KR20140038348A - 척추 유합 절차를 위한 조성물 및 방법 - Google Patents

척추 유합 절차를 위한 조성물 및 방법 Download PDF

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Publication number
KR20140038348A
KR20140038348A KR1020137015102A KR20137015102A KR20140038348A KR 20140038348 A KR20140038348 A KR 20140038348A KR 1020137015102 A KR1020137015102 A KR 1020137015102A KR 20137015102 A KR20137015102 A KR 20137015102A KR 20140038348 A KR20140038348 A KR 20140038348A
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South Korea
Prior art keywords
support material
bone support
composition
pdgf
micrometers
Prior art date
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Ceased
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KR1020137015102A
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English (en)
Korean (ko)
Inventor
사무엘 이. 린치
레오 비. 스넬
크리스토퍼 케이. 히
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바이오미메틱 세라퓨틱스, 엘엘씨
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Publication of KR20140038348A publication Critical patent/KR20140038348A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020137015102A 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법 Ceased KR20140038348A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42264910P 2010-12-13 2010-12-13
US61/422,649 2010-12-13
PCT/US2011/064698 WO2012082773A1 (en) 2010-12-13 2011-12-13 Compositions and methods for spine fusion procedures

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020187031242A Division KR20180121674A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법

Publications (1)

Publication Number Publication Date
KR20140038348A true KR20140038348A (ko) 2014-03-28

Family

ID=46245079

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1020137015102A Ceased KR20140038348A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법
KR1020207013423A Ceased KR20200055149A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법
KR1020187031242A Ceased KR20180121674A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법

Family Applications After (2)

Application Number Title Priority Date Filing Date
KR1020207013423A Ceased KR20200055149A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법
KR1020187031242A Ceased KR20180121674A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법

Country Status (10)

Country Link
US (2) US20140308332A1 (OSRAM)
EP (1) EP2651319A4 (OSRAM)
JP (3) JP6116484B2 (OSRAM)
KR (3) KR20140038348A (OSRAM)
CN (2) CN103491888A (OSRAM)
AU (1) AU2011343995A1 (OSRAM)
BR (1) BR112013014686A2 (OSRAM)
CA (1) CA2819258C (OSRAM)
MX (1) MX362405B (OSRAM)
WO (1) WO2012082773A1 (OSRAM)

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EP2654796A1 (en) 2010-12-21 2013-10-30 Koninklijke Philips N.V. Agents for clearing biomolecules from circulation
US20160082156A1 (en) * 2014-08-28 2016-03-24 Christopher G. WILSON Osteoinductive substrates and methods of making the same
MX2017004520A (es) 2014-10-14 2018-03-15 Lynch Samuel Composiciones para tratar heridas.
AU2015374114B2 (en) 2014-12-29 2018-07-26 Bioventus, Llc Systems and methods for improved delivery of osteoinductive molecules in bone repair
WO2017019959A1 (en) * 2015-07-30 2017-02-02 Clarion Research Group Formulations and methods for recovery from spinal surgery
US10300172B2 (en) 2015-10-30 2019-05-28 Bioventus, LLC. Matrix for enhanced delivery of osteoinductive molecules in bone repair
WO2017209823A2 (en) 2016-03-14 2017-12-07 The University Of Chicago Injectable pastes based on oppositely charged polymer/calcium phosphate hybrid nanoparticles
CA3026660A1 (en) 2016-06-10 2017-12-14 Bioventus, Llc Protein delivery with porous metallic structure
EP3651743B1 (en) * 2017-07-14 2023-10-04 The University of Chicago Freeze-dried formulations including nanoparticles and methods of freeze-drying
EP3938000A4 (en) * 2019-03-14 2022-11-16 BioMimetic Therapeutics, LLC PLATELET DERIVED GROWTH FACTOR FORMULATIONS TO IMPROVE BONE FUSION
EP3795185A1 (en) * 2019-09-23 2021-03-24 Kuros Biosurgery AG Bone graft material for use in a spinal fusion method
CN111481741A (zh) * 2020-04-15 2020-08-04 花沐医疗科技(上海)有限公司 复合可吸收自锁定颈椎融合器及其制备方法
KR102667977B1 (ko) 2020-05-08 2024-05-22 주식회사 에이치엘클레무브 차량용 레이더 장치 및 제어방법
WO2025042830A1 (en) 2023-08-18 2025-02-27 Biomimetic Therapeutics, Llc Platelet-derived growth factor bone graft putty formulation

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US20010037091A1 (en) * 1999-12-29 2001-11-01 Wironen John F. System for reconstituting pastes and methods of using same
ES2384405T3 (es) * 2000-10-24 2012-07-04 Warsaw Orthopedic, Inc. Dispositivos para fusionar vértebras
US20040230309A1 (en) * 2003-02-14 2004-11-18 Depuy Spine, Inc. In-situ formed intervertebral fusion device and method
US20040193270A1 (en) * 2003-03-31 2004-09-30 Depuyacromed, Inc. Implantable bone graft
CN1640368A (zh) * 2004-01-06 2005-07-20 宋跃明 椎间融合装置
US7901650B2 (en) * 2005-06-22 2011-03-08 Skeletal Kinectics, LLC Porous beta-tricalcium phosphate and methods for producing the same
WO2007061889A2 (en) * 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
AU2006326271B2 (en) * 2005-12-14 2011-02-24 Scil Technology Gmbh A moldable biomaterial for bone regeneration
US9161967B2 (en) * 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
US8106008B2 (en) * 2006-11-03 2012-01-31 Biomimetic Therapeutics, Inc. Compositions and methods for arthrodetic procedures
US8241357B2 (en) * 2007-04-25 2012-08-14 Jmea Corporation Prosthesis with a selectively applied bone growth promoting agent
US20090048675A1 (en) * 2007-04-25 2009-02-19 Bhatnagar Mohit K Spinal Fusion Implants with Selectively Applied Bone Growth Promoting Agent
CN101820895A (zh) * 2007-06-04 2010-09-01 生物模拟治疗公司 用于治疗脊柱的组合物和方法
CN101121753B (zh) * 2007-06-06 2011-11-16 天津林达生物科技有限公司 对多种皮肤细胞修复具持续作用的人血清白蛋白重组融合蛋白
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Also Published As

Publication number Publication date
JP2013545584A (ja) 2013-12-26
MX2013006697A (es) 2013-10-30
EP2651319A1 (en) 2013-10-23
WO2012082773A1 (en) 2012-06-21
CN103491888A (zh) 2014-01-01
US20190365946A1 (en) 2019-12-05
JP2018161541A (ja) 2018-10-18
CA2819258C (en) 2020-03-10
MX362405B (es) 2019-01-15
US20140308332A1 (en) 2014-10-16
JP6116484B2 (ja) 2017-04-19
CN108498873A (zh) 2018-09-07
BR112013014686A2 (pt) 2016-10-04
EP2651319A4 (en) 2016-08-17
AU2011343995A1 (en) 2013-06-20
JP2017018710A (ja) 2017-01-26
KR20180121674A (ko) 2018-11-07
KR20200055149A (ko) 2020-05-20
CA2819258A1 (en) 2012-06-21

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