaa agcaccccca ctgagcacct 240 tgcgaccccc actcctacct gacagagaac aaaccccctt tgactgtaat tttcctttac 300 ctacccaaat cctataaaac ggccccaccc ttatctccct ttgctgactc ttttcagact 360 cagcctgcct gcacccaggt gaaataaaca gccttgttgc tcacacaaag cctgtttggt 420 ggtctcttca cacagacgcg catgaaattt ggtgccgtga ctcggatcag gggacctccc 480 ttaggagatc aatcccctgt catgttcttt gctccgtgag aaagatccac ctacaacctc 540 aggtcctaag accgaccagc ccaagaaaca tctcaccaat ttcaaatccg gtaagcggcc 600 tctttttact ctcttctcca acctccctca ctatccctcg acctctttct cctttcaatc 660 ttggtgccac acttcaatct ctcccttctc ttaatttcaa ttcctttcat tttctgggag 720 agacaaagga gacacgtttt atccgtggac ccaaaactcc ggtgccagtc acagactggg 780 aaggcagcct tcccttgacc tttaatcatt gcagggatgc ctctctgatt attcacccac 840 gtttcaaagg tgttagacca cgcagggatg cctgccttgg tccttcaccc ttagcggcaa 900 gtcccgcttt tctggggaag gggcaagtac cccaacccct cctctccttg tctctacccc 960 ttctctgctt ttctggggga ggggcaagta cccctcaacc ccttctcctt cactcttagc 1020 agcaagtcct gcttttctag aggaggggca agtaccccaa cctcgtatct ctgtgcccca 1080 atcccttatt tccgtgcccc aacctcttat atctctgtgc cccaatccct tatttctgtg 1140 ccctaactta actctgcgcc ccaatccttt atttccgtgc cccgacccct tatttccgtg 1200 ccccacccct tatttccatg ccctgacccc ttatttctgc accccatccc ttatttccac 1260 gccctgacct cttatctctg cgccccaacc ccttttctgg aaggtaagaa ccccgaaccc 1320 cttccctccg tttctctgct ctctcttttc tctaggcttg cttccttcac tataggcaac 1380 cttccaccct ccattcctcc ttctactccc ttggcctgtg ttctcaaaaa cttaaaacct 1440 cttcaactca caccttacct aaaacctaaa tgtcttattt tcttctgcaa tgccacttga 1500 ccccaataca aactctacag tagttccaaa tagccagaaa atggcacttt gaatttttcc 1560 atcctacaag atctaaataa ttcttgttgt aaaataggca aatggtctga ggtgcctgac 1620 gtccaggcat tcttttacac atcagtccct tcctagtctg tgcccagtgc aactcgtccc 1680 aaatcttcct tctttccctc ccgcctgtcc cctcagtccc aacaccaagc gtcgctgagt 1740 ctttctaatc ttccttttct acagacccat ctgacctctc ccttcctccc caggctactc 1800 cctgccaggc cgagctaggt cccaattctt cctcagcctc tgctactcca ccctataatc 1860 tttttatcac ctcccctcct cacacctggt ctggcttaca gtttagttct gtgactagcc 1920 ctccccctcc tgcccagcaa tttactctta aaaaggtggc tggagctaaa gccatagtca 1980 aggttaatgc tcatttttct ttatcccaaa tcagatagcg tttaggctct ttttcatcaa 2040 atataaaaat ccagcccagt tcatgacttg tttggcaaca accctgagac actttacagc 2100 cctagaccct aaaaggtcaa aaggccgtct tattctcaaa atacatttta ttacccaatc 2160 tgctcctgac attaaatata actccaaaaa ttaaattctg gccctcaaac cccacaacag 2220 gatttaatta acctcgcctt caaggtgtac aataatagaa aaaagttgca attccttgcc 2280 tccactgtga gacaaacccc agccccatct ccagcacaca agaacttcca aacgcctgaa 2340 ccgcagtggc caggcgttcc tccagaacct cctcccacag gagcttgcta cacgtgccgg 2400 aaatctggcc actgggccaa ggaatgcccg cagcccggga ttcctcctaa gccccgtccc 2460 atctgtgtgg gaccccactg aaaatcggac tgttcaactc acctggcagc cactcccaga 2520 gcccctggaa ctctggccca aggctctctg actgactcct tcccagatct tctcggctta 2580 gcggctgaag actgacactg cccgatcgcc tcggaagccc cctagaccat cacggacgct 2640 gagcttcagg taactctaac agtggaaggt aagcccgtcc ccttcttaat caatacggag 2700 gctacccact ccacattacc ctcttttcaa gggcctgttt cccttgcctc cataactgtt 2760 gtgggtattg acggccaggc ttctaaacct cttaaaactc cccaactctg gtgccaactt 2820 agacaatact cttttaagca ctccttttta gttatcccca cctgcccagt tcccttatta 2880 ggctgagaca ctaactaaat tatctgcttc cctgactatt cctggactac agctgtatct 2940 cattgccacc cttcttccca atccaaagcc tcctttgcgt ccccctcttg tatcccccca 3000 ccttaaccca caagtataag atacctctac tcccttcttg gcaaccgatc atgcacccct 3060 taccatctca ttaaaaccta atcaccctta ccccactcaa cgccaatatc ccatcccgca 3120 gcatgcttta aaaagattaa agcctgttat cactcgcctg ctacagcatg gccttttaaa 3180 gcctataaac tctccttaaa attcccccat tttacctgtc ctgaaaccag acaagcctta 3240 caagttagtt caggatctgc atcttatcaa ccaaattgtt ttgcctttcc accccatggt 3300 gccaaaccca tatactctca tatcctcagt acctgcctct acaacccatt attctgttct 3360 agatctcaaa catgctttct ttactatccc tttgcaccct tcatcccagc ctttcttcgc 3420 tttcacttgg actgaccctg acacccatca agctcagcaa attacctagg ctgtactgcc 3480 acaaagcttc tcagacagcc cccattactt caatcaagcc caaatttctt cctcatctgt 3540 tacctatctc ggcataattc tcataaaaac acacgtgctc tccctgccaa tctgtctgac 3600 tgatctctca aacccaagca ccttctacaa aacaacaact cctttccttc ctaagcacgg 3660 ttagcgcagt cagaattctt acacaagagc caggaccaca tcctgtagcc cttctgtcca 3720 aacaacttga ccttactgtt ttagcctagc cctcatgtct gcgtgcagcg gctgctgctg 3780 ctttaatact tttagaggcc ctcaaaatca caaactatgc tcaactcact ctctacagtt 3840 ctcataactt ccaaaatcca ttttcttcct catacctgac gcatatactt tctgcttccc 3900 ggcgccttca gctgtactca ctctttgttg agtctcccac aattaccgtt gttcctggcc 3960 cagactccaa tccggcctct cgcattattc tggataccac acctgacccc catgactgta 4020 tctctctgat ccacctgaca ttcaccccat ttccccaaat ttccttcttt cctgttcctt 4080 accctgatca cgcttgattt attgatggca gttccaccag gcctaatcgc cacacaccag 4140 caaaggcagg ctatgctata gtacaagcca ctagcctgcc tcttagaacc tctcatttcc 4200 tttccatcgt ggaaatctat cctcaaggaa ataacttctc agtgttacat ctgctattct 4260 actactcctc agggattatt caggccccct cccttcccta cacatcaagc tcgaggattt 4320 gctcccaccc aagactggca aattagcttt actcaacatg ccccgagtca gataactaaa 4380 atacctctta gtctaggtag acactttcac tggataggta gagtcctttc ctacagggtc 4440 tgagaaggcc actgcagtca tttcttccct tctgtcagac ataattcctc agtttagcct 4500 tcccacctca atacagtctg acaacagaca agcctttatt agtcaaatca gccagcagtt 4560 tttcaggctc ttagtattca gtgaaacctt tatatccctt acggtcctcc atcttcaaga 4620 aaagtagaat agactaaagg tcttttaaaa acacacctca ccaagctcag ccaccaactt 4680 aaaaaggact ggacaatact tttaccactt tcctttctca gaattcaggc ctgtcctcgg 4740 aatgctacag ggtacagccc atttaagctc ccgtacagac gctccttatt aggccccagt 4800 ctcattcgag acaccagacc aacttagact gtgccccaga aaacctgtca tccctactat 4860 cttctgtcta ctcatactcc tattcaccgt tctcaactac tcatacatgc cctgctcttg 4920 tttacactgc cagtttacac tgtttttcca agccatcaca gctgatatct cctggtgctg 4980 tccccaaact gccactctta actcttgaag taaataaata atctttgctg gcaggactat 5040 gctgaatctc cttaggcgct ctctaatcag atatcctgag tcgtcccaat tcttagacct 5100 tttatacctg tttttctcct tctgttattc catttagttt ctcaattcat ccaaaaccgt 5160 atctaggcca tcaccaatca ttctacacga caaatgtttc ttctaacaac cccacaatat 5220 caccccttac cacaagacct cccttcagct taatctctcc cactctaggt tcccacgccg 5280 cccctaatcc cgcttgaagc agccctgaga aacatcgccc attctctctc catatcaccc 5340 cccaaaaatt tttgctgccc caacacttca acactatttt gttttatttt tcttattaat 5400 ataagaagtc aggaatgtca ggcctctgag cccaagccaa gccatcgcgt cccctgtgac 5460 ttgcacatat acgcccagat ggcctgaagt aactgaagaa tcacaaaaga agtgaatatg 5520 ccctgcccca ccttaactga tgacattcca ccacaaaaga agtgtaaatg gccggtcctt 5580 gccttaagtg atgacattac cttgtgaaag tccttttcct ggctcatcct ggctcaaaaa 5640 gcacccccac tgagcacctt gcgaccccca ctcctgcccg ccagagaaca aacccccttg 5700 gactgtaatt ttcctttacc tacccaaatc ctataaaatg gccccaccct tatctccctt 5760 tgctgattct cttttcggac tcagcccacc tgcacccagg tgaaataaac agccatgttg 5820 ctcacacaaa gcccgtttgg tggtctcttc acacggacgt gcatgaaa 5868 <210> 103 <211> 5785 <212> DNA <213> Homo sapiens <400> 103 gtcaggcctc tgagcccaag ccaagccatc acatcccctg tgacctgcac gtatatgccc 60 agatggcctg aagtaactaa agaatcacaa aagaagtgaa tatgccctgc cccaccttaa 120 ctgatgacat tccaccacaa aagaagtgta aatggccagt ccttgcctta actgatgaca 180 ttaccttgtg aaagtccttt tcctggctca tcctggctca aaaagcaccc ccactgagca 240 ccttgcgacc ccaactcctg cgcactgagc accttacgac ccccactcct acccgccaga 300 gaacaaaccc cctttgactg taattttcct ttacctaccc aaatcctata aaacggcccc 360 acctttatct ccctccgctg actctctttt cggactcagg cgcctgcacc caggtgaaat 420 aaacagccat gttgctcaca caaagcctgt tttgtggtct cttcacacgg acgcgcatga 480 aatttggtgc catgactcgg atcgggggac ctcccttggg agatcaatcc cctgtcctcc 540 tgctctttgc tccgtaagaa agatccacct acgacctcag gtcctcagac ctaccagccc 600 aggaaacatc tcaccaattt caaatccggt aagcggcctc tttttactct cctctccaac 660 ctccctcact atccctcaac ctctttctcc tttcaatctt agcgccacac ttcaatctct 720 cccttctctt aatttcaatt cctttcattt tctggtagag acaaaagaga catgttttat 780 ccgtgaaccc aaaactccgg cgccggtcac agactgggaa ggcagccttc ccttggtgtt 840 taatcattgc agggacgcct ctctgattat acactcatgt ttcaagggtg tcagaccacg 900 cagggacacc tgccttggtc cttcaccctt agcggcaagt cccgctttcc tggggcaggg 960 gcaagtaccc ctcaacccct tcttcttcac ccttagaggc aagtcctgct ttcctagggg 1020 gcaagaagcc cccaatcgct tatttccgca ccccaacctc ttatctctgt gccccaatcc 1080 cttatttccg taccctgacc tcttatctct gtgccccaat cccttatttc catgccccaa 1140 ccccttttct gcttttctgg agggcaagaa ccccccaccc cttctccgtg tctctactct 1200 tttctctggg cttgcctcct tcactatggg taagcttcca ccttccattc ctccttcttc 1260 tcccttagcc tgtgttctca aaaacttaaa acctcttcaa ctcacacctg acctaaaacc 1320 taaatgcctt attttcttct gcaatgccgc ttgaccccaa tacaaactcg acagtagttc 1380 caaatagcca gaaaatggca ctttgaattt ttccatcctg caaaatctaa ataattcttt 1440 tcgtaaaata ggcaaacggt ctgaggtgcc tgacatccag gcattctttt acacatcagt 1500 cccttcctag tctctgtgcc cagtgcaact cgtcccagat cctccttctt tccctcccgc 1560 ctgtcccctc agtcccaacc ccaagcatcg ctgagtcttc ccagtctttc ttttctacag 1620 acccatctga cctttcccct cctccccagg ctgctcgtcg ccaggctgag ctaagtccca 1680 atacttcctc agcctccact cctccaccct ataatccttc tatcacctcc cctcctcaca 1740 cccggtccgg cttacagttt agttccacaa ctagctcttc cccacctgcc cagcaattta 1800 ctcttaaaaa ggtggctaga gccaaaggca taatcaaggt taatgctcct ttttctttat 1860 cccaaatcag atagcgttta ggctcttttt catcaaatat aaaaacccag cccagttcat 1920 ggctcgttcg gcagcaaccc tgagacactt tacagcccta gaccctaaaa ggtcaaaagg 1980 ccatcttatt ctcaatatac attttattac ccaatctgct cccgacatta aataaaactc 2040 caaaaattaa attccagccc tcaaacccca caacaggatt taattaacct cgccttcaag 2100 gtgtaaaata atagaaaaaa gttgcaattc cttgcctcca ctgtgagaca aaccccagcc 2160 acaatctcca gcacacaaga acttccaaat gcctgaaccg cagtggccag gcgttcctcc 2220 agaacctcct cccacaggag cttgctacat gtgccggaaa tctggccact gggccaagga 2280 atgcccgcag cctaggattc ctcctaagcc atgtcccatc tgtgtgggac cccactgaaa 2340 atcggactgt tcaactcacc tggcagccac tcccagcttc cctggaactc tggcccaagc 2400 ctctctgact gactccttcc cagatcttct cggcttagca gctgaagact gacactgcct 2460 gatcgcctcg ggagccccct agaccatcac ggacgccgag cttcgggtaa ctctcacagt 2520 ggagggtaag cccgtcccct tcttaatcaa tacggaggct actcactcca cattaccctc 2580 ttttcaaggg cctgtttcct ttgccgccat aactgttgtg ggtattgacg gccaggcttc 2640 taaacctctt aaaactcccc aactctgggg ccaacttaga caatactctt ttaagcactc 2700 ctttttagtt atccccacct gcccagttcc cttattaggc tgagacactt taactaaatt 2760 atctgcttcc ctgactattc ctggactaca gctgtatctc attgccgccc ttcttcccaa 2820 tccaaagcct cctttgcgtc ctccaaagcc tcctttgcgt cctcctcttc tatcccccaa 2880 ccttaaccca caagtataag atacctctac tccctccttg gcgactgatc atgcacccct 2940 taccatctca ttaaaaccta atcactctta ccccactcaa caccaatatc ccatcccgca 3000 gcatgcttta aaaagattaa aggctgttat cactcgcctg ctacagcatg gccttttaaa 3060 gcctataaac tctccttaca attcccccat tttacctgtc ctaaaaccag acaagcctta 3120 caagttagtt caggatctgc gccttatcaa ccaaattgtt ttgcctatac accccatggt 3180 gccaaaccca tatactctcc tatcctcaat acctgcctct acaacccatt attctgttct 3240 ggatctcaaa catgctttct ttactattcc tttgcaccct tcatcccagc ctctctttgc 3300 tttcacttag actgaccctg acacccatta ggctcagcaa attacctggg ctgtactgcc 3360 acaaggcttc acagacagcc cccattactt cagtcaagcc caaatttcat cctcatctgt 3420 tacctatctc ggcataattc tcataaaaac acacgtgctt tccctgccga tcctgtccga 3480 ttaatctccc aaacctcaat cccttacaaa acaacaactc ctttccttcc taggcatggt 3540 tagtgtggtc agaattctta cacaagagcc aagaccgcac cctgtagcct ttctgtccaa 3600 acaacttgac cttactgttt tagcctagcc ctcatgtctg tgtgcagcag ctgccgctgc 3660 tttaatactt ttagaggccc taaaaatcgc aaactatgct caactcactc tctacatttc 3720 tcataacttc caaaatctat tttcttcctc atacctgacg catatacttt ctgctccccg 3780 gctacttcag ctgtacccac tctttgttga ggctcccaca attaccgttg ttcctggccc 3840 agacttcaat ccagcctccc acattattcc tgataccaca cctgaccccc atgactgtat 3900 ctctctgatc cacctgacat tcaccccatt tccccaaatt tccttctttc ctgttcctca 3960 ccctgatcac gcttgattta ttgatggcgg ttccaccagg cctaatcgcc acacaccagc 4020 aaaggcaggt tatgctatag tacaagccac tagcccgcct cttagaacct ctcacttcct 4080 ttccatcgtg gaaatctatc ctcaagcaaa taacttctca gtgttccatc tgctgttcta 4140 ctactcctca gggattattc aggacccctc ccttccctac acatcaagct ccaggatttg 4200 ccccacccag gactggcaaa ttagctttac tcaacatgcc ctgagtcaga taactaaaat 4260 acctcttagt ctaggtagat actttcactg gataggtaga ggcctttcct acagggtctg 4320 agaaggccac cgcagtcatt tcttccattc tgtcagacat aattcctcag tttagccttc 4380 ccacctcaat acagtctgat aacagacgag cctctattag tcaaatcagc caagcagttt 4440 ttcaggctct tagtattcag tgaaaccttt atatcccttt atggtcctcc atcttcaaga 4500 aaagtagaat ggactaaagg tcttttaaaa acacacctca ccaagctcag ccaccaactt 4560 aaaaaggact ggacaatact tttaccactt tcccttctca gaattcaggc ctgtcctcgg 4620 aatgctacag ggtacagccc atttaacgtc ctgtatagac gctccttttt attaggcccc 4680 agtctcattc cagacaccag accaacttag actgtgcctc aaaaaaaaaa aaaaacttgt 4740 catccctact attttctgtc tagtcatact cctattcacc gttctcaact actcatacat 4800 gccctgctct tgtttacact gccggtttac actgtttttc caagcgatca cagctgatat 4860 ctcctggtgc tagccccaaa ctgccactct taactcttga agtaaataaa taatctttgc 4920 tggcaggact atgccaaatc tccttaagca ctctctaatc agacctcctg agtcgtccca 4980 attcttagac cttttatacc tgtttttctc cttctgttat tccatttagt ttttcaattc 5040 atacaaaacc gtatccaggc catcaccaat cactctatat gacaaatgtt tcttctaaca 5100 tccccacaat atcacccctt accacaagac ctcccttcag cttaatctct cccactctag 5160 gttcccacgc cgcccctaat cccgcttgaa gcagccctga caaacatcat ccattctctc 5220 tccataccac cccccaaaaa ttttcgccgc cccaacactg caacactatt ttgttttatt 5280 tttcttatta agaaggcagg aatgtcaggc ctctgagccc aagccaagcc atcacatccc 5340 ctgtgacctg cacgtatatg cccagatggc ctgaagtaac taaagaatca caaaagaagt 5400 gaatatgccc tgccccacct taactgatga cattccacca caaaagaagt gtaaatggcc 5460 agtccttgcc ttaactgatg acattacctt gtgaaagtcc ttttcccggc tcatcctggc 5520 tcaaaagcac ccccactgag caccttgcga ccccaactcc tgcgcactga gcaccttacg 5580 acccccactc ctacccgcca gagaacaaac cccctttgac tgtaattttc ctttacctac 5640 ccaaatccta taaaacggcc ccacccttat ctccctccgc tgactctctt ttcggactca 5700 gcccgcctgc acccaggtga aataaacagc catgttgctc acacaaagcc tgtttggtgg 5760 tctcttcaca tggacgcgca tgaaa 5785 <210> 104 <211> 5612 <212> DNA <213> Homo sapiens <400> 104 ctgccttaaa tgatgacatt ccaccacaaa agaagtgaaa atggcctgtt cctgccttaa 60 ctgatgacat tgtcttgtga aattccttct cctggctcat cctggctgga aagctcccct 120 actgagtatc ttgtgacccc cactctggcc accagagaac aaccccgctt tgactgtaat 180 tttcctttat ttacccaaat cctataaaac gtccccaccc ttatctccct tggctgaccc 240 tcttttcgga ctcagcccag ctgcacccag gtgaaataaa cagctttatt gctcacacaa 300 agcctgtttg gtggtctctt ccatggatgc aagtgaaatt tggtgccatg actcggatca 360 gggtacctcc cttgggagat caatcccctg tcctcctgct ctttgctcca tgagaaaggt 420 ccacctatga cctcaggtcc tcagaccgac cagcccaaga aacatctcac caatttcaaa 480 tccagtaagc agcctatttt tactctcttc ttcaacctcc ctcactatcc ctcaacctcg 540 ttctcctttc aatcttggcg ccacacttca acctctccct tctcttaatt tcaattcctt 600 tcattttctg gtagagacaa aggagacatt ttatccgtgg acccaaaact ccagcgcctg 660 tcacagactg ggaaggcagc cttcccttgg tgtttaatca ttgcagggac acctctgatt 720 attcactcat gtttcagagg tgtcatacca tgcaaggatg cctgccttgg tccttcaccc 780 ttagcagcaa gtcctgcttt tcttggggag gggcaagtac cccaacccct tctctccgtg 840 tctctacccc ttctctgctt ttctgaagga gaggcaagaa cccctcaacc ccttctcttt 900 cacccttagc ggcaagtccc gcttttctaa aggaggggca agtaccccga cctcttatct 960 ctgtgccccc atcccttatt tccacacccc gacctcttat ctccgtgccc caacccctta 1020 tttctgtgcc ttgacccctt ttctgctttt ctggaaggta agaactccca aaccccttcc 1080 ctctgtgtct ctactctctc ttttttctag gcttgcctcc ttcactatag gcaaacttcc 1140 accctccatt cctcctcctt ctcccttagc ctgtgttctt aagaacttaa aacctattca 1200 gctctcacct gacctaaaat ctaagcgtct tattttcttc tgcaatgctg cttgacccca 1260 atacaaactc acagtagttc caaatagcca gaaaacggca ctttcaattt ttccatcctg 1320 caagatctaa agaattcttg tggtaaaata ggcaaacggt ctgaggtgcc tgacgtccag 1380 gcattctttt acacatcagt cccttcctag tctctgtgcc cagtgcaact catcccaaat 1440 cttccttctt tccctcccgc ctgtcccctc tgtcccaacc ccaagcgtcg ctgagtcttt 1500 ctaatcttcc ttttctacag acccatctga cctctcccct cctccccagg ctgctcctcg 1560 ccaggccaag ctaggtccca attcttcccc agcctccagt cctccaccct gtaatctttt 1620 tatcacctcc tctcctcaca cccggtccag tttacagttt aattccgtga gtagccctcc 1680 cctacctgcc cagcaatttc ctcttaaaaa ggtggctaaa gctaaaggca tagtcaaagt 1740 taatgctcct ttttctttat cagacctctc ccaaatcagt gagcatttag gctgtttcat 1800 caaatatgaa aaacccagcc cagttcatgg cttattcggc agcaaccctg agacgcttta 1860 cagccctaga ccctaaaagg tcaaaaggcc gtcttattct caatatacat tttattaccc 1920 aatctgctcc cgacattaaa taaaactcca aaaattaaat tctggccctc aaaccccaca 1980 acaggactta attaacctca ccttcaaggt gtacaataat agagtagagg cagccaagta 2040 gcaacgtatt tctaagttgc aattatttgc ctccacggtg agacaaaccc cagccacatc 2100 tccagcacaa caagaactcc aaatacctga accacagctg ccaggggttc ctccagaacc 2160 tcctccccca ggagcttgct acaagtgccg gaaatctagc cactaggcca aggaaggccc 2220 acagcccaag attcctccta agccatgtcc catctgtgca ggaccccact gaaaattaga 2280 ctgttcaact cacctggcag ccacttccag agcccctgga actgtggccc aaggctctct 2340 gactgactcc ttcccagatc ttctcagctt agcagctgaa gactgacact gcctgatcgc 2400 ctcagaagcc tacaggacca tcacagatgc tctaagtaac tctcacagta gaaggtaagt 2460 ccgtcccctt cttaatcaat acggaagcta ctcactccac attaccttat tttcaaaggc 2520 ctgtttccct tgcttccata actgttgtgc gtattgacag ccaggcttct aaacctctta 2580 aaactcccca aatctagtgc caacttagac aatactcttt taagcactcc tttttagtta 2640 tccccacctg cccagttccc ttattaggcc gagacacttt aactaaatta tctgcttccc 2700 tgactattcc taggctacag ccacacctca ttgctgcctt ttctcccagt tcaaagcctc 2760 cttcacatcc tccccttata tctccccacc ttaacccaca agtataagac acctctactc 2820 cctccttagt gaccgatcat gcacccctta ccatcccatt aaaacctaat cactcttacc 2880 ccgctcaatc ccaatatccc atcccacagc atgctttgaa aagattaaag cctgttatca 2940 cttacctgtt acagcatggc cttttaaagc ctataaactc ttcttgccat tcccccattt 3000 tacctgtcct aaaaccagac aaggcttaca ggttagttca gaatctgtgc cttatcaacc 3060 aaattgtttt gcctatccac cccatggtgc caaacccata tactctctta tcctcaatac 3120 ctccctctac aacccattat tctgttctag atctcaaaca tgctttcttt actattcctt 3180 tgcacccttc atcccagcct ctctttgctt tcacttaggc tgaccctgac acccattagg 3240 ctcagcaaat tacctgggct gtactgccac aaggcttcac agacagcccc cattacttca 3300 gtcaagccca aatttcatcc tcatctgtta cctatctcgg cataattctc ataaaaacac 3360 acgtgctctc cctgctgatt gtgccaatta atctcccaaa cctcaatccc ttataaaaca 3420 acaactcctt tccttcctag gcatggttag tgcggtcaga attcttacac aagagccagg 3480 accgcaccct gtagcctttc tgtccaaaca acttgacctt actgttttag cctagccatc 3540 atgtctccgt gcagcggctg ctgctgccct aatactttta gaggccctca aaatcacaaa 3600 ctatgctcaa ctcactctct acatttctca taacttccaa aatctatttt cttcctcata 3660 gctgatgcat atactttctg ctccccggat ccttcagctg tactcactct ttgttaagtc 3720 ccacaattat cattgttcct ggcccggact tcaatctggc ctcccacatt atacctgata 3780 ccacacctga cccccatgac tgtatccctc tgatccacct gacattcacc ccatttcccc 3840 atatttcctt ctttcctgtg cctcaccctg atcacactta gtttattgat ggcagttcca 3900 ccaggcctaa tcaccacaca ccagcaaagg caggctatgc tatagtacaa gccactagcc 3960 cgcctcttag aacctctgat ttcctttcca tcgtggaaat ctatcctcaa agaaataact 4020 tctcagtgct ccatctgcta ttctactact tctcaaggat tattcaggcc ccctcccttc 4080 cctacacatc aaactcaagg gtttgcccct gcccaggact agcaaattga ctttactcaa 4140 catgccctga gtcaggaaac taaaatacct cttggtctag gtacacactt tcactagata 4200 ggtagaggcc tttcccacaa ggtgtaagaa ggccaccacg gtcatttctt ccctgctgtc 4260 agacataatt cctcagtttg gccttcccac ttctacacag tccgatagaa gactggcctt 4320 tgttagtcaa atcagccaag cattttttca ggctcttaat atccagtgaa acctttatat 4380 cccttacagt cctcagtctt caggaaaagt agaacggact aatagtcttt taaaacacac 4440 ctcaccaagc tcagccacca acttaaaaag gactagataa tacttttacc actttccctt 4500 ctcagaattc aggcctgtcc tcagaatgct acaaggtaca tcccatttaa gctcctgtat 4560 agacgctcat ttttattagg ccccagtctc attccagaca ccagaccaac ttggactgtg 4620 ccccaaaaaa cttgtcatcc ctactatctt ctgtctagtc attcctattc actgttctca 4680 actactcata catgccctgc tcttgtttac actgccagtt tacactgttt ctccaagcca 4740 tcacagctga tatctcctag tgctatcccc aaactgccac tctaaactct tgaagtaaat 4800 aaataatctt tgctggcagg actatgctga atctccttaa gcactctcta atcagatgtc 4860 ctaggtcctc ccaattctta gaccttttat acctgttttt ctccttctct tattccattt 4920 agtttttcaa ttcatacaaa accatatcca ggccatcacc aataattcta caggacaaat 4980 gtttcttcta acaaccccac aatatcaccc cttaccacaa aatcttcctt cagctgaatc 5040 tctcccactc taggttcccg cgccgcccct aatcccgctc gaagcagccc tgagaaacat 5100 cgcccattat ctctccatac cacccccaaa aattttcacc atctcaacac tttaccacta 5160 tttcatttta tttgtcttat taatataaga agacaggaat gtcaggcctc tgagcccaag 5220 ctaagccatc atatcccctg tgaccttcat gtacacatcc agatggctgg ttcctgcctt 5280 aactgatgac attctaccac aaaagaagtg aaaatggcct gttcctgcct taactgatga 5340 cattgtcttg tgaaattcct tctcctggct catcctggct caaaagctcc cctactgagc 5400 accttgtgac ccccactctg cccaccagag aacaaccccc ctttgactgt aattttcctt 5460 tatctaccca aatcctataa aacggcccca cccttatttc ccttcactga ctctcttttc 5520 agactcaggc cacctgcacc caggtgaaat aaacagcttt attgctcaca caaagcctgt 5580 ttggtggtct cttcacaggg acatgaatga aa 5612 <210> 105 <211> 5687 <212> DNA <213> Homo sapiens <400> 105 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcat gtacacatcc 60 agatggcctg ttcctgcctt aactgatgac attccaccac aaaagaaatg aaaatggcct 120 gttcctgcct taactgatga cattatcttg tgaaattctt tctcctggct catcctggct 180 caaaagctcc cctgagcacc ttgtgacccc cactcctgcc tgccagagaa cccccctttt 240 tcctttacct acacaaatcc tataaaacgg ccccacacct atctccctta gctgactctc 300 ttttcaggct cagcccgcct gcacccaggt aaaataaaca gccttgttgc tcacacaaag 360 cctgtttggt ggtctcttca cacggacgca catgaaattt ggtgccgtga ctcggattgg 420 gggacctccc ttgggagatc aatcccccgt ctttgctccc tgagaaagat ccacctacaa 480 cctcaggtcc tcagacccac cagcccaagg aacatcacac caattttaat tcaggtaagc 540 agcctctttt tactctcttc tccaacctcc ctcactatcc ctcaacctcc ttctcctttc 600 aatcttggtg ccacacttca atctctccct tctcttaatt tcaattcctt tcattttctg 660 gtagagacaa aggagacacg ttttatcagt ggacccaaaa ctccggtgcc ggtcatggac 720 tagggaaggc agccttccct tggtgtttaa tccttgcagg gacacctctc tgattattca 780 cccaggtttc agaccacgca gggatgcctg ccttggtcct tcacccttag cggcaagtcc 840 cgcttttctg ggggaggggc agggaccgcg acctcttatc tctgcacccg gatcccttat 900 ttccatgctc caacctctta tctctgtgcc ccaacccctt atttccatgc ccttctctgc 960 ttttctggag ggcaagaacc ccccacccct tctccgtgtc tctactctct tttctctggg 1020 cttgcctcct tcactatagg caaccttcca ccttccgttc ctccttcttc tcccttagcc 1080 tgtgttctta agaacttaaa acctcaactc tcacctgacc taaaatctat gcgtcttatt 1140 ttcttctgca atgctgcttg accccaatac gaactcgaca gtagttctaa atagccagaa 1200 aatggcactt tcaatttttc catcctacaa gatctaaata attcttgtca taaaataggc 1260 aaatggtctg aggtgcctga catccaggca ttcttttaca catcagtcct tccctagtct 1320 ctgttccgaa tgcaactttt ccgaaatctt ccttctttcc ctcctgcctg tccactcagt 1380 tccaacccca accgtcactg agtctttcta atcttccttt tctacagacc catctgacct 1440 ctcccctcct cgctaggctg agctaggtcc caattattcc tcagcctccg ctcctccacc 1500 ctataatcct tttatcacct cccctcctca cacccagtcc ggcttacagt ttcattcctc 1560 gactagccct cccccacctg cccagcgatt tactcttaaa aaggtggctg gagctaaagg 1620 catagtcaaa gttaatgctc ctttttcttc atcccagatc agatagcgtt taggctcttt 1680 ttcatcaaat ataaaaaccc agcccagttc atggcttgtt tggcagcaac cctgagatgc 1740 tttacagccc tagaccctaa aaggtcaaaa ggccgtctat tctcaatata cattttatta 1800 cccaatccac tcctgacatt aaataaaact ccaaaaatta aattccagcc ctcaaacccc 1860 acaacaggac ttaattaacc tcaccttcaa ggtgtacaat aatagagtac aggcagccaa 1920 gtagcaatgt atttctgagt tgcaattcct tgcctccact gtgagacaaa ccccagccac 1980 atctccagca cacaagaact ccaaatgccc gaaccgcagc tgccaggggt tcctccagaa 2040 cctcctcccc caggagcttg ctacatgtgc cggaaatctg gccactggtc caaggaatgc 2100 ccacagcctg ggattcctcc taagccacgt cccgtcggtg cgggacccca ctgaaaatcg 2160 gactgttcaa ctcacctggc agccactctc agagcccctg gaactctggc ccgaggctct 2220 ctgactgact ccttcccaga tcttctcagc ttagtggctg aagactgacg ctgcctgatt 2280 gcctcagaag ccccctagac catcatggac gccgagcttc gggtaactct catagtggag 2340 ggtaagtcca tccactcctt aatcaatacg gaggctaccc actccacatt accttctttt 2400 caagggcctg tttcccttgc ctccataact gttgtaggta ttgacggcca ggcttctaaa 2460 cctcttaaaa ctccccaact ctggtgccaa cttagtcaat actcttttaa gcactccttt 2520 ttaattatcc ccacctgccc agttccctta ttaggctgag acactttaac taaatcatct 2580 gcttccctga ctattcctgg gctacagcca caccttattg ctgccttttc ccccagttca 2640 aagcctcctt cacatcctcc ccttgtatct ccccacctaa gacacctcta ctccctcctt 2700 agcgaccgat catgcacccc ttaccatctc attaaaacct aatcaccctt acccctctca 2760 atgccaatat cccatcccac agcacgcttt aaaaggatta aagcctgtta tcactcgcct 2820 gctacagcat ggccttttaa ggcctataaa ctctccttac aattccccct ttttacttgt 2880 cctagaacca gacaagcctt acaggttagt tcaggatctg cgccctatca accaaattgt 2940 tttgcctatc caccctgtgg tgccaaatcc atatactctc ctatcctcaa tacctccctc 3000 cataacccat tattctgttc tggatctcaa acgtgctttc tttactattc ctttgcaccc 3060 ttcatcccag cctctctgct ttcacttgga ctgaccctga cacccatcag gctcagcaaa 3120 taacctgggc tgtactgcac caagtcttca cagacagccc ccattacttc agtcaagccc 3180 aaatttcttc ctcatctgtt acctatctca gcataattct tcataaaaac acatgtgctc 3240 tccctgccga tagtgtccga ctgatctctc aaaccccaac cccttctaca aaacaacaac 3300 tcctttcctt cctaggcatg cttggatact ttcgcctttg gatacctggt tttgccatcc 3360 taacaaaacc attatataaa ctcacaaaag gaaacctagc tgaccccata gatcctaaat 3420 cctttcccca ctcctctttc cattccttga agacagcttt agagactgcc cccaccccag 3480 ctctccctga ctcatcccaa cccttttcat tacacacagc tgaagtgcag ggctgtgcag 3540 tcggaattct cacacaagga ccaggatcat gtcctgtagc ctttttgtcc aaacaacttg 3600 accttactgt tttaggctgg ccatcatgcc tccgtgcagt ggctgctgct gccctaatac 3660 ttttagaggc ccttaaaatc acaaactatg ctcaactcac tctctacagc tctcataatt 3720 tccaaaatct attttcttcc tcacacctga cgcatatact ttctgctccc tgctccttca 3780 gctgtactta ctatttgttg agtctcccac aattaccatt gttcctggcc tggacttcaa 3840 tccggcctcc cacattattc caggtaccac acctgaccct catgactgca tctctctgat 3900 caaactgaca ttcaccccat gtccccatat ttcctttttt cctgttcctc accctgatca 3960 cacttagttt attgatggaa gttccatcag gcctaatcac cacacaccat caaaggcagg 4020 ctatgctata gtacaagcca ctagcctgcc tcttaaaacc tctcatttcc tttccatcat 4080 ggaaatctat cctcaaggaa ataacttctc agtgttccat ctgctattct actgcttctc 4140 agggattatt cggtccccct cccttcccta cacatcaaac tcgaggattt gcccccaccc 4200 aggactggca aattagcttt actcaacatg ccccgagtca gataactaaa atacctctta 4260 gtctaagtag acactttcac tggataggta gaggcctttc ctacagggtc tgaggaggct 4320 accgcagtca tttcttccct tctgtcagac ataattcctc agtttagcct ttccacatct 4380 ataccgtctg ataacagacc agcctttatt agtctaatca gccaagcagt ttttcagtct 4440 cttagtattc agtgaaacct ttatatccct tacggtcctc agtctgcagg aaaggtagaa 4500 cagattaatg gtcttttaaa aacacacctc accaagctca gccaccaact taaaaaggac 4560 tggacaatac ttttaccact ttcgcttctc agaattcagg cctgtcctca gaatgctaca 4620 gggtacagcc catatgagct cctgtataga cactcctttt tattaggccc cagtcttatt 4680 ccagacacca gaccaacttg gactgtgtcc caaaaaactt gtcatcccta ctatcttctg 4740 tctagtgata ctcctattca ccgttctcaa ctactcatac atgccctgct cttgtttaca 4800 ctgccagttt acagtttctc caagccatca cagctgatat ctcctggtgc tatccccaaa 4860 ctgccgctct taactcttga agtaaataaa taatctttgc tggcaggact acgctgaacc 4920 tccttaggca ctctctaata agatgtcctg ggtcctccca attcttagac atttaattcc 4980 tgtttttctc cttctcttat tccgtttagt ttttcaattc atacaaaacc atatccaggc 5040 catcaccaat aattctacac aacaaatgtt tcttctaaca accccacaat atcacccctt 5100 accacaaaat cttccttcag cttaatctct cccactctag gttcccatgc cgcccctaat 5160 cccgctggaa gcagccctga gaaacatcgc ccattatctc tccataccat cccccaaaat 5220 tttctctgtc ccaacacttt accactattt cattttattt ttcttattaa tataagaaga 5280 caggaatgtc aggcctctga ggccgagtta agccatcata tcccctgtga cctgcatgta 5340 cacatcctga tggcctgttc ctgccttaac tgatgacatt ccaccgcaaa agaaatgaaa 5400 atggccgttc ctgccttaac tgatgacatt atcttgtgaa attccttctc ctggctcatc 5460 ctggctcaaa agctccccta ctgagcacct tatgaccccc actcctgcct gccagagaac 5520 aaccccgctt tttcctttac ctacccaaat cctataaaac ggccccaccc ctgtctccct 5580 tagctgactc ttttcagact cagcccgcct gcacccaggt gaaattaata gccttgttgc 5640 tcacacaaag cctgtttggt ggtctcttca cagggacgtg catgaaa 5687 <210> 106 <211> 6143 <212> DNA <213> Homo sapiens <400> 106 gtcaggcctc tgagcccaag ctaagccatc atatcctctg tgacctgcat gtatacatcc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aatggcctgt tcctgcctta 120 actgatgaca ttaccttgtg aaattccttc tcctggctca tcctggctca aaagctcccc 180 tgctgagcac cttgtgaccc ccactcctgc cagccagaga acaaccccct ttgactgtaa 240 ttttccttta cctacccaaa tcctataaaa cagccccacc cctatctccc ttcactgact 300 ctcttttcag actcagccca cctgcaccca ggtaaaataa atggccttgt tgctcacaca 360 aagcctgttt ggtggtctct tcacacggac acaagtgaaa tttggtgccc tgactcggat 420 cgggggacct cccttgggag ctcaatcccc tgtcctcctg ctgtttgctc tgtgagaaag 480 atccatctac aaccttgggt cctcagacca accagcccaa ggaacatctc accaatttta 540 aatcgggtaa gcggcctctt tttactctct tctctaacct ctctgactat ccctcaacct 600 ctttctcctt tcaatcttgg cgccatcttt caatctctgc cttctcttaa tttcagttcc 660 tttccttttc tggtagagac aggagacgca ttttatccat gaacccaaaa ctccggcacc 720 actcatggac tcaggacgac agtcttccct tggtgtttaa tcacgcgggg atgcctgcct 780 gattattcac ccacgtttca gaggtgtctg accacatggg gatgcctgcc ttggtccttc 840 acccttagcg gcaagcacca cttttctggg gggcaagcac cccccgaccc cttctctcca 900 tgtctctacc ctctcttttc tgccttggtc cttcaccctt agtggcaagc accacttttc 960 tggagggcaa gcacccccct actccttctc tccatgtctc tacccctttt ccactttcct 1020 ggggggcaag caccccccac cccttctttc catgtctcta gcctctcttt tctctgggct 1080 tgcctccttc actatggaca accttccacc ctccattcct ccctcttctc ccttagcctg 1140 tgttctcaaa aacttaaaac ctcttcaact cacacctgat ctaaaaccta aatgccttat 1200 tttcttctgc aacactactt ggccccaata caaacttgac aatggctcta aatggccaga 1260 aaatggcact ttcaattttt ccatcctaca agatctagat aattcttgtc ataaaatggg 1320 caaacggtct gaggtgcctg acgtccaggc attcttttac acattggtcc ctccctagtc 1380 tctgttccca atgcaactca tcacaaatct tccttctttc cctccgcctg tcccctcagt 1440 cccaatccca agtgttgctg agtctttcca atcttccttt tttttttttt ttttttacag 1500 acccatctga cctctcccct cctccccagg ctgctccttg ccaggccgcg ccaggttcca 1560 attcttcctc agcctccgct cctccaccct ataatccttt tatcaactcc cctcctcaca 1620 cctggtcccg cttacagttt cattccatga ctagccctcc ccaacctgcc cagcaatttc 1680 ctcttaaaaa ggtggctgga gctgaaggca tagtcaaggt taatgctcct ttttctttac 1740 ccgacctctc ccaaatcagt tagcgtttag gctctttttc atcaaatatg aaaaacccag 1800 cccagttctt ggccccttta gcagcaaccc ttagactctt tacagcccta gactcggaag 1860 ggtcagaagt ccatctcatt ctaaatatgc attttatcac ccagccagct cctgacatta 1920 aataaaactc caaaaattaa ataaattcca gccctcaaac cccacaacag gacttaatta 1980 acctcacttt caaggtgtac aataatacag tagaggcagc caagtagcaa tgtatttctg 2040 agttgcaatt ccttacctcc actgtgagac aaaccccagc cacatctcta gcacacagga 2100 gctccaaacg cctgaaccgc agcttccagg ggttcctcca gaacctcctc ccccaggagc 2160 ttgcttcaag tgccagaaat ctggtcactg ggccaaggaa tgcccgcagc ctgggattcc 2220 tcctaagctg tgtcccatct gtacgggacc ccactggata tcagactctc caacttgccc 2280 agcagccact cccagagccc ctggaactct ggcccaaggc tctctgactg actccttccc 2340 agatctgctt ggcttagcgg ctgaagactg acgcagcccc gtcacctcgg aagccccctg 2400 gaccatcacg gacgccgagc tttgggtaac tcttacagtg gaaggtaagt ccatcccctt 2460 cttaatcaat acagaggcta cacactccac attacctttt caagggcctg tttcccttgt 2520 ctccataact gttgtgggta ttgacaacca ggcttctaaa cctcttaaaa ctccccaact 2580 ctggtgccaa cttggataac attctttaat gcactgcttt ttagttaatc ccacctgccc 2640 agctccctta ttaggtctag gcattttaac taaattatct gcttccctga ctattcctgg 2700 gctacagcca cacctcattg ccaccttttc ccccagttca aagcttcctt cacatcctcc 2760 ccttgtatct ccccacctta ccccacaagt ataggacacc tctactccct ccttggcgac 2820 caatcatgca ccacttacca tcccattaaa acctaatcac ccttacccca ctcaatgcca 2880 atatcccatc ccacagccca ctttaaaagg attaaagcct gttatcactc gcctgctaca 2940 gcatgggctt ctgaaacctg tatactctcc atacaattcc cctattttac atgtccaaaa 3000 accggacaag tcttacaagt tagttcagga tctgcgcctt atcaatcaaa ttgttttgcc 3060 tatccacccc gtggtgccaa acccatgtac tctcctatcc tcaatacctc cctccacaac 3120 ccattattct gttatggatc tcaaacatgc tttctttact attcctttgc acccttcatc 3180 ccagcctctc tttgctttca cttggactga ccctgacacc cattaggctc agcaaattac 3240 ctgggctgta ctgccacaag gcttcacaga taggctcagt caagcccaaa tttcttcctc 3300 atctgttaca tatcttggca taattctcat aaaaacacac gtgctctccc tgctgatcat 3360 gtccgactaa tctcccaaac cccaatccct tctacaaaac aacaactcct ttccttccta 3420 ggcatggtta gtgcagtcag aattcttaca caagagccag gactgtgccc tgtagccttt 3480 ttatccaaac aacttgacct tactgtttta gcctagtcct catgtctgtg tgcagcagct 3540 gccactgcct taatactttt agaggacctc aaaatcacaa actatgctca actcactctc 3600 taaaattctc ataacttcca aaatctattt tcttcctccc acatgatgca tatactttct 3660 tctccccagc tccttcagct atacttactc attgttgaat ctcccacagt tccattgttc 3720 ctggcccaga cttcaatccg gcctcccaca ttattcctga taccacacct gacccccatg 3780 actgtatctc tctgatccac ctgacattca ctccatttcc ccatatttcc ttctttcctg 3840 ttcactattg gtttattgat aaaccctgaa cactattggt ttattgatgg cagctccacc 3900 aggcctaatc gccacttacc agcaaaggca ggctatgctg tagtatcttc catacctatc 3960 attgaggcta cctctctgcc cccctccact acctctcaaa aagccaaact cattgcctta 4020 actcaagccc tcgctcttac aaaaggacta tgcatcaata tttatactga ctctaaatat 4080 gccttccata tcctgcacca ccatgctgtt atatgggcag aaagaaattt cctcactatg 4140 caagggtcct ctatcattaa tgcctcttta ataaaaactc ttctcaaagc tgctttactt 4200 ccaaaggaag ctggagtcac tcactgcaag ggccatcaaa agtcatcaga ttccatcact 4260 caggacaatg cttatgctga taaggtagct aaaaaagcag ctagcgttcc aacttctatc 4320 cctcacggca gtttttctcc ttctcatctg gccactccca cctactctcc cactgaaact 4380 tccacctatc gatctcttcc tacacaaggc aaatggttct tggaccaagg aaaatatctc 4440 cttccagcct cacaggccca ttctattctg tcatcatttc ataacctctt ccatggaggt 4500 tacaagctgc tagcccacct cttagaacct ctcatttcct ttcaatcatg gaaatctaac 4560 cttaaggaaa tcacttctca gtgttccatc tgctattcta ctactcctca gggattgttc 4620 aggccccccc acttccctac acatcaagct cggggatttg tccccaccca ggactggcaa 4680 attgacttta ctcacatgcc tcagtcagga aactaaaata cctcttggtc tgggtagaca 4740 ctttcactgg gtgggtagag gcttttccca cagggtctga gaaggccact gcagtcattt 4800 cttcccttct gtcagacata attcctcagt tggccttccc acctctatac agtctgataa 4860 cagaccagcc tttattagtc aaatcactca agcagtttct caggctgttg gtattcagtg 4920 aaacctttat atcccttacc atcctcagtc ttcaggaaag gtagaacaga ctaatggtct 4980 tttaaaaaca cacctcatca agctcagcca ccaacttaaa aagtaccgga caatactttt 5040 accacttgcc cttatcagaa ttcaggcctg tcctcagaat gctacagggt acagcccatt 5100 tgagctcctg tatagacgct cctttttatt aggccccagt ctcattccag acaccagacc 5160 aacttagact gtgccccgaa aaacttgtca tccctactat cttctgtctg gtcacactcc 5220 tattcactgt tctcaactac tcatacaagc cctgctcttg tttatgctgc cggtttacac 5280 tgtttctcca agccatcaca tctgatatct cctggtgcta tctccaaact gccactctta 5340 actcgctctt aaagtaaata aataatcttt gctggcaggg ctatgctgaa cctccttggg 5400 cactctctaa ttggatgtcc tgggtcctcc caattcttag tcctttaata cctgtttttc 5460 tcctcttatt ctgtttagtt tttcaattca tacaaaaccg tatccaggcc atcaccaata 5520 attctatatg acaaatgttt cttctaacaa ccccacaata tcacccctta ccacaaaatc 5580 ttccttcagc ttaatctctc ccactgtagg tccccacgct gccccaatcc cactcaaagc 5640 agccctgaga aacatcgccc attatctctc cagatcaccc cccaaaattt tcaccacccc 5700 aacacttcaa cactattttg ttttattttt cttattaata taagaagaca ggaatgtcag 5760 gcctctgagc ccaggctaag ccatcatatc ctctgtgacc tgcatgtata catccagatg 5820 gcctgaagta actgaagaat cacaaaagaa gtgaaaatgg tctgctcctg ccttaactga 5880 tgacattacc ttgtgaaatt ccttctcctg gctcatcctg gctcaaaagc tcccccgctg 5940 agcaccttgt gacccccccc cacccctgcc agccagagaa caaccccctt tgactgtaat 6000 cttcctttac ctacccaaat cctataaaac agccccgccc ctatctccct tcgctctctt 6060 ctgattcagc ccacctgcac ccaggtgaaa taaacagcct tgttgctcac acaaagcctg 6120 tttagtggtc tcttcacacg gac 6143 <210> 107 <211> 4410 <212> DNA <213> Homo sapiens <400> 107 cttctccctt agcctgtgtt cttaagaact taaaacctct tcaactctca cctgacctaa 60 aatctaagcg tcttattttc ttctgcaatg ccccttgacc ccagtacaaa ctcgacagta 120 gttctaaata gccagaaaac agcactttca atttttccat cctacaagat ctaaataatt 180 cttgtcgtaa aatgggcaaa tggtctgagg tgcctgacgt ccaggcattc ttttacacat 240 tggtctctcc ctagtctctg tgcccagtgg gactcgtccc aaatcttcct tctttccctc 300 ccgcctgtcc cctcagtcct aaccccaagc gtcgctgagt ctttctaatc ttccttttct 360 acagacccac ctgacctctc ccctcctccc caggctgctc ctcgccaggc cgagctaggt 420 tccaattctt cctcagcctg tctccaccct ataatctttt tatcacctcc cctcctcaca 480 cctggtccgg cttacagttt cgttccgtga ctagccctcc cctacctgcc cagcaattta 540 ctcttaaaaa ggtggctgga gctaaaggca tagtcaaggt taatgctcct ttttctttat 600 cccaaatcag aagcgtttag gctctttttc atcaaatata aaaatccagc ccagttcatg 660 actcgtttgg cagcaaccct gagacacttt acagccctag accctaaaag gtcaaaaggc 720 cgtcttattc ttaaaataca ttttattatc caatctgctc ctgacattaa atgaaactcc 780 aaaaattaaa ttctggccct caaaccccac aacaggattt aattaacctc accttcaagg 840 ttacaataat agaaaaaagt tgcaatttct tgcctccact atgagacaaa ccccagccac 900 atctccagca cataagaact tccaaacgcc tgaaccgcag tggccaggca ttcctccaga 960 acctcctccc ccaggagctt gctgcaagtg ccagaaatct gaccactggg ccaaggaatg 1020 cccgcagccc aggattcctc ctaagccgtg acccatctgt gtgggacccc actgaaaatt 1080 ggactgttca actcacctgg cagccacttc tagagcccct ggaactccgg cccaaggctc 1140 tctgactgac tccttcccag atcgtcttgg cttagcggct gaagactgac gctgcccaat 1200 cgcctcagaa gccccctaga ccatcacgga cgccgagctt tgggtaactc tcacagtgga 1260 gggtaagtct gtccccgtct taatcaatac cgaggctact cactccacat taccttattt 1320 taaacggcct gtttcccttg cctccataac tgctgtgggt attgacggcc aggcttctaa 1380 acctcttaaa actccccaac tccggtgcta acttagacaa tactctttta agcactcctt 1440 tttagttatc cccacctgcc cagttccctt attaggctga gacactttaa ctaaattatc 1500 tgcttccctg actattcctg gattacagct gcatctcatt gctgcccttc ttcccaatcc 1560 aaagcctcct ttgcgtcctc ctcttgtatt cccccacctt aacccacaag tataaaatac 1620 ctctactccc tccttggcga tcgatcatgc accccttacc atctcattaa aacctaatca 1680 cctttacccc actcaatgcc aatatcccat cccacagcat gctttgaaag gatgaaagcc 1740 tgttatcact cgcctgctat agcatggcct tctaaaacct ataaactccc tttacgatgt 1800 ccccatttca cctgttctaa aaccagacaa ggcttacagg ttagttcaac atctgcgcct 1860 tagcaaccaa attgttttgc ctatccaccc tgtggtgcca aacccatata ctctcctatc 1920 ctcaataact ccctccacaa tccattattc tgttctagat ctcaaacatg ctttttttac 1980 tattcctttg cacccttcat cccagcctct ctctgctttc acttggactg accctgacac 2040 ccatcaggct cagcaaatta cctgggctgt actgctgcaa gtcttcacag acagccccca 2100 ttacttcagt caagcccaaa tttcttcctt atctgttacc tatctcggca taattctcat 2160 aaaaacacat gtgctctccc tgctgattgt gtccgattaa tctcccaaac ctcaatccct 2220 tacaaaacaa caactccttt ccttcctagg catggttagt gtggtcagaa ttcttacaca 2280 agaggcagga ctgcaccctg tagcctttct gtccaaacaa cttgacctta ctgttttagc 2340 ctagccatca tgtctccgtg cagtggctgc tgccgctcta atacttttag aggccctcaa 2400 aatcacaaac tatgctcaat tcactctcca catttctcat aacttccaaa atctattttc 2460 tttctcatac ctgatgcata tgctttctgc tccccggctc cttcagctgt actcactctt 2520 tgttaagtcc cacaattacc gttgttcctg gcccatactt caatccggcc tcccacatta 2580 ttcctgatac cacacctgac ctccatgact gtatatctct gatccacctg acattcaccc 2640 catttcccca tatttccttc tttcctgttc ctcaccctga tcacgcttga tttattgatg 2700 gcagttccac caggcctaat tgccacacac cagcaaaggc aggctatgcc aggcacaagc 2760 cactagccca cctcttagaa cctctcattt tctttccatc gtggaaatct atcctcaagg 2820 aaataacttc tcagtgttcc atctgctatt ctactactcc tcagggatta ttcaggccct 2880 ctcccttccc tacacttcaa gctcgaggat ttgcccccac ccaggactgg caaataagct 2940 ttactcaaca tgccctgagt cagataacta aaatacctct tagtctaggt agacactttc 3000 actggatagg tacaggcctt tcctacaggg tctgagaagg ccaccgcagt catttcttcc 3060 cttctgtcag gcataattcc tcagtttagc cttcccacct ctatacagtc tgatagcaga 3120 ccagccttta ttagtcaaat cagccaagca gtttttcagg ctcttagtat tcagtgaaac 3180 ctttatatcc cttacggtcc tccgtcttca agaaaagtag aacggactaa aggtctttta 3240 aaaacacacc tcaccaagct cagccaccaa cttaaaaagg actggacaat acttaccact 3300 ttcacttctc agaattcagg tctgtcctcg gaatgctaca aggtacagcc catttgagct 3360 ccttttaatt aggccccagt ctcattccag acatcagacc aacttggact gtgccccaga 3420 aaacttgtca tccctactat cttctgtcta gtcatactcc tattcaccat tctcaactac 3480 tcatacatgc cctgctcttg tttacactga cagtttacac tgtttctcca agccagcaca 3540 gctgatatct cctggtgcta tccccaaact gccactctta actcttgaag taaataaata 3600 atctttgttg gcaggactat gctgaatctc cttaggcact ctctaatcag atgtcctgag 3660 ttgtcccaat tcttagacct tttatacctg tttttctcct tctcttattc catttagttt 3720 ttcaattcat acaaaattgt atccaggcca tcaccaataa ttctaaatga caaatgtttc 3780 ttctaacaac cccacaatat caccccttac cacaaaatct tccttcagct taatctctcc 3840 cactctaggt tcccacgccg ccccaatccc gctaaaagca gccctgagaa acatcgccca 3900 ttatctctcc atagcacccc caaaaaattt ttcaccatcc caacacttta ccactatttc 3960 attttatttt tcttattaat ataagaagac aggaatgtca ggcctctgag cccaagctaa 4020 gccatcatat cccctgtgac ctgcacgtac acatccagat ggccggttcc tgccttaact 4080 gatgacattc caccacaaaa agaagtgaaa atggcctgtt tctgccttaa ctgatgacat 4140 tgtcttgtga aattccttct cctggctcat cctggctcaa aagctccccc actgagtacc 4200 ttgtgacccc cactcctgcc cgccagagaa caacccccct ttgactgtaa ttttcctata 4260 cctacccaaa tcctataaaa tggccccacc cctatctccc cttgctgact ctcttttcgg 4320 actcagcccg cctgcaccca ggtgaaataa acagccatgt tgctgacaaa aagcctgttt 4380 ggtggtctct tcacacggac gcgagtgaaa 4410 <210> 108 <211> 563 <212> DNA <213> Homo sapiens <400> 108 ttagagtagg cagttaggca gaactgagca gggcaggaga gggcccctat caggtcgtca 60 ggcaaccatc aggtgatggt caggcagttg ttaaactgtg tcgctaaaat gataattggt 120 tgcagctggt tccagggacc tgcagtctcc cagtagatag aaaatacctg gagctagtga 180 tcagcagctt cctgataaga tctcaggagc taggcgagtc ggttcaaaca tgtgcactaa 240 gaggcaaaat gggagtttaa ctggtatatg accttcctct gggaatgctt gactggtaag 300 agaaaaatgc ctcaaacgag catacacaca acttcagtaa acgcactgca catgcggccc 360 ctcccaagtg ctggcaggtc actgtgcatg cagacagcct gccccaaggg gaaaattaag 420 ggaagaaaaa cacaaacccc ggaaccatgc caatgtataa aaccccaagc ccaaggctga 480 acagggcact tggatctctt atgttgccca cttgaccctc ttccaagtgt actttgcttc 540 ctttcattcc tgctctaaaa ctt 563 <210> 109 <211> 7137 <212> DNA <213> Homo sapiens <400> 109 gtcaggcctc tgagcccaag ccaagccatt gcatcccctg tgactgcaca tatatgccca 60 gatggcctga agtaactgaa gaatcacaaa agaagtgaat atgccctgcc ccaccttaac 120 tgatgacatt ccaccacaaa agaagtgtaa atggccggtc cttgccttaa gtgatgacat 180 taccttgtaa aagtcctttt cctggctcat cctggctcaa aaagcacccc cactgagtac 240 cttgcgaccc ccactcctgc ccgccagaga acaaaccccc tttgactgta attttccttt 300 acctacccaa atcctaaaaa acggccccac ccttatctcc cttcgctgac tctcttttcg 360 gactcagccc acctgcaccc aggtgaaata aagagcttta ttgctcacac aaagcctgtt 420 tggtggtctc ttcacatgga tgcgcatgaa atttggtgcc gtgactcgga tagggggacc 480 tcccttggga gataaatccc ccatcctcct gctctctgct ccatgagaaa gatccatcta 540 tgacctcagg tcctcagacc gaccagccca agaaacatct catcaatttc aaatccggta 600 agcgacctct ttttactctc ttctcctacc tccctcacta tccctcaagc tctttctcct 660 ttcaatcttg caccacactt caatctctcc cttctcttaa tttcaattcc tttcattttc 720 tgatagtgac aaaggagaca cgttttatcc atggacccgg aactctggcg ccggtcacgg 780 actgggaagg cagccttccc ttggtgttta atcattgcag ggacgcctct ctgattatac 840 acccatgttt caagggtgtc agaccacaca gggatgcctg ccttggtcct tcacccttag 900 cggcaagtcc cgcttttctg gggaaggggc aagtacccca accccttctc tccttgtctc 960 taccccttct ctgcttttcc agggacaggg cgagtacccc aaccccttct ctccttgtct 1020 ctaccccttc tctgcttttc caggaacagg gtgagtaccc caaccccttc tctccttgtc 1080 tctacccctt ctctgctttt ctgggagagg ggcaagtaac catcaacccc ttctccttca 1140 cccttagcag caagtcctgc ttttctgggg gaggggcaag taccccaacc tcatatctct 1200 gtgccccaat cccttatttc tgcaccccaa cctcttatat ctctgtgccc caatccctta 1260 tttctgcgcc ccaacctcgt atctctgcac tccaatccct tatttccatg ccccaacctc 1320 gtatctctgt gccccaatcc cttatttcca tgccccaacc tcttatctct gcaccccaac 1380 cccttttctg gaaggtaaga acccccaaac cccttccctc catttctcta ctctctcttt 1440 tctctaggct tgcttccttc actatgggaa acttccaccc tccattcctc agtctactcc 1500 cttggcctgt gttctcaaaa acttaaaacc tcttcaactc acacctgacc taaaacctaa 1560 atgccttatt ttcttctgca atgctgcttg accccaatac aaactcgaca gtagttccaa 1620 atagccagaa aatggcactt tgaatttttc catcctgcaa gatctaaata attcttgtcg 1680 taaaataggc aaacggtctg aggtgcctga tgtccaggca ttcttttaca catcagtccc 1740 ttcctagtct ctgtgcccag tgcaactcgt cccaaatctt ccttctttcc ctcccgcctc 1800 tcccctcagt accaacccca agcgtcgctg agtctttcta atcttccttt tctacagacc 1860 catctgacct ctgccttcct ccccaggctt ctcctctcca ggccgagcta ggtcccaatt 1920 cttcctcagc ctctgctcct ccaccctata atctttttat cacctcccct cctcacacct 1980 tgccggctta cagtttcgtt ccctgactag ccctccccaa cctgcccagc aattgactct 2040 taaaaaggtg gctggagcca aaggcatagt caaggttaat gctccttttt ctttatccca 2100 aatcagaagc atttaggctc ttttttatca aatataaaaa cccagcccag ttcatggctc 2160 gttcggcagc aaccctgaga cactttacag ccctagaccc taaaaggtca aaaggccatc 2220 ttattctcaa tatacacttt attacccgat ctgctcccga cattaaataa aactccaaaa 2280 attggaatct ggccctcaaa ccccacaaca ggatttaatt aacctcacct tcaaggtgta 2340 caataacaga aaaaagttgc aattccttgc ctccactgtg agacaaaccc cagccacgtc 2400 tccagcacac aagaacttcc aaacgcctga accgcagcag ccaggccttc ctccagaacc 2460 tcctccctca ggagcttgct acacgtgccg gaaatctggc cactgggcca aggaatgccc 2520 acagcccggg attcctccta agccgcgtcc catctgtgtg ggaccccagt gaaaatcgga 2580 ctgttcaact cacctgacag ccactcccag agctcctgga actctggccc agggctctct 2640 gactgactcc ttcccagatc ttctcggctt agcggctgaa gactgacact gcccgatcac 2700 ctcggaagcc ccctagacca tcacagactc cgagtttccg gtaactctca cagtggaagg 2760 taagcccgtc cccttcttaa tcaatacgga ggctacccac tccacattac cttcttttca 2820 agggcctgtt tcccttgcct ctataactgt tgtgggtatt gacggccagc cttctaaacc 2880 tcttaaaact ccccaactct ggtgccaact tagacaatac tcttttaagc actccttttt 2940 agttatcccc acctgcccag ttcccttatt aggctgagac actttaacta aatcatctgc 3000 tttcctgact attcctggac tacagctata tctcattgct gcccttcttc ccaatccaaa 3060 gcctcctttg catcctcctc ttgtatcccc caaccttaac ccacaagtat aagatacctc 3120 tactccctcc ttggcgaccg atcatgcacc ccttaccatc tcattaaaac ctaatcaccc 3180 ttaccccact cagtgccaat atcccatccc gcagcacgct ttaaaaagat taaagcctgt 3240 tatcacttgc ctgctacagc atggcctttt aaagcctata aactctcctt acaattcccc 3300 cattttacct gtcctaaaac cagacaagcc ttacaagtta gttcaggatc tgcgccttat 3360 caaccaaatt gttttgccta tccaccccgt gctgccaaac ccatatactc tcctatcctc 3420 aatacctgcc tctataaccc attattctgt tctagatctc aaacatgctt tctttactat 3480 tcctttgcac ccttaatccc agcctctctt cactttcagt tggactgacc ctgacaccca 3540 tcaagctcag caaattacct aggctgtact gctgcaaagc ttcacagaca gcccccatta 3600 cttcaatcaa gcccaaattt cttcctcatc tgttacctat cttggcataa ttctcataaa 3660 aacacacgtg ctctccctgt caatcatgtc cgactgatct ctcaaacccc agcaccttct 3720 acaaaacaac aactcctttc cttcctaggc atggttagtg cggtcagaat tcttacacaa 3780 gagccaggac cacaccctgt agcctttctg tccaaacaac ttgaccttac tgttttagcc 3840 tagccctcat gtctgcgtgc agcggctgcc actgcattaa tacctttaga ggccctcaaa 3900 atcacaaact atgctcaact cactctctac agttctcata acttccaaaa tctattttct 3960 tcctcatacc tgacgcatat actttctgct tcctggctcc ttcagctata ctcactcttc 4020 gttgagtctc ccacaattac cgttgttcct ggcccagact tcaatccggc ctcccacatt 4080 attcctgata ccacacctga cccccatgac tgtatctctc tgatccacct gacattcacc 4140 ccatttcccc aaatttcctt ctttcctgtt cctcaccctg atcacgcttg atttattgat 4200 ggcggttcca ccaggcctaa tcaccacaca ccaacaaagg caggttatgc tgtagtacaa 4260 gccactagcc cgcctcttag aacctctcat ttcctttcca tcatggaaat ctatcctcaa 4320 ggaaataact tctcagtgtt ccatctgcta ttctactact cctcagggat tattcaggcc 4380 ccctcccttc cctacacatc aagctccagg atttgcccca cccaggactg gcaaattagc 4440 tttactcaac atgccctgag tcagataact aaaatacctc ttagtctagg tagatacttt 4500 cactggatag gtagaggcct ttcctacagg gtctgagaag gccaccacag tcatttcttc 4560 ccttctgtca gacataattc ctcagtttag ccttcccacc tcaatacagt ctgataacag 4620 acgagccttt attagtcaaa tcagccaagc agtttttcag gctcttagta ttcagggaaa 4680 cctttatatc ccttacggtc ctccatcttc aagaaaagta gaatggacta aaggtctctt 4740 aaaaacacac ctcaccaagc tcagccacca acttaaaagg actggacaat acttttacca 4800 ctttcccttc tcagaattca ggcctgtcct cggaatgcta cagggtacag cccatttaag 4860 ctcctgtata gacgctcctt tttattaggc cccagtctca ttccagacac cagaccaact 4920 tagactgtgt ccccaaaaaa acttgtcatc cctactatct tctgtctagt catactccta 4980 ttcaccgttc tcaactactc atacatgccc tgctcttgtt tacactgccg gtttacactg 5040 tttttccaaa acatcacagc tgatatctcc tggtgctatc cccagactgc cgctcttaac 5100 tcttgaagta aataaataat ctttgctggc aggactatgc tgaatctgct taagcactct 5160 ctaatcagat atcctgagtc gtcccaattc ttagacattt tatacctgtt tttctccttt 5220 tgttattcca tttagttttt caattcatac aaaactgtat ccaggccatc accaatcatt 5280 ctatatgaca aatgattctt ctaacatccc cacaatatca ccccttacca caagacctcc 5340 cttcagctta atctctccca ctctaggttc ccacactgcc cctaatcccg cttgaagcag 5400 ccctgagaaa catcgcccat tctctctcca taccaccccc caaaaatttt cgccgcccca 5460 acacttcaac actgttttgt tttatttttc ttattaatat aagaaggcag gaatgtcagg 5520 cctctgagcc caagccaagc catcgcatcc cctgtgactt gcacgtatat gcccagatgg 5580 cctgaagtaa ctgaagaatc acaaaagaag tgaatatgcc ctgccccacc ttaactgatg 5640 acattccacc acaaaagaag tgtaaatggc cagtccgtgc cttaagtgat gacattacct 5700 tgtgaaagtc cttttcctgg ctcatcctgg ctcaaaaagc acccccactg agcaccttgc 5760 gacccccact cctgcccgcc agagaacaaa ccccctttga ctgtaatttt cctttaccta 5820 cccaaatcct ataaaacggc cccaccctta tctcccttcg ctgactctct tttcggactc 5880 agcccgcctg caccaaggtg aaataaacag ccatgttgct caaacaaagc ctgtttggtg 5940 gtctcttcac atggacgtgc atgaaagtca ccacataggg gaaaggtgga aagtggaagt 6000 gagctcatga gacgagagag aaaatctggc tgaactcatc tttttttatt aggaactcac 6060 tcccacagta attaactgac tcccaagata aagacattta tccattcccc tcatggccta 6120 atcatccctt aaaagcatca cttcttaata ttgttacaat agcaattcag cttccaacac 6180 atgaattcta gggaacatat tcacaatata gtagaaccag tcacgtgaca accatcaata 6240 actggaaaga agcaagatag aatggtcttc ttattagttt gggaaacaaa tgagaactag 6300 gtatgagtaa gcactagggc tttctacagt tctccagtgg tctgtaagtc aacatatttt 6360 aaattgttat tatgtgtcaa cattgaagcc cacatacaaa aataaatcaa tgtaatacac 6420 tatattacat aaacagataa aacacataat gatttcagta gattcagaga aagaatttga 6480 cagaattcaa catagtttta tatgattaaa agcactggat gaaacagaaa cagaaggcct 6540 atgtaagcca atttaaattt tattggatat catccctaat gatgaatgaa acataacatt 6600 tcatatcaca cagttgcgta ataatagagg taaaaaagta ctggcaggac aaaaagattt 6660 taatcaagag attttgagag atgcttcagt gatgaaatga aacaaattta aaaagagaac 6720 aactttggta tataattaga agtcagaaat ctaaatatca gatttaatac tgtcaggcct 6780 ctgagcccaa gcctgcaggt atacatccag atggccctaa gcaagtgaag aatcacaaaa 6840 gaagtgaaaa tggccagttc ctgccttaac tgatgacatt atcttgtgaa attccttctc 6900 ctggctcaga agctcccccg ctgagcacct tgtaaccccc acccctgcca gcaagagaac 6960 aaaccccttt gactgtaatt ttccactacc cacccaaatc ctataaaacg gccccacccc 7020 tatctccctt cgctgactct cttttcggac tcagcctgcc tgcagccagg tgattaaaaa 7080 gctttattgc tcacagaaag cctgtttcgt ggtcttttca cacggacgcg catgaaa 7137 <210> 110 <211> 478 <212> DNA <213> Homo sapiens <400> 110 ttacagtagt cagatagtca ggcatgagca gggcaggaga gggctccgcc tcaccacgaa 60 catcaggcaa ccatcaggta agggtcaggt ggttgttacc cgtctctcta aaataataat 120 tgatcacagc tggcaccagc agaaggcaat ctccctatag atagaaaaaa aactgaaact 180 ggtgatcagc agctttctga taacatctcg ggaattgggg gagtgagctc aaacatgtga 240 agtgagaggc agaaagttgg agtttaactg gtaaatgacc tttctaggag cattcggctg 300 gtaagggaag aatgcctcaa gtgagcatgt gtataacttc agtaaacaca ctgcacatgc 360 tcagcttgca agtactggca ggccactgca catgcagaca cccaacccca agagaagaat 420 caagggagaa gggacgcaag accgcagaag tatgccaaca tataaaacat ataagtca 478 <210> 111 <211> 377 <212> DNA <213> Homo sapiens <400> 111 gtcaggtctc tgagcccaag cctgcacgta ttcattcaga tggcctgaag caagtgaaga 60 atcacaaaag aactgaaaat ggccggttcc tgccttaact ggtgacatta ccttgtgaaa 120 ttccttctcc tggctcgtcc tggctcagga gctccccgac tgagcacctt gtgacccccc 180 acttctgcca gccagagaac aaaccccttt gactgtaatt ttccactacc tacccaaatc 240 ctataaaacg gccccaccgc tatcttcctt cgctgactct ctttttggac tcagcccgcc 300 tgcacccagg tgattaaaaa gctttattgc tcacataaag cctatttggt ggtctcttca 360 catggacgcg catggaa 377 <210> 112 <211> 453 <212> DNA <213> Homo sapiens <400> 112 gtcaggcctc tgagcccaag tcaagctatc gcatcccctg tgacttgcac gtatacgccc 60 agatggcctg aaataactga agaatcacaa aagaagtgaa tatgccctgg ccacacctta 120 actgatgaca ttccaccaca aaagaagtgt aaatggctgg tccttgcctt aactgatgac 180 attaccttgt gaaagtcctt ttcctggctc atcctggctc aaaaagcacc cccactgagc 240 accttgtgac ccccactcct gcccgccaga gaacaaaccc cctttgactg taattttcct 300 ttacctaccc aaatcctata aaacggcccc acccttatct ccctttgctg actctctttt 360 cggactcagc ccgcctgcac ccaggtgaaa taaacagcca tgttgctcac acaaagcctg 420 tttggtggtc tcttcacacg gacgcccatg aaa 453 <210> 113 <211> 5751 <212> DNA <213> Homo sapiens <400> 113 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac atatacatcc 60 agatggcctg aaataactga agaatcacaa aagaagtgat atttaaatgg cctgttcctg 120 ccttaactga tgacattcca ccacaaaaga agtgaaaatg gccggtcctt gccttaaatg 180 atgacattac cttgtgaaat tccttctcct ggctcatcct ggctcaaaaa gctccccgac 240 tgagcacctt gtgaccccca ctcctgcctg ccagagaaca accccctttg actgtaattt 300 tcctttagct acccaaatct tataaaacgg ccccactcca tctctcttca ctgactctct 360 tttcagactc agcccacctg cacccaggtg attaaaaagc tttattgctc acacaaagtc 420 tgtttggtgg ggtctcttca cacagacaca agtgaaattt tggtgccatg actcggatca 480 ggggaccttc cttgggagat caatcccctg tcctcctgct ctttgctcca tgagaaagat 540 ctacctacga cctcgggtcc tcagaccgac cagcccaagg aacatcacac caattttaaa 600 tccggtaagt ggcttctttt tactctcttc tccaacctct ctcactatcc ctcaacctct 660 ttctcctttc aatcttggcg ccacacttca atctctccct tctcttaatt tcagttcctt 720 tcctttcctc gtagagacag gagacacgtt ttatccgtgg acccaaaact ctggcgccgg 780 tcacggactc gggaagacag tcttcccttg gtgtttaatc atgcggggat gcctgcctga 840 ttattcaccc acatttcaga ggtgtctgac cacatgggga cgcctgcctt ggtccttcac 900 ccttaacggc aagtactgct tttctggggg gcaagaacct cccaacccct tcttcaccct 960 tagcggcaag taccgctttt ctagggggca agaacccccc accccttctc tccatgtctc 1020 tactctctct tttctctggg cttgcctcct tcactatggg cagccttcac ccctccattc 1080 ctccttctcc cttagcctgt gttctcaaga acctcttcaa ctcacacctg acctaaacct 1140 aaacgcctta ttttcttcta caataccgtt tggccccaat acaaactcga cagtggttcc 1200 aaatagccag aaaacggcac ttttgatttt tccatcctac aagatctaga taattcttat 1260 cataaaatgg gcaaacggtc cgagatgcct gacgtccagg cattctttta cacattgttc 1320 cctccctagt ctgttaccaa tgtgacttat cccagatcct ccttctttcc ttcccacctg 1380 tcccctcagt cccaacccca agcattgctg agtctttcta atcttccttt tctacagacc 1440 catctgacct ctctgctcct caccaggccg agccaggtcc caattcttcc tcagcttctg 1500 ctcccccacc ctataatcct tttatcacct ccactccttc cacccagtcc agcttacagt 1560 ttcgttctgt gactagcctt cccccaccag cccagcaatt tcctcttaaa aaggtggctg 1620 gagctaaagg catagtcaag gttaatgctc ctttttcttt atctgacatc tcccaaaatc 1680 agttagtgtt taggctcttt ttcatcaaat atgaaaaacc cagcccagtt catggctcat 1740 ttggcagcaa ccctgagacg ctttaaagcc ctagaccctg aaaggtcaga aggccgtctt 1800 attctcaata tgcattttat tttattaccc aatctgttcc tgacatgaaa taaagctcca 1860 aaaattaaat tctggccctc aaaccccaca acaggactta attaacctca cctttaaggt 1920 gtacaataat agagtagagg cagccaagta gcaatgtatt tctgagttgc aattccttgc 1980 ctccactgtg agacaagccc cagccacatc accagcatac aagaactcca aacgcctgaa 2040 ccacagctgc caggggttcc tctagaatct cctcccccag gagcttgcta caagtgccag 2100 aaatctggcc actggaccaa ggaatgccca cagcccagga ttcctcctaa gccatgtctc 2160 atctgtgcgg gaccccactg aaaatcagac tgttcaactt acctggcagc cactcccaga 2220 gcccctggaa ctctgaccca aggctctctg actgactcct tcccagatcc tctcggctta 2280 gcagctgaag actgacactg cccgattgcc tcagaagcct acaggaccat cacagatgct 2340 ctagataact ctcacagtgg agggtaagtc catccccttc ttaatcaata cagaggctac 2400 tcactccaca ttaccttatt ttcaagggcc tgtttccctt gcctccataa ctgtcgtggg 2460 tattgacagc caggcttcta aatctcttaa aactccccaa ctctggtgcc aatttagaca 2520 atactctttt aagcactcct ttttagttat ccccacctgc ccagttccct tatcaggcca 2580 agacacttta actaaattat ctgcttccct gactattcct gggctacagc cacacctcat 2640 tgccaccttt tctcccagtt caaagcctcc ttcacatcct ccccttgtat ctccccacct 2700 taacccacaa gtataagata cctctactct ctccttggtg accgatcatg tacccctacc 2760 atctcattac aacctaatca cccttaccct gctcaacgcc aatatcccat cccacagcac 2820 gctttaaaag gattaaagcc tgttatcact tgcctgttac agcatggcct tttaaagcct 2880 ataaactctc cttacagttc ccccatttta cctgtccaaa aacctgacaa gccttacagg 2940 ttagttcagg atctgcacct tatcaaccaa attgttttgc ctatccaccc catggtgcca 3000 aacccgtata ctctcctatc ctcaatacct ccctccacaa cccattattc tgttctggat 3060 ctcaaacatg ttttctctac tattcctttg cacccttcgt cccagcctct ctttgctttc 3120 acttggactg accctgacac ccatcaggct cagcaaatta cctgggctgt actgccgcaa 3180 ggcttcacgg acagcctcca ttacttcagt caagcccaaa tttcttcctc atctgttacc 3240 tatctcggca taattatcat aaaaacacac gtgctttccc caccgattgt gtccaactga 3300 tctctcaaac cccacacctt ctacaaaaca acaactcctt tccttcctag gcatggttgg 3360 atactttcga ctttggatac ctggttttgc cataacaaaa ccattatata aactcataaa 3420 aggaaaccta gctgaccccg tagatcctaa atcctttccc cactcctctt tccattcctt 3480 gaagagagct ttagagactg cccccaccct agctttccct gactcatccc aacccttttc 3540 attacccaca gccaaagtgc agggttgtgc agtcggaatt cttacacaag aaccgggact 3600 acgccctgta acctttttat ccaaacaact tgaccttact gttttgccta gccctcaagt 3660 ctgtgtgcag tggccaccac tgccctaata cttttagagg cccttaaaat tacaaactat 3720 gctcaactca ctctctacag ttctcataac ttccaaactc tattttcttc ctcacacctg 3780 acacatatac tttctgctcc ccggctcctt cagctgtact cactctttgt tgagtctccc 3840 acaattacca ttgttcctgg cctggacttc aatccggcct cccacattat tcctgatacc 3900 acacctgagc cccatgacta tatctctctg atccacctga cattcacccc atttccccat 3960 acttccttct ttcctgttcc tcacccagat cacacttggt ttattgatgg cagttccacc 4020 aggcctaatc gcaacacacc agcaaaggca ggccatgcta tagttcaagc cactagcctg 4080 cctcttagaa cctctgattt cctttccatc gtggaaatct attctcaaag aaataacttc 4140 tcagtcttcc atctgctatt ctactactcc tcagagatta ttcaggcccc ctcccttccc 4200 tacacatgaa gctcagggat ttgcccctgc ccaggaccgg caaattagct ttactcaaca 4260 tgccctgagt caggaaacta aaatacctct tggtcttggt agacactttc actggatagg 4320 tagaggcctt tcccacagga tctgagaaat gacccaccac ggtcatttct ttccttctgt 4380 cagacagaat tcctcggttt ggccttccca cctctataca gtcctgtaag ggaccggcct 4440 ttattagtca aatcacccaa gcagtttctc aggctcttag tattcagtga actaatggtc 4500 ttttaaaacc acaccttacc aagctcagcc accaacttaa aaaggactgg acaatacttt 4560 taccacttgc ccttctcaga attcgggcct gtccttggaa tgctacaagg tacagcccat 4620 ttgagctcct gtatagacgc tcctttttat taggccccag tctcattcca gacactagac 4680 caacttggac tgcacccccc accaaaaaaa aaaaaaaact tgtcgtccct actatcttct 4740 gtctagtcat actcctattc accattctca actactcata aatgccctgc tcttatttac 4800 actgccgatt tacactgttt ctccaagcca ccacagctga tgtctcctgg tgctatcccc 4860 aaaccgccac tcttaactcc ctcttaaagt aaataaatca tctttgccgg cagggctatg 4920 ctgaacttcc ttaggcactc tctagttaga tgtcctaggt cctcccaatt cttactcctt 4980 taatacctgt ttttctcctt gtcttattcc attatttttt caattcccac aaaattgtat 5040 ccaggccatc accaataatt ctataagaca aatgtttctt ctaacaaccc cacaatatcc 5100 ccccttacca caaaatcttc cttcagctta atctctccca ctctaggttc ccacgccacc 5160 cctaatcctg ctcgaagcat ccctgagaaa catcgcccat tatctctcca taccaccccc 5220 aaaaattttc gccaccccaa cacttcaaca ctattatgtt ttatttttct tactaatata 5280 agaagacagg aatgtcaggc ctctgagccc aagctaagcc atcatatccc ctgtgacctg 5340 cacgtataca cctagatggc ctgaagtaac tgaagaatca caaaagaagt gatatttaaa 5400 tggcctgttc ctgccttaac tgatgacatt ccaccacaaa agaagtgaaa atggccggtc 5460 cttgccttaa ctgatgacat taccttgtga aattccttct cctggctcat cctggctcaa 5520 aaatctcccc cactgagcac cctgtgaccc ccccactcct gcccgccaga gaacaactgc 5580 ctttgactgt aattttcctt tacctaccca aatcttataa aatgacccca cccctatctc 5640 tcttcactga ctctcttttc agactcagcc cacctgcacc caggtgatta aaaagcttta 5700 ttgctcacac aaagcctgtt tggtggtctc ttcacacgga tgcgagtgaa a 5751 <210> 114 <211> 976 <212> DNA <213> Homo sapiens <400> 114 gtggggaaaa gagagatcag attgttactg tgtctgtgta gaaagaagta gacataggag 60 actccatttt gttctgtatt aagaaaaatt cttctgcctt gagatgccgt taatctgtaa 120 ccttaccccc aaccctgtgc tccctgaaac atgtgctgtg tcaactcagg gttaaatgga 180 ttaagggctg tgcaagatgt gctttgttaa acaaatgctt gaaggcagca tgctccttaa 240 gagtcatcac cactccctaa tctcaaacca ctccctaatc tcaagtaccc agagacgcaa 300 aatactgcaa aggccgcagg gacctctgcc taggaaagcc aggtattgtc caaggtttct 360 ccccatgtga tagtctgaaa tatggcctcg tgggaaggga aagacctgac catcccccag 420 cccgacaccc ataaagggtc tgtgctgagg aggattagta aaagaggaag gaacacctct 480 ttgcagttga gataagagga aggcttctgt ctcctgctcg tctctgggca atggaatgtc 540 tgggtgtaaa gccgatttac tttacatgga atatacttcc atctactgag ataggggaaa 600 accgccttag ggctgtaggt atgacatgcg ggcagcaata ctgctcttta aggcattgag 660 atgtttatgt gtatacatat ctaaagcaca gcacttaatt ctttaccttg tttatgatgc 720 agagaccttt gttcatgtgt ttaccttctg accttctctc cactattatc ctattatcct 780 gccatgctcg ataatgatca ataaatacta agggaactca gaggccggtg ccagtgtgga 840 tcctctgtat gctgaatgct ggtcccctgg gcccactttt ctttctctat actttgtctc 900 tgtgtctctt ttccaagtct ctcgttccac ctaacgagaa acacccacag gtgtggaggg 960 gcaacccacc ccttca 976 <210> 115 <211> 302 <212> DNA <213> Homo sapiens <400> 115 tcaacccctg acctaactgg ttatttgcat aaaaaagcac tgtgaagatc cctgtcctat 60 tctgctctgt tctaattaca ggcgtatgca acccccagtc acttacccac tgcttgctca 120 atcgaacacg accctctcat gtggaccccc ttagagttgt gagcccttaa aatggacagg 180 attgctcact ccaggagctc ggctcttgag acaggagtct tgccgatgct cccagccaaa 240 taaacccctt ccttctttaa cttggtgttt gaggggtttc gtctgtggct cttcccgcta 300 ca 302 <210> 116 <211> 688 <212> DNA <213> Homo sapiens <400> 116 ttatagtagg tagctagtca ggcatgagca gggcaggaga gggttccacc tgaccaggaa 60 tgtcaggtga ccatcaggtg atggacagga ggttgttaaa tgtttctcta aaatagtaat 120 tggtcacagc cagtgaaagg gaaaggcagt ctccatatag atagaaaaaa acctgcaact 180 ggtgatcagc agcttcccaa taagatctga agagatgggt gagtgagctc aagcatgcac 240 attaagaggc aaaatggtgg agtttaactg gtatatgacc ttcctctagg aatgctagac 300 tggtaaggga agaatgcctc aagtgagtat gggcacaact ccagtaagca cactgcacag 360 gctcctctcc caagcgctag caggccactg cgcatgtgaa cagcccaccc caagggaaga 420 atcaggggag aagggacaca agaccctgga cgtaccaatg tataaaacct caagtcaaaa 480 ggccaaactg cacaataacc gttcgagtca ccagcttggc cctcttccag gtgcgcgttc 540 cttccttctg ttcctgctct aaaacttttt aataaatttt cactcctcta aaacttctcg 600 gtctccctac cttatgcccc tcggccgaat tctttcttct gaggaggtaa gaattgaggt 660 tgctgcagat gcatcagatt cgctactg 688 <210> 117 <211> 968 <212> DNA <213> Homo sapiens <400> 117 gtggggaaaa gcaagagaga tcagactgtt actgtgtcta tgcagaaaga agtagacata 60 agagactcca ttttgttctg tactaagaaa aattcttctg ccttgagatg ctgttaatct 120 gtaaccctac ccccaaccct gtgcagaaac atgtgctgtg tggactcaag gtttaatgga 180 tttaaggtta tgcaggatgc gctttgctaa acaaatgctt ggagtcagca tgcttgttaa 240 aagtcacaac cactccctaa tctcaagtac ccagggacac aaaacactgt ggaaggctgc 300 agggacctct gcctaggaaa gccaggtatt gtccaaggtt tctccccatg tgatagtctg 360 aaatatggcc tcgtgggaag ggaaagacct gaccatcccc cagcccgaca cccctaaagg 420 gtctgtgctg aggaggatta gtaaaagagg aagtcctctt tgcagttgag ataagaggaa 480 ggcatctgtc tcctgctgct cgtccctggg caagggaatg tctcagtgta aaaccggatt 540 gtatattcca tctactgaga taggagaaaa ccgccttagg gctggaggtg agacatgctg 600 gcagcaatac tgctctttaa tgcactgaga tgtttatata tgtgcacatc aaagcacaac 660 acctttttct taaccttgtt tatgacgcag agacatttgt tcacatgttt tagctgctga 720 ccctctcccc actactaccc tattgtcctg ccacatccac ttctctgaga tggtagagat 780 aatgatcaat aaatactgag ggaactcaga gactggtgct ggcgcaggtc ctctgtatgc 840 tgagcgcctg tcccctgggc tcatttttct ttctctatac tttttctctg tgtctctttc 900 ttatgtcagt ctcttgtccc acccgacgag aaacacccac aggtgtggag gggcaggcca 960 ccccttca 968 <210> 118 <211> 400 <212> DNA <213> Homo sapiens <400> 118 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac atacacatcc 60 agatggctgg ttcctgcctt aactgatgat attccaccac aaaagaagtg aaaatggccg 120 gttcctgcct taactgatga cactaccttg tgaaattcct tctcctggct catcctggct 180 caaaacgtcc cccgctgagc accttgtgat cctcacccct gcccaccaga gaacaacccc 240 cctttttcct ttacctaccc aaatcttata aaacggcccc actcctatct cccttcgctg 300 attctctttt cggactcagc ccacctgaaa cccaggtgaa atagccttgt tgctcacaca 360 aagcctgttt ggtggtctct tcacatggat gtgagtgaaa 400 <210> 119 <211> 1225 <212> DNA <213> Homo sapiens <400> 119 atggtaaata tgtatacaga ctctaagtat gcttatctag tcctccatgc ccactcagca 60 atatggagag aaaggaaatt cctaacttcc aagggaacac ctatcaaata tcaggaagcc 120 attaggagat tattattggc tgtacagaaa cctaaagagt tggcagtttt acactgctgg 180 ggtcatcaga aaggaaagga aagggaaata gaagggaacc gccaagcgga tattgaagta 240 aaaagagccg caaggcagga ccctccatta gaaatgctta tagaaggacc cctagtatgt 300 ggtaatccct tctgggaaac caagccccag tactcagcag gaaaaataga atagggaacc 360 tcacgaggac atagtttcct tcgctcagga tggctagcca ccgaagaagg gaaaatactt 420 ttgcctgcag ctaaccaatg gaaattactt aaaacccttc tccaagcctt tcacttaggc 480 attgatagca cccatcagag ggccaaatca ttatttacaa gaccaggcct tttcaaaact 540 atcaagcaga tagtcagggc ctgtgaagtg tgccaaagaa ataatcccct gcgctgcagg 600 ccatacattt caatccctgt atctttaacc tccttgttaa gtttgtctct tccagaatcg 660 aagctgtaaa actacaaata gttcttcaaa tggagcccca gatgtagtcc atgactaaga 720 tctaccacag acccctagac cagcctgcta gcctgtgctc tgatgttaat gacatcgaaa 780 gcacccctcc tgaggaaatc tcaactgcac aacccctact atgccccagt tcagcaggaa 840 gcagttagag cggtagtcgg ccaacctccc caactgcact tgagtttttc ctgttgagag 900 cggggactga gagacaagac tagctggatt tcctaggccg actaaaaatc cctaagccta 960 gctgggaagg tgaccgtgtc cacctttaaa cacggggctt gcaacttagc tcacacccaa 1020 accaatcaga gagctcacta aaatgctaat tagacaaaaa caggaggtaa agaaatagcc 1080 aatcatctat cacctgagag cacagcagga gggacaatga ccgggatata aacccaagca 1140 tttgagccag caatggcaaa cccctttggg tctcctgcct ttgtatggga gctctgtttt 1200 cactctatta aatcttgcaa ctgca 1225 <210> 120 <211> 3522 <212> DNA <213> Homo sapiens <400> 120 tgatctgatg tggaaagata taatgttact gctagatcag acactaaccc caaatgagag 60 aagtgccacc ataactgcag cctgagagtt tggcgacctc cagtatctca gtcaggtcaa 120 tgataggatg acaatagagg aaaaagcaac taagtcaaaa agcgaaaagg gagcttacta 180 actcaaaaat cttaaagtat ggggctattc tgttagaaaa aggtgattta acactaacca 240 ctgaaaattc ccttaaccca gcagatttcc taacagggga tttaaatctt aattaccata 300 caaaggtccg accagaccta agagtaactc tcttccggac aggacggact gatggctcct 360 cccaagcgat tgaggagaaa aaaacacaat gggtattcag taattgatag ggaaactctc 420 gtagaagcag agttagaaaa tttgcctaat aattggtctg ctcaaacgtg cggagctgtt 480 tgcactcagc caagccttaa agtacttata gaatcaaaaa tctctatctc aatcctgact 540 caaaaggtta cctacaacgt ctctgaaatg aatttgcata agaactgttg tttatgggaa 600 tgcatcttga tggggcagct gggttgttat gaaatactca ggaacccagc ccagctctag 660 gactcacccc tgagcacaaa ggcaatgttg ggcacgctgg taaaggatca ctagaatcca 720 gcagcctgga cctttctttg tggtcaagaa aggcaggaaa acaggtgcaa gacttctaca 780 tcggtaagcg taactaatcc gataagcaga ggtccatggg ttgttatgca tcctggaaag 840 gaataagcat taggaccata gaggacgctc taggactaaa gcgcatcaga aaatgactag 900 gggtgctggc atccctatgt tcttttttca gatgggaaac attcccccca aggcaaaaac 960 gcccctaaga tgtattctgg agagttcagc ccagtcagag tgcgtgcacc tttttctctc 1020 tcagacttaa agcaaattaa aatagactta ggtaaattct cagataacct tgagaattaa 1080 gttaggacaa tcctttgatc tgacatggag agatataatg tcactgctag atcagacact 1140 aacctcaaat gggagaagtg ccgccataac tgcagcctga gagtttggcg atctctggtg 1200 tctcagtcag gtcaatgata ggatgacaac ggaggaaaaa gaacaattcc ccacagccca 1260 gcaggcagtt cccagtgtag acactcattg agacacagaa tcagaacaca gagattggtg 1320 ccgcagacat ttgctaactt gtgtgctaaa aggacaggaa aactaggaag aagcctataa 1380 attattcaat gatgtccact ataacacagg gaaaggaaga aaatcctact gcctttctgg 1440 agagactaag ggaggcgttg aggaaacata gctctctgtc acctgactct attgaaggcc 1500 aactaatctt aaaggataag tttatcactc agtcagctgc agatattagg aaaaaaaact 1560 tcaaaagtct gccttaggcc cggagcaaaa cttagaaacc ctattgaact gggcaacctc 1620 ggttttttat aatagagatc aggaggagca ggtggaacgg gacaaacggg attaaaaaaa 1680 ggccaccgct ttagtcatgg ccctcaggca agcagacttt ggaggctctg gaaacgggaa 1740 aagctgggca aatcgaatgc ctaatagggc ttgcttccag tgtggtctac gaggacactt 1800 taaaaaagat tgtccaagta gaaataagcc gccccctcgt ccatgcccct tatgtcaagg 1860 gaatcactgg aaggcccact gccccagggg acgaaggtcc tctgagtcag aagccactaa 1920 ccagatgatc cagcagcagg actgagggtg cccagggcaa gtgccagccc atgccatcac 1980 cctcacagag ccctgggtat gcttgaccat tgagggccag gaggttaact gtctcctgga 2040 cactggcggc cttctcagtc ttactctcct gtcccagaca actgtcctcc agatctgtca 2100 ctatccgagg agtcctagga cagccagtca ctagatactt ctcacagcca ctaagttgtg 2160 actggggaat tttactcttt tcatatgcct ttctaattat gcctgaaagc cccactcctt 2220 tgatagggag agatatccta gcaaaagcag gggctatcat acactagaat taggagaagg 2280 aaaaagggta aatatatata cagactctaa gtatgcttac ctagtcctcc atgcccacgc 2340 agcaatatgg acagaaaagg aattcctaac ttccgaggga gcacctatca aatatccgga 2400 agccattagg agattattat tggctgtaca gaaacctaaa gaggtggcag tcttacactg 2460 ctggggtcat cagaaaggaa aggaaaggaa agggaaatag aagggaaccg ccaaatggat 2520 attgaagcca aaagagccac aaggcgggac cctccattag aaatgcttat agaaggaccc 2580 ctagtgtggg gtaaccccct ccaggaaacc aagccccagt actcagcaga agaaatagaa 2640 tggggaacct cacgaggaca tagttttctc ccctcaggat ggctagccac caaagaagga 2700 aaaatacttt tgcctgcagc taaccaatgg aaattactta aaatccttca ccaaaccttt 2760 cactctggca ttggtagcac ccatcagatg gccaaattat tatttactgg accaggcctt 2820 ttcaaaacta tcaagcagat agtcagggcc tgtgaagtgt gccaaagaaa taatcccctg 2880 cacttcaggc catacatttc aatccctgta tctttaacct ccttgttagg tttgtctctt 2940 ccagaatcga agctgtaaac tacaaatggt tcttcaaatg gagccccaga tgcagcccat 3000 gactaagatc tactggggtc ccctggactg gcctgctagc ccatgctccg atgttgatga 3060 catcgaaggc aaccctccag aggaaatctc aactgcacaa cccctacttc accccaattc 3120 agcagtaagc agttagagtg atcgtcggcc aacctccgca acagcacttg ggttttcctg 3180 ttgagagggg gaactgaaag acaggactag ctggatttcc taggccaact aataattcct 3240 aagcccagct gcgaaaggtg actgcaccta cctttaaaca cggggctagt aactcagctc 3300 acacccaact aatcaggtag taaagagggc tcactaaaat aaaaattagg ctaaagcagg 3360 aggtaaagaa atagtcaaat catatattgc ctgagagcac agagggaggg acaatgatcc 3420 ggatataaac ccaggcattc aagcagggag tggcaacccc ctttgagtcc cctcccatta 3480 tatgggagct ctgttttcac tctgttaaat cttgcaacta ca 3522 <210> 121 <211> 132 <212> DNA <213> Homo sapiens <400> 121 tgccaacgta taaaacccca agtcaaacca cacacttgac tctctcaagt cacccactta 60 gtcctcttcc aagtgtattt tacttccttt cattcctgct ctaaagcttt taaataaata 120 ttcactcctg ct 132 <210> 122 <211> 432 <212> DNA <213> Homo sapiens <400> 122 gtcacgcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac atatatgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aaggccctgc cctgccttaa 120 ctgatgacat tccaccattg tgatttgttc ctgccccacc ttaactgagt gattaaccct 180 gcgaatttcc ttgtcctggc tcagaagctc ccccactgag caccttgtga cccccgccca 240 tgcccaccag tgaacaaccc cctttgactg taattttcca ttaccttccc aaatcctata 300 aaacggcccc accccatctc cctttgctga ctctcttttc agactcagcc cgcctgcacc 360 caggtgaaat aaacagccat gttgctcaca caaagcctgt ttggtgatct cttcacacgg 420 acgtgcatga aa 432 <210> 123 <211> 497 <212> DNA <213> Homo sapiens <400> 123 gttatgaggt caccacttct cctgttgtcc ttctcagttt ctccccaacc tccccttttc 60 cctagtttat aagacaggag aaaagggaga aagcaaaaag ttggaaagaa acagaagtaa 120 gataaatagc tagacgactt tggcgccacc acctgaccct ggtggctaaa ataataataa 180 tattattaac ccctgaccaa aactactggt gttatctgta agttccagac attgaatgag 240 aaagcactgt aaaacttttt gttctgttag ctgatgtatg tagcccccag tcacgtttct 300 catgcttact tgatctatta tgactttttc aggtagaccc cttagagttg taagccctta 360 aaagggctag gaatttcttt ttcagggagc tcggctctta agacacgagt ctgccgatgc 420 tcccagctga ataaaaaaac ctcttccttc tttaatctgg tgtctgagga gttttgtctg 480 ctactcctcc tgctaca 497 <210> 124 <211> 4335 <212> DNA <213> Homo sapiens <400> 124 gtcaggtctc tgagcccaag ccaagccatc ccatcccctg tgacttgcac gtatacgccg 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aggccctgcc ccgccttaac 120 tgatgacatt ccaccattgt gatttgttcc tgccccacct taactgagtg actaaccctt 180 tgaatttcct tctcctggct cagaagctcc cccaccgagc accttgtgac ccccgcccct 240 gcccaccaga gaacaacccc ctttgactgt aattttcctt taccttccca aatcctataa 300 aacggcccca cccttatctc ccttcactga ctctcttttc ggactcagcc caaccgcatc 360 caggtgaaat aaacagcttt attgctcaca caaagcctgt ttggtggtct cttcacatgg 420 acacacatga aatttggtgc cgtgacttgg atcgggggac ctcccttggg agatcaatcc 480 cccgtcctcc tgctctttgc tccgtgagaa agatccatct acgacctcag gtcctcagac 540 cgaccagccc aagaaacatc tcaccaattt caaatccggt aagcggcctc tttttactct 600 cttctccaac ttccttcact atccctcaac ctctttctcc tttcaatctt gacaccacac 660 ttcaatctct cccttctctt aatttcaatt cctttcattt tcggatagag acaaaggaga 720 catgttttat ccgtggaccc aaaactccgg tgccggtcac ggactgggaa ggcagccttc 780 ccttggtgtt taatcattgc agggatgcct ctctgattat tcacccacat ttcaaaggtg 840 tcagaccacg cagggatgcc tgccttggtc cttcaccctt agccgcaagt cccgcttttc 900 tgggggaggg gcaagtaccc caaccccttc tctccatgtc tctacccctt ctctgctttt 960 ctgggggagg ggcaagtacc cctcaacccc ttctccttca cccttagtgg caagtcccgc 1020 ttttctaggg ggcaagaacc cccaatccct tatttccgtg ccccaaccct ttctctgctt 1080 ttctggaggg caagaaaccc ccatcacttc tccgtgtctc tactcttttc tctgggcttg 1140 cctccttcac tatggactag cttccacctt ccattcctcc ttcttctccc ttagcctgta 1200 ttcttaagaa cttaaaacct cttcaactct cacctgacct aaaatctaag cgtctttttt 1260 cttctgcaat gccgcttgac cccagtacaa actcgacagt agttacaaat tgccagaaaa 1320 acggcacttt caatttttcc atcctacaag acctaaataa ttcttgtcgt aaaacgggca 1380 aatggtctga ggtgcctgat gtccaggcat tcttttacac atcagtccct tcctagtctc 1440 tgcccaatgc aattcatccc aaatcttcct tctttccctc ccgcctgtcc cctcaggccc 1500 aaccccaagc gtcgctgagt ctttctaatc ttccttttct acagacccat ctgacctctc 1560 ccctcctcgc caggccgagc tagttcccaa ttcttcctca gcctctgctc ctccacccta 1620 taaacttttt atcgcctccc ctcctcacac ctgatccggc ttacagtttt gttccatgac 1680 tacccctccc ccacctgccc agcaatttac tcttaaaaag gtggctggag ccaaaggcat 1740 agtcaaggtt aatgctcctt tttctttatc ccaaatcaga agcgtttagg ctctttttca 1800 tcaaatataa aaacccagcc cagttcatgg ctcattcggc agcaaccctg agatgcttta 1860 cagccctaga ccctaaaagg tcaaaaggcc atcttattct caatatacat tttattaccc 1920 aatctgctcc tgacattaaa taaaactcca aaaattggaa tctggccctc aaaccccata 1980 acaggactta attaacctca ctttcaaggt gtacagtaat aaaacaaagt tgcaattcct 2040 tgcctccact gtgagacaaa ccccagccac atctccagca cacaagaact tccaaacgcc 2100 tgaacctcag tggccaggca ttcctccaga acctcctccc ccaggagctt gctacaagtg 2160 ccagaaatct gaccaccagg ccaagtaatg cccgcagccc aggattcctc ctaagccgtg 2220 tcccatctgt gtgggacccc agtggaaatc ggactgttca actcacctgg cagccactcc 2280 cagagcccct ggaactctgg cccaaggctc tctgactgac tccttcttgg cgtagcggct 2340 gaagactgat gctgcctgat cacctcagaa gccccataga ccatcacgga cgccgagctt 2400 taggtaactc tcacagtgga gggtaagtcc gtccccttct taatcaatat ggaggctacc 2460 cactccacat taccttcttt tcaagggcct gtttcccttg cctccataac tgttgtgggt 2520 attgacagcc aggcttctaa acctcttaaa actccccaac tctggtgcca acttagacaa 2580 tactctttta tgcactcttt tttagttatc cccacctgcc cagttccctt attaggccga 2640 gatattttaa ccaaattatc tgcttccctg actattcctg gactacagcc gcatctcatt 2700 gctgcccttc ttcccaatcc aaagcctcct ttgcatcctc ttcttgtatt cccccacctt 2760 aacccacaag tataagatac ctctactccc tccttggtga ccgatcatgc accccttatc 2820 atctcattaa aacctaatca cccttacccc gctcagtgcc aatatcccat tacagcatgc 2880 tttgaaagga ttaaagcctg ttatcactcg cctgctacag catggccttt taaagcctat 2940 aaactctcct tacaattccc ccattttacc tgtcctaaaa ccagacaagc cttacaagtt 3000 agctcaggat ctatgcctta tcaaccaaat tattttgcct atccacctca tggtaccaaa 3060 cccatatact ctactatcct caatacctcc ctccacaatc cattattctg ttctggatct 3120 caaacatgct ttctttacta ttcttttgca ccagtcatcc aagcctctct tcgctttcac 3180 ttggactgac cctgacaccc atcaggctca gcaaattacc tgggctgcac tgccacaagg 3240 cttcacagac agaccccatt acttcagtca agcgcaaatt tcatcctcat ctgttaccta 3300 tctcggcata attctcgtaa aaacacacat gctctccctg atgatcgtgt ccgattaatc 3360 tcccaaacct caatccctta caaaacaaca actcctttcc ttcctaggca tggttaatgt 3420 ggtcagaatt cttacacaag agccaggacc gcaccctgta gcctttctgt ccaaacaact 3480 tgaccttact gttttagcct agccctcatg tccgcgtgca gcggctgccg ctgctttagt 3540 acttttagag gccctcaaaa tcacaaacta tgctcaactc actctctaca tttctcataa 3600 cttccaaaat ctattttctt cctcatacct gacgcatata ctttctgctc cctggctcct 3660 tcagctgtac tcactctttg ttaagtccca caattaccat tgttcctggc ccggacttca 3720 atccagcctc ccacattatt ccagacacca cacctgaccc tcatgactgc atctctctga 3780 tccacctgat gttcatccca tttccccaca tttccttcgt ccctgtttct caccctgatc 3840 acgcttgatt tattgatggc agttccacca ggcctaatca ccacacacca gcaaaggcag 3900 gctatgctat agtacaagcc actagcccgc ctcttagaac ctttcatttc ctttccatcg 3960 tagaaatcta tcctcaagga aataacttct tagtgttcca tctgctattc catctgctac 4020 tcctcaagga ttattcaggc cccttcccta cacaacaagc tcgaggattt gcccccaccc 4080 aggactggca aattagcttt actcaacata ccccgagtcc caaaaactaa aatacctctt 4140 tgtctaagta gacactttca ctagataggt agaggccttt cctatagggt ctgagaaggc 4200 cactgcagtc atttcttccc ttctgtcaga cataattcct cagtttagcc ttcccacctc 4260 tatacagtct gataaaagac cagcccttat tagtcaaatc agtcaagcat ttttttaggc 4320 tcttagtatc cagtg 4335 <210> 125 <211> 3487 <212> DNA <213> Homo sapiens <400> 125 gtcaggcctc tgagcccaag ctaagccatc atgtcccctg tgacctgcat gtacacatcc 60 agatggccag ttcctgcctt aactgatgac attatcttgt gaaattcctt ctccttgctc 120 atcctggctc aaaaagctcc cctactgagc accttgtgac cccaaccctt cctgccagag 180 aacaaccccc tctttccttt acctacccaa atcctataaa atcgccccac cccatctccc 240 tttgctgact ctctttttgg actcagccca cctgaaccca ggtgaaataa acagctttat 300 tgctcacaca aagcctgttt ggtcgtctct tcacacggat gcatgtgaaa tttggtgctg 360 tgactcggac tgggggacct cccttgggag atcaatcccc tgtcctcctg ctctttgctc 420 tgtgagaaag atccacctat gacctcaggt cctcagactg accagcccaa gatacatctc 480 accaatttca aatctgggaa gcagcttctt tttactctct tctccaacct cccttactat 540 ccctcaacct ctttctcctt tcaatcttgg caccacactt caatctctcc cttctcttaa 600 tttcaattcc tttcattttc tggtagagac caagtagaca cgttttatcc atggacccaa 660 aactccggtg ccggtcacag actagggaag gcagccttcc cttggtgttt aatcattgca 720 gggacgcctc tctgattatt cacccaggtt tcagaggtgt cagaccacgc agggctgcct 780 gccttggtcc ttcaccctta gcagcaagtc ccgcttttct gagggaggcc caggaacccc 840 gacctgttat ctctgtgccc tgatccctta tttccatgcc ccaccctctt acctctgtgc 900 cctgatccct tatttccaca acctgacctc ctatctctgc accccaaccc tttatttctg 960 tgccccaacc cgtttcccac ttttctggaa ggcaagaatg ccccacccct tctcttcatg 1020 tctctattct ctcttttctc tgggcttgcc tccttcacta tgggcaagct tccgccctcc 1080 attccccttt cttctccctt agcctgtgtt cttaaaaacc taaaacctct tcaactcaca 1140 cctgacctaa aacctaaatg ccttattttc ttccacaatg ccacttgacc ccaatacaaa 1200 ctcgacagtg gttccaaata gccagaaaat gacactttca atttttccat cctacaagat 1260 ctagataatt cttgtcataa aatgggcaaa ttgtctgagg tgactgatgt ccaggcattc 1320 ttttacacat cggtccctcc ctagtctgtt cccagtgcaa ctcatcccaa atcttccttc 1380 tttccatccc acctgtcccc tcagtcccaa ccccaagcat cgctgactct ttctaatctt 1440 ccttttctac agacccatct gacctctccc ctcctcgcca ggctgagcta ggcctgaatt 1500 cttcctcagc ctctgctctt ccaccctata atccttttat cacctcccct cctcacactg 1560 ggtccggctg acagtttcgt tccatgacaa gccctcccca acctgcccag caatttcctc 1620 ttaaaaaggt ggctggagct aaaggcatag tcaaagttaa tgctcctttt tctttatccc 1680 aaatcagata aggtttaggc tctttttcat caaatataaa aataaacccc agttcatggc 1740 tcgtttggca gcaaccctga gatgttttag agccctagac cctaaaaggt caaaagaccg 1800 tcttattctt aatatacatt ttattaccca atctgctccc gacgttaaat aaaactccaa 1860 aaattaaatt cctgccctca aaccccacaa caggacttca ttaacctcgc cttcaaggtg 1920 tacaataata gagtagaggc agccaagtag caacatattt ctcagttgca attccttgcc 1980 tccactgtga gacaaacccc agccacatct ccagcacaca agagcttcca aacgcctaaa 2040 gcgcagtggc caggcattcc tccagaaccg cctcccccag gagcttgcta caagtgccgg 2100 aaatctggcc accaggccaa ggaatgcctg cagtccggga ttcctcctaa gccatgtccc 2160 atctgtacgg gaccccacta gaaatcggac tgttcaactc acctggcagc cactcccaga 2220 gcccctggga ctccagccca aggctccctg actgactcct tcccagatct tcttggctta 2280 gcagctgcag accgacactg cctgatcgat cgcctcggaa gcctacagga ccatcacaga 2340 cgctctaggt tactctcaca gtggagcgta agtctatccc cttcttaatc aatacggagg 2400 ctacccactc cacattacct tcttttcaag ggcctgtttc ccttgtctcc ataaccgttg 2460 tgggtattga cagccaggct tctaaacctc ttaaaactcc ccaactctgg tgcaacttag 2520 acaatactct tttaagcact cctttttagt tatccccacc tgcccagttc ccttattaag 2580 acgagacact tcaactaaac tatctgcttc cctgactatt cccggactac agatacatct 2640 cattgccacc caccgtaacc cacaagtaga agatacctct actccctcct tggcgaccta 2700 tcatgcaccc cttaccatct cattaaaatc taatcaccct taccccgctc aatgccaata 2760 tctcatccca cagcatgctt tgaaaggatt aaagcctgtt atcacttacc tgctacagca 2820 tggcctttta aagtctataa actctcctta caattccccc atcttacctg tcctaaaacc 2880 agacaagcct tacaagttag ttcaggatct atgacttatc aaccaaattg ttttgcctat 2940 ccaccccaag gtgccaaaca catatactct cctatcctca actcctccct ccacaacccc 3000 ttattctgtt ctggatctca aacatgcttt ctttactatt cctttgcacc cttcatccca 3060 gccactcttc gctttcactt ggactgaccc tgacacccat caggctcagc aaattacctg 3120 ggctgtactg ccgcaaagct tcacagacag cccccattac ttcagtcaag cccaaatttc 3180 ttccttatgt gttacctatc tcagcataat tctcataaaa ccacacgtgc tctccctgcc 3240 gatcgtgtgt gactaatctc tcaaacccca accccttcta caaaacaaca actcctttcc 3300 ttcccgggca tggttggata ctttcatctt tagatacctg gttttgccat cctaacaaaa 3360 ccattatata aactcacaaa aggaaaccta gctgacccca tagatcctaa atcctttccc 3420 cactcctctt tctgttcctt gaagacagct ttaaagactg cccccaccct agtcttggtt 3480 ccctgac 3487 <210> 126 <211> 356 <212> DNA <213> Homo sapiens <400> 126 gttaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcat gtacacgtcc 60 agatgcccag ttcctgtctt aactgatgac attaccttgt gaaattcctt ctcctggctc 120 atcctggctc aaaagctccc caactgagca ccttgtgacc cccacccctg cctgccagag 180 aacccccttt gactgtaatt ttcgtttacc tacccaaatc ttataaaaca gcctcacccc 240 tatctccctt cgcagactct ttttggactt agcccgcctg cacccaggtg aaataaacag 300 ccttgttgct cacacaaagc ctgtttggtg gtctctttac atggacacga gtgaaa 356 <210> 127 <211> 972 <212> DNA <213> Homo sapiens <400> 127 gtggggaaaa gaaagagaga tcagattgtt actgtgtctg tgtaggaaga agtagacata 60 agagactcca ttttgttctg tactaagaaa aattcttttg ccttgagacg ctgttaatct 120 gtaaccctac ccccaaccct gtgctcccta agacatgggc tgtgtcaact cagggttaaa 180 tggattaagg gctgttcagg gtgtgctttg ttaaacaaat gcttgaaggc agcatgcttg 240 ttaagagtca tcaccactcc ctaatctcaa gtacccagag acacactaca ctgcggaaga 300 ctgcagggac ctctgcctag gaaagccagg tattgtccaa ggtttctccc catgtcatag 360 tctgaaatac agcctcatgg gaagggaaag acctgactgt cccccagccc gacacccgta 420 aagggtctgt gctgaggagg attagtaaaa gaggaaggaa ggcctctttg cagttgagat 480 aagaggaagg catctgtctc ctgctcatcc ctgggcaatg gaatgtctcg gtgtaaagcc 540 cgattgtata ttccatctac tgagatagga gaaaaccgcc ttaggactgg aggtgggaca 600 tgctggcagc aatactgctc tttaaggcat tgagatgttt atgtatatgc acatcaaaag 660 cacagcactt ttttctttac cttgtttatg atgcagagac atttgttcac gtgtttacct 720 gctgatcttc tctccactat tatcctattg tcctgccaca tccccctctc cggaaacgcc 780 caataatgat caataaatac taagggaact cagaggccag tgcaggcatg ggtcctccgt 840 atgctgaacg ccagtcccct gggcccattt ttctttctct gtactttgtc tctgtgtctc 900 tttcttttcc aagtctctcc ttccacctaa cgagaaacgc ccacaggtgt ggaggggcaa 960 cccatccctt ca 972 <210> 128 <211> 972 <212> DNA <213> Homo sapiens <400> 128 gtggggaaaa gaaagagaga tcagattgtt actgtgtctg tgtaggaaga agtagacata 60 agagactcca ttttgttcgg tactaagaaa aattcttttg ccttgagacg ctgttaatct 120 gtaaccctac ccccaaccct gtgctcccta agacatgggc tgtgtcaact cagggttaaa 180 tggattaagg gctgttcagg gtgtgctttg ttaaacaaat gcttgaaggc agcatgcttg 240 ttaagagtca tcaccactcc ctaatctcaa gtacccagag gcacactaca ctgcggaaga 300 ctgcagggtc ctctgcctag gaaagccagg tattgtccaa ggtttctccc catgtgatag 360 tctgaaatac agcctcgtgg gaagggaaag acctgactgt cccccagcca gacacccgta 420 aagggtctgt gctgaggagg attagtaaaa gaggaaggaa ggcctctttg cagttgagat 480 aagaggaagg catctgtctc ctgctcgtcc ctgggcaatg gaatgtctcg gtgtaaagcc 540 cgattgtata ttccatttac tgagatagga gaaaaccgcc ttaggactgg aggtgggaca 600 tgctggcagc aatactgctc tttaaggcat tgagatgttt ctgtatatgc acatcaaaag 660 cacagcactt ttttctttac cttgtttatg atgcagagac atttgttaac gtgtttacct 720 gctgatcttc tctccactat tatcctattg tcctgccaca tccccctctc tggaaatgcc 780 cgataatgat caataaatac taagggaact cagaggccag tgccagcatg ggtcctccgt 840 atgctgaacg ccggtcccct gggcccattt ttctttctct gtactttgtc tctgtgtctc 900 tttcttttcc aagtctctcc ttccacctaa tgagaaacgc ccacaggtgt ggaggggcaa 960 cccatccctt ca 972 <210> 129 <211> 58 <212> DNA <213> Homo sapiens <400> 129 tgcctgtata tgccggcagc cccctagccc gctctttcac tggatatctg tgtctgag 58 <210> 130 <211> 968 <212> DNA <213> Homo sapiens <400> 130 gtggggaaaa gaaagagaga tcagactgtt attgtgtcta tgtagaaaga agtagacata 60 agagactcca ttttgttctg tactaagaaa aattcttttg ccttgagatg ctgttaatct 120 gtaaccctac ccccaaccct gagctcccag aaacatgtgc tctgtcaact caaggtttaa 180 tggattaagg gctatgcagg atgtgctttg ttaaacaaat gcttgaaggc agcattcttg 240 ttaaaagtca tcaccactcc ctactctctt gtacccaggg acacaaaaca ctgcagaagg 300 ccgcagggac ctctgcctag gaaagctagg tattgtccaa ggtttctccc catgtgatag 360 tctgaaatat ggcctcatgg gaagggaaag acctgaccgc cccccagccc aacacccata 420 aagggtcggt gctgaggagg attagtaaaa gaggaaggcc tctttgcagt tgagataaga 480 ggaaggcatc tatctcctgc tcgtccctgg ggcaatggaa tgtgttgatg taaaacctga 540 ttgtatattc catctactga gataggagaa aaccacctta gggttggagg tgagacatac 600 tggaagcaat actgctcttt aaggcgttga gatgtttatg tatatgcaca tcaaaagcgc 660 agcacttttt tctttacctt gtttatgatg cagagacatt tgttcacatg ttttcctgct 720 gaccttctct ccactattac cctattgtcc tgccacatcc ccctctgcga gaaacgccag 780 ataatgatca ataaatacta agggaactca gagactgggg ccggcgctgg tcctccgtat 840 gctgagcacc ggtcccctgg gcccactttt ctttctctat actttgtctc tgtgtctctt 900 tcttttctca agtctctcat tccacctgac gagaaatgcc cacaggtgtg gaggggcagc 960 ccacccct 968 <210> 131 <211> 5645 <212> DNA <213> Homo sapiens <400> 131 gtccagcctc tgagcccaag ctaaaccatc atatcccctg tgacctgcac atacacatcc 60 agatgggcga ttcctgcctt aactgatgac attccaccac aaaagaagtg aaaatggcct 120 gttcctgcct taactgatga cattaccttg tgaaattcct tctcttggct catcctggct 180 taaagctccc ccgctgagca ccttgtgacc ccccccccaa cccctgcccg ccacagaaca 240 aacccccttt gactgtaatt ttcctttatc tacccaaatc ttataaaatg gccccacccc 300 tatctccctt cgctggctct cttttcggac tcagcccacc tgcccccagg tgaaataaac 360 agccttgttg ctcgcacaaa gcctgtttcg tggtctcttc acatggatgc gagtgaaatt 420 ttggtgccgt gactcggatc gggggacctc ccttgggaga tcaatccccc gtcctgctct 480 ttgctccgtg agaaagatcc acctacgacc tctggtcctc agaccgacca ggccagggaa 540 catctcacca attttaaatc aggtaagcga cctcttttta ctctcttctc caacctctca 600 ctatccatca acctctttct cctttcaatc ttggcaccat ctttcaatct ctcccttctc 660 ttaatttcag ttccttccct tttctggtag agacaactca ggagatgcat tttatccatg 720 aacccaaaac tccggcgcca gtcacagact cgggaaggca gccttccctt ggtgtttaat 780 cacgtgggga tacctgcctg attattcaca cacatttcag gtgtgtctga ccacgcgggg 840 acgcctgcct tggtccttca cccttagcgg caaatgccgc ttttctgggg gacaagaacc 900 ccctgacccc ttctctccgt gtctctactc tctcttttct ctggacttgc ctccttcact 960 atgggcaacc ttccaccctc cattcctccc tctactccct tagcctgtgt tctcaagaac 1020 ttaaaacctc ttcaactcac acctgaccta aaacctaaat gccttatttt cttctacaat 1080 gcaatctgac cacaatacaa actcgacagt ggttccaaat agccagaaaa aggcgctttc 1140 gatttttcca tcctacaaga tctaaataat tcttgtcata aaatgggcaa acggtctgag 1200 gtgcctgaca tccaggcatt cttttacaca tcagtgcctc cctagtctct gttcccaatg 1260 cgactagtcc caaatcctcc ttctttccct cccgcctgtc ctctcagtcc caaccctaag 1320 ggtcgctgag tatttgtaat cttccttttc tacagaccca tctgacttct cccctcctcc 1380 ccaggctgct cctcgccagg ccaagccagg tcccaattct tcctcagcct ctgctccccc 1440 accctgtaac ccttttatca cctcccctcc tcacacccgg tccagcttac agtttcgttc 1500 agcaactagc cctccccgac ctgtccagca atttcctctt aaaaaaggtg gctggagcta 1560 aaggcatagt cgaggttaat gctccttttt ctttatccga cctctcccaa aatcagttag 1620 catttaggct ctttttcatc aaatatgaaa aacccagccc agttcatggc tcattcggca 1680 gcaaccctga gatgctttat agccctagac cctaaaaggt caaaaggcca tcttattctc 1740 aatatacatt ttattaccaa atccgctcct gacattaaat aaaactccaa aaattaaatt 1800 ccggccctca aaccccacaa acaagacata attaacctcg ccttcaaggt gtacaataat 1860 agagtagagg aagccaagta gcaatatatt tctgagttgc aattccttgc ctccactgtg 1920 aaagaaaccc cagccacatc tccacacaca agaacttcca aacgcctgaa ctgcagctgc 1980 caaggtttac tccggaaatc tggccactgg gccaaggaat gcccacagcc cgagattccc 2040 cctaagccgt gtcctgtctg tgcgggaccc cactgaaaat cggactcttc aactcacctg 2100 gcagccgctt ccagatcccc tggaactctg gcccaaggct ctctgagtga ctccttccca 2160 gatcttctcg gcttagcagc tgaagactga cactgcccaa tcgccttgga agcctacagg 2220 acaatcacag atgctctggg taactctcac agtggagggt aagtccatcc ccttcttaat 2280 caatacggag gctacccact ccacattact tcttttcaag ggcctgtttc ccttgcctcc 2340 ataactgttg tgggtattga cggccaggct tctaaacctc ttaaaactcc ccaactctgg 2400 tgcccactta gacaacattc ttttatacac tcttttttaa gttatcccca cctgcccagt 2460 tcccttatta ggccaagaca ttttaactaa attatctgtt tccctgacta ttcctggact 2520 acagcaacac ctcattgcca cccttttccc catttcaaag cctccttcac atcctcctct 2580 cgtatccccc caccttaacc cacaagtata ggacacctct actccctcct tggtgactgg 2640 tcatgcaccc cttaccatcc cattaaaacc taatcaccct tacccccctc aatgccaata 2700 tcccatccca cagcatgctt taaaaggatt aaagcctgtt atcacttgcc tgttacagca 2760 tggcctttta aagcctataa actctcctta caattccccc attttacctg tcctaaaacc 2820 agacaaggct tacaggttag ttcaggatct gcgccttatc aaccaaattg ttttgcctat 2880 ccaccctgtg gtgccaaacc catatactct cctagcctca atgcccccct ccacaaccca 2940 ttattctgtc tggatttcaa acatgctttc tttactattc ctttgcaccc ttcatcccag 3000 cctctcttcg ctttcacttg gactgaccct gacacccatc aggctcagca aattacctgg 3060 gctgtgctgc cgcaaggctt cacagacggc ccccattact tcaatcaagc ccaaatttct 3120 ttcaatcaag cccaaatttc ttcctcatct gttacttatc tcggcgtaat tctcataaaa 3180 acacacatgc tctccctgcc gattgtgtcc aactgatctc tcaaacccca acaccttcta 3240 caaaacaata actcctttcc ttcctaggca tggttagata ctttcgactt tagacacctg 3300 gttttgccat cctaacaaaa ccattatata aactcacaaa aagaaaccta tctgacccca 3360 tagatcctaa atcctttccc cactcctctt tccgttcctt gaagacagct ttagagactt 3420 cccccaccct aactctccct gactcatcag aacccttttc attacccaca gctgaagtgc 3480 aggactgtgc agtcagaatt cttacacaag aactgggacc acaccctgta gcctttttat 3540 cccaacaact tgaccttact gttttgccta gccctcaagt ctgcgtgcgg cagctgccgc 3600 tgccctaata cttttagagg cccttaaaat cacgaactat gatcaacagt tctcataact 3660 tccaaaatct attttcttcc tcacacctga cacatatact gtctgctccc tggcttcttc 3720 agctgtactc actctttgtt gagtctccca caatcaccac tgttcctggc ccggacttca 3780 atccagcctc ccacattatt ccagatacca cacctgaccc ccacgactgt atctctctga 3840 tccacctgac attcacccca tttccccata tttccttctt tcttgttcct caccctgatc 3900 acacttagtt tattgatggc agttcccacc aggcctaatc gccacacacc agcaaaggca 3960 ggctatgcta tagtacaagc cactaccccg cctcttagaa cctctcattt catttccatc 4020 gtggaaatct atcctcaagg aaataacttc tcagtgttcc atctgctatt ctactactcc 4080 tcagggatta ttctggcccc ctcccttccc tacacatgaa gctcggagat ttgcccccac 4140 ccaggactgg caaattagct ttactcaaca tgccccaagt caggaaacta aaatacctct 4200 tggcctgggt agacattttc actggatagg tagaggactt tcccacaggg tctaagaagg 4260 ccaccatggt catttcttcc cttctgtcag acataattcc tcagtttggg cttcccacct 4320 cttcacagtc tgataacaga ccagcgttta ttagtcaaat cagccaagca ttttttcaga 4380 ctcttggtat tcagtgaaac ctttacatcc cttaccatcc tcaatcttca ggaaaggtag 4440 aatggactaa tggtccttta gaaacacacc tcaccaatct cagccaccaa cttaaaaagg 4500 actgtacaat acttttacca cttgcccttc tcagaattca ggcctgtcct cggaatgcta 4560 caggttatag cccatttaag ctcctgtatg gatgctcctt tttattaggc cccagtctca 4620 ttccagatac cagaccaact tggactgtgc cccaaaaaac ttgtcatccc tactatcttc 4680 tctctagtca tactcctatt cactgttctc aactactcct gcatgccctg ctcttgttta 4740 cactgccggt ttacactgtt tctccaagcc atcacagctg atatctcctg gtgctatccc 4800 caaactgcca ctcttaactc ttaacgtaaa taaataatct ttgctggcaa ggctatgctg 4860 aacctcctta ggcactctct aattagatgt cctgggtcct cccaattctt agtcctttaa 4920 tacctgtttt tctccttctc ttattccatt tagttttcaa ttcatacaaa accatatcca 4980 ggccatcacc aataattcta cacaacaaat gtttcttcta acaaccccac aatatcaccc 5040 cttaccacaa aatcttcctt cagcttaatc tctcccactc caggttccca tgccgcccca 5100 atcccgctcg aagcagtcct gagaaacatc acccattatc tctccatacc acccccaaaa 5160 attttcgccg ccccaacact ttacaactat ttcggttttt tttttttctt attaatataa 5220 gaagacagga atgtcaggcc tctgagccca agctaagcca tcatatcccc tgtgacctgc 5280 acatacacat ccagatggcc agttcctgcc ttaactgatg agattccacc acaagagaag 5340 tgaaaatggc ctgttcctgc cttaactgat gacattacct tgtgaaattc cttctcctgg 5400 ctcacctggc tcaaaagctc ccccgccaag caccttgtga cccccacccc tgaccaccag 5460 agaacaaccc ccctttgact gtaattttcc tttacctacc caaatcttat aaaatggccc 5520 cacccctatc tcccttcgct gactctcttt tttggactca gcccacctgc acctggctga 5580 aataaacagc cttgttgctc acacaaagcc tgtttggtgt tctcttcaca gggacgtgag 5640 taaaa 5645 <210> 132 <211> 397 <212> DNA <213> Homo sapiens <400> 132 gtcaggcctc tgagcccaag ctaagccatc atatcccgtg acctgcaggt atacatccag 60 atggcctgaa gtaactgaag aatcacaaaa gaagtgaaaa tggcctattc ctgccttaac 120 tgatgacatt atcttgtgaa attccttctc ctggctcatc ctggctcaaa agctccccca 180 ctgagcacct tgtgaccccc acccctacca gctagagaac aacccccttt gactgaattt 240 tcctttacct acccaaatcc tataaaaggg ccccatccct gtctcccttt gctgactctc 300 tttttggact cagcccgcct gcacccaggt gaaatgaaca gccttgttgc tcacacaaag 360 cctgtttggt ggtctcttca catggatgca agtgaaa 397 <210> 133 <211> 6501 <212> DNA <213> Homo sapiens <400> 133 gtggggaaaa gcaagagaga tcagattgtt actgtgtctg tgtagaaaga agtagacata 60 ggagactcca ttttgttatg tactaagaaa aattcttctg ccttgagatt ctgttaatct 120 ataaccttac ccccaaccct gtgctctctg aaacatgtgc tctgtcaact cagagttaaa 180 tggattaagg gcggtgcaag atgtgctttg ttaaacagat gcttgaaggc agcatgctcc 240 ttaagagtca tcaccactcc ctaatctcaa gtacccaggg acacaaaaac tgcggaaggc 300 cgcagggacc tctgcctagg aaagccaggt attgtccaag gtttctcccc atgtgatagt 360 ctgaaatatg gcctcgtggg aagggaaaga cctgaccgtc ccccagcccg acacccgtaa 420 agggtctgtg ctgaggagga ttagtataag aagaaggcat gcctcttgca gttgagacaa 480 gaggaaggca tctgtctcct gcctgtccct gggcaatgga atgtctcggt ataaaacccg 540 attgtatgct ccatctactg agatagggaa aaaccgcctt agggctggag gtgggacctg 600 cgggcagcaa tactgctttg taaagcattg aaatgtttat gtgtatgcat atctaaaagc 660 acagcactta atcctttacc ttgtctatga tgcaaagacc tttgttcacg tgtttgtctg 720 ctgaccctct ccccacaatt gtcttgtgac cctgacacat ccccctcttc gagaaacacc 780 cacagatgat caataaatac taagggaact cagaggctgg cgggatcctc catatgctga 840 acgctggttc cccgggtccc cttctttctt tctctatact ttgtctctgt gtctttttct 900 tttccaaatc tctcgttcca ccttacgaga aacacccaca ggtgtgtagg ggcaacccac 960 ccctacatct ggcgcccaac gtggggcttt tctctagggt gaaggtacgc tcgagcgtgg 1020 tcattgagga caagtcgacg agagatcccg agtacttcta cagtcagcct tacggtaagc 1080 ttgtgcactc ggaagaagct agggtgataa tggggcaaac taaaagtaaa gttaaaagta 1140 aatatgcctc ttatctcagc tttattaaaa ttcttttaaa aagaggggga gttaaagtat 1200 ctacaaaaaa tctaatcaag ctatttcaaa taatagaaca attttgccca tggtttccag 1260 aacaagaaac tttagatcta aaagattgga aaagaattgg taaggaacta aaacaagcag 1320 gtaggaaggg taatatcatt ccacttacag tatggaatga ttgggccatt attaaagcag 1380 ctttagaacc atttcaaaca gaagatagcg tttcagtttc tgatgccact ggaagctgta 1440 taatagattg taatgaaaag acaaggaaaa aatcccagaa agaaaccgaa agtttacatt 1500 gcgaatatgt agcagagccg gtaatgactc agtcaacgca aaatgttgac tataatcaat 1560 tacaggaggt gatatatcct gaaacgttaa aattagaagg aaaaggtcca gaattagtgg 1620 ggccatcaga gtctaaacca cgaggcacaa gtcctcttcc agcaggtcag gtgcctgtaa 1680 cattacaacc tcaaacgcag gttaaagaaa ataagaccca accgccagta gcctatcaat 1740 actggccacc ggctgaactt cagtatcggc cacccccaga aagtcagtat ggatatccag 1800 gaatgccccc agcaccacag ggcagggcgc cataccctca gccgcccact aggagactta 1860 atcctacggc accacctagt agacagggta gtgaattaca tgaaattatt gataaatcaa 1920 gaaaggaagg agatactgag gcatggcaat tcccagtaac gttagaaccg atgccacctg 1980 gagaaggagc ccaagaggga gagcctctca cagttgaggc cagatacaag tctttttcga 2040 taaaaatgct aaaagatatg aaagagggag taaaacagta tggacccaac tccccttata 2100 tgaggacatt attagattcc attgctcatg gacatagact cattccttat gattgggaga 2160 ttctggcaaa atcgtctctc tcaccctctc aatttttaca atttaagact tggtggattg 2220 atggggtaca agaacaggtc cgaagaaata gggctgccaa tcctccagtt aacatagatg 2280 cagatcaact attaggaata ggtcaaaatt ggagtactat tagtcaacaa gcattaatgc 2340 aaaatgaggc cattgagcaa gttagagcta tctgccttag agcctgggaa aaaatccaag 2400 acccaggaag tacctgcccc tcatttaata cagtaagaca aggttcgaaa gagccctacc 2460 ctgattttgt ggcaaggctc caagatgttg ctcaaaagtc aattgccgat gaaaaagccc 2520 gtaaggtcat agtggagttg atggcatatg aaaacgccaa tcctgagtgt caatcagcca 2580 ttaagccatt aaaaggaaag gttcctgcag gatcagatgt aatctcagaa tatgtaaaag 2640 cctgtgatgg aatcggagga gctatgcata aagctatgct tatggctcaa gcaataacag 2700 gagttgtttt aggaggacaa gttagaacat ttggaggaaa atgttataat tgtggtcaaa 2760 ttggtcactt aaaaaagaat tgcccagtct taaataaaca gaatataact attcaagcta 2820 ctaccacaac aggtagagag ccacctgact tatgtccaag atgtaaaaaa ggaaaacatt 2880 gggctagtca atgtcgttct aaatttgata aaaatgggca accattgtcg ggaaacgagc 2940 aaaggggcca gcctcaggcc ccacaacaaa ctggggcatt cccaattcag ccatttgttc 3000 ctcagggttt tcagggacaa aaaccccccc tccctgtccc aagtgtttca gggaataagc 3060 cagttaccac aatacaacaa ttgtcccccg ccacaagcgg cagtgcagca gtagatttat 3120 gtactataca agcagtctct ctgcttccag gggagccccc acaaaaaatc cccacagggg 3180 tatatggccc cctgcctgag gggactgtag gactaatctt gggaaaatca agtctaaatc 3240 taaaaggagt tcaaattcat actggtgtgg ttgattcaga ctataaaggc gaaattcagt 3300 tggttattag ctcttcaatt ccttggagtg ccagtccagg agacaggatt gctcaattat 3360 tactcctgcc atatattaag ggtggaaata gtgagataaa aagaacagga gggtttggaa 3420 gcactgatcc aacaggaaag gctgcatatt gggcaagtca ggtctcagag aacagacctg 3480 tgtgtaaggc cattattcaa ggaaaacagt ttgaagggtt agtagacact ggagcagatg 3540 tctctatcat tgctttaaat cagtggccaa aaaattggcc taaacaaaag gctgttacag 3600 gacttgtcgg cataggcaca gcctcagaag tgtatcaaag tacggagatt ttatattgct 3660 tagggccaga taatcaagaa agtactgttc agccaatgat tacttcaatt cctcttaatc 3720 tgtggggtcg agatttatta caacaatggg gtgcggaaat catgcccgct ccattatata 3780 gccccacgag tcaaaaaatc atgaccaaga tgggatatat accaggaaag ggactaggga 3840 aaaatgaaga tggcattaaa gttccagttg aggctaaaat aaatcaagaa agagaaggaa 3900 tagggtatcc tttttagggg cggccactgt agagcctcct aaacccatac cattaacttg 3960 gaaaacagaa aaaccggtgt gggtaaatca gtggccgcta ccaaaacaaa aactggaggc 4020 tttacattta ttagcaaatg aacagttaga aaagggtcat attgagcctt cattctcgcc 4080 ttggaattct cctgtgtttg taattcagaa gaaatcaggc aaatggcgta tgttaactga 4140 cttaagggcc gtaaacgccg taattcaacc catggggcct ctccaacccg ggttgccctc 4200 tccggccatg atcccaaaag attggccttt aattataatt gatctaaagg attgcttttt 4260 taccatccct ctggcagagc aggattgtga aaaatttgcc tttactatac cagccataaa 4320 taataaagaa ccagccacca ggtttcagtg gaaagtgtta cctcagggaa tgcttaatag 4380 tccaactatt tgtcagactt ttgtaggtcg agctcttcaa ccagttagag aaaagttttc 4440 agactgttat attattcatt atattgatga tattttatgt gctgcagaaa cgaaagataa 4500 attaattgac tgttatacat ttctgcaagc agaggttgcc aatgctggac tggcaatagc 4560 atctgataag atccaaacct ctactccttt tcattattta gggatgcaga tagaaaatag 4620 aaaaattaag ccacaaaaaa tagaaataag aaaagacaca ttaaaaacac taaatgattt 4680 tcaaaaatta ctaggagata ttaattggat tcggccaact ctaggcattc ctacttatgc 4740 catgtcaaat ttgttctcta tattaagagg agactcagac ttaaatagta aaagaatatt 4800 aaccccagag gcaacaaaag aaattaaatt agtggaagaa aaaattcagt cagcgcaaat 4860 aaatagaata gatcccttag ccccactcca acttttgatt tttgccactg cacattctcc 4920 aacaggcatc attattcaaa atactgatct tgtggagtgg tcattccttc ctcacagtac 4980 agttaagact tttacattgt acttggatca aatagctaca ttaatcggtc agacaagatt 5040 acgaataata aaattatgtg gaaatgaccc agacaaaata gttgtccctt taaccaagga 5100 acaagttaga caagccttta tcaattctgg tgcatggcag attggtcttg ctaattttgt 5160 gggaattatt gataatcatt acccaaaaac aaagatcttc cagttcttaa aaatgactac 5220 ttggattcta cctaaaatta ccagacgtga acctttagaa aatgctctaa cagtatttac 5280 tgatggttcc agcaatggaa aagcagctta cacagggccg aaagaacgag taatcaaaac 5340 tccatatcaa tctgctcaaa gagcagagtt ggttgcagtc attacagtgt tacaagattt 5400 tgaccaacct atcaatatta tatcagattc tgcctatgta gtacaggcta caagggatgt 5460 tgagacagct ctaattaaat atagcatgga tgatcagtta aaccagctat tcaatttatt 5520 acaacaaact gtaagaaaaa gaaatttccc attttatatt actcatattc gagcacacac 5580 taatttacca gggcctttga ctaaagcaaa tgaagaagct gacttactgg tatcatctgc 5640 actcataaaa gcacaagaac ttcatgcttt gactcatgta aatgcagcag gattaaaaaa 5700 caaatttgat gtcacatgga aacaggcaaa agatattgta caacattgca cccagtgtca 5760 agtcttacac ctgcccactc aagaggcagg agttaatccc agaggtctgt gtcctaatgc 5820 attatggcaa atggatgtca cgcatgtacc ttcatttgga agattatcgt atgttcatgt 5880 aacagttgat acttattcac atttcatatg ggcaacttgc caaacaggag aaagtacttc 5940 ccatgttaaa aaacatttat tgtcttgttt tgctgtaatg ggagttccag aaaaaatcaa 6000 aactgacaat ggaccaggat attgtagtaa agctttccaa aaattcttaa gtcagtggaa 6060 aatttcacat acaacaggaa ttccttataa ttcccaagga caggccatag ttgaaagaac 6120 taatagaaca ctcaaaactc aattagttaa acaaaaagaa gggggagaca gtaaggagtg 6180 taccactcct cagatgcaac ttaatctagc actctatact ttaaattttt taaacattta 6240 tagaaatcag actactactt ctgcagaaca acatcttact ggtaaaaaga acagcccaca 6300 tgaaggaaaa ctaatttggt ggaaagataa taaaaataag acatgggaaa tagggaaggt 6360 gataacgtgg gggagaggtt ttgcttgtgt ttcaccagga gaaaatcagc ttcctgtttg 6420 gatacccact agacatttga agttctacaa tgaacccatc ggagatgcaa agaaaagggc 6480 ctccacggag atggtaacac c 6501 <210> 134 <211> 3490 <212> DNA <213> Homo sapiens <400> 134 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgaccttcat gtacacatcc 60 agatggccgg ttcctgcctt aactgatgac attatcttgt gaaattcctt ctccttgctc 120 atcctggctc aaaagctccc ctactgagca ccttgtgacc cccactcctg cctgccagag 180 aacaaccccc ctttttcctt tacctaccca aatcctataa aatggcccca ccccatctcc 240 cttcactgac tctctttttg gactcagccc acctgaaccc aggtgaaata aacagcttta 300 ttgctcacac aaagcctgtt tggtggtctc ttcacatgga tgcatgtgaa atttggtgct 360 gtgactcgga ttgggggacc tcccttggga gatcaatccc ctgtcctcct gctctttgct 420 ctgtgagaaa gatccaccta cgacctcagg tcctcagact gaccagccca agaaacatct 480 caccaatttc aaatctggga agcagcttct ttttactctc ttctccaact tccctcacta 540 tccttcaacc tctttctcct ttcaatcttg gcaccacact tcaatttctc ccttctctta 600 atttcaattc ctttcatttt ccggtagaga ccaaggagac acgttttatc tgtggaccca 660 aaactccggt gccggtcgcg gactagggaa ggcagccttc ccttggtgtt taatcattgc 720 agggacgcct ctctgattat tcacccaggt ttcagaggtg tcataccacg cagggacacc 780 tgccttggtc cttcaccctt agcagcaagt cctgcttttc tgggggaggc acaggaaacc 840 caccctctta tctctgcacc ccgatccctt atttccatgc cccgccctct tatctctgtg 900 ccctgatccc ttatttccac aacctgacct cctatctctg caccccaacc ctttatttct 960 gtgccccaac ccatttcctg cttttctgga aggcaagacc accccacccc ttctctttgt 1020 gtctctactc tctcttttct ctaggcttgc ctccttcact atgggcaagc ttccactctc 1080 cattcccctt tcttctccat tagcctgtgt tcttcaaaac ctaaaacctc ttcaactcac 1140 acctgaccta aaacctaaat gccttatttt cttctacaat gccgcttgac cccaatacaa 1200 actcaacagt ggttccaaat agccagaaaa tggcactttc aatttttcca tcctacaaga 1260 tctagataat tcttgtcata aatgggcaaa tggtctgagg cgcctcacgt ccaggcattc 1320 ttttacacat cggtccctcc ctagtctctg ttcccaaagc aactcatccc aaatcttctt 1380 tctttccctc ccacctctcc cctcagtccc aaccccaagt gtctctgagt ctttctaatc 1440 ttccttttct acagacccat ctgacctctc cccttcttgc caggctgagc taggtcccaa 1500 ttcttcctca gcctctgctc ctccacccta taatcctttt atcacctcct ctccttacac 1560 tgggtctggc ttacagtttc attccatgac tagccctccc caacctgccc agcaatttac 1620 tcttaaaaag gtggctggag ctaaaggcat agtcaaggtt aatgctcctt tttctttatc 1680 ccaaatcaga taaggtttag gctcttttgc atcaaatata aaaatccgcc ccagttcatg 1740 gctcgtttgg cagcaaccct gagacgcttt acagccctag accctaaaag gtcaaaaggc 1800 cgtcttattc tcaatataca ttttattacc caatctgctc ccgacattaa ataaaattcc 1860 aaaaattaaa ttccggccct caaaccccat aacaggactt aattaacctc gccttcaagg 1920 tgtacaataa tagagtacag gcagccaagt agcaacatat ttctcagttg caattccttg 1980 cctccactgt gagacaaacc ccagccacat ctccagcaca caagagcttc caaacgccta 2040 aagcgcagtg gccaggcgtt cctccagaat cgcctctccc aggagcttgc tacaagtgcc 2100 agaaatctga ccaccaggcc aaggaatgcc tgcagcccgg gattcctcct aagccatgtc 2160 ccatctgtgc gggaccccac tagaaatcgg actgttcagc tcacctggca gccactccca 2220 gagcccctgg aactccagcc caaggctctc tgactgactc cttcccagat cttcttggct 2280 tagcagctgc agaccgacac tgcccaatcg atcgcctcgg aagcctacag gaccatcaca 2340 gacgctctag gttactctca cagtggagtg taagtccatc cccttcttaa tcaatacaga 2400 ggctacccac tccacattac cttcttttca agggcctctt tcccttgcct ccataactgt 2460 tgtgggtatt gacagccagt cttctaaacc tcttaaagct ccccaactct ggtgccaact 2520 tagacaatac tcttttaagc actccttttt agttatcccc acctgcccag ttcccttatt 2580 aggccgagac acttcaacta aattatctgc ttccctgact attcccggac tacagataca 2640 tctcattgcc acccacctta acccagaagt agaagatacc tctactccct ccttggcgac 2700 ctatcatgca ccccttacca tctcagtaaa acctaatcat ccttaccccg ctcaatgcca 2760 atatctcatc ccacagcatg ctttgaaagg attaaagcct gttaccactc acctgctaca 2820 gcatggcctt ttaaagccta taaactctcc ttacaattcc cccatcttac ctgtcctaaa 2880 accagacaag ccttacaagt tagttcagga tctatgactt atcaatcaaa ttgttttgcc 2940 tatccacccc aaggtgccaa acacatatac tctcatatcc tcaattcctc cctccacaac 3000 ccattattct gttctggatc tcaaacatgc tttctttact attcctttac acccttcatc 3060 ccagccactc ttcgctttca cttggactga ccctgacacc catcaggctc agcaaattac 3120 ctgggctgta ctgctgcaaa gcttcacaga cagcccccat tacttcagtc aagcccaaat 3180 ttcttcctta tctgttacct atctccgcat aattctcata aaaacacacg tgctctccct 3240 gccgatcgtg tgtgactaat ctctcaaacc ccaacccctt ctacaaaaca acaactcctt 3300 tccttcctgg gcatggttgg atactttcat ctttagatat ctggttttgc catcctaaca 3360 aaaccattat ataaactcac aaaaggaaac ctagctgacc ccatagatcc taaatccttt 3420 cctcactcct ctttctgttc cttgaagaca gctttaaaga ctgcccccat cctagtcttg 3480 gttccctgac 3490 <210> 135 <211> 414 <212> DNA <213> Homo sapiens <400> 135 gtcaggcctc tgagcccagg cctgcacgaa tacatccaga tggcctgagg caactgaaga 60 accacaaaag aagtgaaaat ggccggttcc tgccttaact gatgacattc cacccttgtg 120 atttgctcct gccccaccct aactgatgaa ttaaccttgt gacattcctt ctcctggaca 180 atgaatatca gagccttctc accagcacct tgtgaccccc actcctgcac cttgtgaaca 240 acccccttta actgtaattt tccactacct acccaaatcc tataaaactg cctcacccct 300 atctcccttt gctgactccc ttttcggact cagtccgcct gcacccaggt gattaaaaag 360 ctttattgct cacacaaagc ctatttggtg ttctcttcac acagacgggc ataa 414 <210> 136 <211> 2741 <212> DNA <213> Homo sapiens <400> 136 tgggtcaggt gcaaagtaag cccaccccac tgggacctat gttaaaaaaa ttttttttca 60 agagagaatt taaaggagat tacggtgtta gtatgacacc aggaaaactt agaactttgt 120 gtgaaataga ctggctagca ttagaggtag gttggccacc agaaggaagc ctggacaggt 180 cccttgtttc aaaggtatgg cacaaggtaa cctgtaagcc aaagcaccca gaccggtttc 240 tgtacataga cagttacagc tggttttaga ccccctttcc cccaccacag tagttaagag 300 aacagcagca taagcggctg gcagagccaa ggaacgacca gaaaagagaa aaagaggcca 360 tctgtaccaa ttctaagagt ttagactaaa caagttctta ttaatagcaa aggataattg 420 aaatctcaaa cttacaaggt tttcaacaaa agtgaagttt gctaaaagtt aacagtgtaa 480 catgtatttt ggtaacttct aatcttgtgg ccttagacag tctagtccaa agacataaag 540 aaagttcgct tttttaaaaa ggaaagaaaa ggggggaggc agaatttata ttaaaaaaaa 600 gttatatggt aaattcttgt cctgaaataa attaactggt tgtttaaaga aaaaaaagtt 660 tgttaatcag tcaaaaaatt gagacatgtt aaaaaattgt ctgggaaagt cgtgagaaaa 720 aaattataaa aaaaaatttt tatgcaaaaa atattgtata atttaaaagt aatgaggcct 780 cctgagtact atttaaaaaa aaaaaaccag ttcatgtgca agatgtataa gaaaagtaaa 840 atataccttt ggtaaaaaaa aaaattataa aggggcataa acgtggattt ttacctacat 900 taaaaggtta aaaaaattat tgttttaaaa gtttaagcaa gctttaaaac gttaattata 960 aaaaaaattc tgtgtgtaaa catattagct aaggttaaaa aggtatcatc cagtttttct 1020 gtgaactgga cattaaagta aaaatgcaag aggtttttct taaagcatca acctgctctt 1080 taacaaaaat tataaaaggt taaaaagagt ctataaaatc ttaccttatg gtcaaacata 1140 aaaaattgga taaatatgtc tacaaggttt tattaaaatt aagtttaaca ttaataacac 1200 actaatataa aggtaaaatt tagcttatct ggtataaaag tcatacagga agcattagta 1260 aatataaaat agtgtttagc tttcttttgt ctaaaaacta ataaaaattg gtgctaaagg 1320 aagcattcat tttactagag gatcataaaa gttaaagact taaaacaaac tttggcaatt 1380 aagacagcat accaagatgc aaatgcctgg ttgaaatgga tcaaatattc catctgcagg 1440 ttaaacaaaa gcaattagca tgcttgtgca catggcaggc cagaggccct gattgtcccc 1500 cttccactaa ggtggtcctc cagtcggcca ggcatgggct gcatggtagc tcttttccag 1560 gattctatag cctggagtaa taagtcatgc caagctctct ctgctatatc ccaaagtccc 1620 tgcaggtcag cccccgaggg ccatccagct tccatctccc aacactaagt tcactacgtg 1680 tctctcatgg cagggaggag acttagcatt ccttggagac ctgaagggat gcagtgagct 1740 taagaatttt caagagctta tcaatcagtc agcccttgtt catcccaaag cggatgtgtg 1800 gtggtattgt ggtagacctt tattggggac tctgccgagt aactagagtg gcacttgtgc 1860 tttagtccat ttggctatcc ctttcaccct gacatttcat caacaagagg aaaaaataat 1920 aataagaaga agacatcata aagcgagaaa agctccttat aggtctttca actctcacat 1980 ctatttagat gcaattgaag ccccgcaagg agtcccagat caatttaaag cttgaaatca 2040 aatagttaca ggatttaagt caatattttg gtagatgaca gtcaataaaa atgtagatta 2100 gataaactac atctattaca accaacagca acgagctttt catgagttaa aaagaaaaac 2160 tcatgtcggc cccagccctg aggctacctg acctgacaaa actctttacg ctctatgtgt 2220 cagaaacaaa aaaaatggca gttagagttt taacccagac tgtagggccc tggccaaggc 2280 cagtggccta tctctcaaaa caactagatg gggtttccaa aggctggccc ccatgtccaa 2340 gggccctggt agcaacggcc ctgtcacaag aagcagataa gctaactctt acacaaaacc 2400 taaacataaa ctccccccat gctgtggtga ttttaataaa taccaaagga caccatgcta 2460 gatgaatgct agactaacta gatgccaaag ctagctctgt gaaaatcccc acataaccat 2520 tgacgtttgc acaccctaaa ccctgccacc ttcctcctgg tatcagagag cccagttaac 2580 catatctgga ctcagtttat tctagtaggc ccaaccaccg agaccaccct taaacatcag 2640 taggctggga gctgtacatg gatgggagca gcttcgccaa cccctgcaaa gtgactctga 2700 agaagacgac aagccctgct ccagtcacac ctggaagctg a 2741 <210> 137 <211> 72 <212> DNA <213> Homo sapiens <400> 137 aaggccgcct tattcttaat aggcattgca tcacccagtc agctcctgac attagaaaaa 60 agcttcaaaa at 72 <210> 138 <211> 5924 <212> DNA <213> Homo sapiens <400> 138 tggggcaaac taaaagtaaa attaaaagta aatatgcctc ttatctcagc tttattaaaa 60 ttcttttaaa aagaggggga gttaaagtat ctacaaaaaa atctaatcaa gctatttcaa 120 ataatagaac aattttgccc atggtttcca gaacaaggaa ctttagatct aaaagactgg 180 aaaagaattg gtaaggaact aaaacaagca ggtaggaagg gtaatatcat tccacttata 240 gtatggaatg attgggccat tattaaagca gctttagaac catttcaaac agaagaagat 300 agcgtttcag ttcctgacgc ccctagaagc tgtatagtag attgtaatga aaagacaagg 360 aaaaaatccc agaaagaaat ggaaagttta cattgcgaat atgtagcaga gccggtaatg 420 gctcagtcaa cgcaaaatgt tgactataat caattacagg aggtgatata tcctgaaacg 480 ttaaaattag aaggaaaagg tccagaatta gtggggccat cagagtctaa gccacgaggg 540 ccaagtcctc ttccagcagg tcaggtgccc gtaacactac aacctcaaac gcaggttaaa 600 gaaaataaga cccaaccgcc agtagcttat caatactggc cgccagccga acttcagtat 660 cggccacccc cagaaagtca gtatggatat ccaggaatgc ccccagcacc acagggcagg 720 gcgccatacc ctcagccgcc cactaggaga cttaatccta cggcaccacc tagtagacag 780 ggtagtgaat tacatgaaat tattgataaa tcaagaaagg aaggagatac tgaggcgtgg 840 caattcccag taacgttaga accgatgcca cctggagaag gagcccaaga gggagagcct 900 ctcacagttg aggccagata caagtctttt tcgataaaaa tgctaaaaga tatgaaagag 960 ggagtaaaac agtatggacc caaatcccct tatatgagga cattattaga ttccattgct 1020 catggacata gactcattcc ttatgattgg gagattctgg caaaatcgtc tctctcaccc 1080 tctcaatttt tacaatttaa gacttggtgg attgatgggg tacaagaaca ggtccgaaga 1140 aatagggctg ccaatcctcc agttaacata gatgcagatc aactattagg aataagtcaa 1200 aattggagta ctattagtca acaagcatta atgcaaaatg aggccattga gcaagttaga 1260 gctatctgcc ttagagcctg ggaaaaaatc caagacccag gaagcgcctg cccctcattt 1320 aatacagtaa gacaaggttc gaaagagccc taccctgatt ttgtggcaag gctccaagat 1380 gttgctcaaa agtcaattgc caatgaaaaa gcccgtaagg tcatagtgga gttgatggca 1440 tatgaaaacg ccaatcctga gtgtcaatca gccattaagc cattaaaagg aaaggttccc 1500 gcaggatcag atgtaatctc agaatatgta aaagcctgtg atggaatcag aggagctatg 1560 cataaagcta tgcttatggc tcaagcaata acaggagttg ttttaggagg acaagttaga 1620 acatttggag gaaaatgtta caattgtggt caaattggtc acttaaaaaa gaattgccca 1680 gtctcaaata aacagaatat aactattcaa gcaactacaa caggtagaga gccacctgac 1740 ttatgtccaa gatgtaaaaa aggaaaacat tgggctagtc aatgtcgttc taaatttgat 1800 aaaaatgggc aaccattgtc gggaaacgac caaaggggcc agcctcaggc cccacaacaa 1860 actggggcat tcccaattca gccatttgtt cctcagggtt ttcagggaca acaaacccac 1920 tgtcccaagt gtttcaggga ataagccagt taccacgata caacaattgt cccccgccac 1980 gagcggcagt gcagcagtag atttatgtac tatacaagca gtctctctgc ttccagggga 2040 gcccccacaa aaaatcccca cagaggtata tggcccactg cctgagagga ctgtaggact 2100 aatcttggga agatcaagtc taaatctaaa aggagttcaa attcatactg gtgtggttga 2160 ttcagactat aaaggcgaaa ttcagttggt tattagctct tcaattcctt ggagtgccag 2220 tccaggagac aggattgctg aattattact cctgccatat attaagggtg gaaatagtga 2280 aataaaaaga acaggagggt ttggaagcac tgatccgaca ggaaaggctg catattgggc 2340 aagtcaggtc tcagagaaca gacctgtgtg taaggccatt attcaaggaa aacagtttga 2400 agggttggta gacactggag cagatgtctc tatcattgct ttaaatcggt ggccaaaaaa 2460 ttggcctaaa caaaaggctg ttacaggatt tgtcggcata ggcacagcct cagaagtgta 2520 tcaaagtact gagattttac attgcttagg gccagataat caagaaagta ctgttcagcc 2580 aatgattact tcaattcctc ttaatctgtg gggtcgagat ttattacaac aatggggtgc 2640 ggaaatcatg cccgctccat tatatagccc cacgagtcaa aaaatcatga ccaagatggg 2700 atatatacca ggaaagggac taggaaaaaa tgaagatggc attaaagttc cagttgaggc 2760 taaaataaat caagaaagag aaggaatagg gtatccttgt taggggcagc cactgtagag 2820 cctcctaaac ccataccatt aacttggaaa acagaaaaac cggtgtgggt aaatcagtgg 2880 ccgctaccaa aacaaaaact ggaggcttta catttattag caaatgaaca gttagaaaag 2940 ggtcacattg agccttcgtt ctcgccttgg aattctcctg tgtttgtaat tcagaagaaa 3000 tcaggcaaat ggcgtatgtt aactgactta agggccgtaa acgccgtaat tcaacccatg 3060 gggcctctcc aacccgggtt gccctctctg gccatgatcc caaaagactg gcctttaatt 3120 ataattgatc taaaggattg cttttttacc atccctctgg cggagcagga ttgcgaaaaa 3180 tttgccttta ctataccagc cataaataat aaagaaccag ccaccaggtt tcagtggaaa 3240 gtgttacctc agggaatgct taatagtcca actatttgtc agacttttgt aggtcgagct 3300 cttcaaccag ttagagacaa gttttcagac tgttatatta ttcattatat tgatgatatt 3360 ttatgtgctg cagaaacaaa agataaatta attgactgtt atacatttct gcaagcagag 3420 gttgccaatg caggactggc aatagcatct gataagatcc aaacctctac tccttttcat 3480 tatttaggga tgcagataga aaatagaaaa attaagccac aaaaaataaa aataagaaaa 3540 gacacattaa aaacactaaa ttattttcaa aaattgctgg gagatattaa ttggattcgg 3600 ccaactctag gcattcctac ttatgccatg tcaaatttgt tctctatctt aagaggagac 3660 tcagacgtaa atagtaaaag aatgttaacc ccagaggcaa caaaagaaat taaattagtg 3720 gaagaaaaaa ttcagtcagc gcaaataaat agaatagatc ccttagcccc actccaactt 3780 ttgatttttg ccactgcaca ttctccaaca ggcatcatta ttcaaaatac tgatcttgtg 3840 gagtggtcat tccttcctca cagtacagtt aagactttta cattgtactt ggatcaaata 3900 gctacattaa ttggtcagac aagattacga ataataaaat tatgtggaaa tgacccagac 3960 aaaatagttg tccctttaac caaggaacaa gttagacaag cctttatcaa ttctggtgca 4020 tggcagattg gtcttgctaa ttttgtggga attattgata atcattaccc aaaaacaaag 4080 atcttccagt tcttaaaatt gactacttgg attctaccta aaattaccag acgtgaacct 4140 ttagaaaatg ctctaacagt atttactgat ggttccagca atggaaaagc agcttacaca 4200 gggccgaagg aacgagtaat caaaactcca catcaatcgg ctcaaagagc agagttggtt 4260 gcagtcatta cagtgttaca agattttgac caacctatca atattatatc agattctgca 4320 tatgtagtac aggctacaag ggatgttgag acagctctaa ttaaatatag catggatgat 4380 cagttaaacc agctattcaa tttattacaa taaactgtaa gaaaaagaaa tttcccattt 4440 tatattactc atattcgagc acacagtaat ttaccagggc ctttgactaa agcaaatgaa 4500 caagctgact tactggtatc atctgcattc ataaaagcac aagaacttca tgctttgact 4560 catgtaaatg cagcaggatt aaaaaacaaa tttgatgtca catggaaaca ggcaaaagat 4620 atcgtacaac attgcaccca gtgtcaagtc ttacacctgc ccactcaaga ggcaggagtt 4680 aatcccagag gtctgtgtcc taatgcatta tggcaaatgg atgtcacgca tgtaccttca 4740 tttggaaaat tatcatatgt tcatgtaata gttgatactt attcacattt catatgggca 4800 acttgccaaa caggagaaag tacttcccat gttaaaaaaa catttattgt cttgttttgc 4860 tgtaatggga gttccggaaa aaatcaaaac tgacaatgga ccaggatatt gtagtaaagc 4920 tttccaaaaa ttcttaagtc agtggaaaat ttcacataca acaggaatgc cttataattc 4980 ccaaggacag gccatagttg aaagaactaa tagaacactc aaaactcaat tagttaaaca 5040 aaaagaagca ggagacagta aggagtgtac cactcctcag atgcaactta atctagcact 5100 ctatacttta aattttttaa acatttatag aaatcagact actacttctg cagaacaaca 5160 tcttactggt aaaaagaaca gcccacatga aggaaaacta atttggtgga aagataataa 5220 aaataagaca tgggaaatag ggaaggtgat aacgtggggg agaggttttg cttgtgtttc 5280 accaggagaa aatcagcttc ctgtttggat acgcactaga catttgaagt tctacaatga 5340 acccatcgga gatgcaaaga aaagcacctc cgcggagacg gagacaccac agtcgagcac 5400 cgttgactca caagatgaac aaaatggtga cgtcagaaga acagatgaag ttgccatcca 5460 ccaagaaggc agagccgcca acttgggcac aactaaagaa gctgacgcag ttagctacaa 5520 aatatctaga gaacacaaag gtgacacaaa ccccagagag tatgctgctt gcagccttga 5580 tgattgtatc aacggtggta agtctcccta tgcctgcagg agcagctgca gctaactata 5640 cctactgggc ctatgtgcct ttcccgccct taattcgggc agtcacatgg atggataatc 5700 ctatagaagt atatgttaat gatagcgtat gggtacctgg ccccacagat gatcgctgcc 5760 ctgccaaacc tgaggaagaa gggatgatga taaatatttc cattgggtat cgttatcctc 5820 ctatttgcct agggagagca ccaggatgtt taatgcctgc agtccaaaat tggttggtag 5880 aagtacctac tgtcagtccc atcagtagat tcacttatca catg 5924 <210> 139 <211> 3476 <212> DNA <213> Homo sapiens <400> 139 ggctctggaa aagggaagag ctgggcaaac tgaatgctaa tagggcttgc ttccagtgcg 60 gtctacaagg acactttaaa aaagattgtc caaatagaaa taagccgccc cctcgtccat 120 gtcccttatg tcaagggaat cactggaagg cccactgccc caggggatga aagtcctccg 180 agtcagaagc cactaaccag atgatccagc agcaggactg agggtgcccg ggccaagtgc 240 cagcccatgc catcaccctc acagaacccc gggtatgctt gaccattgag ggtcaggagg 300 ttaactgtct cctggatgct ggcacgacct tctcagtttt actctcctgt cccagacaac 360 tgtcctccag atctgtcact atccaaaggg tcctaggaca ggcagtcact agatacttct 420 cccagccact aagctgtgac tggggaactt tattcttttc atatactttt ctaattatgc 480 ctgaaagccc cactcccttg ttagggagag acattctagc aaaagcaggg gccattatac 540 acctgaacat aggagaaaga acatccattt gttgtcccct gcttgaggaa ggaattaatc 600 catcctgaag tctgggcaac agaaggacaa tatggacgaa caaagaatgc ctgtcctgtt 660 caaattaaac taaaggattc tgcctccttt ccctaccaaa ggcagtaccc tcttagaccc 720 aaggcccaac aaggactcca aaaaattgtt aaggacctaa aagcccaagg cctagtaaaa 780 ccatgcaata gctcctgcaa tactccaatt ttaggagtac agaaacccaa cagacagtgg 840 aggtcagtgc aagatctcag gattatcaat gaggctctta tccctctata cccagctgta 900 cctaaccctt gtactctgct ttcccaaata ccagaggaac cagagtggtt tacagtcatg 960 gaccttaagg atgccttttt ctgcatccct gtacatccca actctcaatt cttctttgcc 1020 tttgaagatc cttcaaaccc aacgtctcaa ctcacctgga ctgtcttatc ccaagggttc 1080 agggatagcc cccatctatt tggccaggca ttagcccaag actttagcca gttctcatac 1140 ttggacactc ttgtcctttg gtacgtggat gatttacttc tagccgccca ttcagaaacc 1200 ttgctccatc aagccaccca agcgctttta aacttccttg ccacttgtgg ctacaaggtt 1260 tccaaaccaa aggctcagct ctgcttacag caggttaaat acttaaggct aaaattatcc 1320 aaaggcacta gggccctcag tgaggaatgt atccagcata tactggctta tcctcatccc 1380 aaaaccctaa agcaactaag agggctcctt ggcataacag gcttctgccg aatatggatt 1440 cccaggtatg gcaaaatagt caggccatta aatacactaa ttaaggaaac tcagaaagcc 1500 aatacccatt tagtaagatg gacacctgaa gcagaagcgg ctttccaggc cctaaggaag 1560 gccctaaccc aagccccagt gttaagcttg ccaacggggc aagacttttc tttatatgtc 1620 acagaaaaaa aataggaata gctctaggag tccttacaca ggtctgaggg accagcttgc 1680 aacctgtggc atacttgagt aagaaaattg atgtagtggc aaagggttgg cctcattgtt 1740 tacaggtagt ggcagcagta gcagtcttag cctccgaagc agttaaaata atacaaggaa 1800 gagatcttat gtgtgtggac atctcatgat gtgaacagca tactcactgc taaaggagac 1860 ttgtggctgt cagacaacca ttagcttaaa tatcaggctc ttatttgaag ggccagtgct 1920 gcgactgcgc acttgtgcaa ctcttaaccc agccacgttt cttccagaca atgaagaaaa 1980 gatagaacat aactgtcaac aggtgattgc tcaaacctac gccgctcgag gggaccttct 2040 agaggttccc ttgactgatc ccaacctcaa cttgtatact gatggaagtt cctttgtgaa 2100 aaaaggactt caaaaagtgg agtatgcagt ggtcagtgat aatagaatac ttgaaagtaa 2160 tcccctcact ccaagaacta gcattcagct ggcaaaacta atagccctca ctcgggcatc 2220 agaattagga aaaggaaaaa tggtaaatat atatacagac tctaagtatg cttacctagt 2280 cctccatgcc cacacagcaa tatggagaga aagggaattt ctaacttccg agaacaccta 2340 tcaaacatca ggaagccatt aggagattat tattggctct acagaaacct aaagaggtgg 2400 cagtcttaca ctgccggggt catcagaaag gaaaggaaag ggaaatagaa gggaaccgcc 2460 aagcggatat tgaagccaaa agagctgcaa ggcgggaccc tccattagaa atgcttatag 2520 aaggacccct cttatggggt aaccccctcc aggaaaccaa gccccaatac tcagcagaag 2580 aaatcgaatg gggaacctca cgaggacata gtttcctccc ctcaggatgg ctagccacga 2640 aagaaggaaa aatacttttg cctgcagcta accaatggaa attacttaaa acccttcacc 2700 acacctttca cttaggcatt gatagcaccc atcagatggc caaatcatta tttactggac 2760 caggcctttt caaaactatc aagcagatag tcaaggcctg tgacgtgtgc caaagaaata 2820 atcccctgca ctgcagggta ttatttgaat acatttgaat ccctgtatct ttaacctcct 2880 tgttaagttt gtctcttcca gaatcaaagg tgtaaaacta caaatcgttc ttcaaatgga 2940 gccccagatg cagtccatga ctaagatcta ccgaggaccc ctggaccagc ctgctagacc 3000 atgctccaat gttgatgaca tcgaaggcac ccctcccaag gacccctgca tgacccctac 3060 tacactccaa ttcagcagga agcagttaga gcggttgtcg gccaacctcc ccaagagcac 3120 ttgggttttc ctgttgagag gaggtaccga gagacaagac tagctggatt tcctaggccg 3180 actaagaatc cccaagccta gctgggaagg tgacgcatcc acctttaaac acagggcttg 3240 caacttagct cacacccaac caatcaagta gtaaagagag ctcactaaaa tgctaattag 3300 gcaaaaacag gaggtaaaga aatagccaaa catctatcgc ctgcctgaga gcacagggga 3360 aggaacaatg atcgggatat aaacccaggc atttgagctg gcaatggcta cccactttgg 3420 gtcccctccc tttgtatggg agctctgttt tcactctatt acatcttgca actgca 3476 <210> 140 <211> 6181 <212> DNA <213> Homo sapiens <400> 140 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac gtatacatcc 60 agatggcctg aagtaactga agaatcagaa aagaagtaat atttaaatgg cctgttcctg 120 ccttaactga tgacattcca ccacaaaaga agtgaaaatg gctggtcctt gccttaactg 180 atgacattac cttgtgaaat tccttctcct ggctcatcct ggcctaaaaa gctccctgac 240 tgagcacttt gtgaccccca ctcctgcctg ccagagaaca acccctcttt ttcctttacc 300 tacccaaatc ttataaaaca gccccacccc tatctccctt tgctgactct ctttttggac 360 tcagcctgcc tgcacccagg tgaaataaac agccttgttg ctcacacaaa gcctgtttgg 420 tggtctcttc acatggatgc gagttaaatt ttggtgctgt gactcagatc aggggacctc 480 ccttggcaga tcaatcccct gtcctcctgc tctttgctcc gtgagaaaga tccacctaca 540 acctcagatc ctcagactga cctgcccaag gaacaccaca cccattttaa atcaggtaag 600 cggcctcttt ttactctctt ctccaacctc tctcactatc cctcaacctc tttctccttt 660 caatcttggc gccacacttc agtctctccc ttctcttaat ttcagttcct ttccttttct 720 catagagaca ggagacgcat tttatccgga cccaaaactc cggcgccagt cacggactca 780 ggaagacagt cttcccttgg tgtttaatca catggggatg cctgcctgat tattcatcca 840 cgtttcagag gtgtctgacc acgcgaggaa gcctgccttg gtccttcacc cttagtggca 900 agtaccactt ttctgggggg caagaacccc ccgacccctt ctctccatgt ctctatccct 960 tctctgcttt tctagggggc aagaaccccc tgactccttc tctccatgtc tctacccctt 1020 ctctgctttt ctggaaggca agaacccccc agccccttct ccttcaccct tagcagcaag 1080 tactgctttt ctagggggca acaacccccc caaccccttc tctccgtgtc tctactgctt 1140 ctccactttt gtggggggca agaacccccc aacccctcct ctccgtgtct ctaccccttt 1200 tccactttcc tgggggcaag caccccccac cccttctctc cgtgtctcta ctctctcttt 1260 tctctgggct tgcctccttc actatgggca gccttccacc ctccattcct ccttcttctc 1320 ccttagcctg tgttctcaag aacttaaaac ctcttcaact cacacctgac ctaaacctaa 1380 atgccttatt tttcttctac aatgccgctt gaccccaata taaactcgat agttgttcca 1440 aatagccaga aaacagcact ttcaattttt ccatcctaca agatctagat aattcttatt 1500 gtaaaatagg caaatagtct gaggtgcctg acgtccaggc attcttttac acattgttcc 1560 ctccctagtc tctgttccca atgtgactca tcccaaatcc tccttctttc cctcccgcct 1620 gtcttcccag tcccaacccc aagcgtcgct gagtctttct aatcttcctt ttctacagac 1680 ccatctgact tctccccttc tccccaggct gctcctagcc aggctgagcc aagtcccaat 1740 tcttcctcag cctctgatcc cccacactat aatcctttta tcacctccct tcctcacacc 1800 gggtccagct tacagtttcc ttccacaact agccctcccc cacctgccca gcaatttcct 1860 cttaaaaagg tggctggagc tagaggcata gtcaaggtta atgctccttt ttctttatca 1920 gacctctccc aaaatcagtt agcatttagg ctctttttca tcaaatatga aaaacccagc 1980 ccagttcatg gcttgttcgg cagcaaccct gagacgcttt acagccctag accctaaaag 2040 gtcaaaaggc catcttattc tcaatataca ttgtattacc caatctgctc ctgacattaa 2100 ataaaactcc aaaaattaag ttccagccct caaaccccac aacaggactt aattaacctc 2160 accttcaagg tgtacaataa tagagtagag gtagccaagt agcaatgtat ttctgagttg 2220 caattccttg cctccactgt gagacaaacc ccagccatat ctccagccca caactccaaa 2280 tgcctgaact gcagctgccg ggggttcctc cagaacctcc tcccccagga gcttgctaca 2340 catgccagaa atctggccac tgggccaagg aatgcccaca gcccgggatt cctcgtaagc 2400 catgacccat ctgtgtggga ccccactgaa aattggactg ttcaactcac ctggcagcca 2460 tttccagaga ccctggaact ctggcccaag gctctctgac tccttcccca atcttctcag 2520 cttagtggct gaagactgac actgcccgat cgcctcagaa gccccctaaa ccatcacgga 2580 tgctgagctt caggtaactc tcacaatgga aggtaagtcc gtcccattct taatcaatac 2640 ggacgctacc cactccacat taccttcttt tcaagggcct gtttcccttg cctccataac 2700 tgttgtaggt attgatggcc aggcttctaa acctcttaaa actccccaac tctggtgcta 2760 acttagacaa tactctttta agcactcctt tttagttaac cccacctgtt cagttccctt 2820 attaggctga gacactttaa ctaaattatc tgcttccctg actattcctg ggctacagcc 2880 acacctcatt gccatctttt cccccagttc aaagcctcct tcacatcctc cccttgtatc 2940 tccccacctt aacccacaag tataagacac ctctactccc tccttagtga ccgatcatgc 3000 accccttacc atcccattaa aacctaatca cccttaccct gctcaatgcc aatatcccat 3060 cccacagcat gctttaaaag gattaaagtc tgttatcact cacctgctac agcatggcct 3120 tttaaagcct ataacctccc cttacaattc ccccatttta cctgtcctaa aaccagacaa 3180 ggcttacagg ttagttcagg atctgcgcct tatcaaccaa attgttttgc ctatccacac 3240 tgtggtgcca aacctatata ctctcctatc ctcaataccc attattaata ccctcaatac 3300 cctccacaac ccattattct gttccagatc tcaaacttgc tttctttact attcctttgc 3360 acccttcatc ccagcctctc ttccctttca cttggactga ccctgacacc catcaggctc 3420 agcaaattac ctgggctgta ctgctgcaag gcttcacaga cagcccccat tacttcagtc 3480 aagcccaaat ttcttcctta tctgttacct atgatggcat aattctcata aaaacacacg 3540 tgctctccct gctggtcatg tctgactgat ctctcaaacc ccagcacctt ctacaaaaca 3600 actcctttcc ttcccaggca tggttagata ctttcaactt tagatacctg gttttcccat 3660 tataacaaaa ccattatata aactcacaaa aggaaaccta gctgactcca tagatcctaa 3720 atcctttccc cactcctctt tccattcctt gaagacaact ttagagactg cccccactct 3780 agctctccct gactcatccc aacccttttc attacccaca gctgaagtgc agggctgtgc 3840 agtcagaatt cttacacaag gaccaggatc gcatcctgta gcctttttat ccaaacaact 3900 tgaccttact gttttgtcta gccctcaagt ctgcgtgcag cagctaccac caccctaata 3960 cttttagagg cccttaaaat cacaaactat gctcaactca ctctctacag ttctcttaac 4020 ttccaaaacc tattttcttc ctcacacctg acacgtatac tttctgctcc ctggctcctt 4080 cagctgtact cactctttgt tgagtctccc acaattacca ttgttcctgg cctggacttc 4140 aatccggcct cccacattat tcctgatacc acacctgacc gccatgactg tatctctctg 4200 atccacctga cattcacccc atttccccat atttccttct ttcctgttcc tcaccctgat 4260 cacagttggt ttattgatgg cagttccacc aggcctaatt gccacacacc agcaaaggca 4320 ggctatgcta tagcacaagc cactagccaa cctctaagaa cctctcattt cttttccatc 4380 gtggaaatct atcctcaaag aaataacttc tcagtgttcc atctgctatt ctactactcc 4440 tcagggattg ctcaggcctc ccttcctttc cctacacatc aagctcaggg atttgcccct 4500 gcccaggact ggcaaattag ctttactcaa catgccccaa gtcaggaaac taaaatacct 4560 cttggtcagg gtagacactt tcactggata ggtagaggcc tttcccacag ggtctaagaa 4620 ggccaccaca gtcatttctt cccttctgtc agacataatt cctcagtttg gccttcccac 4680 ctctatacag tcctataaca gaccagcctt tattagtcaa atcacccaag cagtttttca 4740 ggctcttagt attcagtgaa acctttatgt cctttacagt cctcaatctt caggaaaggt 4800 agaacggact aatggtcttt taaaaacaca cctcaccaag ctcagccacc aacttaaaaa 4860 ggactggact ggccgggcac cgtggctcat gcctgtaatc ccagtacttt gggaggctga 4920 ggcaggcaga tcacgaggtc aggagatcga gaccattctg gctaacacgg tgaaaacctg 4980 tctctactaa aaatacaaaa aattagccag gtgtggtggc aggtgcctgt agtcccagct 5040 actccggagg ctgaggcagg agaatggcat gaacccagga ggcggagctt gcagtgagcc 5100 aagatcgtgc cactgcactc cagacagagt gcagtgcaag actccatctc aacaaaaaaa 5160 aaaaaggact ggacaatact tttaccactt tcccttcgca gaattcaggc ctgtcctcag 5220 aatgctatag gttacagccc atttgagctc ctgtatagac actccttttt attaggtccc 5280 agtctcattc cagacaccag cccaacttga actgcacccc aaaaacttgg atagagccta 5340 aaaattcacc aaccaagcaa gtaattacgc tgaaccccct tgggcactct ctaattagat 5400 gtcctgggtc ctcccaattc ttagtctaat atctgttttt ctccttctct tattccattt 5460 agtttttcaa ttcacacaaa acagtatcca ggccatcacc aataattcta tacaacaaat 5520 gtttcttcta acaaccccat aatatcgccc cttaccataa aatcttcctt cagcttaatc 5580 tctcccactc taggttccca cgccgcccct aatcccgctc gaagcagccc tgagaaacat 5640 cgcccattat caatccatgc caccccccaa aaaaattttc tccccacccc aacacttcaa 5700 cactattatg ttttattttt cttattaata caagaagaga ggaatgtcag gcctctgagc 5760 ccaagctaag ccatcacatc ccctgtgacc tgcacatcta catccagatg gcctgaagta 5820 actgaagaat cacaaaagaa gtgatattta aatggcctgt tcctgcctta actgatgaca 5880 ttccaccaca aaagaagtga aaatggctgg tccttgcctt aactgatgac attaccttgt 5940 gaaattcctt ctcctggctc atcctggcct aaaaagctcc ctgactgagc accttgtgac 6000 cccccactcc tgcctgccag agaacaaccc ccttttttcc tttacctacc caaatcttat 6060 aaaatggccc cacccctatc tcccttcgct gactctcttt ttggactcag cccgcctgca 6120 cccaggtgat taaaagcttt attgctcaca caaagcctgt ttggtggtct cttcacacag 6180 a 6181 <210> 141 <211> 812 <212> DNA <213> Homo sapiens <400> 141 gtggggaaaa gcaagagaga tcagattgtt actgtgtctg tgtagaaaga agtagacata 60 ggagactcca ttttgttatg tactaagaaa aattcttctg ccttgagatt ctgttaatct 120 ataaccttac ccccaacccc gtgctctctg aaacatgtgc tgtgtcaact cagagttaaa 180 tggattaagg gcggtgcaag atgtgctttg ttaaacagat gcttgaaggc agcatgctcc 240 ttaagagtca tcaccactcc ctaatctcaa gtacccaggg acacaaaaac tgcggaaggc 300 cgcagggacc tctgcctagg aaagccaggt attgtccaag gtttctcccc atgtgatagt 360 ctgaaatatg gcctcgtggg aagggaaaga cctgaccgtc ccccagcccg acacccgtaa 420 agggtctgtg ctgaggagga ttagtaaaag aggaaggaat gcctcttgca gttgagacaa 480 gaggaaggca tctgtctcct gcccgtccct gggcaatgga atgtctcggt ataaaacccg 540 actgtatgct ccatctactg agatagggaa aaaccgcctt agggctggag gtgggacctg 600 cgggcagcaa tactgctttg taaagcattg agatgtttat gtgtatgcat atctaaaagc 660 acagcactta atcctttaca ttgtctatga tgcaaagacc tttgttcacg tgtttgtctg 720 ctgaccctct ccccacaatt gtcttgtgac cctgactcat ccccacctta ggagaaacac 780 ccacaggtgt gtaggggcaa cccaccccta ca 812 <210> 142 <211> 246 <212> DNA <213> Homo sapiens <400> 142 tacttgggag gtcagcaatg ttaattaccc tctagtggtg tttacttaag acctttgtcc 60 ttaaatctgt actgaataaa tgcctggagc cccagcctgt cagggccaca gctgctgact 120 ctttacagca ccctcctcag tgtctgggag ctgccggtcc cctagcctgc tgtttcatgg 180 gatacctgtg tctgagtgca tttcttcatc cgtcacacgg ccagggtatg gaggttggac 240 ccagca 246 <210> 143 <211> 1023 <212> DNA <213> Homo sapiens <400> 143 ttagagtagg tagttaggcg gacaagagca gggcaggaaa gccccccccc ccaatccagg 60 aatgtcaggt gaccatcaga tgatggtcag gagattgtta aactatctct ctaaaataat 120 cattgaaggc cagttgtggt ggctcatgcc tgtaatccta gcattttggg aggctgaggt 180 gggtggatca ctccttgagg tcaggagttt cagaccagcc aggccaacat ggtgaaaccc 240 tttctctact aaaaataaaa aaaaaaaaaa ttagctgggc atggtggcac actcctgtaa 300 tcccagctac tggggaggct gaggcaagag aatcacttga acccaggagt cagagcttgc 360 agtgagctga gattgcacca ctgcactcta gtctgggtga cagagtgaga ctccgtctca 420 aaaaataatt aattaaataa aataataatt ggtcgcagct ggtgccaggg aaaggcagtc 480 tcccaacaga cagaagacac ttgaggctga tgatcagcag cttcctgaga agatctcagg 540 agttggatga gtgggctcaa gcatgcacac taagaggcaa aatggtggag tttaacttgt 600 atatgacctt cctctaggaa cactagactg gtaagggaaa aacgccttaa atgagcatat 660 gcacaacttc agtaaataca gtgtatgcgg cccgcccaag tgctggcagg ccagtgtgca 720 tgcggacagc ctgccccaag gaaaatcaag agaggagaga tgcaagtcct ggaaccatgc 780 caatgtataa aaccccaagt caggggtcag atggggcact tggatttctc aagtcatcca 840 cttggccctc ttccaagtgt acttcctttc gttcctcctc taaaattttt taataaactt 900 tcattcctgc tctaaaactt cagtcagtct ctcactgtgc catatgcccc ttggccaaat 960 tctttcctcc aaggaggtga gaattgagct tgctgcaaac ccgtatggat tcactgctgc 1020 taa 1023 <210> 144 <211> 87 <212> DNA <213> Homo sapiens <400> 144 aaaaggactt gtatttatag ccagacgacc tactcagtta ctcaatttgt gaccaggaaa 60 taaccaacct tatgtatgtt ataaccc 87 <210> 145 <211> 3585 <212> DNA <213> Homo sapiens <400> 145 gtcaggcctc tgagcccaag ttaagccatc atatcatccc ctgtgacccg catgtacaca 60 tccagatggc cggttcctgc cttaactgat gacattccac cacaaaagaa gtgaaaatgg 120 cctgttcctg ccttaactga tgacattgcc ttgtgaaatt ccttctcctg gctcatcctg 180 gctcaaaagc tcccccactg agtaccttgt gacccccact cctgcccgcc agagaacaac 240 cccctttgac tgtaattttc ctttacctac ccaaatctta taaaacggcc ccacccctat 300 ctcccttggc tgactctctt tttggactca gcccgcctgc acctaggtga aataaacagc 360 tttattgctc acgcaaagcc tgtttggtgg tctcttcaca tggacgcgca tgaaatttgg 420 tgccatgact cagatcgggg gacctccctt gggacatcaa tcccctgtct tcctgctctt 480 tgctccatca gaaagatcca cctatgacct caggtcctca gaccaaccag cccaaggaac 540 atctcaccaa ttttaaatcc agtaagtgac ctcttcttac tctcttctcc aacctctctc 600 actgtccctc aaccactttc tcctttccac tcttcaatct ctcccttctt tcaatttcaa 660 ttcctttcat tttctggtag agataaagga gacacgtttt atccgtggac ccaaaactcc 720 ggcgccagtc acggactggg aaggcagcct tcccttggtg tttaatcatg cagggacgcc 780 tctctgatta ttcacccatg tttcagaggt gtcagaccac gcagggacgc ctgccttggt 840 cctttgccct tagcggcaag tcccgctttt ctggggtagg ggcaggtacc ccaacccctt 900 ctctccgtgt ctctacccct tctccgcctt tctgggggac aagaaacccc caaccccttc 960 tccttcaccc ttagcggcaa gtcccgcttt tctagaggag aggcaagtac cccaacctcg 1020 tatctctgtg ccccaatccc ttatttccat gcaccgacct cttatatctg tgccccaatc 1080 ccttatttcc gtgccccaac ctcttacatc tctgtgcccc gatcccttat ttccgtgccc 1140 caacctctta tatctctgcg ccctgatccc ttatttccac accctgacct cgtatctctg 1200 tgccctgacc cctttcccac ttttctggag ggtaagaacc cccgaaccgc ttccctctgt 1260 gtctctactc tcccttttct ttaaacttgc ctccttcact atgggcaacc ttccaccctc 1320 cattcctcct tcttcgccct tagcctgtgt tcttaagaac ttaaaacctc ttcaactctc 1380 acctgaccta aaatctaagc atcttatttt cttctgcaat gccacttgac cccaaacaaa 1440 ctcgactgca gttccaaata gccagaaaac ggcactttca atttttccat cctgcaagat 1500 ctaaataatt cttgtaaaat gggcaaatgg tctgagatgc ctgacgtcca ggcattcttt 1560 tacacattgg tccctcccta gtctctgtgc ccagtgcaac tcgtcccaaa tcttccttct 1620 ttccctccca cctgtcccct cagtcccaac cccaagcatt gctgagtctt tctaatcttc 1680 cttttctaca gacccatctg acctctcccc tcctccccag actgctcctc accaggccga 1740 gctaggtccc aattcttcct cagcctctgc tcccccaccg tataatcttt ttatcacctc 1800 ccctcctcac acccggtcca gtttacagtt tcattccttg agtagccctc ccccacctgc 1860 ccagcaattt cctcttaaaa aggtggctga agctaaaggc atagtcaagg ttaattcttc 1920 tttttcttta tcccaaatca caagcgttta ggctgttttt aatcaaatat aaaaacccag 1980 cccagttcat gactcctttg gcagcaaccc tgagccactt tacagcccta gaccctaaaa 2040 ggtcaaaagg tgtcttattc tcaatataca ttttattacc caatctgctc ccgacattaa 2100 ataaaactcc aaaaattaaa ttccggccct caaaccccac aacaggattt aattaacctc 2160 gccttcaagg tgtacaataa tagaaaaaag ttgcaattcc ttgcctccac cgtgagacaa 2220 accccagcca catctccagc acacaagaac ttccaaacgc ctgaaccgca gcagccaggc 2280 attcctccag aacctccttc cccaggagct tgctacaagt gccagaaatc tggccactgg 2340 gccaaggaat gcccacagcc caggattcct cctaagtcgt atcccatctg tgtgggaccc 2400 cactgaaaat cagactgttc aactcacctg gcagccactc ccagagcccc tggaactcta 2460 gcccaaggct ctctgactga ctccttccca gatcttcttg gcttagcagc tgaagactga 2520 cactgcccga ttgcctcaga agactacggg accatcacag atgctctaag taactctcag 2580 agtggagggt aagtctttct ccttcttaat caatacggag gctacccagt ccacattacc 2640 ttcttttcaa gggcctgttt ccctcacccc aataactgtt gtgggtattg acggccaagc 2700 ttcaaaatcc ctgaaaactc ccccactctg gtgccaactt ggacaacact cttttaagca 2760 ctctttttta attatcccca cctgcccagt tcccttatta agccaagata ttttaagcaa 2820 attatctgct tccctgacta ttcctggact acagccccat ctcattgccg cccttctccc 2880 caacccaaag cctccttcac atcttcctct catatccccc caccttaacc cacaagtatg 2940 ggacatctct actccttccc tggcaaccga tcacatgccc attaccatcc cattaaaacc 3000 taatcaccct taccccgctc aaccccaata ttccatccca cagcatacct tgaaaggatt 3060 aaagcctgtt atcactcacc tgctagagca tggcctttta aagcctataa actctcctta 3120 tcattccccc attttacctg tcctaaaacc agacaagcct tacaagttag ttcaggatct 3180 atgccttatc aaccaaattg ttttgcctat ccaccccatg gtgccaaagc catatactca 3240 cctatcctca atacctccct ccacaaccca ttattctgtt ctggatctca aacatgcttt 3300 ctttactatt cctttgcacc tgtcatccca gcatctcttc gcttgcactt ggactgaccc 3360 tgacacccat caggctcagc aaattacctg ggctgtactg ccgcaaagct tcacagacag 3420 cccccattac ttcactcaag cccaaatttc ttccttatct gttacctatc tcagcataat 3480 tctcataaaa acacacgtgc tctctctgct gatcgtgtcc gattaatctc ccaaacttca 3540 atcccttaca aaacaacaac tcctttcctt cctagaaatg gttag 3585 <210> 146 <211> 5738 <212> DNA <213> Homo sapiens <400> 146 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac gtacacatcc 60 agatggccgg ttcctgcctt aactgatgac attccaccac aaaagaagtg aaaatggcct 120 gttcctgcct taactgatga cattgtcttg tgaaattcct tctcccggct catcccggct 180 cagaagatcc cctactgagc accttgtgac cccccactcc tgcccgccag agaacaaccc 240 ccctttgact gtaattttcc tttacctacc caaatcttat aaaacggccc caccccatct 300 ctcttcactg actctttttg gactcagccc gcctgcaccc aggtgattaa aagctttatt 360 gctcacataa agcctgtttg gtggtctctt cacacagacg tgcatgaaat ttggtgccat 420 gactcgcatt gggggacctc ccttgggaga tcaatcccct gttctccggc tctttgctcc 480 ctgagaaaga tccacctacg gcctcaggtc ctcagaccaa ccagcccaag aaacatctca 540 ccaatttcaa atcaggtaag cggcctcttc ttattccctt ctccaacgtc tctcactatc 600 cctcaaccac tttctccttt ccactcttca atctctccct tctcttaatt tcaatttctt 660 tcattttctg gtagagataa aggagacaca ttttatccgt ggatccaaaa ctccggcgcc 720 agtcacggac tgggaaggca gccttccctt ggtgtttaat cattgcaggg atgcctctct 780 gatcattcac ccaagtttca gaggtgtcag atcacacagg gatgcctgcc ttggtccttc 840 acccttagcg gcaagtcccg cttttctggg ggaagcgaaa gtaccccaac cctttctctc 900 catgtctcta ccccttctcc acctttctgg ggggcaagaa acccccaacc ccttcttcac 960 ccttagcagc aagtcccgct tttctggagg aggggccagt accccaacct catatatctg 1020 tgccccaacc tcttatatct ctgcgcccca atcccttatt tccatgcgcc aacctcttat 1080 atctctgcgc cccgatccct tatttccaca ccccaacctc ttatatctct gtgccccaat 1140 cccttatttc tgtgccctga cctcatatct ctgtgcccca accccttctc tgcttttctg 1200 gagggcaaga accccccacc ccttctccgt gtctctactc ttttctctcg gcttgcctcc 1260 ttcactatgg gcaagcttcc atcttccatt tctccttctt ctcccttagc ctgtgttctt 1320 aagaacttaa aacctcttca actctcacct gacctaaaat ctaagagtct tattttcttc 1380 tgcaatgccg cttgacccca atacgaactc gacagtagtt ccaaatagcc agaaaatggc 1440 actttcaact tttccatcct acaagatcta aataattctt gtcataaaat gggcaaatgg 1500 tctacggtgc ctgatgtcca ggcattcctt tacatatcag tccctctcta gtctctgttc 1560 ccagtgcaac tcatcccaaa tcttccttct ttccctccca cctgtcccct cagtcccaac 1620 cccaagcgtc actgagtctt tctaatcttc ctttctacag attaggggtc agacacatct 1680 gacctctccc ctcctcccca ggctgctcct cgccaggcca agctaggtcc caattcttcc 1740 tcagcctccg cttctccacc ctataatcct tttatcccct cccctcctca cacctggtct 1800 ggcttacagt ttcgttccat gactagccct cccccacctg cccagcaatt tactcttaaa 1860 aaggtggctg gagctaaagg catagtcaag gttaatgttc ctttttcttt atcccaaatc 1920 agatagcatt taggctcttt ttcatcaaat ataaaaatcc agcccagttc atgacttgtt 1980 tggcaacaac cctgagacac tttacagtcc tagaccctaa aaggtcaaaa ggccatctta 2040 ttctcaaaat acattaccca atctgctcct gacattaaat aaaactccaa aaattaaatt 2100 ccggccctca aaccccacaa caggatttag ttaacctcag cttcaaggtg tacaataata 2160 gaaacaagtt gcaattcctt gtctccactg tgagacaaac cccagccata tctccagcac 2220 acaagaactt ccaaaggcct gaaccgcagc ggccaggcgt ggcattcctc cagaacctcc 2280 tcccccagga gcttgctaca agtgccagaa atctggccac caggccaagg aatgcccgca 2340 gcccgggatt cctcctaagc tgcatcccat ctgtgtggga ccccactgga aatcggactg 2400 tccaactcac ctggcagcca cgccactccc agagcccctg gaactctggc ccaaggctct 2460 cagactcctt cccagatctt cttggcttag cggctgaaga ttgacgctgc tcaagcgcct 2520 cggaagcccc ctagaccatc acggatgccg agcttcaggt aactctcaca gtggaaggta 2580 agtccgtccc cttcttaatc aatatggagg ctacccactc cacattacct tcttttcaag 2640 ggcctgtttc ccttgcctcc ataactgttg tgggtattaa cagccaggct tctaaacctc 2700 ttaaaactcc ccaactctgg tgccaattta gacaatactc ttttgagcac tccttttagt 2760 tatccccacc tgcccagttc ctttattagg ccgagacact ttaactaaat tatctgcttc 2820 cctgactatt cctggattac agctatatct cattgctgcc cttcttccca atccaaagcc 2880 tcctttgcat cctcctcttg tattccccca ccttaaccca caacaataag atacctctac 2940 tccctccttg gtgaccaatc atgcacccct taccatctca ttaaaaccta atcaccctta 3000 ccctgctcaa tgccaatatc ccatcccaca gcatgctttg aaaggattaa agcctgttat 3060 cactcacctg ctatagcatg gccttttaaa gcctataaac tctccttaca attcccccat 3120 tttacctgtc ctaaaaccag acaagcctta caagttagtt caggatctat gccttatcaa 3180 ccaaattgtt ttgcctatcc accccatggt gccaaaccca tatactctcc tatcctcaat 3240 acctccctcc acaatccatt attctgttct ggatctcaaa catgctttct ttactattcc 3300 tttgcaccca tcatcccagc ctctcttcgt tttcacttgg actgaccctg acacccatca 3360 ggctcagcaa attacctggg ctgtactgcc gcaaggcttc acagacagcc cccattactt 3420 cagtcaagcc caaatttcat cctcatctgt tacctatctt ggcataattc tcataaaaac 3480 acacgtgctt tccctgctga tcatgtctga ttaatctccc aaacctcaat cccttacaaa 3540 acaacaactc ctttccttcc taggcatggt tagtgtggtc agaaatctta cacaagagcc 3600 aggaccgcac cctgtagcct ttctgtgcaa acaacttgac cttactgttt tagcctagcc 3660 ctcatgtctg cctgcagcgg ctgctgctgt tttaatactt ttagaggccc taaaaatcac 3720 aaactatgct caactcactc tctacatttc tcataacttc caaaatctat tttcttcctc 3780 atacctgacg catatacttt ctgctccccg gctccttcag ctgtactcac tctttattaa 3840 gtcccacaat taccattgtt cctggcccgg acttcaatct ggcctcccac attattcctg 3900 ataccacacc tgacccccat gactgtatct ctctgatcca cctgatattc accccatttc 3960 cacatatttc cttctttcct gttcctcacc ctgatcacgc tttatttatt gatggcagtt 4020 ccaccaggcc taatcgccac acaccagcaa aggcaggcta tgctatagta caagtcacta 4080 gcccgcctct tagaacctct catttccttt ccaccgtaga aatctatcct caaggaaata 4140 acttctcagt gttccatctg ctattctact actcctcagg gattattcag gccccctccc 4200 ttccctacac atcaagctca aggatttgcc cccatccagg actggcaaat tagctttact 4260 caacatgccc cgagtcagat aactaaaata cctcttagtc taggtagaca ctttcactgg 4320 ataggtacag gcctttccta cagggtctga gaaggccacc acagtcattt cttcccttct 4380 gtcagacata attcctcagt ttagccttcc cacctctata cagtctgata acagaccagc 4440 ctttattagt caaatcagcc aagcagtttt tcaggctctt agtattcagt gaaaccttta 4500 tattccttat ggtcctccgt cttcaggaaa agtagaacgg actaaaggtc ttttaaaaac 4560 acaccttccc aagctcagcc accaacttaa aaaggactgg acaatacttt taccactttc 4620 ccttctcaga agtcagacct gtcctcagaa tgctacaagg tactgcccat ttgagctcct 4680 gtatagacat tcctttttat taggccccag tctcattcca gacgccagac caacttagac 4740 tgtgccccaa aaaaacttgt catccctact aacttctgtc tagtcatact cctattcacc 4800 attctcaact actcatacat gccctgctct tgtttacact gccggtttac gctgtttctc 4860 caagccatca cagctgatat ctcctggtgc tatccccaaa ctgccactct taactcctga 4920 agtaaataaa taatctttgc tggcaggact atgctgaatc tccttaggca ctctctaatc 4980 agatgtcctg ggtcatccca attcttagac cttttatacc tgtttttctc cttctgttat 5040 tccatttagt ttttcaattc atacaaaact gtatccaggc cattaccaat aattctacat 5100 gacaaatgtt tcttctaaca accccacaat gtcacccctt accacaaaat cttccttcag 5160 cttaatctct cccactctag gttcccacac cacccctaat cccgctcgaa gcagccctaa 5220 gaaacatcgc ccactatctc tccatactat cccccaaaat tttcactatc ccaacacttt 5280 accactattt cgttttattt ttcttattaa tataagaaga caggaatgtc aggcctctga 5340 gcccaagcta agccatcata tcccctgtga cctgcacgta cacaaccaga tggccggttc 5400 ctgccttaac tgatgacatt ccaccacaaa agaaatgaaa atggcctgtt cctgccttaa 5460 ctgataacat tgtcttgtga aattccttct cccggctcat cctggctcaa aagctcccct 5520 actgagcacc ttgtgacccc cactcctgcc cgccagagaa caacccccct ttgactgtaa 5580 ttttccttta cctactcaaa tcttataaaa cggccacacc cctatctctc ttcactgact 5640 ctcttttcgg actcagcctg cctgcaccca ggtgattaaa agctttattg ctcacacaaa 5700 gcctgtttgg tggtctcttc acacggatgc ccatgaaa 5738 <210> 147 <211> 429 <212> DNA <213> Homo sapiens <400> 147 gtcaggcctc tgagcccaag ctaagccatc gtatcccctg tgacctgcac gtatatgtcc 60 acatggcctg aagcaagtaa agaatcacaa aagaagtgaa aatggccggt tcctgccttc 120 actgatgaca ttccaccact gtgatttgtt cctgccccac cttaactgag caattaacct 180 tgttaaattc cttctcctgg ctcagaagct cccccactga gcaccttgtg acccgcccct 240 gcccgtaaga gaaaaacccc ctttgattgt aattttccac tacccaccca aatcctataa 300 aacagcccca ccctaggtcc cttcgctgac tctcttttcg gactcagccc acctgcaccc 360 aggtgaaata aacagccttg ttgctcacac aaagcctgtt tggtggtctc ttcacatgga 420 cgcgcgtga 429 <210> 148 <211> 6120 <212> DNA <213> Homo sapiens <400> 148 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac gtattcgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa tatgccctgc cccaccttaa 120 ctgatgacat tccaccacaa aagaagtgta aatggccggt ccttgcctta agtgatgaca 180 ttaccttgtg aaagtccttt tcctggctca tcctggctca aaaagcaccc ccactgagca 240 ccttgcgacc cccactccgg cccaccagag aacaaacccc ctttgactgt aattttcctt 300 tacctacaca aatcctataa aatgacccca tccttatctc ctttcgctga ctgtcttttc 360 agactcagcc cacctacacc caggtgaaat aaacagccat gttgctcaca caaagcctgt 420 ttggtggtct cttcacacgg atgcacatga aatttggtgc catgactcag atcgggggac 480 ctcccttagg agatcaatcc cctggcctcc tgttctttgc tccatgagaa agatccacct 540 acgacctcag gtcctcagac tgaccagccc aagaaacatc tcaccaattt caaatccagt 600 aagcggcctc tttttactct cttctccaac ctccctcact atccctcaac ctctttctcc 660 tttcaatctt ggcaccactc ttcaatctct ccgttctctt aatttcaatt cctttcattt 720 tctaggagag acaaaggaga cacgttttat ccgtggaccc aaaactccgg cgccggtcac 780 ggactgggaa ggcagccttc ccttggtgtt taatcattgc agggacacct ctctgattat 840 tcacccatgt ttcaaaggtg tcagaccatg gagggatgcc tgccttggtc cttcaccctt 900 agcggcaagt ccagcttttc taggaaaggg gcaagtaccc caaccccttc tttccttgtc 960 tctacccctt ctctgctttt ctgggggagg ggcaagtacc cctcaacccc ttctccttca 1020 cccttagcgg caagtcccgc ttttctgggg gaggggcaag tacccctcaa ccccttctcc 1080 ttcactctta gtggcaagtc ccgctcttct agagcagggg caagtacccc aacctcatat 1140 ctctgtgccc cagtccctta tttccacgcc ccaacctctt atatctctgc accccaatcc 1200 cttatttcca tgccccaacc tcttatctct gtgccccaat cccttatttc catgccccga 1260 ccccttattt ctgtgcccca tcccttattt ctgtgcccca acctcttatc tctgtgcccc 1320 aacccctttt cccacttttc tggaaggtaa gaacccccga accccttccc tccgtttctc 1380 tactctcttt tctctaggct tgcttccttc actatgggca actttccacc ctccattcct 1440 ccttctactc ccttggcctg tgttctcaaa aacttaaaac ctcttcaact cacacctgac 1500 ctaaaaccta aatgccttat tttcttctgc aatgctgctt gactccaata caaactcgag 1560 agtagttcca catagccaga aaatggcact ttgaattttt ccatcctgca aaatctaaat 1620 aattattgtc gtaaaatagg caaacggtct gaggtgcctg aagtccaggc attcttttac 1680 acatcagtcc cttcctagtc tctgtgccca gtgcaactca tcccaaatgt tccttctttc 1740 cctcccatct gtcccctcag taccaacccc aagcgtcact gagtctttct aatcttcctt 1800 ttgtacagac ccatctgacc tctcccttcc tccccaggct gctcctcgcc aggccgagct 1860 aggtcccaat tcttcctcag cctccgttcc tccacgctgt aatcttttta tcacctcccc 1920 tcctcacacc tggtccggct tacagtttcg ttctgtgact agccctcccc cacctgccca 1980 gcaatttact cttaaaaagg cggctggagc caaaggcata gtcagggtta atgctcctct 2040 ttctttatcc caaatcagaa gcgtttaggc tctttttcat caaatataaa aatccagccc 2100 agttcatggc tcgtttggca gcaaccctga gccactttac agccctagac cctaaaaggt 2160 caaaaggccg tcttattctc aaaatacatt ttattaccca atctgctcct gacattaaat 2220 aaaactccaa aaattaaatt ctggccctca aaccccacaa caggatttaa ttaacctcgc 2280 cttcaaggtg tacaataata gaaaaaattt gcaattcctt gccttcactg tgagacaaac 2340 cccagccaca tctccagcac acaagaactt ccaaacgcct gaaacgcagt ggccaggcat 2400 tcctccagaa cctcctccca cagagcttgc tacacgtgct ggaaatctgg acactgggcc 2460 aaggaatgcc cacagcctgg gattcctcct aagccgtgtc ccatctgtgc gggaccccac 2520 tggaaatcgg actgttcaac tcacctggca gccactccca gagcccctgg aactctggcc 2580 caaggctctc tgactgactc cttcccagat cttctcagct tagcagctga agactgacac 2640 tgcctaatct cctcggaagc cccctagacc atcatggacg ccgagcttca ggtaactctc 2700 acagtggaag gtaagcccat ccccttctta atcaatatgg agggtaccca ctccacatta 2760 cctccttttc aaaggcctgt ttcccctgcc tccgtaactg ttgtgggtat tgatggctag 2820 gcttctaaac ctcttaaaac tccccaactc tggtgccaac ttagacaata ctcttttaag 2880 cactcctttt tagttacccc cacctgccca gttcccttat taggctgaga cactttaact 2940 aaattatctg cttccctgac tattcctgga ctacagctat atctcattgc cacccttctt 3000 cccaatccaa agcctccttt gtgtcctcct cttgtatccc ccgaccttaa cccacaagta 3060 taagatacct ctactccctc cttggtgacc aatcatgcac cccttaccat ttcattaaaa 3120 cctaatcacc cttaccccac tcaacgccaa tatcccatcc cgcagcacgc tttaaaaaga 3180 ttaaagcctg ttatcactca cctgctacag catggccttt taaagcctat aaactctcct 3240 tacaattccc ccattttacc tgtcctaaaa ccagacaagc cttacaagtt agttcaggat 3300 ctgcgcctta tcaaccaaat tgttttgcct atccaccccg tggtgccaaa cccatatact 3360 ctcctatcct caatacctgc ctctacaacc cattattctg ttctagatct caaacatgct 3420 ttcttcacta ttcctttgca cccttaatca cagcctctct tcgctttcac ttggactgac 3480 cctgacaccc atcaagctca gcaaattacc taggctgtac tgccacaaag cttcacagac 3540 agcccccatt acttcaatca agcccaaatt tcttcctcat ctgttaccta tctcagcata 3600 attctcataa aagcacacat gctctccctg ccaatcgtgt ctgactgatc tctcaaaccc 3660 caaccccttc tacaaaacaa ctcctttcat tcctgggcat ggttggatac tttcgccttt 3720 ggatacctgg ttttgccatc ctaacaaaac cattatataa actcacaaaa gaaaacctag 3780 ctgatcccat agatcctaaa tccttttccc actcctcttt ctgttccttg aagacagctt 3840 tagaaactgc ccccactcta gctctccctg actcatccca acccttttca ttacacacag 3900 ccgaagtgca gggctgtgca gtcagaattc ttacataagg accaggatcg catcctgtag 3960 cctttttgtc caaacaactt gaccttacag ttttaggctg gccatcatgt ctccgtgcag 4020 ctgctgctgc ttccctaata cttttggagg ccctcaaaat cacaaactat gctcaactca 4080 ctctctacag ttctcaactt ccaaaatcta ttttcttcct catacctgat gcatatactt 4140 tctgctccct ggctccttca gctgtactca ctctttgttg agtctcccac aattaccgtt 4200 gttcctggcc cagacttcaa tctggcctcc cacattattc ctgataccac acccgacccc 4260 catgactgca tctctctgat ccacctgaca ttcaccccat ttccccaaat ttccttcttt 4320 cctgttcctc accctgatca cacttgattt attgatggtg gttccaccag gcctaatcgc 4380 cacacgccag caaaggtagg ctatgctata gtacaagcca ctagcctgcc tcttagaacc 4440 tctcatttcc tttccattgt ggaaatctat cctcaaggta ataacttctc agtgttccat 4500 ctgctgttct actactcctc agggattatt caggccccct cccttcccta cacatcaagc 4560 tcgaggattt gccccaccca ggactggcaa attagcttta ttcaacatgc cctgagtcag 4620 ataactaaaa tacctcttag tctaggtaga tactttcact ggataggtag aggcctctcc 4680 tacagggtct gagaaggcca ccgcagtcat ttcttccctt ctgtcagaca taattcctca 4740 gtttagcctt cccacctcaa tacagtctga taacagatga gcctttatta gtcaaatcag 4800 ccaagcagtt tttcaggctc ttagtgttca gtgaaacctt tatgtccctt acggtcctcc 4860 gtcttcaaga aaggtagaat gaactaaagg tcttttaaga acacacctca ccaagctcag 4920 ccaccaactt aaaaaggact ggacaatact tttatcactt tcccttctca gaattcaggc 4980 ctgtcctcgg aatgctacag ggtacaaccc atttaagctc ctgtatagac gctccttttt 5040 attaggcccc agtctcattc cagacaccag accaacttag actgtgcccc aaaaaacctg 5100 tcatccctac tatcttctgt ctagtcatac tcctatttac cattctcaac tactcataca 5160 ggccctgctc ctgtttacac tgctggttta cactgttttt ccaagccatc acagctgata 5220 tctcctggtg ctatccccag actgccactc ttaactcttg aagtaaataa ataatctttt 5280 ctggcaggac tatgctgaat ctccttaagc actctctaat cagatatcct gagtagtccc 5340 aattcttaga ccttttatac ctgtttttct ccttctgtta ttccatttag tttctcaatt 5400 catccaaaac cgtatccagg ccatcaccaa tcattctata cgacaaatgt ttcttctaac 5460 atccccacaa tatcacccct taccacaaga cctcccttca gcttaatctc tcccactcta 5520 ggctcccacg ccgcccctaa tcccgcttga agcagccctg agaaacatcg cccattctct 5580 ctccatacca tcccccaaaa atttttgcca caccaacact tcaacactat ttcattttat 5640 ttttcttatt aatataagaa gtcaggaatg tcaggcctct gagcccaagc caagccatcg 5700 catcccctgt gacttgcacg tatataccca gatggcctga agtaactgaa gaatcacaaa 5760 agaagtgaat atgccctgcc ccaccttaac tgatgacatt ccaccacaaa aaaagtataa 5820 atggtcggtc cttgccttaa gtgatggcat taccttgtga aagtcctttt cctggctcat 5880 cctggctcaa aaacaccccc actgagcacc ttgcgacccc cactcctgcc cgccagagaa 5940 caaaccccct ttgactgtga ttttccttta cctactcaaa tcctataaaa gggccccacc 6000 cttatctccc ttcgctgact ctcttttcag actcagcccg cctgcaccca ggtgaaataa 6060 acagacatgt tgctcacaca aagcctgttt ggtgggcttt tcacacggac gcgcatgaaa 6120 <210> 149 <211> 2754 <212> DNA <213> Homo sapiens <400> 149 tggatcaggt gcaaagtaag cccaccccac tgagaactat gttaaagaat ttcaagaaag 60 gatttaatgg agactatgga gtcactatga ctccaggaaa acttagagct ttgtgtgaaa 120 tagactggcc agcattagag gtaggttgga catcagaagg aagcctggac aggtcccttg 180 tttcaaaggt atgacacaaa gtaacctgta aaccaaggca ccaagaccag tttccataca 240 tagacagtta cagctgtctt tagacccctt cccccccaac agtagttaag agaacagcag 300 cataagcagc tggcagaggc aaggaaagac cagcagagag aaaaaaaagg ccatctatac 360 caattctaag ttaatttaga ctaaacaagg tcttattaat agcaaaggat aattgaaatc 420 ccaaacttac aaggttttca acaaaagtga agtttgctaa aagttaacag tgtaacacat 480 attatggtaa attctaatct tgtggcctta gacagtctag tccaaagaca tcaaaaaagt 540 ttgcttaaaa aaaaagaaat ggttatcttc aaaaaaaaaa aaaaaaaaaa aaagaagggg 600 aggcaaaatt tacgtaaaaa gagtgttata tggtaaattc ttgttctgaa ataaattggt 660 tgtttcaaga aaaaaatgtt tgtaataagt caaaaagttg agacatgttg aagaattgtc 720 agtggaagtc gtgaaaaaaa gttataaaaa tttatgcaaa aaggttttat aatttaaaag 780 taatttggcc tcttgagtac tattgaagaa acagtttatg tgcaaagtgt ataaaaaagt 840 aaaacatacc tttggtaaaa agattataag gaggcataaa aatgtggatt tttacctaca 900 ttaaaaggtt aaaaaaatta ttgttttaaa agtttaagca agttttaaaa cattaattgt 960 aaagaaaagt ctgtgtgtaa acatattagc taaagttaaa aagatatcat ccagtttttc 1020 tgcgaactag acataaaagt aaaaatgcaa caggtttttt ttcttaaagc atcaacctgc 1080 tctttaacaa aaattataaa aggttaaaaa gagtctataa aatcttacct tatggtcaaa 1140 catgaaaaat tagataaata tgtcttcaag gttttattaa aattaagttt aatattaata 1200 gcatactaat ataaaggtaa aatttagctt atctggtata aaaatcatac aagaagcatt 1260 attaaatatg aaatggtgtt tagctttctt tggtctaaaa actaatacaa attggtgcta 1320 aaggaaacat tcattttact agaagatcac agaagttaaa gacttaaaaa aaactttggc 1380 aattaagaca gcataccaag atgcaaatgc ctggttgaaa tagatcaaat attccatctg 1440 cacgttaaac aaaagcaatt gttatgcttg tgcacatggc aggccagagg ccctaattgt 1500 cccctttcca ctacagtggt cctccagttg accaggcgta ggctgcatgg taactctttt 1560 ccaggattct acagcctgga gtaataagtc atgccaagct ctctctgcta tatcctgaag 1620 tccctgtggg tcagcctccg agggccatcc agcttccatc tcccaacact aagttcactt 1680 cgtgtctctc acagcaggga ggagacagca ttccttagag acctgaaagg atgcagtgag 1740 cttaagaatt ttcgaaaggt tatcaatcag tcagccgttg ttcatccccg agcagatgtg 1800 tggtggtatt gtggtggacc tttactaggt actctgctga ataagtagag tggcacttgt 1860 gctttagtcc atttggctat ccctttcatc ctggcatttc atcaaccaga ggaagaaaag 1920 aaaataataa gatatcataa agcgagagaa gccccttata ggtcttccaa ctctcatatc 1980 tatttagatg caattagagc cccgcaagga ataccagatc aatttaaagc ttgaaatcaa 2040 atagctacag gatttaagtc aatattttgg tagatgacag tgaataaaaa tgtagattag 2100 ataaactaca tctattacaa ccaacagcaa agagcttttc atgagttaaa aaaaaaaaaa 2160 ctcatgtcgg ccccagccct gaggttacct gacctgactc tgtgaagtct gtgtgtcaga 2220 aaagaaaaaa atggcagttg gagttttaac tcagactgtg gggcactggc caaggccagt 2280 ggcctatctc tcaaaacaaa aagacagggt ttccaaaggc tggcccccat gtccaagggc 2340 cctggcagca atggccctgt taccacaaga agcagataag ctaactctta gacaaaacct 2400 aaacataaag tctccccatg ctgtggtgat tttaataaat actaaaggac accattagct 2460 aataaatgtt acactaagta gataccaaag cttgctctgt gaaaatcccc acataaccat 2520 tgaagtttgc aacaccctaa ccctgccacc ttactcctgg tatcagagag cctagttaaa 2580 cataactgtt tagaggtgct ggactcagtt tattctagta ggcccaacct ccgagacaat 2640 ccttaaccat cagtagacta ggagttgtat gtagatagga gcagcgtcac caacccctgc 2700 aaagtgactc tgaagaagac tacaagccct gctccagtca cacccagaag ctga 2754 <210> 150 <211> 71 <212> DNA <213> Homo sapiens <400> 150 tggctgactc ttttcggact cagcccgcct gcgcacccag gtgaaataaa cagccatgtt 60 gctcacaaaa a 71 <210> 151 <211> 497 <212> DNA <213> Homo sapiens <400> 151 atggaatgag accaccactt ctcctgttgt ccttcccagc ttctccccta cctcctcttt 60 tccctagttt ataagacagg agaaaaggga gaaagcaaaa agttggaaag aaacagaagt 120 aagataaata gctagatgac cttggcgcca ccatctggcc ctggtggtta aaataataat 180 aataatatta acccctgatc aaaattactt gtgttatctg taaattccag acattgtatg 240 agaaagcact gtaaaacttt ttgttctgtt aggtgatgca tgtagccccc agtcacgttc 300 ctcatgcttg cttgatctat tatgaccctt tcacgtggat cccttagagt tgtaagccct 360 taaaagggct aggaatttct ttttcggaga gctcagctct taagatgaga ctctgccaac 420 tcttccagcc gaataaaaac ctcttccttc tttaatctgg tgtctgagga gttttgtctg 480 gggcttgtcc ggctaca 497 <210> 152 <211> 4053 <212> DNA <213> Homo sapiens <400> 152 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacatgcgc gtatacatcc 60 agatggcctg gagtaactga agatccacaa aagaagtgaa aatagcctta actgatgaca 120 ttccactatt gtgatttgtt cctgccccac cataactgat caatgtactt tgtaatctcc 180 cccaccctta agaaggttct ttgtaattct ccccaccctt gagaatgtac tttgtgagat 240 ccacccctgc ccacaaaaca ttgctcttaa cttcaccgcc tatcccaaaa cctgtaagaa 300 ctaatgataa tccatctccc ttcgctgact ctcttttcgg actcagcccg cctgcaccca 360 ggtgaaataa acagccatgt tgctcacaca aagcctgttt ggtggtctct tcacacggac 420 gtgcatgaaa tttggtacca tgactcggtt cggaggacct cccttgggag atcaatcccc 480 tgtcctcctt gctctttgct gcatgagaaa gatccatcta tgtatgacct caggtcctca 540 gatggaccag cccaagaaac atctcaccaa tttcaaatcc agtaagtagc ctctttttac 600 tctcttctcc aaattccctc actatccctc aacctctttc tcctttcaat cttggtgcca 660 cacttcaatc tctcccttct cttaatttca attcctttca ttttctggta gagacaaagg 720 agacacgttt tatccgtgga cccaaaactc cggcaccggt cacggactgg gaaggcagcc 780 ttcccttggt gtttaatcat tgcagggaca tctctctgat tattcaccca cgtttcaaag 840 gtgtcagacc acgcagggac gcctgccttg gtccttcacc cttagcggca agtcccgctt 900 ttctggggga ggggcaagta ccccaacccc ttctctctgt gtctctaccc cttctctggt 960 tttctggggg aggggcacat accccaaccc cttctcttca tgtctctacc ccttctctgg 1020 ttttctgggg gaggggcaag taccccaaac ccttctctcc gtgtctctac cccttctctg 1080 ctcttctggg gcaggggcaa gaacccctca accccttctc cttcaccctt agtggcaagt 1140 cccgcttttc tagagggcaa gaacccccaa tcccttattt ccgtgcccca acaccttctc 1200 tgcttttctg gagggcaaga accccctacc ccttctccgt gtctctactc ttttctctgg 1260 gcttgcctcc ttcactatgg gcaagcttcc accttccatt cctcctcctt ctcccttagc 1320 ctgtgttctt aagaacttaa aacctcttca actctcacct gacctaaaat ctaagcatct 1380 tattttcttc tgcaatgccg cttgacccca atacaaactc gacagtagtt ccaaatagcc 1440 agaaaacggc actttcaatt tttccatcct acaagatcta aataattctt gtcataaaat 1500 gggcaaatgg tctgagatgc ctgacatcca ggcattcttt tacacatcag tcccttccta 1560 gtctctgtgc ccaatgcaac tcatcccaaa tcttccttct ttccctcttg cctgtcccct 1620 cagtcccaac gtcaagcgtc actgcgtctt tctaatcttc cttttctaca gacccatctg 1680 acctctcccc tcctccccag gctgctcctc gccaggccaa gctaggtccc aattcttctt 1740 cagcttctgc tcctccactc tataatccat ttatcacctc ccctcctcac acctggtccg 1800 gcttatggtt tcattctgtg actagccctc ccccacctgc ccagcaattt actcttaaaa 1860 aggtggctgg agctaaaggc atagtcaagg ttaatgctcc tttttcttta tcccaaatca 1920 ggtagccttt aggctctttt tcatcaaata taaaaaccca gcccagttca tggctcgttt 1980 ggcagcaacc ctgagaagct ttacagccct agaccctaaa aggtcaaagg gccgtcttat 2040 tcttaatata cattttatta cccaatctgc tcctgacatt aaataaaact ccaaaaatta 2100 aattccggcc ctcaaacccc acaacaggat ttaaccttgc cttcaaggtg tacaataata 2160 gaaaaaagtt ggaattcctt gcctccactg tgagacaaac cccagcaaca tctccagcac 2220 acaagaactt ccaaacacct aaacagcagt ggccaggtgt tcctccagaa ctgcctcccc 2280 caggagcttg ctacaagtgc cagaaatctg gccaccgagc caaggaatgc ccgcagcccg 2340 ggattcctcc taagccgtgt cccatctgtg tgggacccca ctgaaaatcg gactgttcaa 2400 ctcacctggc agcccctccc agagcccctg gaactctggc ccaaggctct ctgactgact 2460 ccttcccaga tcttctcggc ttaatggctg aagactgacg ctgcccgatc gccttggaag 2520 ccccgtagac catcatggac accgagcttt aggtaactct cacagtggaa ggtaagtccg 2580 tcctcttctt aatcaatacg gaggctaccc actccacatt accttctttt caagggcctg 2640 tttcccttgc ctccataact gttgtgggta ttgacggcca ggcttctaaa cctcttaaaa 2700 ctccccaact ctggtgtcaa cttagacaat actcttttaa gcactcctct taattatccc 2760 cacctgcccc gttcccttat taggccgaga cactttaact aaattatctg cttccctgac 2820 tattcctgga ttacagttac atctcattgc tgcccttctt tccaatccaa agcctccttt 2880 gtgtcctcct cttgtatccc ccgaccttaa cccacaagat acctctactc cctccttggc 2940 gacctatcat gcacccctta ccatctcatt aaaacctaat catccttacc ccgctcaatg 3000 ccaatatccc atcccacagc atgctttgaa aggattaaag cctgttatca cttgcctgct 3060 acagcatggc cttttaaagc ctataaactc tccttacaat tcccccattt tacctgtcct 3120 aaaaccagac aagccttaca agttagttca ggatctatgc cttatcaacc aaattgtttt 3180 gcctatccac cccatggtgc caaacccata tactctccta tcctcaatac ctccctctac 3240 tacccattat tctgttctgg atctcaaaca tgctttcttt actattcctt tgcacccgtc 3300 atcccagcct ctctttgctt ttacttggac tgaccctgac acccatcaga ctcagcaaat 3360 tacctgggct gtactgccac aaagcttcac agacagcccc cattacttca gtcaagccca 3420 aatttcttcc ttatctgtta cctatctcag cataattctc ataaaaacac acattctctc 3480 cctgctgatc atgtccgatt aatctcccaa acctcaatcc cttctaaaaa acaagaactc 3540 ttttccttcc tgggcatggt tagtgcggcc agaattctta cacaagagcc aggaccacac 3600 cgtgtagcct ttctgtccaa acaacttgac cttactgttt tagcctagcc ctcatgtctg 3660 cgtgcagcgg ctgccgctgc ttgaatactt ttagaggccc taaaaatcac aaactatgct 3720 caactcactc tctacatttc tcataacttc caaaatctat tttcttcctc atacctgacg 3780 catatactcc ctggctcctt cagctgtact tactctttgt taagtcccac aattaccatt 3840 gttcctggcc cggacttcaa tctggcctcc cacattattc ctgataccac acctgacctc 3900 catgactgta tgtctctgat ccaactgaca ttcaccccat ttccccatat ttccttcttt 3960 ccttttcctc accctgatca cgcttgattt attgatggca gttccaccag gcctaatcac 4020 cacacaccag caaaggcagg ctatgcgata gca 4053 <210> 153 <211> 662 <212> DNA <213> Homo sapiens <400> 153 ttacagtagg tagttagaca gacatgaggc agggaaggcc accctcccca caatgaggaa 60 tgtcaggcaa ccatcaggtg atggtcaggc agttgttaat tgtctctcta aaataatcat 120 tggttgaagc cagggccagg cagtttccca ataaatagaa aacacctgaa actggtgatc 180 agcttcctag taagatctca ggagttgggt gagtggactc aagcatgcgc actaagaggc 240 aaaatggcag agtttaactg gtatatgaat cctcaactga taaggagaaa aagccctcaa 300 gtgagcacgt acacaacttc agtaaacaca ctgcgcacgc tcacccccca agtgcctgaa 360 tgccactgtg gatgcggaca gcccactcca agggaagaat caggggagaa gagatgcaac 420 ccccctggaa gcatgccaac atatgaaaca ccaagtcaaa ggtcaaacca cccggctgat 480 ctcaagtcac ccgcttggcc ctcttctaag tgtacttcct tttgttcctg ctctaaagct 540 ttttaataca cttttcactc ctgctcaaaa acttgccttg gcctctcacc ctgccttatg 600 acccttggtt aaaaattctt tcttttgagg tgttaagaat tgaggttgct acagatttgc 660 ca 662 <210> 154 <211> 1924 <212> DNA <213> Homo sapiens <400> 154 accatcctat taaaacctaa tcactcttac cctgctcaat gccaatatct tatcctatag 60 catgctttga aagaattaaa gcctgttatc attcacctgt tacagcatgg ccttttaaag 120 cttataaact cttcttgaca ttcacctcat ttccccatat ttccttcttt cctcttcctc 180 gccttgatca tgcttgattt attgatggca gttccaccag gcctaattgc cacaccagca 240 aaggcaggct atgctatagt acaagccact atcccacctc ttagaacctc tcatttcctt 300 tccatcgtgg aaatctatcc tcaaggaaat aacttctcag tgttccatct gctattctac 360 tactcctcag ggattattca ggccccctcc cttccctaca catcaagctc aaggatttgc 420 ccccacccag gactggcaaa ttagctttac tcaacatgtc ccgagtcaga taactaaaat 480 acctcttagt ttaggtagac actttcactg gataggtaga ggcctttcct acagggtctg 540 agaaggccac cgcagtcatt tcttcctttc tgtcagacat aattcctcag tttagccttc 600 ccaccactat acagtctgat aacagaccag cctttattag tcaaatcagc caagcagttt 660 ttcaggctct tagtattcag tgaaaccttt atcccttatg gtcctccgtc ttcaagaaaa 720 gtagaatgga ctaaatgtct tttaaaaaca cacctcacca agctcagcca acaacttaaa 780 aaggactgga caatactttt accactttcg cttctcagaa gtcagacctg tcctcaggat 840 gctacagtgt acagcccatt tgagctcctg tatagatgct cctttttatt aggccccagt 900 ctcattccag acaccagacc aacttagact gtgcccccaa aaaacttgtc atccctacta 960 tcttctatct agtcatactc ctattcactg ttctcaacta ctcatacatg ccctactctt 1020 gtttacactg ccagtttgca ttatttctcc aagccatcac agctgatatc tcctggtgct 1080 atccccatac tgccactcta aactcttgaa gtaaataaat aatctgctgg caggactatg 1140 ctgaatctcc ttaggcactc tctaatcaga tgtcctaggt cctcccaatt cttagacctt 1200 ttatacctgt ttttctcctt ctcttattcc atttagtttt tcaattcata caaaaccgta 1260 tccaggccat caccaataat tctacaccac aaatatttct tctaacaact ccacaatatc 1320 accttttacc acaaaatctt ccttcagctt aatctctccc actctaggtt cccacgccac 1380 ccctaatcct gctcgaagta gccctgagaa acattgccca ttatctctcc ataccacctc 1440 caaaaatttt caccatccca acactttacc actatttcat tttatttttc ttattaatat 1500 aagaagacag gaatgtcagg cctctgagcc caagctaagc catcataccc cctgtgacct 1560 gcatgtacac atccagaagg ccagttcctg ccttaactga tgacattcca ccacaaaaga 1620 agtgaaaatg gcctgttcct gccttaactg atgacattgt cttgtgaaat tccttctcct 1680 ggctcatcct ggctcaaaag ctcccctact gagcaccttg tgaccccaac tctgcccgcc 1740 agagaacaac ccccctttga ctgtaatttt cctttatctc cccaaatcct ataagacagc 1800 tccaccctta tctcccttcg cagagtctct tttcggattc agcccgcctg ctctcgggtg 1860 attaaaagct ttattgctca cacaaagcct gtttggtggt ctcttcacat ggaggtgcat 1920 gaaa 1924 <210> 155 <211> 353 <212> DNA <213> Homo sapiens <400> 155 ccacaaaaga agtgaaaata gtcagttcct gccttaactg atgacacacc accactgtga 60 tttgttcctg ccccactcta actgatcaat ggaccttgtg acattccttc tcctggacaa 120 tgaatctcag gagctcccca gtgagcacct tgtgaccccc acccctgccc gcaagagaaa 180 aacccccatt aactgtaatt ttccactacc tacccaaatc ctataaaact gccccacccc 240 tacctccctt tgctgactcc tttttcactc agtccacctg cacccaggag attaaaaagc 300 tttattgctc acacaaagcc tgtttggtgg tctcttcaca tggacacacg taa 353 <210> 156 <211> 6026 <212> DNA <213> Homo sapiens <400> 156 gtcaggcctc tgagcccaag ccaagccatc gcatccactg tgacttgcac atatacaccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa catgccctgc cccaccttaa 120 ctgatgacat tccaccacaa aagaagtgtg aatggcgggt ccttgcctta actgatgaca 180 ttaccttgtg aaagtccttt tcctagctca tcctgcctca aaaagcaccc ccactgagca 240 ccttgcgacc cccactcctg cctgccagag aacaaaccct ctttgactgt aattttcctt 300 tacctaccca aatcctataa aacggcccca cccttatctc ccttcactga ctctcttttc 360 ggactcagcc cgcctgcacc caggtgaaat aaacagccac attgctcaca caaagcctgt 420 ttggtggtct cttcacacag acgcgcatga aatttggtgc catgactcag attgggggac 480 ctcccttggg agatcaatcc cctgtattcc tgttctttgc tccgtgagaa agatccacct 540 atgacctcag gtcctcagac caaccagccc aaggaacatc tcaccaattt taaatcaggt 600 aagcagcctc ttcttactct cttctccaac ctccctcact gtccctcaac cactttctcc 660 tttccaatct tcaatctctc ccttctctta atttcaattc ttttcatttt ctgggagaga 720 caaaggagac atgttttatc catggaccca aaactccggc gccagtcatg gactgggaag 780 gcagccttcc cttggtgttt aatcattgca gggatgcctc tctgattata cacccacgtt 840 tcaagggtgt cagaccacgc aggtacacct gccttggtcc ttcaccctta gcagcaagtt 900 ccgcttttct gggggaaggg gaaagtacct caatcccttc tctccttgtc tctacccctt 960 ctctgctttt ccggggacag gacaagtacc ccaacccctt ctctccttgt ctctacccct 1020 tctctgcttt tctgggagag gggcaagtat ccctcaaccc cttctccttc actcttagct 1080 gcaagtcctg cttttctaga ggaggggcaa gtaccccaac cttgtatctc tgtgccccga 1140 ccccttattt ccatgccccg acaccttatt tctgcacccc attccttatt tccacacgct 1200 gacctctcat ctctgcaccc caaccccttt tcccactttt ctggaaggta agaaccccca 1260 aaccccttcc ctccatttct ctactctctc ttttctctag gcttgcttcc ttcactatgg 1320 gcaactttcc accctccatt cctccttcta ctcccttggc ctgtgttctc aaaaacttaa 1380 aacctcttca actcacacct gatctaaaac ctaaatgact tttcttcttc aatgctgctt 1440 gaccccaata caaactcgac agtagttcca aatagccaga aaatggcact ttgaattttt 1500 ccatcctgca aaatctaaat aattcttgtc gtaaaatagg caaacggtct gaggtgcctg 1560 acgtccaggc attcttttac acatcagtcc cttcctagtc tctgtgccca gtgcaactca 1620 tcccaaatct tccttctttc cctcccgcct gtcccctcag taccaacccc aagtgtggct 1680 gagtctttct aatcttcctt ttctacagac ccatcagacc tctcccttcc tccccaggct 1740 gctcctcgcc aggccgagct aggtcccaat tcttcctcag cctctgctcc tccaccctat 1800 aatcttttta tcacctcccc tcctcacacc tggtcctgct tacagcttcg ttccctgact 1860 agccctcccc ctcctgccca gcaatttact cttaaaaagg tggctggagc caaaggcata 1920 gtcaaggtta atgctccttt ttctttatcc caaatcagaa gcgtttaggc tctttttcat 1980 caaatataaa aacccagccc agttcatgac ttgtttggca gcaaccctga gacgctttac 2040 agccctagac cctaaaaggt caaaaggccg tcttattctc aatatacatt ttattaccca 2100 atctgctccc gacattaaat aaaactccaa aaattggaat ctggccctca aaccccaaaa 2160 caggacttaa ttaacctcac cttcaaggtg tacaataaca gaaaaaagtt gcaattcctt 2220 gcatccactg tgagacaaac cccagccaca tctccagcac acaagaactt ccaaacgcct 2280 gaaccgcagc agccaggcgt tcctccagaa cctcctccca tatgagcttg ctacacatgc 2340 cggaaatctg gccactggac caaggaatgc ccgcagccca ggattcctcc taagccacgt 2400 cccatctgtg tgggacccca ctgaaaatcg cactgttcaa ctcacctggc agccactccc 2460 agagcccctg gaactctggc ccaaggctct ctgactgact ccttcccagg tcttctcggc 2520 ttagcggctg aagactgaca ctgcctgatc gccttggaag ccccctagac catcacggac 2580 gccgagcttc gggtaactct tacagtggaa ggtaagccca tccccttaat caatatggag 2640 gctacccact gcatattacc ttcttttcaa gggcctgttt cccttgcctc cataactgtt 2700 gtgggtattg acggctaggc ttctaaacct cttaaaactc cccaactctg gtggcaactt 2760 agacaatact cttttaagca ctccttttta gttatcccca cctgcccagt tcccttatta 2820 ggctgagaca ctttaaatta tctgcttccc tgactattcc tggactacag ctatatctca 2880 ttgccaccct tcttcccaat ccaaagcctc ctttgcgtcc tcctcttgta ttcccccacc 2940 ttaacccaca agtataaccc acctctactc cctccttagt gaccgatcat gcacccctta 3000 ccatctcatt aaaacctaat cactcttacc ccgctaaacg ccaatatccc atcccacagc 3060 acgctttaaa aagattaaag cctgttatca ctcacctgct acagcatggc cttttaaagc 3120 ctataaactc tccttacaac tcccccattt tacctgtcct aaaaccggac aagccttaca 3180 agttagttca ggatctgcgc cttatcaacc aaattgtttt gcctatccac ccacggtgcc 3240 aaacccatat actctcctat cctcaatatc tgcctctaca acccattatt ctgttctaaa 3300 tctcaaacat gcttttttca ctattccttt gcccccttaa tcccagcctc tcttcgcttt 3360 cacttggact gaccctgaca cgcatcaagc tcagcaaatt acgtaggctg tactgccgca 3420 aagctttaca gacagccccc attacttcaa tcaagcccaa atttcttcct catctgttac 3480 ctatctcggc ataattccca taaaaacaca cgtgctctcc ctgctgacca tgtccgacta 3540 atctctcaaa ccccaacccc ttctacaaaa caacaactcc tttccttcct gggcatggtt 3600 agatactttc gcctttggat acctggtttt gccatcctaa caaaaccatt atataaactc 3660 acaaaaggaa acctagctga ccccatagat cctaaatcct ttccccactc ctctttctgt 3720 tccttgaaga cagctttaga aactgctccc actctagctc tccctgactc atcccaaacc 3780 ttttcattac acacagctga agtgcagggc tgtgcagtcg gaattcttac acaaggacca 3840 ggatcgcatc ctgtagcctt tttgtccaaa caacttgacc ttactgtttt aggctggcca 3900 tcatgtctcc atgcagcagc taccgctgct ttaatacttt tagaggccct caaaatcaca 3960 aactatgctc aactcactct ctacagttct cataacttcc aaaatctatt ttcttcctca 4020 tacctgacgc atatactttc tgcttcccgg ctccttcagc tatactcttt gttgagtctc 4080 ccacaattac tgttgttcct ggcccagact tcaatccggc ctcctacatt attcctgata 4140 ccacacctga gccccatgac tgcatctctc tgatccacct gacattcacc ccatttcccc 4200 aaatttccct ctttcctgtt cctcagcctg atcacgcttg atttattgat ggcggttcca 4260 ccaggcctaa tcgccacaca ccagcaaagg caggttatgc tatagtacaa gccactagcc 4320 cacatcttag aacctctcat ttcctttcca ttgtggaaat ctatcctcaa ggaaataact 4380 tctcagtgtt ccatctgcta ttctactact cctcagggat agttcaggcc ccctcccttc 4440 cctacacatc aagctcaagg atttgccccc acccaggact ggcaaattag ctttactcaa 4500 catgcccgag tcaggaaact aaaatacctc ttagtctaaa tggacacttt cactgaataa 4560 gtaaaggcct ttcctacagg gtctgagaag gccaccacag tcatttcttc ctttctgtca 4620 gacataatta ctcagtttag ccttcccacc tcaatacagt ctgataacag acgagccttt 4680 attagtcaaa tcagccaagc agtttttcag gctcttagta ttcagtgaaa cctttatatc 4740 ccttatggtc ctccgtcttt aagaaaagta gaatggacta aaggtctttt aaaaacacac 4800 ctcaccaagc tcagccacca acttaaaaag gactggacaa tacttttacc actttccctt 4860 ctcagaattc aggcctgtcc tcggaatgct acagggtaca gcccatttaa gctcctgtat 4920 agacgctcct ttttattagg ccccagtctc attccagaca ccagaccaac ttagattgtg 4980 ccccaccccc ccaaaaaaaa aattgtcatc cctactattt tctgtctagt catactccta 5040 ttcaccattc tcaactactc atacatgcct tgctcttgtt tacactgccg gtttacactg 5100 tttttccaag ccatcacagc tgatatctcc tggtgctatc cccaaactgc cattcttaac 5160 tcttgaagta aataaataat ctttgctggc aggactatgc cgaatctcct taagcactct 5220 ctaatcagat atcctgagtc gtcccaattc ttagaccttt tatacctgtt tttcttcttc 5280 tgttattcca tttagttttt caattcatac aaaaccgtat ccaggccgtc accaatcatt 5340 ctatatgaca aatgtttctt ctaacatccc cacaatatca cgccttacca caagacctcc 5400 cttcagctta atctctccca ctctaggttc ccacatcgcc cctaatcccg catgaagcag 5460 ccctgagaaa catcgtccat tctctctcca taccaccacc ccaaaatttt cactgcccca 5520 acacttcaac actattttgt tttatttttc ttattaatac aagaaggcag gaatgtcagg 5580 cctctgagcc caagccaagc catcgcatcc cctctgactt gcacgtatat gcccagctgg 5640 cctgaagtaa ctgaagaatc acaaaagaag tgaacatgcc ctgccccacc ttaactgatg 5700 acattccacc acaaaagaag tgtgaatggc gggtccttgc cttaagtgat gatattacct 5760 tgtgaaagtc cttttcctgg ctcatcctgg ctcaaaaaca cccccactga gcaccttgcg 5820 accccccact cctgcccgcc agagaacaaa ccccctttga ctgtaatttt cctttaccta 5880 cccaaatcct ataaaacggc cccaccctta tctcccttca ctgactgtct ttttggactc 5940 agcctgcctg cacccaggtg aaataaacag ccatgttgct cacacaaagc ctatttggtg 6000 gtctcttcac agggacgcgc ataaaa 6026 <210> 157 <211> 5642 <212> DNA <213> Homo sapiens <400> 157 gtcaggcctc tgagcccaag ctaagccgtc atatcccctg tgacctgcac gtatacatcc 60 agatggcctg aaataactga agaatcacaa agaagtgaaa atggcctgtt cctgccttaa 120 ctgataacat taccttgtga aattccttct cctggctctt ctggctcaaa agctccccca 180 ctgagcacct tgtgaccccc acccctgcca gccaaaaaac aacccccttt gactgtaatt 240 ttccattacc tacccaaatc ctataaaaca gccccacccc tatctccttt tgctgactct 300 tttcggattc agcctgcctg cacccaggtg attaaaaagc tttattgctc acacaaagcc 360 tgtttggtgg tctcttcaca gggacacgca tgaaatttgg tgccatgact cggatcaggg 420 gacctccctt gggagatcaa tcccctgtcc tcctgctctt tgctcagtga gaaagatcca 480 cctatgacct caggtcctca gaccaaccag cccaaggaac atcccaccaa ttttaaaccc 540 ggtaagcagc ctctttttac tctcttctcc aacctctctc actatctctc aacctctttc 600 tcctttcaat cttggcgcca tctttcaatc tctcccttcc cttaatttca gttcctttcc 660 ttttctggca gagacagagg agacgtgttt tatccgtgaa cccaaaactc cagcgctggt 720 cacagactcg ggaagacagt cttcccttgg tgtttaatca ctgcggggat gcctgcttga 780 ttattcaccc acatttcaga ggtgtttgat caccacgggg acacctgcct tgatccttca 840 cccttagtgg caagcaccac taatttgggg ggcaagcacc tcccttctct ccgtgtctct 900 accctccctt ttctctccac tttcctgggg ggcaggcatc ccccacacct tctctccatg 960 tctctatcct ctcttttctc tgggcttacc tccttcacta tgggcaaact tccacccctc 1020 cattcctccc tcttctccct tagcctgtgt tctcaagaat ttaaaacctc ttcaactcac 1080 acgtgaccta aaacctaaac atcttatttt cttctgcaat gccacttaac cccaatacaa 1140 actcaacaat ggttccaaat agccagaaaa cggcactttc gatttctcca tcctacaaga 1200 tctagataat tcttgtcata aaatgggcaa atggtctgag gtacctgaca cccaggcatt 1260 ctttgttccc tccctagtct atttccaatg caattggtcc caaatcttct tttccctccc 1320 acctgtccct tcagtcccaa ccccaagtgt tgttgagtct ttccaatctt ccttttctac 1380 cgacccatct gacctctccc ctcatcccca gactgctcct caggtcactc cccagccagg 1440 ctgaatcagg ctccaattct tcctcagttt ctgctcctcc accctataat ccttctatca 1500 ccccctctcc ccaaacccag tccagcttac agtttcgttc tgcaactagc cctcccccat 1560 ctgcccagta atttcctctt aaaaaggtgg ctggagctaa aggcatagtc aaggttaatg 1620 ctcctttttc tttatccgaa ctctcccaaa tcagttagtg tttaggctct ttttcctcaa 1680 atataaaaac ccagcccagt tcatggctca tttggcagca accctgagac gctttacagc 1740 cctagaccct gaagggtcag aaggctgtct tattctcaat atgcatttta tcacccagtc 1800 agcccctgac attagaaaaa agcttcaaaa attagaatcc ggccctcaaa cctcgcaatg 1860 ggaattaatc aaccttgcct tcaaggtgta caataataga aaggaggcag ccagacagca 1920 acacatttct gagttacaat tacttgcctc tgctgtgaga caaaacccag ccgcatctcc 1980 agcatacaag aacttcaaaa cgcctgaact gcagcggcca ggcattcctc caggaccacc 2040 tgccccagga tcttgcttca agtgctggaa atctggccac tgggccaagt attgcctgca 2100 gcctgggatt cctcctaagc catgtcccat ctgtgcagga ccccactgga aactggactg 2160 tccaactcac ccagcagcca ctcccagagc ccctggaact ctggcccaag gctatctgac 2220 tgactccttc ccagatcttc tccgcttagc ggctgaagac tgatgctgcc caatcgcctc 2280 agaagcttcc tggatcatca cagatgcttt aggtaactct tacagtggag ggtaagtccg 2340 tccccttctt aatcaatatg gaggctacca actccacatt accttctttt caagggccta 2400 tttcctttgc ctccacaact attgtgggta ttgacagcca ggcttctaaa cctcttaaaa 2460 cttcccaact ctggtgccaa cttggacaat attcttttat gcactccttt ttagttatcc 2520 ccacctgccc agttccctta ttaggtcaag acattttaac taaattatct gcttccctga 2580 ctattcctgg gctacagcca caccttattg ccaccctttt ccccagttta aagcctcctt 2640 cacatcctcc ccttgtatct ccccacctta atccacacat atgggacatg tctactccct 2700 ccttggtgac tgatcatgca ccccttacca tcccattaaa acctaatcac ccttaccctg 2760 ttcaatgcta atatcctatc ccacagcatg ctttaaaaag attaaagcct gttatcactt 2820 gcctgttaca gcatggcctt ttaaagccta taatctctcc ttataattcc cccattttac 2880 ctgttcaaaa accagacagg tcttacaggt tagtgcagga tctgtgcctt atcaaccaaa 2940 ttgttttgcc tatccacccc atggtgccaa actcatatat gctcctatcc tccatacctc 3000 cctccacaac ccattattct gttctggatc tcaaacatgc tttctctact attcctttgc 3060 acccttcatc ccagcctctc ttcactttca cttggactga ccctgacacc catcaggctc 3120 agcaaattac ctgggctgta ctgctgcaag tcttcacgga caggccccat tacttcagtg 3180 aaccccaatt tcttcctcat ccattaccta tctcaacata attcttcatg aaaacacaca 3240 tgctctccct gctgatcacg tccagctaat ctcacaaacc ctaacccctt ctacaaagca 3300 acaatgcctt tccttcctag gcatggttag atactccacc tttggatacc tagttttacc 3360 atcctgacta aaccattata taaacttaaa aatgcaaact tagctgatcc catagatcct 3420 aaattctttc gccactcctc tttctgttcc ttaaaaacag ccctagaagc tgctcccaca 3480 ctagctctct ctaactcatc caaccctttt tcattacaca cagctgaagt gcagggctgt 3540 gcggtcagaa ttcttacaca agagccagga ccgcgcccgg cagcctttct atccaaacaa 3600 cttgacctta ctgttttagc ctagccctca tgtctgtgta cggcagctgt cgctgcttta 3660 atacttttag aggccctcaa aatcacaaac tgtgctcaac tcactctctc cagttctcat 3720 aacttccaaa atctattttc ttcctcacac ctgatgcata tactttctgc cccgctccac 3780 tacctctcag caagctgaac tcattgcctt aactggagcc ctaacccttg caaatgaatt 3840 acacgtcaat atttatactg actctaaaga tgccttccat atcctgcacc accatgctgt 3900 tgtatgggct gaaagaggtc tcctcactac acaagggtcc tccatcttaa tgcctcttta 3960 ataaaaactc ttctcaaggc cgctttactt ccaaaggaag ctggagtcat tcactgcaag 4020 ggccatcaaa aggcatcaga tcccattgct ctgggcaatg cttatgctga taaggtagct 4080 aaaaagcagc tagcattcca acttctatcc ctcacagcca gtttttctcc ttctcatcgg 4140 tcactcccac ctactcccct actaaaactt ccacctatca atctcttccc acacaaggca 4200 aatggttctt agaccaagga aaatatctcc ttccagcctc acaggcccat tctattctgt 4260 cgtcatttca taacctcttc catgtaggtt acaagccact agcccacctc ttagaacctc 4320 tcatttcctt tccatcatgg aaatctatcc acaaggaaat cacttctcag ggttccatct 4380 gctagtctac tactcctcag gaccctccct tccctacaca tcaagctcag ggatttgcct 4440 ctgcccagga ctggcaaatt gactttactc acatgcccca agtcaggaaa ctaaaatacc 4500 tcttggtcta ggtagacacg ttcaccggtt gggtagagac ctttcccgta gggtctgaaa 4560 aggccaccac gatcatttct tcccttctgt cagacataat tcctcggttt ggccttccta 4620 cctctataca gtctgataac agaccagcct ttattagtca aatcactcaa gcagtttctc 4680 aggctcttgg tattcagtga aaccttcata ccccttaccg tcttcaatct tcaggaaagg 4740 taaaacggac taatggtctt ttaaaaacac acctcaccaa actcagcctc caacttaaaa 4800 aaaggactct gtcaagaata gagcccaaaa actcaccaac caaacaagta attacactga 4860 atccccttgg gcactctcta atcggatgtc ctgggtcctc ccaattctta gtcctttaat 4920 acctgttttt ctccttctct tattcagacc ttgtgtcttc catttagttt ttcagttcat 4980 acaaaattgc atccaggcca tcaccaatca ttctacatga caaatgctcc ttttaacaac 5040 cccacaatat caccccttac cacaaaatct tcctttggct taatctctcc cactctaggt 5100 tcccacactg cccttaatcc tgcttgaagc agccctgaga aacattgccc attatctctc 5160 cataccaccc ccaaaatttt tgctgcccca acacttcaac actattttat gttatttttc 5220 ttactaatat aagaagacag gaatatcagg cctctgagcc caagctaagc catcatgtcc 5280 cctgtgacct gcacgtatgc acccagatgg cctgaagtaa ctgaaggatc acaaaagaag 5340 tgaaaacggc ctgttcctgc cttaactgat gacattacct tgtgaaattc cttctcctgg 5400 ctcatcctgg ctcaaaagct cccccactga gcaccttgtg tcccctgccc gtgcctgcca 5460 aagaacaacc cctttgactg taattttcca tgacctaccc aaatcctata aaacggcccc 5520 acccctatct cccttcgctg actctcttta cggacttagc ccacctgcac ccaggtgatt 5580 aaaaagcttt attgctcaca caaagcctgt tcagtggtct cttcacaggg acacgcgtga 5640 aa 5642 <210> 158 <211> 5784 <212> DNA <213> Homo sapiens <400> 158 gtcagacttc tgagcccaag ctaagccatc atatcccctg tgacctgcac gtacacatcc 60 agatcgctgg ttcctgcctt aactgatgac attccaccac aaaagaagtg aaaatggcct 120 gttcctgcct taactgatga cattgtcatg tgaaattcct tctcctggct catcccagct 180 caaaagctcc tccactgagt accttgtgac cccccactcc tgcctgccag agaacaacac 240 ccctttttcc tttacctacc caaatcctat aaaacggccc cacccctatc tcccttcact 300 gactcttttc ggactcagcc tgcctgcacc caggtgaaat aaacagccac gttgctcaca 360 caaagcctgt ttggtggtct cttcacatgg atgcgcatga aatttggtgc cgtgactcag 420 atcgggggac ctcccttggg agatcaatcc cctgtcctcc tgctttttgc tccatgagaa 480 atgtccacct acgacctcag gtcctcagac cgaccagccc aaggaacatc tcaccaattt 540 caaatccggt aagaggcctc tttttactct cttctccaac ctccctcact atccctcaac 600 ctctttctcc tttcagtctt ggcaccacac ttaatctctc ccttctctta atttcaattc 660 ctttcatttt ctggtagaga caaaggagac acattttatc catggaccca aaactccggc 720 accagtcatg gactgggaag gcagccttcc cttggtgttt aatcattgca gggacgcctc 780 tctgattatt cacccatgtt tcagaggtgt cagaccacgc agggatgcct gctttagtcc 840 ttcaccctta gcggcaagtc ccgcttttct gtgggagggg caagtacccc aaccccttct 900 ctccatgtct ctaccccttc tctgcctttc tggggggcaa gaaaccccca accccttctc 960 cttcaccctt agcagcaagt cctgcttttc taggggaggg tcaagtacca caacccctta 1020 tatctctgtg ccccgatccc ttatttccac accccaacct cttatatctc tgtgccccga 1080 tcccttattt ccacacccca acctcttata tctctgtgcc ccgatccctt atttctgcac 1140 cccaacctct tatatctctg tgccccaatc ccttatttcc acgccccaac ctcttatatc 1200 tctgtacccc aatcccttat ttccacaccc tgatgtcgta tctctgtgcc ccaacccctt 1260 ctctgctttt ctggagggca agaatacccc accctttctc tgtgtctcta ctgttttctc 1320 tgggcttgcc tccttcacta tgggcaagct tccaccttgc ccattcctcc ttcttctccc 1380 ttagcctgtg ttcttaagaa cttaaaacct cttcaactct cacctgacct aaaatctaag 1440 catttgattt tcttctgcaa tgccgcttga ctccaataca aactcgacag tagttccaaa 1500 taaccggaaa acggcacttt caatttttcc atcctacaag atctaaataa ttcttgtcat 1560 aaaatgggca aatggtctga ggtgcctgac atccaggcat tcttttacac atcggtccct 1620 ccctagtctc tgtgcccaat ggaactcgtc ccaaatcttc cttctttccc tcccgcctgt 1680 cccctcagtc ccaaccccaa gcgtcactga gtctttctaa tcttcctttt ctacagaccc 1740 atctgacctc tcccctcctc cccaacctgc tcctcgccag gccgagctag gtcccaattc 1800 ttcctcagcc tccgctcctc caccctataa tccttttatc acctcccctc ctcacacccg 1860 gtctggttta cagtttcatt ccgtgagtag ccctccccca cctgcccagc aatttcctct 1920 taaaaaggtg gctgaagcta aaggtatagt caaggttaat gctccttttt ctttattaga 1980 cctctcccaa atcagtgagc atttaggctc tttcatcaaa tatgaaaaac tcagcccagt 2040 tcatggctca tttggcagca accctgagac actttacagc cctagaccct aaaaggtcaa 2100 aaggccgtct tattctcaaa atacatttta tcacctaatc tgctcccgac attaaataaa 2160 actccaaaaa ttaaattcca gccctcaaac cccacaacag gatttaatta accttgcctt 2220 caaggtgtac aataatagaa aaaagttgca attccttgcc tccactgtga gaaaaacccc 2280 agccacatct ccagcacaca agaacttcca aatgcctgaa ccgcagcagc cagaacctcc 2340 tcccccagga gcttgctaca agtgccagaa atctggccac caggccaagg aatgcctgct 2400 gcccaggatt cctcctaagc cgcgtcccat ctgtgcagga ccccactgga aatcggactg 2460 tccaactcac ctggcagcca ctcccagagc ccctggaact ctggcccaag gctctctgag 2520 tccttcccag atcttcttgg ctcagcggct gaagattgac actgcccgat cacctcggaa 2580 gccccctaga ccatcacgga cgccgagctt tgggtaactc tcacagtgga aggtaagtcc 2640 gtccccttag tcaatacgga gggcacccac tccacattac cttcttttca agggcctgtt 2700 tcccttgcct ccataactgt tgtgggtatt gatggccagg cttctaaatc cctgaaaact 2760 ccccaactct ggtgccaact tggacaacac tcttttatgc actctttttt agttatcccc 2820 acctgcccag ttcccttatt aggctgagat attttaacca aattatctgc ttccctgact 2880 attcctggac tacagccgca tctcattgcc acccttctcc ccaacccaaa gcctccttcg 2940 cgtcttcctc tcgtatcccc ccaccttaac ccacaagtat gggacatctc tactccttcc 3000 ctggcaaccg atcacatgcc cattaccatc ccattaaaac ctaattaccc ttaccccgct 3060 caatgccaat atcccatccc acagcacgct ttaaaaggat taaagcctgt tatcactcgc 3120 ctgctacagc atgggcttct aaaacctata aactctcctt acaattcccc cattttacct 3180 gtctaaaaac cggacaagtc ttacagatta gttcaggatc tgcgccttat caaccaaatt 3240 gttttgccat ccatcctgtg gtgcccaacc catacactct tttgtcctca ataccttcct 3300 ccacaactca ctattccgtt ctcgatctta aagatgcttt tttcactatt cccctgcacc 3360 cctcttccca gcctctcttt gctttcactt agactgaccc cgacacccat taggctcagc 3420 aaattacctg ggctgtactg ccgcaaagct tcacagacag cccccattac ttcagtcaag 3480 ctgaaatttc ttccttatct gttacctatc tcagcataat tctcataaaa acacacgtgc 3540 tttccctgct gatcgtgtcc gattaatctc ccaaacctca atcccttaca aaacaacaac 3600 tcctttcctt cctaggcatg gttagtgcag tcagaattct tacacaagag ccaggaccac 3660 accctgtagc ctttctgtcc aaacaacttg accttactgt tttagcatag ccatcatgtc 3720 tccgtgcagt ggctgctgcc gccctaatac ttttagaggc cctcaaaatc acaaactatg 3780 ctcaacttac tctctacatt tcttataact tccaaaatct attttcttcc tcatacctga 3840 tgcatatact ttctgctccc cggctccttc agctgtactc actctttgtt aagtcccaca 3900 attaccatag ttcctggccc ggacttcaat ccggcctccc acattattct ggataccaca 3960 cctgaccctc atgactgcat ctctctgatc cacctgacat tcaccccatt tctccatatt 4020 tccttctttc ctgttcctca ccctgatcac gcttgattta ttaatggcag ttccaccagg 4080 cctaatcgcc acacaccagc aaaggcaggc tatgctatag tacaagccac tagcctgcct 4140 cttagaacct ctcattttct ttccatcgtg gaaatctatc ctcaaggaaa taacttctca 4200 gtgttccatc tgctattctg ctactcctca gggattattc aggctccctc ccttccctac 4260 acatcaagct caaggatttg cccccaccca ggactggcaa attagcttta ctcaacatgc 4320 gagtcagata actaaaatac ctcttagtct aggtagacac tttcactgga taagtagagt 4380 cctttcctac aaggtctgag aaggccaccg cagtcacttc tttccttctg tcagacataa 4440 ttcctcagtt tagccttccc acctctatac agtctgataa cagaccagcc tttattagtc 4500 aaatcagcca agcagttttt gaggctctta gtattcagtg aaacctttat atcccttaca 4560 gtcctcagtc ttcaggaaaa gtagaacgga ctaaaggtct tttaaaaaca cacctcacca 4620 agctcagcca ccaacttaaa aaggactgga caatactttt accactttct cttctcagaa 4680 gtcagacctg tcctcagaat gctacagggt acagcccatt tgagctcctg tatagatgct 4740 cctttttatt aggccccagt ctcattgcag acactagacc aacttagact gtgcccccaa 4800 aaaacttgtc atccctacta tcttctgtct agtcatactc ctattcaccg ttctgaacta 4860 ctcatacatg ccctgctctt gtttacactg ccggtttaca ctgtttctcc aagccatcac 4920 agctgatatc tcctggtgct atccccaaac tgccactctt aactcttaaa gtaaataaat 4980 aatctttgct ggcaggacta tgctgaatct tcttaggcgc tctctaatca gatgtcctga 5040 atcgtcccaa ttcttagacc tcttatacct gtttttctcc ttctcttatt ccatttagtt 5100 tttcaattcg tacaaaactg tatccaggtc atcaccaata attctaaatt acaaatgttc 5160 cttataacaa ccccacgata tcacccctta ccacaaaatc ttccttcagc ttaatctctc 5220 ccactctagg ttcccacact gcccctaatc ctgctggaag cagccctgag aaacatcacc 5280 cattatctct ccataccacc cccaaaaatt ttcaccatcc taacacttta ccactatttc 5340 attttatttt tcttattaat ataagaagac aggaatgtca ggccgctgag cccaagctaa 5400 gccatcatat cccctgtgac ctgcacgtac acatccatat ccccggttcc tgccttaact 5460 gatgacattc caccacaaaa gaagtgaaaa tggcctgttc ctgccttaac tgatgacatt 5520 gtcttgtgaa attccttctc ctggctcatc ctggctcaaa agctccccca ctcagtacct 5580 tgtgatcccc cactcctgcc tgccagagaa caacccccct ttttccttta cctacccaaa 5640 tcctataaaa cggccccacc cctatctccc tttgctgact ctcttttcgg actcagccca 5700 cctgcaccca ggtgaaataa acagccatgt tggttgctca cacaaagcct gtttggtggt 5760 ctcttcacac agatgcgcat gaaa 5784 <210> 159 <211> 277 <212> DNA <213> Homo sapiens <400> 159 gtaggagatc agtcagggtg gcgggaaaaa ctgtggaaag atgcaaacct tcttggaagg 60 ctgggaggtt ttacaaaagc ttcggaaaag gatttggctg aaggcagcca gattctctta 120 tccggtgcct aaaagcttag gttagataga aaggggatga ggggtgacca tgttaattac 180 ccacaagtgt gttgactcaa ggcctctgtc attaaatctg tactaaataa atgcctgcag 240 ccccagcttg tcagggctgc agctgctaca actcttt 277 <210> 160 <211> 3555 <212> DNA <213> Homo sapiens <400> 160 gtcagtcctc tgagcccaag ctaagccatc attatctcct gtgacctgca tgtacatatc 60 cagatggccg gttcctgcct taactgatga cattatcttg tgaaattcct tctccttgct 120 catcctggct ccaaagctcc cctactgagc accttgtggc ccccactcct gcctgccaga 180 gaacaacccc cctttttcct ttacctaccc aaatcctata aaattgcccc acccctatct 240 cccttcactg actctctttt tggactcagc ccacctgtac ccaggtgaaa taaacagctt 300 tactgctcac acaaagcctg tttggtggtc tcttcacatg gatgcatgtg aaatttggtg 360 ccgtgactgg gatcgaggga cttcccttgg gagatcaatc ccctgtcctc ctgctctttg 420 ctctgtgaga aagatccacc tatgacttca ggttctcaga ctgaccagcc caagaaacat 480 ctcaccaatt tcaaatctgg taagcggctt ctttttactc tcttctccaa cctccctcac 540 tatccctcca cctctttctc ctcccaatct tggcaccaca cttcaatctc tcccttctct 600 taatttcaat tcctttcatt ttctggtaga gacaaagggg acacgtttta tctgtggacc 660 caaaactctg gcaccagtca cggactagtg aaggcagcct ttccttggtg tttaatcact 720 tgcagggaca cctctctgat tattcaccga ggtttcagag gtgtcagacc atgcagggat 780 gcctgccttg ttccttcacc cttagcagca agacctgctt ttctggggga gggacaagaa 840 cccctcaacc ccttctcctt cacccttagc agcatgtccc acttttctgg gggagggaca 900 ggaaccccga cctcttatct ctgcaccccg atcccttatt tccatgccct gacctcatct 960 ctgtgtcccg atcccttatt tccacaacct gacctcttat ctctgcaccc caacccttta 1020 tttctgtgcc cccaaccctt tccctctatt ctggaaggca agaacccccc accccttctc 1080 tccatgtctc tactctctct tttctctagg cttgcctcct tcactatggg caagcttccg 1140 ccttccattc ccctttcttc tcccttaccc tgtgttcttc aaaacctaaa acctcttcaa 1200 ctcacacctg acctaaaacc taaatgcctt attttcttct acaatgctac ttgaccccaa 1260 tacaaactca gcagtggttc caaatagcca gagaatggca ctttcaattt ttccatccta 1320 caagatctag atacttcttg tcataagatg ggcaaatgat ctgagatgcc tgatgtccag 1380 gcattctttt acacattggt ccctccctag tctctgttcc cagtgcaact catccgaaat 1440 cttcctcctt tccctcccac ctgtcccctc agtcccaacc ccaagtgtcg ctgagtcttt 1500 ctaatcttcc ttttctacag acccatctga cctctcccat cctggccagc ctgagctagg 1560 tcccaattct tcctcagcct ccacttctcc accctataat ccttttatca cctcccctcc 1620 tcacactggg tctggcttac agtttaattc cgtgactagc cctcccccac ctgcccagca 1680 atttactctt aaacaggtgc ctggagctaa agacatagtc aaggttaatg ctcctttttc 1740 tttatcccaa atcagatagc atttagcctc tttttcatca aatataaaaa tccaccccag 1800 ttcatggctc gtttggcagc aaccctgaga tgctttacag ccctagacct taaaacgtca 1860 aaaggccgtc ttattctcaa tatacatttt attacccaat ctgctcccga cattaaataa 1920 aactccaaaa ttaaattccg gccctcaaac cccacaacag gacttaatta acctcaactt 1980 caaggtgtac aataatggag tagaggcagc ctagcagcaa catatttctc agttgcaatt 2040 ccttgcctcc actgtgagac aaagcccagc caaatctcca gcacacaaga acttccaaac 2100 gcctaaagcg cagtggccag gcattcctcc agaaccacct accccaggag cttgctacaa 2160 gtgccagaaa tctggccacc agaccaagga atgcctgcag cccgggattc ctcctgagcc 2220 atgtcccatc tgtgcgagac ccaactagaa atcggactgt tcaactcacc tggcagccac 2280 tcctagagcc cctggaactc cagcccaagg ctctctgact cattccttcc cagatcttct 2340 tggcttagca gctgaagact gacactgcct gatagatcac ctcggaagcc tacaggacca 2400 tcacagacgc tctaggtaac tctcacagtg gaggagaagt ccatcccctt cttaatcaat 2460 acggaggcta accactccac attaccttct tttcaagggc ctgtttccct tgtctccata 2520 actgttgtga gtattgacag ccaggcttct aaacctctta aaactcccca actctggtgc 2580 caacttagac aatactcttt taagcactcc tttttagttg tccccacctg cccagttccc 2640 ttattaggct gagacacttt aactaaatta tctgcttccc tgactattcc tggactacag 2700 ccactcctca ttgccaccca ccttaaccca caagtagaag atacctctat tccctccttg 2760 gcaacctatc acgcacccct taccatctca ttaaaaccta atcactctta cccctctcaa 2820 tgccaatatc ccatcccaca gcatgctttg aaaggattaa agcctgttat cactcacctg 2880 ctacagcatg gccttttaaa gcctataaac tctccttaca attcccccat tttacctgtc 2940 ctaaaaccag acaagcctta caagttagtt caagatctgt gccttatcaa ccaaattgtt 3000 ttgcctatcc accccaaggt gccaaacaca tatactctcc tatcctcagt tcctccctcc 3060 acaacccatt attctgttct gaatctcaaa catgctttct ttactattcc tttgcaccct 3120 tcatcccagt cactcttcgc tttcacttgg actgaccctg acacccatca agctcagcaa 3180 attacctggg ctgtactgtc gcaaagcttc acagacagcc cccattactt cagtcaagcc 3240 caaatttctc ccttatctgt tacctatctc agcataattc tcataaaaac acacgtgctc 3300 tctctgccga tcgtgtgtga ctcatctctc aaaccccaac cccttctaca aaacaacaac 3360 tcctttcctt cctgtgcatg gttggatact ttcaccttta gatatctggt tttgccatcc 3420 taacaaaacc attatataaa ctcacaaaag gaaacctagc tgaccccata gatcctaaat 3480 cctttcccca ctcctctttc tgttccttga agacagcttt aaagactgcc cccaccctag 3540 tcttggttcc ctgac 3555 <210> 161 <211> 381 <212> DNA <213> Homo sapiens <400> 161 gtcaggcctc tgagcccaag ctaagccatc atattccctg tgacctgcag gtatacatcc 60 agatggcctg aagcaactga agaatcacaa aagaagtgga agtggtcagt tcctgcctta 120 actgatgaca ttaccttgtg aaattccttc tcctggctca gaagctcccc cactgagcac 180 cttgtgaccc cggcccctgc ccaccagcga acaagcccct ttgactgtaa ttttccatta 240 cctactcaaa tcctataaaa tggctccacc tctatctccc ttcactgact ctcttttagg 300 actcagcctg cctgcaccca ggtgattaaa aagctttatt gctcacacaa agcctgtttg 360 gtgatctctt catacggaca c 381 <210> 162 <211> 796 <212> DNA <213> Homo sapiens <400> 162 gagagacagg actagccgga tttcctaggc caactaagaa tccctaaccc tagctgggaa 60 ggtgaccgtg tccaccttta agcatggggc ttgcaactta gctcacaccc aaccaatcag 120 atagtaaaga gagctcacta aaatgctaat taggcaaaaa caggaggtaa agaaatagcc 180 aatgatctat cgcctgagag cacagcagaa gagacaatga tcaggatata aacacaggca 240 ttcgagccgg caatggcaac cccttcaggt cccctccctt tgtatgggag ctctgttttc 300 actctattaa atcttgcaac tgcactcttc tggtccctgt ttgttacggc tggagctgag 360 ctttcgctcg ccgcccactg atgctggccg ccgtcacaga cccaccgctg acttccatcc 420 ccctggatcc cgcagggtgt ccgctgtgct cctgatccag caaggcgccc actgctgctc 480 ctgatcgggc taaaggcttg tcattgttcc tgcacagcta agtgtccggg ttcgtcctaa 540 tcgagctgaa cactagtcac tgggttccat ggttctcttc cgtgacccac ggctcctaat 600 agagctataa cactcaccgc atggcccaag attccattct ttggaatccg tgaggccgag 660 aaccccacgt cagagaatac gaggcttgcc accatcttgg aagcagcccg ccaccatctt 720 ggaagcagcc cgccaccatc ttggaagcag cccaccacca tcttgggagc tctgggagca 780 aagacccctg gtaaca 796 <210> 163 <211> 5089 <212> DNA <213> Homo sapiens <400> 163 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgactgcacg tacacatcca 60 gatggcgggt tcctgcctta actaatgaca ttccaccaca aaagaagtga aaatggcctg 120 ttcctgcctt aactgatgac attaccttgc gaaattcctt ttcctggctc atcctggctc 180 atcccagctc aaaagctccc ccactgagca ccttgtgacc cccacccctt cccgccagag 240 aacacctccc ctttgactgt aattttcctt tacctaccca aatcttataa aatggcccca 300 cccctatctc ccttcgctga ctctcttttc ggactcagcc catctgcacc caggtgaaat 360 aaatagcctt gttgctcaca caaagcctgt tagaatcgtc ccaaattctc cttctttccg 420 tctcgcctgt cccctcagtt ccaaccccaa gcgtcactga gtctttcttc cttttctaca 480 gacccatctg gcctttcccc tcctccccag gctgctcctt gccaggccga gctaggtccc 540 aattcttcct cagcctctgc tcctccaccc tataatcttt ttatcaccgc ccctcctcac 600 acctggtccg gcttacagtt tcgttccacg actagccctc ccccacctgc ccagcaattg 660 gtggctggag ctaaaggcat agtcaaggtt aatgctcctt ttcctttttc cttatcccac 720 ctctcccaaa tcagttagtg tttaggctct ttttcatcaa atatgaaaaa cccagcccag 780 ttcatggctc atttggcagc aaccctgaga tgctttatag ccctagacct aaaaggtcaa 840 aaggccgtct tattctcaat atacatttta ttacccaatc cgctcccgac tttaaagctc 900 caaaaattaa attccggcca tcaaaccccg caacaggact tagttaacct caccttcaag 960 gtgtacaata atagaaaaaa agttgcaatt ccttgcctcc actatgagac aaaccccagc 1020 cacatctcca gcacacaaga acttccaaac gcctgaaccg cagtcggcca ggtgttcctc 1080 cagaacctcc tctcccagga gcttgctaca agtactggaa atctggccac cgagccaagg 1140 aatgcccaca gccccggatt cctcctaagc cgcatcccat ctgtgcggga ccccactgaa 1200 aatcggactg ttcaactcac ctggcagcca ctcccagagc ccctggaact ctggcccaag 1260 gctctctgac tgactccttc ccagatcttc tccacttaga ggctgaagac tgacactgcc 1320 cgatcgcctc ggaagccccc tagaccatca tggatgccag gcttcgggta actctcacag 1380 tggagggtaa gtccgtcacc ttcttaatca atacagaggc tactaattcc atattacctt 1440 cttttcaagg gcctgtttcc cttgcctcca taactgttgt gggtattgac ggccaggctt 1500 taaacctctt aaaactcccc aactctgctg ccaacttgga caacattatt ttatgcactc 1560 ttttttagtt atccccgcct gcccagctcc cttattaggt cgagacattt taactaaatt 1620 atctgcttcc ctgactattc ctaggctaca gccacacctc attgccacct ttccccccag 1680 ttcaaagcct cctttgcatc ctcctgtcat atccccccac cttaacccac cagtatggga 1740 tacctctact ccctccttgg cgaccgatca tgcacccctt accatctcat taaaacctaa 1800 tcacccttac cccgttcaat gccaatatcc catcccacaa cacgctttaa aaggattaaa 1860 gcctgttatc actcacctgt tacagcatgg ccttttaaag cctataaact ctccttacaa 1920 ttcccccatt ttacctgtcc tagaaccaga caagccttac aggttagttc aggatctgtg 1980 ccttatcaac caaattgttt tgcctatcca ccccgtcgtg ccaaacccat atactctcct 2040 atcctcaata cctccctcca caacccatta tttctgttct ggatctcaaa catgctttct 2100 ttactatccc tttccaccct tcatcccagc ctctctttgc tttcacttag actgaccctg 2160 acacccatca ggctcagcaa attacctggg ctgtactgcc acgaggcttc acagatagcc 2220 cccattactt cagtcaagcc caaatttcat ccttatctgt tacctatctc ggcataattc 2280 tcataaaaac acatgtgctc tccctgctga tcgtgtctga ctaatctccc aaacctcaat 2340 cccttctaca aagcaataac tcctttcctt cttaggcatg gttagtgtgg tcagaattct 2400 tacacaggag ccgggaccac accctgtagc ctttctgtcc aaacaacttg accttactgt 2460 tttagcctag ccctcatgtt tgcgttcagc ggctgccggt gctttaatac ttttagaggc 2520 cctaaaaatc acaaactatg ctcaactcac tctctacagt tcttataact tccaaaatct 2580 attttcttcc tcatacctga cgcatatagt ttctgctccc cggctccttc agctatactc 2640 actctttgtt gggtctccca caattaccat tgttcctggc ctggacttca atccggcctc 2700 ccacattatt ctggatacca cacctgaccc tcatgactgt atctctctga tccacctgat 2760 attcacccca tttccctata tttccttctt tcctgttcct caccctgatc acatttggtt 2820 tattaatggc agttccacca ggcctaattg ccactcacca gcaaaggcag gctatgctat 2880 agtatcttcc acatgtatca ttgaggctac cactctgccc ccctccacta cctctcaaca 2940 agctgaacta gttgccttaa ctcaagccct cactcttgca aaaggactac gcatcaatat 3000 ttatactgac tctaaatatg cctttcatat tctgcaccac catgctgttg tatgggctga 3060 aagaggtttc ctcactacgc aagggtcctc catcattaat gcctgtttaa taaaaactct 3120 gctcaaggcc gctttacttc caaaggaagc tggagtcatt cactgcaaag gccatcaaaa 3180 ggcatcagat ccctttgctc taggcaatgt ttatgctaag gtggctagac aagcagctag 3240 ctttccaact tctgtccctc atggccagtt tttctccttc acgtcagtca ctcccaccta 3300 ctcccccgct gaaacttcca cctatcaatc tcttcccaca caaggcaaat ggttcttaga 3360 ccagggaaaa tatctccttc cagcctcaca ggcccattct attctgtcat catttcataa 3420 cctcttccat gtaggttata agccgctagc ctgcctctta gaacctctca tttcctttcc 3480 atcgtggaaa tctgtcctca aggaaatcac ttctcagtgt tccatctgct attctactac 3540 ccctcaggga ttgttcaggc ctcctccctt tcctacacat aaagctcggg gatttgcccc 3600 tgcccaggac tggcaaattg actttactca catgccccga gtcagaaaac taaaatacct 3660 cttagtctgg gtagacaatt tcactggatg ggtagaggcc tttcctacag ggtctgagaa 3720 ggccactgcg gtcatttctt cccttctgtc agacataatt ccttggtttg gccttcccac 3780 ctctatacag tccgatagca gaccagcctt tattagtcaa atcagccaag cagtttttca 3840 ggctcttggt attcagtgaa acctttatat cccctacggt cctcagtctt caggaaaggt 3900 agaatggact aatggtcttt taaaagcaca cctcaccaag ctcagccacc aacttaaaaa 3960 ggaatggaca atactcttac cactttccct tctcagaatt caggcccgtc ctcggaatgc 4020 tacagggtac agcccatttg agctcctgta tggatgctcc tttttattag gccccagcct 4080 cattccagac accagatcaa cttggactgt gcccccaaaa aacttgtcat ccctactatc 4140 ttctgtctag tcatacacct attcaccatt ctcaactact cataaatgcc ctgctcttgt 4200 ttacactgcc ggtttatact gattctccaa gccatcacag ctgatatctc ctggtgccat 4260 ccccaaactg ccactcttaa cacttaaagt aaataatctt tgctggcagg actatgctga 4320 atctccttag gcactctcta attagatgtc ctgggtcctt ccaattctta gacctttaat 4380 acctgttttt ctccttctct tattctgttt agtttttcaa ttcatacaaa accatatcca 4440 ggccatcacc aataattcta aatgacaaac gtttcttcta acaaccccac aatatcaccc 4500 cttaccagaa aatcttcctt cagcttaatc tctcccactc taggttccca caccgcccct 4560 aatcccgctc gaagcagccc tgagatacat tacccattat ctctccatac caccccccaa 4620 aatttttgcc gtcccaacac tttaccacta tttcgttttt ttattattaa tttaagaaga 4680 caggaatgtc agacctctga gcccaagcta agccatcata tcccctgtga cctgcacgta 4740 cacatccaga tggccggttc ctgccttaac tgatgacatt ccaccacaaa agaagtgaaa 4800 atggcctgtt cctgccttaa ctgatgacat taccttgcga aattcctttt cctggctcaa 4860 aagctccccc actgagcacc ctgtgacccc cacccctgcc tgccagagaa cacccccctt 4920 tgactgtaat tttcctttac ctacccaaat cttataaaac ggccttaccc ctagctccct 4980 tcgctgactc tctttttgga ctcagcccgc ctgcacccag gtgaaataaa tagccttgtt 5040 gctcacacaa agcctgtttg gtggtctctt cacacggacg caagtgaaa 5089 <210> 164 <211> 44 <212> DNA <213> Homo sapiens <400> 164 tgttaacaga ttggagggct gttaatgctg tgattcaacc catg 44 <210> 165 <211> 980 <212> DNA <213> Homo sapiens <400> 165 gtggagaaaa gaaagagaga tcagattgtt actgtgtcta tgtagtaaag gaagatataa 60 gacactccat tttgatctgt actaagaaaa attgtttctg ctttgagatg ctgttaacct 120 gtaactttag ccccaaccct gtgcttacag aaacatgtgc tgtaatgaat caaagtttaa 180 tggatttagg gctgtgcagg atgtgccttg ttaatagtat gtttgcaggc agtatgcttg 240 gtaaaagtca ttgccatcct ccattctcga ttaaccaggg acataatgca ctgcagaaag 300 ccacagggac ctctgcccaa gaaagcctgg gtattgtcca aggtttcccc tcactaagac 360 agcctgagac atggcctcat gggaagggaa agacctgacc gtccaccagc ccgacaccca 420 taaagggtct gtgctgagga gaagtagtga aagagggagg cctctttgca gttgaggtaa 480 gaggaaggct tctgtctcct gctcgtcctt gggaatggaa tgtctcagtg taaagctgac 540 cattcccatt cgttctattc tgagatagaa gaaaactgcc ctgtggctgg aggtgagata 600 cgctggcagc aatactgctc tgttactctt tgctacactg agatgtttgg gtaaagagaa 660 acataaatct agcctacgtg cacatccagg cacagtacct ttccttgaac ttattcatga 720 tacagattcc tttgctcacg tttccctgct gaccttctcc ccacctgttg ccccactaca 780 ctcccctcgc taagatagtt aaaataatga tcaataaata ctgagggaac tcagaggctg 840 gcaccggtgt gggtcctccg tatgctgagt gccggtcccc tgggcccact gttctttctc 900 tatactttgt ctctgtgtct tatttctttt ctcagtctct caccccacct gatgagaaat 960 atccacaggt gtggaggggc 980 <210> 166 <211> 667 <212> DNA <213> Homo sapiens <400> 166 ttagagttgg tagctaggca gacatgagca gggaaggaga gggctccccc agcaggaata 60 tcaggccacc atcaggtgat ggtcaggtgg ttgttaaact gtctctctaa aataataatt 120 ggttgcacca gggaaaggca gtctcccagt agatagaaaa cacctggagc tggtaatcag 180 cagctttccg ataagatctc aggagttggg tgagtgggct caagcatgtg cactaagagg 240 caaaatggag tttaactggt acatgaccct cctctaggaa cactcaactg gtaagggaaa 300 aacacctcag atgagcatgt gcataacttc agtaaataca ctgtgcaacc cctcccaagt 360 gggcctctct aagcccaccc caagggaaga atcaggggag aagaaacaca aaccccaagt 420 catgccagtg tataaaaccc cacagcaaag gtcggacgag gcacctgaat ctcaagttgc 480 caccctggcc ctcttccaag tgtactttac ttttttttgg tcctgctcta aaatttttta 540 ataaattctc agtcctgctt aaaaactcac cttggtctct cactctgcct tatgcccctc 600 tgacgaattc tctccatcga ggaggcaaga attgagttgc tgcagacctg tatggatttg 660 ccgctgc 667 <210> 167 <211> 809 <212> DNA <213> Homo sapiens <400> 167 tttgcctgca actaaccaat ggaaattact taaaatcctt caccaaacct ttcacttagg 60 cattgatagc acccatcaga tggacaaatt attatttgtt ggaccaggcc ttttcaaaac 120 tatcaagcag atagtcaggt cctgtgaagt gtgccaaaga aataatcccc tgtatgcagg 180 ccatacattt caatctctgt atctttaacc tccttgttaa gtttgtctct tccagaatca 240 aagctataaa actacaaatg gttctccaaa tggagcccca gatgcagtcc atgactaaga 300 tctactgcgg acctctggac cggcctgcta gcccagctcc cacattaatg acatcaaagg 360 cacccctccc gaggaaatct caactgcatg acacctacta cgccccaatt cagcaggaag 420 cagttagagt ggtcgttggc caacctcccc aacagcactt gggttttctg ttgagatggg 480 ggactgagag acaggactag ctggatttcc taggccaact aagaatccct aagcctagct 540 gggaaggtga ctacacccac ctttaaccac taggcttgca acttagctca cacccgacca 600 atcaggtagt aaagagagct tgctaaaatg ctaattaggc aaaaacagga ggtaaagaaa 660 tagccagtca tctatcgcct gacagcacaa ggggcgggac aatgatcagg atataaactc 720 aggcattcaa gccagcaatg gctacccact ttgggtcccc tcccatttta tgggagctct 780 gttttcactc tattaaatct ttcaactac 809 <210> 168 <211> 118 <212> DNA <213> Homo sapiens <400> 168 tgggacaaca gttatcagct caatggcaac agtatataaa agtattgaaa cagctgctta 60 aagctagcgg agccttggtt ttgcaggctc aattaaggga cctaatgcaa actgttgt 118 <210> 169 <211> 2336 <212> DNA <213> Homo sapiens <400> 169 gtcatggccc tcaggcaagc ggactttgga ggctctggaa aagggaaaga ctgggcaaat 60 tgaatgccta atagggcttg ctttcagtgc agtctacaag gacactttaa aaaaaagatt 120 gtctgaatag aaataagccg cccactcatc catgcctctt atgtcaaggg aatcactgga 180 aggcccactg ccccagggga tgaagttcct ctgagtcaga agccactaac cagatgatcc 240 agcaacagga ctgagggtgc ccggggcaag cgccagccca tgccatcacc ctcacagagc 300 cccaggtatg cttgaccatt gagggccagg aggttaactg tctcctggac agtggcgctg 360 ccttctcagt cttactcttc tgtgccagac aactgtcctc ctgatctgtc actatctgag 420 gggtcctagg acaggcagtc actagatact tctcccaggc actaagttgt gactggggaa 480 ctttactctt ttcacgtgct tttctaatta tgcctgaaag ccccactcct ttgttaggga 540 gagacatcct agcaaaagca ggggccatta tacacctgaa tataggagaa ggaacacaca 600 tttcttgtcc cctacttgag gaaggaatta atcctgacaa ttaattcctg acaacagaag 660 gacaatatgg atgagcgaag aatgcccatt cccttcaagt taaactaaaa gattcacctt 720 ctttccctac caaaggcagt acccccttag acctgaggcc caacaagtac ttcaaaagat 780 taaggaccta aaagcccaag gcctagtaaa atcatgcaat agtgcaatag tccctacaat 840 acttcaattt taggagtaca gaaacccaat ggagagtgga gattagtgca agatctcagg 900 attatcaatg aggctgctgt ccctgtataa ccagctgcac ctaaccctta tgctctgctt 960 tcccaaatac cagaagaagc agaatggttt acagtcctgg accttaagga tgactttttc 1020 tgcatccctt acatcctgac tctcaattct tctttgcctt tgaagatcct tcgaacccaa 1080 cgtctcaact cacctggact gttttacccc aaggtttcag gccatctatt tggccaagca 1140 ttagcccaag acttgagcca gttctcatac ttggacactc tcgtcctttg gtatgtgaat 1200 gatttacttt tagcctcctg ttcagaaact ttgtgccatc aagccaccca agcgctctta 1260 aacttcctca ccacttgtgg ctacaaggtt tccaaaccaa aggctcagct ctgctcacag 1320 cagtttaaat acttagggct aaaattatcc aaaggaacca gggccctcag tgaggaatgt 1380 aaccagccta tactggctta tcctcatccc acaacgctgg atactgccaa aggaacctga 1440 aaatgcagga gacaatgcta gctattcctg cgaacctcta caggatctgt gcctgctctt 1500 caaatgacaa ccgtgaggaa agtaactaga atcgtagatc cccgtggccc tcccttgtca 1560 catttttctc tttactgttc tcttacccac tttcactctc attgcacctc ctccatgctg 1620 ctgtactacc agtagttccc ctcaccaaga gcttctatgg ataatgcagc ttcccagaaa 1680 tactgacacc tcattgtata ggagtttttc taaaggaaac cccactttca ccccccgtac 1740 acatactcgc ccagtaagcc tatttaatac cactctcact gggctccatg aagcctcagc 1800 ccaaaaccct actaactgtt ggatgtgcct caccctgcat ttaggccata catttcaatc 1860 cctgtatctt taatctcctt gttaagtttg tctcttccag aatcgaaggt gtaaaactac 1920 aaatcgttct tcaaatggag ccccagatgc agtccatgac taagatctac tgcggacccc 1980 tggactggcc tgctagccaa tgctctgatg ttgatgacat cgagggcacc tctcccaagg 2040 aaatctcaac tgcatgaccc ctgctatgcc ccaattcagc agaaagcagt tagagcagtc 2100 gtcagccaac ctccccaaca gcacttgggt tttcctgttg agagagggga ctgagagaca 2160 ggactagctg gatttcctag gccgactaag aattcctgaa cctagctggg gaagctgacc 2220 acacccacct ttaaacacag ggcttgtaac tcagctcaca cctgaccaat caggttgtaa 2280 agagagccca gtaaaatacc aattaggcta aaagcaggag gtaaagaaat aatcaa 2336 <210> 170 <211> 312 <212> DNA <213> Homo sapiens <400> 170 tgggtcaggc acaaagtaag cccaccccac taggaactat gttgaaaaat ttcaagaaag 60 gatttaaggg agattacagt ggtactatga caccaggaaa acttagaact ttgtgtgaca 120 tagactggcc agcattagag gtgggttggc catcagaagg aagcctggac aggtcccttg 180 ttacaaaggt atggcacaag gtaacctgta agccagggcc cccagaccag ttcccgtaca 240 tagacacttg gttacaactg gttttagacc ctcccgcccc acacagtggt tgagagaaca 300 gcagcataag tg 312 <210> 171 <211> 1154 <212> DNA <213> Homo sapiens <400> 171 agttttgcct gacaaaggtc tcttcttcct ccgtggctcc tccacctaca tgtgtctgcg 60 tatgaattgg acaggcacat gaacactagt tttccttact cccaaaaatc tgtttgcaaa 120 taggaccaaa cagctttctg ttcccctcat gacaccaata cttcatcact attttgtctt 180 atttttctta ttaatataag atgacaggaa taggcctcaa cttactcgct gctgaaaaag 240 gaggactgta tatattttta aatgaagagt gttgttttta cctaagtcaa tcttgcctgg 300 tatatgacaa cataaaaaac tcaacgatag agcccaaaaa cttgccaacc aggcaaataa 360 ttatgctaaa cctccctggg cactttctaa ttggatttcc cggctcctcc caattcttag 420 tcctctacta cctgtttttc tccttctctt atttggacct tgtgccttcc atttagtttc 480 tcaattcata caaaaccgca tccaggccat caccaatcat tctatatgac aaatactcct 540 tctaacagcc ccaccatatc accccttacc acaaaacctt ccttctgttt aatctctccc 600 actgtaggtt cccacgccgc ccctaatccc gctcgaagca gccctgagaa acattgccca 660 ttatctctct ataccacctc caaaaatttt caacgcccca acactccacc actatttttt 720 gtttttctta ttaatataaa aagacaggaa tgtcaggtct ctgagcccaa gctaagccat 780 cataacccct gtgacctgca tgtatacatc cagatggcct ggagcaactg aagaaccaca 840 aaagatggca ttccaccatt gtgatttgtt cctgccccac tctaactaat catttgacct 900 tgtgacattc cccacctgga caatgagtct catgatcttc ccaccctgca ccttgtgacc 960 cctgcccctg cccaaaagag ataaccacct ttaactgtac ttttccacta cctacccaaa 1020 tcctataaaa ctgccccacc cctatctccc tttgctgact cctttttggg actcagtacg 1080 cctgcaccca ggtgattaaa aagctttatt gcgcacacaa agcctgtttg gtggtctctt 1140 cataaggatg catg 1154 <210> 172 <211> 972 <212> DNA <213> Homo sapiens <400> 172 gtggggaaaa gaaagagaga tcagattgtt actgtgtctg tgtaggaaga agtagacata 60 agagactcca ttttgttctg tactaagaaa aattcttttg ccttgagacg ctgttaatct 120 gtaaccctac ccccaaccct gtgctcccta agacatgggc tgtgtcaact cagggttaaa 180 tggattaagg gctgttcagg gtgtgctttg ttaaacaaat gcttgaaggc agcatgcttg 240 ttaagagtca tcaccactcc ctaatctcaa gtacccagag acacactaca ctgcggaaga 300 ctgcagggac ctctgcctag gaaagccagg tattgtccaa ggtttctccc catgtcatag 360 tctgaaatac agcctcatgg gaagggaaag acctgactgt cccccagccc gacacccgta 420 aagggtctgt gctgaggagg attagtaaaa gaggaaggaa ggcctctttg cagttgagat 480 aagaggaagg catctgtctc ctgctcatcc ctgggcaatg gaatgtctcg gtgtaaagcc 540 cgattgtata ttccatctac tgagatagga gaaaaccgcc ttaggactgg aggtgggaca 600 tgctggcagc aatactgctc tttaaggcat tgagatgttt atgtatatgc acatcaaaag 660 cacagcactt ttttctttac cttgtttatg atgcagagac atttgttcac gtgtttacct 720 gctgatcttc tctccactat tatcctattg tcctgccaca tccccctctc cggaaacgcc 780 caataatgat caataaatac taagggaact cagaggccag tgcaggcatg ggtcctccgt 840 atgctgaacg ccagtcccct gggcccattt ttctttctct gtactttgtc tctgtgtctc 900 tttcttttcc aagtctctcc ttccacctaa cgagaaacgc ccacaggtgt ggaggggcaa 960 cccatccctt ca 972 <210> 173 <211> 682 <212> DNA <213> Homo sapiens <400> 173 ttagagttgg tatttaggca gacatgagca gggcagaaga gggccccctg ccccagggat 60 gtcaggtgac catcaggtga tagccaggtt gttgttaagc tgtctctaat tggccatgcc 120 tggcactagg gaaaggctgt cttccagtag acaggaaaca tctgaagctg gtgatcagct 180 tcctgatagg atctcaggag ctggatgagt gggcccaagt atgtgcacta aatggcaaaa 240 tggcagagtt taactggtat gtgaccttcc tctaggaatg cttacctgga aagggtaatg 300 atcttgcaca caatttcagc aaacacactg tgcatgctcc tctcccaagt gctggcaggc 360 cactgcatgg gagcagcctg ctgcaaggga agaatcaggg aagaagaaat gtggaccctg 420 gagtcatgtc atacaagacc ccacccaagt cgagggtcag acagagcact tgaatctctc 480 aagtcgcctg cttggccctt tccaactgta ctttactccc tttcattcct tctctaaaac 540 tttttagtaa acttttactc ctgctctaaa acttgcctca gtctctcacc ctgcctgctg 600 ccccttggct gtattctttc ttctgcaagg caagaattga gttgctgcag acttgtacag 660 atccacccct gctaacaaga ct 682 <210> 174 <211> 680 <212> DNA <213> Homo sapiens <400> 174 ttagagtagg tagttaggca gacatgagcc aggcaggaga gcctctccca accccagaga 60 acttcagggg accatcaggt aatggtcagg tggttgttaa actgtgtctc tgaaattata 120 attggtcaca gctggtacta gggaccgaca gtctcccaat aaataggaaa ctcctggagc 180 tgtggaggag cagcagcttc ccgataagat ctcagggatt gggctagtgg gctcaagcat 240 gcactaagag gcaaaatggc aaagtttaac tggtatataa ccttcctctg ggaatttttg 300 tctaatgagg ggaaaaacac ctcaagtgag catgcacaca acttcagtaa acacactgtg 360 tatgcacccc ttcccaagtg ctggcgggcc actgtgcctg tggacagcct gccgcaaggg 420 agaaatcaag ggaggagaaa ctcaaatccc ggaaccaagc caatgtatta aaatcccaag 480 ccaaaggttg gacggggcac ttggatctct caaggaaccc acttgaccct cttccaagtg 540 tgctttgctt cctttcactc aggctctaaa actttttaat aaactctcac ttttgctcta 600 aaacttgcct cagtctctcc ctctgcctta aacatacttc tgcccctcag ccaaattctg 660 tcctccagag aggcaaggat 680 <210> 175 <211> 972 <212> DNA <213> Homo sapiens <400> 175 gtggggaaaa gaaagagaaa tccgactgtt actgtgtcta tgtagaaaga agtagacata 60 agagactcca ttttattctg tactaagaaa aattcttctg ccttgagatg ctgttaatct 120 gtaaccctac ccccaaccct gtgctccctg aaacatgtgc tgtgtcaact cagggttaaa 180 tggattaagg gctgtgcagg atatgctttg ttaaacaaat gcttgaaagc agcatgcttg 240 ttaagagtca tcaccactcc ctaatctcaa gtacccagaa acacagtaca ctgaggaagt 300 ccgcagggac ctctgtctag gaaagccagg tattgtccaa ggtttctccc catgtgacag 360 tctgaatatg gcctcctggg aagggaaaga cctgaccatc ccccagcctg acaaccgtaa 420 agggtctgtg ctgaggagga ttagtaaaag aggaaggaag gcctctttgc agttgagata 480 agaggaaggc atctgtctcc tgctcatccc tgagcaatgg aatgccttag tgtaaaaccc 540 cattgtatat tccatctact gagatgggga aaactgcctt agggctggag gtgggacatg 600 ctggcagcaa tactgctctt taaggcattg agatgtttat gtatatgcac atcaaaagca 660 cagcactttt ttctttacct tgtttatgat gcagagacat ttgttcacat gttttcctga 720 tgaccttctc cccactatta ccctattgtc ctgccacatc cgcctctcca agaaatgccc 780 gataatgatc aataaatact aaaggaactc agagactggt gccggcgcgg gtcctccata 840 tgctgagcgc cagttccctg ggcccacttt tctttctcta tactttgtct ctgtgtctct 900 ttcttttctt aagtctctca tcccatccga tgagaaacgc ccacaagtgt ggaggggcag 960 gccacccctt ca 972 <210> 176 <211> 5754 <212> DNA <213> Homo sapiens <400> 176 acttggagga ctgtgggtat taggtgtcca agaagaaagc tcaaatctgc tgacggcagg 60 taccttactt gggatttact ctccgacagg ggtccgaact cagcccggga acagaaagaa 120 agcaggttat ttgcaatcta ccggagccta agggcagaag gcaggtgagg gaattcttgg 180 gagctgtggg gttttgtaga ctgtgcatcc caaactttgc agtattagcc aagccctttt 240 atgaggtcac aaagggggcg gggaccggga acctttggaa gggggatccc aacaacagca 300 agtctttcat gagttaaagg aaaaacttcc ggcagccgca gccctgggat aaccgatctg 360 acaaagcctt ttccattgaa tgcatcagag agaaaataga tggcagctgg acatttaacc 420 caaagtgtgg agccctggct gaggccggtg gcctacgtct ctaaacaact agacaggttt 480 tctaaaggat ggcccccctg tttgagggca gtggcagcaa ctaccctgct agtagaagac 540 gcaaataagc tgactcttgg gcaaaacctg aacataaagg ccccccattt tgcggtgggt 600 gagagccagc ccttcttacc cccttgcctc tcaggacccc catcgcaggg cgggaggcac 660 ctcccatgag gcggggactg agaggcagcc cctcttcccc ccttggctct tgggaacccc 720 atcgcagggt ggggaggcaa cccccgtgat gaagggaaaa aaagagccag cccctcttcc 780 ccccctggct cttaggacca ccatcgcagg aaggggaggc aacccccacg ggggagggac 840 tgacagccat cccctcttct cccctggctc ttaggacccc cattgcaggg ggggggaggc 900 accctccgag aggcggggac tgagagccag cccctcttcc agctctggct taggaccccc 960 atcgcggatc ctatgtacct taggaccctc ctggaggact gtgggtatag gtgtccaaga 1020 agaaagctca aatctgccga aggcaggtac cttacttggg atttactgtc caacaggtgt 1080 cagaacgcag cccgggaaca gaaagtaagc aggtcatttg caatctacca gagcctaggg 1140 gcggaaggaa ggtgaggaaa ttcttagggg ctgtggggtt ttgtagactg tgcatcccaa 1200 actttgcagt attagccaag cctttgtatg aggtcacaaa aggggcgagg accaggaacc 1260 tatggaatcg ggatcccaac aacagcaagt ctttcatgag ttaaaggaaa aacttctggc 1320 agccccagcc ctgggtctac ccgatctgac aatgtctttt ccattgaatg cgtcagatag 1380 agaaaagatg gcagctggac ttttaatcca aactctgggg ccctggctga ggccggtggc 1440 ctacgtctct aaacaactaa aaagggtttc taaaggatgg cccccctgtt tgagggccgt 1500 ggcagcaact gccctgatag tagaagaagc aaataagctg actcttgggc aaaacctgaa 1560 cataaaggct gcccattttg gggtgggtga gagccagccc ctcatccctc cctgccttag 1620 gacccccatc gcgcatccta agatccttag gacccacctg gaggactgtg ggtattaggt 1680 gtccaagaag aaagctcaaa tctgccgacg gcgggtacct taattgggat tgactatccg 1740 acaggggtcc cacgccgccc gggaacagaa agaaagcagg ttatttgcaa tctaccagag 1800 cctaagggtc gaaagcaggc gagagaattc tcaggagctg tggggttttg tagactgtgg 1860 atcccaaact ttgcagtata agccaagcct ttgtatgagg tcacaaaggg ggcggggacc 1920 gggaaccttt ggaatgggga tcccaacaac agcaagtctt tcatgagtta aaggaaaaac 1980 ttctggcagc ttcagccctg gggctaccca atctgacaaa gccttttaga ttgtacacgt 2040 cagagagaga caagatggcg ggtggacttt taacccaaac tgtggggccc tggaagaggc 2100 cggtggccta cgtctctaaa caactagaca gggtttctaa aggatggcac cctgtttggg 2160 ggccttggca gcaactgccc tgctagtaca agaagaaaat aagctgactc ttgggcaaaa 2220 cctgaacata aaggcccccc gttttgtggt ggctgagagc cagcccctct tcccccactg 2280 gctcttggga cccccatcgc gttggggggg aggcaccctc cgcgaggcgg ggactgagag 2340 ccagcccctc ttccccccct ggctcttggg acccccatcc caggggggga ggcaccccca 2400 cgaggcgggg actgagagcc agcccctcat ccccccttgg ttcttgggaa ccccatcgca 2460 gggggggatg caacccccgc gacgagagga cagagagcca gcccctcttc acccctggct 2520 cttaggaccc acatcgcacc tgagggaggc acccccgcga ggcggggact gacagccccc 2580 tcttcccccc cagactcttg ggatcaccat cgcaggggcg ggaggcacac cccgcgaggc 2640 ggggactgac agccagcccc tcttcccccc ctggctctta ggacacccac cgcagagggg 2700 gggaggcacc ccccgccagg caggaactga gagccagcac ctcttccccc gctggctctt 2760 aggaccccca tcgcagagcg ggaggcaccg cccatgaggc agggactgag aaccagcccc 2820 tcttcccccc tggctcttag gacccccatc gcagtagggg gaggcagccc ccgcgagccg 2880 aggattgaga gccagcccgt attccccccc tgacacttgg gacccccatc gcagggtggg 2940 aaggcacccc ccgcgaggcg ggtactgaca gccaggccct cttccccccc gaatcttggg 3000 acccccatcg cagtggggga ggcacccccg cgaagcgggg actgagagcc agcccctttc 3060 cccccttggc tcttgggacg gccatctcaa gaggggggat gcaaaccctg caacgagggg 3120 acagagagac agcccttctt caccccctgg ctcttaggac ccccatcgca cctggggagg 3180 gcacccccgc gaggcgggga ctgagagcca gcccgtcttc cacccctggc tcttcggaaa 3240 cccatggcag cggggcgagg cagcccccac gaggcgggga ctgagttcca gcccctcttc 3300 accacctggc tcttaggacc accatctcag aggcgggagg caccacccgc gaggtgggga 3360 ctgagagcca gccactcttc ccccgctggc ttaggacacc catcgtggat cctaagaacc 3420 ttaggaccca cctggaggac tgtgggtatt aggtgtccag gcagaaagct caaatctgcc 3480 gacggcaggt accttacttg ggatttacta tcggacgggg tccgacgcct ccctggaaca 3540 gaaagaaagc aggttatttg caatctacca gagcctaagg gccgaaggca ggcgagagaa 3600 ttctcaggag ctgtggggtt ttgtagactg tggatcccaa actttgcagt ataagccaag 3660 agtttgtatg atgtcacaaa gggggcgagg actgagaacc tttggaaggg ggatcccaac 3720 aacagcaagt ctttcatgag ttaaaggaaa aacttctggc agcttcagcc ctggggctac 3780 ccgatctgac aaaacctttt ccattgtatg cgtcagagag acaagatggc aggtggactt 3840 ttaacccaaa ctattgggcc ctggatgagg ccggtggcct acttctctaa acaactagac 3900 agggtttcta aaggatggcc ccctgattga gggccttggc agcaactgcc ctgctagtac 3960 aagaagcaaa taagctgact cttgggcaaa acctgaacat aaagtccccc cattttgtag 4020 tggctgagag ccagcccctc ttccccccct ggctcttggg accccatcac gtgggggggg 4080 aggcaccctc cgcgaggcgg ggactgagag ccagcccctc ttcccccctg gctcttagga 4140 ctcccatcac agtgggggga ggcagccccc gcgagccgag gactgagagc cagcacctat 4200 acccccctga cacttgggac ccccatcgca gggtgaggag gcaccccccg cgaggcgggg 4260 actgagagct agcccctctt cacccctggc tcttaggacc cacatcgcac ctgtgggagg 4320 cacccccacg aggcggggac tgagagacag cccctcttcc cccccagact cttaggatcc 4380 ccatcccgga gagggaggca caccccgcga ggcagggact gagagccagc acctggtccc 4440 ccccctggct taggaccccc atcgtggatc ctatgaactt taggacacac ctggaggact 4500 gtgggtatag gtgttcaaga agaaagctca aatctgccga tggcaggtac cttacttggg 4560 atttactatc cgacaggggt ccgaacgcac ccgggaacag aaagaaagca ggacatttgc 4620 aatctaccgc agcctaaggg cagaaagcat gtgagggaat tcttaggggc tgtgggattt 4680 tgtagactgt gcatcccaaa ctttgcagta ttagccaaga ctttgtatga gatcgcaaag 4740 tgggcgggga ccgggaacct atggaatcgg gatcccaaca acagcaagtc tttcttgagt 4800 taaaggaaaa acttctggca gccccagccc tggggctacc tgatctgaca aagccttttc 4860 cattgaatgc atcagataga gaaaacatgg cagccggact tttaactcaa actgtggggc 4920 cctggatgag gccagtggcc tacgtctcta aacacctaga cagggtatct aaaggatggc 4980 ccccctgttt gagggccatg gcagcaactg ccctgatagt agaagaagca aataagctga 5040 ctcttgggca aaacctgaac ataaaggcca cccattttgg ggtgggtgag agccagcccc 5100 tcttcccccc ctgccttagg acccccattg cagatactaa gatctttagg acacacctgg 5160 aggactgtgg gtattaggtg tccaagaaga aagctcaaat ctgcctaggg caggtaactt 5220 acttgggatt tccgatccga caggggtccg aagccacccg ggaacagaaa gaaagcatgt 5280 tatttgcaat ctaccagagc ctaagggcca aaggcaggcg agagaattct caggagctgt 5340 ggggttttgt agactgtgga tcccaaactt tgcaatataa gccaagcctt tgtatgaggt 5400 cacaaagggg gcggggaccg ggaacctttg gaatggggat cctaacaaca gcaagtcttt 5460 catgagttaa aggaaaaact tctggcagct tcagccctgg ggttacccga tctgacaaaa 5520 ccttttccat tgtatgcgtc agagagagaa aagatggcag gtggactttt aacccaaact 5580 gtggggcctt ggatgaggcc ggtggcctat gtctctgaac aactagacag ggtttctaaa 5640 ggatggcccc cctgtttgag ggccttggca gcaactcccc tgctagtaca agaagcaaat 5700 gagctgactc ttgggcaaaa cctgaacata aaggcccccc attttgtggt ggct 5754 <210> 177 <211> 316 <212> DNA <213> Homo sapiens <400> 177 gagagacagg actagctgga tttccaaggc cgactaagaa tccctaagtc tagctgggaa 60 ggtgactgca tccaccttta aacatggggc tttcaactta gctcacaccc gaccaatcag 120 gtagtaaaga gagctcacta aaatgctact aattaggcaa aagcaggagg taaagaaata 180 gccaatcatc aaatgcctga gagcacaggg ggagggacaa tgattgggat ataaacccag 240 gcattcaagc aggcaatggc agccccgtgt gggtcccctc ccattgtatg ggagctctgt 300 tttcactgta ttacac 316 <210> 178 <211> 5971 <212> DNA <213> Homo sapiens <400> 178 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tcacttgcac gtacacaccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa tatgccctgc ctcacctcaa 120 ctgatgacat tccaccacaa aagaagtgaa aatggcctgt tcctgcctta actgatgaca 180 ttgtcttgtg aaattccttt tcctggctca tcctggctca aaaacctccc ccactgagca 240 ccttgcaacc cctacgcctg ctcgccagag aacaaaaccc ctttgactgt aattttcctt 300 tacctaccca aatattataa aacggcccca cccctatctc cctttgctga ctctcttttc 360 ggactcagcc cgcaggcacc caggtgatta aaagctgtat tgctcacaca aagcctgttt 420 ggtggtctct tcacacggac gcgcatgaaa tttggtgccg tgactcagat cgggggacct 480 cccttgggag atcaatcccc tgtcctcctg ttctttgctc cgtgaaaaag atccacctac 540 gacctcaggt cctcagaccc accagcccaa ggaacatctc accaatttta aatcgagtaa 600 gcggcctctt cttactctct tcttcaacct ctctcactat ccctcaacca ctttctcctt 660 tccactcttc aatctctccc ttctttcaat ttcaattcct ttcattttct ggtagagaca 720 aaggagacat gttttatccg tggacccaaa accccggcgc cggtcacaga ctgggaaggc 780 agccttccct tggtgtttaa taattgcaga tacgcctctc tgattattca cccacgtttc 840 agaggtgtca gatcacgcag ggacgcctgc cttggtcctt cacccttagc ggcaagtccc 900 acttttctgg ggggggcaag taccccaacc ccttctctct gtgtctctac cccgtctcca 960 cctttctggg gggcaagaaa cccctaaccc ttctccttca ctcttagcag caagtcccgc 1020 ttttctagag gaggggcaag taccccaacc ccttctctcc atgtctctac ctcttctccg 1080 cctttctggg gggcaagaaa ctcccaaccc cttctccttc atccttagcg gcaagtcctg 1140 cttttctggg ggaggggcaa gtaccccaac cttgtatctc tgcgccccga tcccttatgt 1200 ccatgccccg acctcttata tctctgtgct ccgatccctt atttccacgc cccaacctgt 1260 tatatctctg cgccctgatc ccttatttcc atgccccgac cttgtatctc tgcgccccga 1320 cccctttccc acttttctgg agggtaagaa cccctgaacc ccttccctcc tgtctctatc 1380 ttttctctgg gcttgcttcc ttcactatgg gcaaccttcc accctccatt cctccttctt 1440 ctcccttagc ctgtgttctc aaaaacttaa aacctcttca actcacatct gacctaaaac 1500 ctaaatgcct tactttcttc tgcaatgcca cttgacccca atacaaactc aacagtggta 1560 ccaaatagcc agaaaatggc actttcaatt tttccatcct acaagatata aataattctt 1620 gtcgtaaaat aggcaaacgg tctgaggtgc ctgacgtcca ggcattcttt tacacatcag 1680 tcccttccta gtctctgttc ccaatgcaac tcgtcccaaa tcttccttct ttccctcccg 1740 cctgtcccct cagtcccaac cccaagcatc actgagtctc caatcttcct tttctacaga 1800 tctatctgac ctctcccctc ctcgccaggc cgagctaagt cccaattctt cctcagcccc 1860 ctcttctcca ccctataatc cttttatcac ctcccctcct gacacccggt ctggcttaca 1920 gtttcattcc gtaactagcc ctctgccacc tgcctagcaa tttactctta aaaaggtggc 1980 tggagctaaa gacatagtca aggttaatgc tcctttttct ttatcccaaa tcagatagcg 2040 tttaggctct ttttcatcaa atataaaaat ccagcccagt tcatgactcg tttggcagca 2100 accctgagac tctttacagc cctagaccct aaaacatcaa aaggctgtct tattctcaaa 2160 atacatttta ttacccaatc tgctcccaac attaaataaa actccaaaaa ttaaattctg 2220 gccctcaaac cccacaacgg gattaattaa cctcgccttc aaggtgtaca ataatagaaa 2280 aaagttgcaa ttccttgcct ccactgtgag acaaacccca gccacaactc cagcacacaa 2340 gaacttccaa atgcctgaac cgcagcggcc aggcgttcct ccagaacctc ctctgccagg 2400 agcttgctac aagtgccaga aatctggcca ccaggccaag gaatgcctgc agcccaggat 2460 tcctcctaag tcacgtccca tctgtgcagg accccactgg aaatcggact gtccaactca 2520 cctggcagcc actcccagag cccctggaac tctggcccaa ggctctctga ctgcttccca 2580 gatcttcttg gcttagcggc tgaagactga cactgcctga tcacctcgga agccccctag 2640 accatcacgg actccgagct tcgggtaacc ttcacagtgg aaggtaagtc cgtccccttc 2700 ttaatgaata cggaggctac ccactccaca ttacctcctt ttcaagggcc tgtttccctt 2760 gcctccataa ctgttgtggg tattgacggc caggtttcta aacctcttaa aactccccaa 2820 ctctggtgcc accttagaca atactctttt aagcactcct ttttagttat ccccacctgc 2880 ccagttccct tattaggcca agacacttta actaaattat ctgcttccct gactattcct 2940 gggctacagc cacatctcat tgccaccttt tcccccactt caaagcctcc ttcacatcct 3000 cctcttgtat ccccccacct taacccacaa gtataggata cttctactcc cttcttggtg 3060 accgatcatg caacccttac catctcatta aaatctaatc acccttaccc cactcaacgc 3120 cagtatccca tcccacagca cgctttaaaa agattaaagc ctgttatcac tcgcctgcta 3180 cagcatggcc ttttaaagcc tataaactct ccttacaatt cccccatttt acctgtccta 3240 aaaccagaca agccttacaa gttagttcag gatctgtgcc ttatcaacca aattgttttg 3300 cctatccacc ccatggtgct gaacccatat actctcctat cctcaatacc tccctctaca 3360 acccattatt ctgttctaga tctcaaacac gctttcttta ctattccttt gcacccttca 3420 tcccagcctc tcttcgcttt cacttggact gaccctgaca cccatcacgc tcagcaaatt 3480 acctgggctg tactgccgca aggcttaaca gacatccccc attacttcag tcaagcccaa 3540 atttcttcct catctgttac ctgtctcggc gtaattctta gaaaaacaca tgtgctctct 3600 ctgccgatcg tgtctgactg atctctcaaa ccccaacacc ttctacatcc taggcatggt 3660 tagatacttt cgactttaga tacctggttt tgccatccta acaaaaccat tatataaact 3720 cacaaaaaga aacctagctg accccataga tcctaaatcc tttccccact cctttttccg 3780 ttccttgaag acagctttag agactgcccc aacccgagcg ctccctgact catcccaacc 3840 cttttcatta cacagagctg aagtgcaggg ctgtgcagtc ggaattctta cacaaggacc 3900 gggatcgcgt cctgtagcct ttttgtccaa acaacttgac cttactgttt taggctggcc 3960 atcatgtctc cgtgcagtgg ctgctgccac cccaatactt tcagaggccc ttaaaatcac 4020 aaactatgct caactcactc tctacagctc tcataatttc caaaatctat tttcttcctc 4080 acacctgatg cctatacttt ctgctcccca gctccttcat ctctctgatc cacctgacgt 4140 tcaccccatt tccccacatt tccttctccc ctgtttctca ccctgatcac acttagttta 4200 ttgatggcag ttccaccagg cgtaatcgcc acacaccagc aaaggcaggc tatgctatag 4260 tacaagccac tagcccgcct cttagaacct ctcatttcct ttccattgtg gaaatctatc 4320 ctcgaggaaa taacttctca gtattccatc tgctatgcta ctactcctca gggattattc 4380 aggccccctc tcttccctac acatcaagtt cagggatttg cccccgccca ggactggcaa 4440 attagcttta ctcaacatgc cccgagtcag gaaactaaaa tacctcttat tctaagtaga 4500 cactttcact gaataagtaa aggcctttcc tacagggtct gagaaggcca ccgtagtcat 4560 ttcctccctt ctgtcagaca taattcctta gtttagcctt cccacctcta tacagtctga 4620 taacagacca gcctttatta gtcaaatcag ccaagtagtt tttcaggctc ttagtattca 4680 gtgaaacctt tacatccctt acagtcctct gtcttcagga aaagtagaac agactaaagg 4740 tcttttaaaa acacacctca ccaagctcag ccaccaactt aaaaaggact ggacaatact 4800 tttaccactt tcccttctca gaagtcagac ctgtcctcag aatgctacag ggtacagccc 4860 atttgagctc ctgtatagac gctccttttt attaggcccc agtctcattc cagacaccag 4920 accaacttag actgtgcccc aaaaaaactt gtcatcccta ctatcttctg tctagtcata 4980 ctcctattca ccattctcag ctactcatac atgccctgct cttgtttaca ctgccggttt 5040 acactgtttc tccaagccat cacagctgat atctcctggt gctatcccca aactgccact 5100 cttaactctt gaagtaaata aataatcttt gctggcagga ctatgctgaa tctccttagg 5160 cactctctaa tcagatgtcc tgggtcctcc caattcttag accttttata cctgtttttc 5220 tccttctctt attccattta gtttttcaat tcatacaaaa ccatatccag gccatcacca 5280 atcattctat acaacaaatg tttcttctaa caaccccaca atatcacccc ttaccacaaa 5340 atcttccttc agcttaatct ctcccactct aggttcccaa gccaccccaa tcctgctcga 5400 agcagccctg agaaacatcg cccattctct ctctccatac caccccccaa aaattttcgc 5460 caccccaaca cttcaacact attttgtttt atttttctta ttaatataag aaggcaggaa 5520 tgtcaggcct ctgagcccaa gccaagccat cgcatcccct gtgacttgca catattcgcc 5580 cagatggcct gaagtaactg aagaatcaca aaagaagtga atatgccctg ccccgcctta 5640 actgatgaca ttccaccaca aaagaagtga aaatggcctg ttcctgcctt aactgatgac 5700 attgtcttgt gaaattcctt ttcctggctc atcctggctc aaaaacctcc cccactgagc 5760 accttgcaac ccccactcct gcccgccaga gaacaaaccc cctttgactg tcattttcct 5820 ttacctaccc aaatcttata aaacggcccc acccctatct ccctttgctg actctctttt 5880 cagacttagc ccgcctgcac ccaggtgatt aaaagctgta ttgctcacac aaagcctgtt 5940 tggtggtctc ttcacacgga cgcgcatgaa a 5971 <210> 179 <211> 6101 <212> DNA <213> Homo sapiens <400> 179 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcat gtatacatcc 60 agatggcctg aagcaactga agatccacaa aagaactgaa aacagcctta actgatgaca 120 ttccaccatt gtgatttgtt cctgccccac cctaagtgat aggctatgtt ctcccccgcc 180 cttaagaagg tactttgtaa tattctcccc cgcccttaag aatgtacttt gtacacctat 240 cccaaacgta taaaaactaa tgataatccc accaaccttt gctgactcct ttctcggact 300 cagcccacct gcacccaggt gaaataaaca gccctgttgc tcacacaaag cctgttggtg 360 gtctcttcac aaggatgcgt gtgacatttg gtgccaaaac ccaggacagg aggactcctt 420 caggagacca gtcccctgtc ttcgccctca ctccgtgacc tcaggtcctc agaccaacca 480 gcccaaggaa catctcacca acttcaaatt gggtaagcag tcttttcact cttctcatgc 540 ctctcttgct acccttcaat cttcctctct tgctaccctt caatctccct gtccttccaa 600 ttccaattct ttttcctctc tagtagagac aaggagacgg ccaggtgcgg tggctcacgc 660 ctgcaatccc agctctcagg gaggctaaga ggcgggagga tagcttgagc ccaggagttc 720 gagacctgcc tgggcaatat agcgagaccc cgttctccag aaaaaggaaa aaaaaaaaaa 780 aagagacaag gagacacatt ttatccgtgg acccaaaact ctggcgccag tcacggactc 840 gggaagatag tcttcccttg gtgtttaatc actgcggaga tgcctgcctg attattcacc 900 caccctccac tggtgtctga tcactgcggg gacacctgcc ttagtcattc acccacattc 960 ccttggtggc aagtcaattg cagggatgcc tgctttggct gctcacccac attgcagccc 1020 agggctgctc acccacccac ttctccatgt ctctaccttt ctctttaaac ttacctcctt 1080 cactatgggc aaccttccac tcgccattct cccttcttct cctttagcct gtgttctcaa 1140 aaacttaaaa cctcttcaac tcacacctga cctaaaacct aagcgtctta ttttcttcta 1200 caacaccgct tggccccaat acaaacttga caatgattcc aaatagccag aaaatgacac 1260 tttcgatttc tccatcctac aagatctaga taattcttgt cataaaatgg gcaaatggtc 1320 tgaggtgcct gacgtccagg cattctttta cacatcggtc ccttcctaat ctctgttccc 1380 aatgagattc atcccaaagc tttcttcttt ctctcctgtc tgttccttca gtctccaccc 1440 caagctctga atcctgggaa tcctcctttt ctacagaccc atctgacctc taccctcctc 1500 cccaggctgc tccttgccag gccgagccag ctcccaactc ttcttcaacc tctgctcccc 1560 caccctataa cccttctatt acctcccctc ctcacacccg gtctggctta cagtttcatt 1620 ccgtgaccag ccctccccca cctgcccaac aatttcctct cagagaggtg gctggagctg 1680 aaggcatagc caaggttaat cctccttttt ctttatccaa cctctcccaa atcagttagc 1740 gtttaggctc tttttcatca aatatgaaaa cccagcccag tccatggccc gtttggcaac 1800 aacccttaga tgctttaccg ccctagaccc agaggggcca gaaggctgtc ttattctcaa 1860 tacacatttt attacccaac ccactcctga cattagaaaa atctccaaaa attagattct 1920 ggccttcaac cccccaacag tacttaattg acctcacctt caaggggtac agtaatacag 1980 aagagttgta attacttgcc tccgctgtga gagaaacccc agctacatct ccagcacaca 2040 agaacttcaa aacgcctaaa cctcaggggt caggcattcc tccaggaccg cctccccagg 2100 atcttgcttc tagtgctgga aatctggcca ctgggccaag gaatgcctgc agcctgggat 2160 tcctcctaag ccgtgtccca tctgtgcagg accccactgg aaatcagact gtccaactca 2220 cccagcagcc actcccagag cccctggaac tctggcccaa ggctctctga ctgactcctt 2280 cccagatcgt ctcagcttag cggctgaaga ctgacactgc ccgatcgcct cggaagccta 2340 caggaccatc acagatgctc tggataactc ttacagtgga gggtaagtcc atcctcttct 2400 ttatcaatac ggaagctaca cactccacat taccttcttt ccaagggcgt gtttcccttg 2460 cctccataac tgttgtgggt attgacagcc aggcgtctaa acctcctaaa actccccaac 2520 tctggtgcca acttggaaaa cattctttta tgcactcctt tttagttatc ctcacctgcc 2580 cagctccctt attaggttga gacattttaa ctaaattttc tgcttccctg actattcctg 2640 ggctacagcc acacctcatt gcctcctttt cccccagttc aaagcctcct tcacatcctc 2700 tccttgtatc tccccacctt aatccacaag tataggacac ctctactccc tccttggcaa 2760 cggatgatgc accccttacc atcccattaa aacctaatca cccttaccct gctcaatgcc 2820 aatatcccat cccacagcac gctttaaaag gattaaagcc tgttatcact cacctgctac 2880 agcatggcct tttaaagcct ataaactctc cttacaattc cccattttac ctgtccaaaa 2940 actacacgag tcttacaggt tagttcagga tctgcaccct atcgaccaaa ttgtcttgcc 3000 tatccaccct gtggtgccaa agccatatat tctcccatcc tcaatacctc cctccacaac 3060 ccattattct gttctagata aacctagctg accccataaa tcctaaatcc tttccccact 3120 cccctttcca ttccttaaaa aacagcccta aaagatgctc ccacactacc tctccctaac 3180 tcatcccaac ctttttcatt acacacagct gaagtgcagg gctgtgtggt cggaattctt 3240 acacaagagc cgggaccgcg ccctggagcc tttctgtcca aacaacttga ccttactctt 3300 ttagcctagc ccttacgtct gcgtgtggtg gctgccgctg ctttaatact tttagaggcc 3360 ctcaaaatca caagctatgc tccacttact ctctacagtt cccataactt tcaaaatcta 3420 ttttcctcct cacacttgac gcatatactt tctgcccccc agctctttca gctatactca 3480 ctctttgttg agtctcccac agttactatt gttcctggcc cagacttcaa tccggcctcc 3540 cacattattc cggataccac acctgatccc catgactgta tctctctgat ccacctgaca 3600 ttcactccat ttccccatat ttccttcttt cctgttcctc accctgataa cacttggttt 3660 attgatggca gttccaccag gcctaatcgc cactcaccag caaagggagg ctatgctata 3720 gtatctttca catctatcat tgaggctacc actctgaccc cctccactac ctctcagcaa 3780 gctaaactca ttgccttaac ttgggccctc attcttgcaa aaggactacg agtcaatatt 3840 tatactgact ctaaatatgc cttccatatc ctgcaccacc atgctgttat atgggcagaa 3900 agaggtttcc tcactactca agggtcctcc atcattaatg cctctttaat aaatactctt 3960 ctcaaggctg ttttacttcc aaaggaagct ggagtcattc actgcaaggg ccatcaaaag 4020 gcatcagatc ccactgctca gggcaacgct tatgctgata aggtagttaa agaagcagct 4080 agctttccaa cttctgtccc tcacggccag gactggacag tactttgccc ttctcagaat 4140 tagagcctgt cctcgagatg ctacagggta ctgtccattt gaacttttat atggacgcac 4200 tttcttgctc agccctgacc tcgtcccaga caccagccct ctaggcaact atcttccagt 4260 cctccagcag gctagacagg aaattcgcta ggctgctcat cttctcttgc ctactccaga 4320 ttcccagcca tatgaagaca ccctagctgg atgatcagtt cttgttaaga atctgacccc 4380 tcaaactcta caacctccat ggactggacc ccacttagtc atctatagta ccccaatggc 4440 tgttcgtctg caggatgccc caccattagg ttcatcattc cagaataaag ctgtgcccgt 4500 caaacagcca gcctgatctc tcctcttcct cctggaagtc acaagtgttc acccctactt 4560 tccttaaact tatttgcatt tctgaagagc agtaataacc cttatgagcc taatacaacc 4620 cttcattcta ttaggtctat tcatccttac cctacttttt gcaatagggc tttacgcagt 4680 cacccccact acttgttctg tgccccaaaa acttgtcatc cctatcttct gtctagtcat 4740 actcctattc accattctca actacttgta aatgccctgc ccttgtttac actgctggtt 4800 tacgcttttc ctccaaacca ttgtagcgga tatctcctgg tactatcccc aatccgccac 4860 tcttgactcc ctcttagagt ggatagatga actttgctga cagggcaccc tccgatactt 4920 ttaccctgat gaagtcctat tctttacttt tatactcact cttattctca ttcccattct 4980 tatgccatcc tctacctctc cccagctatc tccaccacac tatcaatctc actcactctc 5040 tcctagctgt ttctaaacct tctttaacaa acaattgctg gctttgcatt tctctttcct 5100 ctaaaatcac agaggcctcg acttactcac tgctaaaaaa aaaaaaaaag ggggactctg 5160 ggccaggcgc agtggctcat gcctgcaatc ccagcacttt ggaacactga ggtgggcaga 5220 tcacgaggtc aggagatcga gaccatcctg gctaacacag tgaaattctg tctctactaa 5280 gaatacaaaa acttagctgg gcgtggtggc gggtgcctgt agtcccagct tcttgggagg 5340 ctgaggcagg agaatggtgt gaacccggaa ggcggagctt gcagtgagcc gagatcacgc 5400 cactgcactc cagcctgggc aacaaagcaa gagtctgtct caaaaaacaa aaacaaaaac 5460 aacaaaaaac attttttaaa tgaagagtgt tgtttttacc taaatcaatc tggcctggta 5520 tatgacaaca taaaaaaact caaggataga gccccaaaac tcgccaacca atcaaataat 5580 tacgctgaac ccccttggac actctctaat tggatatcct gggtcctccc aattcttagt 5640 cctttaatac ctgtttttct ccttctctta ttaggacctt gtgtcttccg tttagtttcc 5700 caattcttac aaaaccgcat ccaggccatc accaatcatt ctatatgaca aatgctcctt 5760 ctaacaaccc cacaatatca ccccctaccc caaaatcttt cttcagttta atctctccca 5820 ctgtaggttc ccatgccacc cctaatcctg ctcgaagcag cccagagaaa cattgctcat 5880 tatctctcca catcgcccct aaaaaatttt cgccacccca acacttcacc accattttgt 5940 tttgtttttc ttattaatat aagaagacag gaatgtcagg tctctaagcc caagctaaat 6000 catcatatcc tgtgacctgc atgtatacat ccagatggcc tgaagcaact gaagatccac 6060 aaaagaactg aaaatagcct taactgatga cattctacca t 6101 <210> 180 <211> 451 <212> DNA <213> Homo sapiens <400> 180 gtcaggcctc tgagcccaag ctaagccacc gtaacccctg tgacctgcac gtatacatcc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa atgtaaatgg cctgttcctg 120 ccttaactga tgacattcca ccacaaaaga agtgaaaatg gccggtccct gccttaactg 180 ataaccttgt gaaattcctt ctcctggctc atcctggctc aaaagctccc ccactgagca 240 ccttgtgacc ccaccccgcc cgccagagaa caacccccct ttgactgtaa ctttccttta 300 cctacccaaa tcttataaaa acggccccac ccctatctcc ctttgctgac tctcttttcg 360 gacttagccc gcctgcaccc aggtgaaata aacagccttg ttgctcacac aaagcctgtt 420 tgatggtctc ttcacatgga cgcaagtgaa a 451 <210> 181 <211> 5720 <212> DNA <213> Homo sapiens <400> 181 gtcaggcctc tgagcccaag ccaagccatc gcatctcctg tgacttgcac atatatgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aaggccctgc cctgccttaa 120 ctgatgacat accaccattg tgatttgttc ctgccccacc ttaactgagt gattaaccct 180 gtgaatttcc ttctcctggt acagaagctc ccccactgag caccttgtga ccccgcccct 240 gcccaccaga gaacaacccc ctttgactgt aattttccat taccttccca aattctataa 300 aatggcccac ccctatctcc cttcgctgac tctcttttcg gactcagctc tcctgcaacc 360 aggtgaaata aacagccatg ttgctcacac aaaccctgtt tggtggtctc ttcacacaga 420 cgcgcatgaa atttggtgcc gtgactcgga tggggggacc tcccttggga gatcaatccc 480 cccgtcctcc tgctctctgc tccgtgagaa agatccacct atgacctcag gtcctcagac 540 cgaccagccc aagaaacatc tcaccaattt caaatccggt aagtggcctc tttttactct 600 cttctccaac ttccctcact atccctcaac ctctttctcc tttcaatctt ggcgccacac 660 ttcaatctct cccttctctt aatttcaatt cctttcattt tctggtagaa acaaaggaga 720 cacattttat ccgtggaccc aaaactccgg cgccggtcac ggactgggaa ggcagccttc 780 ccttggtgtt taatcattgc agggacgcct ctgattattc acccacgttt caaaggtgtc 840 agaccatgca gggacgcctg ccttggtcct tcacccttag cggcaagtcc cgcttttcta 900 ggggaggggc aagtacccca accccttctc tccgtgtctc taccccttct ctgattttct 960 ggggcaaggg caagaacccc tcaacccctt ctccttcccc tcagtggcaa gtcccgcttt 1020 tctaggggag gtgcaagtac cccaacccct tctctccgtg tctctacccc ttctctgctt 1080 ttctggaggg gggggcacgt accccaacct tgtatctctg caccctgatc ccttatttcc 1140 atgccccaac ctcatatctc tgcaccccga ccccttctct gcttttctgg agggcaagaa 1200 acccccaccc cttctccatg tctctactct tttctctggg cttgcctact tcactatggg 1260 caagcttcca ccttccattc ctccttctcc cttagcttgt gttcttaaga acttaaaacc 1320 tcttcagctc tcacctgacc taaaatctaa gtatcttatt ttcttctgca atgccacttg 1380 accccaatac aaactcgaca gtagttccaa atagccagaa aaacggcact ttcaattttt 1440 gcatcctaca agatctaaat aattcttgcc gtaaaatggg caaatggtct gaggtgcctg 1500 acgtccaggc attcttttac acatcggtcc cttcctagtc tctgtgccca gtgcaactca 1560 tcccaaatct tccttctttc ccctcccgcc tgtcccctca gtcccaaccc caagcatcac 1620 tgagtctttc taatcttcct tttctacaga cccatctgac ctctcccttc ctcaccaggc 1680 caagctaggt cccgattctt cctcgcctcc gcccctccac cctataatct ttttatcgcc 1740 tcccctcctc acacctggtc tggcttacag tttcgttccg tgactagccc tccaccacct 1800 gcccagcaat ttactcttaa aaaggttgct ggagccaaag gcatagtcaa ggttaatgct 1860 cctttttctt tatcccaaat cagaagtgtt taggctcctt ttcatcaaat ataaaaaccc 1920 agcccagttt atggctcgtt ccacagcaac cctgagacgc tttacagccc tagaccctaa 1980 aaggtcaaaa ggccatcata ttctcaatat acattttatt acctaatctg ctcccgacat 2040 taaataaaac tccaaaaact ggaatctggc cctcaaaccc cacaacagga cttcattaat 2100 ctcaccttca aggcgtacaa taataaaaaa aaagttgcaa ttccttgcct ccactgtgag 2160 acaaacccca gccacatctc cagcacacaa gaacttccaa acgcctgaac cacagcagcc 2220 aggagttcct ccagaacctc ctcccacagg agcttgctac aagtgccaga aatctgacca 2280 ccaggccaag gaatgcctgc agcccaggat tcctcctaag ccgtgtccat ctgtgcggga 2340 ccccactgga aatcggactg ttcaactcac ctggcaggca ctcccagagc ccctggaatt 2400 ctggcccaag gctctctgac tccttctcgg cttagcagct gaagactgac gctgcccgat 2460 cacctcgaaa gccccataga tcatcacaga cgctgagctt cgagtaactc tcacagtgga 2520 aggtaagtcc gtccccttaa tcaatatgga gcctacccac tccacattac cttcttttca 2580 agggcctgtt tcccttgcct ccgtaactgt tgtaggtatt gacggccagg cttctaaacc 2640 tcttaaaact ccccaactct ggtgccaact gagacaatac tcttctaagc actcttttag 2700 ttatccccac ctgctcagtt cccttattag gccgagacac tttaactaaa ttatctgctt 2760 ccctgactag tcctggatta cagctacatc tcattgctgc ccttcttccc aatccaaagc 2820 ctcctttgcg tcctcctctt gtattccccc accttaaccc acaggaataa gatacctcta 2880 ctccctcctt ggtaactgat catgcacccc ttactatctc attaaaacct aatcaccctt 2940 accccgctca atgccaatat ctcatcccac accatgcttt gaaaggatta aagcctgtta 3000 tcacttgcgt gctacagcat ggccttttaa agcctataaa ctctccttac aattccccca 3060 ttatacctgt cctaaaacca gacaagcctt ccaagttagt tcgggatcta tgccttatca 3120 accaaattgt tttgcctatc caccctatgg tgccaaaccc atatactctc ctatcctcaa 3180 tacctccctc cacaatccat tattctgttc tggatctcaa acatgttttc tttactattc 3240 ctttgcaccc atcatcccag cctctcttcg ctttcagctg gactgaccct aacacccatt 3300 aggctcagca aattacctgg gctgtactgc cgcaaggctt cacagacagc ccccattact 3360 tcagtcaagc ccaaatttca ccctcatctg ttacctatct cagcataatt ctcataaaaa 3420 cacaggtgct ctccctgctg atcgtgtcca attaatctcc ccaacctcaa tcccttacaa 3480 aacaacaact cctttccttc ctaggcatgg ttagtgtggt cagaattctt acacaagagc 3540 caggaccgca ccctgtagcc tttctgtcca aacaacttga ccttactgtt ttagcctagc 3600 cctcatgtct ccgtgcagcg gctgctgcca ccctaatact tttagaggcc ctaaaaatca 3660 taaactatgc tcaacttact ctctacattt ctcataactt ccaaaatcta ttttcttcct 3720 catacctgat gcatatactt tctgctcccc ggctccttca gctgtactca ctctttgtta 3780 agtcccacaa ttaccattgt tcctggccca gacttcaatc tggcctccca cattattcct 3840 gataccacac ctgaccccca tgactgtatg tctctgatcc acctgacatt caccacattt 3900 ccccatattt ccttctttcc tgttcctcac cctgatcacg cttgatttat tgatggcagt 3960 tccaccaggc ctaatcgcca cacaccagca aaggcaggct atgctatagt acaagccact 4020 agcccgcctc ttagaacctc tcatttcctt tccattgtag aaatctatcc tcaaggaaat 4080 aatttctcag tgttccatct gctattctat ctgctattct actactcctc aaggattatt 4140 caggacccct cccttcccta cacatcaaac ttgaggattt gccccctgcc cccgcccccg 4200 gaactggcaa attagcttta ctcaacatgc cctgagtcac aaaaactaaa atacctctta 4260 gtctaagtag acactttcac tagataggta gaggcctttc ctacagggtc tgagaaggcc 4320 actgcagtca tttcttccct tctgtcagac ataatccctc agtttagcct tcccacctct 4380 atacagtctg ataacagacc aacctttatt agtcaaatca gccaagcagt ttttcaggct 4440 cttagtattc agtgaaacct ttatatccct tatagtcgtc tgtcttcaag aaaagtagaa 4500 cggactaaag gtctttcaaa aacacacctc accaagctca gccaccaact taaaaagaac 4560 tggacaatac ttttaccact ttcccttctc agaagtcaga cccgtcctca gaatgctaca 4620 aggtacagcc catttgggct cctgtataga tgctcctttt tattaggccc cagtctcatt 4680 ccaaacaccg gaccaactta gagtgtgccc caaaaaaaac ttgtcatccc tactatcttc 4740 tgtctagtca tactcctatt ctccgttctc aactactcat acatgccctg ctcttgttta 4800 cactgccggt ttacactgtt tctccaagcc atcacagctg atatctcctc gtgctatccc 4860 caaaccgcca ctcttaactc ttgaagtaaa taaataatct tggctggcag gactatgctg 4920 aatctcctta ggcactctct aatcagatgt cctaggtcct cccaattctt agacctttta 4980 tacctgtttt tctccttctc ttattccatt tagtttttca attcatacaa aaccgtatcc 5040 aggccatcac caatcattct aaatgacaaa tgtttcttct aacaacccca caatatcacc 5100 ccttaccaca aaatcttcct tcagcttaat ctctcccact ctaggttccc acgccgcccc 5160 taatcccgct tgaagcagcc ctgagaaaca tcgtccattc tctctccata tcaccccccc 5220 aaaattttca ccaccccaag acttcaacac tgttttattt ttcttattaa tataagaagg 5280 caggattgtc aggcctctga gcccaagcca agccatcgca tctcctgtga cttgcacata 5340 tatgcccaga tggcctgaag taactgaaga atcacaaaag aagtgaaaag gccctgcccc 5400 gccttaactg atgacattcc accattgtga tttgttcctg ccccacctta actgagtgat 5460 taaccctgtg aatttccttc tcctggctca gaagctcccc cactgagcac cttgtgaccc 5520 ccaaccctgc ccaccagaga acaaccccct ttgactgtaa ttttccatta ccttcccaaa 5580 tcctaaaaaa cggccccacc cctatctccc ttcgctgact ctcttttcag actcagcccg 5640 cctgcaccca ggtgaaataa acagccatgt tgctcacaca aaccctgttt ggtggtctct 5700 tcacacaaac gcgcatgaaa 5720 <210> 182 <211> 7257 <212> DNA <213> Homo sapiens <400> 182 gtcaggtctc tgagcccaag ctaagccatc ataacccctg tgacctgcac gtatacatcc 60 agagggcctg gagcaactga agaaccacaa aagatgacat tccaccattg tgatttgttc 120 ctgccccacc ccaactaatc aatcgatctt gtgacattcc tcccctggaa aatgagtctc 180 atgatctccc catcctgcac cttatgactc ctgtggctgc ctgcaagaga taaccacctt 240 caactgtaat tttccactat ctacccaaat cctataaaaa gtgccccacc ccatctccct 300 ttgctgactc cttttttgta ctcagcccac ctgcacctag gtgattaaaa agctttatta 360 cttgcacaaa gcctgtctgg tggtctcttc acacggactc atgtgacatt tggtgctgga 420 gacccaggac agggagactc cttcaggaga ctggtcccct gtcctcgcct ctctttgtga 480 ggagatccac ctacaatgtc aggtcctcag actagcctaa ggaacatctc tccaatttta 540 aattgggtaa gcagcctttt ttattctctt ctccaacctt tctcactatc cttccaccct 600 tcaatctctc ccttccttaa ttttggttcc tttccctttc tggtagagac agaggagacg 660 cgttttatct gtgaactcaa aactccggtg ctggtcatgg actcgggaag ccagtcttcc 720 cttggtgtct aatcactgca gggatgcctg cctgattatt cacccacatt ccaggtgtgt 780 ctgatcaccg cagggacccc tgccttgatc cttcaccttt gtggcaagta ctacctcccc 840 tgggtggcaa gtaccacctc cccttggtgg caagtaccac ctcctgtggg tggcaagtac 900 cacctccctc cctccgtgtc tctaccctat cttttctcta aacttacctt tttactatgg 960 gcaaccttcc gccctccatt cctccatctt ctcccttagc ctgtgttcca aaaaacttaa 1020 aacctcttca actctcacct gacctaaaac ctaagcctct tattatcttc tgcaatacca 1080 cttggcccca atacaaactc ggcagtggct ctaaatggcc agaaaatgac actttcaatt 1140 cctccatcct acaagatcta gataattttt gtcgtaaaat gggcaaatgg cctgaggtgc 1200 ctgatgtcca ggcattcttt tacacattgg tccctcccta gtatctgctc ccaatgtgac 1260 tcatcccaaa tctttcttca ttctcctttc tctcctgtct gtcccttcag tctccacccc 1320 aagctctgag tcctttgaat cctccttttc tacagaccta tctgacctct cccctcctcc 1380 tcaggctgct cctcgccagg ccgagccaag tcccaattct tcctcagcct ccactccccc 1440 accctataat ccttctatca cctcccatcc tcacacccag tccagcttac agttttgctc 1500 cgcgactagc cctcccaaca atctcctctt ggagaggtgg ctggagctga aggcatagtc 1560 aaggttaagg ctccttttct ttatccaccc tgtcccagat cagttagtgt ttgggctagt 1620 tttcatcaaa tataaaaacc cagcccagtt catggcccat ttggcaacaa cccttagacg 1680 ctttactgcc ctagccccag aggggccaga aggctgtctt attctcaata tgcattttat 1740 taccaatctg ctcctgacat tagaaaaagc tccaaaaatt agattccagc cctcaaaccc 1800 cacaacagga tttaattaac ctcgccttca aggtgtacaa taatagagaa gaggcagtca 1860 agcaacaacg tatttctgag ttgcaattac ttgcctccgc tgtgagagaa accccagcca 1920 catctccagc acacaagaac ttcaaaatgc ctaaactgca gcagccaggc attcctccag 1980 gacctcctcc ctcaggatct tgcttcaagt gctggaaatc tggccactgg gccaagaaat 2040 gcccgcagcc caggattcct cctaagccat gtcccatctt tgtgggaccc cactggaaat 2100 cggactattc aacttgccca gcagccactc ccagagcccc tggaactctg gcccaaggct 2160 cttggactga ctcctttcca gatcttctca ccttagcggg tgaagactga cactgcccaa 2220 ttgcattgga aacctcctgg accatcacag atgctttggg taacttttac agtggagggt 2280 aagtctctcc ccttcttaat caatatggag gctacccact ccacattacc ttcttttcaa 2340 gggcctgttt cccttgcctc cataactgtt gcaggtattg acggccaggc tgctagaccc 2400 cttaaaactc cctcactctg gtgccaactt ggacaacatt cttttatgca ctttttcagt 2460 tttccccacc tgcccagttc ccttattagg ttgagacatt ttaactaaat tatctgcttc 2520 catgactatt cctggactac agccacatct catcgctgcc cttctcccca acccaaagcc 2580 tcctttgtgt cttcctctca tatcccccaa ccttaatcca caagtctggg acacctctac 2640 tccctccctg gcaaccgatc acatgcctat tactatccca ttaaaaccta atcaccctta 2700 cccgctcaac accagtatcc catcccacat aggctttaag gggactaaag cctgttatca 2760 tctgcatgtt acaacatggc ctcttaaagc ctacaaattc tctttataac tcccctatcc 2820 tacccatcca gaaaccagac aagtcttaca ggttggttca ggatctttgc cttattaatc 2880 aaatcgtcct tcccatccat cctatagtgc caaacctgta caccctccta tcttcaatac 2940 ctccttccgc aattcactat tccattcttg atcttaaaga tgcttttttc actattcccc 3000 tgcacccctc gtcccatcct ctctttgctt ttacctggac tgaccctgat atccatcagt 3060 cccagtagct tacctgggct atactgccac aaggcttcag ggaccgtcct cattagttca 3120 gccaagctct ttctcatgat ttactttctt tccacccctc tgcttctcac cttattcaat 3180 atattgatga ccttctactt tgtagcccct cctttgaatc ttctcaacaa gacaccctcc 3240 tgttccttca acatttattc tccaagggat atcgtgtatc cccctccaaa gctcaaattt 3300 cttcctcatc tgttacctac cttggcataa ttcttcatga aaacacaagt gcacttcctg 3360 ccaattgtgt ccagctgatc tctaaacccc aaccccttct acaaaacaac aactcctttc 3420 cttcctgggc atggttggat actttcacat ttggatacct ggttttgcca tcctaacaaa 3480 accattatat aaactcacaa tgggaaacct agctgacacc atagatccta aatcctttcc 3540 ccactcctct ttctgttcct taaaaacagc tctggagact cctcccacac tagctctccc 3600 tgactcatcc caaccttttt cattacacac aaccaaagtg cagggctgtg cagtcggaat 3660 tcttacacaa ggatcgggac cacgccctgt agcctttttg tccaaacaac ttgaccttac 3720 tgttttaggc tggctctcat gtctgcatgc agcagctgct gctgctctaa tacttttaga 3780 ggccctcaaa atcacaaact atgctcaact cactctctac agttctcata actttcaaaa 3840 actattttct tcctcacatg tgacgcatat actttctgcc ccccagctcc ttcagctata 3900 ctcactcttt gttgagtctc ctacaattac cattgttcct ggcccggact tcaatccagc 3960 ctcccacatt attcctgata ccacacctga tccctatgac tgtatctctc tgatccacct 4020 gacattcact ccattaccca tatttccttc tttcctgttc ctcaccctga tcacacttgg 4080 tttattgatg gcagtaccac caggcctaat cacaattcac cagcaaaggc aggctatgct 4140 atagtatctt ccacatctat cattgaggct accactctgc cccactccac tacctctcag 4200 caaaccaaac tcctagactt aactgaagcc ctcactcttg caaaatgact gcatgtcaat 4260 atttatactg actttatata tgccttccat atcctgcacc accatgctgt tatatgggct 4320 gaaagaggtt ttctcactac gcaagggtcc tccatcatta atgcctcttt aacgaaaact 4380 cttcacaagc ctgctttact tccaaaggaa gctggagtcc ttcactgcaa aggccatcaa 4440 atggcctcag accccattgc tcaaggcaac aattatgctg ataagacagc aaaagaagca 4500 gccagtattc ctacttcttt cactcacggc cggtttttct ctttctcatc agtcattcct 4560 acttactctc ccactgaagt ttccacctat caatccctcc ccactcaagg caaatggttc 4620 ttggaccaag gaaaatatct ccgtccagcc tcagaggccc attctattct gtcatccttt 4680 cataacctct tccatgtagg ttacaagcca ctagcccatc tctcagaacc tctcatttcc 4740 tttccatcat ggaaatctat cctcgaggaa atcacttctc agtgttccat ctgctattct 4800 actactcctc agggattgtt caggccccct cctttcccta cacatcaagc tcaggggttt 4860 gcccctgccc aggactggga aattgacttt actcctggga aactccagga aacttggagt 4920 ttcctgctcc aagtcaggaa actaaaatac ctcttggtct gggtagatac tttcactgga 4980 taggtagagg tctttcctac agcatctgag aagaccacca ttgtcatttt ttcccttcta 5040 tcagacataa ttcctcagtt tggccttccc acctctatac agttcaataa tggactggcc 5100 tttattagtc aaatcaccca agcaatttct caggctcttg gtattcagtg gaaccttcat 5160 accccttagc atcctcaatc ttcaggaaag gtagaacaga ctaatggtct tttaaagaca 5220 cacctcacca agctcagtga ccaacttaaa aaggactgga cagtactttt acctcttgcc 5280 cttctcagaa ttagtctgtc ctcgagatgc tacagggtac agtccacttg aacttttata 5340 tggacgcact ttcttgctca gccccaacct cgtcccagac accagctctc tagatgacta 5400 tcttccagtc ctccagcaga tgagacagga aattcaccag gctgctagtc ttctcttgcc 5460 tactccagat tctcagccat atgaagacac cctagctgaa cgatcagttc ttgttaagaa 5520 tctgacccct caaactctac aacctcaatg gaccggaccc tgcttagtca tctatatacc 5580 ccaactgcag gcctgcagga ccctctccat tcctgttcta gtgattgccc ccctccatat 5640 cactgttcca gaataaagct gtatctgtca gccagccagc ctgatctctc ctcttcctcc 5700 tggaagtcgc aagtactcac ccctacttcc cttgaactca gtttcatttc tgaagaacag 5760 taataacact tatgagccta atacatctct tcattctatt acgtctattc atccttaccc 5820 tactttttgc aacagggctt tacatagtca cccccactac ttggaccgca ccctaaaaac 5880 ttgtcatccc tactatcttc tgtctagtca tactcctatt caccattccc aactactcat 5940 aaatgccctg cccttgttta cactgccagt ttacactttt tctctaaacc atcataactg 6000 atatctccta gttttacctc aaactgccat tcttgactcc ctcttggagt gggtaggtga 6060 tctttgctga cagggcaccc tccaatactt tcaccctgat gaagtcctat tctttacttg 6120 tatactcact cttattctcg ttcccgttct tatgccaccc tctacctctc cccagctatc 6180 tccaccacac tatcaatctc actcactctc tcctagctgt ttctaatcct tctttaacaa 6240 acaattgctg gctttgcatt tctctttcct ccaaaaccac tgaggcctca acttactcac 6300 tgctaaaaaa aaaaaaaaga ggactctgta tatttttaaa tgaagaatgt tgtttttacc 6360 taaatcaatc tggcctggta tagaaaaaca taaaaaaaaa aaaaaacaaa ctcaaggata 6420 gagccccaaa actcgccaac caagcaaata attatgctga acacccttgg atactctcta 6480 attggttgtt ctgggtcctc ccaattctta gtcctataat acctgttttt ctccttcttt 6540 tattcagacc ttgtatcttc catttagttt ctcaattcat acaaaactgc atccaggcca 6600 tcaccaatca ttctatatga caaatgctcc ttctaacaac cccacaatat caccccttac 6660 cgcaaagtct ttcttcagtt taatctctcc cactcaagtt cccacattgc ccctaatcct 6720 acttgaagca gccctgagaa acatcaccca ttatctctcc ataccacccc caaaattttt 6780 tgctgcccca gcacttcacc actattttgt tttgtttttc ttactaatat aagaagacag 6840 gaatgtcagg cctctcagcc caagctaagc catcataacc cctctgacct gcatgtatac 6900 atccagaggg cctggagcaa ctgaagaacc acaaaagatg atattccacc attgtgattt 6960 gttcctgccc cactccaact aatcaatcga ccttgtaaca ttcctcccct ggacaatgag 7020 tctcatgatc cccccatcct gcaccttgtg accaccgccc ctgcctgccc tgcaagagat 7080 aaccacgttt aactgtaatt ttccactacc tacccaaatc ctataaaact gcctcacctc 7140 tatctccctt tgctgactct ctttatggac tcagcccact tgcacccaag tgaaataaac 7200 agccttgctg ctcacacaaa gcctgttggt ggactctctt cacatgtact tgcgtga 7257 <210> 183 <211> 713 <212> DNA <213> Homo sapiens <400> 183 tcaatccatc aagacccttt cacgtggaac cccttaaagc tgtaagccct taaacgggcc 60 aggaactctg tcttccttcc gggagctcgg ctcttaagac gcgagtctgc cgaagctccc 120 agcggaataa aaaaaactct tccttcttta atccgctgtc tgaggggttt tgtccgctgc 180 tcatccatgc tccatttctt tgttccctga ccgggaatcg aacgcaggca gcagcggtga 240 gagcaccgaa tcctaagcac tagaccacca ggggaactta gaaccttgtg ggaaatagat 300 tgcgcaccat tagaagtggg ttggccatca gaaggaagcc tggacaggtc ccttgtttct 360 aaggcgtggc acaaggtaac tggtaaagat acctagacca gttcccatac atagacactt 420 ggtgacagct ggtgctagaa cccccacagt ggctgagggc atgcagcagc aatactagta 480 gcaaagggac agatagctaa ggaaggatcc cgctccactc acccagggaa atcaactcct 540 gaagttctgt tcgaccccac atcagaggat ccattgcagg agatggcacc agagatccca 600 gtggtgtcct ccccttaaca gggaaagagg ctccccactc ttgagcccac agtgcttgtg 660 cctccacaag acaagcatat ccctaggcca cccagagtag acaagagagg agg 713 <210> 184 <211> 5792 <212> DNA <213> Homo sapiens <400> 184 agccatcata tcccctgtga cctgcaggta cacatccaga tggctggttc ctgccttaaa 60 tgatgacatt ccaccacaaa agaagtgaaa atggtcagtt cctgccttaa ctgatgacat 120 tatcttgtga aattccttcc cctggctcat cctggctcaa aagctcccct actgagcaac 180 ttgtgacccc cccactcctg cccgccagag aacaacaccc ctttttcctt taccgaccca 240 aatcctataa aacggcccca ccccatctcc cttcgctgac tctcttttca gactcagcct 300 gcctgcaccc tggtgattaa aaaactttat tgttcacaca aagcctgttt ggcaatctct 360 tcatacagat acgagtgaaa tttggtgctg tgactcggat tgggggacct cccttgggag 420 atcaatccct gtcctcctgc tctttgctcc ttgagaaaga tccacctaca acctcaggtc 480 ctcagactga ccagcccaag aaacacctca ccaatttcaa atctggtaat cggcctcttt 540 ttactctctt ctccaacctc cctcactatc cctcaaactc tttcaccttt caatcttggt 600 gtcacacttc aatctctccc ttctcttcat ttcaattcct ttcattttct ggtagagaca 660 aaggagacgc gttttatcca tggacccaaa actctggcgc cggtcacgga ctgagaaggc 720 agccttccct tggtgtttaa tcactgcagg gacgcctctc tatacaccca cgtttcagag 780 gtgtcagacc atgcagggat gcctggcttg gtccttcacc cttagtggca agtcccactt 840 ttctgggaga ggggcaagaa cccctcaacc ccttctcctt cacccttagc agcaagtcct 900 gcttttctag ggggcaataa cccccaatcc cttatttccg cgccctgacc tcttatctct 960 gtgcctcgat cccttatttc tgcaccccaa cctcctatct ctgcacccca aacccttatt 1020 tctgtgctcc gaccccttct ctgcttttct ggagggcaag aacgccacac cccttctctg 1080 tgtctctact ctcttttctc tgggcttgcc tccttcacta tgggcaagct tccaccttcc 1140 attcctcttt cttctccctt agcctgtgct ttcaagaact taaaacctct tcaactctca 1200 cctgacctaa aatctaagca tcttattttc ttctgcaatg ccacttcacc ccaatacaaa 1260 ctcgacagta gttccaaata gccagaaaac agcactttca atttttccat cctacgagat 1320 ctaaataatt cttgtcgtaa aataggcaaa cactctgaga tgcctgacgt ccaggtattc 1380 ttttacacat tggtccctcc ctagtctctg ttcccaatgc aactcatccc aaatcttcct 1440 tctttccctc ccatctgtcc cctcagtccc gaccccaagt gttgctgact ctttctaatc 1500 ttccttttct acaaacccat ctgacctctc ctctgctcgc caggctgtgc taggtcccaa 1560 ttcttcctca gcctctgctc ctccacccta taatcctttt atcacctccc ctcctcacac 1620 ccagtccggc ttacagtttg gttccatgac tagccctgcc ccatctgccc agcaatttac 1680 tcttaaaaag gtggctggag ctaaaggcat agtcaaggtt aatgctcctt tttctttatc 1740 ccaaatcaga tagcgttcag cctctttttc atcaaatata aaaattcagc ccagttcatg 1800 gctcatttgg cagcaaccct gagatgcttt acaaccctag accctaaaag gtcaaaaggc 1860 cgtctattct caatatacat tttattaccc tatctgctcc caaaattaaa taaaactcca 1920 aaaattaaat tccggccctc aaaccccaca acaggactta acctcacctt caaggtgtgt 1980 aataatagag tagaggcagc caagtagcaa catatttctg agttgcaatt ccttgcctcc 2040 actgtgagac aaaccccagc cacatctcca gcacacgaga acttccaaat gcctaaaccg 2100 cagtggccag gcattcctcc agaaccatct cccccaggag cttgctacaa gtgccagaaa 2160 tctggccagc aggccaagga atgcctgcag cccaggattc ctcctaagtc gtgttccatc 2220 tgtgcaggac cccactggaa atcagactgt tcaactcagc tggcagccac tcccagagcc 2280 cctggaactc tggcccgagg ctctctgact gactccttcc cagatcttct tggcttagtg 2340 gctgaagact gacgctgacc aattgcctcg gaagccccgt agaccatcac ggacgccaac 2400 ctttaggtaa ctctcacagt ggacggtgag tctgtcccct tcttaatcaa tacagaggct 2460 acccactcca cattaccttc ttttccagag cctgtttccc ttgcctccat aactgttgtg 2520 ggtattgaca gccagccttc taaacctctt aaaagtcccc aactctggtg ccaacttaga 2580 caatactctt ttaagcactc ctttttagtt atccccacct gcccagttcc cttattaggc 2640 cgagacactt taactaaatt atctgcttcc ctgactattc ctggactaca gctgtatctc 2700 actgccaccc ttcttcccaa tccaaagcct cctttgtgtc ctcctcttgt atcccctgac 2760 cttaacccac aagtataaga tacctctact ccctccttgg tgacctatca tgcacccctt 2820 accatctcat taaaacctaa tcacccttac cccactcaat gccaatatcc catcccacag 2880 catgcttcga aaggattaaa gcctgttatc actggcctgc tacagcatgg ccttttaaag 2940 cctataaact ctccttacaa ttcccccatt atacctgtcc taaaaccaga caagccttac 3000 aagttagttc aggatctgcg cattatcaac caaattgttt tgcctatcca ccccatggtg 3060 ccaaacccat atactctcct atcctcaata cctccctcca caatccatta ttctgttctg 3120 gatctcaaac attctttctt tactattcct ttgcaccctt catcccagcc tctctttgct 3180 ttcacttgga ctgaccctga cacccatcag gctcagcaaa ttacctaggc tgtactgccg 3240 caaagcttca cagacagccc ccattacttc agtcaagccc aaatttcatc ttcctctgtt 3300 acctatctca gcataattct cataaaaaca cacgtgctct ccctgctgat cgtgtccaac 3360 taatctctca aaccccaacc ccttctacaa aacaacaact cctttccttc ctgggcatgg 3420 ttggatactt tcacctttgg atacctggtt ttgccatcct aacaaaacca ttatataaac 3480 tcacaaaagg aaacccagct gaacccatag atcctaaatc atttccccat cctctttcca 3540 ttccttgaag acagctttag agactgcccc caccctagct ctccctgact catcccaacc 3600 cttttcatta cacacagctg aagtgcaggg ctgtgcagtt ggaattctta cacaagaacc 3660 gggatcacgt cctgtagcct ttttgtctaa acaacttgac cttactgttt taggctggcc 3720 atcatgtctc cgtgcagtgg ctgctgccac tctaatactt ttagaggccc ttataatcac 3780 aaactatgct caactcactc tctagagctc tcataatttc caaagtctgt tttcttcctc 3840 acacctgaca catatacttt ctgctccctg gctccttcag ctatactcac tatttgttga 3900 gtctcccaca attaccattg ttcctggcct ggacttcaat ccggcctccc acattattcc 3960 tgataccaca cctgaccctc atgactgcat ctctctgatc cacctgacgt tcaccccatt 4020 tccccacatt ctcttcttcc ctgtttctca ccctgatcac acttgattta ttgatggcag 4080 ttctacaaga cctaatcacc acacagcagc aaaggcaggc tatgctatag tacaagccac 4140 tagccggcct cttagaacct ctcatttcct ttccattgta gaaatctatc ctcaaggaaa 4200 taacttctca gtgttccatc tgctattcta ctactcctca gggattattc aggccccctc 4260 ccttccctac acatcaagct cagggatttg ccccctccca ggactggcaa attagcttta 4320 ctcaacatgc cctgagtcag gaaactaaaa tacctcttgg tctcagtaga cgctttcact 4380 ggacaggtag aggcctttcc cacagggtct aagaagacca ccatggtcat ttcttccctt 4440 ctgtcagaca taattcctcg gtttggcctt cccacctcta tgaagtctga cagcagaccg 4500 gcctttatta gtcaaatcag ccaagcattt tttcaggctc ttagtgttca gtgaaacctt 4560 tatatccctt acagttctca gtcttcagga aaggtagaaa agactaatgg tcttttaaaa 4620 acacacctca ccaagctcag ccatcaactt aaaaaggacc ggacaatact tttaccactt 4680 tcccttctca gaattcaggc ctgtcctcag aatgctataa ggtacagccc atttgagctc 4740 ctatatagac gctccttttt attaagcccc agtctcattc cagacaccag accaacttag 4800 actgtgtccc aaaaaacttg tcatccctac tatcttccat ctagtcatac acctattcac 4860 cattctcaac tattcataca tgccctgctc ttgtttacac tgcaggttta cactgtttct 4920 ccaagccatc atagctgata tctcctggtg ctatccccaa actgccactc ttaactctta 4980 aagtaaacaa ataatctttg ctggcaaggc tatgctgaac ctccttaggc actctctaat 5040 tagatgtcct aggtcctccc aattcttagt cctttaataa cctgtttttc tccttctctt 5100 attccgttta gtttttcaat tcatacaaaa ctgtatccag gccatcacca ataattctaa 5160 atgacaaatg tttcttctaa caaccccaca gtatcacccc ttaccacaaa atcttccttc 5220 agcttaatct ctcccactct aggttcccac gctgccccta atcctgcttg aagcagccct 5280 gagaaacatc gcccattatc tctccatacc accccccaaa aatgttcacc atcccaacac 5340 tttaccacta tttcatttta ttttacttat taatataaga agacaggaat gtcaggcttc 5400 tgagcccaag ctaagccatc atatcccctg tgacctgcac gtacacatcc agatggccag 5460 ttcctgcctt aactgatgac attccaccac aaaagaagtg aaaatggcct gttcctgcct 5520 taactgatga cattatcttg tgaaattcct tctcctggct catcctggct caaaagctcc 5580 cctactgagc accttgtgac ccccacttct gcccgccaga gaacacttct gccccctttt 5640 tcctttacct acccaaatcc tataaaacag ccccacccct gtctcccttc tcgctctttt 5700 cggactcagc ccgcctgcat ccagctaatt aaagagcttt attgctcaca caaagcctgt 5760 ttggtggtct cttcacacag acacgagtga aa 5792 <210> 185 <211> 5738 <212> DNA <213> Homo sapiens <400> 185 gaaaaattgc ctaataattt gtctgctcaa atgtgcgggc tgtttgcact cagccaagcc 60 ttaaagtact tacagaatca aaagactatc tcaatcctga ctcaaaaggt tacctacacc 120 ctctctgaaa caaatttgca taagaactgc ttttacggga acgcatcttg atggcgcagc 180 tgggttgtta ggaaatactc aggaacccag cccagctcta ggactcacct ctgagtgcaa 240 aggcaatgtt gggcatgctg gtaaaggacc actagaatcc agcagtgtgg actgctttct 300 ttgtggtcaa gaaaggtggg aaaacaggtg caggacttct acattggtca gcttaactaa 360 tccgataagc agaggtccat gggtggttac gcaccatgga aaggaactca cctctgagcg 420 caaaggcaat gctgggcatg ctggtaaagg accactagaa tccagcagcc caggcccctt 480 tctttatggt caagaaaggt gggaaaaggt gtgcaggact gctacatcgg tgagcataac 540 taatctaata agcagaggtc catgggtggt tatgaaccct ggaaaggaat aagcattagg 600 accatagagg atgctctatg actaatgctc atcagaaaat gactagggat gctggcatcc 660 ctgttatttt ttcagatggg aaatgttcct cccaaggcaa aaacacccct aagatgtatt 720 ctggagaact gggaccaatt tgaccctcag acactaagaa agaaacaact tatattcttc 780 tgcagtgccg cctggccatg ttatcctctt caagggggag aaatctggcc tcctgaggga 840 agtatacatt ataacaccat cttacagcta gacctctttt gtaggaaaaa aggcaaatgg 900 attgaagtgc catatgtaca aactttcttt tcattaagag acaactcaca attatgtaaa 960 aagtgtgatt tatgccctat aggaagccct cagagtctac ctccctaccc cagtgtcccc 1020 ccgactcctt ctccaactaa taagacctgt cttcaaccca aatggtccaa aaggagatag 1080 acaaaggggt aaacgatgaa ccaaagagtg ccaatattcc ccgattatgc cccctccaag 1140 cagtgggagg aggagaattc agcccagcca gagtgaatgt acctttttct ctctcagact 1200 taaagcaaat taaaatagac ctaggtaaat tctcagataa ccctgatggc tatattgatg 1260 ttttacaagg attagggcaa tcctttgatc tgatatggag agatataatg ctactgctag 1320 atcagacact aaccccaaat gagagaagtg ctgccataac tgcagcccaa gagtttggca 1380 gtctctggta tctcagtcag gtcaatgaca ggatgataac agaggaaaga gaatgattcc 1440 ccacaggcca gcaggcagtt cccagtgtag accctcactg ggacacagaa tcagaacatg 1500 gagattggtt ctgcagacat ttgctaactt gcatgctaca aggactaagg aaaactagga 1560 agaagcctat gaattattca atgatgtcca ctataacaca gggaagggaa gaaaatccta 1620 ctgcctttct ggagagacta agggaggcat tgagaaagca tacctccctg tcacctgact 1680 ctattgaagg ccaactaatc ttaaaggaaa agtttattac tcagtcagct gcagacatta 1740 ggaaaaaact tcaaaagtcc accttaggcc cggagcaaaa cttagaaacc ctattgaact 1800 tggcaacctc ggttttttat aatagcgatc aggaggaaca ggcagaatgg gacaaacagg 1860 ataaaaaaaa gaccaccgct ttagtcatgg ctctcaggca agtggacttt ggaggctctg 1920 gaaatgggaa aagctaggca aatggaatgc ctaatagggc ttgcttccag tgcagtctat 1980 ggggatactt taaaaaagat tgtccaagta ggaataagcc acgcccttgt ccacgctcct 2040 tatgtcaaag gaatcactgg aaggcccagt gccctagggg aggaaggtcc tctgagtcag 2100 aagccactaa ccagatgatc cagcagcagg attgagggtg cccagggcaa gcaccagccc 2160 atgccatcac cctcacaaag ccccgggtat gcttgaccat tgagggccag gaggctaact 2220 gtgtcctgga cattggcgtg gccttctcag tcttactctc ctgtcctgga caactatcct 2280 ccagatctgt cactatccga ggggtcctag gacagccagt cactagctac ttctcccagc 2340 cactaagttg tgactgggga actctactct tttcacatgc ttttctaatt atgcctgaaa 2400 gccccactcc cttgttaggg agagacattc tagcaaaagc aggggtcatt atacacccga 2460 acataggaga aggaacaccc atttgttgtc ccctgcttga ggaaggaatt aatcctgaag 2520 tctgggcaac agaaagaaaa taaggaagag caaagaatgc ctgtcctgtt caagttaaac 2580 taaaggattc cacctccttt ccctaccaaa ggcagtaccc ccttagacct gaggcccaac 2640 aaggactcca aaagattgtt aaggacctaa aagcccaagg cctagtaaaa ccatgcattc 2700 gcccctgcaa tactccaatt ttaggagtac agaaacccaa tggacagtag aggttagtgc 2760 aagatctcag gattatcagt gaagccattg tccctctata cccagctgta cctaaccctt 2820 acactctgct ttcccaaata ccagaggacg cagagtggtt tacagtcctg gaccctaagc 2880 atgccgtttt ctgcatccct gtacatcctg actctcaatt cttgtttgcc tttgaagatc 2940 cttcaaaccc aatgtctcaa ctcatctgga ctgttttacc ccaagggttc aggaatagcc 3000 cccatctatt tggccaggca ttagcccaag acttgagcca attctcctac ctggacactc 3060 ttgtccttcg gtacatggat gatttacttt tagccaccca ttcagaaacc ttgtgccatc 3120 aagccaccca agcactctta aatttccttg ctacctgtgg ctacaaggtt tccaaaccaa 3180 aggctcagct ctgctcacag caggttaaat acttagggct aaaattatcc aaaggcacca 3240 gaaccctcag tgaggaacgt atccagccta tactgggtta tcctcatccc aaaaccctaa 3300 agcaactaac agcgttcctt ggcataacag gtttctgcca aatatggatt cccaggtaca 3360 gcaaaatagc cagaccatta aatacacgaa ttaaggaaac tcaaaaagcc aatacccatt 3420 tagtaagatg gacacctgaa gcagaagtgg ctttccaggc cctaaagaag gcgctaacac 3480 atgccccagt gttaagcttg ccagtggggc aaaacttttc tttatatgtc acagaaaaaa 3540 acaggaatag ctctaggagt ccttacacag gtccaaggga tgagcttgca acccgtggca 3600 tacctgagta aggaaattga tgtagtggca aagggttggc ctcattgttt acaggtagtg 3660 gtggcagtag cagtcttggt atctgaagca gttaaaatga tacagggaag agatcttact 3720 gtgtggacat ctcacaatgt gaatagcaca ctcactgcta aaagacactt gtggctgtca 3780 gacaacaatt tacttaaata tcaggctcta ttacttgaag ggccaatgct gcaattgcac 3840 acttgtgcaa ctcttaaccc agccacattt cttccagaca acaaagaaaa gatagaacat 3900 aactgtcaac aagtaattgc tcaaacctgt gctgctcaag gggacctttt agaggttccc 3960 ttgactgatc ccgacctcaa cttgtatact gatgaaagtt cctttgtaga aaaaggactt 4020 tgaaaagtgg ggtatgcagt ggttggtgat aatggaatac tcgaaagtaa tccccttact 4080 ccaggaacta gtgctcagct ggcagaacta atagccctca ctcgggcacc agaattagga 4140 gaaggaaaaa gggtaaatat atatgcaaac tgtaagtagg cttacctagt cctccatgcc 4200 catgcagcaa tagggagaga aagggaattc ctaacttcca agggaacact tgtcaaacat 4260 caggaagcca ttaagagatt attattggct gtacagaaac ctaaagaggt ggcagtctta 4320 cactgctggg gtcatcagaa aggaaaagaa agggaaatag aagagaaccg ccaagcggat 4380 attgaagcca gaagagccgc aaggcaggac cctccattag aaatgcttac agaaggaccc 4440 ctagtatggg gtaatcccct ctgggaaacc aagccccagt actcagaaga agacatagaa 4500 tggggaacct cacaaagaca tagtttcctc ccctcaggat ggctagccac tgaagaagga 4560 aaatactttt gcctgcagct aaccaataga aattacttaa aacccttcac caaaccttcc 4620 acttatgcat tgatagcatg catcagatgg ccaaattatt atttactgga ccaggccttt 4680 tcaaaactat caagcagata gtcagggcct gtaaagtgtg ccaaagaaat aatcccctgc 4740 actgcaggcc atacaggaca atccctgtat gtttaacctc cttgttaagt ttgtctcttc 4800 cagaatcaaa gctgtaaaac tacaaatggc tcttcaaatg gagccccaga tgcagtccat 4860 gactaagatc tactgtggac ccctggaccg gcctgctagc ccatgctcca atgttaatga 4920 cattgaaggc acccctcccg aggaaatctc aactgcacaa cccctactat gccccaattc 4980 ggcaggaagc agttagagtg gtcgccagcc aacctcccca acagcacttg gttttcctgt 5040 ttagaggggg tactgagaga caggactagc tggatttctt aggccagcta aaaatcccta 5100 agcctagctg ggaaggggac tgcatccacc tttaaacagg gggcttgcaa cttagctcat 5160 acccaaccaa tcagagagct cactaaaatg ctaattaggc aaaaacagga ggtaaagaaa 5220 caaccaatca tctatcacct gagagcacaa caggagggac aatgatcggg atataaaccc 5280 aggcattcga gctggcaatg gctacggctc gagctgagct ttcactcgcc atccaccact 5340 gctgtttgcc gccgccaccg cagacccgct gctggcttcc atcccttcgg atccggcagg 5400 gtgtctgctg cattcctgat ccagcgaggt gcccattgcc actcccgatc gggctaaaga 5460 cttgccactg ttcctgcatg gctaagtgcc tgggttcgtt ctaatcaagc tgaacaccag 5520 tcattgggtt ccacagtttt cttcggtgac ccacggcttc taatagagct ataacactca 5580 ccgcatggcc caagattcca ttccttggaa tccgtaaggc caagaacccc aggtcagaga 5640 aaacgaggct tgccaccatc ttggaagcgg cctgctgcca ttttggaagt ggcccaccac 5700 catcttggga gctctgggag caaggacccc cggtaaca 5738 <210> 186 <211> 972 <212> DNA <213> Homo sapiens <400> 186 gtggggaaaa gaaagacaga tcagattgtt actgtgtctg tgtagaaaga agtagacata 60 ggagactcca ttttgttctg tactaagaaa aattcttctg ccttgagatg ctgttaatct 120 gtaaccctac ccctaaccct gtgctccctg aaacatgtgc tgtgtccact cagggttaaa 180 tggattaagg gttgtgcagg gtgtgctttg ttaaacaaat gctggaaggc agcatgctcg 240 ttaagagtca tcaccactcc ctaatctcaa gtacccagcg acacaaaata ctgcagaagg 300 ccacagggac ctctgcctag gaaagccagg tattgtccaa ggtttctccc catgtgatag 360 tctgaaatat ggcctcgtgg gaagggaaag acctgaccgt cccccagcct gacaccagta 420 aagggtctgc gctgaggagt attagtaaaa gaggaaggaa cgcctctttt cagttgagac 480 aagaggaagg cttctgtctc ctgcccgtcc cggggcaatg gaatgtctcg gtgtaaagcc 540 gattgtatat tccatctact gagatagggg aaaactgcct tagggctgga ggtgggacat 600 gatggcagca atactgctcc ttaaggcatt gagatgttta tgtatatgca tatcaaaagc 660 acagcagttt tttctttacc ttgtttatga tgcagagaca tttgttcacg tgtttacctt 720 ctgaccttct ctccactatt atcgtattat cctgccacgt ccccctctcc gggaaacgcc 780 cgataatgat caataaatac taagggaatt cagaggctgg tgccggcgtg gatcctccgt 840 atgctgaatg ccggtcccct gagccccttt ttctttctct atactttgtc tctgtgtctc 900 tttcttttcc tagtctctcg ttccacctaa cgagaaacat ccgcaggtgt ggaggggcaa 960 cccacccctt ca 972 <210> 187 <211> 963 <212> DNA <213> Homo sapiens <400> 187 gtggggaaaa gaaagagaga tcagattgtt actgtgtctg tatagaaaga agtagacgta 60 ggagactcca ttctgttctg tactaagaaa aattctgcct tgagattctg ttaatctgtg 120 accttacccc caaccctgtg ctccctgaaa cgtgtgctgt gtcaactcag ggttaaatgg 180 attaagggct gtgcagggtg tgctttgtta aacagatgct tgaaggcagc atgctcctta 240 agagtcatca ccactcccta atctcaagta cccagggaca caaacactgc ggaaggccgc 300 agggacctct gctgaggaaa gccaggtatt gtccaaggtt tctccccatg tgatagtctg 360 caatatggcc tcatgggaag ggaaagacct gaccgtcccc cagcccgaca cccgtaaagg 420 gtctgtgctg aggaggatta gtataagagg aaggcatgcc tcttgcagtt gagacaagag 480 gaaggcatct gtctcctgcc cgtccctggg caatggaatg tctcggtata aaacccaatt 540 tacgttccat ctactgagat agggaaaaac cgccttaggg ctggaggtgg gacatgcggg 600 cagcaatact gctttgtaaa gcattgagat gtttatgtgt atgcatatct aaaagcacag 660 cacttgattc tttaccttgt ctatgatgca aagacctttg ttcacgtgtt tgtctgctga 720 ctctctcccc gctattgtct tgtgaccctg acacatcccc ctctcggaga aacacccaca 780 aatgatcaat aaatactaag ggaactcaga ggctggcggg atcctccata tgctgaacgc 840 tggttccccg ggccccctta tttctttctc tatactttgt ctctgtgtct ttttcttttc 900 caagtctctc gttccaccta acgagaaaca cccacaggtg tggaggggca acccacccct 960 tca 963 <210> 188 <211> 6629 <212> DNA <213> Homo sapiens <400> 188 gtcaggcctc tgagcccaag cctgcacata tacatccaga tggcctgaag taactgaaga 60 atcacaaaag aagtgaaaat ggctggttcc tgccttaact gatgacatta ccttgtgaaa 120 ttccttctcc tggctcagag gctcccccac tgagcacctt gtgaccccct cccctgtctg 180 ccggagaaca accccctttg actataattt tccactacct acccaaatct tataaaatgg 240 ccccacccct atctctcttt gctgactctc tttttggact catcctcctg cacccaggcg 300 attaaaaagc tttattgctc acacaaagcc tgtttggtgg tctcttcaca tggacgcaca 360 tgacatttgg tgctgtgact cagatcgggg gacctccctc gggagatcaa tcccctgtcc 420 tcctgctatt tgctccatga gaaagatcca cctacgacat cgaatcctca gaccaaccag 480 cccaaggaac atctcaccaa ttttaaatca ggtaagcggc ttctttttac tctcttctcc 540 aacctctctc actatccctc aacttctttc tcctttcaat ttctgtgtca cccttcaatc 600 tctcccttca tttcaatccc tttccttttc tggtagagac agaggagaca cgttttatct 660 gtgaacccaa aactccagcg ccagtcatgg acttgggaag acagtcttcg cttggtgttt 720 aatgactgag gggatgcctg cttgattatt cacccacgtt tcagaggtgt ctgatcactg 780 tggggacgcc tgccttgatc cttcaccctt agtggcaagt atcactttcc tggggggggg 840 caagcacccc ccacccctta tctctgtgtc tctaccctct ctttactctg ggcttatctc 900 cttcactatg ggcaaccttc caccctccat tcctccatcc tctcccttag cctgtgttct 960 caagaactta aaacctcttc aactcacacc tgacctaaaa cctaaacacc ttattttctt 1020 ctgcaatgct gcttaacccc aacacaaact cgacaatggt tccaaatagc cagaaaatgg 1080 cacttttgat ttttacatcc tacaagatct agataattct tctcataaaa tgggcaaatg 1140 gtctgaggtg cctgacgtcc aggcattctt ttacacatca gtctcttcct aatctctgct 1200 cccagtgcga ctcatcccaa acctttcttc tttccctccc acctgtcccc acagtcccaa 1260 ccccaagcgt tgctttcaat cttccttttc taccgaccca tctgacctct cccttcatcc 1320 caagattgct cctcctcagg taactccccg ccaggctgag tcaggctcca attcttcctc 1380 agcttccgct cctccaccct ataatccttc tatcacctcc tctccccaca cccagtctgg 1440 cttacagttt tgttccgcga ctagccctcc cccacctccc aacaatttcc ttttaaaaat 1500 ggtggctaga gctaaaggca tagtcaaggt taatgctcct ttttctttat ccgacctctc 1560 ccaaatcagt tagcatttag gctttttttc gtcaaatatg aaaacccagc ccagtgcatg 1620 gctcatttgg caacaaccct gagacgcttt acagccctag accctgaaag gtcagaaggc 1680 cgtctcattc taaatatgca ttttattacc caatctgctc ccaacattaa ataaagctcc 1740 aaaaattaga ttctggccct caaaccccac aacaggactt aacctctcct tcaaggtgta 1800 caataataga gaagagttgc aattacttgc ctcttctctg agagaaagcc tagccacatc 1860 tccagcacac aagaacttca aaatgcctaa accacagtgg ccaggtgttc cttcaggact 1920 tcatccctca ggatcttgct tcacgtgctg gaaatctggc cactgggcca aggaatgcct 1980 gtggcccggg atccctccta agctgtatcc catctatgag ggactccact ggaaatcgga 2040 ctgtccaact cacctggcaa ccactcccag agcccctgga actctggccc aagactctct 2100 gactgactcc ttcccagatc ttctcagctt agcagctgaa gactgaagct gcccgatcac 2160 ctcagaagcc tcctggacca tcaaagatgc tttaggtaac tcttacagtg gagggtaagt 2220 ccgtcccctt cttaatcaat acagaggcta cccactccac attaccttct tttcatgggc 2280 ctgtttcctt tgcctccata actgttgtga gtattgatgg ccaggcttct aaacctctta 2340 aaactcccca actctggtgc caactaggac aacattcttt tatgcactcc cttttagtta 2400 tccccacctg cccagttccc ttattaggcc gagacatttt aactaaatta tctgcttccc 2460 tgactattac tgggctacag ccacacctca ttgccactct tttccccagt tcaaagcctc 2520 cttcgcatcc tccccttgta tctccccatc ttaatccaca ggtatgggat gcctctactc 2580 cctccctggc aaccacacgc ccattactat cccattaaaa cctaataacc cttaccccac 2640 tcaatgccaa tgccaatatc catcccacag gaggctttaa aaggattaaa gcctgttatc 2700 actcgcctgt tacagcatgg ccttttaaag cctataaact ctccctacaa ttcccccatt 2760 ttacctgtcc aaaaactgga caaatcttac aggttagttc aggatctgca ccttatcaac 2820 taaattgttt tgcctatcca ccctgtggtg cctaacacat acactctttt gtcctcaata 2880 ccttcctcca caactcacta ttccattctt gatcttaaag atgctttttt cactattccc 2940 ctgtacccct tgtcccagcc tctctttgct tttacctgga ctaaccctga cacccatcag 3000 tcccagcagc ttacctgggg tgtactacca caaggcttca gggacagccc tcattacttc 3060 agccaagctc tttctcataa tttactttct ttccacccct ctgcttctca ccttattcaa 3120 aatattgatg gccttctact ttgtagctcc tgctttgaat cttctcaaca agacaacctc 3180 ctgctccttc aacacttatt ctccaaggga tatccagtat ccccctccaa agctcaaatt 3240 tcttctctgt tacctacctc ggcataattc ttcataaaaa cacacatacc ctccctgcca 3300 atcatgtctg actgatgtct caaaccccaa ccccttctac aaaacaactc ctttccttcc 3360 tgggcatggt tagatacttt tgcctttgga tatctggttt tgccatctta acaaaaccgt 3420 tatataaact cacaaaagga aacctagctg accctgtaga tcctaaatct tttccccact 3480 cctcctttca ttccttgaag acagctttag agactgctcc cacactagct cttcctgact 3540 catcccaacc ctcttcatta cacacagtgg aagtgcaggg ctatgcagtg ggaattctta 3600 cacgaggact gggaccgcac cctgtagcct ttttgtccaa acatcttgac cttactgttt 3660 taggctggcc atcatgtctc catgcagcag ctgccactgc cctaatactt ttaaaggccc 3720 tcaaaatcac aaactatatt caactcattc tctacagttc tcataacttc caaaatctgt 3780 tttctttctc acacctgatg catatacttt ctgctccccg gctccttcag ctatattcac 3840 tctttgttga gtctcccaca attaccattg ttcctggcct ggacttcaat ccagcctccc 3900 acattattcc ggataccaca cctgaccccc atgactatat ctctctgatc cacctgacat 3960 tcacttcact tctccatatt tccttctttc ctgttcctca ccctgatcac acttggttta 4020 ttgatggcag ttccaccagg cctaattgcc actcaccagc aaaggcaggc tatgctatag 4080 tatcttccac atctatcatt gaggctactg ctctgccccc ctccactacc tgtcagcaag 4140 ccgaactcat tgccttaact tgagccctca ctcttgcaaa gggactatgc atcaatattt 4200 atactgactc caaatatgcc ttccgtatct ttcaccacca tgctgttata tgggcagaaa 4260 gaggtttcct cactacacaa gcgtcctcca tcattaatgc ctctttaata aaaactttac 4320 ttacaaagga agctggagtc attcactgca agggccatca aaaggtatca gatcccatca 4380 ctcagggcaa tgcttatgct gataaggtag ctaaagaagc agctagcatt ccaacttctg 4440 tccctcatgg ccagtttttc tccttctcat tgttcactcc cacctactct ttcactgaaa 4500 cttccaccta tcaatctctt cccacacaag gcaaatggtt cttggaccaa aggaaatatc 4560 tccttccagc ctcacaggcc cattctattc tgttgtcatt tcataacctc ttccacgtag 4620 gttacaagcc gctagcctgc ctctcagagc ctctcatttc ctttccatcg tggacaccta 4680 tcctcaagga aatcacttct cagtgttcta tctgctattc tactgctcct cagggattgt 4740 tcaggccccc tcccttccct acacatcaag ctcggggatt tgcccctgcc caggactggt 4800 aacctgactt tactcacatg ccctgagtca agaaactaaa atacctctta gtctaggtag 4860 acactttcac tgaatgggta gaggcctttc ccacagggtc tgagaaggcc accacggtca 4920 tttcttccct tctgtcagaa gtaattcctc ggtttggcct tcctacctct atacagtctg 4980 ataacaaacc agcctttatt agtcaaatca cccaagcagt ttctcaggct ctcagtattc 5040 agtgaaacct tcatacccct taccgttctc aatcttgagg aaaggtaaaa cggactaatg 5100 gtcttttaaa aacacacctc accaagctca gccttcaact taaaaaggac tgggcaatac 5160 ttttaccact tgcccttctc agaattcggg cctgtcctcg ggatgctaca gggtgcaacc 5220 catttgaatt cctgtacgaa cgctcctttt tattaggccc tggtctcatt ccagatacca 5280 acccaacttg gactgcgccc caaaaacttg tcatccctac tatcttctgt ctagtcatac 5340 tcctattcac tattctcaac tactcttaaa tgccctgctc ttgtttacac tgccagttta 5400 cactgtttct ccaagccatc acagctaata tctcctggtg ctatctccaa accgccactc 5460 ttaactgcct cttagagtgg acagatgatc tttgctgaca aggtacacta caatactctc 5520 accctgatga aatcctattc tttactttta tactcactgt tattcttgtt cctgttctta 5580 tgccaccctc tacctctccc cagctatctc caccgcacta tcaatctcac tcactctctc 5640 ctagccattt ataatccttc tttaacgaac aattgctggc tttgcatttc tctttcctcc 5700 aaaatctcgg aggcctcgac ttactcactg ctaaaaaaaa agaggactct gtatgttttt 5760 aagtgaaaag tgttgttttt acctaaatca atctggcctg gtgtatgaca acataaaaaa 5820 aactcaagga tagagcccag aaactcacca accaagcaag taattacgct gaaccccctt 5880 gggcactctc taattggatg tcctgggtcc tcccaattct tagtccttta atacctgttt 5940 ttctctttct cttattcaga ccttgtgtct ttcatttagt ttctcaattc atacaaaacc 6000 atatccaggc catcacgcat cattctatat gacaaatgtt tcttctaaca accccacaat 6060 atcacccctt accacaaaat cttccttcag cttaatctct cccactctag gttcccatgc 6120 caccccaatc ccactcgaag cagccctgag aaacatcatc cattatctct ccatatcacc 6180 cccaaaaatt ttcgctgccc caacacttta ccactatttc gttttatttt tcttattaat 6240 ataagaagac aggaatgtca ggcctctgag cccaagcctg cacatataca tccagatggc 6300 ctaaaggcct aaaagtaact gaagaatcac agaagaagtg aaaatggccg gttcctgcct 6360 taactgatga cattaccttg tgaaattcct tctcctggct cagaggctcc cccactgagc 6420 accttgtgac ccccacccct gcctgccaga gaacaacccc ctttgactat aattttccac 6480 tacctaccca aatcctataa aatggcccca ccccatctcc cttctctgac tctctttttg 6540 gacacagccc gcctgcaact aggtgattaa aaactttatt gctcacacaa agcctgtttg 6600 gtggtctctt cacacagatg cacgtgaaa 6629 <210> 189 <211> 5856 <212> DNA <213> Homo sapiens <400> 189 gccaggcctc tgagcccaag ccaagccatc acatcccctg tgacttgcac atatacgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa tatgccctgc cccaccttaa 120 ctgatgacat tccaccacaa aagaagtgta aatggccagt ccttgcctta agtgatgaca 180 ttaccttgtg aaagtccttt tcctggctca tcctggctca aaaagcaccc ccactgagca 240 ccttgcgacc cccactcctg cctgccagag aacaaccccc ctttgactgt aattttccct 300 tacctaccca aatcctataa attgccccac ccctatctcc ctttgctgac tctcttttca 360 gactcagccc acctgcaccc aggtgattaa aagctttatt gctcacacaa agcctgtttg 420 gtggtctctt cacacggaca cacatgaaat ttggtgccgt gactcggatc gggggtcctc 480 ccttgggaga tcaatcccct gtcctcctgt tctttgctcc gtgagaaaga tccacctacg 540 acctcaggtc ctcagaccga ccagcccaac gaacatctca ccaattttaa atcaggtaag 600 cggcctcttc ttactctctt ctccaacctc tctcactgtc cctcaaccac tttctccttt 660 ccactcttca atctctccct tctcttaatt tcaattcctt tcattttctg ggagagacaa 720 aggagacacg ttttatctgt ggatccaaaa ctccagcacc ggtcacggac tgggaaggca 780 gccttccctt ggtgtttaat cattgcaggg acgcctgatt attcacccac gtttcaaagg 840 tgtcagacca tgcagggatg cctgccttgg tccttcaccc ttagcggcag gtcccgcttt 900 tctgggaaag gggcaagtac cccaacccct tctctccttg tctctacccc ttctctgctt 960 ttctggggga ggggcaagta cccctcaacc ccttctcctt cacccttagc ggcaagtccc 1020 gcttttctgg gggaggggca agtacccttc aaccccttct ccttcactct tagtggcaag 1080 tcccactttt ctagaggagg ggcaagtacc ccaacctcgt atctctgcac cccaatccct 1140 tatttctgtg ccccgacccc ttatttctgt gcccctaccc cttatttcca cgcctcatcc 1200 cttatttcca tgccccatcc cttatttctg tgccccatcc cttatttccg tgccccaacc 1260 ccttatctct gtgccccaac ccctttttcc acttttctgg aaggtaagaa cccccaaacc 1320 tcttccctct gtttctctac tctcttctct aggcttgctt ccttcactat aggcaacctt 1380 ccaccctcca ttcctccttc tactcccttg gcctgtgttc tcaaaaactt aaaacctctt 1440 caactcacac ctgacataaa acctaaatgc cttattttct tctgcaatgc cgcctgaccc 1500 caatacaaac tcaacagcag ttccaaatag ccagaaaatg gcactttgac tttttccatc 1560 ctacaagatc taaataattc ttgtcataaa ataggcaaat ggtctgaggt gcctgacatc 1620 caggcattct tttacacatc agtcccttcc cagtctctgt gcccagtgca actcgtccca 1680 aatcttccct ctttccctcc cgcctgtccc ctcagtccca acaccaagcg tcgctgagtc 1740 tttctaatct tccttttcta cagacccatc tgacctctcc cttcctcccc aggctgctcc 1800 tcgccaggcc gagctaggtc ccaattcttc ctcagcctct gctcctccac cctataatct 1860 ttttatcacc tcctctcctc acacctggtc cagcttacag tttcgttccg tgagtagcct 1920 tccccctcct gcccggcaat ttactcttaa aaaggtggct ggagctaaag gcatagtcaa 1980 ggttaatgct cctttttctt tatcccaaat cagatagcgt ttaggctctt tttcatcaaa 2040 tataataatc cagctcagtt catgacttgt ttggcagcaa ccctgagaca ctttacagcc 2100 ctagacccta aaagctcaaa aggccgtctt attctcaaaa taatgtcaat ctgctcctga 2160 cattaaataa aactccaaaa attaaattcc ggccctcaaa ccccacaaca ggatttaatt 2220 aacctcacct tcaaggtgta caataataga aaaaagttgc aattccttgc ctccactgtg 2280 agacaaaccc cagccacatc tccagcacac aagaacttcc aaatgcctga aactcagcgg 2340 ccaggcgttc ctccagaacc tcctccccca ggagcttgcc acaagtgcca gaaatctgac 2400 caccaggcca aggaatgcct gcagcccagg attcctccta agccgtgtcc catctgtgtg 2460 ggaccccact gaaaatcgga ctgttcaact cacctggcag ccactcccag aggccctgga 2520 actctggccc aaggctctct gactgactcc ttcccagatc ttctcggctt cgcagctgaa 2580 gactgacact gcccgatggc ctcggaagcc ccctagacca tcacagacgc agagcttcgg 2640 gtaactctca cagtggaagg caagcctgtc cccttcttaa tcaatacgga ggctacccac 2700 tccacattac cttcttttca agggcctgtt tcccttgcct ccataactgt tgtgggtatt 2760 gacggccagg cctctaaacc tcttaaaact ccccaactct ggtgccaact tagaaaatac 2820 tcttttaagc actccttttt agttatcccc acctgcccag ttcccttatt aggctgagac 2880 actttaacta aattatctgc ttccctgact atccctggac tacagctata tctcattgcc 2940 acccttcttc ccaatccaaa gcctcctttg cgtcctcctc ttgtatcccc ccaccttaac 3000 ccacaagtat aagatacctc tactccctcc ttggcgaccg atcatgcacc ccttaccatc 3060 tcattaaaac ctaatcaccc ttaccccact caacgccaat atcccatccg gcagcacgct 3120 ttaaaaagat taaagcctgt tatcactcgc ctgctatagc atggcctttt aaagcctata 3180 aactctcctt acaattcccc cattttacct gtcctaaaac cagacaagcc ttacaagtta 3240 gttcaggatc tgtgccttat caaccaaatt gttttgccta tccaccctgt gatgccaaac 3300 ccatatactc tcctatcctc aatacctgtc tctacaaccc attattctgt cctagatctc 3360 aaacatgctt tctttactat tcctttgcac ccttaatccc agcctctctt cactttcact 3420 tggactgacc ctgacaccca tcaagctcag caaattacct aggctgtact gctgcaaagc 3480 ttcacagaca gcccccatta cttcaatcaa gcccaaattt cttcctcatc tgttacctat 3540 ctcggcataa ttctcataaa aacacacgtg ctctccctgc caatcgtgtc cgactgatct 3600 ctcaaaccca agcaccttct acaaaacaac aactcctttc cttcctaggc atggctagca 3660 tggtcagaat tcttacacaa gagccaggac cacaccctgt agcctttctg tccaaacaac 3720 ttgaccttac tgttttagcc tagccctcat gtctgcgtgc agcggctgcc gctgctttaa 3780 tacttttaga ggccctcaaa atcacaagct atgctcaact cactctctac agttctcata 3840 acttccaaaa tctattttct tccccatacc tgacgcatat actttctgct ccccggctcc 3900 ttcagctgta ctcactcttt gttgagtctc ccacaattac cgttgttccc ggcccagact 3960 tcaatccggc ctcccacatt attcctgata ccacacctga cccccatgac tatctctctg 4020 atccacctga cattcacccc atttccccaa atttccttct ttcctgttcc tcaccctgat 4080 cacgcttgat ttattgacgg cagttccacc aggcctaatc gccacacacc agcaaaggca 4140 ggttatacta tagtacaagc cactagcccg cctcttagaa cctctcattt cctttccatc 4200 gtggaaatct atcctcgagg aaataacttc tcagtgttcc atctgctatt ctactactcc 4260 tcagggatta ttcaggcccc ctcccttccc tacacatcaa gctccaggat ttgccccacc 4320 caggactggc aaattagctt tactcaacat ggcctgagtc agataactaa aatacctctt 4380 agtctaggta gattctttca ctggataggt agaggccttt cctacagggt ctgagaaggc 4440 cactgaggtc atttcttccg ttctgtcaga cataattcct cagtttagcc ttcccacctc 4500 tatacagtct gataacagac gagcctttat tagtcaaatc agccaagcag tttttcaggc 4560 tcttagtatt cagtgaaacc tttatatccc ttacggtcct ccgtcttcaa gaaaagtaga 4620 atggactaaa ggtcttttaa aaacacacct caccaagctc agccaccaac ttaaaaagga 4680 ctagacaata cttttaccac tttcccttct cagaattcag gcctgtcctc ggaatgctac 4740 agggtacagc ccatttaagc tcctgtatag atgctccttt ttattaggcc ccggtctcat 4800 tccagacacc agaccaactt agactgtgcc ccaaaaatct tgtcatccct actatcttct 4860 gtctagtcat actcctattc accgttctca actactcata ccctgctctt gtttacactg 4920 ccagtttaca ctgtttttcc aagccatcac agctgatatc tcctggtgct atccccaaac 4980 tgccactgtt aactcttgaa gtaaataaat aatctttgct ggcaggacta tgctgtatct 5040 ccttaggcac tctctaatca gatatcctga gtcgtcccaa ttcttagacc ttttatacct 5100 gtttttctcc ttctgttatt ccatttagtt tctcaattca tccaaaaccg tatctaggcc 5160 atcaccaatc attctataca acaaatgttt cttctaacat ccccacaata tcacccctta 5220 ccacaagacc tcccttcagc ttaatctctc ccactctagg ttcccacgct gcccctaatc 5280 ctgcttgaag tagccctgag aaacatcacc cattctctct ccaaaccacc ccccaaaaat 5340 ttttgccgcc ccaacacttc aatactattt tgttttattt ttcttattaa tagaagaagg 5400 caggaatgtc aggcctctga gcccaagccc agccatcaca tcccctgtga cttgcacata 5460 tacgcccaga tggcctgaag taactgaaga atcacaaaag aagtgaatat gccctgcccc 5520 accttaactg atgacattcc accacaaaag aagtgtaaat ggccggtcct tgccttaagt 5580 gatgacatta ccttgtgaaa gtccttttcc tggctcatcc tggctcaaaa agcaccccca 5640 ctgagcacat tgcgagcccc actcctgccc gccagagaac aacccccctt tgactgtaat 5700 tttcccttac ctacccaaat cctataaatg gccccacccc tatctccctt tgctgactct 5760 cttttcggac tcagcccacc tgcacccagg tgattaaaag ctttattgct cacacaaagc 5820 ctgtttggtg gtctcttcac agggacgcac atgaaa 5856 <210> 190 <211> 362 <212> DNA <213> Homo sapiens <400> 190 tgggtagcta ggcagacatg agcagggcgg gaaaggcccc ctaccccagg aatgtcaggc 60 aaccatcagg tgatggtcag gtggttgttc gactgtctct ctaaaataat aattggtcac 120 agctgggagg tgccagggaa aggcagcctc ccagtagatg ggaaacacct gaaactggta 180 ccagccgctt cctgataaga tctcaggagt tgggtgagtg ggccccagcc tgttcactaa 240 gaggcaaaat ggtggagttt aactggcaca tgaccttcct ctaggaacat tcaactggta 300 agggaaaaat gcctcaaatg agcacgtaca caatcttcag taaacacatt gtgcatatgg 360 cc 362 <210> 191 <211> 3863 <212> DNA <213> Homo sapiens <400> 191 ttgctaactt gcgtgctaga aggactaagg aaaactagga agaagcctat gaattattca 60 gtgatgtcca ctataacaca gggaaaggaa gaaaatccta ctgcctttct agagagacta 120 agggaggcat tgagaaagca tacctccctg tcacctgact ctactgaagg ccaactaatc 180 ttaaaggata agtttatcac ccagtcagct acagacatta gaaaaaaact tcaaaagtcc 240 accttaggcc cggagcaaaa cttagaaacc ctattgaact tagcaacctt ggttttctat 300 aatagagatc aggaggagcg gtggaacagg acaaacggta taaaaaaaaa ggccaccgct 360 ttagtcatgg ccctcaggca agtggacttt ggaggctctg gaaaagggaa aagctgggca 420 aatcgaatgc ctaatagggc ttgcttccag tgcggtctac caggacactt taaaaaagat 480 tgtccaaata gaagtaagcc gcccccttgt ccatgcccct tatgttgagg gaatcactgg 540 aaggcccact gccccagggg atgaaggtcc tctgagtcag aaaccactaa ccagatgatc 600 cagcagcagg actgagggtg cctggggcaa gtgccagccc atgccatcac cctcacagag 660 ccccaggtat gcttcaccat tgagggccag gaggttaact gtctcctgga cactggcaca 720 gccttctcgg tcttactctc ctgtcccgga caactgtcct ccagatctgt cactatccga 780 ggggtcctag gacagccagt cactagatac ttctcccagc cactaagttt tgactgagga 840 gctttactct tttcacacgc ttttctaatt atgcctgaaa gccccactcc cttggttagg 900 gagagacatt ctagcaaaag caggggccat tatacacctg aacataggag aaggaacacc 960 catttgttat cccctgcttg aggaaggaat taatcctgaa gtcttgccaa cagaaggaca 1020 atatggatga gcaaagaatg ctcgtcctgt tcaagttaaa ctaaaggatt ctgcctcctt 1080 tccctaccaa aggcagtacc cccttagacc caaggctcaa caaggactcc aaaagattgt 1140 taaggaccta aaagcccaag gcctagtgaa atcatgcaat agcccctgca atactccaat 1200 tttaggagta cagaaaccca gcagacagtg gaggttagtg caagaactca ggattatcaa 1260 tgaggccgtt gtccctctag acccagctgt acctaaccct catactctgc tttcccaaat 1320 accagaggaa gcagtgtggt ttacagtcct ggaccttaag gatgcctttt tcagcatccc 1380 tgtacatcct gactctcaat tcttgtttgc ctttgaagat ccttcaaacc caacgtctca 1440 actcacctgg actgttttac cccaagggtt cagggatagc ccccatctat ttggccaggc 1500 attagcccaa gacttgagcc aattctcata cctggacact cttgtccttc ggtacatgga 1560 tgatttactt ttagctgcca gttcagaaac cttgtgccat caagccaccc aagcgctctt 1620 aaatttcctt gctacctgtg gctacaaggt ttccaaacca aacgctcagc actgctcaca 1680 gcaggttaaa tacttagggc taaaattatc caaaggtacc aaggcccttg gtgaggaacg 1740 tatccagcct atactggctt accctcatcc caaaacccta aagcaactaa gagggttcct 1800 tggcataaca ggtttctgcc aaatatggat attcccaggt acagcaaaat agccagacca 1860 ttatatacac taattaagga aactcagaaa gccaataccc atttagtaag atggacacct 1920 gaagcagaag cagctttcca ggccctaaag aaggccctaa cccaagcccc agtgttaagc 1980 ttgccaacag agcaagactt ttctttatat gtcatagaaa aaacaggaat agctctagga 2040 gtccttacac agatccaagg gacaagcttg caacccatgg catacctgag taaggaaatt 2100 gatgtagtgg caaagggttg gcctcattgt ttacgggtag tagcggcagt agcagtctta 2160 gtatctgaag cagttaaaat aatacaggga agagatttta ttgtgtggac atcttatgat 2220 gtgaatggca tactgactgc taaaggagac ttgtggctgt cagacaaccg tttacttaaa 2280 tatcaggctc tattacttga agggccagtg ctgtgactgc atacttgtgc aactcttaat 2340 ccagcaacat ttcttccaga caataaagaa aagatagaac ataactgtca acaagtaatt 2400 gctcaaacct acgctgctcg aggggacctt ttagaggttc ccttgactga tcccaacctc 2460 agcttgtata ctgatggaag ttcctttgta gaaaagggac tttgaaaagc gaggtatgca 2520 gtggtcagtg ataatggaat acttaaaagt aatcccctca ctccaggaac tagtgctcag 2580 ttggcagaac taatagccct cacttgggca ctaaaattag gagaaggaaa aaaggtaaat 2640 atatatacag actctaagta tgcttaccta gtcctccatg cccatgcagc aatatggaga 2700 gaaagggaat tcctaacttc caagggaaca cctattaaac atcaggaagt ctttaggaga 2760 ttattattgg ctgtacagaa acctaaagag gtggcagtct tacactgccg gggtcatcag 2820 aaaggaaagg aaaggaaaat agaaggaaac caccaagtgg acattgaagc caaaagagcc 2880 acaaggcagg accctccatt tgaaatgctt atagaaggac ccctagtatg gggtaatccc 2940 ctccgagaaa ccaagcccca ctactcagca ggaaaaatag aatagggaac ctcatgagga 3000 catactttcc tcctctccag atggctagcc accgaagaag gaaaaatact tttgcctgca 3060 gctaaccaat agaaattact taaaaacctt caccaaacct ttcagttagg cattgatagc 3120 acccatcaga tggccaaatt attatttact ggaccaggcc ttttcaaaac tatcaagcag 3180 atagtcaggg cctgtgaagt atgccaaaga aataatcccc tgcactgcag gccatacatt 3240 tcaatccctg tatctttaat ctccttgtta agtttgtctc ttccagaatc aaagctgtaa 3300 aactaccaat cgttcttcaa atggagcccc agatacagtc catgactaaa atctgccaca 3360 gacccctgga ctggcctgct agccaatgct ctgatgttaa tgacatcaaa ggcactcctc 3420 ccgaggaaat ctcaactgca caacccctac tatgccccaa ttcagcagga agcagttaga 3480 acggtcgtca gccatcctct ccaacagcac ttgggttttc ctgttgagag cggggactga 3540 gagacaggac tagctgggtt tcctaggccg attaagaatc cctaagccta gctgggaagg 3600 tgaccacgtc cacctttaaa catggggctt gcaacttagc tcacacccga ccagtcagat 3660 agtaaagaga gctcactaaa acgctaatta ggctaaaaca ggaggcaaag aaatagccaa 3720 tcatctatca cctgagacca cagggggagg gacaatgatc gggatataaa cccaggcatt 3780 cgagctggca acagctaccc tctttgggtc ccctccctct gtatgggagc tctgtcttcc 3840 ctctattaaa tcttgcaact gca 3863 <210> 192 <211> 968 <212> DNA <213> Homo sapiens <400> 192 gtggggaaaa gaaagggaga ccagattgtt actgtgtctg tgtagaaaga agtagacata 60 ggaggctcca ttttgttctg tactaagaaa aattcttctg cattgagatg ctgttaatct 120 gtaacactac ccccaaccct gtgctccctg aaacacgtgc tgtgtcaact cagggttaaa 180 tggattaagg gctgtgcagg gtgtgctttg ttaaacaaat gcttgaaggt agcatgcttg 240 ttaagagtca tcaccactcc ctaatctcaa accacttcct aatctcaagt acccagagac 300 acaaaccact gaggaaggcc gcagggatct ctgcctagga aagccaggta ttgtccaagg 360 tttctcccca tgtgatagcc tgagatatgg cctcgtggga agggaaagac ctgaccgtcc 420 cccagcccga cacccgtaaa gggtctgtgc tgaggaggat tagtaaaaga ggaagtaaca 480 cctccttgcg gttgagacaa gaggaaggca tctgtctcct gctcgtccct gggcaatgga 540 atgtctcggt gtaaaacctg attgtatatt ccatctactg agatagggga aagccacctt 600 agggctggag gtgggacatg cgggcagcaa tactgctctt taaggcattg agatgtttat 660 gtgtatacat atccaaagca cagcacttaa ttctttacct tgtttatgat gcagagacct 720 ttgttcacgt gtttacctgc tgaccttctc tccactatta tcctatgatc ctgccacatc 780 cccctctccg ggaaacgccc aataatgatc aataaatact aagggaactc agaggctggc 840 gtggatcctc cgtatactga acgctggtca gctgggccca gttttctttc tctatacttt 900 gtctctgtgt ctcttgttcc acctaacgag aaacgcccac aggtgtggag gggcaaccca 960 ccccttca 968 <210> 193 <211> 5809 <212> DNA <213> Homo sapiens <400> 193 gtcaggcctc tgagcccaag ccaagccatc gtatcccctg tgacctgcac ctgtacgccc 60 agatggcctg aagtaactaa agaatcacaa aagaagtgaa tatgccctgc cccaccttaa 120 ctgatgacat tccaccacaa aagaagtgta aatggccagt ccttgcctta actgatgaca 180 ttaccttgtg aaagtccttt tcctggctca tcctggctcc aaaagcaccc ccactgagca 240 ccttgcgacc cccactcctg cccactgagc accttgcaac ccccactcct acccgccaga 300 gaacaaaccc ccttggactg taattttcct ttacctaccc aaatcctata aaacggcctc 360 acccttatct cccttcactg acccttttcg gactcagcct gcctgcaccc aggtgaagtg 420 agcaacagcc atgttgctca cacaaagcct gtttggtggt ctcttcacat ggacgcgcat 480 gaaatttggt gccgtgactc ggatcggggg acctcccttg ggagatcaat cccctgtcct 540 cctgctcttt gctccgtgag aaagatccac ctacgacctc aggtcttcag accgaccagc 600 ccaagaaaca tctcaccaat ttcaaatccg gtaagcggcc tctttttact ctcttctcca 660 acctccctca ctatccctca acctctttct cctttcaatc ttggcgccac acttcaatct 720 ctcccttctc ttaatttcaa ttcctttcat tttctggtag agacaaaaga gacatgtttt 780 atccgtgaac ccaaaactcc ggcgccagtc acggactggg aaggcagcct tcccttggta 840 tttaatcatt gcagggacgc ctctctgatt atacactcac gtttcaaggg tgtcagacca 900 cgcagggacg cctgccttgg tccttcaccc ttagcggcaa gtcccgcttt cctggggcag 960 gggcaagtac ccctcaaccc cttctccttc acccttagcg gcaagtcccg ctttcctagg 1020 gggcaagaac cccccaatca cttatttcca caccccaacc tcttatctct gtgccccaat 1080 cgcgtatttc cacaccccaa cctcttatct ctgcacccca atcccttatt tccgcaccct 1140 gacctcttat ctctgtgccc caatccctta tttccgtgtc ccagcccttt ctctgctttt 1200 ctggagggga agaaaccccc accccttctc cgtgcctcta ctcttttctc tgggcttgcc 1260 tccttcacta tgggcaagct tccaccttcc attcctcttt cttctccctt agcctgtatt 1320 cttaagaact taaaacctct tcaattctca cctgacctaa aatctaagag tcttattttc 1380 ttctgcaatg ccgcttgacc ccaatacaaa ctcaagagta gttccaaata gccagaaaac 1440 ggcactttca atttttccac cctacaagat ctaaataatt cttgtcgtaa aatgggcaaa 1500 tggtctgagg tgcctgaagt ccaggcattc ttttacacat cagttccttc ctagcctctg 1560 tgcccagtgc aactcgtccc aaatcttcct tctttccctc cctcctgtcc cctcagtacc 1620 gaccccaagc gtcgctgagt ctttctaatc ttccttttct acagacccat ctgacctctc 1680 ccctcctcga caggccaagc taggccccaa ttcttcctca gcctccgctc ctccaccctg 1740 taatcttttt attgcctccc ctcctcacac ctggtctggc ttacagtttc cttctgtgac 1800 tagccctccc cgacctgccc agcaatttac tcttaaaaag gtggctggag ccaaaggcat 1860 agtcaaggtt aatgctcctt tttctttatc ccaaatcaga tagcgtttag gctctttttc 1920 atcaaatata aaaatccagc ccagttcatg gctcgtttgg cagcaaccct gagacacttt 1980 acagccctag cccctaaaag gtcaaaaggc cgtcttattc tcaatataca ttttattacc 2040 caatctgctc ccgacattaa ataaaactcc aaaaactaga atctggccct caaaccccac 2100 aacaggactt aattaacctc accttcaagg tgtgcaataa cagaaaaaag ttgcaattcc 2160 ttgcctccac tgtgagacaa acctcagcca catctccagc acacaagaac ttccaaacgc 2220 ctgaactgta gcagccaggc gttcctccag aacctcctcc cccaggaact tgctacacat 2280 gccggaaatc tggccactgg gccaaggaac acccgcagcc caggattcct cctaagccac 2340 gtcccatctg tgtgggaccc cactgaaaat tggactgttc aactcacctg gcagccactc 2400 ccagagctcc tggaactctg gcccaaggct ctctgactga ctccttcttg gcttaccggc 2460 tgaagactga cactgcccga ttgcctcgga agccccctag accatcacgg acgccgagct 2520 tcgggtaact ctcacagtgg aaggtaagcc cgtccccttc ttaatcaata cggaggctac 2580 tcactccaca ttacgttctt ttcaagggtc tgtttccctt gcctccataa ctgttgtggg 2640 tattgatggc caggcttcta aacctcttaa aactccccat ctggtgccaa cttagacaat 2700 actcttttaa gcactccttt ttagttgtcc ccacctgccc agttccctta ttaggctgag 2760 acactttaac taaattatct gcttccctga ctattcctgg actacagcta tatctcattg 2820 ctgctcttct tcccaatcca aagcctcctt tgggtcctcc tcttgtatcc cccaacctta 2880 acccacaagt ataagatacc tctactccct ccttggcgac caatcatgca ccccttacca 2940 tctcattaaa acctaatcac ccttacccca ctcaacgcca atatcccatc ccacagcaca 3000 ctttaaaaag attaaagcct gttatcactc gcctgctaca gcatggcctt ttaaagccta 3060 taaactctcc ttacaattcc cccattttac ctgtcctaaa accagacaag ccttacaagt 3120 ttgttcagga tctgcgcctc atcaaccaaa ttgttttgcc tatccacccc gtggtgccaa 3180 acccatatac tctcctatcc tcaatacctg cctctacaac ccattattct gttctagatc 3240 tcaaacatgc tttctttgct attcctttgc acccttaatc ccagcctctc ttcgctttca 3300 cttggactga ccctgacacc catcaagctc atcaaattac ctaggctgta ctgccgcaaa 3360 gcttcacaga cagcccccat tacttcaatc aagcccaaat ttcttcctca tctgttacct 3420 atcttggcat aattctcata aaaacacacg tgctctccct gccaatcgtg tccgactgat 3480 ctctcaaacc caagcacctt ctacaaaaca acaactcctt tccttcctag gcatggttag 3540 cgaggtcaga attcttacac aagagccagg accacaccct gtagcctttc tgtccaaaca 3600 acttgacctt actgttttag cctagccctc atgtctgcat gcagctgctg ccgctgcatt 3660 aatactttta gaggccctca aaatcacaaa ctatgctcaa ctcactctct acagttctca 3720 taacttccaa aatctatttt cttcctcata cctgatgcat atactttctg cttcccggct 3780 ccttcagcta taccccactc tttgttgagt ctcccacaat taccgttgtt cctggcccag 3840 acttcaatcc tacctcccac attattcctg ataccacacc tgacccccat gactgtatct 3900 ctctgatcca cctgacatta accccatttc cccaaatttc tttctttcct gttcctcacc 3960 ctgatcacgc ttgatttatt gatggcagtt ccaccaggcc taatcgccac acaccagcaa 4020 aggcagatga tgctatagta caagccacta gcccgcctct tagaacctct catttccttt 4080 ccatcatgga aatctatcct caaagaaata acttctcagt gttccatctg ctattctgct 4140 cagtgttcca tctgctattc tactactcct cagggattat tcaggccccc tcccttccct 4200 acacatcaag ctcgaggatt tgccccaccc aggactggca aattagcttt actcaacatg 4260 cccttagtca gataactaaa atacctctta gtctaggtag ataatttcac tggataggta 4320 gaggcctttc ctacagggtg tgtacagggt gtgagaaggc caccgcagtc atttattccc 4380 ttctgtcaga cataattcct cagtttagcc ttcccacctc aatacagtct gataacagac 4440 gagcctttat cagtcaaatc agccaagcag tttttcaggc tcttagtatt cagtgaaacc 4500 tttatatccc ttacggtcct ctgtcttcaa gcaaagtaga atggactaaa ggtcttttaa 4560 aaacacacct caccaagctc agccaccaac ttaaaaagga ctggacaata cttttaccac 4620 tttcccttct cagaattcag gcctgtcttc agaatgctac agggtacagc ccatttaagc 4680 tcctgtatag acgctccttt ttattaggct ccagtctcat tccagacacc agaccaactt 4740 agactgtgcc ccaaaaaacc tgtcatccct actatcttct gtctagtcat actcctattc 4800 accgttctca actactcata catgccctgc tcttgtttac actgctggtt tacactgttt 4860 ttccaagcca tcacaactga tatctcctgg tgctatcccc aaactgccac tcttaactct 4920 tgaagtaaat acataatctt tgctggcagg actatgctga atctccttag gcactctcta 4980 atcagatatc ctgagtcgtc ccaattctta gaccttttat acctgttttt ctccttctgt 5040 tattccattt agtttctcaa ttcatccaaa accgtatcca ggccatcacc aatcattcta 5100 tacgacaaat gtttcttcta acatccccac aatatcaccc cttaccacaa gacctccctt 5160 cagcttaacc tctcccactc taggttccca cgccgcccct aatcccgctt gaagcagccc 5220 tgagaaacat cgaccattct ctctccatac cacccccaaa aaattttcac cgccccaaca 5280 cttcaacact attttgtttt atttttctta ttaagaaggc aggaatgtca ggcctctggg 5340 cccaagccaa gccatcacat cccctgtgac ctgcacctat aagcccagat ggcctgaagt 5400 aactaaagaa tcacaaaaga agtgaatatg ccctgcccca ccttaactga tgacattcca 5460 ccacaaaaga agtgtaaatg gccggtcctt gccttaactg atgacattac cttgtgaaag 5520 tccttttcct ggctcatcct ggctccaaaa gcatccccac tgagcacctt gcgaccccca 5580 ctcctgccca ctgagcacct tgcaaccccc actcctaccc gccagagaac aaaccccctt 5640 ggactgtaat tttcctttac ctacccaaat cctataaaac ggccccaccc ttatctccct 5700 tcgctgactc tcttttcgaa ctcagcccgc ctgcaaccag gtgaaataaa cagccatgtt 5760 gctcacacaa agcctgtttg gtggtctctt cacacggacg cacatgaaa 5809 <210> 194 <211> 954 <212> DNA <213> Homo sapiens <400> 194 gtggggaaaa gagagatcag attgttactg tctctgtgta gaaagaagta gacagaggag 60 actccatttt gttctgtact aagaaaaatt cttctgcctt gagatgctgt taatctgtaa 120 ccttatcccc aaccctgtgc tccctgaaac atgtgctgtg tcaactcagg gttaaatgga 180 ttaagggctg tgcaagatat gctttgttaa aacaaatgct tgaaggcagc atgctcgttt 240 taagagtcat caccactccc taatctcaag tatccgggga cacaaacact gcggaaggcc 300 acagggacct ctgcctagga aacccaggta ttgtccaagg tttctcccca tgtgatagtc 360 tgaaatatgg cctcgtggga agggaaagac ctgaccgggg tcccccagcc tgacaccctg 420 tgctaaggag gattagtaaa agaggaagga acgcctcttt gcagttgaga caagaggaag 480 gcatctgtct ccagccagtc cctgggcaat ggaatgtctc agtgtaaaac ccaattgtat 540 gttccatcta ctgagacagg ggaaaaccgc ctcaggggtg gaggtgggac atgcgggcag 600 caatactgct ctttaaggca ttgagatgtt tatgtgtatg cacatctaaa gcacagcact 660 taattcttta ccttgttcat gatgcagaga cctttgttca cgtgtttatc tgctgacctt 720 ctctccacta ttatcctatg accctgccac atccccctct ccgagaaaca cccaagaatg 780 atcaataaat actaagggaa ctcagaggcc ggcgggatcc tctgtatgct gaacactggt 840 cccctgggcc cccttatttc tttctctata ctttgtctac gtgtcttttt ccaagtctct 900 cattccacct aacgagaaac acccacaggt gtgaaggggc aacccacccc ttca 954 <210> 195 <211> 4487 <212> DNA <213> Homo sapiens <400> 195 gtcaggcctc tgagcccaag ctaagccatc atatccccag tgacctgcac atatacatcc 60 agatggcctg aagcaactga agatccacaa aaaaagtgaa aatagcctta actgatgaca 120 ttccaccatt gtgatttatt tctgccccaa cctaactgat caatgtactt tataatctcc 180 cccaccctta agaagtttct ttgtaattcc ccccaccctt gagaatgtac tttgtgagat 240 ccgcgccctg tccccaaaat attgctctta actccactgc ctatcccaga acccataaga 300 actaatgata atcccaccat cctttgctga ctcctttttt ggactcagtc tgcctgcacc 360 caggtgaaat aaacagcctt gctgctcaca caaagcccgt ttggtcctct cttcacatgg 420 acacgtgaaa catttggtgc cgaagatccg ggtcagtggg actccttcag gagaccagtc 480 ccctgtcttc accctcactc cgtgaagaga tccacctatg acctcaagtc ctcagaccaa 540 ccagcccaag gaacatctcg ccgattttaa atcgggtaag tggcctcttt ttactctctt 600 ctccaacctc tctcactatc cctcaacctc tttctccttt caatcttggt gccatgcttc 660 aatctctccc ttctcttaat ttcaattcct ttcattttct ggtagagaca aaggagacac 720 attttatctg tggaaccaaa actccggcgc tggtcacgga ctcgggaagg cagccttccc 780 ctggtgttta atcattgcgg ggacgcctct ctgattattc acccacattc cattggtgtc 840 tgatctccgc agggacacct gccttggtca ttcacccaca ttcccttggt ggcaagtcaa 900 ttgcggggac gcctgctttg gctgctcacc cacgttgcag cccagggctg ctccccaccc 960 gccttctctg tgtctctacc cttctcttta cacttgcctc cttcactatg ggcaaacttc 1020 caccctccat tcctccttct tctcccttag cctgtgttct caagaactta aaacctcttc 1080 aactcttgcc tgacctaaaa tctaagtgtc ttattttctt ctgcaatacc gcttgacccc 1140 aatacaaact caataatggt tctaaatagc cagaaatcgg cacttttgat ttctccattt 1200 tacaagatct agataatttt cgtcaaaaat gggcaaaagg tgtgaggtgc ctgacgtcca 1260 ggcattcttt tacacatcgg tccctcccta gtctctgctc ccaatgagac ttgtcccaaa 1320 tctttcttct ttctctcctg tctgttcctt cagtctccac cccaagatat gagtcctttg 1380 aatccttctt ttctatggac tcatctgacc tctccccttc tccccaggct gctccttgcc 1440 aggccaagcc aggtcccaat tcttcctcag cctctgctcc ccaaccctaa aatccttcaa 1500 tcacctcccc tcctcacacc ggtctggctt ccaattttgt tcccacgact agccctcccc 1560 acctgcccaa caatttcctc ttagagaggt ggctggagct gaaggcatag tcagggtaca 1620 tgtgcctttt tctcgatcag acctttccca aatcagccag cgtttaggct ctttctcatc 1680 agaccccact aaatatatac tggaattccg atatctaaat ctgtcttaca gtttaacctg 1740 gaatgactta aatgtcatcc taacttctac cctctcccca aatgaacggg aaagagtttt 1800 ttctctagcc caatttcaca ctgataactg ccagcttcat gagccagacc tccatgaagg 1860 cattagagca gttccccgag aagatcccaa tggaactatc aggcaaattc cccaggtata 1920 gctaggcgag attacatggt ttcctgccta gttgaagggc ttaaaaaggc agcttacaaa 1980 gctgttaatt aagacaaact taaaggaact actcaaggta aagacgaaaa cccagcccag 2040 ttcatggcct gcttaggagc aacccttaga ctctttacag ccccagatcc tgaaaggtca 2100 gaaggctgtc ttattctcaa tatgcatttt attttattac ccaatctgtt cccaacatta 2160 aataaagctc caaaaattaa attccagccc tcaaacccca caacaggact taattaggtg 2220 tacaataata gagtagaggc agccaagtag caatgtattt ctgagttgca attccttgcc 2280 tccgctgtga gacaaacccc agccacatct ccagcacaca agaactccaa acacctgaac 2340 cgcagctgcc aggggttcct ctagaacctc ctccctcagg agcttgctac aagtgccaga 2400 aatctggcca ctgggccaag gaatgcccgc agcctgggat tcctcctaag ctgtgtccca 2460 tctatgtgag tccccactgg aaactggact gtccaactgg cccgaggctc tgactgactc 2520 cttcccatat cttctcggct tagcagctga agactgacac tgcccgatcg cctcagaagc 2580 ctcctggacc atcgcggatg ctttgggtaa ctcttacagt ggagggtaag tccgtcccct 2640 tcttaagcaa tacggaggct acccactcca cattaccttc ttttcaaggg tgtatttccc 2700 ttgcctccat aactgttgtg ggtattgacg gccaggcttc taaacctctt aaaactcccc 2760 aactctggtg ccaacatgga cattctttta tgcactcttt tttagttatc cccacctgcc 2820 tagagctccc ttattaggtc gagacatttt aactaaatta tctactttcc tgactattcc 2880 tgggctacag ccacacctca ttgctgcttt ttccccagtt caaagcctcc ttcgcatcct 2940 cctctcatat acccccacct taatccacaa gtataggaca cctctacccc ctccttggcg 3000 actgatcatg cacctcttac catcccatta aaacctaatc acccttaccc tgctcaatgc 3060 caatatccca tcccacagca tgctttaaaa ggattaaagc ctgttatcac tcgcctgtta 3120 cagcttgggc ttttaaagcc tgtaaactct ccttacaatt cccctgtttt acctgtccaa 3180 aaactggaca agccttacag gttagttcag gatctggcct taccaaccaa attgtctggc 3240 ctatccaccc cgtgatgcca aagccatata ctctcctatc ctcaatacct ccctccacaa 3300 cccctccata acccattatt ctgttctgga tctcaaacat gctttcttta ctattccttt 3360 gcacccttca tcccagcctc tcttcgcttt cacttggact gaccctgaca cccatcaggc 3420 tcaacaaatt acctaggctg tactgctgca aggcttcacg gacagccccc atgacttcag 3480 ttaagcccaa atttcttcct catctgttac ctatctcagc ataattgttc acgaaaacac 3540 acatgctctg cctgctgatc atgtccagct aattccccaa accccaatcc cttctacaaa 3600 acaactcctc tccttcctac gcatggttag gtacttccgc ctttggatac ctagctttac 3660 catcctgact aaaccattat gtaaactcac aaaaccaaac ccagctgacc ccatagatcc 3720 taaatccctt tgccactcct ttccgttcct taaaaacagc cctagaagct gcccccacac 3780 tagctctccc taactcattc caaacctttt tcattacaca cagccaaagt gcagggctgt 3840 gcaatcggag ttcttacaca aaagccagga ccgcaccctg tagcctttct gtccaaacaa 3900 cttgacctta ctgttttagc ctagccctca tgtctgcatg cggtggctgc tgctgcccta 3960 atacttccag aggccctcaa aatcacaaac tttgctcaac tcactctata cagttctcat 4020 aacttccaaa atctattttc ttcctcacac ctgacacata cactttctgc tccctggctc 4080 cttcagctgt actcactctt tgttgagtct cccacaatta ccattgttcc tggcctggac 4140 ttcaatccgg cctcccacat tattcctgat accacacctg gcccccatga ctgtatctct 4200 ctgatacact tggcattcac ttcatttccc catgtttcct tctttcctgt tcctcaccct 4260 gatcacactt ggtttattga tggcagttcc accaggccta atcgccaaac accagcaaag 4320 gcaggctatg ctatagtatc ttccacatct atcattgagg ctaccgctgt gccccatctc 4380 cactacctct cagcaagccg aactcattac cttaacttgg gccctcactc ttgcaaaggg 4440 actatgcgtt ggtatttata ctgaccccat atcctgcacc accatgc 4487 <210> 196 <211> 443 <212> DNA <213> Homo sapiens <400> 196 agaccaccac ttctcctgct gccctcctct ctcccacttt tgcctagttt ataagacagg 60 cgaaaaggga gaaagcaaaa agttggaaag aaacagaagt aagataaata gccagacgac 120 cctggcacca ccacctggcc ctggtggtta aaaaaataat aataatatta acccctgacc 180 taaactactt gtgttatctg taaattccag acatcgtatg aggaagccct gcgaaacttt 240 ctgtcctgtc agctgatgca tgtagccccc agtcacgctc cccacgcttg ctcgatctat 300 cacgaccctt tcacgtggac cccttagagt tgtaagccct taaaagggcc aaggatttct 360 ttttcaggga gcttggctct taagatgcaa gtctgccaaa gctcccgccc gaataaagcc 420 tcttccttct ttaatgagga gtt 443 <210> 197 <211> 5995 <212> DNA <213> Homo sapiens <400> 197 ataataatat tgttaaaatg gtctgttcct aacttaactg atgatattat cttgtggaat 60 tccttctcct ggctcatcct ggctcaaaaa ctcccctact gagcaccttg tgaccctcat 120 tcctgcccgc cagagaacaa cccccctttt ttcctttacc tacccaaatc ctataaaacg 180 gcccacccct atctcccttc gctggctctc ttttcggact cagcccacct gcacccaggt 240 gaaataaaca gccttgttgc tcacacaaag cctgtttggt ggtctcttca cacagacaca 300 catgaaattt ggtgccatga ctcggatcgg gggacctccc ttgggatatc aatcccctgt 360 ccccccttga gaaagatcca cctatgacct tgggtcctca gaccgaccag cccaaggaac 420 atctcaccaa tttcaaatac agtaagcggc ctgtttttac tttcttctcc aacctctctc 480 acgatccctc aacctctttc tcctttcaat cttggtgcca cacttcaatc tcccttctct 540 taatttcaat tcctttcatt ttctggtaga gacaaaggag acacatttta tccgtggacc 600 caaaactcca gcaccggtca cggactcagg aaggcagcct tcccttggtg tttaatcatt 660 gcaaggacag ctctctgatt attcacccac gttccactgg tgtctgatct ctgcggggac 720 acctgccttg atcattcacc cacattccct tggtggcgag tcaattgcgg ggacacctgc 780 cttgatcatt cacccacatt cccttggtgg caagtcaatt gcggggacgc ctgccttgat 840 cattcaccca cattcccttg gtggcgagtc aattgcgggg acgcctgctt tggctgctcg 900 cccacattgc agcccagggc tgttccccac ccccttctcc gtgtctctac ccttctcttt 960 aaacttgcct ccttcactat aggcaacctt ccaccctcca ttcctccttc ttctccctta 1020 gcctgtgttc ttaagaactt aaaacctctt caactctcgc ctgacctaaa atctaagcat 1080 cttattttct tctgcaacac cgcttggccc caatagaaac ttgacaatgg ctccaaatag 1140 ccagaaaaca gcacttttga tttttccatc ctacaagatc gagatgattc ttgtcataaa 1200 atgggcaaat ggtctgaggt gcctgacgtc caggcattct tttacacact gttccctccc 1260 ttctctctgt tcccaatgcg actcgtccca aatcctcctt ctttccctcc cgcctgtcct 1320 ctcagtccca accccaagca tcgctgagtc tttctaatct tccttttcta cagacccatc 1380 tgacctctcc cctcttcccc aggctgctcc tcgccaggcc gagccaggtc tcaattcttc 1440 ctcggcctct gctcccacac cctataatcc ttttatcacc tcccctcctc acacccggtc 1500 tggcttacag tttcattctg tgactagccc gccccaacct tcccagcaat ttcctcttaa 1560 aaaggtggct ggagctaaag gcacagtcaa ggttaatgct cctttttctt tatccgacct 1620 ctctcaaatc agttagcatt caggcttttt catcaaatat gaaaaatcca gcccagttca 1680 tggctcgttc ggcagcaacc ctgagacgct ttacagccct agaccctaaa aggtcaaaag 1740 gccgtcttat tctcaatata cattttatta cccaatccgc tcctgacatt aaataaaact 1800 ccaaaaatta aattccagcc ctcaaacccc acaacaggac ttaattaacc tcgcctttaa 1860 ggtgtacaat aataaagtag aggcagccaa gtagcaacat atttctgagt tgcaattcct 1920 tgcctccact gtgagacaaa ccccagccac atctccagca cacaagaact tccaaacacc 1980 taaaccgcag tggccagagt ttccttcaga acctcctccc ccaggagctt gctacaagtg 2040 ccggaaatct ggccactagg ccaaggaatg cccacagccc gggattcctc ctaagccgtg 2100 tcccatctgt gcaggaccca actgaaaatc ggactgttca actcacctgg cagccactct 2160 cagggcccct agaactctgg cccaaggctc tctgactcct tcccagatct tctcagctta 2220 gcagctgaag actgacactg ccagatcgcc tcaaaagcct acaggaccat cacagacgct 2280 ctgggtaact ctcacagtgg agggtaagtc tgtccccttc ttaatcaata cagaggcaac 2340 ccactccaca ttaccttctt ttcaaaggct tgtttccctt gcctccgtaa ctattgcagg 2400 tactgacggc caggcttcta aacctcttaa aactcctcaa ctctggtgcc aacttagaca 2460 atactctttt aagcactcct ttttagttat ccccacctgc cctgttccct tattaggccg 2520 agacacttta actaaattta aattatctgc ttccctgact attcctgggc tacagccaca 2580 cctcattgct gccttttccc ccagttcaaa gcctccttca catcctcccc ttgtatctcc 2640 ccaccttagc ccacaagtat aggacacctc tactccctcc ttggcgaccg atcatgcacc 2700 ccttaccatc ccattaaaac ctaatcaccc ttatcccgct caatgccaat atcccatccc 2760 ttagcacgct ttaaaaggat taaagtctta tcaatcgcct gctacagcat ggccttttaa 2820 agcctataaa ctccccttac aattccccca ttttacctgt cctaaaacca ggcaaggctt 2880 acaggttagt tcaggatctg cgtcttatca accaaattgt tttgcctatc caccccgtgg 2940 tgccaaaccc atatactctc ctatgctcaa tacctccctc cacaacccat tattctgttc 3000 tggatctcaa acatgctttc tttactattc ctttgcaccc ttcatcccag cctctcttca 3060 ctttcacttg gactgaccct gacacccatc aggctcagca aatcacctgt gctgtactgc 3120 cgcaaagctt cacagatagc ccccattact tcagtcaagc ccaaatttct tcctcatctg 3180 ttacctatct cggcataatt ctcataaaaa cacacgtgct ctccctgccg atcgtgtccg 3240 actgatctct taaaccccag caccttctac aaaacaactc ctttccttcc taggcatggt 3300 tggatacttt tgactttaga tacctggttt tgccatccta acaaaaccat tatgtaaact 3360 cacaaaagga aacctagctg accccataga tcctaaatcc tttccccact cctttctgtt 3420 ccctgaagac aactttagag actgccccta ccctagatct ccctgaatga tcccaaccct 3480 tttcattacc cacagctgga gtgcagggct gtgcagtcag aattcttaca caagaaccgg 3540 gaccgcgccc tgtagccttt ttatccaaac aatttgacct tactgttttg cctagccctc 3600 aagtctgcgt gctgcggccg ccaccgccct aatactttta gaggccctta aaatcacaaa 3660 ctatgctcaa ctcactctct acagttctca taacttccaa aatctatttt cttcctccca 3720 cctgacacat atactttctg ctccccggct ccttcagctg tactcactct ttgttgagtc 3780 tcccacaatt accattgttc ctggcccaga tttaatccgg cctcccacat tattcctgat 3840 accacacctg acccccatga ctgtatctct ctgatccacc tgacattcac cccatttccc 3900 catatttcct tctttcctgt tcctcaccct gatcacactt ggtttattga tggcagttcc 3960 atcaggccta atcgccacac accagcaaag gcaggctgtg ctatagtaca agccactagc 4020 ctgcctctta gaacctctca tttcctttcc atcgtggaaa tctatcctca aggaaatcac 4080 ttctcagtgt tccgtctgct attctacaac ttctcaggga ttattcaggc cccctccctt 4140 ccctacacat caagcttaga gatttgcccc cacccaggac tggcaaattg actttgctca 4200 acatgccctg agtcaggaaa ctaaaatacc tcttggtcta ggtagacact ttcactggat 4260 aggtagaggc ctttcccaca gggtctaaga agaccaccac ggtcatttct tcccttctgt 4320 cagatataat tccttggttt ggccttccca cctctataca gtccgatagc agactggcct 4380 ttattagtca aatcagccaa gcattttttt tcaggctctt ggtattcagt gaaaccttta 4440 taatccttac agtcctcagt cttcaggaaa ggtagaatgg actaatggtc ttttaaaaac 4500 acacctcagg ccgggcgcgg tggctcacgc ctgtaatccc agcactttgg gaggccgagg 4560 cgggcggatc acgaggtcag gagatcgaga ccatcccggc taaaacggtg aaaccccgtc 4620 tctactaaaa atacaaaaaa ttagccgggc gtagtggcgg gcgcctgtag tcccagctac 4680 ttgggaggct gaggcaggag aatggcatga acccgggagg cggagcttgc agtgagccga 4740 gatcccgcca ctgcactcca gcctgggcga cagagcgaga ctccgtctca aaaaaaaaaa 4800 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa cacacctcac caagctcagc caccaactta 4860 aaaaggactg gacaatactt ttaccacttt cccctctcag aattcaggcc tgtcctcaga 4920 atgctacaag gtacagccca tttaagttcc tgtatagacg ctccttttta ttaggcccca 4980 gtctcattcc agacaccaga ccaacttgga ctgtgcccca aaaaacttgt catccctact 5040 atctcctgtc tagtcatact cctattcacc gttctcaact actcatacat gccctgctct 5100 tgtttacact gtttctccaa gccatcacag ctgatatctc ctggtgctat ccccaaactg 5160 ccagtcttaa ctcttaaagt aaataaataa tctttgctgg caggactatg ctgaatctcc 5220 ttaggcactc tctaattaga tgtcttaggt cctcccaatt cttagacctt taatacttgt 5280 ctttctcctt ctcttattcc atttagcttt tcaattcata caaaaccata tccagaccat 5340 caccaataat tctaaatgac aaatgtttct tctaacaacc ccacaatatc atcccttacc 5400 acaaaatctt ccttcagctt aatctctccc gctttaggtt cctacacctc ccctaatccc 5460 gctcaaagca gccctgagaa acatcgccca ttgtctctcc ataacacccc caaaaatttt 5520 caccgtccca acattctacc actatttcat tttatttttc ttattaatat atgaagacag 5580 gaatgtcagg cctctgagcc caagctaagc catcatatcc catgacctgc acgtacacat 5640 ccagatggcc ggttcctgcc ttaactgatg acattccacc acaaaagaag tgaaaatggc 5700 ctgttcctgc cttaactgat gacattatct tgtgaaattc cttctcctgg ctcatcctgg 5760 ctcaaaagct cccctactga gcaccttgtg acccccactc ctgcccgcca gagaacaacc 5820 cccctttttt cctttaccta cccaaatcct ttaaaacggc cccaccccta tctcccttcg 5880 ctggctgact ctcttttcag actcagccca cctgcaccca ggtgaaataa acagccctgt 5940 tgctcacaca aagcctgttt ggtatggtgg tctcttcaca cggacgcaca tgaaa 5995 <210> 198 <211> 831 <212> DNA <213> Homo sapiens <400> 198 ttacagtagg tagctagtca gacatgagca gggcaggaga gggctccacc accaccagga 60 atgtcaggcg accatcagct gatggtcagg cagttgtcaa ccgtctctct aaaatgataa 120 ttggatgcag ccagcgccag ggaaagggag ggtcccagta gatagaaaga acctggaact 180 gacgaccagc agcttcctgg taagatttca ggagttgggc acgtgggctc aagcatgtgc 240 actaggaggc aaaacggtgg cactaggagg catgtgcact aggaggcaaa accctcctct 300 aggaaggctg gactggtaag ggaagaaacc aggaaataaa tcacagaaac aaaccatctg 360 gtaaagaaaa cacaaagagg aatgaagatt aagggaggga gagagggagg gaggggaaat 420 gctctttaat gagggtctct ctcgcaacag aaacttccac tgttacttca tttgagttct 480 ccagggagcg cgtgcacaac ctcggtaaac acactgcgct ccctcccaag ggcttgcagg 540 ccaccctcag ggaagaaccg ggggaggagt aacgcaaacc ccagaaccac gccaatgtac 600 aaaaccccaa gtcaaaagtc acacagcacg tttgatctcc aagtcaccca ctggccctct 660 cccaagtgta ctttatttcc tttcattccg gtctaaagct ttttaataaa ctttctctcc 720 tgctctaaaa cttgccttgg tctctcactc tgcctgaggc ccctcaaatt ctttcttctg 780 aagaggcagg aagtgagggt gctacggacc catatggatt cactgctgcg a 831 <210> 199 <211> 430 <212> DNA <213> Homo sapiens <400> 199 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac gtatacatcc 60 agatggcctg aagtaactga agaatcacag aagaagtgaa aatggcccat tcctgcctta 120 acttatgaca tcccaccatt gtgatttgtt gctgccccac cttaactgag cgattaacct 180 tgtgaaattc cttctcctgg cttagaaact cccccactga gcaccttgtg acccccacct 240 atgcctgcaa gagaaaaacc ccttttgact gtaattttcc actacccaca caaatcctat 300 aaaacggccc cacccctatc tcccttcgct gactctttct ggactcagcc cgcctgcacc 360 cagttgaaat aaacagcctt gttgctcaca caaagcctgt ttggtggtct cttcacacgg 420 atgcgcgtga 430 <210> 200 <211> 4482 <212> DNA <213> Homo sapiens <400> 200 tcacaaaaga agtgaaaatg gccaattcct gccctaactg atgacattac cttgtgaaat 60 tccttctccc ggctcagacg ctcccccact gagcacctca tgacccccgc ccctgcttgc 120 cggagaacaa cccctttgac tgtaattttc cactacctac ccaactccta taaaatggcc 180 ccacccctat gtccctttgc tgactctttt tggactcagc ctgcctgcac ccaggtgatt 240 aaaaagcttt attgctcaca caaagcctct ttggtggtct cttcacacgg acgcgcgtga 300 catttggtgt cgaaacattt ggtgccgtga ctcggattgg gggacctccc ttgggagatc 360 aatcccctgt cctcctgctc tttgctccgt gagaaagatc catctacgac ctctggtcct 420 cagaccaacc agcccaagga acatctcacc aattttaaat tgggtaagcg gcgtcttttt 480 actgtcttct ctgtcctctc actatccctc aacccctttc tcctttcaat ttctgcgcca 540 cctttcaatc tctcccttcc cttaatttca gttcctttct ttttctggta gagacagagg 600 agacgcgttt tatccgtgaa cctaaaactc cggtgccagt cacagacttg ggaagacagt 660 ctttcctttg tgtttaatca cgcggggaca cctgcctgat tattcagcca catttcagag 720 gtgtctgatc accatgggga cgcctgcctt gatccttcac cttggtggca agcactacct 780 ccccgaggcg gggcaagtac cctcccaccc cttctctcca tgtctctacc ctctcttttc 840 tctgggcttg cttccttcac tatgggcaac cttccaccct ccattcctcc ttcttctccc 900 ttagcctgtg ttctcaaaaa cttaaaacct cttcaactca cacctgacct aaaacctaaa 960 tgccttattt tcttctgcaa caccgcttga ccccaataca aacttgacag tgtttccaaa 1020 tagccagaaa atgtcacttt tgatttctcc atcctacaag atctagataa ttcttctcgt 1080 aaaatgggca aatggtctga ggtgcctgac gtctaggcat tctttttcac atcagtccct 1140 ttctaatctc tgctcccaat gcaactcgtc ccaaatcttt cttctttctc tcctgtctgt 1200 tccttcagtc tccaccccaa gctctgagtc ctttgaatcc tccttttcta cagacctata 1260 tgacctctct cttcctcccc aggctgcccc ttgccaggcc gagccaggtc ccacttcttc 1320 ctcggcttct gctcctccac cctataatcc ttctatcacc tcctctcctc acacccagtc 1380 cggcttacag tttccttctg tgactagccc ttccccacct gcccaacaat ttcctcttaa 1440 agaggtgtct ggagctaaag gcatggtcaa ggttattgct cctttttctt tatccagcct 1500 ctcccaaatc agttagtgtt taggcttttt ttcatcaaat atgaaaaccc agcccagtcc 1560 gtggcttgtt tggcaacaac ccttagagac tttaccttcc tagacccaga aaggccagaa 1620 ggccgtctta ttctcaatat gcattttatt acccaatctg ctcctgacgt ttaaaaaaag 1680 ctccaaaact taaattccag ccctcaaacc ccacaacagg atttaattaa ccttgccttc 1740 aaggtgtaca ataattaaaa agaggcagcc aagcagcaat gtatttctga gttgcaatta 1800 cttgcctctg ctgtgagaga aaccccagcc acatcttcag cacagaagaa cttcaaaacg 1860 cctaagccac agtggtcagg cattccttca ggacctcctc ccccaggatc ttgcttcaag 1920 tgctggaaat ctggccactg ggccaaggaa tgcctgcagc ccgggattcc tccttagtca 1980 tgtcccatct gtgcgggacc ccactggaaa tcgaactgtc caacttgccc ggcagccact 2040 cccagagccc ctggaattct ggcccaaggc tctctgactc cttccccgat cttctcggct 2100 tagcagctga agactgacac tgcctgattg cctcaaaagc ctcctggacc atcacaggcg 2160 cttgaggtaa ctcttacagt ggagggtaag gccgtcccct tcttaatcaa tacagagact 2220 acccactcca cattaccttc ttttcaagga ccgtttccct tgcctccata actgttgtag 2280 gtattgatgg ccaggcttct aaacctctta aaactcccca actctggtgc caacttagac 2340 aatattcttt tttttttttt tttttttttt tggagatgga gtctcactct gtcaccgagg 2400 ctggagtgca gtggcgtgat ctcggctcaa taatacaagc tccgtctcct gggttcacac 2460 cattctccca cctcaacctc ctgaatagct gggatgacag gcgtccgcca ccatgcccag 2520 ctaatttttt gtatttttaa tagtgacggg gtttcaccat gttagccagg atggtctcga 2580 tctcctgacc tcgtgatctg cccgccttgg cctcccaaag tgctgggatt acaggcgtga 2640 gccatcgcgc ccggccgctt agacaatatt cttttgtgca ctccttttta gttatcccca 2700 cgtgcccagt tcccttatta ggtctaggca ttttaactaa cttatctgct ttcctgacta 2760 ttcctaggct acagccacaa ctcattgccg cccttttccc cagttcaaag cctccttcac 2820 atcctcccct tgtgtctccc catcttaatc cacaagtatg agacacctct attcctacct 2880 tggcgaatga tcatgcaccc cttaacatcc cattaaaacc taatcaccct taccccactc 2940 aatgccaata tcccatccca ccgcatgctt taaaaggtta aagcctgtta tcactcactt 3000 gctacagcat gggcttctaa agcatataaa ctctccttac aattctccca ttttacccat 3060 ccaaaaacca gacaagtctt acaggttggt tcaggatcta tgccttatca accaaattgt 3120 tttgcctgtc caccctgtag tgcccaaccc gtacactctt gtcctcaata cctccctcca 3180 caacccattt ttctgttctg gatctcaagc atgcttcctt tactattcct ttgcaccctt 3240 catcccagcc tctctttgct ttcacttgga ctgaccctga cacccatcag tctcagcaac 3300 ttacctaggc tatactgcca caaggcttca ggaacagccc ccattacttc agtcaagccg 3360 tttctcatga tttactttct ttccatccat ctgcttctca ctttattcaa tattttgaca 3420 accttctact ttatagcccc tcctacaaat cttcccaaaa ggacaccctt ctgctcctcc 3480 aacatctgtt ctcaaaagaa tatcgcgtat cctccttcaa agcccaaatt tcttcctcat 3540 ctgttaccta tctcggcata attcttaata aaaacacacg ttctctccct gctgatcgtg 3600 tctggctaat ctcccaaacc ctaacccctt ctacaaagca acaactcctt tccttcctag 3660 catggttagg tactttcacc tttggatacc tggttttgcc atcctgacta aaccgttata 3720 taaactcaca aaaagaaact tagctgacct catagatcct aaatcctttc cccactcctc 3780 tttcctttcc ttaaaaacag ccctagaagc tgcttccaca ctagctctcc ctaactaatc 3840 ccaacccttt tcattacaca cagccgaagt gcagggctgt gcggtcagaa ttcttacacg 3900 agagccggga ccgtgccctg tagcctttct gtccaaacaa cttgacctta ctgttttagg 3960 ctggccccca cattattcct gataccacac ctgaccccca tgaccgtgtc tctctgatcc 4020 acctggcatt cactccattt ccccatattt cattttttcc tgttccccac cctgatcaca 4080 gtttgttttt gtttttgttt ttttgagatg gagtcttgct ttgtcgccca ggctggagtg 4140 cagtggcatg atctcggctc actgcaagct ccgcctcccg ggttcatgcc attccctggc 4200 ctcagcctcc caagtagctg ggactacagg cacctgccat catgcccggc taattttttt 4260 tttttgtatt tttagtagag acggggtttc accgtgttag ccaggaaggt ccctaactcc 4320 tgaccttgtg atccgcccgc ctcggcctcc caaagtgctg ggattacagg cgtgagccac 4380 cgtgcctggc ccacagttgg tttattaatg gcagttccac caggcttaat cgccactcac 4440 cagctaaggc aggctatgct atagtatctt ccacatctgt ca 4482 <210> 201 <211> 4627 <212> DNA <213> Homo sapiens <400> 201 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac atccagacgg 60 cctgaagtaa ctgaagaatc acaaaagaag tgaaaatagc ctgttcctgc cttagctgat 120 gacgttccac cacaaaagaa gtgaaaatgg cctgttcctg ccttaactga ttatattatc 180 ttgtgaaatt ccttctcctg gctcgtcctg gctcaaaagc tcccccactg agcaccttgt 240 gacccccatc cctgcccacc agagaacaac ccccctttga ctaattttcc tttacctgcc 300 caaatcctat aaaacagccc catccctatc tcccttcgct gactctcttt tcggactcag 360 cccacctgca cccaggtgaa ataaacagcc ttgttgctca cacaaagcct gtttggtggt 420 cccttcacat ggacgtgagt gaaatttggt gccctgactc ggatcagcgg acctcccttg 480 ggagatcaat cccctgtcct cctgctcttt gctccgtgag aaagatccac ctacgacctc 540 tggtcctcag actaaccagc ccaaggaaca tctcaccaat tttaaatcag gtaagcggcc 600 tctttttact ctcttctcca acctctctca ttatccctca acctctttct cctttcaatc 660 ttggtgccac acttcaattt ctcccttctc ttaatttcag ttcctttcct tttctggtag 720 agacaaagga gacacgtttt atccatggac ccaaaactcc ggcaccagtc acagactcgg 780 gaaggcagtc ttcccttggt gtttaatcat tgcagggaca cctgcctgat tattcaccca 840 catttaattg gtgtctgatc actgcaggga tgcctgcctt ggtcattcac ccacattccc 900 ttggtggcaa gtcaattgcg gggacgcctg ctttggctgc tcactcacat tgcagcccag 960 ggctgctcac cccacccctt ctctccgtgt ctctacccct tctccacttt cctggggggc 1020 aagcaccccc caccccttct ctctgtgtct ctccccaccc cttctccact ttcctgggag 1080 gcaagcaccc cccacccctt ctctccatgt ctctaccctt ctctttaaac ttgcctcctt 1140 cgctatgggc aaccttccac cctccattcc tccttcttct cccttagcct gtgttctcaa 1200 gaacttaaaa cctcttcaac tctcacctga cctaaaatct aagcatctta ttttctactg 1260 taatgtcact tgggcctgat acaaactcga gagtagttcc aatagtcaga gaatggcact 1320 ttcaattttt ccatcctata agatctagat aattcttgtc ataaaatggg caaacggtct 1380 gagatgcctg acgtccaggc atttttttac acatcagtcc ctccctagtc tctgttccca 1440 atgcagcttg tcccaaatcc ttcttttcct cccgactgtc ccctcagtcc caaccccaag 1500 cgtcgctgag actttctgat cttccttttc tacagaccca tctgacctct cccctcctcc 1560 ccaggctgct cctcaccagg ccaagccagg tcctaatttt tcctcggcct ccgctccccc 1620 accctataat ccttttagca cctcccctcc tcacgcctgg tccggcttag tttccttccg 1680 caactagctc tcccccacct gcccagcaat ttcctcttaa aaaggtggct ggagctggcc 1740 aggtgcagtg agtcagacct gtaatcccag cactttggga ggctgaggca ggcagataac 1800 aaggtcagga gattgagacc atgctgacta acacggtgaa accccatctc tactaaaaat 1860 acaaaaactt agccaggcat ggtggcaggt gcctgtagtc ccagctactc gggaggctga 1920 ggcaggagaa tggcgtgaac ctggaaggca gagcttgcag tgagccgaga tcgtgtcact 1980 gcactccagc ctgggcggca gagcaagact ccatctcaaa aaaaaaaaaa aaaaaagggg 2040 gctgccagct aaaggcatag tcaacgttaa tgctctcttt tctttatccg acctctccca 2100 aatcagatag cgtttaggct ctttttcatc aaatataaaa acccagccca gtccatggcc 2160 catttggcaa caacccttag atgttttact gccctagacc cagaagggcc agaaggccat 2220 cttattctca acacgcattt tattacccaa cccactcccg acagtagaaa aagctccaaa 2280 aattagattc cagtcctcaa accccacaac aggacttaat taacctcgcc ttcaaggtgt 2340 acaataataa agtagaggca gccaagtagc aatgtatttc tgagttgcaa ttccttgcct 2400 ccactgtgag acaaacccca gccacatctc cagcacacaa gaacaccaaa cacctgaacc 2460 acagctgcca ggggttcctc caaaccctct taccccagga gcttgctaca agtgccagaa 2520 atctggccac tgggccaagg aatgcctgca gcccaggacc cctcctaagc tgtgtcccat 2580 ctgtgtggaa ccccactgaa aataggactg ttcagctcgc ctggcagcca ctcccagagc 2640 ccctggaact ctggcccaag gctctctgac tgactccttc ccagatcttc tcagcttagt 2700 ggctgaagac tgatactgcc cgatcacctc agaagcctac aggaccatca cagacgcttt 2760 gggtaacttt tacagtggag ggtaagtctg tccccttctt aatcaatact gaggctacca 2820 actccacatt accttctttt caaggactgt ttcccttgcc cccataattg ttgtgggtat 2880 tgacggccag gcttctaaac ctcttaaaac tccccaactc tggtgccaac ttggacaata 2940 ttcttttata cattcctttt tatttaaccc cacctgccca gttcccttat taggccgaga 3000 cattttaacc aaattatctg cttcccttat tattcctgga ctacagccac atctcattgc 3060 cacccttctt cccaacccaa agcctccttc gtgtcttcct ctcgtatccc cccaccttaa 3120 cccacaagta taggacacct ctactccctc cttggcaatg gatgatgcac cccttaccat 3180 cccattaaaa cctaatcacc cttaccccac tcaacgccag tatcccatcc cacagcatgc 3240 tttaaaagga ttaaagcctg ttatcactcc cctgttacag catggccttt taaagcctat 3300 aaactctcct tacaattccc cattttacct gtccaaaaac cggacaagcc ttacaggttt 3360 agttcaggat ctgcacctta tcaaccaaat tgttttacct atccacctca tggtgacaaa 3420 cccatatact ctcctatcct caatacctcc ctccacagcc cattcttctg ttctggatct 3480 caaacatgct ttctttacta ttcctttgca cccttcatcc cagcctctct tcgctttcac 3540 ttggactgac cctgacaccc atcaggctca gcaaattacc tgggctgtac tgctacaagg 3600 cttcacagac agcccccatt acttcagtca agcccaaatt tcttcctcat ctgttaccta 3660 tctcagcata attctcataa aaacacatgt gctctccctg ctgatcgtgt ctgactaatc 3720 tcccaaaccc caatcccctc tacagaacaa caactccttt cctttcctag gcatggttag 3780 tgtggtcaga attcttaccc aagagtcggg accgcgccct gtagcctttc tgtccaactt 3840 gaccttactg gtttagccta gccttcatgt ctgcatgcag cagctgccgc tgctttaatg 3900 cttttagagg ccctcaaaat cacaaactat gctcaactca ctctctacag ttcccataac 3960 ttccaaaatc tattttcttc ctcccacctg gggcatatac cttctgctcc ctggcttctt 4020 cagctatact cactctttgt tgagtcttcc acaattacca ttgttcctgg cctggacttc 4080 aatccagcct cccacattat tcctgatacc acacctgacc cccgtgactg tatctctctg 4140 atccacctga cattcactcc atttccccat attctttcct cttcctcacc ctgatcacac 4200 ttggtttatt gacggcagtt ccaccaggcc taattgccac tcaccagcaa aggcaggcta 4260 tgctatagta tcttccacat gtatgattga ggctaccgct ctgccccctt ccactacctc 4320 tcagcaagct gaactcattg ccttaacttg ggccctcact cttgcaaagg gactacatgt 4380 caatatttat actaactcta aatatgcctt ccatatcctg caccaccatg ctgttatatg 4440 ggctgaaagg ggtttcctca ctactcaagg gtcctccatc attaatccct ctttaataaa 4500 aatgcttctc aaagctgctt tacttccaaa ggaagctgga gtcattcact gcaaaggcca 4560 tcaaaaggca tcagatccat ggctcaggac aaagcttctg ctgataaagt agctaaaaaa 4620 gcagcta 4627 <210> 202 <211> 376 <212> DNA <213> Homo sapiens <400> 202 gtcaggcctc tgagcccaag ctcatatccc ctgtgacctg cacctataca tccagatgac 60 ctgaagtaac tgaagaatca caaaagaagt gaaaatggcc agttcctgcc ttaactgatg 120 acattacctt gtgaaattcc ttctcctggc tcatcctggc tcaaaaagct cccccactga 180 gcaccccact cctgcccgcc agagaacaac ccctctttga ctgtaatttt cctttaccta 240 cccaaatcct ataaaacagc cccacctcta tctccctttg ctgactctct tttcggactc 300 agcccacctg cacccaggtg aaataaacag ccttgttgct cacacaaagc ctgtttggtg 360 gtctcttcat agggac 376 <210> 203 <211> 4831 <212> DNA <213> Homo sapiens <400> 203 gtaggagatt ggtcagggtg gtggaaaaaa ttgtagaaag acacaaacct tcttggacgt 60 ccaggaggtt ttataaaagc tttggaaaag catttggctg aaggcagcca aaccctctta 120 tccggagccc gagagcgaag gttacataac aaggggatat aaaggaattg atctagataa 180 gttagtttat ttaggccttg gaacctggcc tttaatcatc cacgtgcagg actgctctct 240 ccagggaggg tgaccatgtt aattacccac aagtgtgttg actcaaagcc tttgtcatta 300 aatctgtact aaataaatgc cagcagcacc agcttgtcag ggctgcggct gctacaactc 360 tttctgtcag cggtctggtc ccttagccta ctctttcact caatacttgt gtctaagtac 420 attctttcat ccatcattca gccagggtct atgggtcaga cccagcaggt ggtgctccac 480 atgaggaatg ctgcaatgga ctgcgataga accctcaaaa atgaaggtga aaagactgcg 540 cagtcagtaa gtcagtaagt cattggtgcc cactcaggat ttccaagttg gagagaactg 600 ttcaggctag ggtttcatca taggacaaca gttatcagct caacagcaac agtatataaa 660 agcattgaaa cagctgctta aaggtagcag agccttggtt tcgcaggctc aattaagaga 720 cctaatgcaa actactgttt cccataaccc atggtttctg aaagaaggtg cactaaactt 780 ggagatctgg gaacaagtgg gtagaaatct taaacaacat gatgtacaag ggcaatgggt 840 cccaataaca tctttaacgt tatgggcttt agttagggtg gctctggtcc tactctacac 900 agaagagcct aaaaagggaa gggaggaaga actgtcacct accttactgc ctccatctcc 960 ctcagccccg ctgtctccag gaaaaaataa caaagaggaa atggaggttt tgcctgaggc 1020 ccctcatcca aaaaattgga aaaaagacaa gggatatgct gtcttacgca agcagcatta 1080 gatggggagc tcttagcctg cctggtaatg caagatcaac aaggcaatca tttcttttaa 1140 tgcttataaa gagctaaaaa aaaaaaagca ttaaagaaaa cggagccact agcccattta 1200 caagagggtt aactgaggcc actctgcaga cctctttcta acaatggcca ctgttatttc 1260 tcccctaccc ctaacgtggc tctctcaaaa tcctatttgg gtagaacagt agcctttaaa 1320 gggagagaaa ttataaagag cccatgaatt agccgaggag caattaaaag ctgaccatat 1380 agaaccgtca tacagtcctt gtaatttgcc cattttcatc attccccaaa agtctggtaa 1440 atggagactt ttgcatgact tacgtgctat tgatgctaat ttgcaaccta tggggcccct 1500 tcagcagggg ctcccctccc acgtggcaat tcctcgagac tggcctataa tcattattga 1560 cttaaaaggc tgctcttata ctattcccct tgcagaacgg gacagagaaa aatttgcatt 1620 tacaatacca gctatcaata atgaaaggcc agctcactga tttcattgga aagtgcttcc 1680 tcaaggaatg ctgaacagtc ctaccatgtg tcagtatcat gtaaatcaag cttggctccc 1740 cagtagaaaa gaatttccta attgcaggat tactcatttt acagatgata ttttactagc 1800 agccccaaca gagctagtac ttttcaagtc acatgcctct gtcgtaaaga atacacagtt 1860 aagaggttta atcatagaac ctggaaaagt acagatgtct ttctccttgg aaatatcttg 1920 ggtacatact aatttcccag tcagtaagac ctcaaaaggt taaattaaat actagcaact 1980 tacatacctt aaatgatgat cagaaattac taggtaatat taactggatt tgccccacct 2040 tggacataac tactgataag ttacagaact tgttttccat cttaaaaggc aatgctgccc 2100 tagactctcc taggtattta actcctgcag cacaaaggga aattgaagag atagagcaag 2160 ctatttctca gagacaacta gattgcattg atacatggta ttcagttcaa ttatttgttt 2220 ttcccactaa acactcccct acagatgacc ccagggctac gcttcctaga atgggttttt 2280 tgctcacata ccgggactaa aacactcttt ccctatatcc agttagtcag taaagtcatt 2340 tattcaggat gcagatgatg caatcagttg ctaggttatg accctgatat catcaggatt 2400 cctttaagta aaaagcaatt caaggcagta ttgccttatc tatggacctg caaatagcac 2460 tctctgatta caaaggccat atagagcatg cccttcctgc tgacaaactc cttcagttct 2520 tatcttgtac ttctgtggtt ttgcctacta aaacagttca atcccccata tctaatgctt 2580 taacagtgtt tactgatggc tctggtaaac atggaaaagt cactttctgg tggaaatcac 2640 gtaattccct cacttgttct ggatttacta gcgctcagag ggctgagatt ggagccttac 2700 tattggcctt ggaaactttt tccattcagc tcatcaatat tgttagtgag tctgcttact 2760 ctgtttattt attgcagaac cttgagaggg ccctcattaa gtccactctg gagcccaccc 2820 tgtatgcact ttttctccga cttcagcatt tgctagatca acatacacat cctattttta 2880 tcatacatat ttgagcccac agctcactgc ctggcccact ggcttatgac catgatcaag 2940 cagacgtaca agttagaaca tcactgtttg accaagccac ccagtcacat caatttttcc 3000 accaaaactg gagaaactta tctgaacaat ttcaacttac ccagagacta gctaaacaaa 3060 ttaaccggca atgcccagat tgccagctca caggcacgtt ccctccttat acaggtgtta 3120 accctagagg actagaacct aatcagttat ggcaaacacc atgttacaca tgtgcctgaa 3180 tttgaaaaac taagatatgt acatgtatcc attaataaca attctcaatt agcgctcatg 3240 cctttcctgg agagtccacc cgatatgtca ttaaacatcg tcttttaact tttgcattta 3300 tggggtggcc tacaaaaatt aaaactaata atggtctggc ttatgccagc tcacaatttc 3360 aacaattttg tcacagtgga atatccaaca ttccacaggc atcccttata acctccaagg 3420 agaggccata gtagaacata ctcactctat ccttaaaaat atgctcagaa aacaaaaaag 3480 ggggaatatg agtaaggacc ctgcaacact actagcacaa gccttattta cccttaattt 3540 tgaaaattta gatgataaat ttcaattagc tgtagaaaag cactttgcta aaacctctca 3600 agacataaaa cctgcagttt tatggaaaga tgtaaacagt aatgtacggt gtggtccaaa 3660 tgaattgtta acatgtggga gaggatatgc ttgtgttcac accccctcag gtcctctttg 3720 gattccagca cgatccatca aaccttacca tagcatggct aggacccaac ctggtaccag 3780 aaataaagaa aatgacccta taggacctac agccccagaa aatgtggctt cctcggacga 3840 cataggccct ggacaggacg ctgaagaaga gaagtcagaa gactgagcga atctgctctg 3900 gacacagaca ccattcactc cagataattt gttccttcct atgctttatt aaccttttta 3960 attctttcac tttacctgca accctcacct gctactctct attgggccca tctcttagat 4020 acgcctttct tcagccctat tatttaaaca aacaccccct tctcagcttc taacaacacg 4080 actgcttggc taagagggaa tgacatgccc caagtggggt tcctcaataa cggcacacat 4140 tggactaaga tgccaagtaa cactacatgt cactccttaa ttggaaaaga atgtggctaa 4200 ttatactcat atttgtcttc tattatttac taattctagg atgcaaagcc ggaatgcgag 4260 cagtgcccgc cacacctgac aaacctgctg ctgcacacat ctgtactctt caatcaacaa 4320 aacctgatgc taaaaacaga aaagggggag atgtaggaga tcagtcaggg tggtgggaaa 4380 aattgtagaa agatgcaaac cttcttggaa ggcggggagg ttttacaaca gcttcggaaa 4440 tggatttggc tgaaggtagc caaaccctct tatctggacc ttgagagcaa aggttagata 4500 gcaaagagat ataaaggaat tgatctaggt aagttagttt aacttggaac ctggccttta 4560 atcatcccca tgcatgactg ctatctccgg gcagggtgac tatgttaatt acgcaaaagt 4620 gtgttgactc aaagcctttg tcattaaatc tgtaactaaa taaatgcctg cagcaccagc 4680 ttgtcagggc tacagctgct gactctttac agcaccctgc tcggggtcta taagcagcca 4740 ggtcctctag cccgcttttt cactggatac ctgcgtctga ctgcattctt acatccgttg 4800 ttcggccagg gtctgcagat tggacctggc a 4831 <210> 204 <211> 502 <212> DNA <213> Homo sapiens <400> 204 gtaggagatt ggtcactgtg gtgggaaaaa ttgtagaaag atgcaaacct tcttggaagg 60 ccgggagatt ttacaaaagc ttcagaaaag gatttggctg aaggcagcca gattctctca 120 ccctgtgcct gaacgcttag gttagataac aaggagatgt aaagaaactg atctagataa 180 cttagtttac ttagtagaac ctggccttta atcatctgag tgcaggactg ctggggctgt 240 gtgtgtgtgt ggggtgggga aggggggaag caccatgtta attacccaaa agtgtgttga 300 ctcaaggcct ttgtcattaa atctgtataa ataaatgcct gcagcaccag cttgtcaggg 360 ccacagctgc tacaactctt tacaacaccc tccttggggt acatgagcag ccgagtctcc 420 tagcccactc tcactggata cctgtgtctg agtgcatccg ttcatccatc gcttggtcgg 480 ggtctgtggg tcagacccag ca 502 <210> 205 <211> 755 <212> DNA <213> Homo sapiens <400> 205 gagaaacagg actagctgga tttcctaggc cgactaagaa tccctaagcc tagctgggaa 60 ggccgcatcc acctttaaac acggggcttg caactcagct cacacccaac caatcagaga 120 gctcactaaa atgctaatta ggcaaaaaca ggaggtaaag aaatagccaa tcatctattg 180 cctgacagca cggcgggagg gacaaggatc gggatataaa cccaggcatt cgagcgggca 240 acggcaaccc cctttgggtc ccctcccctt gaatgggagc tctgttttca ctctgtttca 300 ctctattaaa tcttgcaact gcactcttct ggcccgtgtt tgttagggct cgagctgagc 360 ttttgctcgc catccaccac tgctgttttg ccgccgtcgc agacccaccg ctgacttcca 420 ttcttccgga tccggcaggg tgtccgctgt gctcctgatc cagcgaggcg cctattgcca 480 ctcccgattg ggctaaaggc ttgccattgt tcctgcatgg ctaagtgcct gggttcgtcc 540 taattgagct gaacactagt cactgggttc cacggttctc ttccgtgacc cacagcttct 600 aatagagcta taacactcac tgcatggccc aagattccat ttcttggaat ccatgaggcc 660 aagaacccca ggtcagagaa cacgaggctt gccaccatct cggaagcagc ttgccaccat 720 cttggaagct ctgtgagcaa ggaaccctgg taaca 755 <210> 206 <211> 772 <212> DNA <213> Homo sapiens <400> 206 gagagacagg actagctgga tttcctaggc caactaagaa tccctaagcc tagctgggaa 60 ggtgaccgct tccaccttta aacacgtggc ttgcaactta gctcacaccc aaccagtcag 120 gtaggaaaaa gagctcacta aaatgctaat taggctaaac aggaagtaaa gaaatagcca 180 atcatctatc gcctgagaac acagtgggcg ggacaataat cgggggatat aaacccaggc 240 attccagcca gcaactgcta ccctctttgg gtcccctcca tttgtatgcg agctctgttt 300 tcactctatt tcactctatt aaatctccca actgcactct tctggtctgt gtttgttacg 360 gctggagctg agctttcgct cgccgtccac cattgctgtt tgccgccgcc acagacctgc 420 cgctgacttc catccctccg gatccggcag ggtgtctgct gtgctcctga tccagtgagg 480 cgccccttgc cgctcccgat tgggctaacg gcttgagatt gctcctgcac ggctaagtgc 540 ccaggttcgt ccttatcgag ctgaacacta gtcactgggt tccatggttc tcttccgtga 600 cccacggctt ctaatagagc tgtaacactc actgcatggc tcaagattcc attccttgga 660 atccgtgagg ccaagaaccc caggtcagag aacatgaggc ttgccaccat cttggaagtg 720 gcccactgcc atcttgggag ctctgggagc aaggaccccc cggtaacagt tt 772 <210> 207 <211> 115 <212> DNA <213> Homo sapiens <400> 207 tggagtaggt aggtagacag acatgagcag ggcagtagag accccccagc cctccaggaa 60 tgtcaggcga ccatcaggtg atggtcagtt ggttgttaac tgtttctctg aaata 115 <210> 208 <211> 171 <212> DNA <213> Homo sapiens <400> 208 ttacagtagg tagctagtca gatatgagca gggcaggaaa gggccccctg cctcccacta 60 ggaatgtcag gcgaccatca ggtgatggtt ggaggttgtt aaactgcctc tctaaaataa 120 taattggtcg tagccagcgc cagggaaagg cagtctccca acagattaaa a 171 <210> 209 <211> 977 <212> DNA <213> Homo sapiens <400> 209 gtggggaaga gaaagagaga tcagtgtctc tttctatacg gactgtgtct atatagaaag 60 aagtagacat gagagactcc attttgttct gtactaagaa aaattcttct gccttgagat 120 gctgttaatc tgtaacccta ccccaaccct gtgctcgcag aaacatgccc tgtgtcgact 180 caaggtttaa tggatttagg gctatgcagg atgtgctttg ttaaacaaat gcttgaaggc 240 agctagcttg ttaaaagtca tcaccactcc ctaatctcaa gtacccaggg acacaaaaca 300 ctgcggaagg aaggccgcag ggacctctgc ctaggaaagc caggtttctc cccatgtgat 360 agtctgaaat atggcctcat gggaagtgaa agacctgacc gtcccccagc ccgacacccg 420 taaagggtct gtgctgagga ggattagtaa aagaggaagg cctctttgca gttgagataa 480 gaggaaggca tctgtctcct gctcatccct gggcaatgga atgtctcggt gtaaaacccg 540 attgtatatt ccatctactg agataggaga aaaccgcctt agggctggag gtgagacatg 600 ctggcggtaa cactgctctt taatgcaccg agatgtttat gtatgtgcac atcaaagcac 660 agcacctttt ccttaacctt gtttatgaca cagagacatt tgttcacatt ttcctgctgg 720 ccctctcccc actattaccc tattgtcctg ccacatcccc ctctgggaga tggtagagat 780 ggtagagata atgatcaata aatactgagg gaactcggag actggggcca gcgtgggtcc 840 tctgtatgct gagcgccagt cccctgggcc catttttctt tctctatact ttgtctctgt 900 gtctctttct tttctcagtc tctcatccca ccccacgaga aacacccaca gttgtggagg 960 ggcaggccac cccttca 977 <210> 210 <211> 971 <212> DNA <213> Homo sapiens <400> 210 gtggggaaaa gaaaaagaga tcagactatt actgtgtcta tgtagaaaga agtagacata 60 agagactaca ttttgttttg tattaagaaa aattcttctg ccttgagatg ctgttaatct 120 gtaaccctac ccccaaccct gtgctcacag aaacatgtgc tgtgttgact caaggtttaa 180 tgggtttagg gctatgcagg atgtgctttg ttaaagaaat gcttgaaggc agcatgcttg 240 ttaaaagtca ccacctctcc ctaatctcaa gtacccaggg acacaaaaca ctgcggaagg 300 ccaggccgca gggacctctg cctaggaaag ccaggtattg tccaaggttt ctccccatgt 360 gatagtctga aatatggcct cctgggaaga gaaagacctg accgtccccc agcccgacac 420 ccgtaaaggg tctgtgctga ggaggattag taaaagagga aggcctcttt gcagttgaga 480 tgagaggaag gcatctgtct cctgcccatc cctgggcaat ggggtgtctc ggtgtaaaac 540 ccaattgtat gttccatcta ctgagatagg agaaaactgc cttaaggttg gaggtgagac 600 atgctggcag caatacttct ctttaatgca ccagatatgt ttatgtatgt gcacatcaaa 660 gcacagcaca ttttctaacc ttgtttatga cacagagaca tttgttcaca tgttttcctg 720 atgacactct ccccactata ccctattgtc ctgccacatc cccctctctg agatggtaga 780 gataatgatc agtaaatact gagggaactc agagactggt gcccgcgtgg gtcctctgta 840 tgctaagcgc cggtcccctg ggcccagttt tctttctcta tactttgtct ctgtgtctct 900 ttcttttctc agactctcgt cccccccagc gagaaacacc cacaggtgtg gaggggcagg 960 ccaccccttc a 971 <210> 211 <211> 4587 <212> DNA <213> Homo sapiens <400> 211 gtcaggcctc tgagcccaag caaagccagc atatgccctg tgacctgcac gtatacatcc 60 agatgacctg aagcaactga agatccacaa aagaagagaa aatagcctta actgatgaca 120 ttccaccatt gtgatttgtt cctgccccat cctaactgac atgatatagt ctcccctgcc 180 cttaagaagg tgctttgtaa tattctcccc agcccttaag aatgtacttt gtatgcctat 240 cccaaaccta taagaactaa tgataatcct actacccttt gctgacttct tttttggact 300 cagcccgccg gcacccaggt gaaataaaca gccttattgc tcacacaaag cctgcttggt 360 gctctcttca cacagacgcg tgtgacattt ggtgccaaag acccgggaca ggtggactcc 420 tttgggagat cagtcccctg tccttgccct cactccatga ggagacccac ctacaacctc 480 gggtcctcag accaaccagc ccaaggaaca tctcaccatt tcaaatcagg taagcggtct 540 tttcactgtt ctccagtctc tcttgctacc cttcaatctc cctgtccttc caattccagc 600 tctttttcct ctctagtaga gacaaaagag atacatttta tccatggacc caaaactcca 660 gcgtcggtca cggactcggg aagacagtct tcccttggtg tttaatcact gtggcgatgc 720 ctgcctgaat attcacccac actccattga tgtctgatta ccgtggggac gcctgccttg 780 gtcattcacc cacattacct cagtggcagg tcaattgcgg ggacacctgc tttggctgct 840 catccacatt gcagcccagg gctgctcacc gccccccact gccccttctc cgtgtctcta 900 cctttctctt taaactcacc tccttcacta tgggcaacct tccgccctcc attcccccat 960 cttctccctt agcctgtgtt cttaaaaacc taaaacccct tcgactcaca cctgacctaa 1020 aacctaaaca ctttattttc ttctgcaata ctgcttggcc ccagtacaaa ctcgacagta 1080 gttccaagta gccagaaaac ggcacttttg atttctccat tttacaagac ctggatgatt 1140 tttgtcgaaa aatggacaaa tggtctgagg tgcctgacgt ccaggcattc ttttacacat 1200 cagtccctcc ctagtctctg ttcccaatgt gactcatccc aaatctttct tctttctctc 1260 ctgtctgttc cttcagtctc caccccaagt tctgagtcct ttgaatcctt cttttctatg 1320 gactcatctc acctctcccc ttctcgccag gctgctcctc accaggccga gccaggtccc 1380 aattcttcct cagcctctgc tcccccactg tataatcctc ctatcatctc ccctcctcac 1440 acccggtctg gcttacagtt tcgttccacg actagccctc cctcacctgc ccaacagttt 1500 cctcttgaag aggtggctag agctaaaggc atagtcaagg ttaatgctcc ttttttcttt 1560 atccgacctc tcccaaatga gttagcattt aggctctttt tcgtcaaata taaaaaccca 1620 gcccagttca tggcctgttt ggcaacaacc cttagacact ttactgtcct agaccccaga 1680 ggaaggctgt cttattctca atatgcattt tattacccaa tctgctcccg acattagaaa 1740 aagctccaaa aattagattc cagccctcaa accccacaag aagacctaat taacctcccc 1800 ttcaaggtgg tatacaataa tagaatagag gcagccaagt ggcaacgtat ttctgagttg 1860 caattacttg cctccacttt gagagaaacc ccagccacat ctccagcata caagaacttc 1920 aaaacgtctg aaccacagta gccaggtgtt cctccaggac tgcctccccc aggagattgt 1980 ttcaagtgct ggaaatctgg ccactgggcc aaggaatgct cgcagcctgg gattcctcct 2040 aagccatgtg ccaactgtgc aggaccccac tggaaattgg actgtccaac tcgcccggca 2100 gccactccca gagcccctgg aattctggcc taaggctctc tgactgactc cttcccagat 2160 cttcttggct tagcagctga agactgatgc cgcccgatct ccttggaggc cccccggaca 2220 atcactgatg ccgagctttg cgcaactctt acagtggagg gtaaggccgt cctcttctta 2280 attaatatgg aggctaccaa ctccacatta ccttcttttc aagggcctgt ttcccttgcc 2340 tccataactg ttgtgggtat tgacggccag gcttctaaac ctcttaaaac tccccaactc 2400 tggtgccaac ttgaacaaca ttccttaatg cagtcctttt gagttatccc cacttgccca 2460 gctcccttat taggtcgaga cattttaact aaattatctg cttccctgac tattcctggg 2520 ctacagccgt acctcattgc cgcccttttc cccagttcga agtctccttc acatcctcac 2580 cttgtatctc cccaccttaa tccacaagta tgggatacct ctactccctc tttggcaacc 2640 gatcatgtgc cccttaccat cccattaaaa cctaatcacc cttacccagc tcaacgccaa 2700 tatcccatcc cacaacaggc tttaagagga ttaaagcctg atatcacttg cctgctacag 2760 tatggccttt taaagcctat aaattctcct tacaattctc acattttacc tgtccaaaaa 2820 ccggacgagt cttacaggtt agttcaggat ctgaacctta tcaaccaaat tgtcttgcct 2880 atccaccccg tggtgccaaa cccatatact ctcctatcct ccacacctcc ctccacaacc 2940 cattattctg ttctagataa acctagctga ccccataaat cctaaatcct tcccctactc 3000 ccctttccat tccttaaaaa acagccctaa aagctgctct cacactagct ctccctaact 3060 catcccaacc cttttcatta cacacagccg aagtacaggg ctgtgtggtc agaattctta 3120 cacaagaacc gggaccgcgc tctgtagcct ttctgtccaa acaacttgac cttactgttt 3180 tagcctagcc atgtctgcgt gtggcggctg ccactgcttt aatactttta gaggccctca 3240 aaatcacaag ctatgctcca cttactctct acagttctca taactttcaa aatctatttt 3300 cctcctcaca cttgatgcat atactttctg cccctcagct ccttcagcta tactccctct 3360 ttgttgagtc tcccacaatt accattgctc ctggcccaga cttcaatctg gcctcccaca 3420 ttattccgga taccacacct gatccccatg actgtatctc tcatccatgt gacagtcact 3480 ccatttcccc atatttcctt ctttcctatt tctcatcctg atcacacttg gtttattgat 3540 ggcagttcca ccagggctaa ttgccactca ccagcaaagg caggctatac tatagtattt 3600 tccatgttta tcattgaggc taccactctg cccccctcca ctacttctca gcaaaccgaa 3660 ctcattaatc tctcccactc taggttccca tgctgcccct aatccctttc aaagcagccc 3720 tgagaacatc acccattatc tctccatacc acccccaaaa attttcgcca ccccaacact 3780 tcaccactat tttgttttgt ttttcttatt aatataagaa gacagggatc tcaggcctct 3840 gagcccaagc aaagccatca tatcccctgt gacctgcagg tatacatcca gatggcctga 3900 agcaactgaa gatccacaaa agaagtgaaa atagccttaa ttgatgacat tccacccttg 3960 tgatttgttc ctgccccacc ctaactgata tgacatagtc tctgccgccc ttaaaaaggt 4020 actctgtaat attctcccct gcccttaaga aggtactttg taatattctc ccctgccctt 4080 aagaaggtat tttgtaatat tctccatgcc cttaagaatg tactttgtac gcctatccta 4140 aacctataag aactaatgat aatcgggcag gcacggtggc tcacgtctgt aatcccagca 4200 tttggaaggc cgaggtgggt ggatcatgag gtcaggagat caagaccacg gtgaaaccct 4260 gtctctacta aaaatacaaa agaaaaaaaa ttagccaggc atggtggcgg gcgcctatag 4320 tcccagctac tcaggaggct gaggcaggaa aatggcatga acccgggagg cagagcttgt 4380 agtgaaccaa gactgagcca ctgcactcta gcctgggcaa cacagcaaga ctctgtctca 4440 aaaaaaaaaa aaaaaagaac taatgataat cccaccaccc tttgctgact cctttttgga 4500 ctcagcccac ctgcacccag gtgaaataaa cagccttgtt gctcacagaa agcctgtttg 4560 gtggtctctt cacaaggatg cgcgtga 4587 <210> 212 <211> 465 <212> DNA <213> Homo sapiens <400> 212 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgtag gtacacatcc 60 aaatggcctg ttcctgcctt aactgatgac attccaccac aaaaggagtg aaaatggctg 120 gcccttgcct taagtgatga cattccacca caaaataagt gaaaatggct ggtccttgcc 180 ttaactgatg acattacctt gtgaaatccc ttttccgggc tcatcctgac tcaaaaagct 240 cccccactga gcaccttgtg accccccatg cctgcctgcc agagaacaag ccgcctttga 300 ctgtaatttt cctttaccta cccaaatctt ataaaacagc cccaccccta tctcccttcg 360 ctgattctct ttttggactc atcccgcctg cacccaggtg attaaaaagc tttattgctc 420 acacagagcc tgttttgtgg tctcttcaca tggacgcgcg tgaaa 465 <210> 213 <211> 212 <212> DNA <213> Homo sapiens <400> 213 ttacagtagg tagctaggca ggcatgagca gggcggtgga gggctccccc tcaacacaca 60 ccaggagtgt caggcaacca gcaggtgatg gtcaggcggt tgttaactgt ttctctgaat 120 aattggtcac agccagcggc agggagaggt agtctcctaa tagatagaaa acatctgaaa 180 ctggtcagca gcttcccaat aagatctcag ga 212 <210> 214 <211> 861 <212> DNA <213> Homo sapiens <400> 214 tttccttctt cggtggctag ctatcctgag gggaggaaac tatgtcctca tgcctgcagc 60 taaccattgg aaattactta aaacccttca ccaaaccttt cacttaggta ttgataacac 120 ccatcagatg gccaaatcat tatttactgg acgaggcctt ttcaaaactg tcaagcagat 180 agtcagggcc tgtgaagtgt gccaaagaaa taatcccctg cactgcaggc tatacattta 240 aatccctgta tctttaacct ccttgttaag tttgtctctt ccagaatcaa agttgtaaaa 300 ctacaaattg ttcttcaaat gaagccccag atgcagtcca tgactaagat ccaccgcgga 360 cccctggaca ggcctgctag cccatgttcc gatgctagtg acatcgaagg cacccctccc 420 gaggaaatct caactgcacg acccctacta tgcgccagtt cagcaggaaa cagttagagt 480 ggttgtcggc caaccttccc aacagcactt gggttttcct gtcgagaggg ggaactgaga 540 gacatgacta gctggatttc ctaggccgac taagaatccc taagcctagc tggggaggtg 600 accgcatcca cctttaaaca cggggcttgc aacttagctc acacccaacc aatcaggtag 660 taaagagagt tcactaaaat gctgattagg caaaaacaga aggtaaataa atagccaatc 720 atctatcacc tgagagcaca gggcggggga caatgatcgg gatataaatc caggcattcg 780 agcaggcaac ggcaaccccc tttgggtccc ctcccatttt atggaagctc tgttttcact 840 ctattaaatc ttgcaactgc a 861 <210> 215 <211> 7309 <212> DNA <213> Homo sapiens <400> 215 cccctttggg tcccctcctt atatgggagc tctgttttca ctctatttca ctctattaaa 60 tcttgcaact gccctcttct ggtccatgtt tgttacggct caaactgagc tttcgctcgc 120 cgtccaccac tgttgtttgc cgccttcgca gacccgccgc tgacacccat ccctctgaat 180 ccggcagggt gtctgctgtg ctcctgatcc agtgaggcgc ccattgccac tcccgattgg 240 gctaaaggct tgccattgtt cctgcatggc taagtgcctg ggttcgtcct aatcgagctg 300 aacactagtc actgggttcc atggttctct tccgtgaccc acgacttcta atagagctat 360 aacactcacc gcatggccca agattccatt ccttggaatc tgtgaggcca agaaccccag 420 gtcagagaac acggggcttg ccaccatctt ggaagtggcc cgccgccatt ttggaagtgg 480 cccaccacca tcttgggagc tctgtgagca aggacccccc ggtaacattt tggcgaccac 540 gaagggacct ccaaagcggt gagtaatatc ggaccacttt cacttgctat tctgtcctat 600 ccttccttag aactggagga aaataccagg cacctgtcgg ccagttaaaa acgattagca 660 tggccacagg acttaagact caggtgtgag gctatctggg gaagggattt ctaacaaccc 720 ccaacccttc tattggggac gttggtctgc ctcgcgccgg cttccacttt cagttttctt 780 ggggaagcca agggccgcct agagacagaa agctgttgtc ctgaactccc ggcagtagcc 840 ggttgagatc atggcacagc cagaagtctc tactcagcag tcgcctgtgc atgcgcccca 900 cctttccttc tgacccatac ctcctgggtc ccgaccacga ctttcttgaa agtgtagccc 960 caaaattctc cttacctctg aatctacttc ctctgatccc tgcctcctag gtactaatgg 1020 ttcagacttt catttcctct agcaagtcgt atctccaagg ggatctaagg aagctctacg 1080 ctgcgtcctt aggcagctag actataaccc aggcagtctt atccctggtg tccctcccga 1140 tttaggtata cagctcttga catgggcagt tatgggcagt tatgtgggac ccgttcccca 1200 ccacccttgc cagggcccca agtttgtaat ggctaagaga gagagactga gagagcgaga 1260 gagagagacg gagagagaga gatggagaga gggacaaaga cagagtcaaa gacagaaaga 1320 aagaaaaaga tagaaatagt tttaaaaaaa aagtgtgccc tattccttta aaagccaggg 1380 taaatttaaa acctgtaatt gataattgaa ggtcttctcc gtgaccctat aacacttcaa 1440 tgccactttg ttgtcaatgt aaataagggc gtagcccaaa agcactgagg ccactgacaa 1500 cctgtagctt tcctatcaaa aatccttaac ccagtaaccc gcggatgggc caaatgcatt 1560 cggtcggtag cggcaattgc tttgctaaaa gtagaaaagg aactttttga ggaaacttcg 1620 ttgacagcac acctcaccag ttaaactatt ctaagtcaaa aaaaaaaaaa aagcaaaaag 1680 gtagcttact aaatcaaaaa tcttaaagta tggggctatt gtgttagaaa agggtaatgt 1740 aactccaacc actgataatt cccttaaccc agcagatttc ctaacagggg atttaaatct 1800 taattaccat acaaaggtcc gaccagacct aggaggaact cccttcagga ccggaggata 1860 gatggttcct cccaggcgat tgaggagaaa accacaatgg gtattcagta attgatacag 1920 agactggtgt ggaagcagag tgagaaaaat tgcctaataa ttggtctcct caaacatgtg 1980 agctgtttgc actcagccaa gccttaaagt acttacagaa tcaaaagact atctcaatcc 2040 tgaatcaaaa ggttcgctac accctctctg aaatgaattt acataagaat tgttttttat 2100 aggaatgcat cttgatgggg cagctgggtt gttatgaaat actcaagaac ccagcccagc 2160 tctaggactc acccctgagt gcaaaggcaa tgttgggcac gctggcaaag gaccactaga 2220 atccagcagc ccagacccct ttgtttgtgg tcaagagagg cgggaaaaca ggtgcaggac 2280 tgctacattg gtgagcataa ctaatccgat aagcagaggt ccatgggtgg ttacgcaccc 2340 tggaaaggat ctcacccctg agcccaaagg caatgttggg cacgctggta aaggaccact 2400 agaatccagc agcccggacc cctttctttg tggtcaagag aggcgggaaa acaggtgcag 2460 aactgctaca tcagttagca taactaatcc aataagcaga ggtccatggg tggttatgca 2520 ccctggaaaa gaataaacat taggccctta gaggatgctc taggactaac gctcgatgga 2580 aaatgactaa gggtgctggc acccctatgt ccttttttca gatgggaaat gttcccccca 2640 ccccaaggca gaaatgcccc tgagatgtat tctggagaat taggaccaat ttgaccctca 2700 gacgctaaga aagaaatgac ttatattctt ctgcagtacc gcctggccac gatatcctct 2760 tcaaggggca gaaacttggc ctcctgaggg aagtataaat tataacacca tcttacagcc 2820 agacctcttc tgtagaaagg agggcaaatg gagtgaagtg ccatatttgc aaactttctt 2880 ttcattaaga gacaactcat aattatgtaa aaagtgtggt ttatgtccta caggaagccc 2940 tcagattcta cctccctatc ccagcatccc cctgactcct tccccaaata ataaggaccc 3000 cccttttacc cgaatggtcc aaaggagata gacaaatgga taaacgatga acaaaacagt 3060 gccaatattc cctgattttg ccccctccaa gcagtgggag gaggagaatt tggcccagcc 3120 agagagtgca tgtatctttt tctctctcag acttaaagca aattaaaata gacctaggta 3180 aattctcaga taaccctgat ggctatattg atgttttaca aaggttgggg caatcctttg 3240 atctgacatg gagagatatc atgttactgc taaatcagac actaacccca aatgagagaa 3300 gtgccgccat aagtgcagcc tgagagtttg gcaatctctg gtatctcagc caggtcaatg 3360 ataggatgac aacagaggaa agaacgattc accacaggcc agcaggcagt tcccagtgta 3420 gaccgtcact gggacacaga atcagaacat ggagattggt gccacagaca ttcgctaact 3480 tgcgtgctag gactaaggaa aactaggaag aagcttatga attattaaat gatatccact 3540 ataacaccca ctataacagg gaaaggaaga aaatcctact gcctttctgg agagactaag 3600 ggaggcattg aggaagcata cctctctgtc acctgactct attgaaggcc aactaatctt 3660 gaatgataag tttatcactc cgtcagctgc agacattaga aaaaacttca aaagtccacc 3720 ttaggcccag agcaaaactt agaaacccta ttgaacttgg caacctcggt tttttataat 3780 agagatcagg aggagcaggc agaatgggac aaacgggatt taaaaagggc caccgcttta 3840 gtcacggccc tcaggcaatc agactttgga ggctctggaa aagggaaaag ctgggcaaat 3900 caaatgccta atagggctta tttccagtgt ggtctacaag gacactttaa aaaagattgt 3960 ccaagtagaa ataagccacc ccctcgtcca tgccccttat gtcaagggaa tcactggaag 4020 acccattgcc ccaggggatg aaggtcctct gagtcagaag ccactaacca gatgatcctg 4080 cagcaggact gagggtgccc agggcaagca ccagcccatg ccatcaccct catagagccc 4140 tgggtatgct tgaccattga gggccaggag gttaactgtc tcctggacac tggcacggcc 4200 ttctcagtct tactcgcctg tcccggacaa ctgtcctccg catctgtcac tatccaaggg 4260 gtcctaggac aggcagtcac tagatacttc tcccagccac taaattgtga ctggggaact 4320 ttactctttt cacatgcctt tctaattatg cctgaaagcc ccactccctt gttagggaga 4380 gacattgtag caaaagcagg ggccattata catctgaacg taggaaaagg aacacctgtt 4440 tgttgtcccc tgcttgagga aggaattaat cctgaagtct gagcaacaga aggacaacat 4500 agatgagcaa agaatgccca tcctgttcaa gttaaactaa aggattccac ctcctttcct 4560 tactgaaggc agcaccccct cagacccgag gcccaacaag gactccaaaa gattgttaag 4620 gacctaaaag cccaaggcct agtaaaacca tgcaatagcc cctgcaatac tccaatttta 4680 ggagtacaga aacccaatgg acagtggagg ttagtgcaag atctcaggat tatcaatgag 4740 gctgttgttc ctctataccc agctgtacct aacccttata ctctgctttc ccaaatacca 4800 gaggaagcag agtggtttac agtcctggac cttaaggatg cctttttcgg catccctgta 4860 catcctgact ctcaattctt gtttgccttt gaagatccaa tgtctcaact cacctggact 4920 gttttacccc aagggttcaa ggatagcccc cgtctatttg gccaggcatt agcccaagac 4980 ttgagccaat tgtcatagct ggacattctt gttcttcagt atggggatga tttaattata 5040 gccacccatt cagaaacctt gtggcatcaa gccacccaag cgctcttaaa tttcctcgct 5100 acctgtggct ccaaacaaaa ggctcagctc tgctcacagc aggttaaata cttagggcta 5160 aaattatcca aagtcaccag ggccctcaga gaggaacgta tccagcgtat actggcttat 5220 cctcatccca aaaccctaaa gcaactaaga gggttccttg gcataacagc cttctgccga 5280 atatggattc ccagatacag tgaaatagcc aggccattat gtacattaat taaggaaact 5340 cagaaagcca atacccatat agtaagatgg acacctgaaa cagaagtggc tttccaggcc 5400 ctaaagaagg ccctaaccca aaccccagtt gtaagcttgc caacggggca agacttttct 5460 ttatatgtca cagaagaaac aggaatagct ctaggagtcc ttacgcaggt ctgagggatg 5520 agcttgcaac ccgtggtata cctgagtaag gaaattgatg tagtggcaaa gggttggcct 5580 cattgtttat gggtaatggt agcagtagca gtcttagtat ctgaagcagt taaaataata 5640 cagggaagag atctttctgt gtggacatct catgatgtga acggcatact cactgctaaa 5700 ggagacttgt ggctgtcaga caaccgttta cttaaatatc aggctctatt acttgaagag 5760 ccagtgctgc gactgcgcac ttgtgcaact cttaacccag ccacatttct tccagacaat 5820 gaagagagga aagaacataa ttgtcaacaa gtaattgctc aaacctatgc cactcaaggg 5880 gaccttttag aggtgccctt gactgatcac gacctcaact tgtatactga tggaagttcc 5940 tttgtagaaa aaggacttca aaaagcaggg tatgcagtgg tcagtcgtaa tggaatactt 6000 gaaagtaatc ccctcactcc aggaactagt gctcagctgg caaaactaat agccctcact 6060 caggcactag aattaggaga agggaaaagg gtaaatatat atacagactc taagtatgct 6120 tacctagtcc tccatgccca tgcagcaata tggagagaaa gggaattcct aatttccgag 6180 ggaataccta tcaaacatca ggaagccatc aggagattac tattggctgt accgaaacct 6240 aaagaggtgg cagtcttaca ctgccggggt caccaggaag gaaaggaaag ggaaatagaa 6300 aggaaccacc aagcggatat tgaagccaaa agagccacaa ggcaggaccc tccattagaa 6360 atgcttatag aaggacccct agtatggggt aatcccctcc aggaaaccaa gccccagtac 6420 tcggaagaag aaatagaatg aggaacctca tgaagacata gtttcctccc ctcaggatgg 6480 ctagccaccg aagaaggaaa aatacttatg cctgcagcta accagtggaa attacttaaa 6540 acccttcacc aaacctttca cttatgcatt gatagcaccc atgagatggc caaattatta 6600 tttactgcac caggcctttt caaaactatc aagcagggcc tctatagtgt gccaaagaaa 6660 taatcccctg cattgcagac catacatttc aatccctgta tctttaacct ccttgttaag 6720 tttgtctctt ccagaattga aactgtaaaa ctacaaatca ttcttcaaat ggagccccag 6780 atgcagtcca tgactaagat ccactgcaga cccctgatca acctcctagc ccatgctcca 6840 atgttaatga cattgaaggc acccctcccg aggaaatctc aactgcacaa cccctactat 6900 gacccaattc agcaggaagc agttagagca gtcatcagcc aacctcccca acagcacttg 6960 ggttttcctg ttgagagggg ggactgagag acaggactag ctggatttcc taggccgact 7020 aagaatccct aagcctagct gggaaggtga ccgcatctac ctttaaacat ggggcttgcc 7080 acttagctca cacccaacca atcagagagc tcactaagaa gctaattagg caaaaatagg 7140 aggtaaagaa atagccaatc atcaattgcc tgagagcaca gtgggaggga caaggatccg 7200 gatataaacc caggcatttg agacagcaat ggcaatcccc tttgggtccc ctccttgtat 7260 gggagctctg ttttcactct atttcactct attaaatctt gcaactgca 7309 <210> 216 <211> 951 <212> DNA <213> Homo sapiens <400> 216 gtggggaaaa gaaagagaga tcagactgtt actgtgtcta tgtagagaga agtagacata 60 agagactcca ttttgttctg tactaagaaa aattcttctg ccttgggatg ctgttaatct 120 gtgaccttac ccccaaccct gtgctccctg aaacatgtgc tgtgtcaact cagggttaaa 180 tggattaagg gcggtgcaag atgtgctttg ttaaacagat gcttgaaggc agcatgctcc 240 ttaagagtca tcaccactcc ctaatctcaa gtacccaggg gcacaaacac tgcggaaggc 300 tgcagggacc tctgcctacg aaagccaggt attgtccaag gtttctcccc atgtgacagt 360 ctgaaatatg gcctcctggg aagggaaaga cctgaccgtc ccccagcccg acacccgtaa 420 agggtctgtg ctgaggagga ttagtaaaag aggaaggaat gcctctttgc agttgagata 480 agaggaaggc atctgtctcc tgctcgtccc tgggcaatgg aatgtctccg tgtaaaaccc 540 gattgtatat tccatctact gagacagggg aaaaccgcct tagggctgga ggtgggacat 600 gcgggcagca atactgctct ttaaggcatt gagatgttta tgtatatgca catcaaaagc 660 acagcacttt tttctctaac ttgtttatga tgcagagaca tttgttcaca tgttttcctg 720 cagaccctct ccccactatt accctattgt cctgccacat cccgctctcc cagaaatgcc 780 cgataatgat cgataaatac tgagggaact cagaggctgg tgccggcgcg ggtcccctgc 840 gcccactttt ccttctctat actttgtctc tgtgtatctt tcttttctca agtctctcgt 900 tccacccaac aagaaacgcc cacaagtgtg gaggggcagg ccaccccttc a 951 <210> 217 <211> 441 <212> DNA <213> Homo sapiens <400> 217 gtcaggcctc tgagcccaag ctaagccatc gcatccccgg tgacttgcac atatacgccc 60 agatggcctg aaataactga agaatcacaa aagaagtgaa aatgccctgc cccgccttaa 120 ctgatgacat tccaccacaa aagtgaaaat ggccggtcct cgccttaagt gatgacatta 180 ccttgtaaaa gtccttttcc tggctcatcc tggctcaaaa agctcccctg agcaccttgc 240 cccactcctg cccgccagag aacaactccc ctttgactgt aattttcctt tacctaccca 300 aatcctataa aacggcccca cccctatctc ccttcgctga ctctcttttc ggactcagcc 360 cgcctgcacc caggtgatta aaagctttta ttgctcacac aaagcctgtt tggtggtctc 420 ttcacacgga cgcgcatgaa a 441 <210> 218 <211> 5839 <212> DNA <213> Homo sapiens <400> 218 caggcctctg agcccaagcc aagccatcgc atcccctgtc acttgcacgt atacacccag 60 atggcctgaa gtaactgaag aatcacaaaa gaagtgaata cgccctgccc tccttaactg 120 atgacattcc accacaaaag aagtgcaaac ggccggtcct tgccttaact gatgacatta 180 ccttgtgaaa gtccttttcc tggctcatcc tggctcaaaa agcaccccca ctgagcacct 240 tgcaaccccc actcctgccc tccagagaac aacccccctt tgactataat tttcctttac 300 ctacccaaat cctataaaac agccccaccc ctaactccct tcgctgactc tctttttgga 360 ctcagcccgc ctgcacccag gtgaaataaa cagccacgtt gctcacacaa agcctgtttg 420 gtggtctctt cacacggatg cgcatgaaat ttggtgctgt gactcggatt gggggacctc 480 ccttgggaga tcaatcccct gtcctcctgc tctttgctcc atgagaaaga tccacctatg 540 acctcaggtc ctcagactga ccagcccaag aaacatctca ccaatttcaa atccggtaag 600 tggcctcttt ttactctctt ctccaacctc cctcactatc cctcaacctc tttctccttt 660 caatcttggc gccacacttc aatctctcct ttctcttaat ttcaattcct ttcatttttt 720 ggtagagaca aaggagacac attttatccg tggacccaaa actccggcgc cggtcacgga 780 ctgggaaggc agctttccct tggcgtttaa tcattgcagg gacacctctc tgattattca 840 cccacgtttc aagggtgtca gaccacgcag ggatgcctgc cttggtcctt cacccttagc 900 agaaagtccc gcttttcagg ggaaggggca agtaccccaa ccccttctct ccttgtctct 960 accccttctc tgcttttcca gggaaaaggc aagtacccct tctctccttg tctctacccc 1020 ttctctgctt ttctggggaa agggcaagta ccccaacccc ttctctccat gtctctaccc 1080 cttctctgct tttctggggg aggggcaagt acccctcaac cccttctcct tcacccttag 1140 cggcaagtcc tgctttccta gggggcaaga actccccaat cccttatttc tgaaccccga 1200 cctcttatct ctgtgcccca atcccttatt tctgaacccc aacctcttat ctctgtgccc 1260 caattcctta tttccatggc ccaacccttt ctctgctttt ctggagggca agaacccccc 1320 acctcttcct gtgtctctac tcttttctct gggcttgcct ccttcactat gggcaagttt 1380 ccaccttcca ttcctccttc ttctccctta gcttatattc ttaagaactt aaaacctctt 1440 caactctcac ctgacctaaa atctaagcat cttattttct tctgcaatgc cgcttgaccc 1500 caatacaaac ccgacagtag ttccaaatag ccggaaaatg gcgctttcaa tttttccatc 1560 ctacaagatc taaataattc ttgtcataaa ataggcaaat ggtctgaggt gcctgatgtc 1620 caggcattct tttacacatc agtcccttcc tagtctctgt gcccagtgca gctcatccca 1680 aaccttcctt ctttccctcc tgcctgtccc ctcagtccca accccaagcg tcgctgagtc 1740 tttctaatct tccttttcta cagacccatc tgccctctcc cctcctcgcc aggccaaact 1800 aggtcccaat tctccctcag cctccactcc tccaccctgt aatcttttta ttacctcccc 1860 tcctcacacc tggtcctgct tacagtttca ttctttgact agccctcccc cacctgccca 1920 gcaatttact cttaaaaagg tggttggagc caaaggcata gtcaaggtta atgctccttt 1980 ttctttatcc caaatcagaa gcatttaggc tcttttttat caaatataaa aacccagccc 2040 agttcatggc tcgttcagca gcaaccctga gacactttac agccctagac cctaaaaggt 2100 caaaaggcca tcttattctc aatatacatt ttattaccca atctgctcct gacattaaat 2160 aaaactccaa aaattagaat ctggccctca aaccccacaa caggacttaa ttaacctcac 2220 cttcaaggtg tacaataaca taaaaaagtt gcaattcctt gcctccactg tgagacaaac 2280 cccagccaca tatccagcac acaagaactt ccaaatgcct gaaccacagc ggccaggcat 2340 tcctccagaa cctcctcccc caggagcttg ctacaagtgc cagaaatctg accaccaggc 2400 caaggaatgc ctgcagccca ggattcctcc taagccatgt cccatctgtg cgggacccca 2460 ctggaaattg gactgttcaa ctcacctggc agccactccc agagcccctg gaactctggc 2520 ccaaggctct ctgactgact ccttcttggc ttagcggctg aagactgatg ctgcctgatt 2580 gcctcagaag cccggtagac catcacggat gccgagcttt aagtaactct cacagtggag 2640 ggtaagtcca ttcccttctt aatcaataca gaggctaccc actccacatt accttctttt 2700 caagggcctg tttcccttgc ctccataact gttgtgggta ttgacagcca ggcttctaaa 2760 cctcttaaaa ctcccaactc tggtgccaaa ttagaggata ctcttttatg cactcttttt 2820 tagttatccc cacctgccca gttcccttat taggctgaga tattttaacc aaattatctg 2880 cttacctgac tattcctgga ctatagccgc atctcattgc tgcccttctt cccaatccaa 2940 agcatccttt gcatcctcct ctagtattcc cccaccttaa cccagaagta taagatacct 3000 ctactccctc cttggtgact gatcatgcac cccttaccat ctcattaaaa cctaatcacc 3060 cttaccccac tcaatgccaa tatcccatcc cacagcatgc tgtaaaagga ttaaagcccg 3120 ttatcacttg cctgctacag catgggcttc taaaacctat aaactctcct taccattccc 3180 ccattttacc tgtcctaaaa ccagacaagg cttacaagtt agttcagaat ctgtgcctta 3240 tcaaccaaat tgtttcgtct atccacccca tggtgccaaa cctgtatact ctcctatcct 3300 caatagctcc ctctactacc cattattctg ttctggatct caaacatgct ttctttacta 3360 ttcctttgca cctttcatcc cagcctctct ttgccttcac ttagactgac cctgacaccc 3420 attaggctca gcaaattacc tgggctgtac tgcctcaagg cttcacagac agcccccatt 3480 acttcagtca agcccaaatt tcatcctcat ctgttaccta tctcagcata attctcataa 3540 aaacacacgt gctctccctg ctgatcatgt ctgattaatc tcccaaacct caatccctta 3600 aaaaagagca actcctttct ttcctaggca tggttagtgc ggtcagaatt cttacacaag 3660 ggccaggacc acacagtgta ggctttctgt ccaaacaact tgaccttact gttttagcct 3720 agccctcatg tctgcgtgca gcagctgcca ctgctttaat actgttagag gccctaaaaa 3780 tcacaaacta tgctcaactc actctctaca tttctcataa cttccaaaat ctattgtctt 3840 cctcatacct gacacatata ctttctgctc cccagctcct tcagctgtac tcactcttta 3900 agtcccacag ttaccattgt tcctggccca gacttcaatc tggcctctca cattattcct 3960 gataccacac ctgaccccca tgactgtatc tctctgatcc acctgatatt caccccattt 4020 ccccatattt ccttcttttc tgttcctcac cctgatcacg cttgatttat tgatggcagt 4080 tctaccaggc ctaatcacca cacaccagca aaggcaggct atgctatagt acaagccact 4140 agcccgcctc tcagaacctc tcatttcctt tccatcgtgg aaatctatcc tcaaggaaat 4200 aacttctcag tgttccatct gctattctac tactcctcag ggattattca ggccccctcc 4260 cttccctaca catcaagctc gaggatttgc tgccactcag gactggcaaa ttagcttact 4320 caacatgccc tgattcagga aactaaaata cctcttagtc taaatagaca ctttcactga 4380 ataagtaaag gcctttccta cagggtctga gaaggccacc acagtcattt cttccctcct 4440 gtcagacata attcctcagt ttagccttcc cacctctata cagtctgata acagaccagc 4500 ctttattagt caaatcagcc aagcagtttt tcaggctctt agtattcagt gaaaccttta 4560 tatcccttac ggtcctccat cttcaagaaa agtagaatgg actaaaggtc ttttaaaaac 4620 acacctcacc aagctcagct accaacttaa aaaggactgg acaatacttt taccactttc 4680 ccttctcaga attcaggcct gtcttcggaa tgctacaggg tacagcccat ttaagctcct 4740 gtatagatgc tcctttttat taggccccag tctcattgca gacaccagag caacttagac 4800 tgtgccccag aaaacttgtc atccctgcta tcttctgtct agtcatactc ctatttaccg 4860 ttctcaacta ctcatacatg ccctgctctt gtttacactg ccagtttaca ctgtttttcc 4920 aagccatcac aggtgatatt tcctggtgct atccccaaat tgccactctt aactcttgaa 4980 gtaaataaat aatctttgct ggcaggactc tgctgaatct ccttaggcat tctctaatca 5040 gatatcctga gtcgtcccaa ttcttagacc ttttatacct gtttttctcc ttctcttatt 5100 ccatttagtt tctcaattca tccaaaacca tatccaggcc atcagcaatc attctgtatg 5160 acaaatgttt cttgtaacat ccccacaata tcacccctta ccacaagacc tcccttcagc 5220 ttaatctctc ccactctagg ttcccacaca gcacctaatc ccgcttgaag cagccctgag 5280 aaacatcgtc cactctctct ccataccacc cccccaaaat ttttgccacc ccaacacttc 5340 aacactattt tgttttattt ttcttattaa tataagaagg caggaatgtc aggcctctga 5400 gcccaagcca agccatcgca tcccctgtca cttgcacata tatgcccaga tggcctgaag 5460 taactgaaga atcacaaaag aagtgaatat gccctgcccc accttaactg atgacattcc 5520 accacaacag aagtataaat ggctggtcct tgccttaagt gatgacatta tcttgtgaaa 5580 gtccttttcc tgctcatcat ggctcaaaaa gcacccccca ctgagcacct tgtgaccccc 5640 actcctgccc gccagagaac aacctccctt tgactgtaat tttcctttac ctacccaaat 5700 cctataaaac ggccccaccc ctatctccct tcactgactc tcttttcgga ctcagcccac 5760 ctgcacccag gtgaaataaa cagcctcgtt gctcacacaa agcctgtttg gcggtctctt 5820 cacatggatg cgcatgaaa 5839 <210> 219 <211> 700 <212> DNA <213> Homo sapiens <400> 219 ttatagtagg tagcttgtca gacatgagca gggcagggca gggctcctgc cacccccagc 60 caggaatgtc aggtgaccat caggtaatgg tcaggcagtt atttctctaa gatagtaatt 120 ggctgcagcc tgtgccaggg aaaggcagtc tcccaacaga tagaaacacc tgaaactggt 180 gatcagcagc ttcctgaaaa gatctcagga gttaggtgag tgggttcaag catgcgcact 240 aagaggcaaa atggcagagt ttaactggta catgaccttc taggaacatt ccactggtaa 300 gggaaggata tgcctcaagt gagcatgggt acgactccag taaacacact gtgcatgtgg 360 cccctcccag gtactggaag gccactgcaa atgcttacag accaccccaa gggaagaaca 420 gcaggggaga agtcatgcag aaagagagcc aacataagaa accccaagtc aaaggtcgaa 480 ccgtgcactg gctctctcca gtcgcctgct tggccctctt ccaagtgtac tttacttcct 540 tttgttcctg ctctaaagtt ttaaataata tttcgctcct gctctaaaac ttgccttggc 600 ctctcactct gcattatatc cttcagttga attctttctt ctgaggagtc aagaattgag 660 gttgccgcag acacctgtgg atttgctgcc agtaacaaaa 700 <210> 220 <211> 357 <212> DNA <213> Homo sapiens <400> 220 actgaattac cacaaaagaa gtgaaaatag ccagttcctg ccttaactga tgacattcca 60 ccgttgtgat ttgtttctgc cccaccctaa ctgatcagtt gaccttgtga cattccttct 120 cctggacaat gagtctcaga agctcctcac tggccacctt gtgacccctg cccgcaagag 180 aaaaaccccc tttaactgta atttgccact acctacccaa tcctataaaa ctgccccacc 240 cctatctccc tttgcagact ccttttgcgg actccgtctg cctgcaccca ggtgattaaa 300 aagctttatt gctcacacaa agcctgtttg gtggtctctt cacagggatg tgtgtga 357 <210> 221 <211> 5594 <212> DNA <213> Homo sapiens <400> 221 caggattcca cggatggccc aaatgcattc aatctgtagc agcaactgct ttgttaacag 60 aagaaagtag aaaagtaatt tttgaggaaa cctcattgtg agcacacctc accagtttag 120 aattattcta agtcaaaaaa gcaaaaaggt agcttactaa ctcaaaaatc ttaaagtatg 180 gggctatttt gttagaaaaa ggtgatttaa cattaaccac tgaaaattcc cttaacccag 240 cagattttct aacaggggat ttaaatcttc attaccatac aaaggtccaa ccagacctag 300 taggaactcc cttcagaaca ggatgataga tggttcctcc cgggtgattg agggaaaaaa 360 aaccacaacg ggtattcagt aattgatagg gagactcttg tggaagcaga gttaggaaaa 420 ttgcctaata attggtctgc tcaaacaaga gctgtttgca ctcagccaaa ccttaaagta 480 cttacagaat cgaaaagagt ctatctcaat cttgactcaa aatgttacct acaccctctc 540 tgaagtgaat ttgcataaga actattgttt atgggaatgc atcttgatgg ggcagctagg 600 ttgttatgaa atactcagga actcagccca gctctagaac tcacctctga gcgcaaaggc 660 aatgttgtgc acactggtaa aggaccacta gaatccagca gcccggaccc ctttatctgt 720 ggtcaagaaa ggtgggaaaa caggtgcacg actgctacat tggtgagcat aactaatccg 780 ataagcagag gtccatggat ggttacgcac cctggaaagg aataagcatt aggaccatag 840 aggacactct atgactaatg ctcattggaa aatgactagg ggtgctggca tctctctgtc 900 tttttccaga tgggaaacgt ttccctcaag gcaaaaatgc cccctaagat gtattctgga 960 gaattcggcc cagtcagagt gtatgtatct tttcccctgt cagacttgaa gcaaattaaa 1020 atagacctag gtaaattctc agataaccgt gatggctata ttgatgtttt acaagggtta 1080 ggacaatcct ttgatctgac atggagagat ataatgttac tgctaaatca gacactaacc 1140 ccaaataaga gaagtgccac aataactgca gcccgagagt ttggcgatct ctggtatctc 1200 agtcgggtca atgataggat gaaaatagag gaaagagaac aattccccac aggccagcag 1260 gcagttccca gtgtagaccc tcactgggac gcagaatcag aacatggata ttagtgccac 1320 agacatttac taacttgcgt gccagaagga ctaaggaaaa ctagggagca gcctataaat 1380 ttttcagtga tgtctactat aacacaggga aaggaagaaa atcctactgc ctttctggag 1440 agactaaggg aggcattgag gaagcatacc tctctgtcac ctgactctat tgaaggccaa 1500 ctaatcttaa aagataagtt tatcactcag ccagctgcag acatcagaaa aaaaacttca 1560 aaagtctgct ttaggcccgg agcaaaactt agaaacccta ctgaacttgg caacctcggt 1620 tttttataat agagatcagg aggagcaggc agaacaggac agatgagata agaaaaaggc 1680 caccgcttta gtcatggccc tccaagctga ctttggaggc tctggaacgt ggaaagcctg 1740 ggcaaatcga atgcctaata gggcttgctt ccagtgcagt ctacaaggac actttaaaga 1800 agattgtcga atagaaatga gctgccccct tgtccatgcc ccttatctca agggaatcat 1860 tggaaggccc actgccccaa ggaatgaagg tcgtttgaat cagaagccac taacctgatg 1920 atccagcagc aggactgagg gtgcccgggg caagtgcctg cccataccat caccctcaca 1980 gagctccagg tatgcttgac cattgagggc caggaggtta actgtctcct ggacactggc 2040 atggccttct caatcttact ttcctgtcct atacaactgt cctccagatc tgtcactagc 2100 caaggggtcc taggacagcc agtcactaga tacttctccc agccactaag gtgtgactgg 2160 ggaactttac tcttttcaca tgcttttcta attatgcctg aaagcaccac tctcttgtta 2220 cggagagaca ttctagcaaa agcaggggcc attgtacacc tgaacatagg agaaggaaca 2280 cccgtttgtt gtcccctgct tgaggaagga attaatcctg aagtctggac aacagaagga 2340 caatatggat gagtaaagaa tgcctgtcct gttcaagtta aactaaagga ttccacctcc 2400 tttccctacc aaaggcagta ccctcttaga cccgaggccc aacaaggact ccaaaagatt 2460 gttaaggacc taaaagccca aggcctacta aaaccgtgca acagcccctg caatactcca 2520 attttaggag tacagaaacc caacagacag tggagtttag tgcaagatct caggattatc 2580 agtgaggccg ttgtctctct atacccactg tacctaaccc ttatactctg ctttcccaaa 2640 taccagagga agcagagtgg tttacagtct tggaccttaa ggatgccttt ttctgcatcc 2700 ctgtacatcc tgactctcaa ttcttgtttg cttttgaaga tccttcgaac ccaacatctc 2760 aactcacctg gactgtttta ccccaagggt tcaaggatag cccccatcta tttggccagg 2820 cattagccca agacttgagc cagttttcat acctgaacac tctcatcttt tggtacatgg 2880 atgatttact tttagccacc cgttcagaaa ccttgtgcca tcaagccacc caagcactct 2940 taaatttcct tgccacctgt ggctacaagg cttccaaaca aaaggctcag ctctgctcac 3000 agcagaaata cttagggcta aaattatcca aaggcaccag ggccctcagt gaggaatgta 3060 tccagcctat actggcttat cctcatccca aaaccctaaa gcaactaaga gggttccttg 3120 gcataacagc cttttgctga atatggattc ccaggtacgg cgaaatagcc aggccattat 3180 atgcactcat taaggaaact cagaaagcca atatccattt agtaagatgt acacctgaag 3240 cagaagcagc tttccaggcc ctaaagaagg ccctaaccca agccccagtg ttaagcttgc 3300 caacagggca agacttttct ttatatgtca cagaaaaaaa caggaatagc tctaggagtc 3360 tttacacagg tccaagggaa cagcttgcaa cctgtggcat acctgagtaa ggaaattgat 3420 ttagtggcaa agggttggcc tcattgttta caggtagtgg cagcagtagc agtcttagta 3480 tctgaagcag gtaaaataat acagggaaga gatatgactg tgtggacatc taatgatgta 3540 aacagcatac tcactgctaa agaagacttg tggctgtcag acaactgttt gcttaaatat 3600 caggctgtat tacttgaagg gccagtgctg agaacttctc tcttgtgcaa ctcttaaccc 3660 agccacactt cttccagaca atgaagaaaa gatagaacat aactgtcaac aggtgattgc 3720 tcaaacatac gccactcaag gggaccttct agaggttccc ttgactgatc ccgacctcaa 3780 cttgtatact gatggaaatt cctttgtaga aaaaggactt tgaaaagtgg ggtatgcagt 3840 ggtcagtgat aatggaatac ttgaaagtaa tcccctcact ccaggaacta gcgctcggct 3900 ggcagaacta atagccctca ctggggcacc agaattagaa ggaaaaaggg gaaatatgta 3960 tacagactct aatatgctta cctactcctc catgcccaca cagcaatatg gagagaaagg 4020 gaattcctaa cttctgaggg aacacctatc aaacatcagg aagccattag gagattatta 4080 ttcactgtac agaaacctaa agatgtggca gtcttacact gccggggtca tcagaaagga 4140 aagtaaaggg aaatggaaga gaaccaccaa gcggatattg aagcccatca acagccacaa 4200 ggcaggaccc tccattagaa atgcttatag aaggacccta gtatggggta atcccctctg 4260 ggaaactaag ctccagtact cagcaggaga aatagaatgg ggaacctcac aaggacatag 4320 tttcctcccc tcaggatggc tagccaccga agaaggaata acacttttgc cggcagcgaa 4380 ccaatggaaa ttgcttaaaa cccttcacca gacctttcac ttaggcattg atagcaccca 4440 ccagatggcc aaattattat ttactggacc aggccttttc aaaactatca agcagatagt 4500 cagggcctgt gaagtgtgcc aaagaaataa ccccctgcac tgccggccat acatttcaat 4560 ccctgtatct ttaacctccc tgttaagttt gtttcttcca gaatcgaagc tgtaaaacta 4620 caaatcattc ttcaaatgga accccagatg cagtccatga ctaagatcta ctgcggaccc 4680 ctggaccggc ttgctagccc atgctccaat gttgatgaca ttgaaggccc ccctcctgag 4740 gaaatctcaa ctgcacgatc cctactatgc cccaattcag caggaagcag agcagtcgtc 4800 ggccaacctc cccaacagca ctggggtttt cctgttgaga ggggggactg agagacagga 4860 ctagctggat ttcctaggcc gactaagaat ccctaagcct agctgggagg gtgccgcatc 4920 cacctttaaa cacggggcct gcaacttagc tcacacccaa ccaatcaggt agcaaagagc 4980 gctcactaaa atgctaatta ggcaaaacag gaggtaaaga aatagccaat catctatcac 5040 ctgagagaca atgattggga tataaaccca ggcatttgag ccagcaatgg caaccccctt 5100 tgggtcccct tccattgtgt gggagctctg ttttcactct attacatctt gcaactgaac 5160 attcttctgg tccgtgtttg taacagcttg agctgagctt tctctcactg tccaccactg 5220 ctgtttgtcg ccattgcaga cccgccactg acttccgccc ctctggatcc ggcagggtgt 5280 tggctgcact cctgatccag tgactcaccc attgctgctc ctgatcgggc taaaggcttg 5340 ccattgttcc tgcatggctg agtgcctggg ttcttcctaa tctagctgaa cactagtcgc 5400 tgggttctat ggttctcttt tgtgacccac agcttctaat aaagctataa cactctctgc 5460 atggcccaag attccattcc ttggaatcca tgaggccaag aaccccaggt tagagaacaa 5520 gaggctggct gccatcttgg aagcggcctg ccaccatctt gggagctcta agaacaagga 5580 cccccaggta acat 5594 <210> 222 <211> 5621 <212> DNA <213> Homo sapiens <400> 222 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac gtacacatcc 60 agatggccag ttcctgcctt aactgatgac attccaccac aaaagaagtg aaaatggcct 120 gttcctgcct taactgatga cattatcttg tgaaattcct tctcctggct catcctggct 180 caaaagctcc cctactgagc accttgtgac ccccactcct gcctgccaga gaacaacctc 240 cctttttcct ttacctaccc aaatcctata aaatggcccc acccctatct cccttcactg 300 actcagcctg cctgaaccca ggtgaaataa acagctttat tgctcacaca aagcctgttt 360 ggtggtctct tcacatggac gcaagtgaaa tttggtgctg taactcggat cgggggacct 420 cccttaggag atcaatcccc tgtcctgctc tttgctccgt gagaaagatc cacctacgtt 480 caggtcctca gaccgacgac cccaagaaac atctcaacaa tttcaaatcc ggtaagcagc 540 ctgtttttag tctcttctcc aacctccctc actatccctc aacctctttc tcctttcaat 600 cttggtgcca cacttcaatc tctcccttct cttcatttca attcttttca ttttctggta 660 gagacaaagg agacacgttt tatccgtgga cccaaaactc ctgcaccggt cacagactag 720 ggaaggcagc cttcccttgg tgtttaatca ttgcagggac gcctttctga ttgttcaccc 780 aggtttcaga ggtgtcagac cacacaggga cacctgcctt ggtccttcac ccttaatggt 840 aagtcctgct tttctggggg aaaggcaaga aacctaaccc cttctctcca tgtctctacc 900 ccttctctgc ttttctgggg gaggagcaag aacccctcaa ccccttctcc ttcaccctta 960 gcggcaagtc ctgcttttct gggggaggga caggaactct gacctcttat ctctgtgccc 1020 cgatccctta tttccacccc ccaacctctt atctctgtgc cccgatccct gatttctgtg 1080 ccccgacctc ttatctctgc accccaaccc cttatttccg tgcctcgacc ccttctctgc 1140 ttttctggag ggcaagaacc ccccacccct tctccgtgtc tctactgtct ttcctctggg 1200 cttgcctcct tcactatggg caagcttcca ccttccattc ctccttcttc tcccttagcc 1260 tgtgttctta agaacttaaa acctcttcaa ctctcacctg acctaaaatc taagtgtctt 1320 attttcttct gcaatgccac ttgaccccaa tacaaactcg acagtagttt caaatagctg 1380 gaaaacggca ctttcaattt ttccatccta caagatctaa ataattcttg tcgtaaaata 1440 ggcaaatggt ctgagatgcc tgacatccag gcattctttt atacatcggt ccctctctag 1500 tctctgttcc caatgcaacc cctcccaaat cttccttctt tccctcccac ctgtcccctc 1560 agtcccaacc ccaagcattg ctgagtcttt ctaatcttcc ttttctacag acccatctga 1620 cctctcccct cctcaccagg ccaagctagg tcccaattct tcctcagcct ccgctcctcc 1680 actctataat ccttttatca cctcttctca cacccagtct ggcttacagt ttcgttccgt 1740 gactagccct cccccacctg cccagcaatt tactcttaaa aaggtggctg aagctaaagg 1800 catagtcaag gttaatgctc ctttttcttt atctcaaatc agatagcatt taggctcttt 1860 ttcatcaaat ataaaaatcc agcccagttc atggctcatt tggcaacaac cctgagacgc 1920 tttgcagccc tagaccctaa aaggtcaaaa ggccgtctta ttctcaatat acattttatt 1980 acccaatctg ctcccaacat taaataaaac tcgaaaaatt aaattccagc cctgaaaccc 2040 cacaatagga cttaattaac ctcaccttca aggtgtacaa taatagagta aaggcagcca 2100 agtagcaaca tatttctgag ttgcaattcc ttgcctccac tgtgagacaa accccagcca 2160 catctccagc acacaagaac ttccgaacgc ctaaactgca gtggccaggc attcctccag 2220 aaccgcctcc cccaggagct tgctacaagt gccagaaatc tggccaccat gccaaggaat 2280 gcccacagcc caggattctt cctaagccat gtcccatctg tgcgggaccc cactggaaat 2340 aggactgttc aactcacctg gcagccactc ccagagcccc tggaactctg gcccaaagct 2400 ctctgactga ctccttccca gatcttctcg gcttagcggc tgaagactga tgctgcccga 2460 tcacctcgga agccccgtag atcatcacag acaccgagct ttaggtaact ctcacagtgg 2520 agggtaagtc cgtccccttc ttaatcagta tggaggctac ccactccaca ttaccttctt 2580 ttcaagggcc tgtttccctt gcttccataa ctgttgtgcg tattgacagc caggcttcta 2640 aacctcttaa aactccccaa ctctggtgcc aacttagaca atactctttt aagcactcct 2700 ttttaattat ccccacctgc ccagttccct tattaggccg agacacttta actaaattat 2760 ctgcttccct gactattcct ggactacagc tgcatctcat tgctgccctt cttcccaatc 2820 caaagcctcc tttgcgtcct tctcttatat cccccaacct taacccacaa gtataagata 2880 cctctactcc ctccttggcg accaatcatg caccccttac catctcatta aaacctaatc 2940 acccttatcc tgctcaatgc caatatccca tcccacagca tgctttgaaa ggattaaagc 3000 ctcttatctt ttgcctgcta cagcatggcc ttttaaagct tataaactct ccttacaatt 3060 cccccatttt acctgtccta aaaccagatg agccttacaa gttagttcag gatctgtgcc 3120 ttatcaacca aattgttttg cctatccacc ccatggtgcc aaacccatat actctcctat 3180 cctcaatacc tccctccaca atccattatt ctgtctggat ctcaaacatg ctttctttac 3240 tattcctttg caccgttcat cccagcctct ctttgctttc acttggactg accctaacac 3300 ccatcaggct cagcaaatta cctgggctgt actgctgcaa aggttcacag acagccccca 3360 ttacttaagt gaagcccaaa tttcttcctt atctgttacc tatctcagca taattctcat 3420 aaaaacacac gtgctctccc tgccggtcgt gtccgactaa tctctcaaac cccaacccct 3480 tctacaaaac aactcctttc ctttctgggc atggttggat actttcgcct ttggatacct 3540 ggttttgcca tcctaacaaa accattatat aaactcacaa aaggaaacct agctgacccc 3600 atagatccta aatcttttcc ccattcctct ttccattcct tgaagacagc tttggaggct 3660 gcccccaccc cagctctccc tgactcatcc caaccctttt cattacacac agctgaagtg 3720 cagggctgtg cagtcagaat tcttacacaa ggaccgggat cgcgtccttt ttgtccaaac 3780 aacttgacct tactgtttta ggctggccat catgtctctg tgcagcagct gctgccaccc 3840 taatactttt agaggccctt aaaatcacaa actatgctca actcactctc tacagctctc 3900 ataatttcca aaattgattt tcttcctcac acctgacaca tatactttct gcttcccagc 3960 tccttcagct gtactcactc tttgttgagt ctcccacaat taccattgtt cctgacccgg 4020 acttcaatcc ggcctcccac attattcctg atatcacacc tgaccctcat gactgcatct 4080 ctctgatcca cctgacgttc atctcatttc cccgcatttc cttcttccct gtttctcacc 4140 ctgatcacgc ttggtttatt gatggcagtt ccaccaggcc taatcaccac acaccagcaa 4200 aggcagctat gctatagtac aagccactag cctgcctctt agaacctctc atttcctttc 4260 catcatggaa atctatcctc aaggaaataa attctcagtg ttccatctgc tattctacta 4320 ctcctcaggg attattcagg ccccctccct tccctacaca tcaagctcag ggatttgccc 4380 ccgcccagga ctggcaaatt tgctattcta ctacttctca aggattattc aggccccctc 4440 ccttccctac acatcatgct cagggatttg cccctaccca ggactagcaa attagcttta 4500 ctcaacatgc cctgagtcag gaaactaaaa tatctcttgg tctaggtaga cactttcact 4560 ggataggtag aggcctttcc cacagggtct aagaaggcca ccatggtcat ttcttccctt 4620 ctgtcagaca taattcctcg gtttggcctt cccacctcta tacagtccaa tagcagaccg 4680 gcctttatta gtcaaatcag ccaagcattt tttcaggctc ttagtattca gtgaaacctt 4740 tatatccctt acagtcctca gtcttcagga aagatagaac agactaatgg tcttttaaaa 4800 acacacctca ccaagctcag ccaccaactt aaaaaggact ggacaatact tttaccactt 4860 tcccttctca gaattcaggc ctgtctttgg aatgctacaa ggtacagccc ctttaagctc 4920 ctgtatagac gctccttttt attaggcccc agtctcattc cagacaccag accaacttag 4980 actgtgcccc aaaaaacttg tcatccctac tatcttctgt ctagtcatac tcctattcac 5040 tgttctcaac tactcatgca tgccctgctc ttgtttacac tgccagtttt cactgtttct 5100 ccaagccatc acagctgata tctcctggtg ctatccccaa accgccactc ttaactctta 5160 aagtaaataa ataatctttg ctggcaggac tatgctgaac ctccttacgc actctctaat 5220 cagatagccc aggtcctccc aattcttagt cctttagtac ctgtttttct ccttctctta 5280 ttccatttag tttttcaatt catacaaaac tgtatccagg cctcaccaat aattctaaat 5340 gacaattgtt tcttctaaca accccacaat atcacccctt accacaaaat cttccttcag 5400 cttaatctct cccactctat gttcccacgc tgcccctaat cccactcgaa gcagccctga 5460 gaaacatcgc ccattctctc tccataccac cccccaaaaa ttttcacctc cccaacactt 5520 taccactatt tcattttatt tttcttatta atataagaag acaggaatgt caggcctctg 5580 agcccaagct aagtcatcat atcccctgtg acctgcactc a 5621 <210> 223 <211> 966 <212> DNA <213> Homo sapiens <400> 223 gtggggaaaa gaaagagaga tcagattgtt actgtgtctg tgtagaaagt agaaatacga 60 gactccattt tgttctgtac taagaaaaat tcttctgcct tgagatgctg ttaatctgta 120 accctacccc caaccctgtg ctccctgaga catgtgctgt gtcaactcag ggttaaatgg 180 attaagggct ccgcagggtg tgctttgtta aacaaatgct tgaaggcagc atgctcgtta 240 agagtcatca ccactcccta atctcaagta cccagagaca caaaacactg ctgaagccca 300 cagggacctc tgcctgggaa agccaggtat tgtccaaggt ttctccccat gtgatagcct 360 gagatatggc ctcctgggaa gggaaagacc tgaccacccc cccagcccaa cacctgtaaa 420 gcgtctgtgc tgaggaggat tagtgaaaga ggaaggcctc tttgcaggtg agctaagagg 480 aagtcatctg tctcctgctt gtccctgggc aatggaacgt cttggtgtca agcccgattg 540 tatattccta ctactgagat aagggaaaac caccttaggg ctggaggtgg gacatgctgg 600 cagcaatact gctctttaat ggattaagat gtttatgtgt atgcacatca aaagcacagc 660 acttaattct ttatctggtt taagatgtag agagctttgt tcacgtgttt tcctactgac 720 cttctctccg ctcttaccct attgtcctgc caaatccccc tctctggaaa cgcctgaaaa 780 ttatcaataa atactaaggg aactcagagg ctgctgccgg catgggtcct ccgtattctg 840 aacgcccgtc ccctgggcac tattttcttt ctctatactt tgtctctgtg tctctttctt 900 ttccaggtct ctcattccac ctaatgagaa acgcccacag gtgtggaggg gcaacccacc 960 ccttca 966 <210> 224 <211> 3005 <212> DNA <213> Homo sapiens <400> 224 gttaggcctc tgagcccaag cttagccatc atatcccctg tgacctgcat gtatacatcc 60 agatggcctg aagcaagtga agaatcacaa aagaagtgaa aatggccagt tcctgcctta 120 actgatgact tcccaccatt gtgatttgtt cctgccccac cttaactgag cgattaagct 180 tgtgagattc cttctcctgg ctcagaacct tccccactga gcgccttgtg atccccccca 240 ccacccacct gcaagagaaa aacccctttt gactgtaatt ttccactatg cacccaaatc 300 ctataaaaca gccccacccc tatctccctt tgctgactct ctttgcgaac tcagcccacc 360 tgcacccagg tgattaaaaa gctttattta tcacacaaag cctgtttggt ggtctcttca 420 cacggacgca catgaaattt ggtgctgtga cttagatcag gggacctccc ttgggagatc 480 aatcccctgt cctcctgctc tttgctccat gagaaagatc cacctacaac cttgggtcct 540 cagaccaacc agcccaagga acatctcacc aattttaaat caggtaagcg gtctcttttt 600 actctcttct ccaacctctc tcactatccc tcaacctctt tctcctttca atcttggcac 660 cacccttcaa tctctccctt ctcttaattt cagtttcttt ccttttcact agagacagat 720 gagactcatt ttatccgtga acccaaaact ccggcaccag tcatggactc aggaagacag 780 tcttcgcttg gtgtttaatc actgcggaga cacctggttg attattcact cacatttcag 840 aggtgtctga tcaccgtggg ggcgcctgcc ttgatccttc acctcagtgg caagtaccac 900 ttacctgggg ggcaagcacc cctcacccct tctctccatg tctctaccct ctcttttctc 960 tgggcttgcc tccttcacta tggacaacct tccaccatcc attcctccct cttctccctt 1020 agcctgtgtt ctcaagaact taaaacctct tcaactcaca cctgacctaa aacctttctc 1080 cttatatcat ctcaactccc cccatatttg gacctctcac aatgcaaact actattcctg 1140 tggccactcc tttatgtatc tcttggcaaa gacccactag aatccccctg ggtaaccttt 1200 caccttctcg atgttccttc actcttcatc tccaaagccc aactacacac atcactgaaa 1260 caattggagc cttccagctc cgtattacag ataagccctc tgtcaatact ggcaaactta 1320 aaaacattag cagttattat tgcttaggaa gacacttacc ctgtatttca ctccatcatt 1380 ggctaccttc cccttactcg tcagactctc ctcccaggcc ctcttgttgt ttatttgtac 1440 ccagctccat aaataacagt gaaaggttgc tcataaacac tcaatgtttt cttatgcacc 1500 atgaaaatca aacctccccc tctacgcagt tacctcatca gtccccatta caacctctga 1560 tggctgctgc cctagctgga tccctagaag tctgggcaca agacacatct tttagtactc 1620 cttctcatct ttttactttg catttccagt tttgccttgc acaaggtctc ttcttcctct 1680 gtggatcctc tacctacatg tggctacctg ctaattggac aggcacatgc acactagttt 1740 tccttactcc caaagttcaa tttgcaaatg ggactgaata gcttcctgtt cccctcatga 1800 cactgacatg acacaagaga gttattccac tgattccctt gcttgtcggt ttaggacttt 1860 ctccctccac tattgctctc agtactggaa tagcaggcat ttcatcctct gtcacgacct 1920 ttcgtagcct ctctaatgac ttctctgcta gcatcacaga catatcacaa actctatcag 1980 tccttcaggc ccaagttgac tctcttgctg catttggcct ctaaaaccac cgaggccttg 2040 acttactcac tgctgaaaaa ggaggactct gtatattttt aaatgaagag tgttgttttt 2100 acctaaatca atctggcctg gtgtaagaca acataaaaaa actcaaggat agagcccaaa 2160 aactcatcaa ccaaggaagt aattatgctg aacccccttg ggcactctct aattggatgc 2220 catggatcct cccaattctt agtcctttaa tacctgtttt tctccttctc ttatttggac 2280 cttgtgtctt ccatttagtt tttcaattca tccaaaacca tatccaggcc atcaccaatc 2340 attctatacg acaaatgctc cttctaacaa ccccacaata tcacccctta ccgcaaaatc 2400 ttccttcagc tgaatctctc ccactctagg ttcccatgcc acccctaatc ccacttgaag 2460 cagccctgaa aaacatcacc cattatctct ccataccacc cccaaaaatg ttcactgccc 2520 caacacttca atactatttt atggggtttt tttattgata taagaagaca ggaatgtcag 2580 gcctctgagc ccaaactaag ccatcatatc ccctgtgacc tgcatgtata catccagatg 2640 gcctgaagca agtgaagaat cacaaaagaa gtgaaaatgg ccagttcctg cctcaactga 2700 tgacatccca ccattgtgat ttgttcctgc cccaccttaa ctgagcaatt aaccttgtga 2760 gattccttct cctggctcag aacctccccc actgagcagc ttgtgatccc cgcctctgcc 2820 tgcaagagaa aaaccccctt tgactgtaat tttccactac ccacccaaat cctataaaat 2880 ggccccaccc catctctctt cactgacttt ctttttggac tcaacctgcc tgtacccagg 2940 tgattaaaaa gctttattgc tcacacaaag cctgtttggt ggtctcttca cacggacatg 3000 catga 3005 <210> 225 <211> 668 <212> DNA <213> Homo sapiens <400> 225 ttacagtagg tagtaacaag gcttgagcgg ggcaggaggg agctctccct gctctccacc 60 aggaatgtcg ggccaccatc aggtgatggg caggtggttg ttaactgcct ctctaaaata 120 ataactggtc acagccagcg ccaggaaaag gcagtctccc aatagataga aaaaaaacct 180 gaaactggtg atgcaatcag caggagttca gggagtggac tcaagcatga gctttaagaa 240 gcaaaatggc agagtttact tgttatatga ccttctaggt tcattcgatt tgtaagggaa 300 gaatgcctca cctgagcacg catacaagtc cagtaaacac actgcacttg ctcacctccc 360 aagtgccagc agcccactgc acatgcagac agcccacccc aaggcaagaa tcaggggaga 420 agagatgcaa gaccctagaa atatgccaac cccaagtcag aaggtcaaat agggcacttg 480 atctctcaag tcacccgctt ggccttcttc caagtgtatt ttatttcctt tcattccttc 540 gctaaagctt ttatgataaa cttttactca tgctctattg cctccatctc tcctgcgttc 600 tgcctccttg gttgaattct ttctttggag gaggcaagaa ctgaggttgc tgcagaccca 660 tacggatt 668 <210> 226 <211> 4871 <212> DNA <213> Homo sapiens <400> 226 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac gtatacatcc 60 agatggcctg aagcaactga agatccacaa aagaagtgaa aataacctta actgatgata 120 ctccaccact gtgatttgtt tctgccccac cttaactgat caacgtgctt tgtaatcgcc 180 cccaccctta agaaggttct ttgtatttct ccccaccctt gagaatgtac tttgttagat 240 ccaccccctg ccacaaaaca ccactcctaa ctccaccgcc tatcccaaaa cctgtaagaa 300 ctaatgataa tcccaccacc ttttgctgac tctctttttg gactcagccc gcctgcaccc 360 aggtgaaata aacagccttc ttgctcacac aaagtttgtt tggtggtctc ttcacactga 420 cgcgtgagac atttggtgct gaagacccgg gtcagaggga ctccttcgga agaccagtcc 480 cctgtcctcg cctcactcca tgaggagatc cacctacaac ctcgggtcct cagaccaacc 540 agcccaagga acatctcacc aatttcaaat cgggtaagcg gtcttttcac tctcttctcc 600 agcctctctc gctacccttc aatctccctg cccttccaat tccagttctt tttcctctct 660 agtagagaca aaggagacac attttatcca tggacccaaa actctggcgc cagtcacaga 720 ctcgggaaga cagccttccc ttggtgttta atcattgcag agacgcctgc ctgattattc 780 acccacaatt cactggtgtc tgatcactgc agggacgcct gccttggtca ttcacccaca 840 ttcccatggt ggcaagtcaa ttgcggggat gcctgctttg gctcctcacc cacactgcag 900 cccagggctg ctccccacca ccccgcttct ccgtgtctct acctttctct ttaaacttac 960 cttcttcact atgggcaacc ttccaccctc cattccccct tcttctccct tagcctgtgt 1020 tctcaagaac ttaaaacccc ttcaactcac acctgaccta aaacctaaat gccttatttt 1080 cttctgcaat accgcttgac cccaatacaa actcgataat ggttctaaat agccagaaaa 1140 tccattttac aagatctaga taatttttgt cgaaaaatgg gcaaatggtc tgaggtgcct 1200 gacatccagg cattctttta cacattggtc cctccctagt ctctgctccc aatgcgactc 1260 atcccaaatc tttcttcttt ctctcctgtc tgttccttca gtctccacac caagctctga 1320 gtcctttgaa tcctcctttt ctacagaccc atatgacctc tcctccccag gctgctcctc 1380 aacaggctga gccaggtccc aattcttcct cagcctctgc tccccgaccc tataatcttt 1440 ttatcaactc ccctcacacc cattctggct tacagtttca ttccgcgact agccctcccc 1500 cacctgccca acaatttcct cttaaaaagg tgactggagc tgaaggcata gtcaaggtta 1560 atgttccttt ttctttatcc gacctctccc aaatcagtta gcgtttaggc tctttttcat 1620 caaatataaa aacgcagccc agtccatggc ccgtttggca acaacccttt gacgttttac 1680 tgccctagac ccacaggggc cagaaggctg tcttattctc aatatacatt ttattaacca 1740 gcccactccc aacattaaaa aaagctccag aaattagatt ctggccctca aaccccacaa 1800 gaggacttaa ttaacctcgc cttcaaggtg tacaataata gagtagaggc agccaagtag 1860 caatgtattt ctaagttcca gttccttgcc tccactgtga gacaaacccc agctacattg 1920 ccagcacaca agaactccaa acacctgaag tgcagctgcc aggggttcct ccagaacctc 1980 ttccccagga gcttgcttca agtgccagaa atctggccac tgagccaagg aatgccctgc 2040 agcccgggat tcctccttag ccgtgtccca tttgtacagg accctactgg atatcagact 2100 gtccaactcg cccggcagcc actcccagag cccctggaac tctggcccaa ggctctctga 2160 ctgacttctt cccagatctt ctcagcttag tggctgaaga ccgacgctgc ccgatcgcct 2220 cagaagcttc ctggaccatc acagacgctc tgggtaactc ttacagtgga gggtaagtcc 2280 gtctccttct aaattaatat ggaggctacc cactccacat taccttattt tcaacgacct 2340 gtttcccttg cccccataac tgttgtgggt attgatggcc aggcttctaa acctcttaaa 2400 actccccaac tctgatgcca gcttggacaa cattctttta tgcactcctt tttagttatc 2460 cccacctgcc cagctccctt attagatcaa gacattttaa ctaaattatc tgcttccctg 2520 actattccta agctacagcc acacctcatt gccacccttc ttcccaaccc aaagcctcct 2580 tcacatcttc ctcttgtatc cctccacctt aacgcacagg tacgggacac ctctactccc 2640 tccctagcaa ccgatcacat gccccttacc atcccattaa aacctaatca cccttacccc 2700 gctcaatgcc aatatcccat cccacagcac gatttaaaag gattaaagcc tgttatcact 2760 tgcctgttac agcatggcct tttaaagcct ataaactctc cttacaattc ccccatttta 2820 ccttgtcaaa aacctgacaa gtcttatagg ttagttcagg atctgtgcct tagcaaccaa 2880 attgtcttgc ctagccaccc tgtggtgcca aacccatata ctctatcctc aatacctccc 2940 tccacaaccc attattctgt cctagcaaac ctagctgacc ccatagatcc taattccttt 3000 cgccactcct ctttccattc cttaaaaaca gccctagaag ctgccaccac gctagctctc 3060 cctaactcat cccaaccctt ttcattacac acagccaaag tactgggctc tgcggtcaaa 3120 attcttacac aagagccgga accgtgccct gtagcctttc tgtccaaaca acttgacctt 3180 actattttag gctggccatc atgtctccgt gcagaggctg ccgccgctct aatactttta 3240 gaggccctaa aaatcacaaa ctatgctcaa ctcactctct acagttctca taacttccaa 3300 aatctatttt cttcctccca cctgatgcat atactttctg ctccccggct ccttcagcta 3360 tactcactct ttgggtctcc cacaattacc actgtttctg gcctggactt caatctggcc 3420 tcccacatta ttctggatac cacacctgac ccccatgact gtatctctct gatccacttg 3480 acattcactc catttcccca tatttccttc tttcctcttc cccatcctga tcacactcag 3540 tttattgatg gcagttccac caggcctaat cgccactcac caacaaaggc aggctatgct 3600 atagtatctt ccacatctat cattgaggct accgctctgc ccctctccac tacctctcag 3660 caaggcgaac tcatgcctta acctgagccc tcactcttgc aaaaggacta cgcatcaata 3720 tctatactga ctcgaaatat gccttccata tcctgcacca ccgtgctgtt atatgggctg 3780 aaagaggttt cctcaccgtg caagggtcct ccatcattaa ttcctcttta ataaaaactc 3840 ttctcaaggc cgctttactt ccaaaggaag ctggagtcat tcactgcaag caagggccat 3900 caaaaggtgt cagatctcat cgttcagggc aacgcttatg ctgataaggt agctaaacaa 3960 gcagctagcg ttccaacttc tgcccctcat ggccagtttt tctccttctc gtcagtcact 4020 cccacctact ctgccactaa aacttccacc tatcaatgtc ttcctacaca aggcaaatgg 4080 ttcttggacc aaggaaaata tctccttcca gcctcacagg cccattctat tctgtcgtca 4140 tttcataacc tcttccatgt aggttacaag ccgctagccc atctcttaaa acctctcatt 4200 tcctttccat cgtgaaaatc tatccccaat ccaccactct tgcctccctc ttggagtgga 4260 tagatgatct ttgctgacag aacacactcc aatactttca ccctgatgaa gtcttattct 4320 ttacttttat actcattctt attcttgttc ccgttcttat gccacccact acctctcccc 4380 agctatctct atcacactat caatcgcact cactctctcc tagccatttc taatccttct 4440 ttaacaaaca attgctggct ttgcatttct tttttctcca aaatcaccga ggccctgact 4500 tactcactgc taaaaaaagg ggactccgta tatttttaaa taaagagtgt tgtttttctg 4560 taaatcaatc tggcctggta tatgacaaca taataaaact caaggataga gcccaaaaat 4620 tcgccaacca agcaagtaat tatgctgaac ccccttaggc actctctaat tggatgtcct 4680 gggtcctccc aactctcagt cctttaatac ctgtttttct ccttctttta ttcagacctt 4740 ctaacttctg tttagtttct caattcatac aaaactgtat ccaggccatc accaatcatt 4800 ctatatgaca aatgtttctt ctaacaaccc cacaatatca ccccttacca caaaatcttc 4860 cttcaactta a 4871 <210> 227 <211> 406 <212> DNA <213> Homo sapiens <400> 227 gtcaggcctc tgagcccaag ctaagccatc atatccccct gtgacctgta ggtatacatc 60 cagatggcct gaagtaactg aagaatcaca caagaagtga aatttaaatg gcctgttcct 120 gccttaactg atgacattac cttgtgaaat tccttctcct ggctcatcct ggctcaaaag 180 ctcccccact gagcaccttg tgtcccccgc ccctaccggc cagagaacaa ccccctttga 240 ctgtaatttt cctttaccta cccaaatcct ataaaacagt cccaccccta tctcccttcg 300 ttgactctct ttttggactc agcccgcctg cacccaggtg aaatgaacag ccttgttgct 360 cacacgaagt ctgtttggtg atctcttcac acggacgcga gtgaaa 406 <210> 228 <211> 665 <212> DNA <213> Homo sapiens <400> 228 tagactggta agggaagaat gtctcaaatg agcatgcgta caattccagt aaacacactg 60 agcgtgcggc ccctcccaaa ttctggcagg ccactgcaca tgcggacagc ccagcccaag 120 ggcagaatca ggggagaagg aatgcaagac cctcagaagt atgccagcgt ataaaatccc 180 aagtcagaag gtcaaaccga acacttgatc tctgaagtcg cccgcttggc cctcttccaa 240 gtgtacttcc tttcatttct gctctaaatt ttttattttt tattttttta ttttttttta 300 gacggagtct ctctctgtcg cccaggctgg agtgcagtgg tgtgatctca gctggctgca 360 acctccacct cctgggttca ggcgattctc atgcctcagc ctcccgagta gctgggacta 420 caggtgcctg ccaccacacc tggctaattt ttgtattttt agtagagaca gggtttcgcc 480 atgttggcca ggctggtctc gaactcctga cctcatgtga tctgcctgcc tcggccccct 540 aaagtgttga gattacaggc gtgaaccacc atgcccggcg tgctctaaaa cttgtctcag 600 cctttccttc tgccttatgc cccttagttg aattcttcct tctgaggagg caagaattga 660 ggttg 665 <210> 229 <211> 398 <212> DNA <213> Homo sapiens <400> 229 gtcaggcctc tgagcccaag ataaaccatc atatccccag tgacctgcat gtatacatcc 60 agatggcctg aagtaactaa agaatgacaa aagaagtgaa aatgtattgt tcctgcctta 120 actgatgaca ttaccttgtg aaattccttc tcctggctca tcccggctca aaagctcccc 180 cactgagcac cttgtgaccc ccgcccctgc ccagggagaa ctaccccctt tgactgtaat 240 tttcctttac ctacccaaat gctataaaac ggccccaccc ttatttccct tcactgactc 300 tttttcggac tcagcccgcc tgcacccaga tgaaataaac tgccctgctg ctcacacaaa 360 gcctgtttgg tgatctcttc acacggacac cagtgaaa 398 <210> 230 <211> 5880 <212> DNA <213> Homo sapiens <400> 230 gtcaggcctc tgagcccaag ccaagccatc acatcccctg tgacttgcac gtatacgccc 60 agatggcctg aagaaactga agaatcacaa aagaagtgag tatgccctgg cccaccttaa 120 ttgatgacat tccaccacaa aagaagtgta aatggccagt ccttgcctta agtgatgaca 180 ttaccttgtg aaagtccttt tcctggctca tcctggctca aaaagcaccc ccactgagca 240 ccttgcgacc cctactcctg cccgcgagag aacaaacccc ctttgactgt aattttcctt 300 tacccaccca aatcctataa aacagcccca cccttatctc cctttcgctg actctcttat 360 tttcacctgc ctgcacccag gtgaaataaa tagccatgtt gctcacacaa agcctgtttg 420 gtggtctctt cacacagacg tgcatgaaat ttggcgccgt gactcggatt gggggaactc 480 ccctgggaga tcaatcccct gtcctcttgt tctttgctcc atgagaaaga tccacctacg 540 acctcaggtc ctcagactga ccagcccaag gaacatctca ccaattttaa atcaggtagg 600 tggcctcttc ttactctctt ctccaacctc tctcactgtc cctcaaccac tttcttcttt 660 ccactcttca atctctccct tctcttaatt tcaattcctt tcattttctg ggagagacaa 720 aggagacacg ttttatctgt ggacccaaaa ctccggcgcc agtcacagac tgggaaggca 780 ggcttccctt ggtgtttaat cattgcaggg atgcctctct gattattcac ccacgtttca 840 aaggtgtcag accacgcagg gacgcctgcc ttggtccttc acgcttagca gcaagtcccg 900 cttttctggg gaagaggcaa gtaccccaac cccttctctc cttgtctcta ccccttctct 960 cctttcctgg ggcaggggca agtacccctc aaccccttct ccttcaccct tagtggcaag 1020 tcctgctttt ctgggtgagg ggcaagtacc cctcaacccc ttctccttca cccttagtgg 1080 caagtcccgc ttttctgggg gaggggcaag tacccctcaa ccccttctct ttcaccctta 1140 gcggcaagtc ccgcttttct agggggcaag aacccccaat cccttatttc cgcaccccaa 1200 cctcgtatct ctgtgcccca atcccttatt tccatgccct gaccccttat ttccatgccc 1260 caacccctta tttccatgcc ctgacctctt atctctgtgc cctaacccct tttcccactt 1320 ttctggaagg gaagaacccc caaacccctt ccctccattt ctctactctc ttctctaggc 1380 ttgcttcctt cactataggc aaccttccac cctccattcc tccttctact cccttggcct 1440 gtgttctcaa aaacttaaaa tctcttcaac tcacaactga cctaaaacct aaatgcctta 1500 ttttcttctg caatgccact tgaccccaat acaaactcga ctgtagttcc aaatagccag 1560 aaaatggcac tttgaatttt tccatcctgc aagatctaaa taattcttgt cctaaaatag 1620 gcaaacagtc tgaggtgcct gacgtccagg cattctttta cacatcagtc ccttccttgt 1680 ctctgtgccc agtgcaaatc atcccaaatc ttccttcttt ccctcccgcc tgtcccctaa 1740 gtcccaaacc caagcatcga tgagtctttc taatcttcct tttctacaga cccatctgac 1800 ctctcccctc cttgccaggc ctagctaggt cccaatgctt cctcagcctc cgctcctcca 1860 ccctataatc tttttatcgc ctcccctcct cacacctggt ctggcttaca gtttcgttct 1920 tgactagccc tcccccacct gcccagcaat ttactcttaa aaaggtggct ggagccaaag 1980 gcatagtcaa ggttaatgct cctttttctt tatcccaaat cggatagcgt ttaggctctt 2040 tttcatcaaa tataaaaatc cagcccagtt catgacttgt ttggcagcaa ccctgagaca 2100 ctttacagcc ctagacccta aaaagtcaaa aggccgtctt attctcaaaa tacattttat 2160 tacccaatct gctcccgaca ttaaataaaa ctccaaaaat taaattctgg ccctcaaacc 2220 ccacaacagg atttaattaa cctcaccttc aaggtgtaca atgatagaaa aaagttgcaa 2280 ttccttgcct ccactgtgag acaaacccca gccacatctc cagcacacaa gaacttccaa 2340 acacctgaac cgcagcggcc aggcattcct ctagaacctc ctcccacagg agcttgctac 2400 atgtgccgga aatctggcct ctgggccaag gaatgcccgc agcccgggat tcctcctaag 2460 ccacgtccca tctctgtggg accccactga aaatcggact gttcaactca cctggcagcc 2520 actcccagag cccctggaac tctggcccaa ggctctctga ctgactcctt cccagatctt 2580 ctcggcttag cagctgaaga ctgacactgc ccgatcgcct tggaagcccc ctagaccatc 2640 acggacgcca agcttcaggt aactctcaca gtggaaggta agcccgtccc cttcttaatc 2700 aatacggagg ctacccactc cacattacct tcttttcaag ggcctgtttc ccttgcctcc 2760 ataactgttg tgggtattga cggccaggct tctaaacctc ttaaaactcc ccaactctgg 2820 tgccaactta gacaatactc ttttaagcac tcctttttag ttatccccac ctgcccagtt 2880 cccttattag gctgagacac tttaactaaa ttatctgctt ccctgactat tcctggacta 2940 cagctatatc tcattgccgc ccttcttccc aatccaaagc ctcctttgca tcctcctctt 3000 gtatccaccc cccttaaccc acaagtataa gatacctcta ctccctcctt ggcgaccgat 3060 catgcacccc ttaccatctc attaaaacct aatcaccctt accccactca atgccaatat 3120 cccatcccgc agcatgcttt aaaaagatta aagcctgtta tcactcgcct gctacagcat 3180 ggccttttaa agcctataaa ctctccttac aattccccca ttttacctgt cctaaaacca 3240 gacaagcctt acaagttagt tcaggatctg caccttatca accaaattgt tttgcctatc 3300 caccccgtgg tgccaaaccc atatactctc ctatcctcaa tacctgcctc tataacccat 3360 tattctcttc tagatctcaa acatgctttc tttactattc ctttgcaccc ttaataccag 3420 cctctcttca ctttcacttg gactgaccct gacacccatc aagctcagca aattacctag 3480 gctgtactgc tgcaaagctt cacagacagc ccccattact tcaatcaagc ccaaatttct 3540 tcctcatctg ttacctatct cggcataatt ctcataaatc acacgtgctc tccctgccaa 3600 tcgtgtccga ctgatctctc aaaccccagc accttctaca aaacaacaac tcctttcctt 3660 cctaggcatg gttagcatgg tctgaattct tacacaggag ccaggaccac accctttagc 3720 ctttctgtcc aaacaacttg accttactgt tttagcctag ccctcatgtc tgcgtgcagt 3780 ggctgctgct gctttaatac ttttagaggc cctaaaaatc acaaactatg ttcaactcac 3840 tctctatagt tctcataact tccaaaatct atttgcttcc tcatacctga tgcatatact 3900 ttctgcttcc tggctccttc agctatactc actctttgtt gagtctccca caattaccgt 3960 tgttcctggc ccagacttca atccggtctc ccacattatt cctgatacca cacctgaccc 4020 ccatgactgt atctctctga tccacctgac attcacccca tttccccaaa tttccttctt 4080 tcctgttcct caccctgatc acgcttgatt tagtgatggc gattccacca ggcctaatcg 4140 acacacacca gcaaaggcag gttatgctat agaacaagcc actagcccgc ctctcagaac 4200 ctctcatttc ctttccatcg tggaaatcta tcctcaagga aataacttct cagtgttcca 4260 tctgctattc tactactcct cagggattat tcaggccccc tcccttccct acacatcaag 4320 ctcgaggatt tgccccaccc aggactggca aattagcttt actcaacatg ccctgagtcg 4380 gataactaaa atacctctta gtctagttag atactttcac tggataggta gaggcctttc 4440 ctacagggtc tgagaaggcc accacagtca tttcttccct tctgtcagac ataattcctc 4500 agtttagcct tcccacctca atacagtctg ataacagacg agcctttatt agtcaaatca 4560 gccaagcagt ttttcaggct cttagtattc agtgaaacct ttatatccct tacggtcctc 4620 tgtcttcaag aaaagtagaa tggactaaag gtcttttaaa aacacacctc accaagctca 4680 gccaccaact taaaaaggac tggacaatac ttttaccact ttcccttctc agaattcagg 4740 cccgtccttg gaatgctgca gggtacagcc catttgagct cctgtataga cgctcctttt 4800 tattaggccc cagtctcatt ctagacacca gaccaagtta gactgtgccc caaaaaaact 4860 tgtcatccct actatcttct gtctagtcat actcctattc accgttctca actactcata 4920 catgccctgc tcttgtttac actgccagtt tacactgttt ttccaagcca tcacagctga 4980 tatctcctgg tgctatcccc aaactgccac tcttaactct tgaagtaaat aaataatctt 5040 tgctggcagg actatgctga atctctttag gcactgtcta atcagatgtc ctgagtcgtc 5100 ccaattcttc gatcttttat acctgttttt ctccttctgt tattccattt agtttctcaa 5160 ttcatccaaa accgtatcca ggccatcacc aatcattcta taagacaaat gtttcttcta 5220 acatccccac aatatcaccc cttaccacaa gacctccctt cagcttaatc tctcccactc 5280 taggttccca cgccgcccct aatcccactt gaagcagccc tgagaaacat cgcccattct 5340 ctctccgtac caccccccaa aaattttcac cgccccaaca cttcaacacc attttgtttt 5400 atttttctta ttaatataag aaggcaggaa tgtcaggcct ctgagcccaa gccaagccat 5460 cacatcccct gtgacttgca cgtatacacc cagatggcct gaagtaactg aagaatcaca 5520 aaagaagtga atatgccctg ccccacctta actgatgaca ttccaccaca aaagaagtgt 5580 aaatggccgg tccttgcctt aagtgatgac attaccttgt gaaagtcctt ttcctggctc 5640 atcctggctc aaaagcaccc ccacagagca ctttgtgacc cccactcctg cccgccagag 5700 aataaaccct ctttgactgt aattttcctt tacctacccg aatcctatga aatggctcca 5760 cccttatctc ccttcgctga ctctcttcgg actcagccca cctgcaccca ggtgaaataa 5820 acagccatgt tgctcacaca aagcctgttt ggtggtctct tcacacggac atgcatgaaa 5880 <210> 231 <211> 714 <212> DNA <213> Homo sapiens <400> 231 ttacagtagg tagctaatca gacgtgaaca gggcaggaga ggcatcaacc acaacaaccc 60 ccaccacccc aatcaggaat gtcaggtgac catcagttga tggtcaggca gtttttaact 120 gtctctctaa aataataact ggttgcagct ggtgcaaggg gtgagtcagt ctcccaatag 180 gtaggaaaaa cctgaaactg gtgatcagtg gcttccggat aagaagatct cagggctcac 240 acatgtgcac taagaggcaa aatggtggag tttaattggt atctgacctc taaggacatt 300 cggctggtaa gggaagaatg cctcaagtga gtatgcgtac aactccggta aacacactgc 360 gcatgttctc ctcccaagca ctgacaggcc actgcgcagg cagacagccc accccaagga 420 aagaataagg ggagaaggaa cacaagatcc ggaagtatgc caacgtagaa aaccccaagt 480 caaaaggtca aacagcacat ttgtctttca agtcacccac ttggccctct cccaagtgta 540 ctttccttcc ttttgttcct gctctaaagc attttaataa acttttactc ctgctctaaa 600 acttgcctcg gcctctcctt ctgccttatg cccccctcag ctgaattctt tcttctgagg 660 aggcaagaat tgaggttgcc gcaggcctgt atggatttgc agccgtaaca atac 714 <210> 232 <211> 2158 <212> DNA <213> Homo sapiens <400> 232 tgcagtcaga attcttacac aagagccaga accacaccct gtagcctttc tgtccaaaca 60 acttgacctt actgttttag cctagccatc atgtctccgt gcagcagctg ctgccgccct 120 aataatttta gaggccctca aaatcacaaa ctatgctcaa cttactctct acatttctca 180 taacttccaa aatctatttt cttcctcata cctgatgcat atactttctg ctccccggct 240 ccttcagctg tactcactct ttgttaagtc ccacaattac cattgttcct ggcccggact 300 tcaatccggc ctcccacatt attcctgata ccacacctgg cccctatgaa tgtatctctc 360 tgatccacct gacattcacc ccatttcccc atattgcctt ccttcctgtt cctcaccctg 420 atcacacttg atttattgat ggcggttcca ccaggcctaa tcgccacaca ccagcaaagg 480 caggctatgc tatagtacaa gccactagcc cgcctcttag aacctctcat ttcctttcca 540 tcgtggaaat ctatcctcaa ggaaataact tctcagtgtt ccatctgcta ttctactact 600 cctcagggat tattcaggcc ccctcccttc cctacacatc aagctcaagg atttgccccc 660 gcccaggact ggcaaattag ctttactcaa catgccccga gtcacaaaaa ctaaaatacc 720 tcttagtcta agtagacact ttcactagat aggtagaggc ctttcccaca gggtctgaga 780 aggccaccgc agttatttct tcccttctgt cagatataat tcctcagttt agccttccca 840 cctctataca gtctgataac agatcagcct ttattagtca aatcagccaa gcagtttttc 900 atgctcttag tattcagtga aacctttata tcccttacag tcctcagtct tcaggaaaag 960 tagagcagac taaaggtctt ttaaaaacac acctcgccaa gctcagccac acacttaaaa 1020 aggaatagac aatactttta ccactttccc ttctcagaag tcagacctgt cctcagaatg 1080 ctacaaggta cagcccattt gagctcctgt atagacgttc ctttttatta ggccctagtc 1140 tcattccaga caccagacca acttagtctg tgccccaaaa aaacttgtca tccctactat 1200 cttctgtcta gtcatactcc tattcactgt tctcaactac tcatacatgc cctgctcttg 1260 tttacactgc cggtttacac tgtttctcca agccatcaca gctgatatct cctggtgcta 1320 tccccaaact gccactctta actcttgaag taaataaata atctttgctg gcaggactat 1380 gctgaatctc cttaagcact ctctaatcag atgtcctgag tcgtcccaat tcttagacct 1440 tttatacctg tttttctcct tctcttattc catttagttt ttcaattcat acaaaactgt 1500 atccaggcca tcaccaataa ttctaaatta caaatgttcc ttctaacaac cccacaatat 1560 caccccttac cacaaaatct tccttcagct taatctctcc cactctagct tcccacaccg 1620 cccctaatcc cgctcgaagc agccctgaga aacatcgccc attatctctc cataccatcc 1680 cccaaaattt tcgctgtctc aacactttac cactatttcg ttttattttt cttattaata 1740 taagaagaca ggaatgtcag gcctctgagc ccaagctgag ccatcatatc ccctgtgacc 1800 tgcacgtaca catccagatc gctggttcct gccttaactg atgacattcc accacaaaag 1860 aagtgaaaat ggcctgtttc tgccttaact gatgacatcg tcttgtgaaa ttccttctcc 1920 tggctcatcc tggctcaaaa gctcccccac tgagtacctt gtgaccccca ctcctgcccg 1980 ccagagaaca accccccttt ttcctttacc tacccaaatc ctataaaacg gccccacccc 2040 tatctccctt cgctgactct cttttcggac tcagcccacc tgcacccagg tgaaataaac 2100 agctttattg ctcacacaaa gcctgtttgg tggtctcttc acacagacgc gcgtgaaa 2158 <210> 233 <211> 6351 <212> DNA <213> Homo sapiens <400> 233 gtcaggcctc tgagcccaag ccaaatgaaa tttggtgcca tgactcggct cgggggacct 60 cccttgggag atcaatcccc tgtcctcctg ttctttgctc cgtgagaatg acccacctgt 120 gacctcaggt cctcagaccg accagcccaa gaaacatctc accaatttca aatccggtaa 180 gcggcctctt tttactctct tctccaacct ccctcactat ccctcaacct ctttctcctt 240 tcaatcttgg cgccacactt caatctctcc cttctcttaa tttcaattcc tttcattttc 300 tggtagagac aaaggagaca cgttttatcc atggacccaa ctccggcacc ggtcatggac 360 tgggaaggca gccttccctt ggtgtttaat cattgcaggg acacctctct gattatacac 420 tcacgtttca agggtgtcag accacacagg gacacctgcc ttggtccttc acccttagcg 480 gcaagtcccg attttctgag gaagggacaa gtacccctca accccttctc tccttgtctc 540 taccccttct ctgcttttct ggggcagggg caagaacccc tcaacccttt ctccttcacc 600 cttagcggca agtcccgctt tcctggggca ggggcaagta cccctcaacc ccttctcctt 660 cacccttagt ggcaagtcct gctttcctag ggggcaagaa ccccccaatc gcttatttcc 720 ataccctaac ctcttatctc tgtgccccaa tcccttattt ctgcaccctg acctcttatc 780 tctgtgcccc aatcccttat ttctgtgccc caacaccttc tctgcttttc tggagggcaa 840 gaaccctcca ccccttctcc gtgtctctac tcttttctct gggcttgcct ccttcactat 900 gggtaagctt ccaccttcca ttcctccttc ttctccctta gcctgtgttc tcaaaaactt 960 aaaatctctt caactcacac ctgacctaaa acctaaatgc cttttcttct gcaatgccac 1020 ttgaccccaa tacaaactcg acagtagttc caaatagcca gaaaatggca ctttgaattt 1080 tttcatcctg caaaatctaa ataattcttg tcgtaaaata ggcaaatggt ctgaggtgcc 1140 tgatgtccag gcattctttt acacatcaat cccttcctag tctctgtgcc cagtgcaact 1200 cgtcccaaat cttccttctt tctctcccac ctatcccctc agtaccaacc ccaagcatca 1260 ctgattcttt ctaatcttcc ttttctacag acccatctga cctctctctt cctccccagg 1320 ctgctcctca ccaggccgag ctaggtccca attcttcctc agcctccgct cctccaccct 1380 ataatctttt tatcacctcc cctgtagggg tgggttgccc ctccacacct gtgggtgttt 1440 ctcataaggt ggaacaagag acttaggaaa gaaaaagaca caaagtatag agaaagaaat 1500 aaggggaccc ggggaaccag cgttcagcat atggaggatc cccccagcct ctgagttccc 1560 ttagtattta ttcatcattc gtgggtgttt ctccaagagg gggatgtgtc agggtcacaa 1620 gacaattgtg gggagagggt cagccgacaa acacgtgaac aaaggtcttt gcatcataga 1680 caaggtaaag gattaagtgc tgtgctttta gatatgcata cacataaaca tctcaatgct 1740 ttacaaagca gtattgctgc ccgcatgtcc cacctccagc cctaaggtgg tttttcccta 1800 tctcagtaga tggaacatac aatcgggttt tataccgaga cattccattg cccagggacg 1860 ggcaggagac agatgccttc ctcttgtctc aactgcaaga ggcatgcctt cctcttatac 1920 taatcctcct cagcacagac cctttacggg tgtcggggtg tcgggcgggg ggacagtcag 1980 gtctttccct tcccatgagg ccatatttca gactatcaca tggggagaaa ccttggacaa 2040 tacctggctt tcctaggcag aggtccctgc ggccttccgc agtgtttgtg tccctgggta 2100 cttgagatta gggagtggtg atgactctta acgagcatgc tgccttcaag catctgttta 2160 acaaagcaca tcttgcactg cccttaatcc atttaaccct gagtttgaca cagcacatgt 2220 ttcagagagc acggggttgg gggtaaggtc acagaatctc aaggcagaag aatttttctt 2280 agtacataac aaaatggagt ctcccatgtc tatttctttc tacacagaca cagtgacaat 2340 ctgatctctc ttgcttttcc ccacatcccc tcctcacacc tggtccggct tacagtttcg 2400 ttctgtcccc cacctgccca gcaatttact cttaaaaagg tggctggagc caaaggcata 2460 gtcaaggtta atgctccttt ttctttatcc caaatcggat agcgtttagg ctctttttca 2520 tcaaatataa aaacccagcc cagttcatga cttgtttggc agcaaccctg agacacttta 2580 cagccctaga ccctaaaaag tcaaaaggcc gtcttattct caaaatattt tattacccaa 2640 tctgctcccg acattaaata aaactccaaa aattaaattc cggccctcaa accccacaac 2700 aggatttaat taacctcgcc ttgaaggtgt acaataatag aaaaaaattg caattccttg 2760 cctccactgt gagacaaacc ccagccacat ctccagcaca caagaacttc caaacacctg 2820 aaccacagtg gccaggcgtt cctccagaac ctcctcccac aggagcttgc tacacgtgcc 2880 ggaaatctgg ccactgggcc aaggaatgcc cgctgcccag gattcctcct aagctgcgtc 2940 ccatctgtgt gggaccccac tgaaaatcgg actgttcgac tcacctggca gccactccca 3000 gagcccctgg aactctggcc caaggctctc tgactgactc cttcccagat cttctcagct 3060 tagcggctga agactgacac tgcccgaacg cctcggaagc cccctagacc atcacggatg 3120 ctgagcttcc ggtaactttc acagtggaag gtaaacccat ccccttctta atcaatacag 3180 aggctaccca ctccacatta ccttcttttc aagggcctgt ttcccttgcc tccataactg 3240 ttgcgggtat tgatggccag gcttctaaac ctcttaaaac tccccaactc tggtgccaac 3300 ttagacaata ctcttttaag tactcctttt tagttatccc cacctgccca gttcccttat 3360 taggctgaga cactttaact aaattatctg cttccctgcc tattcctgga ctacaactat 3420 atctcattgc tgcccttctt cccaatccaa agcctccttt gcatcctcct cttgtatccc 3480 cccaccttaa ctcacaaata taagatacct ctactccctc cttggtgacc gatcatgtac 3540 cccttaccat ctcattaaaa cctaatcacc cttaccccac tcaatgacaa tatcccatcc 3600 cgcagcaggc tttaaaaaga ttaaagcctg ttatcactcg cctgctacag catggccttt 3660 taaagcctat aaactcttct tacaattccc ccattttacc tgtcctaaaa ccagataaga 3720 cttacaattt agttcaggat ctgcgcctta tcaaccaaat tgttttgcct atccaccccg 3780 tggtgccaaa cccatatact ctcctatcct caatacctgc ctctacaacc cattattctg 3840 ttctagatct caaacatgct ttctttacta ttcctttgca cccttaatcc cagcctctct 3900 tcgctttcac ttggactgac cctgacaccc atcaagctca gcaaattacc taggctgtac 3960 tgccgcaaag cttcacagac agcccccatt acttcaatca agcccaaatt tcttcctcat 4020 ctgttaccta tctcggcatt tctcataaaa acccacatgc tctccctgcc aatcgtgtcc 4080 aactgatctc tcaaacccaa gcaccttcta caaaacaaca actactttcc ttcctaggta 4140 tggttagcat ggtcagaatt cttacacaag agccaggacc acaacttgta gcctttctgt 4200 ccaaacaact tgaccttact gttttagcct agccctcatg tctgcgtgca gcagctgctg 4260 ctgctttaat acttttagag gccctcaaaa tcacaaactg tgctcaactc tctctctaca 4320 gttctcataa cttccaaaat ctattttctt cctcatacct gatgtatata ctttctgctt 4380 cccggctcct tcagctttac tcactctttg ttgcatctcc cacaattacc attgttcctg 4440 gcccagactt caatccagcc tcccacatta ttcctggtac cacacctgac ccccatgact 4500 gtatctctct gatccacctg acattcacat ttccccaaac ttccttcttt cctgttcctc 4560 accctgatca cacttgattt attgatggcg gttacaccag gcctaatcgc cacacaccag 4620 caaaggcagg tgatgctata gtacaagcca ctagcttgcc tcttagaacc tctcatttcc 4680 ttcccattgt ggaaatctat cctcaaggaa ataacttctc agtgttccat ctgctattct 4740 actactcctc agggattatt caggccccct cccttcccta cacatcaagc tcgaggattt 4800 gccccaccca ggactggcaa attagcttta ctcaacatga cctgagtcag gtaactaaaa 4860 cacctcttag tctaggtaga cactttcact ggataggtac aggcctttcc tacagggtct 4920 gagaaggcca ccacagtcat ttcttccatt ctgttagata taattcctca gtttagcctt 4980 cccgcctcta tacagtctga taacagatga gcctttatta gtcaaatcag ccaagcagtt 5040 tttcaggctc ttagtattca gtgaaacctt tatatccctt atggtcctcc atcttcaaga 5100 aaagtagaat ggactaaagg tcttttaaaa acacacctca ccaagctcag ccaccaactt 5160 aaaaaggact ggacaatact tttaccactt tcccttctca gaattcaggc ctgtcctcag 5220 aatgctacag ggtacagccc atttaagctc ctgtatagac gctccttttt attaggcccc 5280 agtctcattc cagacaccag accaacttag actgtgcccc cgaaaaactt gtcatcccta 5340 ctatcttctg tctagtcata ctcctattca cctttctcaa ctactcatac atgccctgct 5400 cttgtttaca ctgccagttt acactgtttt tccaagccat cacagctgat atctcctggt 5460 gctatcccca aactgccact cttaactctt gaagtaaata aataatcttt gctggcagga 5520 ctatgctgaa tctccttagg cattctctaa tcagatatcc tgagtcatcc caattcttag 5580 accttttata cctgtttttc tccttctgtt attccattta gtttctcaat tcatccaaaa 5640 ccatatccag gccatcacca atcattctat acgacaaatg tttcttctaa caaccccaca 5700 atatcacccc ttaccacaag acctcccttc agcttaatct ctcccactct aggttcccac 5760 gccgccccaa tcccgcttga agcagccctg agaaacatcg cccattctct ctccatatca 5820 ccccccaaaa attttcaccg ccccaacact tcaacaccat tttgttttat ttttcttatt 5880 aatataagaa ggcaggaatg tcaggcctct gagcccaagc caagccatcg catcccctgt 5940 gacttgcatg tatatgccca gatggcctga agtaactgaa aaatcacaaa agaagtgaat 6000 atgccctgcc ccaccttaac tgatgacatt ccaccacaaa agaagtgtaa atggcctgtc 6060 cttgctttaa gtgatgacat taccttgtga aagtcatttt cctggctcat cctggctcaa 6120 aaagcacccc cactgagcac cttgcgaccc ccactcttgc ccgccagaga acaaaccccc 6180 tttgactgga attttccttt atctacccaa atcctataaa acggccccac ccttatctcc 6240 cttcactgac tctcttttca gactcagccc acctgcaccc aggtgaaata aacagccatg 6300 ttgctcacac aaagcctgtt tggtggtctc ttcacacgga tgtgcatgaa a 6351 <210> 234 <211> 668 <212> DNA <213> Homo sapiens <400> 234 ttatagaaag tagtcaggca gacatgggca gagcaggaga gggcccaccc ccaaccccat 60 cagaaatgtc aggtgaccat caggtgatag gttaagctgt ctctctaaaa taataattgg 120 tcacagctgg caccagggaa aggcagtcac ccaacagaaa ctggtgatca gcagcttcct 180 ggtaagatct caggaggtgg gtgagtgggc tcaagcatgt gcactaagag gcaaaatggt 240 ggagtttaat tggtatatga ccttcttcca tgaacactgg gctggtaagg gaaaaatgcc 300 tcaagtgagc atgagtacaa tttcagtaaa cacactgtgt atgtggcccc tcccaagtgc 360 tggcaggtca ctgcacatgt gacagccacc tcaaaggatg aattgggaga agtaacacaa 420 ccctggaagc atgccaatgt ataagactcc aagtcaaagg tcaaaccatg cacttgatct 480 cttaggttgc ccgcctggcc ttcttccaag tgtactttac ttcctttcat tcttgctcta 540 aagcttttaa ataaactttc acttctgatc taaaacttgg ttcagtctct ccctctgcct 600 tatgcccctc agttgaattc tttcttctga gggggcaaga attgaggttg ctgcaaactc 660 ggatttgc 668 <210> 235 <211> 212 <212> DNA <213> Homo sapiens <400> 235 cccccagtca cataccccct gcttgctcaa tcaatcatga ccctctcatg gccaccccct 60 tagagttgtg agcccttaaa agggacagga attgctcact tggggagctc ggctcttgag 120 acaggagtct tgctgatgcc cccggccaaa taaacccctt ccttctttaa ctaggtgtct 180 gaggagtttt gtctatggct tgtcctgcta ca 212 <210> 236 <211> 386 <212> DNA <213> Homo sapiens <400> 236 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac gtacacatcc 60 aggtggctgg ttcctgcctt aactgatgac attccatcac aaaagaaatg aaaatggcct 120 gttcctgcct taactgatgg cattatcttg tgaaattcct tctcctggct catcctgtct 180 caaaagctcc cctgctgagc accccactcc tgcctgccag agaacaaccc tcctttttcc 240 tttacctacc caaatcctat aaaacggccc cacccctatc tcccttcact tttcggactc 300 agcccacctg cacccaggtg aaataaacag ctttattgct cgcacaaagc ctgtttggtg 360 gtctcttcac acggacgcga gtgaaa 386 <210> 237 <211> 435 <212> DNA <213> Homo sapiens <400> 237 gtcaggcctc tgagccgaag ccaagccatc agactccctg tgacctgcac gtatacatcc 60 agatggcctg aagcaactga agaacaacaa gaagaagcga aaatagctag ttcctgcctt 120 aactgatgac attccaccat tgtgatttgt tcctgcccca acctaactga tcaattgacc 180 ttgtgacatt ccttctcctg gacaatgaat ctcaggagct ccccactgag caccttgtga 240 tccccgcccc tgcccgcaag agaacaacct cctttaactg taattttcca ctatctaccc 300 aaatcctata aaactgcccg acccctatct ccctttgctg actccttttc tgaactcagt 360 ctgcctgcac ccaggtgatt aaaagcttta ttgctcatac aaagcctgtt tggtggtctc 420 ttcacatgga cgcac 435 <210> 238 <211> 447 <212> DNA <213> Homo sapiens <400> 238 gtcaggcctc tgagcccaag ccaagccatt gcatcccctg tgacttgcac gtatacgccc 60 agatggccta aagcaactga agaatcacaa aagaagtgaa tatgccctgc cccaccttaa 120 ctgatgacat tccaccacaa aagaagtgta aatggccggt ccttgcctta actgatgaca 180 ttaccttgtg aaagtccttt tcctggctca tcctggctca aaaccacccc aactgagcac 240 cttgtgaccc ccactcctgc ccgccagaga acaaaccccc tttgactgta attttccttt 300 acctacccaa atcctataaa atggccccac ccttatctcc cttcactgac tctcttttcg 360 gactcagccc acctgcaccc aggtgaaata gccatgttgc tcacacaaag cctatttggt 420 ggtctcttca cacggacgag catgaaa 447 <210> 239 <211> 714 <212> DNA <213> Homo sapiens <400> 239 ttacagtagg tagctagtca gacatgagca gggcaggaga gtgccaaacc ccaccaggaa 60 tgtcaggcaa ccatcaagtg tggtcaggtg gcgttaagct gtctctctaa aataataatt 120 ggtcacagcc agtgccagag aaaagcagtc tcccgataga tggaaaaaaa cctgaaactg 180 gtgatcagca tcttcccaat aagatttcaa gatttggttg agtgggctca agcatgtaca 240 ctaagaggca aaatggtgga gtttaactgg tgtgcgacct tctaggaaca ttgaactggt 300 aagggaagaa cgcctcaagt gagcatgcgt gcaactccag taaacacgct gcacatgcag 360 ctccttccaa gggctggcag gccactgtgc atgcagagag cccaccctaa gggaagaatc 420 aggagaggag agatgcaaac tctggaagca tgccaacatt taaagcccca agtcaaaggt 480 caaactgcgc acttgatctc tcaagtcgcc tgcttggctc tcttccaagt gtactttact 540 cccttttgtt cctgctctaa agctttttaa taaactttca ctcctgctct aaaacttgcc 600 ttggtctctc actctgccct gtgcccctcg gttgaattct ttcttgtgag gaagcaagaa 660 ctgaggttgc tgcagacccg tatggattcg ccgctgctaa cataatttgg tacc 714 <210> 240 <211> 6860 <212> DNA <213> Homo sapiens <400> 240 caggcctctg agcccaagct aagccatcat atcccctgtg acctgcacgt atacatccag 60 atggcctgaa gcaactgaag atccacaaaa gaagtgaaaa tagccttaac tgatgacatt 120 ccaccattgt aatttgtttc tgccccaccc taactgatca atgtactttg taatcgcccc 180 aacccttaag aaggttcttt gcaattctcc ctatccttga gaatgtactt cgtgagatcc 240 accccctgcc tgcaaaaaat tgctcctaac tccaccgcct atcccaaaac ctataagaac 300 taatgataat ccaccaccct ttgctgactc tctttttgga ctcagcccac ctgcacccag 360 gtaatataaa cagccttgtt gctcacacaa agcctgtttg gtggtctctt cacacggaca 420 tatgagacat ttggtgccaa agaccccggt cagcgggact ccttcaggag accagtcccc 480 tgttcttgcc ctcactccat gaagagatcc acctacgacc tcgggtcctc agaccaacca 540 gcccaaggaa catctcaccg attttaaatc gggtaagtgg cctcttttta ctctcttctc 600 caatctctct cactatccct caacctcttt ctcctttaaa tcttggtgcc acccttcaat 660 ctgtcccttc tcataatttc aattcctttc attttctggt agagacaaag gagacacatt 720 ttatccgtgg acccaaaact ccggcgcagg tcacagactc gggaaggcag ccttccctta 780 gtgtttaatc attgcaggtc gcctgcctga ttattcaccc acgtttcaga ggtgtctgac 840 ctcacgggga cacctgcctt ggtccttcac ccttagcggc aagcaccact tttctggggg 900 gcaagcaccc cttgacacct tctctccatg tctccacccc ttctccactt tcctgggggg 960 caagcactcc ccaccccttc tctccgtgtc tctactctct cttttctctc cacttttctg 1020 ggggacaagc accccccacc ccttctctcc atttctctac tctctctttt ctctccactt 1080 tcctgggagg caagcacccc ccactccttc tctccatgcc tctactctct cttttctctc 1140 cacttttctg gggaacaagc accccccacc ccttctctcc gtgcctctac tgtcttttct 1200 ctccactttt ctggggggca agcagccccc acctcttctg tctgtgtctc tatcccttct 1260 ccactttcct ggggggcaag cacctcccac cccgttccca ctttcctggg ggacaagcac 1320 ctcccacccc attcccactt tcctgggggg caagcacctc ccaccccgtt cccactttcc 1380 tggggggcaa gcacctccca ccccattccc actttcctgg gggacaagca cctcccaacc 1440 cgttcctact ttcctggggg gcaagcacct cccaccccgt tcccactttc ctgggggaca 1500 agcacctccc aacccgttcc tactttcctg gggggcaagc acctcccacc ccgttcccac 1560 tttcctgggg acaagcacct cccaccctgt tcccactttc ctggggggca agcacctccc 1620 acctcattcc cactttcctg ggagataagc acctcccacc ccgtttcaac tttcctgggg 1680 ggcaagcacc tcccacccct tctccacttt cctggggggc aagcaccccc taccccttct 1740 ctccatgtct ctacccttct ctttaaactt gcctccttca ctatgggcaa ccttctaccc 1800 tccattcctc cttctccctt agcctgtgtc ctcaagaact taaaacctct tcaactctcg 1860 cctgacctaa aacttaaacg ccttattttc ttctgcaata ctgcttgacc ccaatacaag 1920 ctcgacaatg gttctaaatg gccagaaaac ggcacttatg atttctccat cctatgagat 1980 ctagacaatt tttgtcaaaa aatgggcaaa tggtctgagg tgcctgacgt ccaggcattc 2040 ttttacacat tggttcctcc ctagtctctg ctcccagtga gactcgtccc aaatctttct 2100 tctttctctc ctgtctgttc cttcagtctc caccccaagc tcttgagtcc tttgaatcct 2160 tcttttctac ggactcatct gacctctccc cttctcccca ggctgctcct cgccaggcca 2220 agccaggtcc caattcttcc tcagcctctg cttccgcacc ctataatcct tctatcacct 2280 cccctcctca cacccagtct ggtttacagt tttgttccgt gactagtcct cccccacttg 2340 cccaactatt tcctcttaaa gacgtggctg gagctgaagg catagtcaac gttaatgctc 2400 ctttttcctc tatcagacct ttcccaaatc agccagcgtt taggctcttt ctcatcagac 2460 cccactaaat atatacagga attccgatat ctaactctgt cctacaattt aacctggagt 2520 gacttaaatg tcatcctgac ttctaccctc tccccggatg aatgggaaag agttttttct 2580 ccagcccaat ctcacactga taaccactgg cttcatgagc cagacctcca ggaaggcatt 2640 agagcagttc cccgagaaga tcccaatgga actatcaggc agattcccca ggtatagcta 2700 ggcgagatta catggtttcc tgcctagtta aagggcttaa aaaggcagct tacaaagctg 2760 ttatgacaaa cttaaagaaa ctacccgagg taaagacgaa agcccagccc agttcatggc 2820 cctcttagca gcaaccctga gacactttac tgccctagac ccagaggggc cagaaggccg 2880 tcttaatctc aatatgcatt ttattttatt aaccaatttg ctcccaacat taaataaagc 2940 tccaaaaatt aaattcggcc ctcgaacccc acaacaggac ttaattaacc tcgcttcaag 3000 gtgtacaata atagagtaga ggcagccaag tagcaatgta tttctgagtt gcaattcctt 3060 gcctccactg tgagacaaac cccagccaca tctccagcac acaagaactc caaacacctg 3120 aaccgccact gccaggggtt cctccagaaa ctccttcccc aggagcttgc tacaagtgct 3180 ggaaatctgg ccactgggcc aagcaatgcc cgcagcctgg gactcctcct aagccatgtc 3240 ccatctgtgc gggaccccag tggaaatcgg actgtccaac tcacctggca gccactcccg 3300 gagcccctgg aactctggcc caaggctctc tgactgactc attcccagat attctcagct 3360 tagtggctaa agactgacgc tgcctgatca cctcggaagc cccctggacc atcacagacc 3420 ctttgggtaa ctcttacagt ggagggtaag tccgtctcct tcttaatcaa taaggaggct 3480 accaactcca cattaccttc ttttcaaagg cctgtttccc ttgcctccat aactgttgtt 3540 ggtattgacg gccaggcttc taaacctctt aaaactcccc aactctggtg ccaacttgga 3600 caatattctt ttatgcactc attttagtta tccccacctg cccagctctc ttattaggtc 3660 gagacatttt aactaaatta tctgcttccc tgactattcc taggctacaa gcacacctca 3720 ttgccaccct tttccccagt tcaaagcctc ctttgcatcc tcctctcgta tccccctacc 3780 ttaacccaca agtatgggat acctctactc cctccttggt gacaaatgat gcacccctta 3840 ccatcccatt aaaacctaat cacccttacc ccactcaatg ccaatatccc atcccacagc 3900 atgctttaaa aggattaaag cctgttatca cttgcctgtt acagcatggc cttttaaagc 3960 ctgtaaactc tccctacaat tcccccattt tacctgtcct aaaacaagac aagccttacc 4020 ttagttcagg atctgcgcct tatcaaccaa attgtcttgc ctatccaccc catggtgcca 4080 aacccatata ctctcctatc ctcaatacca ccctccacaa cccctccata accccttatt 4140 ctgttctgga tctcaaacat gctttcttta ctattccttg cacccttcat cctagactct 4200 ctttgctttc acttggactg accctgacac ccattagact cacaaattac ctgggctgta 4260 ctgccacaag gcttcacgga cagcccccat tacttcagtc aagcccaaat ttcttcctca 4320 tccattacct atctcgacat aattcttcat gaaaatacac atgctctccc tgctgatcac 4380 gtctgactaa tctcccaaac cccaatgcct tctacaaaac aacaactcct ttccttcctg 4440 ggcatggttg gatacttttg cctttggata ctggttttgc catcctaaca aaaccattat 4500 ataaactcac aaaaggaaac ctagctgacc ccacagatcc taaatccttt tgccactcct 4560 ttccgttcct taaaaacagc cctagaagct gcccccacac tagctctccc taactcatcc 4620 caatcctttt tcattacaca cagccaaagt gcagggctgt gcagtcggaa tttttacaca 4680 agagctggga ctgcgccctg tagccttttt atccaaacaa cttgacctta ctgttttagc 4740 ctagccttca tgtctgtgtg cagtggctgc cgctgcctta atacttttag aggccctcaa 4800 aatcacaaac tgtgctcaac tcactctcta tagttctcat aacttccaaa atctattttc 4860 ttcctcacac ctgacgcata taatttctgc ccccctccac tacctctcag caagccaaac 4920 tcattgtctt aactcaagcc ctcactcttg caaagggact acgcgtcaat atttatactg 4980 actgtaaata tgccttccat atcctgcacc accatgctgt tataagggct gaaagaggtt 5040 tcctcactat gcaagggtcc tccatcatta atgcctcttt aataaaaact cttctcaagg 5100 ccgctttact tccaaaggaa gctgaagtca ttcactgcaa aggccatcaa aaggcataag 5160 atgccatcac tcagggcaat gcttatgctg acaaggtagc taaaaaagca gctagagttc 5220 caacttctaa ccctcatggc agtttttctc cttctcatct ggtcattctc acctattccc 5280 ccactgaaac ttccacctat caatctcttc ccacacaagg caaatggttc ttggaccaag 5340 gaaaatatct ccttccagcc tcacaagccc attctagtct atcgtcattt cataacctct 5400 tccatgtagg ttacaagcag ctagcccgcc tcttagaact tctcatttcc tttccatcat 5460 ggaaatctgt ccttaaggaa atcacttctc agtgttccat ctgctattct actactactc 5520 ctcagggatt gttcaggctg cctcccttcc ctacacatca agctcgggga tttgcccccg 5580 cccaggactg gcaaattgac tttactcaca tgcctcaaat caggaaacta aaatacctct 5640 tggtctgggt agacactttc actgggtggg tagaggcctt tcccacaggg tctgagaagg 5700 ccaccgtggt aatttcttcc cttctgtcaa acataattcc ttggtttggc cttcccactt 5760 ctatacagtc caataacaga ccggccttta ttagtcaaat cacccaagca gtttctcagg 5820 ctcttggtat ttagtggctc caggttttac ctcaaactgc cacccttaag tctctcttta 5880 agtggataga agttcttcag tgacaaagta cactccaata ctttcaccct gatgaagtcc 5940 tattctttac ttttatactt gctcttattc ttgtccccat ttttatgcca ctctctacct 6000 ctccccagct atctccacca cactatatca gtctcagtca ctctctccta gccatttcta 6060 atccttcttt aacaaacaat tgctggcttt gcttttctct ttcctccaaa attcccgagg 6120 ccctgactaa aaaaggggta ctcttgtata tttttaaatg aagaaaaaaa ggggactctg 6180 tatattttta aatgaagagt gttgttttta cctaaatcaa tctggcctgg tatatgacaa 6240 cataaaaaaa ctcaaggata gcacccaaaa actcaacaac caagcaaata attatgctga 6300 actcccttgg acactctgta attggatgtc ctgggtactc ccaattctta gtcctttaat 6360 atctgttttt ctccttctct tatttggacc ttgtgtcttt catttagttt ctcaattcat 6420 acaaaaccgc atccaggcca tcaccaatca ttctatacga caaatgtttc ttctaacaac 6480 cccacaatat caccccttac cacaaaatct tccttcagct taatctcacc cactctaggt 6540 tcccacgtca cccctaatcc tgctcgaagc agccctgaga aacatcaccc attatctctc 6600 cataccaccc ccaaaaactt tcgccacccc aacacttcac cactattttg ttttattttt 6660 cttattaata taagaagaca ggaatgtcag gcctctgagc ccaagctaag ccatcatatc 6720 ccatgtgacc tgcacatata catccagatg gcctgaagta actgaagatc cacaaaagaa 6780 gtgaaaatag ccttaactca tgacattcca ccattgtaat ttgtttctgt cccaccctaa 6840 ctgatcaatg tactttgtaa 6860 <210> 241 <211> 974 <212> DNA <213> Homo sapiens <400> 241 gtggggaaga gagagatcag tgtctctttc tatacggact gtgtctatat agaaagaagt 60 agacatgaga gactccattt tgttctgtac taagaaaaat tcttctgcct tgagatgctg 120 ttaatctgta accctacccc aaccctgtgc tcgcagaaac atgccctgtg tcgactcaag 180 gtttaatgga tttagggcta tgcaggatgt gctttgttaa acaaatgctt gaaggcagct 240 agcttgttaa aagtcatcac cactccctaa tctcaagtac ccagggacac aaaacactgc 300 ggaaggaagg ccgcagggac ctctgcctag gaaagccagg tttctcccca tgtgatagtc 360 tgaaatatgg cctcatggga agggaaaaga cctgaccgtc ccccagcccg acacccgtaa 420 agggtctgtg ctgaggagga ttagtaaaag aggaaggcct ctttgcagtt gagataagag 480 gaaggcgtct gtctcctgct catccctgag caatggaatg tctcggtgta aaacccgatt 540 gtatattcca tctactgaga taggagaaaa ccgccttagg gctggaggtg agacatgctg 600 gcggtaacac tgctttttaa tgcaccgaga tgtttatgta tgtgcacatc aaagcacagc 660 accttttcct taacattgtt tatgacacag agacatttgt tcacattttc ctgctggccc 720 tctccccact attaccctat tgtcctgcca catccccctc tgggagatgg tagagatggt 780 agagataatg atcaataaat actgagggaa ctcggagact ggggccagcg tgggtcctct 840 gtatgctgag cgccagtccc ctgggcccat ttttctttct ctgtactttg tctctgtgtc 900 tctttctttt ctcagtctct catcccaccc cacgagaaac acccacaggt gtggaggggc 960 aggccacccc ttca 974 <210> 242 <211> 769 <212> DNA <213> Homo sapiens <400> 242 gagagacagg actagctgga tttcctaggc cgactaagaa ttcctaagcc tagctgggga 60 aggtgaccgc acccgctttt aaacacaggg cttgtaactc agctcacacc tgaccaatca 120 ggaagtaaag acagctcact aaaataccaa ttaggctaaa agcaggaggt aaagaaatac 180 tcaatcatct atcgcctgag agcacaggga gagacaatga ccgggatata aacccaggca 240 ttggatccgg tgtggcaacc ccctttgggt cccctcccct tgtatgggag ctctgttttc 300 actctattat atcttgcaac tgcgcgctct tctggtccgt gtttgttctg gctcgagctg 360 agctttcact caccgtccgc cactgctgat tgctgccgtc gcagacccgc cactgacttc 420 caccctccag atccagcccg gtgcctgctg tgctcctgat ccagcgaggc gcccgttgcc 480 gctcccggtc gggctagagg ctcgccattg ttgctgcgcg gctaagtgcc caggttcatc 540 ctaattgagc tgaacgctag tcgctgggtt ccacggttct cttctgtgac ccacggcttc 600 taatagagct ataacaactc acctcatggc ccaacgttcc attccctgga atccgtgagg 660 ccaagaaccc caggtcaggg aacaaaaggc ttgtgccatc ttgggagcgg cccccccacc 720 atcttgggag ctctaagaac aaagacctgc tggtaacaca attttggta 769 <210> 243 <211> 5827 <212> DNA <213> Homo sapiens <400> 243 gtcaggcctc tggtcccaag cctgcacata tacatccaga tggcctgaag taactgaaga 60 atgacaaaag aagtgaaaat ggtcggttcc tgccttaact gatgacatta ccttgtgaaa 120 taccttctcc tggctcatcc tggctcaaaa gctcccccac tgagcacctt gtgaccccca 180 cacctgccag ccagagaata actccctttt actatacttt tccactacct acccaaatcc 240 tataaaacgg tctcacccct atctcccttt gctgactctc ttttcagact cagcccgcct 300 gcacccaggt gattaaaaag gtttattgct cacacaaagc ctgtttggtg atctcttcac 360 acggatgcag gtgaaatttg gtgtcatgac tcggatcagg ggacctccct tgggagatca 420 ataccctgtc ctcctgctct ttgctccatg agaaaggtgc acctacaaca tcgggtcctc 480 agaccaacca gcccaaggaa catctcacca attttaaatc atgtaagcgg cctcttttta 540 ctctcttctc caacctctct cactatccct caaccccttt ctcctttcaa tcttggtgcc 600 atccttcaat ctctcccttc tcttaatttc aattcttttc cttttctggt agagacagag 660 gagatgtgtt ttatccacga ccccaaaact ccggtgctgg tcatgaactc aggaaaacag 720 tcttcccttg gtgtttaatc actgcaagga tggctgcttg attattcacc cacgtttcag 780 aggtgtctga tcaccgcggg gatgcctgcc ttgatccttc acccttagcg gcaagcactg 840 cttttctggg ggcaagcagc ccccaccctt tctctccgtg tctctacccc ttttccactt 900 ccctgggagg caagcacctc ccacccttct ccactttcct tgggggcaag caccccccac 960 cccttctctc catgtcctct cttttctctg ggcttgcctc cttcactatg ggcaaacttc 1020 caccctccat tcctccctct tctcccttag cctgtgttct caaaaactta aaacctcttc 1080 aactcacacc tgacctaaaa cctaaatgcc ttattttctt ctgcaacacc gcttggcccc 1140 aatacaaact tgataatggc tctaaatggc cagaaaactg cattttcagt ttctccatcc 1200 tacaagacct agataatttt tgtcaaaaaa tgggcaaatg gtctgaggtg ccttacatcc 1260 agacattttt cacacttcgt tccctcccta gtctctgttc ccaatgcaat tcctcccaaa 1320 tcatccttgt ttccctcccg cctgtcccct cagtcccaac ctcaagcatc gctgagtctt 1380 tccaatcttc cttttctaca gacccatctg acctctctcc tcctccccag gctgctcctc 1440 accaggccaa gccaggtccc agttcttcct cagcctctgc tcctccaccc tataatcttt 1500 ctatcacctc ccctccttac acctggtctg gcttacggtt tagttctgtg actagctctc 1560 cccaacctgc ccaacaattt cctcttagag aggtggctgg agctgaaggc atagtcaggg 1620 tacatgtgcc tttttctcta tcggacctct ctcagatcag tcagcgttta ggatctttct 1680 catcaggccc tactaaatat atacatgaat tccaatatct aactctgtcc tacaatttaa 1740 cctggagtga cttaaatgtc atcctaactt ttatcctccc actagatgaa tgggaaagag 1800 ttttttctct ggcccaatct cacactgaca actgtcggct ccacaagcca gacctccagg 1860 aaggcattag agaagttccc caagaggatc cccaatggaa ctatcaggaa aattccccag 1920 gtatagctag gcgagattac atgatttcct gcctagttga agggcttaaa aaggcagctt 1980 acaaagctat taattatgac aagcttaaag aaactaccca aggtacagac aaaaacccag 2040 cccagtccat ggcttgtttg gcagcaacca tgagacactt tgcagcccta gaccctgaag 2100 gtcagaaggc tgtctcattc taaatatgca ttttatcacc cagtcagctc ctgacattag 2160 aaaagaactt caaaaattag aatccggccc tcaaacccca caataggaat taatcaacct 2220 cgccttcaag atgtacagta atagagagga gacaggcaga tggcaacgca tttctgagtt 2280 acaattactt gcctctgctg tgagacaaaa cccagccgca cctccagcac acaagaactt 2340 caaaatgcct aagctgcaca tgcctaagcc acagcagtca agcattccta caggacttcc 2400 tccatcagga tcttgcttca agtgccagaa atctggccac tgggccaagg aatgcctgca 2460 gcctgggatt cctcccaagc tgtgtcccat ctgtgcaggg acccactgga aatcagactg 2520 cccagctcac ccagcagcca ctcctagagc tgctaaagct ctaggccaag gctctctgac 2580 tgactccttc ccagatctgc tcagcttagc ggctgaagac tgacgctgcc caatcacctc 2640 agaaaccccc tggaccaaca cggactccga gtttcgggta attctcacag tggactgacc 2700 ctgacaccca tcagtcccag aagcttacct gggctgtgct gcctcaaggc ttcagggaca 2760 gccctcatta cttcagccaa gctctttctc atcatttact ttctttccac ccctccactt 2820 ctcaccttat tcaatatatt gatgaccttc tactttgtag cccctccatt gaatcttccc 2880 aacaagacac cctcctgctc cttcaacatt tattctccaa agggtatcgg gtatccccca 2940 ccaaagctca aatttcttct ccatccgtta cctacctcag cataattctt cataaaaaca 3000 cacatgctct ccctactgat cacgtccaac tgatctctca aaccccaacc ctttctacaa 3060 aacaactcct ttccttccta ggcatggttg gatactttca cctttggata cctggttttg 3120 ccatcctaac aaaaccatta tataaactca caaaaggaaa cctagctgac cccatagatc 3180 ctaaatcttt tccccactcc tctttccgtt ccttgaagac agctttagag actgctccca 3240 cactagctct ccctgactca tcccaatcct tttcattaca cacagccgca gtgcagggct 3300 gtgcagctgg aattcttaca caaggaccgg gactgtaccc tgtagccttt ttatccaaac 3360 aacttgacct tactgtttta ggctggccat catgtctccg tgcagcggct gccaccgccc 3420 taatactttt agaagacccc aaaatcacaa actatgctca actcactctc tacagctctc 3480 ataacttcca aaatctattt tcttcctcac acctgacaca tatactttct gctccccagc 3540 tccttcagct atactcactc tttgttgagt ctcccacaat taccattgtt cctggcccag 3600 acttcaatcc agcctcccac attattccag ataccacacc tgacccccat gactgtatct 3660 ctctgatcca cctgactttc accccatttc cccatatttc cttctttcct gttcctcacc 3720 ctgatcacat ttggtttatt gatggcagct ccaccaggcc taatcagcac tcaccagcaa 3780 aggcaggcta tgctatagta tcttccatgt ctatcattga ggctaccact ctgcctccct 3840 ccactacctc tcagcaagct gaactcattg ccttaacttg ggtcctcact cttgcaaagg 3900 gactacacat caatatttat actgactcta aatacacctt ccatatcctg cactaccatg 3960 ctgttatatg ggcagaaaga ggtttcctca ctatacaagt gtcctccatc attaatgcct 4020 ctttaataaa aactcttctc aaggctgctt tacttccaaa gaaaggtgga gtcattcact 4080 gcaagggcca ccaaaaggca tcagatccca ttgctctagg caatgcttat gttaataagg 4140 tagctaaaga agtagctagc attccaactt ctgtccctca tggccagttt ttctccttct 4200 catcggtcac tcccacctac tcccccactg aaacttccac ctatcaatct cttcccacac 4260 aaggcaaata tcttagacca aggaaaatat ctccttccag cctcacaggc ccattctatt 4320 ctgtcatgat ttcataacct cttccatgtt ggttacaagc tgctagcccg tctcttagaa 4380 cctctcattt tctttccatc atggaaatct gtcctcaagg aaatcacttc tcagtgttcc 4440 atccgctagt ctactgtccc tcaggtattg ttcaggcccc ctcccttccg tacacatcaa 4500 gcttggggat ttgcccctgc tcaggactgg caaattgact ttactcacat gtcctgagtc 4560 aggaaactaa aatacctctt ggtctgggta gacactttca ctggatgggt agaggccttt 4620 cccacagggt ctgagaaggc caccgtggtc atttcatccc ttctgtcaga cataattcct 4680 cagtttggcc ttcccacctc tgtacagtct ggtaacggac cggcctttac tagtcaaatt 4740 acccaagcag tttctcaggc tcttggtatt cagtggaacc ttcatacccc ttaccatcct 4800 caatcttcag gaaaagtaaa acagactaat ggtcttttaa aaacacatct caccaagctc 4860 agcctccaac ttaaaaagga ctggacaata cttttaccac ttgcccttct cagaattcgg 4920 gcctgtcttc aggatgctat aggttacagc ccatttgagc ttctgtatgg acactccttt 4980 ttattaggcc accagcccac ttgaactgca ccccaaaaac ttggatagag cctaaaaact 5040 caccaaccaa gcaagcaatt acgctaagcc ccctcggcac tctctaattg gatgtcctgg 5100 gtcctcccaa ttcttagtcc tttaatacct gtttttctcc ttctcttatt tggaccttgt 5160 gtcttccgtt tagtttctca attcatacaa aactgcattg aggccatcac caatcattct 5220 atatgacaaa tgctcctttt aacaacccca caatatcgcc tcttaccaca aaatcttcct 5280 tcagcttaat ctctcccact ctaggttccc atgctgcccc taatcccgct cgaagcagcc 5340 ctgagaaaca tcacccatta tctctccata ccactgccaa aacttttcac tgccccaaca 5400 ctttaccact atttcatttt atttttctta ttaatataag aagacaggaa tgtcaggcct 5460 ctgggcccaa gcctgcacgt atacatccag atggcctgaa gtaactgaag aatgacaaaa 5520 gaagtgaaaa tagccagttc ctgccttaac tgatgacatt accttgtgaa acatcttctc 5580 ctggctcatc ctggctcgaa agctcaccca ctgagcacct tgtgaccctg acccctgcta 5640 gccagagaac aacccccttt gactgtaatt ttccactacc tacccaaatc ctataaaatg 5700 gccccacccc tatctccctt tgctgactct cttttcggac tcagcctgcc tgcacccagg 5760 tgattaaaaa gctttattgc tcacgcaaag cctgtttggt ggtctcttca catggatgcg 5820 catgaaa 5827 <210> 244 <211> 652 <212> DNA <213> Homo sapiens <400> 244 ttacagtagg taggcagaca tgagcagcgt gggaggggtc ccccccacca cccccaacag 60 gaatatcagg cgaccatcag gagatgatgg tcaggcagtt cttaaatgtc tctctaaaat 120 aataattggt tgcagccagc gccagagaaa ggcagtctcc tagtagacag aaaacacctg 180 aaactggtga tcaacagctt cccgataagg tctcaggaac tgcgtgagtg ggctcgagca 240 tgtgcacgaa gaggtaaaat ggcagagttt aactggtata tgaccttcct ctaggagcac 300 tcgactggta aggaaagaat gcctttagtg agcatgcgca caactttagt aaacacactg 360 cacatgcggc ccctcccacg tgctggcagg ccagtgtgca ggcggacagc ccaccccagg 420 ggaagaatca ggggagaagt aacgcaaccc cagaagcaca ctcaatgtac taaaccccaa 480 gtcaaaggtc aaactatgta cttgatctct aaagtcaccc acttggccct ccaagtgtac 540 ttccttttgt tcctgctcta aagcttttta acaaactttc actcctgctc taaaacttgc 600 ctgggtctct cagtctgcct aatgcccctg ggtcaaattc tttcttctga gg 652 <210> 245 <211> 6489 <212> DNA <213> Homo sapiens <400> 245 gtcaggtctc tgagcccaag ataagccatc atatcccctg tgacctgcac atatacatcc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aatggcctgt tcctgcctta 120 actgatgaca ctaccttgtg aaattccttc tcccggctca tcctggctca aagtctcccc 180 cactgagcac cttgtgaccc ccacccctgc cagccagaga acaaccccct ttgacagtaa 240 ttttccacta cctacccaaa tcctataaaa cggccccacc ccatctccct tcactgactc 300 tcttttcgga tcagcctgcc tgcaccaagg tgaaataaac agccttgttg ctcacacaaa 360 gcctgtttgg tggtctcttc acacggacgt gagtgaaatt tggtgctgtg actcggatca 420 ggggacctcc ctcgggagat caatcctctg tcctcctgct ctttactcca tgagagagat 480 ccacctacga cctcgggtcc tcagaccaac cagcccaagg aacatctcac caattttaaa 540 tcgggtaagc ggcctctttt tattctcttc tcctccctct ctcactatcc ctcaacctct 600 ttctcctttc agtcttggtg ccatctttca atctctccct tctcttaatt tcagttcctt 660 tccttttctg gtagagacag gagatgcgtt ttatctgtga acccaaaact ccggcaccgg 720 tcacagactt gggaagacag tcttcccttg gtgtttaatc atgcagggat gcctgcttta 780 ttattcaccc atgtttcaga ggtgtctgat cacacgggga tgcctgcctt ggtccttcac 840 ccatagcagc aagcaccact tttctggggg caagcacccc ccaccccttc tctctgtgtc 900 tctacccctt ttccgctttt cttaggggca agcactcccc aatccttctc tccatgtctc 960 cactctctct tttctctggg cttgcctcct tcactacggg caacctacca ccctccattc 1020 ctccctcttc tcccttagcc tgtgttctca aaaacttaaa acctcctcaa ctcacacctg 1080 acctaaaacc taaatgcctt attttcttct gcaacaccgc ttggccccaa tacaaacttg 1140 acaatggctc taaatggcca gaaaacggca ctttcaattt caccatccta caagacctag 1200 ataatttttg tcgaaaaatg ggcaaatggt ctgagatgcc ttacatccag gcatttttca 1260 cacttcattc cctccctagt ctctgtaccc aatgcgattc ctcccaaatc ttccttcttt 1320 ccctcctgcc tgtcccctca gtcccaaccc caagtgtcgc tgagtctttc caatcttcct 1380 tttctacaga tcatccgacc tctcccctcc tccccaggct gctcatcgcc aggctgagcc 1440 aggtccaatt cttcctcagc ctccgctcct ccaccctata atccttcgat cacctcccat 1500 cctcacaccc agtctgtctt acagtttgga tccaagacta gctcttctcc agctgcccaa 1560 caatttcctc ttagagagtg gctggagctg aaggcacagt cagggtacat gtgccttttt 1620 ctctttcaga cctctctcag atcagtcagc actcagaccc tactgaatat atacaggaat 1680 tccaatatct aactctgtcc tacaatttaa cctggagtga cttaaatgtc atcctaactt 1740 ctaccctctc cccagattca caggaaattt tttctctggc ccaatctcac actgacaacc 1800 gctggctcca tgaaccagac ctccaggaag gcattagcgc agttccccga gaggatcccc 1860 aatggaacta tcaggcagat tccccaagta tagctaggtg agattacatg gtttcctgcc 1920 tagttgaagg atttaaaaag gcagcttaca aagctgttaa ttatgacaag cttaaagaaa 1980 ctacccaagg taaagacgaa aactcagccc agttcatggc tcatttggca gcaaccctga 2040 gatgctttac agccctagac cttgaaggcc caggctttct gactgtctca ttctaaatat 2100 gcattttatc acccagtcag ctcctgacat tagaaaaaaa cttcaaaaat tagaatccgg 2160 ccctcaaacc ccacaacagg aattaatcaa cctcaccttc aagttgtaca ataatagaga 2220 aaagttacaa ttacttgcct ccaccgtgag acaaaatccc agctacatct ccagcacaca 2280 agaacttcca aacacctaaa ccgcagcggc caggcattgc tccaggaccc cctccccaag 2340 gaacttgctt caagtgctgg aaatctggcc actgggccaa ggaatgccct cagcctggga 2400 ttcctcctaa gccgtgtccc atctgtgcgg gaccccactg gaaatcggac tttctaactc 2460 gcctggcagc cactcccaga gcccctggaa ctctggccca aggctctctg actgactcct 2520 tcccagatct tctcggctta gcggctgaag gctgacgctg cccaattgcc tcagaagctt 2580 cctggaccat cacagatgct ttgggtaact cttacagtgg aggttaagtc cgtccccttc 2640 ttcttcttct tttttttttt ttttgttttg agatgcagtc ttgctctgtc gcccaggctg 2700 gagtgcagtg gcacgatctc agctcactgc aagctccgcc tcccaggttc acgccactct 2760 cctgcctcag cctcctgagt agctgggact acaggcacct gcctctgcgc ccggctaatt 2820 ttttttgtat ttttagtaga gacggggttt cactgtggtc tcgatctcct gacctcgtga 2880 tccacccgcc tcagcctccc aaagtgctgg gattataggt gtgagccacc gcacccggcc 2940 ccttcccctt cttaataaat agggaggcta ccaactccac attaccttct tttcaaaggc 3000 ctgtttcctt tgcctccata actgttgcgg gtattgacag ccaagcttca aaacccctta 3060 aaactccccc actctggtgc caacttggac aacattcttt tatgaagtct tttttagtta 3120 tccccacctg cccagttcct tattaggcca agacatttta actaaattat ctgcttccct 3180 gactattcct aggctagagc cacacctcat tgccaccctt cttcccaacc caaagcctcc 3240 tttgcatctt cctctcgtat ccccccacct taacccacaa gtatgggaca cctccactcc 3300 ctccctggca accgatcaca tgcccattac tatcccatta aaacctaatc acccttaccc 3360 cgctcaatgc cagtatccca tcccacaata ggctttaaag ggattgaagc ctgttatcat 3420 tcgcctgtta caccatggcc ttttagagcc taaaatctct ccttacaatt cccccatttt 3480 acctgtccta aaaccagaaa agccttaccg gttagttcag gatctgcgcc ttatcaacca 3540 aattgtttta cctatccacc ccagggtgcc aaacccatat actctcctct atcctcaata 3600 cctccctcca caacccattc tgtcctagat aaacctagct gaccccataa atcctaaatc 3660 ctttccccac tcccctttcc attccttaaa aaacagccct aaaagctgct cccacactag 3720 ctctccctaa atcatcccaa ccttttcatt acacacagcc gaagtgcagg gctgtgtggt 3780 cagagttctt agacaagagc tgggactgca ccctgtagcc tttttatcca aacaacttga 3840 ccttactgtt ttagcctagc cctcatgtct gcatgtggcg gctgccgctg ccttaatact 3900 tttagaggcc ctcaaaatca caaactatgc tcaactcact ctctacagtt ctcataactt 3960 ccaaaatcta ttttcttcct cccacctgat gcatatactt tctactcccc agcttcttca 4020 gctatactca ctctttgttg aatctcccac aattaccatt gttccaggcc cggacttcaa 4080 tccggcctcc cacattattc cagataccac acctgacccc catgactata tctctctggt 4140 ccacctgacg ttcaccccat ttccccacat ttccttcttt actgtttctc accctgatca 4200 catttggttt attgatggca gctccaccag gcctaatcgc cactcaccgg caaaggcagg 4260 ctatgctata gtatcttcca cacctatcat tgaggctact gctctgcccc cctccattac 4320 ctctcaacaa gccaaactca ttgccttaac tcgagccctc gcccttgcaa aaggactatg 4380 tgtcaatatt tatactgact ctaaatatgc cttccatatt ctgcaccacc atgctgttat 4440 atgggcagaa agaaatttcc tcactatgca tgggtcctcc atcattaatg cctctttaat 4500 aaaaactctt ctcaaagcca ctttacttcc aaaggaagct ggagtcattc actgcaagag 4560 ccatcaaaag gcatcagatc ccatcgctca agacaatgct tatgctgata aggtagctaa 4620 aaaagcagct agctttccaa cttctatccc tcacggcagt ttttctcctt ctcatctggc 4680 cactcccacc tactccccca ctgaaacttc cacctatcaa tctcttccca cataaggcaa 4740 atggttcttg caccaaggaa aatatctcct cgcagcctca caggcccctt ctattctgtc 4800 atcatttcat aacctcttcc atgtaggtta caagctgcta gcccacctct tagaacctct 4860 catttccttt ccatcgtgga aatctatcct taaggaaatc acttctcagt gttccatctg 4920 ctattctact actcctcagg gatttttcag gcctccctcc attccctaca catcaagctc 4980 ggggatttgc ccctgcccag gactggcaaa ttgactttac tcacatgcct tgggtcagga 5040 aactaaaata cctctggtct gggtagacac tatcactgga taggtagagg catttcccac 5100 agggcctcag aaggccaccg tggtcatttc ttcccttttg tcagacataa ttcctcggtt 5160 tggccttccc acctctatac agtccaataa tgggccggcc tttattagtc aaatcaccca 5220 agcagtttct caggctgttg gtattcagtg aaaccttcac accccttacg gtcctcaatc 5280 ttcaggaaag gtagaatgga ctaatggtct tttaaaaaca cacctcacca agctcagcca 5340 ccaacttaaa aaggactgga caatactttt accacttgcc cttctcaaaa ttcgggcctg 5400 tccttggaat gctacagggt acagcccatt tgagctcctg tatggacact cctttttatt 5460 aggccccagt cttattccag acaccagccc aacttggact gcaccccaaa aacttgtcat 5520 ctctactatc ttctgtctag tcatactcct attcaccgta ctcaactact cataaatgcc 5580 ctactcttgt ttacactgct ggtttacact gtttctccag gccatcacag ctgatatctc 5640 ctggtgctat ccccaaacag ccactcttaa ctccctctta aagtaaataa ataatctttg 5700 ctggcagggc catgctgaac ctccttgggc actctctaat tggatggcct gggccctccc 5760 aattcttagt cctttaatat ctgtttttct ccttctctta tttggacctt gtgtcttcca 5820 tttagtctct caattcatac aaaacagcat ccaggccatc accaatcatt ctatatgaca 5880 aatgctcctt ttaacaaccc cacaatattg cccttaccac aaaatcttcc ttcagcttaa 5940 tctctcccac tctgggttcc cacgtcaccc ctaataccgc ttgaagcagc cccaagaaac 6000 attgcccatt atctctccat agcaccccca aaaattttcg ctgccccaac actttaccac 6060 tattttgttt tatttttctt attaatataa gaagacagga atgtcatgcc tctgagccca 6120 agctaagcca tcatatcccc tgtgacctgc aggtatacat ccagatggcc tgaagtaact 6180 gaagaatcac aaaagaagtg agaatggcct gttcctgcct taactgatga cactgccttg 6240 tgaaattcct tctggctcaa aatctccccc attgagcacc ttatgacccc cacccctacc 6300 agccagagaa caaccccctt tgactgtaat tttccattac ctacccaaat cctataaaat 6360 ggccccaccc ctatctccct tcactgactc tcttttcgga ctcagcccac ctgcacccag 6420 gtgaaataaa cagccttgtt gctcacacaa agcctgtttt gtggtctctt cacatggaca 6480 tgagtgaaa 6489 <210> 246 <211> 470 <212> DNA <213> Homo sapiens <400> 246 accttcaagc tccaaattat cctcagtgag gataccatct tctaaatact caggagtcac 60 ccttctatag aagaccacta ggctgcccat cagtagaaca caacaaagga aaaatcctgt 120 ttgtgtttcc cttggaccta cctggatagc actttcacca aaccacagag ccactctgcc 180 ctgacagtta tcaagaggcc aaaacccaca ggacaacttt caccacccct ctctcagtag 240 gaagcagtta tagacgcctg atctttgtcc attttcccca agaactgggt cttggagtat 300 tgagggggaa tgttagagta ggtagttagt cagacatgag cagggcatga aagtggctca 360 ttctccccag gaatatcagg tgaccatcag gtgatggtca agcagttgtt aacctgtctc 420 tctaaaataa ttggttgcaa cgggtgccag agaaaggcca tctcccaata 470 <210> 247 <211> 6565 <212> DNA <213> Homo sapiens <400> 247 agctgaaagt aaatatgcct cttatctcag cttcattaaa attatcttaa gaagaggggg 60 agttaaagct tctacagaaa atctaattat gctatttcaa acaatagaac aattctgccc 120 atggtttcca gaacagggaa ctttatattt aaaagattgg gaaaaaattg gcaaagaatt 180 aaaacaagca agtagggaag gtaaaatcat cccacttaca gtatggaatg actgggccat 240 tattaaagca actttagaac cgtttcaaat agaagaagat agtgtttcag tttctgatgc 300 ccctgagagc tgtgtaatag attgtgaaga agaggcagga acagagttca agaaaggaat 360 ggaaagttca cattgtaaaa atgtagcaga gtctgtaatg gctcggtcaa tgcaaaattg 420 ttgactataa tcaattacag gaggtaatat atcctgaatc atcaaaattg gcagaaggag 480 gtccagaatt atttgggtca tcagagttta aaccacgacg gccatcaact cctcctcctg 540 cggttcagat gcctgtgaca ttacaacctc aaatgcaggt tagacaagta caaactgcaa 600 gagaatatca agtagaaaag gatagagtct ctatcccggc aatgccaatc cagacacagt 660 atccacaata tcagctggta gaaaataaaa cccaaccact ggtagtttat caatactggc 720 cgccagtcaa atttcagtat cagctgcttc cagaggttca gtatagatct caggcggggt 780 gtcctgtccc aaatagcagg gcactatatc agcaacccac agcgatggcg tttgatccta 840 cagcaccagc tagtgtacaa gatagtacac tgcataaaac cattagccag aaaacaggga 900 gatcttgagg catggcagta cccggtaatt ttacaaccga tactggctgg gaaagggagt 960 caagcaggag cctctgtcca aactgagatt agatatgaat ctttcaccct gaaaatgtta 1020 aaagatatga aggaaggagt taaacaatat ggacccaact ctccttatat gagaacatta 1080 ttagattcca ttgctcatgg aaatagactt attccttatg attgggaaat tttggctaag 1140 tcttcccttt caccctctca gtttctacag tttaaaacct ggtggattga tggagtacaa 1200 gaacaggtaa ggaaaaatca ggctacttat cctgctgtta atatagatgc agaccaattg 1260 ctaggaacag gtccaaattg gagcactatt aaccaacaat cagtaatgca gaatgaggct 1320 attgaacaac taaggactat ttgcctcagg gcttgggaaa aaaattcagg acccaggaac 1380 ctcctgccat tcttttagtt caatcagaca aggctctaag agccatatcc agacttcgtg 1440 gcaaggttgc aagatgccgc tcaaaaatct attgcagatg ataacgcctg aaaagttgtt 1500 gtagaaataa tggcttatca aaatacaaat ccagaatgtc aatcagccat aaagccatta 1560 agagaaaatg ttccagcagg agttgatgta attacagaat atgtgaaggc ttgtgatggg 1620 attggaggag ctatgcataa ggcaatgcta ttggctcaag caattacggg ggttgcttta 1680 ggaggacaag ttagaacatt tggggggaaa tgttataatt gtggtcaaat tggtcatcta 1740 aaaaagaatt gcccagtctt aaataaacag agtaaaaata aagagccacc tggcctgtgt 1800 ccataatgtg aaagaggaaa acactgggct aaggaatgtc attctaaatt tgataaaaat 1860 gggcaaccat tatcgggaaa tgggaagagg ggccagcctc aggccccgcg acaaagtggg 1920 gcgttcccga ttcagccatt tgttcctcag ggttttcagg gacaacaacc cccacagcaa 1980 ataccaccat ttcagggaat cagccaatta caacaataca acagttctcc cccaccacag 2040 cgggcagcac agcagcagat ttatgttcta ctcaaagggt ttctttactc cctggatagc 2100 ccccgcaaaa gattcctaca ggggtatatg gtacactgcc agaagggatg gtaggcctta 2160 ttttaggaag atcaagtcta aatttgaagg gagtccaaat tcatactggg gtaattgatt 2220 cagattataa aggggtaatt cagttagtga ttaactccac tgttccctgg agtgccaatc 2280 caggtgatag aattgctcaa ttattgcttt gccttatatt aaaattgggg atagcaaaac 2340 agaaagaaca agagggtttg gaagtaccaa ccctgctgga aaatctgttt attggagtag 2400 tcagttctca gagaatagat ctgtgtgtac agtcactatt cagggaaagc agtttgaaag 2460 attagtggat actggggctg atgtttctat cattacctta aatcagtggc caaaaaattg 2520 gcctaaacaa aagtctgtta caggacttgt tggtgtgggc gccacctcag aagtgtatca 2580 aagtgccatg attttacatt gtctaggacc taataatcaa gagagtacag ttcagcctat 2640 gattacttct attccaatta atttatgggg ccgagacttg ttacaagagt ggcatgcaga 2700 gattactatt ccagtctccc tatacagccc cacaagtcaa aaaatcatga ctaaaatggg 2760 atatctccct ggcaaaggac taggaaagaa tggagaaggc attaaagtcc caattaaggc 2820 taaggaaaat ccagaaagaa aaggaataga gtatcctttt taggagtggc cactgtagag 2880 cctccaaaac ccattccatt aacttggaaa acagaaaagc ctgtatgggt aaatcagtgg 2940 ccactaccaa aacaaaagct ggaggcttta cacttattga caaaggaaca attagaaaag 3000 ggacataatg agccttcatt ttcgccttgg aattctcctg tgtttgtaat tcagaaaaaa 3060 tcaggcagat ggcgcatgct aactgactta agagctgtta atgcagtaat tcaacccatg 3120 gggcctctcc aacccgggct gccctctcta gccatgattc ccaaagattg gcctttaatt 3180 ataattgatc taaaggattg ccttttttac cattcctctg gcaaaacagg attttgaaaa 3240 atttgctttt actataccag ccataaatag taaagaacaa gccaccaggt ttcagtggaa 3300 agtgttgcct cagggaatgc ttaatagtcc aactatttgt cagacttttg tagctcaggt 3360 tcttcaacca gttagaaaca agttttcaga ctgttatatc attcattatg ttgatgatat 3420 tttgtgtgct acacaaatga gacaaattaa ttgactgtta cacatatgta gtacaggcta 3480 caaaggatgt tgagacagcc ctaatcaaat atagtatgga tgatcagtta aatcagctgt 3540 ttaatttgtt acaacaaact gtaagaaaaa gaaatttccc attttatatt actcatattc 3600 aagcacacac taatttacca gggcctttaa ctaaagcaaa tgaacaagct gacttgctac 3660 tatcatctgc gtttatggaa gcacaagaac ttcatgccct gactcatgta aatgcaacag 3720 gattaaaaaa taaatttgat atcacatgga aacagtcagt gtcgagtcct acacctaccc 3780 actcaggagg cgggaattaa tcccagagat ttatgtccta atgcattatg gcaaatggat 3840 gtcacacatg taccttcact tggaaaattg tcatttgtcc atgtgacagt tgatacttat 3900 tcacatttca tatgggcaac ctgccagaca ggagaaagta ctcctcatgt taaaagacat 3960 ttactatctt gttttgctgc catgggagtt ccagaaaaaa attaaaacag ataacgggcc 4020 aggatactgt agtaaagcat ttcaaaaatt cttaaataag tggaaaatta cacatacaac 4080 aggaatccct tataattccc aaggacaggc cataatagaa agaactaata gaacacttaa 4140 agctcaattg gttaaacaaa aaaaaaaaaa aaaaaaaaga aagtaaggag cataacactc 4200 cccagatgca acttaatcta gcactcttta aattttttag acatttataa aaataagacc 4260 actacttctg cagagcaaca ttttactggt aaaaaaaaca gcccatatga gggaaaactg 4320 atttggtgga aagacattaa aaataagaca tgggaaatag gtaaggtgat aacatggggg 4380 acaggttttg cttgtgtttc acaaggagaa aatcagcttc ctgtttggat acccactaaa 4440 catttaaagt tctacaatga acccatctga gatgcaaaga aaagtgcctc cacagagaca 4500 gaaaacctgc aatcgagcat cattgactcg ccaggtgaac aaaatggtga tatcggaaga 4560 acagatgaag ttgccatcca ccaagaaagc ggagcagccg acctgggccc aacaaaagaa 4620 gctgacacag ttaactgaaa aaagcctgaa aaacacaagg gtaacaaaaa ctccagagaa 4680 tatgctgctt ccagctttaa tgattgtatc aacagtggta agtctcccta tgtctgcagg 4740 agcagctgca gctaattata cttactgggc ctatgtgcct ttcccaccct taattccggc 4800 agtcacttgg atagataatc ctattgaagt atatgttaat aatagtgcat gagtaccagg 4860 ccccacagat gaccatggcc ctgtccaacc taaagaagaa gaaatgatga taaacatttc 4920 cattgggtat cattatcctc ctatttgcct ggggaaagca ccaggatgct taaggcctac 4980 aacccaaaaa ttggttggta gaagtaccta ctgtcagtgc caccagtaaa tttacttatt 5040 acatggtaag tggaatgtcg ctcgggtcac aaatgaataa tttacaggac tcttcttatc 5100 aaagatcatt aaaatttaag cctaaagaaa aaacttgccc caaggaaatt cccaaagaat 5160 caaaagaccc aaaagtctta gtttgggaag aatgtgtggc tgatactgcg gtggtattac 5220 aaaacaataa atttggaact attatagact gggccccttg aggacaatta tagtatgatt 5280 gtatgggcta gactcactca tattcacagg ctccatctgt ctggcccact aatccggcct 5340 atgatagtga tttgactgaa aggctagacc aggtttatat aaggttagaa tcaccctatc 5400 catggaaatg gggtgaaaag ggaatttcat caccccaacc aaagttagtt agtcttgtta 5460 ctggtcctga acactcaaaa ttatggaagc tcactgtggc ctcgcaccgc attagaattt 5520 ggtctggaaa tcaagttatg gaaacaagaa attgtaagcc atattatact atcgacctaa 5580 attccaatct gacaattcct ttgcaaagtt gtgtaaaacc cccttatatg ctagttgtgg 5640 gaaacatagt tattaaacca gattccaaaa ctataacctg tgaaaattgt agattgttta 5700 cttgtattga ttcaactttt gattggcagc accatattct gctagtgagg gcaaaagagg 5760 gtgtgtggat ccctgtgtcc acggaccgac catgggaggc ttccccatct gtccatattt 5820 taatagaagt attaaaagga gttctaacta gatccaaaag attcattttt acttcaattg 5880 cagtgattat ggatcttatt gcaatcacag ctactgctgt ggctgctgga attgctttac 5940 actgctctgt tcaagctgca aaatatgtaa ataattggca aaagaattcc tcaaaattgt 6000 gaaattctca gactcaaata gatcaaaaat tggcaagcca aattaatgat cttagacaac 6060 tgtcatttgg atgggagata ggctcatgag cctgaaatat ctttttcagt tacagtgtga 6120 ctggaataca tcagattttt gtattacacc tcgagcctat aataaatctg aacatcactg 6180 ggacacggtt agatgccatt tacaaaaaag agaagataat cttactttaa atatttcaaa 6240 attaaaagaa caaatttttg aggcatcaaa agcccagtta aatctggtgc cagaaactga 6300 ggcaatggta aaagctgttg atagcctcac aaatcttaac cctgtcactt gggttaaaac 6360 cactgaaaat tccactattg caaattttgt attaatcctt gtatgtctgt tctctctgtt 6420 gttagtctac aggtgtatcc agcagcttcg gagacacagc gaccggcgag aacgggacat 6480 gatgatgatg gcggttttgt caaaaagaaa agggggatat gtagggaaaa gaaagtgaga 6540 tcagactgtt actgtatcta tgtag 6565 <210> 248 <211> 451 <212> DNA <213> Homo sapiens <400> 248 gtcaggcctc tgaggccaag ccaagtcatc gcatcccctg tgacttgcgc gtatatgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa tatgccctgc cccgccttaa 120 ctgatgacat tccaccacaa aagaagtgta aatggccggt ccttgcctta agtgatgaca 180 ttaccttgtg aaagtccttt tcatggctca ccctggctca aaaacacccc cactgagcac 240 cttgcgaccc ccactcctgc ccgccagaga acaaaccccc tttgactgta attttccttt 300 acctgcccaa atcctataaa acggccccac ccttatctcc cttcactgac tctcttttca 360 gactcagcct gcctgcaccc aggtgaaata aacagccatg ttgctcacac aaagcctgtt 420 tggtggtctc ttcacacgga cacgcatgaa a 451 <210> 249 <211> 412 <212> DNA <213> Homo sapiens <400> 249 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac gtacacatcc 60 acatggccgg ttcctgcctt aactgatgac atttcaccac aaaagaagtg aaaatggcct 120 gttcctgcct taactgatga cattgtcttg tgaaattcct tctcctggct catcctggct 180 caaaagctcc cctactgagc accttgtgac ctccagtctg cccgccagag aacaaccccc 240 ctttgactgt aattttcctt tatccaccca aatcctataa aatggcccca cccctatctc 300 ccttcaatga ctctcttttc ggactcagcc cacctgcatc cagatgaaat aaacagcttt 360 attgctcaca caaaacctgt ttggtggtct cttcacacgg acaagcatga aa 412 <210> 250 <211> 7906 <212> DNA <213> Homo sapiens <400> 250 gtcaggcctt tgagcccaag ctaagccatc atacccctgt gacctacacg ttatacatcc 60 agatggcctg aagcaattga agatccacaa aataagtgaa aatagcctta acggatgaca 120 ttccaccatt gtgatttgtt tccaccccac cctaactgat acatatattc tcccccaccc 180 ttaagaaggt acttcggaat gttctctccc gctcttaaga atgtgctttg tatgcctatc 240 ccaaacctgt aagaactaat gataatccca ccaccctttg ctgactcttt tttttggact 300 cagcccatct gcactcaggt gaaataaaca gccttgttac tcacacaaag cctgtttggt 360 ggtctcttca catggatgtg cgtgacattt ggtgccgtga ctaggattgg gggccctccc 420 ttgggagatc aatcccctgt cctcctgctc tttgctccat gagaaagatc cacctacgac 480 tttgggtcct tagaccaacc agcccaagga acatctcacc aattttaaat cgggtaagca 540 gcctcttttt actctcttct ccagcctctc tcagtatccc tcaatctctt tctcctttca 600 atcttggcac catccttcat ttctcccttg tcttaatttc agttcatttc cttttctggt 660 agagacagag gagatgcgtt ttatccgtga acccaaaact ccggcactgg tcatggattc 720 aggaagacag tcttcccttg gtgtttaatc actggaggga tgcctgcttg attattcacc 780 cacgtttcag aggtgtctga tcacagtggg gatgcctgct ttgatccttc acccttagtg 840 gcaagcacca ctttcctggg gggcaagcac accccactcc ttctctttgt gtctctaccc 900 tctcttttct ctgggcttgc ctccttcact atgggcaaac ttccaccgtc cattcctcct 960 tcttctccct tagcctgtgt tctcaaaaac ttaaaacctc ttcaactcac acctgaccta 1020 aaacctaaat gccttatttt cttctgcaat gctgcttaac cccaatacaa actcgacagt 1080 ggttccaaat agccagaaag tggcactttt gatttttcca tccaacaaga tctagataat 1140 tcttgtcgta aaatgggcaa actgtctgag ctgcctgatg tccaggcatt cttttacaca 1200 tcagtccctc tctagtctct gttctcaatg tgactcgtcc caaatcctcc ttgtttccct 1260 cctgcctgtc ccctcagtcc caaccccaag catcactgtg tcttttcaat cttccttttc 1320 tacagaccca tctgacctct cccctcatcc ccagactgct ccacctcggg tcactccctg 1380 ccaggctgaa tcaggctcca attctttctc agcctccact ccccctaccc tataatcctt 1440 ctatcaactc ccctcctcac acccggtctg gcttacactt tcgttccacg actagccctc 1500 tcccacttgc ccaaaaattt cctcttaaag aggtggctgg agctaaaggc atagtcaggg 1560 ttaatgctcc tttttcttta tccgacctct cccaaatcaa ttggcattta ggctcttttt 1620 catcaaatat aaaaacccaa ctcagttcat ggctcgtttg gcagcatccc tgagatgctt 1680 tacagcccta gaccctgaaa ggtcagaagg ccgtcttatt ctcaacatgc attttattac 1740 ccaatccact cccgacatta aaaaagctcc aaaaattaga ttctggccct caagcccccc 1800 aacaggactt aattaacctc gccttcaagg tatacaataa tagagtagag tcagccaagt 1860 ggcaacatat ttctgagttg caattccttg cctccactgt gaaagaaacc ccagccacat 1920 ctccagcaca caagaacttc aaaatgcata caccgcagtg gtcaagcatt cctacaagac 1980 ctcttccatc aggattttac ttcaagtgcc agaaatctgg ccactgggcc aaggaatatc 2040 tgcagtccgg gattccttct aagccgtgtc ccatctgcac aggaccccac tgaaaatcag 2100 actgtccact gaaactcacc cggcagccac tcccagagcc cctagaactc tggcccaagg 2160 ctttctgact gactccctcc cagatcttct tggcttagtg actgaagact aatctcccaa 2220 tcacctcaga agcttcctgg accatcacag atgctttggg taactcttac agtggagggt 2280 aagtccgtcc ccttcttaat gtggagccta cccactccac attaccttct tttcaatggc 2340 ctgtttccct tgcccccaca actgttgtgg gtattgacgg ccaagcttca aaacccctta 2400 aaacttcccc actctggtac caacttggac aatattcttt tatgcactct tttttagtta 2460 tccccacctg cccagttcac ttattaggct gagacatttt aaccaattta tctgcttccc 2520 tgactattcc tggactacag ccacatctca ttgccaccct tcttcccaac ccaaagcctc 2580 ctttgcatct tcctctcata tccccctacc ttaacccaca aatatgggac aactctactc 2640 cctttcctgg caaccgatca catgcccatt actagcccat taaaacctaa tcacccttat 2700 cctgctcaat gccagtatcc catcccacaa caggctttaa ggggattgaa gcctgttatc 2760 actcacctgc cactgcatgt acttctaaaa cttataaact ctccttacaa ttctcccatt 2820 ttacgtgtcc aaaaactgga caagtcctac aggttagttc aggatctgca ccttatcaac 2880 caaattgttt tgcctatcca ccctgtggtg ctcaacccat acaccctttt gttctcaata 2940 ccttcctcca caactcacta ttccgttctt gatcttaaag atgctttttt cactattccc 3000 ctgcacccct tgtcccagcc actccttgct tttacctggg atgaccctga cacccatcag 3060 tcccagcagc ttacctgggc tgtactgcca caaggcttca ggggtagccc tcattacttc 3120 agccaagctc tttctcatga tttactttct ttccacccct ccacttctca ccttattcaa 3180 tatattgatg aacttctact ttggagcccc tcctttgaat cttctcaaca agacaccctc 3240 ctgctccttc aacatttatt ctccaaggga tatcgggtat ccccctccaa acctcaaatt 3300 tcttctccat ctgttaccta cctcggcata attcttcatg aaaacaaact tgctctccct 3360 gctgattgtg tctgactgat ctctcaaacc ctgacccctt ctacaaaaca acaactcctt 3420 tccttcctgg gaatggttgg ataattttta gaggccctca aaatcacaaa ctatgctcaa 3480 ctcactctct gcagttctca taacttccaa aatcaatttt cttcctcaca cctgacacat 3540 atactttctg ctccccgact ccttcagcta tactcactct ttgttgagtc tccctcaatt 3600 gccattgttc ctggcccaga cttcaatcta gcctcccaca ttattccaga taccacacct 3660 gacccccatg atggtatctc tctgatccac ctgacattca ccccatttcc ccatatttcc 3720 ttctttcctg ttcctcaccc tgatcacact tggtttattg atggcagttc caccaagcct 3780 aatcatcact caccagcaaa ggcaggcttt gctatattat ctttcacatt tatcattaag 3840 gctaccgctc tgccccctcc actacctctc agcaagccaa actcattgcc tttacttgag 3900 ccgtcactct tgaaaaggga ctacgtgtca atatttatac cgactctaaa tatgccttcc 3960 atatcctgca ccaccatgct gttatagggg cagaaagaag tttcctcact acacagggtt 4020 cctacatcat taatgcgtct ttaataaaaa ctcttctcaa ggccacttta cttccaaagg 4080 aagctggagt cattcactgc aaggaccatc aaaaggtgtc agatcccatt gctctgggga 4140 gcgcttatgc tgataaggta gctaaagaag cagctagtat tccaacttct gtccctcatg 4200 gccagttttt ctccttgtca ttggtcactc ccacctactc tcccatgaaa cttccaccta 4260 tcaatctctt cccacacaag gcaaatggtt cttagaccaa ggaaaatatc cccttccagc 4320 ctcacaggcc cattgtattc tgtcatcatt tcataacctc ttccatgtag gttacaagtt 4380 gctagcctgc ctctttagaa cctttcattt cctttccact gtggaaatct atcctcaagg 4440 aaatcacttc tcagtgtccc atctgctatt ctactacccc tcagggattg ttcaggcccc 4500 ctcctttccc tacacatcaa gctcagggat ttgctcctgt ccaggactgg caaattgact 4560 ttactcacat gccccgagtc aggaaactaa aatacctctt ggtctgggta gacactttca 4620 ctggatgtgt agaggacttt ctctcagggt ctgagaaggc caccatggtc atttcttccc 4680 ttctgtcaga cataattcct cagtttggcc ttctcacctg tatacagtcc aataacagac 4740 catcctttac tagtcaaatc acccaagcag tttctgaggc tcttggtatt cagtggaaac 4800 ttcatacccc ttaccattct caatcttcgg aaaggtagaa cagactaatg gtcttttaaa 4860 gacacatctc accaagctca gcctgtaact taaaaaggac tggacagtac ttttacctct 4920 tgcccttctc agaattagag cctgtcctca agatgctaca gggtacagtc catttaaact 4980 tttgcatgga cgtactttct tgcttggccc ccaacctcat cccagacacc agccctctag 5040 gcgactatcc tccagtcctc cagcaggcta gataggaaat ttgccaggct gctaatattc 5100 tcttgcctac tccagattcc cagccatatg aagacaccct agctggatgg tcagttcttg 5160 ttaagaatct gacccctcaa actctacaac ctcaatggac cggaccctac ttatctgtag 5220 taccccaact gccgtttgcc tgcaggatcc tccccactgg gtttactgtt ccagaataaa 5280 gctgtatcca ccagacagcc agcctaatct ctcctcttcc tcctggaagt ctcaagtact 5340 ctcccctact tcacttaaac tcactcacat ttttgaagaa cagtaataac tcttatgaac 5400 ctaatacatc gtttcattct attaggtcta ttcgtcctta ccctactttt tgcaacagga 5460 ctttatgcag tcacccccac tacttggcct gaccccccaa aacttgtcat ccctactgtc 5520 ttctgtccag tcatactcct attcaccatt ctcaactact cataaatgcc ctactcttgt 5580 ttacactgcc agtttacact gtttctccaa gccatcacag ctaatatctc ctggtgctat 5640 ccccaaacca ccactcttta ctccctctta gagtggatag atgatctttg gtggcaggac 5700 accctccaat actttcacca cactatcaat ctcattcact ctttcctagc catttctaat 5760 ccctccttag tgaacaattg ctggctttgc atttcccttt cttcctgtgc ctatacagct 5820 gtccccgcct tacagacaga ctgggaacat ctcctgtctc cctacacctc cgaacttcct 5880 ttaaccgccc tcacctttgc cctcctgaag aacttcttta ctttctagac aggtccagca 5940 agacctcctc agacatttca catcagcaag ctgccaccct cctccgcact tacttaaaaa 6000 acctttctcc ttatatcaac tctactcccc ccatatttgg acccctcaga acacaaacta 6060 ctattcctgt ggccactctt ttatgtatct ctcagcaaag acccactgga attcccctgg 6120 gtaacctttc atcttctcgg tgttccttca gtcttcatct ccaaagttca actacacaca 6180 tcactgaaac agttggaggc ttccagctcc atattacaga taaaacctct atcaatactg 6240 gcaaacttaa aaacatcagc agttattatt gcttaggaag acacttaccc tgtatttcac 6300 tccatccttg gctaccttcc ccttgctcgt cagactctcc tcccaggccc tcttcttatt 6360 tacttatacc cagccccata aataacagtg aaaggttgct catagacact caacgttttc 6420 tcacacacca tgaaaatcaa acctctatgc agttatccca tcagtcccca ttacaactgc 6480 tgatggctgt caccctagct ggatccctag gagtctgggt acaaaacagc ttttttagta 6540 ctccttctca tctttttact ttgcatttcc agttttgcct tgcacaaggt ctcttcttcc 6600 tctgtggatc ctctacctac atgcaaattg gacaggcaca tgcacactag ttttccttac 6660 tcccaaaatt caatttgcag atgggactga agagcttcct gttcccctca taacactgac 6720 acaacaaaaa agaattattc cactaattcc cttgcttgtc tgtttaggac tttctgcctc 6780 cactattgct cttggtactg ggatagcagg catttcaacc tctgtcatga ccttccatgg 6840 cctctctaat gactctccgc tagcatcaca gacatatcac aaactttatc agtccttcag 6900 gcccaagttg actctttagc tgcagttgtc ctccaaaacc tccaaggcct tgactttcac 6960 tgctgaaaaa ggaggactct atatttttaa atgaagagtg ttgtttttac ctaaatcaat 7020 ctggcctgat gtatgacaac ataaaaaaac tcaaggatag agcccaaaaa cttgccaacc 7080 aagcaagtaa ttatgctgaa cctccttggg cactctctaa ttggttgtct tgggtcctcc 7140 caattcttag tcatttaata cctgtttttc tccttctctt attcggacct tgtgtcttct 7200 gtttagtttc tcagttcatc caaaaccata tccaggctgt catcaatcat tctatatgac 7260 aaatactcct tctaacaacc ccacaatatc accccttacc acaaaatctt ccttcagctt 7320 aatctctccc attctaggtt ctcacgccac tcctaatccc acttgaagca gccctgagaa 7380 acatcaccca ttttctttcc ataccacccc caaaaatttt cacagcccca acacttcacc 7440 actattttgt ttttttctta ttaatataag aagacaggaa tgttaggcct ctgagcccaa 7500 gctaagccat catataccct gtgacctgca catatacatc cagatggcct gaagcaactg 7560 aagatccaca aaagaagtga aaaaagcaat aactgatgac attccaccat tgtgatttgt 7620 tcttgcccca ccctacatgt attctcccct gcccttaaga aggtactttg taatattctc 7680 tcccaccgct gccccctgcc tttaagaagg tactttgtaa tattctcccc tacccttaag 7740 aatgtacttt gtatgcctat tcttaaacgt ataagaacta atgataatcc caccaccctt 7800 tgctgactct cttttcggac tcagcctgcc tgaatatagg tgaaataaac agacttgttg 7860 ctcacacaaa gcctgtttgg tggtctcttc acacggacac gcatga 7906 <210> 251 <211> 5722 <212> DNA <213> Homo sapiens <400> 251 gtcaggcctc tgagcccaag ccaagccatc gcatccccta tgacatgcac gtacacgccc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa tatgccctgc cccaccttaa 120 ctgatgacat tccaccacaa aagaagtgta aatggccagt ccttgcctta actgatgaca 180 ttaccttgtg aaagtccttt tcctggctca tcctggctca aaaagcaccc ccactgagca 240 ccttgcgacc ccccgctcct acccgccaga gaacaaaccc cctttgactg taattttcct 300 ttacctaacc aaatcctata aaacggcccc acccttatct cccttcgctg actctctttt 360 cggactcagc ccgcctgcac ccaggtgaaa taaacagcct cgttgctcac acaaagcctg 420 tttggtggtc tcttcacacg gacgcgcatg aaatttggtg ccgtgactcg gatcggggga 480 cctcccttgg gagatcaatc ccctgtcctc ctgctctttg ctccgtgaga aagatccacc 540 tacgacctca ggtcctcaga ccaaccagcc caagaaacat ctcaccaatt tcaaatccgg 600 taagcggcct ctttttactc tgttctccaa cctccctcac tatccctcaa cctctttctc 660 ctttcaatct tggcgccaca cttcaatctc tcccttctct taatttcaat tcctttcatt 720 ctctggtaga gacaaaagag acatgtttta tccgtgaacc caaaactccg gcgccggtca 780 cggactggga aggcagtctt cccttggtgt ttaatcattg cagggacgcc tctctgattt 840 cacgtttcag accacgcagg gatgcctgcc ttggtccttc acccttagcg gcaagtcccg 900 ctttcctggg gcaggggcaa gtacccctca accccttctc cttcaccctt agcggcaagt 960 cccgcttttc tggggcaggg gcaagtaccc ctcaacccct tctccttcac ccttagcagc 1020 aagtcccgct ttcctagggg gcaagaaccc cccaatcgct tattttcacg ccccaacctc 1080 ttatctctgt gccccaatcc cttatttcca cgccccaatc tcttatctct gcgccccaat 1140 cccttatttc cgcgccccaa ccctttctct gcttttctgg aggggaagaa acccccaccc 1200 cttctccgtg tctctactct tttctctggg cttgcctcct tcactatggg caagcttcca 1260 ccttccattc ctttcttctc ccttagcatg tattcttaag aacttaaaat ctcttcaatt 1320 ctcacctgac ctaaaatcta agcgtcttat tttcttctgc aatgccactt gaccccaata 1380 caaactcaac agtagttcca aatagccaga aaatggcact ttcaattttt ccaccctaca 1440 agatctaaat aattcttggc gtaaaatggg caaatggtgt gaggtgcctg acgtccaggc 1500 attcttttac acatcagtcc cttcctagtc tctgtgccca gtgcaactcg tcccaaatct 1560 tccttctttc cctcccgcct gtcccctcag taccaacccc aagcgtcact gagtctttct 1620 aatcttcctt ttctacagac ccatctgacc tctcccttcc tccccaggct gctccttgcc 1680 aggccgagct aggtcccaat tcttcctcag cctctgctcc tccaccctat aatcttttta 1740 tcacctcccc tcctcacacc tgctccggct tacagtttca ttccgtgact agccctcccc 1800 gacctgccca gcaatttatt cttaaaaagg tggctggagc taaacgcata gtcaaggtta 1860 atgctccttt ttctttatcc caaatcagat agtgtttagg ctctttttca tcaaatataa 1920 aaatctagcc cagttcatgg ctcgtttggc agcaacccta agacacttta cagccctagc 1980 ccctaaaagg tcaaaaggcc atcttattct caatatacat tttattaccc aatctgctcc 2040 cgacattaaa taaaactcca aaaactggaa tctggccctc aaaccccaca acaggactta 2100 attaacctca ccttcaaggt gtgaaataac agaaaaaagt tgcaattcct tgcctccact 2160 gtgagacaaa ccccagccac atctccagca cacaagaact tccaaacgcc tgaactgtag 2220 cagccagacg tttctccaga acctcctccc ccaggaactt gctacacatg ccggaaatct 2280 ggccactggg ccaaggaacg cccgcagccc gggattcctc ctaagccgcg tcccatctgt 2340 gtgggacccc actgaaaatc ggactgttca actcacctgg cagccactcc cagagctcct 2400 ggaactctgg cccaaggttc tctgactgac tccttcttgg cttactggct gaagactgac 2460 gctgcctgat cgcctcagaa gccccgcaga ccatcatgga cgccgagctt taggtaactc 2520 acagtggagg gtaagtccgt ccccttctta atcaatacgg aggctaccca ctccacatta 2580 ccttcttttc aagggtctgt ttcccttgcc tccataactg ttgtgagtat tgacagccag 2640 gcttctaaac ctcttaaaac tccccaactc tggtgccaac ttagacaata ctctttaaag 2700 cactcctttt tagttatccc cacctgccca gttcccttat taggctgaga cactttaact 2760 aaattgtctg cttccctgac tattcctgga ctacagctat atctcattgc cgcccttctt 2820 cccaatcaaa agcctccttt gcgtcctcct cttgtatccc cccaccttaa cccacaagta 2880 taagatacgt ctactccctc cttggtgacc gatcatgcac cccttaccat ctcattaaaa 2940 cctaatcacc cttaccctac tcaacgccaa tatcccatcc cgcagcacac tttaaaaagg 3000 ttaaagcctg ttatcactcg tctgctacag catggccttt taaagcctat aaactcccct 3060 tacaattccc ccattttacc tgtcctaaaa ccggacaagc cttacaagtt agttcaggat 3120 ctgtgcctta tcaaccaaat tgttttgcct atccaccccg tggtgccaaa cccgtatact 3180 ctcctatcct caatacctcc ctctactacc cattagtctg ttctagaact caaacatgct 3240 ttctttacta ttcctttgca cccttcatcc cagcctctct ttgctttcac ttagactcac 3300 cctgacactg attaggctca gcaaattacc tgggctgtac tgccacaagg cttcacagac 3360 agcccccatt acttcagtca agcccaaatt tcatcctcat ctgttaccta tctcggcata 3420 attctcataa aaacacacgt gctttccctg ctgatcgtgt ccgattaatc tcccaaacct 3480 caatccctta caaaacaaca actcctttcc ttcctaggca tggttatagt gcagtcagaa 3540 ttcttacaca agagccagga ccacaccctg tagcctttct gtccaaacaa cttgacctta 3600 ctgttttagc ctagccctca tgtctgcgtg cagaggctgc cgctgcttta atacttttag 3660 aggccctaaa aatcacaaac tatgctcaac tcactctcta catttctcat aacttccaaa 3720 atctattttc ttcctcatac ctgacgcata tgctttctgc tccctggctc cttcagctgt 3780 actcactctt tgttaagtcc cacaattacc attgttcctg gcccggactt caatccggcc 3840 tcccacatta ttcttgatac cacacctgac ccccacgact gtgtctctct gatccacctg 3900 atattcaccc cattttccca tatttccttc tttcctgttc ctcaccctga tcacgcttga 3960 tttattgatg gtagttccac caggcctaat cgccacatac cagcaaaggc aggctatgct 4020 atagtactag ccactagcct gcctctcaga acctctcatt tcctttccat cgtggaaatc 4080 tatcctcaag gaaataactt ctcagtgttc catctgctat tctactactc ctcagggatt 4140 attcaggccc cctcccttcc ctacacatca agctcaggga tttgccccca cccaggactg 4200 gcaaattagc tttacttaac atgcccgagt caggaaacta aaatacctct tagtctaaat 4260 agacactttc actgaataag taaaggcgtt tcctacaggg tctgagaagg ccaccagtca 4320 tttcttccgt tctgtcagac ataattcctc attttagcct tcccacctca atacagtctg 4380 ataacagatg agtctttatt agtcaaatca gccaagcagt ttttcaggct cttagtattc 4440 agtgaaacct ttatatccct tacagtcctc catcttcaag aaaggtagaa tggactgaag 4500 gtcttttaaa aacacacctc accaagctca gccaccaaaa aggactggac aatactttta 4560 tcactttccc ttctcagaat tcaggcctgt cctcggaatg ctacaaggta cagcccattt 4620 aagctcctgt atagatgctc ctttttatta ggccccagtc tcattccaga caccggacca 4680 acttagactg tgcccccaaa aaaacttgtc atccctacta ttttctgtct agtcatactc 4740 ctattttcca ttctcaacta ctcatacatg ccctgctctt gtttacactg ccggtttaca 4800 ctgtttctcc aagccatcat agctgatatc tcctggtgct atccccaaac cgccactctt 4860 aactcttgaa gtaaataaat aatctttgct ggcaggacta tgctgaattt ccttaggcac 4920 tctctaatca gatgccctag gtcctcccaa ttcttagacc ttttatacct gtttttctcc 4980 ttcttattcc atttagtttt tcagttcata caaaaccgta tccaggccat caccaatcat 5040 tctatacaac aaatgtttct tctaacaacc ccacaatatc accccttacc ataagatctc 5100 ctttcagctt aatctctccg actctaggtt cccacaccgc ccctaatccc gcttgaagca 5160 gccctgagaa acatcgtcca ctctctctcc ataccactcc acaaaaattt tccccgcccc 5220 aacacttcaa cactatcttg ttttattttt cttattaaga aggcaggaat gtcaggcctc 5280 tgagcccaag ccaagccatt gcatcccctg tgacctgcat gtatatgccc agatggcctg 5340 aagtaactaa agaatcacaa aagaagtgaa tatgccctgc cccaccttaa ctgatgacat 5400 tccaccacaa aagaagtgta aatggccagt ccttgcctta actgatgaca ttaccttgtg 5460 aaagtccttt tcctggctca tcctggctca aaaagcaccc ccactgagca ccttgcgacc 5520 cccgctccta cccgccagag aacaaacccc ctttgactgt aattttcctt tacctaccca 5580 aatcctataa aacggcccca cccttatctc ccttcgctga ctctcttttc cgactcagcc 5640 cgcctgcacc caggtgaaat aaacagcctt gttgctcaca caaagcctgt ttggtggtct 5700 cttcacacag acgcgcatga aa 5722 <210> 252 <211> 547 <212> DNA <213> Homo sapiens <400> 252 acagtaggca gctagtcagg catgagcagg gcagggagag ggccccaccc caccacacca 60 ggaatgtcag ctgaccatca ggcgatggtc agccagttgt tacactgtct ctctagaatg 120 ataattgttt gcagcccgtg ccagggaaag gcagtttccc aagagattag aaacacctga 180 agctggtgat cagcagcttc ctgataagat ctctgtagtt gggtgagtgg gctccagcaa 240 gtgtattaag aggcaaaatg gcagagatca actggtgtat gacctcccag ggacattctg 300 cgggtaaagg gaaagaagac ctcaagtgag ctccactcaa cactctgtgc atgctcacct 360 cctaagtgct agcaggccac tgtgcatgtg agcagctggc cccaagggaa gaatcaggga 420 agaagggaag caagacccca gaagtatacc aactcataaa accccaagtc aaaaggtcaa 480 gccacgcatt taattttcaa cttgaccact tggccctctt ccaagtgtat gtgctttctt 540 tacattc 547 <210> 253 <211> 7695 <212> DNA <213> Homo sapiens <400> 253 gtcaggcctc tgagcccaag ccaagccatt gcatcccctg tgacttgcac atatatgccc 60 agatgtcctg aagtaactga agaatcacaa aagaagtgaa tatgccctgc cccaccttaa 120 ctgatgacac tccaccacaa aagaagtgta aatggctggt ccttgcctta agtgatgaca 180 ttaccttgtg aaagtccttt tcctagctca tcctggctag gtgattttaa atcaccccca 240 ctgagcacct tgtgaccccc actcctgcct gccagagaac aaaccccctt tgactgcaat 300 tttcctttac ctacccaaat cctataaaac agccccaccc ttatctccct ttgctgactc 360 tcttttcgga ctcagcccgc ctgcactcag gtgaaataaa cagccatgtt gctcacacaa 420 agcctgtttg gtggtctctt cacaaggatg cacatgaaat ttggtgccgt gactcggatt 480 gtgggacctc ccttgggaga tcaatcccct gtcctcctgt tctttgctcc gtgagaaaga 540 tccacctacg acctcaggtc ctcagaccga ccagcccaag aaacatctca ccaacttcaa 600 atccagtaag cggcctcttt ttactctctt ctccaacctc cctcactatc cctcaacctc 660 tttctccttt caatcttggc gccacacttc aatctctccc ttctcttaat ttcaattcct 720 ttcattttct ggtagagaca aaggagacac cttttatcca tggacccaaa actccggcgc 780 cggtcacaga ctgggaaggc agccttccct tggtgtttaa tcattgcagg gacgcctctc 840 tgattattca cccacgtttc aagggtgtca gaccacgcag ggacgcctgc cttggtcctt 900 cacccttagc agcaagtccc acttttctgg gaaaggggca agtacctcaa ccccttctct 960 ccatgtctct accccttctc tgcttttctg ggggaggggc aagtacccct caaccccttc 1020 tccttcactc ttagtggcaa gtcccacttt tctagggggc aagaaccccc aatcccttat 1080 ttctgcaccc caacctctta tctctgcacc ccaatccctt atttcctcac cctgacctct 1140 tatctctgtg ccccaatccc ttatttccgc acccagacct cttatctctg tgccccaatc 1200 ccttatttcc atgccccaac cccccttccc gcttttctgg agggtaagaa cccctgaacc 1260 ccttccctcc atgtctctac tctctctttt ctctgggttt gcctccttca ctataggcaa 1320 aattccaccc tccattcctc cttcttctcc tttagcctgt gtcctcaaga acttaaaacc 1380 tcaacttaca cctgtcctaa aacctaaacg ccttattttc ttctgcaaca ctgcttggct 1440 ccaatacaaa cttgacaatg gctctaaatg gccagaaaat ggcactttcg atttctccat 1500 cctacaagat ctaaataatt cttgtcttaa aataggcaaa tggtctgagg tgcctgatgt 1560 ccaggcattc ttttacacat cagtcccttc ctagtctctg tgcccagtgc aacttgtccc 1620 aaatcttcct tgtttccctc ccgcctgtcc cctcagtccc aaccccaagc atcgctgagt 1680 ctttctaatc ttccttttct acagacccat ctgacctctc ccctccttgc caggccaagc 1740 taggtcccaa ttcttcctca gcctccactc ctccaccctg taatcttttt atcgcctcac 1800 ctcctcacac ctggtccggc ttacagtttc gttccatcac tagcccttcc ccacctgccc 1860 agcaatttac tcttaaaaag gtgcctggag ccaaaggcat agtcaaggtt aatgctcctt 1920 tttctttatc ccaaatcaga agcgtttagg ctctttttca tcaaatataa aaacccagcc 1980 cagttcatgg ctcattcggc agcaaccctg agacgcttta cagccctaga ccctaaaagg 2040 tcaaaaggcc atcttattct caatatacat tttattaccc aatctgctcc cgacattaaa 2100 taaaactcca aaaattagaa tctggccctc acaccccaca acaggactta attaacctca 2160 ccttcaaggt gtacaatgat aaaaaaaaaa agttgcaatt ccctgcctcc actgtgagac 2220 aaaccccagc cacatcccca gcacacaaga acttccaaac acctgaaccg cagtggccag 2280 gcgttcctcc agaacctcct ccccgaggag cttgctacaa gtgccagaaa tctgaccacc 2340 aggccaagga atgcctgcag cccaggattc ccccatctgt gtgggacccc actggaaatc 2400 agactgttca actcacctgg cagccactcc cagagcccct ggaactctgg cccaaggctc 2460 tctgactgac tccttcttgg cttagcggct gaagactgac acagcctgat cgcctcggaa 2520 gccccataga ccatcacaga tgccgagctt taggtaactc tcacagtgga gggtaagtcc 2580 atccccttct taatcaatac agaggctacc cactccacat taccttcttt tcaagagcct 2640 gtttcccttg cctccataac tgttgtgggt attgatgccc aggcttctaa acctcttaaa 2700 actccccaac tctggtgcca acttagacaa tactctttta tgcactcttt tttagttatc 2760 cccacctgcc cagttccctt attaggccga gatattttaa ccaaattatc tgcttccctg 2820 actattcctg gactatagcc gcatctcatt gctgcccttc ttcccaatcc aaagcctcct 2880 ttgcgtcctc ttcttgtatt cccccacctt aacccacaag tataagatac ctctactccc 2940 tccttggcga ccaatcatgc tccccttacc atctcgttaa aacctaatca cccttaccct 3000 gctcaatgcc aagatcccat cccacagcac gctttaaaag gattaaagcc tgttatcact 3060 cgcctgctaa ggcatggcct tttaaagcct ataaactctc cttaccattc ccccatttta 3120 cctgtcctaa aaccagacaa gccttacaag ttagttcaga atctgcacct tatcaaccaa 3180 attgttttgc ctatccaccc cgtggggcca aacccatata acctcctatc ctcaatacct 3240 ccctctacta cccattattc tgttctggat ctcaaacatg ctttctttac tattcctttg 3300 cacccttcat cccagcctct ctttgctttc acttagactg accctgacac ccattaggct 3360 cagcaaatta cctgggctgt actgccacaa ggtttcacag acagccccca ttacttcagt 3420 caagcccaaa tttcatcgtc atctgttacc tatctcggca taattctcat aaaaacacac 3480 gtgctctccc tgctgatcct gtccgattaa tctcccaaac ctcaatccct tacaaaacaa 3540 caactccttt ccttcctagg catggttagt gcagtcagaa ttcttacaca agagccagga 3600 ctgcaccctg tagcctttct gtccaaacaa cttgatctta ctgttttagc ctagccctca 3660 tgtctgcatg cagcagctgc cactgcttta atacttttag aggccctaaa aatcacaaac 3720 tatgctcaac tcactctcta catttctcat aacttccaaa atctattttc ttcctcatac 3780 ctgatgcata tactttctgc tccttggctc cttcagctgt actcactctt tgttaagtct 3840 cccacaatta ccatcattcc tggcccggac ttcagtccag cctcccacat tattccagaa 3900 accacacctg accctcatga ctgtatctct ctgatccacc tgacattcac cccatttccc 3960 catatctcct tctttcctgt tcctcaccct gatcatgctt gatttattga tggcagttcc 4020 accaggccta atcaccacac accagcaaag gcaggctatg ctatagtaca agccactagc 4080 ctgcctctta gaacctctca tttcctttcc attgtagaaa tctatcctca aggaaatcac 4140 ttctcagtgt tccatctgct attctatgtg ctattctact actcctcaag gattattcag 4200 gccccctccc ttccctacac atcaagctcg aggatttgcc cctgcccagg actggcaaat 4260 tagctttact caacatgccc tgagtcacaa aaactaaaat acctcttagt ctaagtagac 4320 actttcacta gataggtaga ggcctttcct acagggtctg agaagggcac cgcagtcatt 4380 tcttcccttc tgtcagacat aattcctcag tttagccttc ccacctctat acagtctgat 4440 aacagaccag cctttattag tcaaatcagc caagcagttt ttcaggctct tagtattcag 4500 tgaaaccttt atatccctta tagtcctctg tcttcaagaa aagtagaacg gactaaaggt 4560 cttttaaaaa cacacctcac caagctcagc caccaactta aaaagaactg gacaatactt 4620 tcaccacttt cccttctcag aagtcagacc tgtcctcgga atgctataag gtacagccca 4680 tttaagttcc tgtatagatg ctccttttca ttaggccccc agtctcattc cagacaccgg 4740 accaccttag actgtgcccc aaaaaaactt gtcatcccta ctattttcta tctagtcata 4800 ctcctgttct ctgttctcaa ctactcatac atgccctgct cttgtttaca ctgccagttt 4860 acactgtttt ttcaagccat cacagctgat atctcctcgt gctatcccca aaccgccgct 4920 cttaactctt gaagtaaata aataatcttt gctggcagga ctatgctgaa tctccttagg 4980 cactctctaa tcagatgtcc taggtcctcc cgattcttag accttttata cctgtttttc 5040 tccttctctt attccattta gtttttcaat tcatacaaaa ccatatccag gccatcacca 5100 atcattctat acgacaaatg tttcttctaa catccccaca atatcacccc ttaccacaag 5160 acctcccttc agcttaatct ctcccactct aggttcccac gccgccccta atcccgcttg 5220 aagcagccct gggaaacatc gcccattctc tctccatacc accctccaaa aattttcgcc 5280 accccaacac ttcaacacta ttttgtttta tttttcttat taatataaga aggcaggaat 5340 gtcaggcctc tgagcccaag ccaagctatc ccatcccctg tgacttgcac atatacgccc 5400 agatggcctg aagtaactga agaatcacaa aagaagtgaa tatgccctgc cccaccttaa 5460 ctgatgacat tccaccacaa aagcagtgaa aatggccggt ccttgcctta agtgatgaca 5520 ttaccttgtg aaagtccttt tcctagctca tcctggctca aaaatcaccc ccactgagca 5580 ccttgcgacc cccactcctg cccgccagag aacaaacccc ctttgactgt aattttcctc 5640 tacctaccca aatcctataa aacggcccca cccttatctc ccttcgctga ctctcttttc 5700 ggactcagcc cgcctgcacc caggtgaaat aaacagccat gttgctcaca caaagcctgt 5760 ttggtggtct cttcacacgg acacgcataa aagcaagtag ccaccatagt ggacagtaca 5820 ggcctagtgt ccagcatgat gcctgacaaa tgaaagatgc ttaataaact cttcttaagt 5880 gtatgaaagg atggagtaga ataattttta ctctgctttg cactgtccag actacacatc 5940 tgaaatatta tgttctgttc caggcaccaa attttaagag ggttagtatc aacctagact 6000 atagaaggaa gtaggatgat aacagtccca aaacatcagc catagttggc agaacttgga 6060 atgttttgta tgaaaaataa tagcctttgc atgaaatcaa actaaatgcc catcaatgac 6120 agattggata aagaaaatgt ggtacatata cacatggaat actatgcagc cataaaaaaa 6180 cagatagtgt cttttgcagg aacatggatg gagctagaag ctattatcct tagcaaacta 6240 atgcagggaa aaaaccaaat acgacatgtt ctgacttata agtgggagct aaatgatgag 6300 aactcatgaa cacaaagaag agaacaacag acacaggggt ctacttgaga gtgggaggag 6360 ggagaggagc agaaaaacaa gtattggcta ctaggcttaa tacctgggtg atgaaataat 6420 ctgtacaaca aacccccatg gcacgagttt acctacgtaa caaagcttca catgtacccc 6480 caaacctaaa ataaaagtta aaaaaaagga aaataatcat atttggattc attttaggtt 6540 ttgttttgtt ttgttttgtt tttgtatgcc tttggtctgg atcaaagttt ttttttttaa 6600 ttaaagggtt ggattaggca atgttttagg cccacgtaag atagaaaagt ctatgatacg 6660 atagttcttc ctgtagaaga ggaagtagac tctcatagag cagaaatttg atgaccttgg 6720 aggatactag atacatccac acatggggaa gaactttctg agaacagtgc aggaacggaa 6780 tgagggagcc agtgagcttc ttccctggaa atacacaaga agagcctctc aaagttcaaa 6840 tcatgaatga atgcagtctt ctttccagcc acaaacattt cccagaattg gtattttagg 6900 gcagcacatg gatttccaga gcttccaatc attaataata gttactaatg caaaagttac 6960 acctcatgct tgtgtctttc agaattgtgt ctgagtgcgg tcagttcatc ttaagtgaca 7020 gggtttcgcc caccagccaa atgattttgg attattgaag gagttggtca tgaagaatat 7080 gttttcacaa ggaaagtatg catatacatt ccaaataaca tggttgtggg atagtcacca 7140 tgaccagaat ttcagctttc tgggacccag tgcttccacc tccaactgtg ctatggagag 7200 agagccactg cctttccagg taccatgtat gttataattg acagtgtcag gcctctgagc 7260 ccaagccaag ccatcacatc ccctgtgact tgcacatata tgcccagatg gcctgaagta 7320 actgaagaat cacaaaagaa gtgaaaatgc cctgccccgc cttaactgat gacattccac 7380 cacaaaagaa gtgaaaatgg ctggtccttg ccttaagtga tgacattacc ttgtgaaagt 7440 cccttttcct ggctcatcct ggctcaaaaa gctcccccac tgagcacctt gtgaccccca 7500 ctcctgcccg ccagagaaca agtccccttt gactgtaatt ttcctttatc tacccaaatc 7560 ctataaaacg gccccaccct tatctccctt cgctgactct tttcggactc agcctgcctg 7620 cacccaggtg attaaaaagc tttattgctc acacaaagcc tgtttggtgg tctcttcaca 7680 cggacgcgca tgaaa 7695 <210> 254 <211> 7162 <212> DNA <213> Homo sapiens <400> 254 gcaaccccct ttgggacccc tccctttgta tgggagctct gttttcactc tatttcactc 60 tattaaatct tgcaactgca ctcttctggt ccgtgtttgt tacggctcga gctgagcttt 120 cactcaccgt ccaccactgc tgtttgccac catcgcagac ccgccgctga cttccattcc 180 tccagatccg gcagagtatc tgctgtgctc ctgatccagt gaggcgccca ttgccacttc 240 caatcaggct aaaggctcgc cattgttcct gcatggctaa gtgcctgggt tcatcctaat 300 cgagctaaac actagtcact ggcttccatg gttctctccc atgacccaca gcttctaata 360 gagctataac actcaccgca tggcccaaga ttccattcct tggaattcgt gaggccaaga 420 accccaggtc agagaacacg aggcttgccg ccatcttgga agtggctcac caccatcttg 480 ggagctctgg gagcaaggac cccccacccc ccgtaacatt ttggcaacca cgaagggaca 540 tccaaagcag tgagtaatat tggaccactt tcgcttgcta tactgtccta gccttcctta 600 gaggtggagg aaaataccgg acacctgtcg gccagttaaa aacgattagc gtggccgcct 660 gacttaagac tcaggtgtga ggctatctgg ggaagggctt tctaacaacc cccaaccctt 720 ctggggttgt tggggacatt ggtctgcctg gagccagctt ccactttcaa ttttcttggg 780 gaaaccaagg gccaactaga ggcagaaagc tgtcgtccca acctcccagc agtagctgat 840 tgagatcatg gctcagccag aagtctctac tcaacagtcg cccacgcatg cgcccttacc 900 tttccttctg acccatacct cctgggtccc gaacacgact ttcttgaaag tatagcccca 960 aaattctcct tacctctgaa tctacttcct ctgatccctg cctcctaggt actaatggtt 1020 cagactttca tttcctctag caggttgtat ctccaaaggg atctaaggaa gccctacgct 1080 gcgtcctcag gcacctaggc tatagcccag ggagtcttat ccctggcgtc cctcctaatt 1140 taggtataca gctcttgaca tgagcagtta tgcaggaccc attccccacc acccttgcca 1200 gggccccaag tttgtaatgg ctaagagaga gacacggaga gagagagatg gagagagaga 1260 gagagagatg aagagagaga gagagacaga gaggcaggtt cttggcctca cggattccaa 1320 ggaagtcaaa gagtaaaaga aagaaaaaga aatagttaaa aaaaaaaaag tgtgccctat 1380 tcctttaaaa gccagggtaa atttgaaacc cataattgat aattgaagat cttctctatg 1440 aacctataac actccaatgc cactttgttg tcagtgtaaa taagggcgta gcccgaaagc 1500 actgaggcca ctgacaaccc atagccttcc tgtctaaaat ccttaaccca gtaacccacg 1560 gatgagccaa atgcattcag ttggtagcgg caactgcttt gctaaaagta gaaaagtaac 1620 ttttagagga aacttcgctg tgagcacacc tcaccagttc agaattagtc taagtcaaaa 1680 aagcaaagag gtagcttact aactcaaaaa tcttaaagta tggggccatt atgttagaaa 1740 aaagtaatgt aactccaacc gctgataatt cccttaaccc agcagatttt ctaacagggg 1800 atttacatct taattaccat acaaaggtcc gaccagacct aggaggatct tccttcagga 1860 caggatgata gatggttcct cccaggtgat tgaggtaaaa aacacaatgg gtattcagta 1920 attgatacgg agactcttgt ggaagcagag ttagaaaaat tgcctaataa ttggtctcct 1980 caaatgtgcg agctgtttgc actcagccaa gccttaaagt acttacagaa tcaaaagact 2040 atctcaatcc tgactcaaaa ggttcgctac accctctctg aaacgaattt gcataaaaac 2100 tgttgtttat gggaatgcat cttgatgggg cagctgggtt gttatgaaat actcaggaac 2160 ccagcccagc tctaggactc actcctgagc gcaaaggcaa tgttgggcac gctggtaaag 2220 gaccactaga atccagcagc ccggacccct ttctttgtgg tcaagaaagg cgggaaaaca 2280 ggtgcaggac tgctacatcg gtgagtgtaa ctaatccgat aagcagaggt ccatgggtgg 2340 ttacgcaccc tggaaaggaa taagcattag gaccacagag gacactctag gactaatgct 2400 catcagaaaa tgactaggga tgctggcatc cctatgttcc tttttcagat gggaaacgtt 2460 ccccccaagg caaaattgcc cctaagatgt attctggaga attaggacca atttgaccct 2520 cagacgctaa gaaagaaatg acttatattc ttctgcagta ccgcctggcc gtgatattct 2580 cttcaagggg aagaaagctg gcctcctgag ggaagtataa attataacac catcttacag 2640 ctagacctct tttgtagaaa agaaggcaaa tggagtgaag tgccatatgt acaaactttc 2700 ttttcattaa gagacaactc gcagttatgc aaaaagtatg acttatgccc tacaggaagc 2760 cctcagaatc tacctcccta ccccaacatc cccctgactc cttccccaac taataagaac 2820 cccctcttca gcccaaatgg tccaaaagga gatagacaaa ggggtaaaca atgaaccaaa 2880 gagtgccaat attccccgat tatgccccct ccaagcagcg ggaggaggag aattcagccc 2940 agccagagtg catgtaactt tttctctctc agacttaaag caaattaaaa tagacctagg 3000 taaattctca gataaccctg atggctatat tgatgtttta caagggttag gacaatcctt 3060 tgatctgaca tggagagata taatgttact gctaaatcag acactaaccc caaatgaaaa 3120 agtgccacca ttactgcagc ctgagagttt ggcgatctct ggtatctcag tcaggtcaat 3180 gacaggatga caacagaaga aagagaatga ttccccacag ggcagcaggc agtccccagt 3240 gtagaccctc actggcacac agaatcagaa catggagatt ggtgccgcag acatttgctc 3300 acgtgtgtgc tagaaggact aaggaaaact aggaagaagg ctgtgaatta ttcaatgatg 3360 tacactatag catagggaaa ggaagaaaat cctactgcct ttctggagag actaagggag 3420 gcattgagga agcatacctc cctgtcacct gactctagtg aaggccaact aatcttaaag 3480 gataagttta tcactcagtc agctgcagac attaggaaaa aacttcaaaa gtctgtctta 3540 ggcctggagc aaaacttaga aaccctattg aacttggcaa cctcgctttt ttataataga 3600 gatcaggagg agcaggcaga acaggacaaa caggataaaa aaaaggccat cactttagtc 3660 atggccctca ggcaagtgga ctttggaggc tctgtaaaag ggaaaagctg ggcaaatcga 3720 atgcctaata gggcttactt ccagtgcggt ctacaaggac actttaaaaa agattgtcca 3780 agtagaagta agccgccctc ttgtccatgc cccttatgtc aagggaatca ctggaaggcc 3840 cactgcccca ggggatgaag gtcctctgag tcagaagaca ctaaccagat gatccagcag 3900 cagggctgag ggtgcccagg gcaagcgcca gcccatgcca tcaccctcac agagccccag 3960 gtatgcttga ccattgagag ccaagaggtt aactgtctcc tggacgccgg tgcggccttc 4020 tcagtcttac tctcctgtcc cggacaactg tcctccagat ctgtcactat ccgaggggtc 4080 ctaggacagc cagtcactag atacttcttc cagccactaa gttgtgactg gggagcttta 4140 cccttttcac atgctttcct aattatgcct gaaagcctca ctcccttgtt agagagagag 4200 attctagtaa aagcaggggc cattatacac ctgaacatag gagaaggaac acccatttgt 4260 cgtctcctgt ttgaggaagg aattagtcct gaagtctggg caacagaagg acaatatgga 4320 caagcaaaga atgcccattt tgtccaagtt aaactaaagg attccacctc ctttccctat 4380 caaaggcagt accccctcag acccgaggcc caacaaagac tccaaaagat tgttaaggac 4440 ctaaaagccc aaggcctagt aaaaccatac agtagcccct gcaatactcc aattttagga 4500 gtacagaaac ccaaaagaca gtggaggtta gtgcaagatc tcaggattat caatgaggct 4560 gtttttcctc tatacccagc tatacctagc ccttatactc tgctttccca aataccagag 4620 gaagcagagt ggtttacagt cctggatctt aaggatgcct ttttctgcat ccctgtacat 4680 cctgactctc aattcttgtt tgcatttgaa gatccttcaa acccaacatc tcaactcacc 4740 tggactgttt taccccaagg gttcagggat agtccccatc tatttggcca ggcattagcc 4800 caagacttga gccagttctc atacctggac actcctgtcc ttcagtgcat ggatgattta 4860 cttttagctg cccgttcaga aaccttgtgc catcaagcca cccaagcgct cttaaatttc 4920 ctcactacct gtggctacaa ggtttccaaa ccaaaggctc agctctgctc acagcaggtt 4980 aaatgcttag ggctaaaatt atccaaagtc accagggccc tcagtgagga acgtatccag 5040 cctatactgg cttatcctta tcccaaaacc ctaaagcaac taagagggtt ccttggcata 5100 acaggtttct gccgaatatg gattcccagg tacggcaaaa tagccagacc gttatatacg 5160 ctaattaagg aaactcagaa agccaatacc catttagtaa gatggacacc tgaagcagaa 5220 gcagctttcc atgccctaaa gaaggcccta atgcaagccc cagtgctaag cttgctaacg 5280 gggcaagact tttcctcata tgtcacaaaa aacaaacaaa caaagaaaaa aaaaaacatg 5340 aatagctcta agagtccttg cgctggtctg agggacgagt ttgcaacccg tggcatacct 5400 gagtaaggaa attgatgtag tggcaaaggg tcagcctcat tgtttacggg tagtggtggc 5460 agtagcagtc ttagtatctg aagcagttaa aataatacag ggaagaaatc ttactgtgtg 5520 gacatctcat gatgtgaatg gcatactcac tgctaaagga gacttgtggc tgtcagacaa 5580 ccatttactt aaatatcagg ctctattact tgaagggcca atgctgcgac tgtgcacttg 5640 tgcagctctt aacctggaca catttcttcc acacaatgaa gaaaagatag aacataactg 5700 tcaacaagta attgctcaaa cctatgccac tcgaggggac catttagagg ttcccttgac 5760 tgatcccaac cctaacttgt atactgatgg aagatccttt gtagaaaaag gacttcaaaa 5820 agtggggtat gcagtagtca gtgataatgg aatacttgaa agtaatcccc tcactccagg 5880 aactagtgct cagctggcaa aactcactcg ggcactagaa ttaggagaag gaaaaagggt 5940 aaatatatat acagactcta agtatgctta cctagtcctc catgcccatg cagtaatatg 6000 gagagaaagg gaattcctaa cttctgaggg aacacctatc aaacatcagg aagccattag 6060 ggaattatta ttggccgtac agaaacctaa agaggtggca gtcttacact gccggggtca 6120 tcagaaagga aaggaaaggg aaatagaaag gaaccgccaa gcagatattg aagccaaaag 6180 agctgcaagg caggaccctc cattagaaat gcttatagaa ggacccctag tatggggtaa 6240 tcccctctgg gaaaccaagc cccagtattc agaagaagaa atagaatggg gaatctcacg 6300 aggacatagt tttctcccct caggatggca agccaccgaa caaggaaaaa tacctttgcc 6360 tgcagctaac caatggaaat tacttaaaac cactcaccaa aactttcact tatgcattga 6420 tagcacccat cagatggcca aattgttatt tactggacca ggacttttca aaactctcaa 6480 gcagatagtt ggggcctgta aagtgtgcca aagaagtatc cccaggccat acatttgaat 6540 ccctgtatct ttaacctcct tgttaagttt gtctcttcca gaattaaagc tgtaaaacta 6600 caaatcattc ttcaaatgga gccccagatg cagtccatga ctaagatcta ccgcggaccc 6660 ctggaccacc ctgacagccc atgctccaat gttaacgaca tcgaaggcac ccctcctgag 6720 gaaatctcaa ctgcacaacc cctactacac cccaggccag caggaagcag ttagagcagt 6780 catcgccaac ctccccaaca gcacttgggt tttcctgttg agagagagga ctgacagaca 6840 ggactagctg gatttcctag gctgactaag aatccctaag cctagctggg aaggtgacca 6900 cttccacctt taaacaaggg gcttgcaact tagctcacac ccaaccagat agtaaggaga 6960 gctcactaaa atgctaatta ggcaaaaacg gagataaaga aataaccaat catctgttgc 7020 ctgagagaac agtgagaggg acaatgattg ggatataaac ccaggcattc gagccagcaa 7080 cggcaacccc ctttgggtct cctccttttg tatgggagct ctattttcac tctatttcac 7140 tctattaaat ctttcaactg ca 7162 <210> 255 <211> 1620 <212> DNA <213> Homo sapiens <400> 255 gtcaggcctc tgagcccaaa ccaagccatc gcatcccctg tgacttgcac gtatacaccc 60 agatggcctg aagtaactga agatccacaa aagaagtaaa aatagcctta actgatgaca 120 ttccaccatt gatttgttcc tgtcccaccc taactgatca atgtactttg taatctcccc 180 cacccttaag aaagttcttt gtaattctcc ccacccttga gaatgtactt tgtgagatcc 240 acccctgccc gcaaaacatt gctctcaact tcaccgccta tcccaaaacc tataagaatt 300 aatgataatc catctccctt cgctgactct cttttcggca cccaggtgaa ataaataccc 360 atgttgctca cacaaagcct gtttggtggc ctcttcacac ggacgcacat gaaaccagct 420 acttgggagg ctgaggcagg agaattgctt gaacccggga ggcggaggtt gcggtgaccc 480 gagatcacgc cattgcactc ctgcctgggc aacaagagca aaattccgtc tcagggaaaa 540 aaaaaaaatt agctgggtgt ggtggggcag gcctgtaatc ccagctactc aggaggctga 600 ggcaggagaa tcacttgaac ctgggaggcg gaggttgcag agtcgagatc atgccattgc 660 cctccagcct gggcgactga gtgagactcc atcttaaaaa aaaaaaaaaa aaaagtcttt 720 tattactttt tgagcattta aagagtattt tttggccaga cggtgtggct cacgcctgta 780 atcccagtat tttgggaggc ccaggcgggt ggatcacttg aagcctccag cctggccaac 840 atggcaggag aatgactgga acccgggagg tggatgttgc agtgagccaa gatggtgtca 900 ctgcactcca gcctgggtga cagagagaga ctctgtctca aagacaaaaa gaaaatttgt 960 tcagtatttt cttcaatcag ctttctcaga ctgaatgttc acccttttaa atattcataa 1020 tgttcctgag aatccatttg gctattctgt tttcttcacc cttctccagc cttcccctcc 1080 tcaattcgac ccatttcttc cctacttccc aaaagaaaaa atatctactt tggattaata 1140 taaatcagtt taatctaact tattcaagac ttttttggcc tctacttgga ggttcaagaa 1200 aaggtgtgtc aggcctctga gcccaagcta agccatcata tcccctgtga cctgcacata 1260 cacatccaga tggccggttc ctgccttaac tgatgacatt ccaccacaaa agaagtgaaa 1320 atggcctgtt cctgccttaa ctgatgacat tgtcttgtga aattcctttt cctggctcat 1380 cctgtctcaa aaagctcccc tactgagcac cctgtgaccc ccactctgtc cgccagagaa 1440 caacacccct ttgactgtaa ttttccttta tctacccaaa tcctataaaa cagccgcacc 1500 cttatcttcc ttcgctgact ctctttttgg actcagcccg cctgcaccca ggtgaaataa 1560 acagccatgt tgctcacaca aagcctgttt ggtggtctct tcacacgcac gagcatgaaa 1620 <210> 256 <211> 684 <212> DNA <213> Homo sapiens <400> 256 ttacagtagg tagctggtca ggcatgagca gggcaggaga gggccccttg ccctccccca 60 ggaatatcag gcaaccagca ggtgatggtc agatggttgt taactgtcac tctaaaataa 120 taattggttg caactggcac caggaagggg cagcctccca atagacagaa aaaacctgaa 180 atgcgatcag cagcttccca ataaaatctc aggagtaggg cgagtgggct cacatatgtg 240 cactgaaggc aaaaatggcg gcatttaact ggcctatgac ctaggaacct ttggtaaggg 300 aagaatgcct caagtgagca tgcatacaac tccagtaaac acactgcacg tgtgacccct 360 tcgaagcgct gacaggccac tgcgcacttg gacagcccac ctcaagggaa gaatcagaga 420 agggatgcaa gaccccagaa gcacacaaat gtataaaatc ccaagtcaaa ggtgaaactg 480 cacttgatct ctcaagtcac ccacttgacc ctcttccaag tgtactttac ttccttgcat 540 tcctgctcta aagcttttta ataagctttc actcctgctc taaaacttgc ctcagtctca 600 cactctgcct tctgtcactt agtcgaatta tttcatctga ggaggcaaga actgaggttg 660 ctgcagaccc ttatggattc acca 684 <210> 257 <211> 759 <212> DNA <213> Homo sapiens <400> 257 gagagacagg actagctgga tttcctaggc caactaagaa ttcctaagcc tagctgggga 60 aggagaccgc acccatcttt aaacaccggg cttgtaagtc agctcacacc cgacctatca 120 ggtagtaaag agggctcact aaaataccaa ttaggctaaa agcaggaggt aaagaaatag 180 tcaaatcatc tatcgcctga gagcacagtg ggagggacaa tgattgggat ataaagccag 240 gcatttctag cctgcagtgg caagcccctt tgggtccctt cccgttgcat gggagctctg 300 ttttcactct attaaatctt gcaactgcac actcttccgg tctgtgtttg ttctggctgg 360 agctgagctt ttgctcgccg tccaccactg ctgagcactg ttgtcgcaga cctgtctttg 420 atttccaccc ctccggatcc ggcagggtgt ccacttctga tccagcgagg cgcccactgc 480 tgctcccgat cagggctaaa ggctcgccat tgttccctca tggctaagtg cccaggttat 540 tcctaattga gctgaacact agtcgctggg ttccacagtt cctttccatg acccacagct 600 tctaatagag ctataacact cactgcatgg cccgaggttc cattccttga aatctgtgag 660 gccaagaacc ccaggtcaga gaacaaaagg cttgctccca tcttgggagt agccggccct 720 catcttggga gcgctaagaa caaagacccc cagataaca 759 <210> 258 <211> 76 <212> DNA <213> Homo sapiens <400> 258 ttagagtagg tagctaccca ggcatgagca gagcagggga aggctccccc acaccaggaa 60 tgtcaggtga ccataa 76 <210> 259 <211> 3299 <212> DNA <213> Homo sapiens <400> 259 tttctggtag agacatagga aacgtgtttt atccgtggac ccaaaactcc agcgctggtc 60 atggacttgg gaagacagtc ccaagtcttt ccattttttc ctcagcctcc gccccgccac 120 cctacaatcc ttttatcacc tccccctcct cacacctggt ccagcttaca gtttcgttct 180 gcgactggcc ctcccccacc tgcccagcaa tttcctctta aaaaggtggc tggagctaaa 240 ggcatagtaa aggttaatgc tcctttttct ttatcggacc tctcccaaat cagttagcgt 300 ttaggctctt tttcatcaaa tatgaaaaac ccagcccagt tcatggccca tttagcagca 360 acccttaaga ctctttacag ccctagaccc tgaagggtca gaaggccatc tcattctaat 420 tatgcatttt aacacccagt cagctcctga cattaaataa aactcctaaa attaaattcc 480 ggccctcaaa ccccacaaca ggacttaatt aacctctcct tcaaggtgta caataataaa 540 gtagaggcag ccaagtagca atgtatttct gagttgcaat tccttgcctc cactgtgaga 600 aaaaccccag ccacatctcc agcacacaag aactccaaac acctgaactg cagctgccag 660 gggttcctcc agaacctcct cccccaggaa cttgcttcag gtgccggaaa tctggccact 720 gggcgaagga atgcctgaag cccgggattc ctcctaagcc ttgtcccatc tgtgcgggac 780 cccactggaa atccaactcg cccagcagcc actcccagag cccctggaac tccggcccaa 840 ggctctctga ctgactcctt cccagatctt ctcagcttcg tggctaaaga ctgatgctgc 900 ccgatcacca cagaagcctc ctggaccatc acagatgctt taggtaactc ttaaagtgga 960 gggtaagtcc atccccttct taatcaatac agaggctacc aactccacat taccttcttt 1020 tcaagggcct gtttcctttg cctccataac tgttgtgggt attgaagacc acgcttctaa 1080 aacctcttac actccccaac tctggtgcca acttggacaa tactctttta agcactcctt 1140 tttagttatc cccacctgcc cagctccctg aataggtcaa aacattttaa ctaaattatt 1200 tgcttccctg actattcctg ggctacagcc acacctcatt gttgcctttt cccccagttc 1260 aaagcctcct tcacacatcc tccccttgta tctccccacc ttaaaccgta gtatagtata 1320 cctctactcc ctccttggca accgatcatg cacctcttac catcccatta aaacctagtc 1380 acccttaccc cacttaatgc caatatccca tcccacagca cgctttaaaa ggattaaagc 1440 ctgttatcac tcacctgtta cagcatggac ttttaaagcc tataaactct ccttacaatt 1500 cccccatttt acctgtccaa aaaccagaca agtcttacag gttagttcag gatctgcatc 1560 ttatcaacca aattgttttg cctatctacc ccgtggtgcc aaacccatat actctcctat 1620 cctcaatacc tcccctccac aacccattat tctgttctgg atctcaaaca tgctttcttt 1680 actagtcctt tgcacccttc atcccagcct ctcttcgctt tcacttggac tgaccctaac 1740 acccatcagg ctcagcaaat tacctgggct gtactgccac aaggcttcac agacagcccc 1800 catcacctca gtcaagccag tgttcttaca caagagctgg gaccgcgccc tgtagccttt 1860 ttatccaaac aatttgacct tactgtttta gcctagccct cctgtctgca tgtggcggct 1920 accgctgcct taatactttc agaggctttc aaaatcacaa actatgctca actcactctc 1980 tacagttctc ataacttcca aaatctattt tctttctcac acctgatgca tatactttct 2040 gcccacccca ctacctctca gcaagccaaa ctcattgcct taacttgagc cctcactctt 2100 ccaaaaggac tacacatcaa tatttatact gactctaaat atgccttcca tatcctgcac 2160 caccatgctg ttatataggc aaaaaaaaaa aaaaattcct cactatgcaa gggtcctcca 2220 tcactaatac ctctttaata aaaactcttc tcaaagccgc tttacttctg aaggaagctg 2280 gggtcattca ctgcaagggc catcaaaagg catcagatcc cattgctcag gacaacgctt 2340 atgctgataa ggtagctaaa aaagcagcca tcaaaaagta tcagatccca tcgcccagga 2400 caatgcttat gctaataggg caactaaaaa aagcagccag cgttccaact tctatctcac 2460 agagcagttt ttctccttct catctggcca ctcccaccta ctcccccact gaaacttcca 2520 cctatcaatc tcttcccaca caaggcaagg gtttttggac caaggaaaat atatccttcc 2580 agcctcacag gcccactcta ttctgtcgtc ttttaatacc tgtttttctc ctcttattct 2640 gtttagtttt tcaattcata caaaaccata tccaggccat caccaataat tctatacgac 2700 aaatgctcct tcaaacaacc ccacaatatc acctcttacc acaaaatctt ccttcagctt 2760 aatctctccc actctaggtt cccatgccgc tcctaatccc gccctgagaa acatcgccca 2820 ttatctatcc ataccagccc caaaaatttt cgctacccca acactttacc actatttcgt 2880 tttatttttc ttattaatat aagactacag gaatgttagg cctctgagcc caagctaagc 2940 catcatatgc cctgtgacct gcacatatat atccggatgg cctgaagtaa ctgaagaatc 3000 acaaaagaag tgaaaatagc ctgttcctgc cttaactgat gacattacct tgtgaaattc 3060 cttctcctgg ctcatcctgg ctcgaaagct cccccaatga acaccttgtg acccccacca 3120 aagaacaacc cgctttgact aattttcctt tacctaccca aatcctataa aatggcccca 3180 cccctttctc cctttgctga ctcttttcgg actcagaccg cctgcaccca ggtgattaaa 3240 aagctttatt gctcacacaa agcctgttcc gtggtctctt cacagggaca tgagtgaaa 3299 <210> 260 <211> 662 <212> DNA <213> Homo sapiens <400> 260 ttacagtagg taactagtca gacatgagca gggcaggaga aagctcccac tactcccaca 60 cacaccaaaa atgttacacc actatcacgt gatgatcagg aagttgttag ctgtctctct 120 aaaataataa ttgatcacag ctggtgccag ggaaaggcag actcccaata gatagaaaca 180 ctgaatctgg tgatcagcag cttcccaaca agatctcagg agttgggtga gtgggctgaa 240 gcatgtgcat taagaggcaa atggtagagt ttaactggta tatgactttc taggatcctt 300 ctatcggaaa gagaagaaca ccttaagtga gcatgcatcc aactccaata aacacactgc 360 acatgctcat ttcccaagtg ctagcaggtc actgcacatg tggacagccc aacccaagag 420 aagaatcagt ggagaaggga cacaagaccc cagaagaatg ccaacgtaca aaactccaag 480 tcaaaaggtc aaaccacaca cctgatctcc gaagttgccc agttggcctg cttcttactt 540 cctttcattc ctgctttaaa acttgcctcg gtctctcctt ctgccttatg cccctcagtc 600 aaattctttc ttctgaggag gtgaaaattg aggctgctgc tggcccatat ggatttgcca 660 gt 662 <210> 261 <211> 4163 <212> DNA <213> Homo sapiens <400> 261 cttctccctt agcctgtgtt ctcaagaatt taaaacctct tcatctcaca cctgacctaa 60 aacctaaatg ccttattgtc ttctgcaatg ccgcttgacc ccaatacaaa cttaacaatg 120 gttccaaata gccagaaaat ggcactttca atttttccat cctacaagat ctaaataatt 180 attgccgtaa aatgggtaaa cggtctgtgg tgcctgatat ccaggcattc ttttacacat 240 cagtccctct ctagtctctg ttcccaatgc gattcctccc aaatcctcct tctttccctc 300 ccgcctgtcc cctcagtccc aaccccaagt gtcgccgagt ctttctaatc ttccttttct 360 acagacccat ctgacctctc ccctccttgc caggccaagc taggtcccaa ttcttcctca 420 gcctctgctc ctccacccta taatcctttt atcacctccc ctcctcacac cgggtctggc 480 ttacagtttc gttccgtgac tagccctccc ccacctgccc agcaatttac tcttaagaag 540 gtggctggag ctaaaggcat agtcaaggtt aatgctcctt ttttttttta tcccaaatca 600 gatagcattt aggctctttt tcatcaaata taaaaatcca gcccagttca tggctcattt 660 ggcagcaacc ctgagacgct ttacagccct agaccctaaa aggtcaaaag gccgtcttat 720 tttcaatata cattttatta tccaatctgc gcccgacatt aaataaaact ccaaaaatta 780 aattccagcc ctcaaacccc acaacaggac ttaattaacc tcgccttcga ggtgtacaat 840 aatagaggca gccaagtagc aacatatttc tgagttgcaa ttccttgcct ccactgtgag 900 acaaacccga gccacatctc cagcacacaa gaacttccaa acgcctgaac cgcagcagcc 960 aggcattcct ccagaacctc ctcccccagt agcttgctac aagtgccaga aatctggcca 1020 ccgggccaag gaatgcccac agcccgggat tcctcctaag ccacatccca tctgtgcagg 1080 accccactga aaatcggact gttcaactca cctggcagcc actttcagag cccctggaac 1140 tccggcccaa ctctctctga ctccttccca gatcttctca gcttagcggc tgaagactga 1200 cactgcccaa tcgtctcgga agctcctaga ccaacaccga caccgagctt taggtaactc 1260 tcacagtgaa gggtaagtcc atccccttct taatcaatac gaaggctacc cactccacat 1320 taccttcttt tcaacagcct gtctctcttg cctccataac tgttgtgggt attgaaggcc 1380 aggcttctaa acctcttaaa actccccaac tctggtgcca acttagacaa tactctttta 1440 agcactcctt tttagttatc cccacctgtc cagtttcctt attaggctga gacactttaa 1500 ctaaattatc tgcttccctg actattcctg gactacagcc acatctcatt gccgcacttc 1560 ttcccaatcc aaagcctcct ttgcgtcttc ctctcatatc cccccatctt aacccacaag 1620 tatgggacat ctctactcct tccctggcaa cagatcacat gcccattacc atcccattaa 1680 aacctaatca cccttaccct gctcaacgcc aatatcccat cccacagcac gctttaaaag 1740 gattaaagcc tgttatcact cacctgttac agcatgggct tctaaaacct ataaactctc 1800 cttacagttc ccccatttta cctgtccaaa aaccggacaa gtcttacaga ttagttcagg 1860 atatgcgcct tatcaaccaa attgttttgc ctatcaaccc tgtggtgccc aacctgtaca 1920 ttcttttgtt ctcaatacct ccctccacaa ctcactattc cattcttgat cttaaagatg 1980 cttttttcac aattccactg cacccctcat cccagcctct ctttgctttc agactgacca 2040 tgacacccat cagtcccagc agcttacctg ggctgtgctg ctgcaaggtt tcatggacag 2100 ccctcattac ttcagccaag ctgtttctcg tgatttactt tctttccacc cctctgcttc 2160 tcaccttatt caatatattg atgaccttct tctttgtagc ccctcctttg aatcttctca 2220 acaagacata cttctgctcc ttcagcattt attctccaaa ggatatcagg tatccccctc 2280 caaagctcaa atttcttctc catccattac ctacctcagc ataattctac ataaaaacac 2340 aagtgctctc aaaccccaac cccttctaca aaaaaacaac tcctttcctt cctgggcatg 2400 gttggatact ttcgcctttg gatacctggt tttgccatcc taacaaaacc attatataaa 2460 ctcacgaaag gaaacctagc tgaccccata gatcctaaat cctttcccca ctcctctttg 2520 cattccttga agacagcttt agagactgcc cccgccctag ctctccctga ctcatcccaa 2580 cccttttcat tacacacagc tgaagtgcag agctgtgcat tctaacacaa ggaccaggat 2640 tgtgtcctgt agcctttctg tccaaacaac ttgaccttac tgttttagcc tagccctcat 2700 atctgcgtgc agtggctgcc gctgctttaa tacttttaca ggccctcaaa atcacaaact 2760 atgctcaact cactctctac agctctcata acttccaaaa gctattttct tcctcacacc 2820 tgatacatat actttctgat ccccagctcc ttcagctgta ctcactcttt gttaagtccc 2880 acaattacca tttgcccagg actggcaaat tagctttact caacatgcac cgagtcagaa 2940 aacaaaaata cctcttagtc taagtagaca ttttcactgg ataagtagag gtctttccta 3000 caaggtctga gaaggccacc acagtcattt cttcccttct gtcagacata attcctcggt 3060 ttagcctttt accaccttcc cttctcagaa ttctgacctg tccttggaat gctacaaggt 3120 acagcccatt taagctcctg tatagacact cttttttatt aagccccagt ctcattccag 3180 acaccagacc aacttggact gtgccccaaa aaacttgtca tccctactat cttctgtcta 3240 gtcatactcc tattcactgt tctcaactac tcatatatgc cctgctcttg cttacactgc 3300 cagtttacac tgtttctcca acccatcaca gctgatatct cctggtgcta tccccaaact 3360 gccactctta aatcatcttt gctggcagga ctatgctgaa tctccttagg cactctctaa 3420 ttagatgtcc tgggtcctcc caattcttag atctttaata cctgtttttc tccttattcc 3480 gtttagtttt tcagttcata caaaaccata tcttctaaca gtcccacaat atcacccctt 3540 accacagaat cttccttcag tttaatctct tccactctag gttcccatgc cacccctaat 3600 cctgcttgaa gcagccctga gaaacatcgc ccattatctc tccatagcat cccccaaaat 3660 ttttgccatc ccaacacttt accactattt cgttttgttt ttcttattaa tataagaaga 3720 caggaatgtc aggcctctga gcccaagcta agccatcata tcccctgtga cctgcacgta 3780 cacattcaga tggccagttc ctgccttaac tgatgacatt ccaccacaaa agaagtgaaa 3840 atggcctgtt cctgccttaa ctgatgacat tgtcttgtga aattccttct cctggctcat 3900 cctggctcaa aacctcccct actgagcacc ttgtgacccc tactcctgct cgacagagaa 3960 caacccccct ttgactgtaa ttttccttta cctacccaaa tcttataaaa cggccccacc 4020 cctgtctgtc tttgctgact ctctttgctg actctctttg ctgactctct tttcggactc 4080 agcctgcctg cacccaggtg attaaaagct ttattgctca cacaaagcct gtttggtggt 4140 ctcttcacac ggacacgtat gaa 4163 <210> 262 <211> 962 <212> DNA <213> Homo sapiens <400> 262 gtggggaaaa gaaagagaag tcagactgtt actgtgtcta tgtagaaaga agtagacata 60 agagactcca ttttgctctg tactaagaaa aattcttctg ccttgagatg ctgtttatct 120 gtaaccctac ccccaaccct gtgctccccg aaacaagtgc tgtgtcgact caacgtttaa 180 tggatttagg gctatgcagg atgtgctttg ttaaacaaat gcttgaaggc agcgtgctgt 240 taaaagtcat caccactccc taatctcaag tacccaggga aataaaacac cacggaaggc 300 ggcagggacc tctgcctagg aaagccaggt attgtccgag gtttctcccc atgtgatagt 360 ctgaaatgtg gccttgtggg aagggaaaga cctgatcgtc ccccagcctg acacccataa 420 atggtctgtg ctgaggagga ttagtaaaag aggaaggcct ctttgcagtt gagataagag 480 gaaggcatct gtctcctgct catccctgtc atccctgagc aatggaatgt ctcggtgtaa 540 aaccctatgg tatattccat ctactgagac aggagaaaac caccttagga ctggagttga 600 gacatgctgg tggcaatact gctctttaat gcattgagat gtttatgtat atgcacatca 660 aagcacagca cctttttctt taccttgttt atgatacaga gacatttgtt cacatgtttt 720 cctgctgacc ctctccccac tgttacccta ttgtcctgcc acatccccct ctcagagatg 780 gtagagataa taatcaataa atactgaggg aactcagaga ccatatgctg agcgcggatc 840 ccctgggccc acttttcttt ctctatactt tgtctctgta tctctttctt ttctcagtct 900 ctcgtacccc cgccccccga cgagaaacgc ccacaggtgt ggaggggaag acctcccctt 960 ca 962 <210> 263 <211> 993 <212> DNA <213> Homo sapiens <400> 263 gagctcggct gttggagacg tgagtcttgc tgaagctcct ggccgaataa agcccttcct 60 tctttaactc ggtgtctgag gggttttgcc cgtggcttgt tctgctacat ttcttggttc 120 cctgaccggg aagcgaggtg attaacagac agtcggacgg tcgaggcagc cccttaggtg 180 gcttaggcct gccctgtgga gcatccctat ggggcactcc agccagcttg gccgatgcgg 240 atcctgagag cactcctggg taggcaattg gcctggtgga acgcctcgcc agaggagcac 300 gtggcaggcc cccgtggacg atcaacgcag tggctgaaca ccgggaagga actggcactt 360 ggagtctgga catctgaaac ttggtaagac tagtctttgg aacttgccca ctccatttga 420 gtggaagcgt ggcctgatca cccacggtct gcctgtaccg gcactttggt ttttgttttt 480 gacttgactt ggattgcttg atactttggt tttgtttttg acctggcttg gatttctgga 540 tactctgatt ttggttttga ttctgagttt ggtgtaaact gtaaaagtgt gtgtgtgtgc 600 cctttttact cgttctttgt tttgtggtgt gagcatggtg ttttgtctcg aagaagcatg 660 ggtcaggcac aaagtaagcc caccccacta ggaactatgt tgaaaaattt caaggaagga 720 tttaagggag attatggtgt tactatgaca ccaggaaaac ttagaacttt gtgtgaaata 780 gactggccag cattagaggt gggttggcca tcagaaggaa gcctggacag gtcccttgtt 840 tcaaaggtat ggcacaaggt aacctgtaag ccagggcacc cagatgagtt cccatacata 900 gacccttggt tacagctggt tttagacccc acacccccct caccagtggt tgagagaaca 960 gcagcataag tggctggcag agacaaggaa aga 993 <210> 264 <211> 6158 <212> DNA <213> Homo sapiens <400> 264 gtcaggcctc tgagcccaag ctaagccatc gtatccccag tgacctgcac atatacatcc 60 agatggcctg tttggtgttc tcttcacata gacatgtgag acatttgatg ccaaaaccca 120 ggacgggagg actccttcgg gagaccggtc ccctgtcctc gccctcactc cgtgaggaga 180 tccacctatg acctcgggtc ctcagaccaa ccagaccaag gaacatctca ccaatttcaa 240 atcaggtaag cagtcttttc actcttctct ggcctctctc gctacccttc aatctccctg 300 tcattccaat tccagttctt tttcctctct aatagagaca aaagagacac attttattcg 360 tggacccaaa actccggcgc tagtcatgga cttgggaaga cagccttccc ttgatgttta 420 atcactgcgg ggacacctgc ctgattattc acccacattt cattggtgtc tgatcaccgc 480 agggatgcct gccttggtca ttcacccaca ttcccttggt ggcaagtcaa ttgcggagac 540 gcctgctttg gctgctcacc cacattgcag cccagggctg ctctccaccc ccttctctgt 600 gtctccacct ttctctttaa actaacgtcc ttcactatgg gcaaccttcc gccctccatt 660 cccccttctt ctcccttagc ctgtgttctc aagaacttaa aacctcttca actcgcacct 720 gacctaaaac ttaaatgcct tattttcttc tgcaatactg cttggcccca atacaaactc 780 gacagtagtt ccaagtggcc agagaatggc actttcgatc tgtctatcct ataagatcta 840 gatagttttt gtcgaaaaat gggcaaattc ctacaagatc tagataattt ttgttgaaaa 900 atgggaaatg gtctgaggtg cctgacatcc aggcattctt ttacacattg ctccctccct 960 agtctctgct cccaatgcga cttgtcccaa atctttcttc tttctcctgt ctgttccctc 1020 agtcaccacc ccaagctctg agtcctttga atccttcttt tctacagact catctgacct 1080 ctccccttct ccccaggctg ctcctcgcca ggccaagcca ggtcccaatt cttcctcagc 1140 cgctgctccc caaccctagg atctatctgt cacctcccct cctcacaccc agtctggctt 1200 acagattcgt tctgcaacta gccctcccct acctgcccaa caatttcctc ttaaaaaggt 1260 ggctggagct aaaggcaagt caaggtttct ttatctgacc actcccaaat cagttagcat 1320 ttaggttttt tttcatcaaa tataaaaacc cagcccagtt catggcatgc ttggcaacaa 1380 cccttagaca ctttactgtc ctagatccag gaggaaggct gtcttattct caatatgcac 1440 tttattaccc agtccactcc tgacattgga aaaagctcca aaaattagat tccggccctc 1500 aaaccccata acaggacctt attaacctcg ctttcaaggt gtacaataat agagtagatg 1560 cagccaagta gcaacgtatt tctgagttgc aattacttgc ctccactgtg agagaaaccc 1620 cagccacatc tctagcacac aagaacttca aaacgtctga accgcagcgg ccaggcgttc 1680 ctccaggacc gcctccccca ggatcttgct ctaagtgctg gaaatctggc cactgggcca 1740 aggaatgccc gcagcccagg attcctccta agccgtgtcc catctgtgtg ggaccccatt 1800 ggaaattgga ctgtccaact cgcccggcag ccactcccag agcccctgga actctggccc 1860 aaggctcgct gactgattcc ttcccagatc ttctcagctt agtggctgaa gactgatgct 1920 gcctgatcac ctcagaagcc tcccggacca tcacggacgc tttgggtaac tcttacagtg 1980 gagggtaagt ctgtcccctt cttaatcaat acggaggcta cccactccac attaccctct 2040 tttcaagggc cagtttccct tgcctccata accgttgtag gtattgacag ccaggctgct 2100 aaacctctta aaactcccca actctggtgc caacttggac aacattcttt aatgtactcc 2160 ttttatttat ccccacctgc ccagctctta ttaggatgag acattttaac taaattatct 2220 gcttctctga ctattcctgg gctacagcca cacctcattg ccgccttttc ccccagttca 2280 aagcctccct cacatccttt ccttgtatct ccccacctta atccacaagt ataggacacc 2340 tctactcccg ccttggcaac ggatcatgca ccccttacca tcccattaaa acctaatcac 2400 ccttaccccg ctcaatgcca atatcccatc tcacagcacg ctttaaaagg attaaagcct 2460 gttatcactt gcctgttaca gcatggcctt ttaaagccta taaactctcc ttacaattcc 2520 cccattttag ctgtccaaaa actggacaag tcttacaggt tagttcagga tctgagcctt 2580 atcaaccaaa ttatcttccc tatccacccc gtggtgccaa acccatatac tctcctatcc 2640 tcaatacctc cctccacaac ccattctgtt ctagataaac ctagctgacc ccataaatcc 2700 taactccttt ccccactccc ctttccattc cttaagaagc agccctaaaa gctgttccca 2760 cactagctct ccctaactca tccccaccct tttcattaca cacagccaaa gtacagggct 2820 gtgcggtcag aattcttttt tttttttttg agaagagtct cgccgtgtca cccaggctgg 2880 agtgcagtgg cacgatagtc agtattctta cacaagagcc aggagtgcgc cctgtagcct 2940 ttctgtccaa acaacttgac cttactgttt tcgcatagcc ctcatgtctg catgtggcgg 3000 ctgctgctgc tgctttaata cttttagagg ccctcaaaat cacaaactat gctccactta 3060 ctctctacag ttctcataac tttcaaaatc tattttcctc ctcacacttg aagtatatac 3120 tttctgcccc ccagctcctt caggtatact cagtctttgt tgagtctccc acacttacca 3180 ttgttcctgg cctggacttc aatccagcct cccacattat tccagatacc acacctgacc 3240 cccatgactg tatctctctg atccacccga cattcacttc atttccccat atttctttct 3300 ttcctgttcc ttaccctgat cacacttggt ttattgatgg cagctccacc aggcctaatc 3360 accactcacc agcaaaggca ggctatgcta tagtatcttc cacatctatc attgaggcta 3420 ccactctgcc cccctccact acttctcagc aggctgaact cattgcctta actcgggccc 3480 tctctcttgc aaagggacta cacgtcaata tttatactga ctctaaatat gccttccata 3540 tcctgcacca ccatgctgtt atatgggcag aaagaatgtc ctcactatgc aagggtcctc 3600 catcattaat gcctctctaa taaaaacttc tcaaagctgc tttacttcca aaggaagctg 3660 gagtcattca ctgcaagggc catcaaaagg catcagatcc catcactcag ggcaacactt 3720 atgctgataa ggtagttaaa gaagcagcta gcgtttcaac ttctgtccct catggcccgt 3780 ttttctcctt ctcattggtc actcctattt actcttctac tgaagtttcc acctatcaat 3840 ctcttcccac acaaggcaaa tggttcttgg atcaaggaaa atatctcctt ccagcctcac 3900 aggcccattc tattctgtca tcatttcata acttcttcca tgtaggttac aagctgttag 3960 cccacctctt aaaacttctc atttcctttc catcgtgaat atctatcccc aatcctccac 4020 tcttgactcc ctcttggagt ggatagatga tctttgctga caggacacac tccaacactt 4080 tcaccctgat gaagtcctat tctttacttt tatactcact cttgttctca ttcccattct 4140 tatgccaccc tctacctctc cccagctatc tccaccacac tatcaatctc actcactctc 4200 tcctagccat ctctaatcct tctttaagaa acaattgctg gctttcaaaa gaacaaagct 4260 ggaggcatca tgctacctga cttcaaacta tactacaagg ctacagtaac caaaacagca 4320 tggtactggt accaaaaaag agatatagac caatagaaca gaacagagcc ctcagaaata 4380 atatcacaca tctacaacca tctgatcttt gacaaaccta acaataacaa gaaatgggga 4440 aaggattccc tatttaataa atagttctgg gaaaactggc tagccatatg tagaaagctg 4500 aaactggatc ccttccttac accttctaca aaaattaatt caagatggat taaagactta 4560 actgttagac ctaaaaccat aaaaacccta gaagaaaacc taggcaatac cattcaggac 4620 ataggcatgg gcaaggactt catgtctaaa acaccaaaag caatggcaac agaagccaaa 4680 attgacaaaa gggatctaat taaactaaag agcttctgca cagcaaaaga aactaccatc 4740 agagtgaaca ggcaacctac agaatgggag aaaatttttg aaatctactt atctgacaaa 4800 aggctaatat ccggaatcta caaagaactc aaacaaattt acaagaaaaa aacaaacaac 4860 cccatcaaaa agtgggcaaa ggatatgaac agacacttct caaaagaaga catttaagaa 4920 gccaacagac acatgaaaaa atgctcatca tcactggcca tcagagaaat gcaaatcaaa 4980 accacaataa gataccatct cacaccagtt agaatggcca tcattaaaaa gtcaggaaac 5040 aacaggcgct ggagaggatg tggagaaata ggaacacttt tacactgttg gtgggactgt 5100 aaactggttc aaccattgtg gaagacagtg tggcaattcc tcagggatct agaactagaa 5160 ataccatttg acccagccat cccattactg ggtatatacc caaaggatta taaatcatgc 5220 tgctataaag acacatgcac acgtatgttt atcgtggcac tattcacgat agcaaagact 5280 tagaaccaac ccaaatgtct atcaatgata gactggatta agaaaatgtg gcacatatac 5340 accatggaat actatgcagc cacaaaaaag gatgagttca tgtcctttgt agcaacatgg 5400 atgacgctgg aaaccagcat tctcagcaaa ctatctgagc aaacaaacaa ggacaaaaaa 5460 ccaaacaccg catgttctca ctcataggtg ggaattgaac aatgagaaca cttggacaca 5520 gaaaggggaa catcacacac cggggcctct tgtgcggtgc ggggacgggg gagggatagc 5580 attaggagat acacctaatg taaatgatga gttaatgggt gcagcatacc aacatggcac 5640 atgtatacat atgtaacaaa cctgcacatt gtgcacatgt accctataac ttaaagtata 5700 atttaaaaaa ataagtaaat aaataaataa aaaagaaaca attgctggct ttgcaattct 5760 ctttcctcca aaatcgccga ggcctcaatt tactcattgc tgaaaaagga ggactctgta 5820 tatttttaaa tgcagagtgt tgtttttacc taaatcaatc tggcctggta tatgacaaca 5880 taaaaaaact caaggataga gcccaaaaac ttgccaacca agcaaataac tatgctgaac 5940 ccccttgggc actctcttaa ttggatgtcc tgggtcctcc caattcttag tcctttaata 6000 cctgtttttc tctttctctt attcagacct tgcgtcttct gtttagtttc tcaattcata 6060 caaaaccata tccaggccat caccaataat tctatatgac aaatgctcct tctaacaacc 6120 ccacaatatc agcccttacc ccaaaatctt cagctgaa 6158 <210> 265 <211> 804 <212> DNA <213> Homo sapiens <400> 265 gagagacagg actagctgga ttttctaggc tgactaagaa tccctaagcc tagctgggaa 60 ggtgaccaca tccaccttta aacatggggc ttgcaactta gctcacaccc gaccaatcag 120 gtggtaaaga gagctcacta aaaagctgat taggcaaaaa caggaagtaa agaaatagcc 180 agtcatctat tgactaacag tttagctgga gggacaatga tcgggatata aacccaggca 240 atcgagccgg catcgggtac actcttttgg tcgcctccgt ttgtatggga gctctgtttt 300 cactctacta aatcttgcaa ctgcacgctc ttctggtctg tgtttgtcac ggctggagct 360 gagctttcgc tcgccatctg ccactgctgt ttgccaccct cacagacccg ccaccgactt 420 ccatccctcc agatccggca gggtgtccgc tgtgcttctg atccagcaag gcgcccattg 480 ctgctcccga tcgggctaga ggcttgccat tgttcctgca tggctaagtg cccgggttca 540 tcctaattga gctgaacact cgtcactagg ttccacggtt ctcttccgtg acccacggct 600 tctaatagag ctataacact cactgcatgg cccaagattc cattcctttg aatccctgcg 660 gccaagaatc ccaggtcaga gaacacaagg cttgccacca ttttggaagc agcccgctgc 720 catcttggaa gcagcccacc accatcttgg aagcagccca ccaccgtctg gggagctctg 780 ggagcaagga ccctccggta acat 804 <210> 266 <211> 800 <212> DNA <213> Homo sapiens <400> 266 agacaggact agctgggctt cctaggccga ctaagaattc ctaagcctag ctggggaagg 60 tgaccgcacc cacctttaaa catggggctt gtaactcagc tcacacccga ccaatcaggt 120 agtaaagagg gctcactaaa atacaaatta ggctaaaagc aggaggtaaa gaaatagtca 180 aatcatgtat catctgaacg cacaggggga gggacaataa ttgggatata aaccccaggc 240 attcgagctg ggagtggcaa ccccctttgg gggaagccgc ctttgggtcc cctcccattg 300 tatgggaact ctgttttcac tctattaaat cttgtaactg cacactcttc tggtccatgt 360 ttgttacagc tcgagctgag cttttgctca ccgtccacca ctgctgttgg ccgccatcgc 420 acacctgcca ctgacttcca cccctctgga tccggctggg tgtctgctgc actcctgatc 480 cagcgaggcg cccactgcca ctcccagttg ggctaaaggc tcgccattgt tcctgcacag 540 ctaagtgccc gggttcatcc taatcaagct gaacactagt tgctgggttc tacggttctc 600 ttctgtgacc catggcttct aatcaagctg taacactcac cacataggcc caaggtttca 660 ttccttggaa tctgtgaggc caggaacccc aggtcagaga acaaaaggct tgctgccatc 720 ttgggagcgg ctgccaccat gttgggagcg gcccaccacc atcttgggag ctctaagaac 780 acagacccac ccgtaacatt 800 <210> 267 <211> 5222 <212> DNA <213> Homo sapiens <400> 267 gtcaggcccc cgagcccatg ctaagccatc atatcccctg cgacctgcag gtatacatcc 60 aggtggcctg aagtaattga agaatcacaa aagaagtgaa aatggcctgt tcctgcctta 120 actgatgaca ttaccttgtg aaattccttc tcctggctca tcctggctca aaagctcccc 180 cactgagcac cttgtgtccc ctgcccctgc cagccagaga acaaccccct ttgactataa 240 ttttccacta cctacccaaa tcctataaaa cggccccacc cctatatccc ttcactgact 300 ctcttttcgg actcagccca cctgcaccca ggtgattaaa aagctttatt gctcacacaa 360 agcctgttgg tggtctcttc acacagacat gtgtgaaatt tggtgccgtg actcagatcg 420 ggggacctcc cttgagagat caatcccctg tcctcctgct ctttgctctg tgagaaagat 480 ccacctacaa cctctggtcc tcagaccaat cagcccaaga aacatctcac caattttaaa 540 ttgggtaagc ggccgctttt tactgtcttc tccaagctct cactatccct caacctcttt 600 ctcctttcaa ccttggcgcc acacttcaat ctctcccttc tcttaatttc agttcctttc 660 cttttctggt agagacaaag gagacacatt ttatccgtgg actcaaaact ctggtgctgg 720 tcacggactc atgaagacag tcttcccttg gtgtttaatt attgcgggga cgcctgcttt 780 ggctgctcac ccatattgca gcgcagggct gctcacccaa ccccttctct ctgtgtctct 840 accccttttc cactttcccg gggggcaagc acctcccacc ccttctccac tttcctgggg 900 ggcaagcacc cctcacccct tctctccata tctctaccct ctcttttctc tggactggcc 960 tccttctcta caggcaacct tccaccttct tctcccttag cctgtgttct caagaactga 1020 aaacctcttc aactcacact tgacctaaaa cctaaatgcc ttattttctt ctgcaatgct 1080 gcttaacccc aatacaaact cgacaatggt tccaaatagc cagaaaacag cactttcgat 1140 ttttccatcc tacaagatct agataattct tgtcataaaa tgggcaaatg gtctgaggtg 1200 cctgatgtcc aggcattctt ttacacatca gtccctccct agtctctgtt cccaatgcaa 1260 ctcatcccaa atcttccttc tttccctccc acctgtcccc tcagtcccaa ccccaagtgt 1320 tgctgagtct ttccaatctt cctttttcac agacccatct gacctctccc ctcctcccca 1380 ggctgctcct caccaggcca agccaggtcc caattcttcc tcagcctccg ctcccccacc 1440 ctataatcct tttatcacct cccctcctca cacccagtct ggcttacagt tttttctgtg 1500 actaccctcc cccacctgcc cagcaatttc ctcttaaaaa cgtggctgga gctaaaggca 1560 tagtcaaggt taatgctcct ttttctttat ccgacctctc tcaaatcagt tagtgtttag 1620 gctctttttc atcaaatata aaaactcaac ccagctcatg gctcatttgg cagcaaccct 1680 gagatgcttt acagccctag accctaaaag atcaaaaggc cctcttattc tcaatatacg 1740 ttttattacc caatccactc ctgacattaa ataaaactcc aaaaattaaa ttctggccct 1800 caaaccctgc aacaggactt aattaacctc gccttcaagg tgtacagtaa tagagaagag 1860 ttgcaattac ttgcctccac tgtgagagaa accccagcca catctccagc acacaagaat 1920 ttcaaaacgc ctacgccaca gtgatcaggt gttccttcag gacttcctcc cccaggatct 1980 tgcttcaagt gctggaaatc tggccactgg gccaaggcat gcctgcagcc tgggattcct 2040 tctaagcctt gtcccatctg tgcgggaccc cactggaaat cggactgttc aagtcacctg 2100 gcagcctctc ccagagcccc tggaactctc gcccaaggct ctctgactga ctccttccca 2160 gatcttcttg gcttagaggc cgaagactga cactgcccaa tcacctcgga ggcttcctag 2220 accatcacag atgctttggg taactcttac agtggagggt aagttcaacc tcttcttaat 2280 acagaggcta cccactccac attaccttct tttcaagggc ctgtttccct tgcctccata 2340 actgttgtgg gtattgacgg ccaggcttct aaacctctta aaactcccca actctggtgc 2400 caacttggac aacattcttt tatgcactcc tttttagtta tccccacctg cccagttccc 2460 ttattaagcc aagacatttt aactaaatta tctgcttacc tgactattcc taggctgcag 2520 ccacacctca ttgccaccct tttccccagt tcaaagcctt cttcacatcc tccccttgta 2580 tctctccacc ttaatccaca agtataggac acctctactc cctccttggc aatggatgat 2640 gcacccctta ccatcccatt aaaacctaat cacccttacc ccactcaacg ccaatatccc 2700 atcccacagc acactttaaa aggattaaag cctgttatac cttgcctgtt acagcatggc 2760 cttttaaagc atataaactc tccttacaat tcccctattt tacctgtcca aaaaccagac 2820 aagccttaca ggttagttca ggacctgcac cttatcaatc aaattgtctt gcctatctac 2880 cccatggtgc caaacccata tactctccta tcctcaatac ctccctccgc aacccattat 2940 tctgttctag gaaacctagc tgaccccata gatcctaaat cctttcccca ctcctctttc 3000 tgttccttga agacagcttt agagactgct cccacactag ctctccctga ctcatcccaa 3060 cccttttttc attacacaca accaaagtgc agggttgtgt ggttgaaatt cttacacaag 3120 agctgagacc acgcccagca gcctttttat ccaaacaagt tgaccttact gttttagcct 3180 agccctcatg tctgtgtgtg gcagctgctg ctgccttaat acttttagaa gccctcagaa 3240 tcacaaacta tgctcatctc actctctaca gttctcataa cttccaaaat ctattttctt 3300 catcacacct gatgcatata ctttctgccc ccctccacta cctctcagca agccgaactc 3360 attgccttaa ctcgagccgt cagtcctgca aaaggactac atgtcaatat ttatactgac 3420 tctaaatatg ccttccatat cctgcaccac catgctgtta catgggcaaa aacaggtttc 3480 ctcactatgc aattgtcctc catcattaat tcctctttaa taaaaactct tctcaaagcc 3540 gctttacttc caaaggaagc tggagtcatt cactgcaagg gccatcaaaa gtgtcagatc 3600 ccattgctca gggcaacact tatgctgata aggtagctga aaaagcagct agggttccaa 3660 cttccgtccc tcactacgag tttttctcct tctccttggt cactcccacc tactccccca 3720 ctgaaactgc cgcctatcaa tctcttccca cacaaggcaa atggttctta gaccaaggaa 3780 aatatctcct tccagcctca caggcccatt ctattctgtc atcatttcat atcctcttcc 3840 atgtaggtta caagccacta gcccgcctct tagaatctct catttccttt ccattgtgga 3900 aatctatcct tagggaaatc acttctcagt gttccatctg ctattctact actcctcagg 3960 gattgttcag gtcccctcac cttccctaca catcaagctt ggggatttgc ccctgcccag 4020 gacaggtaaa ttgactttac tcacatgcct cgagtcagga cactaaaata cctcttggtc 4080 tgggtagaca ctttcactgg atgggtagag gcctttccta cagggtctga gaaggccatc 4140 acagtcattt cttccctttt gtcagacata attcctcggt ttggccttcc tacctttata 4200 cagtctgata acggaccggc ctttattagt caaatcaccc aagcagtttc tcaggctctt 4260 ggtattcagt ggaacctttg tacccctcac catcctcaat cttcaggaaa ggtaaaatgg 4320 actaatggtc ttttaaagac atacctcacc aagctcagcc tccaacttaa aaaaaaaaaa 4380 ggagtctgtc aagaatagag cccaaaaact caccaaccaa acaagtaatt atgctgaacc 4440 cccttggata ctctctaatt ggatgtcctg ggtcctccca attcttagtc ctttaatacc 4500 agtttttctc cttctcttat tcagaccttg tgtcttccgt ttagtttctc aattcataca 4560 aaaccgcgtc caggccatca ccaatcattc tatatgacaa atgctccttt taacaacccc 4620 acaatatcgc cccttaccac aaaatcttcc ttcagcttaa tctctcccac tctaggttcc 4680 cataccaccc ctaatcctgc tcaaagcagc cctgagaaac atcgcccatt atctcttcat 4740 accaccccac caaaattttc actgcctcaa cacttcaaca ctattttatg ttatttttct 4800 tattaatata agaagacagg aatgtcaggc ctctgagccc aagctaagcc atcatatccc 4860 ttgtgaccta caggtataca tccagatggc ctgaagtaac tgatgaatca caaaagaagt 4920 gaaaatggcc tgttcctgcc ttaactgata atattacctt gtgaaattcc ttctcctggc 4980 tcatcctggc tcaaaagctc ccccactgag cactttgtgt cccccgcccc tgccagccag 5040 agaacaaccc cctttgactg taattttccg ctacctaccc aaatcctata aaatggcccc 5100 acccctatct cccttcactg actctctttt cgaactcagc ccacctgcac ccaggtgatt 5160 aaaaagcttt attgctcaca caaagcctgt ttggtggtct cttcacatgg atgcgagtga 5220 aa 5222 <210> 268 <211> 6733 <212> DNA <213> Homo sapiens <400> 268 cttcctcctt agcctgtatt cttaaaaacc taaaacccct ttgactaaca cctgacctaa 60 aacctaaatg tcttattttc ttctgtaata ctgcttggcc ccaatacaaa ttcgacaata 120 gttccaagtg gccagagaat ggcacttttg atgtatctat cctacaagac ctagataatt 180 tttgttgaaa attgggcaaa tggtctgagg tgccttacgt caaggcattt tttacacttt 240 gctctttccc tagtctctgc tccagatgcg actcattcca gattttcctc ctttctctcc 300 catctgctct ttaggtctcc acccaagctc agagtcctct gaatcctcct tttccactga 360 cccctctgac ctctctcctc cttccccagc cgctcctcac caggctgaat cgggccccaa 420 ttcttccaca gcctctgctc cccaacccta taacccttct attaactccc ttcctcacac 480 ccaggctggc ttacagtttc gttctgcgac tagttttccc ccacctgccc aacaatttcc 540 tcttagagag gtggctggag ctgaaggcat agtcagggta catgtgcctt tttctctgtc 600 agaccttttc caaatcagcc agcatttagg ctctttctca tcagacacca ctaaatacat 660 acaggaattc caatatctaa ctcagtccta caatttaacc tggagtgact taaatgacac 720 cctgacctct accctcttcc caggtgaatg agaaagagtt tattttctag cccagtccta 780 tgcagacacc tgccggcttc atgagccagg cctccaagag ggcaccagag cagttccccg 840 aggggatccc cattggcaat accagatgga ttccccaggt atagctaggt gagattacat 900 ggtctcctac ctagtcaagg ggctcaaaaa ggcagcatac aaagctttta attatgacaa 960 gttaaaggaa actacccaag gtaaagatga aaacccagcc cagttcatgg cctgcttagc 1020 agctaccctt agacgcttta cagccctaga cccagagggt ccagaagaat tccttatcct 1080 taatatgcat tttatcaccc aatccactcc tgacattaga aaaaaactcc aaaagttgga 1140 ttctggccct caaaccccac aacaggattt aataaacctt gccttcaagg tgttcaataa 1200 cagagaagaa gccgccaagc agcaatgtat ctctgagtta cagccacttg cctccgctgt 1260 aagacaaccc acaaccacgt ctccagcata caaaaccttc agaacatcca agccacagct 1320 cccaggggct cctttaaaac ctcctcgtgg accttgcttc aaatgccaaa agtctggcca 1380 ctgggcctca gaatgcccac agcctgggat tcctcctaag ccatgcgcta tctgcacagg 1440 cccccactgg aagtcggatg tccaactcac atcactgcag ctcctaaagc tcctggagct 1500 caaatccaat gttccttggc tgactccttc ccagatctcc tcagcttagc ggctgaagac 1560 tgacactgcc tgatcgcctc agaagccgct ggaccatcac cgatgttgag ctttgggtaa 1620 ctcttacagt ggagggtaag tccatcccct gtttaatcaa tacaggggat acccactcca 1680 cattaccttc ttttcaaggg cccatttccc ttgcccccat aacaactgtt gtgggtattg 1740 atggccaggc ttctagaccc cttaaaactc cccaactctg gtgccaactt ggacaacatt 1800 attttatgca ctgcttttta gttatcacca cctgcccagt tcccttgtta ggctgagcca 1860 ttttaactaa attatctgct tccctgacta ttcctggact acagccacac ctcattgctg 1920 cccttttgcc caatccaatg cctcttttga atcttcctct cgtgtctccc taccttaatc 1980 cacaagtata ggacacctct actccctcct tggtgaccga tcaggcaccc cttatcccat 2040 taaaacctaa tcacccttac cctgctcaac accagcaccc catcccacaa caggctttaa 2100 gaggagtaaa gcctgttatc actcacctgt tacagcatgg ccttttaaag cctacaaatt 2160 ctccttacaa ctcccttatc ctacctgtcc agaaactgga caaatcttac aggctggttc 2220 aggatcttca ccttattaac caaattgtct tacctatcca tcctgtggtg ctaaacccgt 2280 atactctcct atcttcaata cctccctcca taactcatta ttccatcctc gatctcaaag 2340 aagctctctc cactattcct ttgcacccct catcccaacc tcctctcgct ttcacatgga 2400 ctgaccctga cacccacaaa tctcagcaac tcacctggac tgtactgcca caaggcttca 2460 gagacagccc ccattacttt agtcaagctc tttctcatga tctactttct ttccgtccat 2520 ctgtttctca ccttattcaa tatatgggcg accttctcct ctgcagcccc tcttatgaat 2580 cttcctaaca ggataccctc ctgctccttc aacatctatt ctgaaagggg tattgcgtat 2640 ccccttctaa agcccaaatt tcttccccat ccattacgta tctcggcata gtccttcatc 2700 aaaacacatg tgctctccct gctaatcatg tccagctaat ctccaaaacc ctaacccctt 2760 ctacaaagcc acaactcatt tccttcctag gcatggttgg atactttcgc ctttggatac 2820 caggttttgc catcctaact aaaccactat ataaactcac aaaggaaaac ctgactgacc 2880 ccatagaccc taagtccttt ccccactctt cttttcattc cttaaagatg tcctagaaac 2940 agctcccaca ttaacactcc ctaactcgtc ccaatccttc ttcttacata cggctgaaat 3000 acatggctgt gcggtcggag ttcttacaca ggaaccaggc ccacgacctg tagccttcct 3060 atccaaacaa cttaacttca cagttctaga ctggccctca tgtctacgtg aggcggcagc 3120 caccacttca atacttctag aggtcctcaa ggtcacaaac catgtcccac ttactcttta 3180 catctctcat aactttcaaa atctattttc ctcctcacac ttggcgcata tactttctgc 3240 cccccgactc ctccaatttt actcactatt cattgaaact ccctacatca ccatgctgtt 3300 atatgggcag aaagaggttt tgtcactaca caagtgtcct ccatcatcaa cgcttcctta 3360 ataaaaatcc tccttaaggc tgctctactg cctaaggaag ccagagtcat tcactgcaag 3420 gggcctcaga ggtcaccaaa tcccattact caaggcaatg cttatgctga taatgcagca 3480 aaagaagcag ctagtattcc cacatctgtc cctcacggcc agtttttttc cttcactccc 3540 acatattctc ccactgaaac tattatctat taatcccttc ctactcaagg caaatggttc 3600 ttggatcaag gaaaatacct ccttcctgcc tcacaggctc attctatctt atcttccttt 3660 cataacctct ttcatgtggg ttacaagcca atggcccatc tcttagaacc tctcatttct 3720 tttccatcat ggaaatccat cctcaaggaa attacttctc agcattccat ctgctactct 3780 accacccctc agggatatct caggcctcct tcctttcctg tacatcaagc ttgaggattt 3840 gcccccaccc aagactggca ggttgacttt atccatatgc accgagtcaa aacactaaga 3900 taccgtttgg tctgggtaga tacattcact ggatgggtag aggcctttcc cacagggtct 3960 gagaaggcca ctgcagtcat ttcttccctc ctgtcatatt ggccttccca cctctatata 4020 gtgcaataac ggaccagcct tcattaggtc actcaagcag tctcccaggc ccttggcatc 4080 cagtggaacc ctcatgcccc ttaccgtcct caatcttcag gaaaggtaga aagaactaat 4140 ggtcttttaa aaacacacct caccaagctc agcctacaac ttaaaaaaga ctgcacagta 4200 cttttaccgt ttgccctcct tagaattaga acctgtcctt gagaagctat agggtatagt 4260 ccatttgaac ttttatatgg atgtaccttc ttgttgggcc ccaaccttgt gccagacacc 4320 agccctctag gcgactatct tccagtcctc cagcaggcta gacaggaaat ttgccaggct 4380 gctaatcttc tcttgcctac tccagattcc cagcgataca aagatacccc tgctggatta 4440 tcagttcttg ttaagaatct gacccctcaa actctacaac cttgatggac tggaccctac 4500 ttagtcatct atagtacccc aactgccatg cacctgcagg accctcccca ttgggttcac 4560 cattccagaa taaagctgtg tccatcggac agccagcctg atctctcctc ttcctcctgg 4620 aagtcacaag tactctcccc tacttccctt aaactcacct gcatttctga ataacagtaa 4680 taacccttat gagcctaata catcccttca ttctattagg tctattcatc cttaccctac 4740 tttttgcaat ggggctttac gcagtcacct gcactacttg gactgcaccc caaaaacttg 4800 tcatccctac tatcttctgt ctagtcatac acctattcac cattctcaac tactcataaa 4860 tgccttgccc ttgtttacac tgccggttta cacttttcct ccagaccatc ataactgata 4920 tctcccggtt ttacctcaaa ccgccaccct taactctctc ttggagtgga tagaagatct 4980 tcaatggcaa gatacactcc aattcttcta tcctgatgaa gtgctttttt ttttactttt 5040 ctactcactc ttatccttac ctccattctc cagtcactct ctacctctct ctagttacct 5100 ccagcatact atcagtctca cccactctct cctcactgcc tccaatccct ctctagcaaa 5160 gaattgttgg ctatgcattt ccctttcttc ctgctcttac acagccatcc ccgctctgta 5220 ggctgactgg gctacctctc ctgtctgcct gcacctccga acctccttta atagccctca 5280 tctttaccca cctgaggaaa ttctttactt tctagacaga tttggtgaga actccccaga 5340 catttcgcac caacaagctg ccacatttct ccgcatctag ttacagcacc tttttcctta 5400 tgtcaattcc accctcaccc cccatatttg gacccctcag cacacaaaca accatccctg 5460 tggctgctcc tttatgcatc tcccgacaac accctactgg aatcacttta ggcaaccttc 5520 caccatccaa atgttccttt actcttcatc ttcagaaccc agccacacac attaccaaac 5580 agatgggagg attccaactt cgcattaccg ataagccctc tatcattact gacaaactaa 5640 aaaacattgg cagtcactat tgtttaggaa gacacctacc ctgcatctca ctccatcctt 5700 cgctaccctc catctgctca tctgactctc ctcctggccc ctcctcttgt ttgcttatac 5760 ccagccccat gaatagtagt gaaaggttac tcatagacac tatgttcttt ctcatacacc 5820 ataagaaccg aacctctccc tctatgcagt tgcaccatca atccccatta caacctctaa 5880 tggctgcttc ccttgctgga tctctaggat tttgggtgca ggactcctct ttcagtacac 5940 cctctcacct tttcacttta tatttccggt tctgcctgac actaggtctc ttctttttat 6000 gtggctcttc cacctacatg tgcctacctg ccaactggat ggacacacgt actctagtct 6060 tccttacccc caaaatccag tttgcagatg ggaatgaaaa actgcctgtc cccctcatga 6120 catcaacaca acaaaaaaaa gtcatcccac taatcccttt acttgtgggt ctaggacttt 6180 ctgcctccac tattgcactt ggaactggaa tagcaggcat ttcaatctct gtcacaacat 6240 tttgcagcct ctctaatgac ttctctgcta gcattacaga tatgtcacag acgttatctg 6300 tcctccaagc ccaggttgac tctttagctt cagttatcct ccagaactgc cggggcctcg 6360 atttacttgc tgctgaaaaa ggaggactct gtatatttct taatgaagag tgttgttttt 6420 acttaaatca atctggcctg gtatatgata acatcaaaaa actcaaagac agctcaaaaa 6480 ctcgctaatc aggcaactaa tcatgctgga tccacctggc cactctctaa ctgggtatcc 6540 tggcgtcttc caatcgttag tcctctaata tctatcttcc tcctcctttt atttaggcct 6600 tgtgtcttcc caattaaact ctcaattcct atgaaactgc atccaggcta tcactaatca 6660 ctctatatga caaatgctgc tttgaacagc cccacagtat caccccttac cccaaaatct 6720 tacttcaatc taa 6733 <210> 269 <211> 160 <212> DNA <213> Homo sapiens <400> 269 tgaaatgtgt ccaaaatgta aaaaaggaaa acattgagct agtcagtgtc actctaagtt 60 tgataaagat gggaacccaa tttcaggaaa tgccatgagg tgccagccca tcccggcccc 120 cactccagac tggggcattt ccagctcagg ccattccttc 160 <210> 270 <211> 5398 <212> DNA <213> Homo sapiens <400> 270 ccctttgggt cccctcccat tgtatgcgag ctctgttttc acttattaaa tcttgcagct 60 gcacactttt ctggtccgtg tttgttcctg ctcgagctga gctttcactc actgtccacc 120 actgctgttt gccgccgtcg catacccgcc attgacttcc acccctccgg atctggcagg 180 gtgtctgctg catttctgat ccagcgaggc acccattgcc gcttccgttt gggctagagg 240 cttgccattg ttcctgcacg gctaagtgca ggaatttgtc ctaatcaagc tgaacactag 300 tcactgggtt ccacggttct cttctgtgac ccacggcttc taatagagct ataacattaa 360 ccgcatggac caaggttcca ttccttggat tccgtgaggc caagaacccc agatcagaga 420 acaaaaggct tgcttccatc ttgggagtgg ccgccaccat cttgtgagct ctaagaacaa 480 agacccacct gtaacatttg gtggcaaccg tatggtgatt ctccaaagcg gtgagtaata 540 ttggaccact ttggcttgct attctgtcct atccttcctt agagttggag gaaaatactg 600 ggcacctgtt ggccagttaa aaacgattag tgtggctgcc ggacttaaga ctcaggtgtg 660 aggcttcctg gggaaaggct ttctaacaac ccccaaccct tctgggttga gagcattggt 720 ctgcctggaa gcagcttcca ctttcacagt ttcctggggg aagccaaggg ctgactagag 780 gcagaaagct gttgtcccga actcctggca ttggctggtt gagatcatgg cgcagccaga 840 agtctctact catcagttgc ccatgtgtgc acccctacct ctccttctga cccatacctc 900 ctgggtcctg accacaactt tcttgaaagt gtagccccca agttctcctt acctctgatt 960 ctactttctc tgatccctga ctcctagata ctaatgcttc agactttcac ttcctctcct 1020 aagtattaga gcaagtggta tcttcaaagg gatccaagga agctctatgt ggtgtcctta 1080 ggcaactagg ctatgaaccc agggagtctt gtccctggtg cccctcccaa tttaggtata 1140 tagctcttga catggacagt tatgtgggac ccattcctca ccacccttgc cagggcccca 1200 agttctattc tgagctgtgg ccccaagttt gtaaatggct atgaggattg ctctcccatt 1260 gtgtaagatg ctctcctccc ccaattgcta ccctgcttac ccctctgcaa tacaatctcc 1320 aagccttggc ttcttggcca ggaccttaga actgataacc cagtacttta acaaacggaa 1380 ctaggtctat gacaacatga tagatcagga tgaaagtgaa ttgagtaaat taaagggaga 1440 tgcatattcc tatagtggca aatgggggca atgagcgaac atccttctgc tgtgttccca 1500 aaatccatct acaaaaagag agagaggaaa gagagaaaga aaagagggaa aaagggaaaa 1560 gagagagggg aaagagagag agaaaaagag agagaggaaa gaaagaggaa aagagggagt 1620 caaagaaaga ggagagagag gggagagaga ggggaaagag agagagagga aagagagaga 1680 ggggaaagag aaaggcagag acagaaagag agagataaaa gtagtaaaga aaaaaacagt 1740 gcaccctatt cctttaaaag ccagggtaaa tttaaaacct acaattgata attgaacatc 1800 ttctctgtga ccctgtaaca ctccaatacc accttgttgt cagtataaac aagggcatag 1860 cccaaaagca ctgaggacac tgacaatcag tagccttcct atcaaaaatc cttaacccag 1920 taacccacgg atggcccaaa tgcatttaat ctgtagaggc aactgctttg ctagcagaag 1980 aaagtagaaa aataactttt agaggaaacc tcattgtgag cacacctcag aactatccta 2040 agtaaaaaaa gcagaaaggt agcttactaa ctcaaaaatc ttaaagtatg gggctattcc 2100 gttagaaaaa gatgacttaa cattaaccac tgaaaatttc cttaacctgg cagatttcct 2160 aacaggggat ttaaatctta actaccatac aaaagtccga ccagacctag gagaaactcc 2220 cttcaggaca ggatgataga tggttcctcc tgggtgattg aaaaaaaaaa caaaaaacca 2280 caatgggtat tcagtaactg atagggaaac tcttatagaa gcagttagga aaattgccta 2340 ataattggtc tgttcaaagg tacaagctgt ttgcactcag ccaagcctta aaatacttac 2400 agaatcaaga aactctatct caatcctgac tcaaaaggtt acctacaccc cctctgaaac 2460 aaatttgcat aagaattgtt gtttatggga atgcatcttg atggggcagc tgggttgtta 2520 tgaaatactc aggaacccag cccagctcta gaactcaccc ctgagcacaa aggcaatgtt 2580 aggcatggtg gtaaaggacc actagaatcc agcagcccag acccctttct ttgtggtcaa 2640 gaaaggcggg aaaacaggtg taggactgct acatcggtga gcgtaactaa tccgataagc 2700 agaggtccat gggtggttat gcaccctgga aaggaataag cattaggacc atcaaggatg 2760 ctctatgact aatgctcatt ggaaaatgac tagggctgct ggcatccata tgttcttttt 2820 tcagatggga aacgttcccc gcaaggaaaa actccactaa gatgtattct ggagaatttg 2880 gcccagtcag agtgtatgta ccttttaccc tgtcagactt gaagcaaact aaaatagacc 2940 taggtaaatt ctcagataac tctgatgact atattggtgt tttacaaggg ttaggacaat 3000 cctttgatct gacatggaga gatacaatgt tactgctaga tcagacacta accccaaatg 3060 agagaagtgc caccataact gtagcccaag agtttggcga tctctggtat ctcagtcagg 3120 tcaataatag gatgacaaca gaagaaggag agcaattcct cacaagccag caggcagttc 3180 ctagtgtaga ctctcactgc gacacagaat cagaacatgg atattggtgc cacagacatt 3240 tgctaacttg cgtgctagaa ggactaagga aaactaggaa gaagcctata aattattcaa 3300 tgatgtccac tgtaacacag ggaaaggaag aaaatcctac tgcttttctg gagagactaa 3360 gggaggcatt gaggaagcgt atctctctgt cacctgactc tactgaaggt caactaatct 3420 taaaggataa gtttatcact cagtcagttg cagacattag aaaaaacttc aaaagtccac 3480 cttaggcccg cagcaaaact tagaaaccct attgaacttg gcaaccttgg ttttatataa 3540 tagagatcag gaggagcagg cagaacggga caaatgggat aaaagaaaaa aggccaccgc 3600 tttagtcatg gccctcaggc aagtggactt tggaggctct ggaaaaggga aaggctgggc 3660 aaatcaaacg cttaataggg cttgcttcca gtgcggtcta caaggacact ttaaaaaaga 3720 ttgtctgaat agaaataagc cgccccctcg tccatgcccc ttatgttaag ggaatcactg 3780 gaaggcccac tgccccaggg gacgaaggtc ctctgagtca gaagccacta actagatgat 3840 ccagcagcag gactgagggt gcccggggca agcgccagcc catgccatca ccctcacaga 3900 gccccgggta tgcttgacca ttgagggcca agacgctaac tgtctcctgg acactggcgc 3960 agccttctca gtcttactct cttgttccag acaactgtcc tccagatctg tcactatccg 4020 aggggtccta ggacaggcag tcattagata cttctcccag ccactacttg tgactgggga 4080 actttactct tttcttatgc ctttctaatt atgcctgaaa gccccactcc tttgttaggg 4140 agagacatcc tagcaaaacc aggggccatt atacactaga attaggagaa ggaaaaaggg 4200 taaatatata tacagactct aagtatgctt acctagtcct ccatgcccac gcagcaatat 4260 ggagagaaag ggaattccta acttctgagg gaactcctat caaacatcag gaagccatta 4320 agagattgtt attggctgta cagaaacctg aagagatggg gtcatcagaa aggaaaacaa 4380 agggaaatag aagggaaccg gcaagtggat attgaagcca aaagagccac aaggcgggac 4440 cctctgttag aaaagcttat agaaagaccc ctagtatggg gtaatcccct ccaggaaacc 4500 aagccccagt actcagccga agaaatagaa tggggaccct cacaaggaca tagtttcctc 4560 ccctcaggat ggctagccac caaagaagga aaaatacttt tgcctgcagc taaccagtgg 4620 aaattactta aaatccttca ccaaaccttt tactcagaca ttgatagcac ccatcagatg 4680 gtcaaatcat ttactgggcc aagcctttgc aaaactatca agggcctgtg aagtgtgcca 4740 aagaaataat cccctacact tcaggccata catttcaatc cctgtatctt taacctcctt 4800 gttaagtttg tctcttccag aatcaaactg taaaactaca aatcgttctt caaatggagc 4860 cccagatgca gcccatgact aagatctacc gtggactgct ggactggcct gctagcccat 4920 gctccaatgt tcatgacatc gaaggcacct ctccagagga aatctcaact gcatgacccc 4980 tattacaccc caattcagca ggaagcagtt agagcggtcg tcaggcaacc tccccaacag 5040 tacttgggtt ttcctgttga gaaggggaac tgagagacag gactagctgg atttcctagg 5100 tcgactaaga attcctaagc ctagctgggg aaggtgacag cacctacctt taaacatggg 5160 gcttgtaact cagctcacac ctgaccaatc aggtagtaaa gagggctcac taaaatacca 5220 gttagactaa aagcaggagg taaagaaata gtcaaatcat gtatcgcctg agagcacagg 5280 gggagggaca atgatcggga tataaaccca agcatttgaa ctggcggtgg aaaccccctt 5340 tgggtctcct cccattgtat gggagctctg ttttcactct atgaaatctt gcagctgc 5398 <210> 271 <211> 930 <212> DNA <213> Homo sapiens <400> 271 ggggaaaaga aagagagatc agattgttaa tgtgtctgta tagaaagtag acataagaga 60 ctccatttta atctgtaacc ctacccccaa ccctgtgttc cctgagacat gtgctgtgtc 120 aactcagggt taaatggatt aagggctgtg caagatgtgc tttgttaaac agatgcttga 180 aggcagcatg ctcattaaga gtcatcacca ctctctaatc tcaagtaccc agggacacaa 240 acactgcgga aggctgcagg gacctctgcc taggaaagcc aggtattgtc caaggtttct 300 ccccatgtga cagtctgaaa tatggcctct tgggaaggga aagacctgac agtcccccag 360 cccgacaccc ataaagggtc tgtgctgagg aggattagta aaagaggaaa gaacgcctct 420 ttgcggttga gacaagagga aggcatctgt ctcctgcctg tccctgggca atggaatgtc 480 tcggtgtaaa acccgattgt atattccatc tactgagata ggggaaaacc gccttagggc 540 tggaggtggc acattcgggc agcaatactg ctctttaagg cattgagatg tttatgtgta 600 tacatatcta aagcacagca cttaattctt taccttgttt atgatgcaga gacctttgtt 660 cacgtgttta cctgctgacc ttctctccac tattatccta tgatcctgcc acatccgcct 720 ctccgagaaa cacccaataa tgatcaataa atactaaggg aactcagagg ccaataaata 780 caaagggatc ctccgtatgc tgaacgccgg tcccctgggc cccctttttt ctttctatat 840 actttgtgtc tgtgtctctt tcttttccaa gtctctcgtt ccacctaacg agaaacaccc 900 acaggtgtgg aggggcaacc caccccttca 930 <210> 272 <211> 454 <212> DNA <213> Homo sapiens <400> 272 gtcaggcctc tgagcccaag ccaagccatc gcatcccctg tgacttgcac gtatacgacc 60 agatggcctg aagtaactga aaaatcacaa cagaaatgaa tatgccctgc cccaccttaa 120 ctgatgacat tccaccacaa aagaagtgta aatggccagt ccttgcctta agtgatgaga 180 ttaccttgtg aaattccttc tcccggctca tcctggctca aaaagcaccc ccactgagca 240 ccttgcgacc cccactcctg cccgccagag aacaaacccc ctttgactgt aattttcctt 300 tacctaccca aatcctataa aacggcccca cccttatctc ccttcgctga ctctcttttc 360 ggactcagcc tgcccgcctg cacccaggtg attaaaagct ttattgctca cacagagcct 420 gtttggtggt ctcttcacag ggacgcgcat gaaa 454 <210> 273 <211> 686 <212> DNA <213> Homo sapiens <400> 273 gtcagacctc tgagcccaag ctaagccatc atatcccctg tgacctgcac gtatacatcc 60 agatggcctg ttcttgcctt aactgatgac attccaccac aaaagaagtg aaaatggcct 120 gttcctgcct taactgatga cattaacctt gtgaaattcc ttcgactggc tcatcttggc 180 tcaaaaactc ccccactgag caccttgtga ccccccaccc ctgccagaca gagaacaacc 240 ccctttgact gtaattttcc tttacctacc gaaatcctat aaaagggccc cacccctatc 300 tcccttcact gactcctttt ttggactcag cctgcctgca ctcaggtgaa ataaacagtc 360 ttgttgctca cacaaagcct gtttggtggt ctcttcacat ggacttcagt gaaatttggt 420 gccgtgactc ggatcggggg acctcccttg ggagatcaat ctcctgtcct cctgctcttt 480 gctccatgag aaagatccac ctacgatctc tggtcctcag atcaaccaga ccaaggaaca 540 tctcaccaat tttaaatcgg gtaagcggcc tctttttact ctcttctcca acctctctcc 600 ctatccctcc acctctttct cctttcaatc ttggtgccac acttcaatct ctcccttctc 660 ttaatttcag ttcctttcct tttctg 686 <210> 274 <211> 5673 <212> DNA <213> Homo sapiens <400> 274 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tggcctgcac gtatatatcc 60 agatggcctg aagtaactga agaatcacaa aagaagtgaa aatggcctgt tcctgactta 120 actgatgaca ttaccttgtg aaattccttc tcctggctcg tcctggctca aaagctcccc 180 cactgagcac cttgtgtccc ccacccctgc ccaccagaga acaaccccct ttgactgtaa 240 ttttccatta cctacccaaa tcctataaaa cggccccacc cctatctccc ttcgatgact 300 gtctttttgg actcagacct cctgcaccca ggtgaaataa acagcctcgt tgctcacaca 360 aagcctgttt ggtggtctct tcacatggac accagtgaaa tttggttccg tgactcggat 420 caggggacct ctcttgggag atcaatcccc tgtcctcctg ctctttgctc tgtgagaaag 480 atccacctat gacctctggt cctcagacta accagcccaa ggaacatctc accaatttta 540 aatctggtaa gtggcctctc ttcactctct tctccaacct ctctcactat ccctcaacct 600 ctttcttctt tcaatcttgg caccacactt caatctctcc cttctcttaa tttcagttcc 660 tttccttttc tcgtagagac agagatgatg cattttatct gtggacctga agctccagca 720 ccagtcacgg acttgggttt aatcatgtgg ggatgcctgc ctgattattt acccacattt 780 cattggtgtc tgatcaccac ggggatgctt gccttggtca ttcacccaca ttccttggtg 840 gcaagtgaat tgcgggggcg cctgctttgg ctgctcaccc acattgcagc ccagggctgc 900 tcacccaacc ccttctctcc atgtacccac cccttctcca ctttcctggg gggcaagcac 960 ctcccacccc ttttacactt ttctgggggg caagcacccc ccactccttc tctctgtgtc 1020 tctactctct cttttctctg ggcttgcctc cttcattatg gacaaccttc caccttccat 1080 tcctccttct tctcccttag cctgcattct caaaaactta aaacctcttc aactctcagc 1140 tgacctaaaa tctaagcatc ttattttctt ctgcaacact gcttgacccc aatacaaact 1200 cgacagtggt tccaaatagc cagaaaatgg cacttttgat ttttccatcc tacaaaatct 1260 agataattct tgtcgtaaaa tgggcaaacg gtctgaggtc cctgatatcc aggcattctt 1320 ttacacattg gtccctccct agtctctgtt cccaatgcaa ctcatcccaa atcttgcttc 1380 tttccctcct gcctgttctc tcagtcccaa ccctaatcat cactgggtct ttccaatctt 1440 ccttttctac agactcatct gacctgtccc ctcctcacca ggctgctcct tgccaggccg 1500 agctaggtcc caattcttcc tcagcctcta ttccctgacc ctataattct tttttcacct 1560 cccctcctca cacccggtct ggtttacagt ttcgttccac aactagccct cccccacctg 1620 cccagcaatt tcctcttaaa aaggtggctg gagctaaagg cgtagtcaag gttaatgttc 1680 ctttttcttt atctgacctc tcccaaatca gttagcattt aggctctttt tcatcaaata 1740 taaaaaccca gcccggtcca tggccctttt ggcagcaacc ctgagactgt ttacagccct 1800 agaccctgaa gggtcagaag gccatctcat tctaaatatg cattttatta cccagtcagc 1860 tcctgacatt agaataaagc tccaaaaatt aaattccagc cctcaaaccc cacaacagga 1920 cttaattaac cttgccttca aggtgtacaa taatagagta gaggcagcca agtagcaatg 1980 tatttctgaa ttgcaattcc ttgcctccac tgtgagacaa accccagaca catctccagc 2040 acacaagaac tccaaatgcc tgaaccgcag ctgccagggg ttcctccaga acctcctccc 2100 ccaggagctt gctacaagtg ccagcaatct ggcctctggg ccaaggaatg cctgcagcct 2160 gggcttcctc ctagccatgt cccatctgtg caggacccca ctggaaattg gactgtccaa 2220 cttgccccgc agccagtcct agggccccta aagctctagc ccaaggctct ctgactgact 2280 cctccccaga tctgctcagc ttagcagctg aagactgatg ctgaccaatc acctcggaag 2340 ccccctggac catgatggac actgagcttt gggtaactct tatggtggag ggtaagtccg 2400 tccccttctt aatcaatacg gaggctaccc actccacatt accttctttc caagggccta 2460 tttcccttgc ctccataact gttgtgggta ttgatggccc agcttcaaaa ccccttaaaa 2520 ttcccccact ctggtgccaa cttggacaac attcttttat gcactctttt ttcagttatc 2580 cccacctgcc cagttccctt attaggccaa gatattttaa ccaaattatc tgcttccctg 2640 actattcctg gactacagcc acatctcatt gccgtccttc ttcccaaccc aaagcctcct 2700 ttgcgtcttc ctcttgtatc ccccaacctt aacccacaaa tatggaatac ctctactccc 2760 tccctggcaa ccgatcacat gcccattact atcccattaa aatctaatca cccttaccct 2820 actcagcgcc aatatctcat cctgcagcat gctttaaaag gattaaagcc tgttatcact 2880 cacctgctac agcatgggct tctaaaacct ataaattctg cttacaatac ccccatctta 2940 cctgtcctaa aaccagacaa gccttacagg ttagttcagg atctgcgcct tatcaaccaa 3000 attgttttgc ctatccaccc cgaggtgcca aacccatata ctctcctatc cttaatacct 3060 ccctccacaa cccattattc tgttctagat aaacctagct gaccccataa atcctaaatc 3120 ctttccccac tcccctttcc attccttaaa aaacagccct aaaagctgct cctatgctgg 3180 ctctccgtaa ctcttcactc ccttttcatt acatacagct gaagtgcagg gctgtgtggt 3240 cggaattctt atacaaggac caggactgcg ccctgtagcc cttttatcca aacaacttga 3300 ccttactgtt ttagcctagc cctcatgtct gtgtgtggtg gctaccactg tgttaatgct 3360 tttagaggcc ctcaaaatcc caaactatgc tcagctcact ctctacagtt ctcataattt 3420 ccaaaatcta ttttcttcct ctcacctggc tccttcagct atactcactc ttagttgagt 3480 ctcccacaat taccattgtt cctggcctgg acttcaatct ggcctcccac attattcctg 3540 ataccacacc tgacccccat gactgtatct ctctgatcca cctgacattc accccatttc 3600 cccatatttc cttctttcct gttcctcacc ctgatcacac ttggtttatc aatggcagtt 3660 ccaccaggct taatcgccac acaccagcaa aggcaggcta tgctatagta tcttccacat 3720 ctatcattga ggctaccgct ctgcccccca ctatctctca gcaagctgaa ctcattgcct 3780 gaacttgggc cctcactctt gcaaagggac tacaaatcaa tattaatact gactctaaat 3840 atgccttcca tatcctgcac caccatatgg gcagaaagaa atttctcact atgcaagggt 3900 cctccatcat taatgcctct ttaaaaaaaa aacatttctc aaagctgctt tacttccaaa 3960 ggaagctgga gtcattcact gcaaaggcca tcaaaaggca ccagatccca tcgctcagga 4020 caatgcttat gctcataagg tagctaaaaa agcagccatc aaaaggcatc agatcccatc 4080 actcaggaca atgcttatgc tgataaggta gctaaaaaag cagctagcat tccaacttct 4140 atccctcacg gcagtttttc tccttctcat ctgaccactc ccacctactc cccactgaaa 4200 cttccacata ttaatctttt cccacgtaag gcaaatggtt ctttgaccaa ggatctcctt 4260 ccagcctcac aggcccattc tattctgtca tcatttcgta gtctcttcca tgtaggttac 4320 aagccactag cccatctctt agaacctctc atttcctttc catcgtggaa atctatcctc 4380 aaggaaatca cttctcagtg ttccatctgc tattccacta ctccccagga atttctcagg 4440 ccccctccct tctctacaca tcaagctcgg ggatttgccc tgcccaggac tggcaaattg 4500 actttactca catgccccga gtcaggaaac taaaatacct cttggtctgg gtagacactt 4560 tcactggatg ggtagaggcc ttttccacag ggtctgagaa ggccaccatg gtcatttctt 4620 cccttctgtc agacataatt cctcgttttg gccttcccac ctctatacag tctgataacg 4680 gaccagcctt tattagtcaa atcacccaag cagtttctca ggctcttggt attcagtgga 4740 accttcatac cccttatcat cctcaatctt caggaaaggt aaaatggact aatggtcttt 4800 taaaaacaca cctcacgaag ctcagccacc aactttaaaa aaaggactct gtcaagaata 4860 gagcccaaaa actcaccaac caaacaagta attacactga acccccttgg acactctcta 4920 attggatgtc ctgggtcctc ccaattctta gtcctttaat acctattttt ctccttcttt 4980 tatttggacc ttgtgtcttc tgtttagttt ctcaattcat acaaaaatgc atccaggcca 5040 tcaccaatca ttctatatga caaatgcgcc ttctaacaac cttaccgcaa aatcttcctt 5100 cagcttaatc tctcccactc taggttccca cgctgcccct aattccactc gaaccagccc 5160 tgagaaacat cactcatcat ctctccatac caccccccaa aattttcacc accccaaaac 5220 tttaccaata ttttgttttt tgttattttt cttattaata taaggagaca ggaatgtcag 5280 gcctctgagc ccaagctaag ccatcatatc ccctgtgacc tgcacgtata catccagatg 5340 gcctgaagta actgaagaat cacaaaagaa ttgaaaatgg cctgttcctg ccttaactga 5400 tgatattacc ttgtgaaatt ccttctcctg gctcatcctg gctgaaaagc tcccccactg 5460 agcacattgt gacccccgcc cctgcctgcc gagaactacc cactttgact gtaattttcc 5520 tttacctacc cacatcctat aaaacggccc caccctatct cctttcactg actctctttt 5580 cggactcagc ctgcctgcac ccaggtgaaa taaacagcct tgttactcac acaaagcctg 5640 tttggtgggc tcttcacacg gacacgagtg aaa 5673 <210> 275 <211> 469 <212> DNA <213> Homo sapiens <400> 275 tcccggcccc acaccaggaa ggtcaggtga ccatcaagca cccgtcaggc agttgttaag 60 ctgtctccct aaaataacaa ttggtcgcag ccggggccaa ggaaaggcag tctgccaata 120 gatagaaaca cctgaaactg gtgaccagca gcttcctgat aagatctcag gagttgagcc 180 agtggactca cccgtgtgct ctaagaggca gaatgggaag tttaactggt atataacctt 240 tctgtaggaa tgctagactg gtaagggaag aatgcccgaa gtgagcatgc gtacaactcc 300 agtaaacaca ttgcgcatga agcccctccc aaggtctagc aggccactgt gcatgtggaa 360 agcccatcct aagggaagaa tcaaggcaga agaggctcaa gaccccggaa gtatgccaat 420 gtgcaaaacc ccaagtcaat gatcagacag tgcacttgat ctcttaagt 469 <210> 276 <211> 6574 <212> DNA <213> Homo sapiens <400> 276 gtcaggcctc tgagcccaag ctaagccatc atatcccctg tgacctgcac gtatacatcc 60 agatggcctg aagcagctga agatccacaa aagaagtgaa aatagccagg tgctgcctta 120 gctgatgaca ttccaccact gtgacctgtt cctgccccac cctaactgat caattgacct 180 atgacaatac accctccctg cccttgtgat aatgtacttt gtgatattcc cctgccctta 240 agaaggtact ttgtgatatt cccccgccct taagaaggta ctgtgtgata ttcccccgcc 300 cctaagaagg tactttgtga tattcccccg cccttaagaa ggtactttgt gatattcccc 360 cgcccttaag aaggtacttt gtgatattcc cccgccctta agaaggtact ttgtgatatt 420 cccccgccct taagaaggta ctttgtgata ttcccccgcc cttaagaagg tactttgtga 480 tattcccccg cccttaagaa ggtactttgt gatattcccc cgcccttaag aaggtacttt 540 gtgatattcc cccgccctta agaaggtact tgtgatattc ccccgccctt aagaaggtac 600 tttgtgagat ccaccccctg cccacaacaa attgctccta actccaccgc ctatcccaaa 660 cctgtaagaa ctaatgataa tcccaccacc ctttgctgac tctcttttcg gactcagccc 720 gcctgcaccc aggtgattaa aaagctttat tgctcacaca aagcctgttt ggtggtctct 780 tcacatggat gtgcgcgaca tttggtgcca aaacccgaga atggttctaa atggccagaa 840 aatgacactt ttgatttctc catcctacaa gatctagata attttgtcga aaaatgggca 900 aatggtctga ggtgactgac atcccggcat tctttcacac atcggtccct ccctagtctc 960 tgctcccagt gcgacttgtc ccacatcttt cttctttctc ttctgtctgt tccttcagtc 1020 ccaaccccaa gcgtcactaa gtcttttgaa tcttcctttt ctacccaccc atctgacctc 1080 tccccttctt cccacactgc tcctcctcag gtcgctccct gccaggctga atcaggctcc 1140 agcttttctt gagcttccgc tcccctaccc tacaacccct ctatcacctc ccctgccaca 1200 cccagtctgg cttacagttt cattccatga cgagccctcc cctacctgcc caacaatttc 1260 ctcttaaaga ggtggctgga gctaaaggca tagtcaaggt taatgctcct ttttctctat 1320 cagacctttc ccaaatcagt tagtgtttag gctcttttcc atcaaatata aaaacccagc 1380 ccagttcatg gcccgtttgg caacaaccct tagatgcttt accgccctag acccagaggg 1440 gccagaaagc catcttattc tcaatatgcg ttttattacc caatctgctc ctgatactag 1500 aaaaagctcc aaaaattaga ttccagccct caaaccccac aataggactt aattaacctc 1560 gccttcaagg tgtacaataa taaaaaagag tcagccaagt ggcaacatat ttctgagttg 1620 cgattacttg cctctgccgt gagagaaacc ctagccgtat ccccagcaca caagaccttc 1680 aaattgccta aaccgcagag gacaggcgtt ccttcaggac ctcctccccc aggatgttgc 1740 tccacgtgac ggaaatctga ccactgggcc aaggaatgcc agcagcctgg gattcctcct 1800 aagctgcgtc ccatctctgc gggaccccac tggaaattgg actgtccaac tatcccagca 1860 gccactccca gagcccctgg aactctggcc caaggctctc tgactccttc ccagatcttc 1920 ttggttcagc agctgaagac tgatgctgcc cgatcgcctc ggaagcctcc tggaccatca 1980 cagatgcttt gggtaactct tacagtggag ggtaagtctg tccctttctt aatcaatacg 2040 gaggctaccc actccacatt accttctttt caagggcctt ttcccttgcc tccgtaactg 2100 ttgtgggtat tgacagccag gcttctaaac ctcttaaaac tccccaactc tggtgccaac 2160 ttggacaata ctcttttaag cactcctttt cagatattcc cacctgccca gcttccttat 2220 taggtcgaga cattttagcc aaattatttg cttccctgac tattcctggg ctacagccac 2280 acctcaataa cctcccttca caacccatca ttctgttctg gttctcaaat atgcttcctt 2340 tactattctt ttccatcctt catcccagcc tctcttcgct ttcacttgga ctgatcctga 2400 cacccatcag gctcagcaaa ttacctgggc tgtactgccg caaggcttca cagacagccc 2460 ccgttacttc agtcaagccc tttctcatga tttactttca ttctgtccat ctgcttctca 2520 ccttattcaa tattttcacg accttctact ttatagctgc ccccccccac caaaatcttc 2580 tcaacaggac accctcctgt tcctctaaca tctattctca aagggatatc acatattccc 2640 ctccaaagca caaatttctt cctcatcggt tacctatctc ggcatgattc ttcataaaaa 2700 cacacgtgtt ttccctgctg atcatgtcca gctaatctcc caaaccccaa ccccttctac 2760 aaagccacag ctcctttcct tcctaggcat ggttaagtac tttcaccttt ggatacctga 2820 ttttgccatc ctgactaaac cattacataa actcacaaaa ggaaacctac ctggccccat 2880 agatcctaga tcctttcccc actcctcttt ccattcctta aaaacagccc tagaagctgc 2940 tcccacacta gctctcccta actcatccca acccttttca ttacacacaa ccaaagtaca 3000 ggactgtgca gtcggaattc ttacacaaga gctgggaccg tgccctatag cctttctatc 3060 caaacaactc aacttcacaa ttctgggctg gccctcatgt ttgtgccatt taaatacttc 3120 tagaggccat caaaaatcac aggctatgct ccacttaccc tttacagctc tcacaacctt 3180 caagcattaa tatcctcctc atacctttca catttattgt ctgcccccca actcctccag 3240 ctctattcac tctttgttga aactccaata gtaactatta cccatgggcc tgatttcaac 3300 ccagcttctc atttagcacc caacacaagt cctgaaccac atgactgtat ttccctaaca 3360 cacataggat cttctccctt tcctcatatt tctaatcttc ccattccaaa cccggaccac 3420 acttggttta ttgatggcgg ttcttctaaa cccaatcaat tttcaccagc taaagctgga 3480 tatgctgtca tgtcccacac ctctattatt gaagctgctg cacttcctcc ctccaccact 3540 tcccaacaag ccaaactgat tgctttaact cgtgtgctct ctctagctaa aggaatgcac 3600 attaacattt atactgactc catatatgct ttccacatcc tccataacca tgctgccatc 3660 tgggtcaaaa gaggcttcct taccacacaa agctcttcca ctaataatgc ctccctaata 3720 gaggccctta aggttgttct cctgccagcc aaggctggaa tcattcattg taaaggacac 3780 cagaaaccta ctgatcttat tgcaaaaaaa aaataaccaa tgcctccaca cccgctaata 3840 ttccagcccc cactccggag ggccagtatt tttttttctc ctctatcact cccacctact 3900 cttcttctga aaacctgctc taccagtctt ttccaactca gggcaagtgg ttcttagatc 3960 atggaaaact catccttcct gcctcacaag ctcagtccat tctttcgtct tttcataacc 4020 tcttccatgt aagttacaag ccactagccc gcctcttaga acctctcatt tcctttaaga 4080 catttgccct gcatttcact ccatccttag ctaccttccc cttgttcttt ggactctcct 4140 cttagcccct cctcttgctt gcttataccc agccccatga atagcagtga acggttactc 4200 gtagacactt tgtactttct catacaccat aaaaatcaaa cctccccttc tacccagttg 4260 ctccatcaat ccccattaca acctctaacg gctgctgccc ttactaaatc cctaagagtc 4320 tgggtgcaag acacctgttt tggtgctccc tcttgtcttt tcactttaca tttccagttt 4380 tgccttacaa agttctcttc ttggacatga acagacactt ctcaaacgaa gacatttatg 4440 cagccaaaaa acacatgaag aaatgctcac catcactggc catcagagaa atgcaaatca 4500 aaaccacaat gagataccat ctcacaccag ttagaatggc aatcattaaa aagtcgggaa 4560 acaacaggtg ctggagaggt tgtggagaaa taggaacact tttacactgt tggtgggact 4620 gtaaactagt tcaaccattg tggaagtcag tgtggcgatt cctcagggat ctagaactag 4680 gaataccatt tgacccagcc atcccattac tgggtatata cccaaaggac tataaatcat 4740 gctgctataa agtcacgtgc acacgtatgt ttattgcact attcacaata gcaaagactt 4800 ggaaccaatc caaacgacca acaatgatag actggattaa gaaaacgtgg cacatataca 4860 ccatggaata ctatgcagcc ataaaaaatg agaagttcgt gtcctttata gggacatgga 4920 tgaaattgga aatcatcatt ctcagtaaac tatcgcaagg acaaaaatcc aaacaccgca 4980 tgttctcact cataggtgag atttgaacaa tgagaaccca tggacacagg aaggggaacg 5040 tcacactctg gtgactgttg tggggtgggg ggaaggggga gggatagcat taggagatat 5100 acctaaagct aaatgacgag ttaatgggtg cagcacagca gcatggcaca cgtatacata 5160 tgtaactaac ctgcacattg tgcacatgta ccctaaaact taaagtataa taataataat 5220 aataataata ataaaaaaga tgtcttcctc ctctgtggct ccttcaccta catgtgtcta 5280 cctattaatt agacaggcac atgtacacta gttagcctta cccccaaaat caatttgcaa 5340 ataggaccga acagcttcct gttcccctca tgacactaac actttacttc tattttgttt 5400 ttttattatt attattaata taagaaaaca ggaacaggcc ttgacttact cactgctgaa 5460 aaaggaagac tctgtgtatt tttaaatgaa gagtgttgtt tttacctaaa tcagtctggc 5520 ctggtatatg acaacataaa aaaatgcaag gatagagccc aaaaactcat caaacaagca 5580 aataattagg ctgaaccccc ttgggcactc tctagttgaa tgtcctgggt cctcccaatt 5640 cttagtcctt tgatacctgt ttttctcttt ctcttacttg gcccttgtgt cttccaatta 5700 atctctcaat tcctacaaaa ctgcatccag actatcacta atcactctat atgacaaatg 5760 ctgcttctaa caaccccaca atatcacccc ttaccccaaa atctttcttc agtttaatca 5820 ctcccactct aggttcccac actgccccta atcctgctca aagcagccct gagaaacatc 5880 gcccattatc tctccatacc acccgcaaaa atttttgcca ccccaacact tcaccaccat 5940 tttgttttgt ttttcttatt aacagaagaa gacaggaatg tcaggcctct gagctcaagc 6000 taagccatca tatcccctgt gacctgcatg tatacatcca gatggcctga agcaactgaa 6060 gatccacaaa agaagtgcaa atagccaggt cctgccttag ctgacgacat tccaccattg 6120 tgacctgttc ctgccgcacc ctaactgatc aattgacctt atgacaatac accctccccg 6180 cccttgcgat aatgtacttt gagatattcc cctacccttg agaaggtact ttgtgatatt 6240 tccccaccct tgagaaggta ctttgtgata ttctcccacc cttgagaagt tactttgtga 6300 tattccccca cccttgagaa ggtactttgt gatattcccc cacccttgaa aaggtacttt 6360 gtaatactct ccctgccctt gagaatgtac tttgtgagat ctaccccctg ctcctaactc 6420 caccgcctat cccaaaccta taagaactaa cgataatccc accacacttt gctcactctc 6480 ttttcagact cagcccacct gcacccaggt gattaaaaag ctttattgct cacacaaagc 6540 ctgtttggtg gtctcttcac atggacgtgc gtga 6574 <210> 277 <211> 3863 <212> DNA <213> Homo sapiens <400> 277 gtcaggcctc tgagctcaag ctaagccatc atatcccctg tgacctgcac atatatatcc 60 agatggcctg aagcaagtga agaatcacaa aagaagtgga aatggctggt tcctgactta 120 actgatgaca ttaccttgtg aaattccttc tcctggctca gctactcctc cactgagcac 180 cttgtgaccc ccgcccctgc ccgccagaga acaaccccct tttgactgta attttccttt 240 acctacccaa atcttataaa acggccccac cctatctccc tttgctgact ctcttttcgg 300 actcagcctg cctgcaccca ggtgaaataa acagccttgt tgctcacaca aagcctgttg 360 gtggtctctt cacacagacg cgtgtgacat ttggtgccga aacccaggac aggaggactc 420 cttcgggaga ccggtcccct gtcctcaccc tcactccatg aggagatcca cctgtgaact 480 ggggtcgtca gaccaaacaa cccaaggaac atctcaccaa tttcaaatca ggtaagtggt 540 cttttcactc tcttctccag cctctctcgc tacccttcaa tctccctgtc cttccaattc 600 cagttctttt tcctctctag tagagacaaa ggagacacat tttatccgtg gacccaaaac 660 tccggcgctg gtcatggact cgggaagaca gtcttccctt ggtgtttaat ccctgcgggg 720 acgcctgcct gattattcac ccacatttca ctggtgtctg atcaccacgg ggacacctcc 780 ttggtcattc acccacattc ccttggtggc aagtcaattg cggggttgcc tgctttggct 840 gctcacccac actgcagccc agggctgctc accaccccct tctccgtgtc tctaccctct 900 cttttctctg ggcttgcctc cttcactatg ggcaaccttc caccctccat tcccccttct 960 tctcccttag cctgtgttct cagaaactta aaacctcttc aactctcacc tgacctaaaa 1020 cctaagcatc ttattttctt ctgcaacacc gcttgggccc caatacaaac tcgataatgg 1080 ttctaaattg ccagaaaata gcacttttga tttctccatt ttacaagacc tggatgaatt 1140 ttgtcaaaaa atgggcgaat gggtctgagg tgctcgacgt ccaggcattc ttttacacat 1200 tggtccctcc ctagtctctg ctcctaatgc gactcacccg atatccttct tctttctctc 1260 ctgtctgttc cttaagtctg catcccaagc tctgagtcct ttgaatcctc cttttctaca 1320 gacccatctg acctctcccc tcctccccag gctgttcctc gccaggccga gccaggtccc 1380 aattcttcct cagcctccac tcccataccc tataatcctt ctgtcccctc ccctgctcac 1440 acctggtcca gcttacagtt tcattccgaa actagccctc ccccacctgc ccaataattt 1500 cctcttaaag agatggctgg agctgtaggc atagtcaagg ttaatgctcc tttttcttta 1560 tctgacctct cccaaatcag ttagcgttta ggctcttttt catcaaatat aaaaacccag 1620 cccagttcat ggctcatttg gcagcaaccc tgagacactt tacagcccta ggccctgaaa 1680 ggtcagaagg ccgtcttatt ctcaatgtgc attttattac ccaatcagct cccgacattt 1740 aaaaaaagct caaaaaatta gatcctggcc ctcaaacccc acaacaggac ttaattcacc 1800 tcgccttcaa ggtgtacaat aatagagaag agttacaatt acttgactct gttgtgagac 1860 aaaacccagc cacatctcca gcacacaaaa acttcaaaat gcctaagcca cagtggtcaa 1920 gcattcctac aggacctcct ccatcaggat cttgcttcaa gtgccagaaa tctggccact 1980 gggccaagga atgcccacag cccaggattc ctcccaagcc atgtgccatc tgtgtgggac 2040 cccactggaa atcagactgg ccaactcacc cggcagccac tcccagagcc cctggaaccc 2100 tggcccaagg ccctctgact gactccttcc cagatctcct tggcttagtg gctaaagact 2160 gatgctgccc aatcacctca gaagcctcgt ggaccatcac agatactttg gataactctt 2220 atagtggagg gtaagtccgt ccccttctta attaaaatat ggaggctacc cactccacat 2280 tactttcttt tcaagggcat gtttcctttg cctccataac tgttgtgggt attgatggcc 2340 aggcttctaa acctcttaaa actccccaac tctgatgcca acttggacaa cattctttta 2400 tgcactcctt tttagttatc cccacctgcc cagctccctt attaggttga gacactttaa 2460 ctaaattatc tgcttccctg actattccta ggctatagcc acacctcatt gccgcccttt 2520 tccctagttc aaagcctcct ttgcatcctc ctctcatatc ccccccacct taacccacaa 2580 gtatgggacc cctctactcc ctccgtggca accaatcaca cgcccattac tatcccatta 2640 aaacctaatc acccttaccc tgctcaacac caatatccca tcccacagca cactttacaa 2700 ggattaaaac tcattatcac tcacctgtta cagcatggcc ttttaaagcc tataaactct 2760 ccttaccatt tcctatttta cctgtccaaa aaccagacaa gtcttacaag ttagttcagg 2820 atccacactt tatcaaccaa attgttttat ctatccaccc cgtggtgcca aacccacata 2880 ctctcctatc ctcaatacct ccctccacaa tccctccaca acccattatt ctgttctgga 2940 tctcaaacat gctttcttta ctattccttt gcacccttca tcccagcctc tcttcgcttt 3000 cacttagact gaccctgaca cccatcaggc tcagcaaatt acctgggctg tactgccgca 3060 aggcttcatg gacagccccc attacttcaa tcaagcccaa atttcttcct catcccttac 3120 ctatctcggt ataattcttc atgaaaacac acgtgctctc cctgctgata gtgtccggct 3180 aatctcccaa gccccaaccc cttctacgaa acagctcctt tccttcctag gcatggttag 3240 gtacttccac atttggatac ctagttttac catcctgact aaaccattat atgaactcac 3300 aaaagcaaac ctagctgacc ccatagatcc taaatccttt caccactcct ctttcccttc 3360 cttaaaaaca gccctaaaag ctactctcac actagctctc cctaactcat cccaaccctt 3420 ttcattacac acagccaaaa tacagagctg tgtggtcaaa attcctacac aacagccagg 3480 accatgccct gtactctttc tgtccaaaca acttgccctt actgttttag gctggcccct 3540 acattattcc tgataccaca cctgaccccc atgactgtat ctctctgatc cacctgacat 3600 tcactccatt tccccatatt tccttctttt ctgttcctca ccctgatcac acttggttta 3660 ttgatggcaa ttccaccagg cctaatcgcc actcaccagc aaaggcaggc tatgctatag 3720 tatcttccac atctattatt gaggctattg ctcttccccg ctccactatc tctcagcaag 3780 ccgaactcat tgccttaact caggccctca ctcttgcaaa aggagtacgt gtcaatattt 3840 atactgactg taaatatgcc ttc 3863 <210> 278 <211> 354 <212> DNA <213> Homo sapiens <400> 278 ccacaaaaaa agtgaaaata gccagttcct gccttaactg atgacattcc accattgtga 60 tttgttcctg ctccacccta actgatcaat tgaccttgtg acattccttc tcctggacaa 120 tgagtctcag aatctcccca ctgagcactt tgtgaccctt gcccctgccc acaagaaaaa 180 gaaacccttt aactgtaatt ttccattacc tacccaaatc ctataaaact gccccacccc 240 atctcccttt gctgacctct ttttcagact cagtccgcct gcacccaggt tattaaaaag 300 ctttattgct cacgcaaagc ctgtttggtg gtctcttcac atagacacat gtga 354 <210> 279 <211> 4057 <212> DNA <213> Homo sapiens <400> 279 cttctccctt agcctgtgtt ctcaagaact taaaacctct ttaactcaca cctgacctga 60 aacataaatg ccttcttttc ttgtgcaata ttgctggccc ccaaaacaaa atcaacaatg 120 gttccaaata gccagaaaat ggcacttttg atttctccat cctacaagac ctagataatt 180 tttgtcaaaa aatgggcaaa tggtctgagg tgactgacat ccagacattt ttcacacttt 240 gttcccaccc tagtgtctgt tcccaatgca actcttccca aatcctcctt ctttccaaac 300 tgcctgtccc ttcagtccca aacccaagtg tcactgagtc ttttgaatct tcctttttca 360 cagtcccatc tgacctctct cctcctcccc agactgcttc tcctcaggtc actccctgcc 420 aggctgaatc aggctccaac tcttcttcag cctctgctcc cccaccctac aacacttctg 480 tcacctccct tccccacacc tgttctggct tacagttttg ttctgcaact agctctagcc 540 cacctgctca aaaatttcct cttacagagg tggctggagc tgaaggcata gtcaaggtta 600 atgctccttt ttctttagct gacctctccc aaataagtca gcatttaggc tctttctcat 660 cagacccccc taaatatata caggaattcc aatatctaac tatgtcctac aatttaacat 720 tgagtgactt aaatgtcatc ctaacttaaa ccctctccac agatgaatgg gaaagattat 780 tttttctcta gcccaatctc atgctgacaa ccaccggctt cataagccag acctccagga 840 aggcattaga gtagttcccc gagaggatcc ccaatggaac tatcaggcag attcctcagg 900 tatagctagg tgagatcaca tgatttcctg cctagttgaa gggcttaaaa aggcagcata 960 caaacctgtt aattatgaca aacttaaaga aactactcaa ggaaaaaatt aaaacacagc 1020 ccagcccatg gctcatttgg cagcaaccct gagaagcttt acagccttgg acccagaagg 1080 gccagaaggc catcttactc tcaataagcg ttttattact caatcagcta aaaccttcaa 1140 aaattggaat ctggccctaa aaccccacaa caagaattaa ttaaccttgc ttttaaaaag 1200 tgtacaataa taaagaagag gcagccaagt ggcaacatat ttctttgtcg caattacttg 1260 cctctgcttt gggagaaacc ccatccaaat ctctggcaca aaagaacttc agaatgccta 1320 aacagcagca gtcagccatt cctccagggt ctcctccccc aggatcttgc ttcaagtgct 1380 gaaaatctgg ccactgcacc aagatatgcc tgaagcttgg tattcctcct aacctgtgtc 1440 ccatctgtgt gggaccccac tggcaattga actgtctgaa tcacccagca accactccca 1500 gagcccttgg aactctggcg tcaggatctc tgactaactc cttcccagat cttctcagct 1560 ttgcggttga agactgacac gcccaatcac ctcggaagcc tggacaatta cagacacttt 1620 aggtaactct tacagtggaa ggtaagtcca tccccttctt catcaatatg gaggctaccc 1680 actccacatt accttcgttt caagggcctg tttcccttgc ctccataact gttttggtta 1740 ttgatggtca ggcttctaag cctcttaaaa ctccaactct ggtgccaaca tggacaacat 1800 tcttttatgt actccttttt agttatcccc accttcccag ctcccttatt aagtagagac 1860 atttaaacta aattatctgc ttccctgact attcctgggc tacagccaca cttcattgcc 1920 acccttttcc ccagttcaaa gcctctttac atcctcccct tgtgtctccc taccttaatc 1980 cataagtatg ggacacctct actccctgct tagtaactga tcatgtactt tttatcatcc 2040 attaaaaact aattgccctt atcccagtcc acatcaggct ttaaaagggt taaagcctgt 2100 tatcatccac ctgttacaac atgtcctttt aaagcctaca aactttcctt aaaactctcc 2160 tatcctaccc atccaaaaac cagacaagtc ttacagtctg gtcaaggatc tttgccttat 2220 caactaaatt gtcttgccta tctaccccgt ggtaccaaac ttatgcattc ttctatcttc 2280 aatacttccc tccaaaagcc attattctcc tctacatctc aaacatgctt cctttactat 2340 tactttgcac ccttcatcca aggctctctt cactttcact tggacaatga atcaccttga 2400 tgaagtccta ttctttactt ttatactcat tcttattctc attgcaattc ttatgccacc 2460 ctctacctct ccacagctat ctccactaca ctatcaatct cattcactta gctgtttcta 2520 atccctcctt agcaaacaat tgttggcttt gcatttccct ttcttcctgc acttacacag 2580 ctgtccctgc cttacataca gactgggtaa catctccttt ctccctatat ctctgaactt 2640 tttttttttt aacaacattc acctttaccc tccagaagaa cttctttact ttctagacag 2700 atccagcaag acctccccag acatttcaca tcagcaagct gacacccttc tccgcactta 2760 cttaaaaaac ctttctcctt atattaactc taattcccct ataattggac ccctcacaac 2820 acacactact attcctgtgg ctgttccctt atgcatctct tggcaaagac ccactggaat 2880 tcccctgggt agcaccttct ctatgctcct tcactcttca tatgtaaagc ctaattacac 2940 ccattcctga aaaaaatagg gctttccagc tccatattac aaataagccc tctatcaata 3000 cagacaaact taaaagcact agcagttatt attgcttaaa aagacattta ccctgtattt 3060 aacaccatcg ttcgctacct tccccttgct tttcactctt ctcccaggcc ctcttcttct 3120 ttgcttatat ccagctctgt aaataacagt gaaaggttgc gcatagacac tcaaagcttt 3180 ctcatacacc ataaaaatca cacctcttcc tgtatgcagt tgccccatca atccccatta 3240 caacctctaa tggattctgc cctcactaga tccctaaaga gtctgggtgc aagacacctc 3300 ttttagtact ccttcttatc ttttcacttt gcatttccag tttttccttg cacaagttct 3360 cttcttcttc tgtgaatcct ctatctacat gtgtctacct gctaattgga cagatatgtg 3420 cacactagtt ttccttactc caaacaccaa gcaaataatt atgctgaacc cccttgggca 3480 ctctgtaatt ggatgtcctg ggtcctccca attcgtagtc ctttaatacc tgtttttctc 3540 cttctctttt tcagaccttg tgtcttccat ttagtttctc tattcataca aaactgcatc 3600 caggccatca tcaatcattc tacatgacaa atgctccttc taacacctcc ataatatcac 3660 cccttacccc aaaatctttc ttcagtttaa tctctcccac tctaatttcc cactctgccc 3720 caatcccgct tgaaatagcc ctgagaaaca tcacccatta tctctctgta ccacccccaa 3780 aaattttcat taccccaata cttcaccatc attttgtttt atttttctta ttaatataag 3840 aagacaggaa tgtcaggcct ctgagcccaa gcctgcatgt atacatccag atggcctgag 3900 ggcaactgaa gaaccacaaa agaagagaaa atggtcagtt cctgccttaa ctgatgacat 3960 taccttatga aattccttct cctggacaat gggtctcaga tgcttcctgc tgagcacctt 4020 gtgaccccct gcccctgcct tcaaaaaagc aaccccc 4057 <210> 280 <211> 351 <212> DNA <213> Homo sapiens <400> 280 accaaagaag tgaaaatagc cagttccggc cttaactgat gacattccac cattgtgatt 60 tgttcctgcc ccaccctaac tgatcaattg accttgtgac attccttctc ctggacaatg 120 agtctcagaa gctccccact gagcacccta taacccccac ccctgtccac aagagaaaac 180 ccctgtttga ctgtaatttt ccactatcta cccaaatcct ataaaactgc cccaccccat 240 ctccctttgc tgactccttt tttggactca gtccacctgc acccaggtga ttaaaaagct 300 ttgttgctca cataaagcct gtttggtggt ctcttcacat ggccaagcat g 351 <210> 281 <211> 160 <212> DNA <213> Homo sapiens <400> 281 tgaaatgtgt ccaaaatgta aaaaaggaaa acattgagct agtcagtgtc actctaagtt 60 tgataaagat gggaacccaa tttcaggaaa tgccatgagg tgccagccca tcccggcccc 120 cactccagac tggggcattt ccagctcagg ccattccttc 160 <210> 282 <211> 8384 <212> DNA <213> Homo sapiens <400> 282 gtcaggcctc tgagcccagg ccaggccatc gcatcccctg tgacttgcac gtatacatcc 60 agatggcctg aagtaactga agatccacaa aagaagtaaa aacagcctta actgatgaca 120 ttccaccatt gtgatttgtt cctgccccac gctaactgat caatgtactt tgtaatctcc 180 cccaccctta agaaggtact ttgtagtctc ccccaccctt aagaaggttc tttgtaattc 240 tccccaccct tgagaatgta ctttgtgaga tccacccctg cccaccagag aacaaccccc 300 tttgactgta attttccatt accttcccaa atcctataaa acggccccac ccctatctcc 360 cttcactgac tctgttttcg gactcagccc gcctgcaccc aggtgaaata aacagccatg 420 ttgctcacac aaagcctgtt tggtggtctc ttcacatgga cgcgcgtgaa atttggtgcc 480 gtgactcaga tcgggggacc tcccttggga gatcaatccc ccgtcctcct gctctttgct 540 ccgtgagaaa gatcaaccta caacctcagg tcttcagacc gaccagccca agaaacatct 600 caccaatttc aaatccggta agcggcctct ttttactctc ttctccaact tccctcacta 660 tccctcaacc tccttctcct ttcaatcttg gtgctacact tgaatctctc ccttctctta 720 atttcaattc ctttcatttt ctggtagaga cgaaagagac acgttttatc cgtggaccca 780 aaactctggc gctggtcacg gactgagaag gcagccttcc cttggtgttt aatcattgca 840 gggacgcctc tctgattata cgcccacgtt tcaagggtgt cagaccacgc agggatgcct 900 gccttggtcc ttcaccctta gcggcaagtc ccacttttct ggggaagggg caagtacccc 960 aacccctttt ctccttgtct ctaccccttc tctgcttttc tggggaaggg gcaagtaccc 1020 caaccccttc tctccttgtc tctacccctt ctctgctttc ctggggcagg ggcaagtacc 1080 cctcaacccc ttctccttca ccctcagtgg caagtcccac tttcctgggg caggggcaag 1140 tacccctcaa ccccttctcc ttcaccctta gtggcaagtc ccactttcct agggggcaag 1200 aaccccccag ttgcttattt ccacacccca acctcttatc tctgagcccc aatcccttat 1260 ttctgcaccc tgacctctta tttccgtgcc ccaaaccctt ctctgctttt ctggagggca 1320 agaacccccc accccttctc cgtgtctcta ctcttttctc tgggcttgcc tgcttcacta 1380 tgggtaagct tccaccttcc attcctcctt cttctccctt agcctgtgtt ctcaaaaact 1440 taaaacctct tcaactcaca cctggaccta aaactaaatg ccttattttc ttctacaatt 1500 ttgcttgacc ccaatacaaa ctcgacagga gttccaaata gccggaaaat ggcactttca 1560 atttttccat cctacaagat ctaaataatt cttgtcgtaa aatgggcaaa tggtctgagg 1620 tgcctgacgt ccaggcattc ttttacacat cagtcccttc ctagtctctg tgcccagtgc 1680 aactcgtcct aaatcttcct tctttccctc ccgcctgtcc cctcagtccc aaccccaagc 1740 gtcactgagt ctttctaatc ctccttttct acagacccat ctgacctctc ccctcctcgc 1800 cagcccaagc taggtcccaa tacttcctca gcctccactc ctccacccta taatccttct 1860 atcacctccc ctcctcacac ctggtctggc ttacagtttg gttctgtgac tagccctccc 1920 ccacctgccc agcaatttat tcttaaaaag gtggctggag ctaaaggcat agtcaaggtt 1980 aatgctcctt ttttttttat cccaaatcag acagcgttta ggctttttca tcaaatataa 2040 aaacccagcc cagttcatgg ctcgttcggc agcaaccctg agacgcttta cagccctgga 2100 ccctaaaagg tcaaaaggcc gtcctattct caatatacat tttattaccc aatctgctcc 2160 cgacattaaa taaaactcca aaaattaaat tccggccctc aaaccccaca acaggattta 2220 attaacctcg ccttcaaggt gtataataat agaaaaaagt tgcaattcct tgcctccact 2280 gtccccagcc acatctccag cacacaagaa cttccaaacg cctgaactgc agcggccagg 2340 cgttcctcca gaacctcctc ccccaggagc tctctacaag tgccagaaat ctgaccacca 2400 ggccaaggaa tgcctgcagc ccaggattcc tcctaagctg tgtcccatct gtgcgggacc 2460 ccactggaaa ttggactgtt caactcacct ggcagccact cccagagcct gtggaactct 2520 ggcccaaggc tctctgacag actccttctc ggcttagcgg ctgaagactg atgctgctcg 2580 atcgcctcgg aggcccggta gaccatcaca gacgccgagc tttgggtaac tctcacagtg 2640 gaaggtaagt ccgtcccctt cttaatcaat atggaggcta cccactccac attaccttct 2700 tttcaagggc ctgcttccct tgcctccata actgttgtgg atattgacgg ccaagcttct 2760 aaacctctta aaactcccca actctggtgc caacttagac aatactcttt taagcactcc 2820 tttttagtta tccccacctg cccagttccc ttattaggct gagacacttt aactaaatta 2880 tctgcttccc tgactattcc tggactacag ctacatctca ttgccgccct tcttcctaat 2940 ccaaagcctc ctttgcgtcc tcctcttata tccctccacc ttaacccaca agtataagat 3000 acctctactc cctccttggt gaccgatcat gcacccctta ccatctcatt aaaacctaat 3060 cacccttacc ctgctcaatg tcaagatccc atcccacagc acactttaaa aggattaaag 3120 cctgttatca ctcgcctgct acagcatggc cttttaaagc ctataaactc tccttaccat 3180 tcccccattt tacctgtcct aaaaccagac aaggcttaca ggttagttca ggatctgtgc 3240 cttatcaacc aaattgtttt gcctatccac cccatggtgc caaacccata tactctccta 3300 tcctcaatac ctccctctac tacccattat tctgttctgc atctcaaaca tgctttcttt 3360 actattcctt tgcacccttc atcccagcct ctctttgcct tcatttagac tgaccctgac 3420 acccattagg ctcagcaaat tacctgggct gtactgccgc aaggcttcac agacagcccc 3480 cattacttca gtcaagccca tatttcatcc ccatctgtta cctatctcgg cataattctc 3540 ataaaaacac acgtgctctc cctgctgatc gtgtccaatt aatctcccaa acctcaatcc 3600 cttacaaaag aacaactcct ttccttccta ggcatggtta gtgtggtcag aattcttaca 3660 caagagccag gaccacaccg tgtagtcttt ctgtccaaac aacttgacct tactgtttta 3720 gcctagccct catgtctgcg tgcagcggct gccgctgctt taatactgtt agaggcccta 3780 aaaatcacaa cctatgctca actcactctc tacatttctc ataacttcca aaatctattt 3840 tcttcctcat acctgatgca tatactttct gttccccagc tccttcagct gtactaactc 3900 tttaagtccc acaattacca ttgttcctgg cccggacttc aatctggcct cccacattat 3960 tccggatacc acacctgacc ctcatgactg catctctctg atccacctga cgttcacccc 4020 atttccccac atttccttct tccctgtttc tcaccctgat cacacttggt ttattgatgg 4080 tagttccacc aggcctaatc gccattcacc agcaaaggca ggctatgcta tagtatcttc 4140 cacatctatc attgaggcta cctctctgcc tccctccact acctctcagc aagccgaact 4200 agttgcctta actcaagccc tcactcttgc aaaaggacta cgtgtcaata tctatactga 4260 ttctaaatat gcctttcata ttctgcacca ccatgcagtc atatgggctg aaagaggttt 4320 cctcactaca caagggtcct ccatcattaa tgcctcttta ataaaaactc tgctcaaggc 4380 tgctttactt ccaaaagaag ctggggtcat tcactgcaag gggcatcaaa aggcgtcaga 4440 tcccattgct ctaggcaacg cttatgctga taaagtagct agacaagcag ctagctctcc 4500 aacttctgtc cctcacggcc agtttttctc cactttagtc actcccacct actcccccac 4560 tgaaacttcc acctatcaat ctcttcccac acaaggcaaa tggttcttag accaaggaaa 4620 atatctcctt ccagccttac aggcccattc tattctgttg tcatttcata acctcttcca 4680 tgtaggttac aagccactag cccatctctt agaacctctc atttcctttc catcatggaa 4740 atctatcctc aaggagatca cttctcagtg ttccatctgc tattctacta ctcctcaggg 4800 agtgttcagg cctcctccct tccctgcaca tcaagctcga ggatttgccc ctgcccaaga 4860 ctggcaaatt gactttactc acatgcctcg agtcagaaaa ctaaaatatc tcttagtctg 4920 ggtagacact ttcactggat gggtagaggc cttccccaca gggtctgaga aggccacctt 4980 ggtcatttct tcccttctgt cagatataat tccttggttt ggccttccca cctctataca 5040 gtctgataac ggaccagcct ttactagcca aatcacccaa gcagtttctc aggctcttgg 5100 tattcagtgg aaacttcata tcccttacca tcctcaatct tcaggaaagg tggaacggac 5160 taatggtctt ttaaaggcac acctcaccaa gctcagcctc caacttaaaa aggattggac 5220 agtactttta cctcttgctc ttctcagaat cagagcctgt cctcgagatg ctacagggta 5280 cagtccattt gaacttttat atggatgcat tttcttgctt ggccccaacc tcatcccaga 5340 caccagccct ctaggtgact atcttccagt cctccagcag gctagacagg aaattcgcca 5400 ggctgctaat cttctcttgc ctactccaga tccccagcca tatgaagaca ccctagctgg 5460 atgatcagtt cttgttaaga atctgacccc tcaaactcta caacctcgat ggacaggacc 5520 ctacttagtc atctatagta ccccgactgc cgtccgcctg caggatcctc cccactgggt 5580 tcaccattcc agaataaagc tgtgtccatc ggacagccag cctaatccct cctcttcctc 5640 ctggaagtcg caaatactct cccctacttc ccttaaactc actcgtattt ctgaagaaca 5700 gtaataaccc ttatgagcct aatacatcac ttcattctat taggtctttt catccttacc 5760 ctactttttg caacagggct ttacgaagcc acccccacca cttaggccga gccccaaaaa 5820 actagtcatc cctactgtct tctgtccggt catactccta ttctccattc tcaactactt 5880 ataaatgccc tactcctgtt tacaccgccg gtttacactg tttcttcaag ccatcacagc 5940 tgatatctct tggtgctatc cccaaactgc cactcttaac tccctcttag agtgggtaga 6000 tgatctttgc tggcaaggca ccctccaata cttccaccct gatgaagttc tattctttac 6060 ttttatactc actcttattc tcattcccat tcttatgcca ccctctacct ctccccagct 6120 atctccacca cactatcaac cttacccatt ctctcctagc cgcttctaat ccctccttag 6180 cgaacaactg ctggctttgc atttctcttt cttccagtgc ctacacagct gtccccgcct 6240 tacagacaga ctgggcaaca tctcccatct ccctacacct ccgaacttcc tttaacagcc 6300 ctcaccttta ccctcctgaa gaactcactt actttctaga caggtccagc aagacttccc 6360 cagacatttc acatcagcaa gctgctgccc tcttcgcact tatttaaaaa acctttctcc 6420 ttatattaac tctactcacc ccatatttgg acctctcaca acacaaacta ctattcctgt 6480 ggccactcct ttatgtgtct ctcagcaaag acccactgga attcccctag gtaatctttc 6540 accttctgga tgttccttta ctcttcatct ctgaagtcca actacacaca tcactgaaat 6600 aattggagcc ttccagctcc atattacaga caagccctct atcaatactg acaaacttaa 6660 aaacattaac agtaattatt gcttaggaag acacttgccc tgtatttcgc tccatccttg 6720 gctaccttcc ccttgctcat cagactctcc tcccaggccc tcttcttgtt tacttatact 6780 cagccccgaa aataacagtg aaaggttgct tgtagatact caacgttttc tcatacacca 6840 tgaaaatcga acctcaccct ctacgcagtt accccatcat tccccattac aatctctgac 6900 agctgctgcc ttagctggat ccctaggagt ctgggtaaaa gacacccctt tcagcactcc 6960 ttctcatctt tttactttac atctccagtt ttgccttgca caaggtctgt tcttcctctg 7020 tggatcctct acctacatgt gtctacctgc taattggaca ggcacatgca cactagtctt 7080 ccttaccccc aaaattcaat ttgcaaatgg gaccgaagag ctccctgttc ccctcatgac 7140 accgacatga caaaaaagag ttattccact aattcccttg ctggtcggtt taggactttc 7200 tgcctccact attgctctcg gtactggaat agcaggcatt tcaacctctg tcacgacctt 7260 ctgtagcctc tctaatgact tctctgctag catcacagac atatcacaaa ctttatcagt 7320 ccgccaggcc caagttgact ctttagctgc agttgtcctc caaaaccgcc gaggccttga 7380 cttacttact gctgaaaaag gaggactctg catattctta aatgaagagt gttgttttta 7440 cctaaatcaa tctggcctgg tgtatgacaa cataaaaaac tcaaggatag agcccaaaaa 7500 cttgacaacc aagcaagtaa ttacactgaa cccccttggg cactctaatt ggatgtcctg 7560 ggtcctccca attcttagtc ctttaatacc catttttctc ctccttttat tcggaccttg 7620 tatcttccgt ttagcttctc aattcatcca aaactgtatc caggccatca ccaatcattc 7680 tatacgacaa atgtttcttc taacatcccc acaatatcac cccttaccac aagacctccc 7740 ttcagcttaa tctctcccac tctagattcc cacgctgccc ctaatcctgc ttgaagcagc 7800 cctgagaaac atcgcccatt ctctctccat accacccccc aaaaattttc gccactccaa 7860 cacttcaaca cttattttgt tttatttgtc ttattaatat aagaaggcag gaatgtcagg 7920 cctctgagcc caggccaggc catcacatcc cctgtgactt ccacgtatat atccagatgg 7980 cctgaagtaa ctgaagatcc acaaaagaag taaaaacagc cttaactgat gacattccac 8040 cattgtgatt tgttcctgcc ccaccctaac tggtcaatgt actttgtaat ctcccccacc 8100 cttaagaagg tactttgtag tctcccccac ccttaagaag gttctttgta attctcccca 8160 cccttgagaa tgtactttgt gagatccacc cctgcccacc agagaacaac cccctttgac 8220 tgtaattttc cattaccttc ccaaatccta taaaacggcc ccaccccatc tcccttcgct 8280 gactctcttt tcggactcag cccgcctgca cccaggtgaa ataaacagcc atgttgctca 8340 cacaaagcct gtttggtggt cccttcacac ggacacgctt gaaa 8384 <210> 283 <211> 790 <212> DNA <213> Homo sapiens <400> 283 gagagacagg actagctgga tttcctaggc cgactaagaa tccctaagcc tagctgggaa 60 ggtgaccgct tccaccttta aacacggggc ttgcaattta tctcacatct gaccaatcag 120 atagtaaaga gagctcacta aaatgctaat taggcaaaag caggaggtaa agaaatagcc 180 aatcatctat ttcctgagag cacagtggga gggacaagga tcagcatata aacccaggca 240 tttgagccag caagggcaac cccctttggg ttgcctccct ttgtatggga gctctgtttt 300 cactctatta aatcttgcaa ctgcactctt ctggtctgtg tttgttatgg ctcaagctgg 360 gctttcactt gccatctgtc caccactgct gctggctgcc gtcgcagacc cgccactgac 420 ttccatccct ccagatccaa cagggtgtcc gctgtgctcc tgatccagtg aggcgcccat 480 tgctgctccc gatcgggcta aaggcttgcc attgttcctg cactgctaag tgcctgggtt 540 tgtcctaatc aagctgaaca ctagtcactg ggttccatgg ttctcttccg tgacccacgc 600 cttctaatag agctgtaaca ctcaccacat ggtccaaaat tccattcctt ggaatccgtg 660 aggccaagaa ccccaggtca gagaacacga ggcttgccac catcttggaa gtggcctgct 720 gccatcttgg aagcagccac caccatattg ggagctctgg gagcaaggac ccctccaccc 780 cagtaacact 790 <210> 284 <211> 983 <212> DNA <213> Homo sapiens <400> 284 gtgggggaaa gaaagagaga tcagactgtt actgtgtcta tgtagaaaaa ggaagacata 60 agaaactcca ttttgatctg tactaagaaa aattcttctg ccttgagatg ctgttaatct 120 gtaaccctag ccccaaccct gtgctcgcag aaacgtgtgc tgtattgact caaggtttaa 180 tggatttagg gctgtgcagg atgtgctttg gtaaaaatgt gtttgcaggc agtatgcttg 240 gtaaaagtca ttgccattct ccagtctcaa gtaaccaggg acaccataca ctgcggaagg 300 cagcagggac ctctgcccaa gaaaacctgg gtattgtcca agatttcccc cactgagaca 360 gcctgagaga tggcctcgtg ggaagggaaa gacctgaccg tcccccagcc cgacacccat 420 aaaaggtctg tgctgaggag gattagtgaa agaggaaggc ctctctgcag ttgagataag 480 aggagggcat ctgtctgctg ctcgtccctg ggaatggaat atctcggtgt aaaacccgat 540 cgtacattct atttactgag ataggagaaa actgccttat ggctggaggt gagacacact 600 ggcagcaata ctgctcttta ctgcactgag atatttgtgt aaagtcaaac ataaatctgg 660 cctacgtgca catccaggca cagctccttt ccttaaattt atctatgaca ccgagtcctt 720 tgctcacgtt ttcctgctga ccctctcccc accattaccc tatagtcctg ccacatcccc 780 ctcaccgaga tagtagggat agtgatcaat aaatactgag ggaactcaga gaccagtgcc 840 ggtgcaggtc ctcacttgct gagcaccggt cccctgggcc cacttttctt cctctatact 900 ttgtctctgt gtcttatttc ttttctcagt ctctcgtctc caccttgtga gaaatactca 960 gaggtgtgga ggggcaggcc ccc 983 <210> 285 <211> 6208 <212> DNA <213> Homo sapiens <400> 285 gtcaggcctc taagccctag ctaagccatc atatcccctg tgacctgcat gtacacatcc 60 agatggccgg ttcctgcctt aactgatgac attctcccac aaaagaagtg aaaatggcct 120 gttcctgcct taactgatga cattgtcttg tgaaattcct tctcctggct caaaatctcc 180 cctactgagc accttgtgac ccctactctg cctgccagag aacaaccccc cttggactgt 240 aattttcctt tatctaccca aatcctataa aacggcccca cccttatctc ccttcactga 300 ctctcttttc ggactcagcc tacctgcacc ctggtgaaat aaacagcttt attgttcaca 360 caaagcctgt ttggtggtct cttcacacgg acgtgagtga aatttggtgc cgtgactcgg 420 atcgggggac ctcccttggg agatcaatcc cctgtcctcc tgctctttgc tctgtgagaa 480 agatccacct atgacctcag gtcctcagac caaccagccc aagaaacatc tcaccaattt 540 caaatccggt aagcagcctc tttttactct cttctccaac ctccctcact atccctcaac 600 ctgtttctcc tttcaatctt ggcgccacac ttcaatctct cccttctttt aatttcaatt 660 cctttcattt tctggtagag acaaaggaga cacgttttat ccgtggaccc aaaactccag 720 cactggtcac ggactaggaa ggcagccttc ccttggtgtt taatcattgc aaggacacct 780 ctctgattat tcacccatgt ttcagaggtg tcagaccacg caaggacgcc tgccttggtc 840 cttcacccat agcggcaagt cccgcttttc tgggggaggg gcaagtaccc caaccccttc 900 tctctgtgtc tctacccctt ctccaccttt ctggagggca agaaatcccc aaccccttct 960 tcttcactct tagcagcaag tcccactttt ctaggggagg ggcaagtacc ccaacccctt 1020 ctcttcatgt ctctacccct tctccacctt tctgtaaggc aagaaacccc cagccccttc 1080 tccttcaccc ttagcagcaa gtcccatttt tctgggggag gggcatgtac cccaaccttg 1140 tatctctgcg ccccgatccc ttatttccac gctccgacct cttatatctc tgtgccccaa 1200 tcccttattt ctgtgcccca acctcttata tctctgcacc ctgctccctt atttccgtgc 1260 cccaacctcg tatctctgtg ccccgacccc tttcctgctt ttctggaagg taagaacccc 1320 cgaaccgctt ccctccatgt ctctactctc ccttttcttt aaacttgcct ccttcactat 1380 aggcaacctt ccaccctcca ttcctccttc ttctccctta gcctgtgttc ttaagaacat 1440 aaaacctctt caactcttgc ctgacctaaa acctaaatgc cttactttct tctacaatgc 1500 cgcttgaccc caatacaaac ttgacaatgg ctctaaatgg tcagaaaacg gcactttcga 1560 tttctccatc ctacaagacc taaataattt ttgtcgaaaa ataggcaaat ggtctgaggt 1620 gcctgacgtc caggcattct tttacacatc tgtccctccc tagtctctct gcccagtgca 1680 actagtccca aatcttcctt ctttccctcc tgcctgtctc ctcagtccca accccaagtg 1740 tcgctgagtt tttctaatct tccttttcta cagacccatc tgacctctcc cctcctcact 1800 aggccgagct aggtcccaat tcttcctcag cctctgctcc tccaccgtat aatcctttta 1860 tcacctcccc tcctcacacc cagtccggct tacagtttca ttccatgact agccctcccc 1920 cacctgccta gctatttcct cttaaaaagg tggctgaagc caaacgcata gtcaaggtta 1980 atactcattt ttctttatca gacctctccc aaatcagtga gcgtttaggc tctttcatca 2040 aatatgaaaa acccagccca gttcatggct cgtttggcgg caaccctgag acgctttaca 2100 gccctagacc ctaaaaagtc aaaaagccgt cttattctca atatacattt tattacccag 2160 tctgctcccg acattaaata aaactccaaa agttaaattc tggccctcaa accccacagc 2220 aggacttaat taacttcacc ttcaaggtgt acaataatag agtggaggca gccaagtagc 2280 aacatatttc tgagttgcaa ctctttgcct ccactgtgag acaaacccca gccacatctc 2340 cagcacacaa gaactccaaa cgcctgaacc gcagctgcca ggggttcctc cagaacctcc 2400 tcccccagga gcttgctaca agtgcccaca gcccaggatt cctcctgagc catgtcccat 2460 ctgtacagga ccccactgaa aattggactg ttcaactcac ctggcagcca cttccagagc 2520 ccctggaact ctggcccaag gccgtctgac tccttcccag atcttcttgg cttagcagct 2580 gaagactggc actgccgatc gccttggaag cctacaggac catcacagac actctaagta 2640 actctcacag tggaaagtaa gtccatcccc ttcttagtca atacggaggc tacccactcc 2700 acattacctt cttttcaagg gcctgtttcc cttgcctcca taactgttgt aaatattgac 2760 agccaggttc taaacctctt aaaactcccc aactctggtg ccaacttaga caatactctt 2820 ttaagcactc ctttttagtt atccccacct gcccagttcc cttattaggc ggagacactt 2880 taactaaatt atctgcttcc ctgactattc ctaggctaca tccacacctc attgccacct 2940 tttcccccag ttcaaagcct ccttcacatc ctccccttgt atctccccac cgtaacccac 3000 aagtataaga cacctctact ccctccttgg cgaccgatca tgcacccctt accatcccat 3060 taaaacctaa tcactcttac cccgctcaat gccaatatcc tatcccacag cacgctttga 3120 aaggattaaa gcctattatc acttgcctgt tagagcatgg ccttttaaag cctataaact 3180 cttcttacca ttcccccatt ttacctgtcc taaaaccaga caagccttac aggttagttc 3240 agaatctgcg ccttatcaac caaattgttt tgcctatcca ccccgtggtg ccaaacccat 3300 atactctcct atcctcaata cctccctcta caacccatta ttctgttctg gatctcaaac 3360 atgctttctt tactattcct ttgcaccctt catcccagcc tccctttgct ttcacttaga 3420 ctgaccctga cacccattag gctcagcaaa ttacctgggc tgtactgctg caaggcttca 3480 cagacagccc ccattacttc agtcaagccc aaatttcttc ctcatctgtt atctgtcttg 3540 gcgtaattct tataaaaaca cacgcgctct ccctgccgat cgtgtctgac tgatctctca 3600 aaccccaaca ccttctacaa cctaggcatg gttagatact ttcaacttta gatacctggt 3660 tttgccatcc taacaaaatc attatataaa ctcacaaaaa gaaacctagc tgaccccaca 3720 gatcctaaat cctttcccca ctcctttttc tgttccttga agacagcttt agagactgcc 3780 cccacctgag ctctccctga ctcatcccaa ccctttgcat tacacacagc caaagtgcag 3840 ggctgtgcag ttggaattct tacacaagga ccaggatcgc gtcctgtagc ctttttgccc 3900 aaacaacttg accttactgt tttaggctgg ccatcatgtc tctgtgcagt ggctactgac 3960 cctaatactt tcagaggccc ttaaaatcac aaactatgct caactcactc tctacagctc 4020 tcataatttc caaaatctat tttcttcctc acacctgatg catatacttt ctgctccccg 4080 gctccttcat ctctctgatc cagctgatgt tcacctcatt tccccacatt tccttcttcc 4140 ctgtttctca ccctgatcac acttagttta ttgatggcag ttccaccagg cctactcgcc 4200 acacaccagc aaagacaggc tatgctatag tacaagccac tagcctgcct tttagaacct 4260 ctcatttcct ttccatcgta gaaatctatc ctcaaggaaa taacttctca gcgttccatc 4320 tgctagtcta ctactcctca aggattattc aggccccctc ccttccctac acatcaagct 4380 caaggatttg cccccaccca ggactgacaa attagcttta ctcaacatgc cccgagtcaa 4440 gaaactaaaa tacctcttag tctaagtaga cactttcact gaataagtaa aggcctttcc 4500 tacaaggtct gagaaagcca ctgcggtcat ttcttccctt ctgtcagaca taattcctca 4560 gtttggactt cccacctcta tacagtccga tagcagaccc acctttatta gccaaatcag 4620 ccaagcattt tttcaggctc ttagtattca gtgaaacctt tatatccctt acagtcctca 4680 gtcttcagaa aaagtagaac agactaatag tcttaaaaac acacctcacc aagctcagcc 4740 accaacttaa aaaggactgg acaatacttt taccactttc ccttctcaga agtcagacct 4800 gtcctcagaa tactacaagg tgcagcccat ttgagctcct gtagagacac tcctttttat 4860 taggccccag tcttattcca gacaccagac caacttagac cgtgccccca aaaaacttgt 4920 catccctact atcttctgtc tagtcatact cctattcacc gttctcaact actcatacat 4980 gccctgctct tgtttacact gccggtttac actgtttctc caagccatca cagctgatat 5040 ctcctggtgc tatccccaaa ctgccactct taactcttga agtaaataaa gaatctttgc 5100 tgaccggact atgctgaatc tccttaggca ctctctaatc agatgtccta ggtcctccca 5160 attcttagac cttttatacc cgtttttctc cttctcttat tccatttagt ttttcaattc 5220 atacaaaacc atatccaggc cgtcaccaat aattctacac gacaaatgtt tcttctaaca 5280 accccacaat atcacccctt accacaaaat cttccttcag cttaatttct cccattctag 5340 gttcccacgc tgcccctaat cccacttgaa gcagccctaa gaaacatcac ccattatctc 5400 tccatgccat ccccaaaaaa ttttcaccat cccaacactt taccactctt tcgttttatt 5460 tttcttatta atataagaag acagaggccg ggcacggtgg ctcacgcctg taatcccagc 5520 actctgggag gccgaggcgg gcggatcacg aggtccggag atcgagacca tcctggctaa 5580 cacggtgaaa ccccgtttct actgaaaata caaaaaatta gctgggcgcc gtggcgggcg 5640 cctatagtcc cagctacttg ggaggctgag gcaggagaat ggcgtgaacc cgggaggcgg 5700 agcttgcagt gagccaagat agcgccactg cactccagcc tgggcgaaag agcgagactc 5760 cgtctcaaaa aaaaaaaaaa aaaaaagaca ggaatgtcag gcctctaagc cccagctaag 5820 ccatcatatc ccctgtgacc tgcacgtaca catccagatg gccggttcct gccttaactg 5880 atgacattcc accacaaaag aagtgaaaat ggcctgttcc tgccttaact gatgacattg 5940 tcttgtgaaa ttccttctcc tggctcatcc tggctcaaaa gctcccccac tgagtacctt 6000 gtgaccccca ctcctgcccg ccagagaaca accccccttt gactgtaatt ttcctttacc 6060 tacccaaatc ttataaaaag gccccactcc tatctccctt cgctgactct cttttcggac 6120 tcagctcgcc tgcacccagg tgaaataaac agctttattg ctcacacaaa gcctgtttag 6180 tggtctcttt acatggacgc aagtgaaa 6208

Claims (18)

  1. 환자에게서 취득한 생물학적 샘플에서 대장암을 시험관내에서 진단하거나 예후를 예측하는 방법으로서,
    2종 이상의 핵산 서열 각각의 발현 산물 2종을 검출하는 단계를 포함하며,
    상기 핵산 서열이 서열번호 1 - 285로 표시된 서열들로부터, 또는 서열번호 1 - 285로 표시된 서열들 중 하나의 서열과 99% 이상의 동일성을 나타내는 서열로부터 선택되는 것을 특징으로 하는 방법.
  2. 제1항에 있어서,
    2종 이상의 핵산 서열에 대한 발현 산물을 검출하며,
    상기 2종 이상의 핵산 서열이 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 표시된 서열들의 그룹, 또는 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 표시된 서열들과 99% 이상의 동일성을 나타내는 서열들로부터 선택되는 것을 특징으로 하는 방법.
  3. 제2항에 있어서,
    2종 이상의 핵산 서열, 바람직하게는 3종의 핵산 서열에 대한 발현 산물을 검출하며,
    상기 핵산 서열이 서열번호 2, 3 및 8로 표시된 서열들의 그룹, 또는 서열번호 2, 3 및 8로 표시된 서열들과 99% 이상의 동일성을 나타내는 서열들로부터 선택되는 것을 특징으로 하는 방법.
  4. 제1항에 있어서, 검출되는 상기 발현 산물이 1종 이상의 RNA 전사체 또는 1종 이상의 폴리펩타이드인 것을 특징으로 하는 방법.
  5. 제4항에 있어서, 상기 RNA 전사체가 1종 이상의 mRNA인 것을 특징으로 하는 방법.
  6. 제4항 또는 제5항에 있어서, 상기 RNA 전사체, 특히 mRNA는 혼성화, 증폭 또는 서열 분석에 의해 검출되는 것을 특징으로 하는 방법.
  7. 제6항에 있어서, mRNA를 혼성화가 가능한 소정의 조건 하에 1종 이상의 프로브 및/또는 1종 이상의 프라이머와 접촉시켜, 상기 mRNA에 대한 혼성화 유무를 검출하는 것을 특징으로 하는 방법.
  8. 제5항에 있어서,
    상기 mRNA의 DNA 카피를 제조하고,
    상기 DNA 카피를 혼성화가 가능한 소정의 조건 하에 1종 이상의 프로브 및/또는 1종 이상의 프라이머와 접촉시켜, 상기 DNA 카피에 대한 혼성화 유무를 검출하는 것을 특징으로 하는 방법.
  9. 제4항에 있어서, 상기 발현되는 폴리펩타이드는, 상기 폴리펩타이드에 대한 1종 이상의 특이적인 결합 파트너, 특히 항체 또는 항체 유사체, 친화성 단백질 또는 앱타머 (aptamer)와 접촉시키는 것에 의해 검출되는 것을 특징으로 하는 방법.
  10. 대장암을 시험관내에서 진단하거나 예후를 예측하기 위한 분자 마커로서의 분리된 2종 이상의 핵산 서열의 용도로서,
    상기 2종 이상의 핵산 서열이,
    (i) 서열번호 1 - 285의 서열로부터 선택되는, 바람직하게는 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 표시된 서열들로부터 선택되는, 특히 서열번호 2, 3 및 8의 서열들로부터 선택되는, 2종 이상의 DNA 서열, 또는
    (ii) 서열번호 1 - 285의 서열로부터 선택되는, 바람직하게는 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 표시된 서열들로부터 선택되는, 특히 서열번호 2, 3 및 8로 표시된 서열들로부터 선택되는, 2종 이상의 서열에 각각 상보적인, 2종 이상의 DNA 서열, 또는
    (iii) 상기 (i) 및 (ii)에 따른 2종의 서열과 99% 이상의 동일성을 나타내는, 2종 이상의 DNA 서열, 또는
    (iv) 상기 (i)에 따른 서열들로부터 선택되는 2종의 서열에 대한 각각의 전사 산물인, 2종 이상의 RNA 서열, 또는
    (v) 상기 (i)에 따른 서열들과 99% 이상의 동일성을 나타내는 서열들로부터 선택되는 2종 이상의 서열들에 대한 전사 산물인, 2종 이상의 RNA 서열로 구성되는 것을 특징으로 하는 방법.
  11. 환자에게서 취득한 생물학적 샘플에서 대장암을 시험관내에서 진단하거나 또는 예후를 예측하기 위한 키트로서,
    서열번호 1 - 285로 표시된 서열들로부터, 또는 서열번호 1 - 285로 표시되는 핵산 서열들과 99% 이상의 동일성을 나타내는 서열들로부터 선택되는, 2종 이상의 핵산 서열에 대한 2종 이상의 발현 산물 각각의 특이적인 결합 파트너 2종 이상 및 서열번호 1 - 285로 표시된 핵산 서열, 또는 서열번호 1 - 285로 표시된 핵산 서열들과 99% 이상의 동일성을 나타내는 핵산 서열의, 발현 산물에 대한 특이적인 결합 파트너 285종 이하를 포함하는 것을 특징으로 하는 키트.
  12. 제11항에 있어서,
    서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 표시된 서열들의 그룹으로부터, 또는 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 표시된 핵산 서열들과 99% 이상의 동일성을 나타내는 서열들로부터 선택되는, 2종 이상의 핵산 서열에 대한 발현 산물 각각의 특이적인 결합 파트너 2종 이상을 포함하는 것을 특징으로 하는 키트.
  13. 제12항에 있어서,
    서열번호 2, 3 및 8로 표시된 서열들의 그룹으로부터, 또는 서열번호 2, 3 및 8로 표시된 핵산 서열들과 99% 이상의 동일성을 나타내는 서열들로부터 선택되는, 2종 이상의 핵산 서열에 대한 발현 산물 각각의 특이적인 결합 파트너 2종 이상을 포함하는 것을 특징으로 하는 키트.
  14. 제12항에 있어서,
    서열번호 2, 3 및 8로 표시된 핵산 서열 또는 서열번호 2, 3 및 8로 표시된 서열과 99% 이상의 동일성을 나타내는 핵산 서열에 대한 발현 산물 각각의 특이적인 결합 파트너 2종 또는 3종을 포함하는 것을 특징으로 하는 키트.
  15. 제11항 내지 제14항 중 어느 한항에 있어서,
    상기 발현 산물 각각의 특이적인 결합 파트너 2종 이상은, 각각, 1종 이상의 혼성 프로브 및/또는 1종 이상의 증폭 프라이머, 1종 이상의 항체 또는 1종 이상의 항체 유사체, 1종 이상의 친화성 단백질 또는 1종 이상의 앱타머인 것을 특징으로 하는 키트.
  16. 대장암에서 치료 효능 및/또는 예후를 평가하는 방법으로서,
    2종 이상의 핵산 서열에 대한 각각의 발현 산물 2종 이상을 검출하는 단계를 포함하며,
    상기 2종의 핵산 서열이 서열번호 1 - 285로 표시된 서열들로부터, 또는 서열번호 1 - 285로 표시된 서열과 각각 99% 이상의 동일성을 나타내는 서열들로부터 선택되는 것을 특징으로 하는 방법.
  17. 제16항에 있어서,
    2종 이상의 핵산 서열에 대한 발현 산물을 검출하며,
    상기 2종 이상의 핵산 서열이 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 표시된 서열들의 그룹, 또는 서열번호 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19, 22, 24, 25, 27 및 97로 표시된 서열들과 99% 이상의 동일성을 나타내는 서열들로부터 선택되는 것을 특징으로 하는 방법.
  18. 제17항에 있어서,
    2종 이상, 바람직하게는 3종의 핵산 서열에 대한 발현 산물을 검출하며,
    상기 핵산 서열이 서열번호 2, 3 및 8로 표시된 서열들의 그룹, 또는 서열번호 2, 3 및 8로 표시된 서열들과 99% 이상의 동일성을 나타내는 서열들로부터 선택되는 것을 특징으로 하는 방법.
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