KR20130095286A - 종양 줄기세포에서 eph 수용체의 발현 - Google Patents

종양 줄기세포에서 eph 수용체의 발현 Download PDF

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Publication number
KR20130095286A
KR20130095286A KR1020137011310A KR20137011310A KR20130095286A KR 20130095286 A KR20130095286 A KR 20130095286A KR 1020137011310 A KR1020137011310 A KR 1020137011310A KR 20137011310 A KR20137011310 A KR 20137011310A KR 20130095286 A KR20130095286 A KR 20130095286A
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South Korea
Prior art keywords
cells
gbm
epha2
ephrin
tumor
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Ceased
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KR1020137011310A
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English (en)
Korean (ko)
Inventor
안젤로 루이지 베스코비
엘레나 빈다
Original Assignee
스템젠 에스.피.에이.
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Publication of KR20130095286A publication Critical patent/KR20130095286A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Dermatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020137011310A 2010-10-01 2011-09-30 종양 줄기세포에서 eph 수용체의 발현 Ceased KR20130095286A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10185930A EP2446895A1 (en) 2010-10-01 2010-10-01 EPH receptor expression in tumor stem cells
EP10185930.4 2010-10-01
PCT/EP2011/067114 WO2012042021A1 (en) 2010-10-01 2011-09-30 Eph receptor expression in tumor stem cells

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020167002577A Division KR101719966B1 (ko) 2010-10-01 2011-09-30 종양 줄기세포에서 eph 수용체의 발현

Publications (1)

Publication Number Publication Date
KR20130095286A true KR20130095286A (ko) 2013-08-27

Family

ID=43856109

Family Applications (2)

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KR1020137011310A Ceased KR20130095286A (ko) 2010-10-01 2011-09-30 종양 줄기세포에서 eph 수용체의 발현
KR1020167002577A Active KR101719966B1 (ko) 2010-10-01 2011-09-30 종양 줄기세포에서 eph 수용체의 발현

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020167002577A Active KR101719966B1 (ko) 2010-10-01 2011-09-30 종양 줄기세포에서 eph 수용체의 발현

Country Status (11)

Country Link
US (1) US9078857B2 (cg-RX-API-DMAC10.html)
EP (2) EP2446895A1 (cg-RX-API-DMAC10.html)
JP (4) JP2013540117A (cg-RX-API-DMAC10.html)
KR (2) KR20130095286A (cg-RX-API-DMAC10.html)
AU (1) AU2011310109B2 (cg-RX-API-DMAC10.html)
CA (1) CA2813101C (cg-RX-API-DMAC10.html)
DK (1) DK2621513T3 (cg-RX-API-DMAC10.html)
ES (1) ES2616444T3 (cg-RX-API-DMAC10.html)
NZ (1) NZ609594A (cg-RX-API-DMAC10.html)
PL (1) PL2621513T3 (cg-RX-API-DMAC10.html)
WO (1) WO2012042021A1 (cg-RX-API-DMAC10.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH12013501137A1 (en) 2010-12-08 2021-06-02 Abbvie Stemcentrx Llc Novel modulators and methods of use
SA112330278B1 (ar) 2011-02-18 2015-10-09 ستيم سينتركس، انك. مواد ضابطة جديدة وطرق للاستخدام
EP2733206A1 (en) * 2012-11-19 2014-05-21 Naroa LLC Method for the isolation for mammalian stem cells using EphA2 and uses thereof
RU2016119491A (ru) 2013-11-04 2017-12-11 Пфайзер Инк. Конъюгаты антитела к efna4 с лекарственным средством
SMT202100146T1 (it) 2014-04-30 2021-05-07 Pfizer Coniugati di anticorpo anti-ptk7-farmaco
ES2796973T3 (es) 2014-12-10 2020-11-30 Hyperstem Sa Métodos y composiciones para reducir el crecimiento, la migración y la invasividad de células madre de cáncer cerebral y mejorar la supervivencia de pacientes con tumores cerebrales
US10783439B2 (en) * 2015-05-08 2020-09-22 FlowJo, LLC Plugin interface and framework for integrating a remote server with sample data analysis software
WO2017081686A1 (en) 2015-11-10 2017-05-18 B. G. Negev Technologies And Applications Ltd., At Ben-Gurion University Means and methods for reducing tumorigenicity of cancer stem cells
US20240226175A1 (en) * 2020-03-31 2024-07-11 Keio University Therapeutic agent using genome-edited pluripotent stem cell
WO2026022122A1 (en) * 2024-07-23 2026-01-29 Eos Research Sa Checkpoint inhibitors in the treatment of glioblastoma multiforme

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060130038A (ko) * 2003-10-15 2006-12-18 메디뮨 인코포레이티드 리스테리아에 의거한 ＥｐｈＡ２ 백신
AU2005277641A1 (en) * 2004-08-16 2006-03-02 Medimmune, Llc Eph receptor Fc variants with enhanced antibody dependent cell-mediated cytotoxicity activity
US20070248628A1 (en) * 2005-12-06 2007-10-25 Keller Lorraine H Immunogens in cancer stem cells
US8343461B2 (en) * 2006-03-08 2013-01-01 Wake Forest University Health Sciences Molecular signature of cancer
WO2009028639A1 (ja) * 2007-08-30 2009-03-05 Daiichi Sankyo Company, Limited 抗ｅｐｈａ２抗体

Also Published As

Publication number Publication date
AU2011310109A1 (en) 2013-05-02
DK2621513T3 (en) 2017-03-06
JP2018048151A (ja) 2018-03-29
WO2012042021A1 (en) 2012-04-05
EP2621513B1 (en) 2016-12-28
JP6523910B2 (ja) 2019-06-05
CA2813101C (en) 2018-10-30
US9078857B2 (en) 2015-07-14
JP2020037579A (ja) 2020-03-12
JP6618968B2 (ja) 2019-12-11
KR101719966B1 (ko) 2017-03-24
JP2016094391A (ja) 2016-05-26
PL2621513T3 (pl) 2017-06-30
AU2011310109B2 (en) 2014-11-20
JP2013540117A (ja) 2013-10-31
US20120083454A1 (en) 2012-04-05
ES2616444T3 (es) 2017-06-13
NZ609594A (en) 2015-01-30
KR20160027106A (ko) 2016-03-09
EP2621513A1 (en) 2013-08-07
CA2813101A1 (en) 2012-04-05
EP2446895A1 (en) 2012-05-02

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