KR20140071272A - 항 당뇨병 펩타이드로서의 아포리포프로테인 ａｉｖ - Google Patents
항 당뇨병 펩타이드로서의 아포리포프로테인 ａｉｖ Download PDFInfo
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- KR20140071272A KR20140071272A KR1020137020637A KR20137020637A KR20140071272A KR 20140071272 A KR20140071272 A KR 20140071272A KR 1020137020637 A KR1020137020637 A KR 1020137020637A KR 20137020637 A KR20137020637 A KR 20137020637A KR 20140071272 A KR20140071272 A KR 20140071272A
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- apolipoprotein
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- apoa
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Classifications
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/575—Hormones
- C07K14/605—Glucagons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
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| PCT/US2012/021802 WO2012100010A1 (en) | 2011-01-19 | 2012-01-19 | Apolipoprotein aiv as an antidiabetic peptide |
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| ES2620404T3 (es) | 2011-01-19 | 2017-06-28 | University Of Cincinnati | Apoliproteína AIV como péptido antidiabético |
| EP2804618B1 (en) | 2012-01-19 | 2018-03-07 | University Of Cincinnati | Method of treating diabetes using non-glycosylated apolipoprotein a-iv |
| US9730980B2 (en) | 2012-07-25 | 2017-08-15 | University Of Cincinnati | Method of treating type I diabetes using apolipoprotein A-IV |
| US10232019B2 (en) | 2012-07-25 | 2019-03-19 | University Of Cincinnati | Method of treating hyperglycemic disorders using apolipoprotein AIV |
| CN112546201A (zh) * | 2019-09-26 | 2021-03-26 | 中国科学院生物物理研究所 | 人工脂蛋白颗粒apoA-Ⅳ脂肪体在治疗和/或预防糖尿病中的应用 |
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| FR2686605B1 (fr) * | 1992-01-27 | 1994-03-11 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides, leur preparation et leur utilisation. |
| AU7242394A (en) | 1993-05-28 | 1994-12-20 | Merck & Co., Inc. | Method to control appetite and treat obesity |
| WO2001077124A2 (en) * | 2000-04-05 | 2001-10-18 | Genaissance Pharmaceuticals, Inc. | Haplotypes of the apoa4 gene |
| PL374126A1 (en) | 2002-05-17 | 2005-10-03 | Esperion Therapeutics, Inc. | Methods and copositions for the treatment of ischemic reperfusion |
| US20100267052A1 (en) * | 2006-09-01 | 2010-10-21 | American Type Culture Collection | Compositions and methods for diagnosis and treatment of type 2 diabetes |
| AU2009226246A1 (en) * | 2008-03-21 | 2009-09-24 | Podiceps B.V. | Diagnostic of pre-symptomatic metabolic syndrome |
| CN103788043B (zh) | 2008-11-28 | 2016-02-03 | 中国医学科学院药物研究所 | 硝克柳胺化合物晶iv型、其制法和其药物组合物与用途 |
| ES2620404T3 (es) | 2011-01-19 | 2017-06-28 | University Of Cincinnati | Apoliproteína AIV como péptido antidiabético |
| EP2804618B1 (en) | 2012-01-19 | 2018-03-07 | University Of Cincinnati | Method of treating diabetes using non-glycosylated apolipoprotein a-iv |
| US9730980B2 (en) | 2012-07-25 | 2017-08-15 | University Of Cincinnati | Method of treating type I diabetes using apolipoprotein A-IV |
| US10232019B2 (en) | 2012-07-25 | 2019-03-19 | University Of Cincinnati | Method of treating hyperglycemic disorders using apolipoprotein AIV |
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| AU2012207301B2 (en) | 2016-05-19 |
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| CN103391786A (zh) | 2013-11-13 |
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| MX2013008374A (es) | 2013-12-06 |
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