KR20130043710A - Illite effluent in progressive metamorphism, its producing method and cosmetic composition for skin disease including it - Google Patents

Abstract

PURPOSE: An eluate from a progressive metamorphism of an illite, a manufacturing method thereof, and a cosmetic composition including the same for skin disease prevention are provided to reduce energy and time for processing by removing the necessity of finely grinding illite. CONSTITUTION: A manufacturing method of an eluate from a progressive metamorphism of illite comprises the following steps: a step of putting 2-95 weight% of illite and 5-98 weight% of water into a closed container, and heating at 90-400 deg. C; a step of maintaining the temperature at 90-400 deg. C for 1-10 hours after completely closing the container; and a step of collecting and condensing steam which is discharged when the container is opened. The steam is generated by heating the water in the container.

Description

Illite effluent in progressive metamorphism, its producing method and cosmetic composition for skin disease including it}

The present invention relates to an eluate that is eluted during the advancing metamorphism of the illite, and the component is eluted in the process of gradually adapting to the elevated temperature by gradually raising the temperature of the illite with water in a closed container. The present invention relates to an eluting solution eluted during an advancing metamorphism of illite, a preparation method thereof, and a cosmetic composition for improving skin diseases including the same.

Illite is a mica mineral belonging to monoclinic system. Since it adsorbs suspended matter in water and has an anion, it is caused by flocculation of fine particles and electric neutralization, causing coagulation and precipitation to clean water, and various heavy metals and organic matter on the skin. Adsorption and decomposition of substances and toxic substances.

Applications for atopic dermatological ointments and cosmetics including illite using the efficacy of the illite have already been published, these prior art is to allow the illite mineral existing as a rock to be absorbed by the skin It is ground to a size less than 100 nanometers and mixed with other ingredients to be processed into the form of ointment, cream, etc.

However, in order to crush the illite mineral to less than 100 nanometers, there is a problem that the grinding cost is high, and the crushed illite is not smooth during skin contact. In addition, products containing illite powder have a large amount of illite because it is difficult to penetrate the skin because the illite component has a powder form, even if it contains a large amount of illite, such as an ointment It was also unclear whether there was sufficient effect on this atopy.

In addition, in order to overcome this problem, it may be considered to simply extract the illite mineral in water, but the components obtained by stirring the illite mineral in water may not extract the active ingredients necessary for the treatment of skin diseases. There was a problem.

The present invention has been invented to solve the above problems, the present invention includes the components eluted in the process of gradually adapting to the elevated temperature by putting the illite with water in a sealed container and gradually raising the temperature. It is an object of the present invention to provide an eluting solution eluted during the advancing metamorphism of the illite, a preparation method thereof and a cosmetic composition for improving skin diseases including the same.

The eluate eluted in the forward metamorphism of the illite according to the present invention is placed in an airtight container with water and heated to maintain a temperature of 90-400 ° C. for 1 to 10 hours, and then the vapor generated by opening the container. It is characterized by obtaining by condensation.

Eluent preparation method eluted in the forward modification of the illite according to the present invention comprises a heating step of heating 2-95% by weight of illite and 5-98% by weight of water in a sealed container to 90-400 ℃; Maintaining the container for 1 to 10 hours at a temperature of 90-400 ° C in a sealed state; And a condensation step of collecting and condensing water vapor coming out while opening the sealed container.

Eluent preparation method eluted in the further modification of the illite according to the present invention is a steam generation step of generating water vapor by putting 5-98% by weight of water in a container and heated to 90-400 ℃; An eluting step of bringing the water vapor into contact with 2-95 wt% of illite; And a condensation step of collecting and condensing the water vapor passed through the elution step.

Cosmetic composition for improving skin diseases comprising an eluted solution eluted in the forward metamorphism of the illite according to the present invention is maintained by heating the illite and water in a closed container for 1 to 10 hours at a temperature of 90-400 ℃ Then, the eluate is obtained by condensing water vapor generated by opening the closed container.

The effects of the present invention are summarized below.

1) Specificity of ingredients

The eluate according to the present invention contains a component eluting in the process of adapting to the temperature of the elite gradually rising, which is different from the components that can be obtained by simply putting the elite in water and stirring.

2) Excellent skin disease treatment effect

Due to the difference in the components described above, the eluate according to the present invention shows an excellent effect on improving skin diseases, and also elutes only the active ingredient of the illite, very little effect as the product containing a large amount of fine illite powder Can also be expected in quantity.

3) The manufacturing cost is low

To absorb the components of the illite into the skin, the illite can be processed to less than 70 nanometers to allow the illite to penetrate deep into the skin, or finely pulverize the illite with a large surface area per unit weight. In addition, the active ingredients of the illite must penetrate into the water or oil contained in the cosmetics. However, since the illite eluate according to the method of the present application does not need to finely process the illite, energy and time required for processing can be saved, so that the illite eluate can be produced at low cost.

4) There is no single side effect

The illite eluate according to the present invention is safe enough to show no side effects even in a single person as shown in the clinical trials described below.

5) In the world, skin disease patients such as acne or atopy are on the rise, illite rocks are rare rocks, and only Korea has a significant amount of industrially developed deposits, which can contribute to foreign currency acquisition in the future.

The illite eluate according to the present invention contains the components eluted during the advance modification of the illite. The illite's forward denaturation process causes the illite to elute a large amount of Fe, Mn, Mg, K, Na, Ca, and Al in the process of adjusting the temperature gradually in the region where the temperature rises. They are different from the components eluted through weathering at normal room temperature.

The eluate in the present invention is obtained by placing the illite and water in a sealed container and heating to maintain a temperature of 90-400 ℃ for 1 to 10 hours, and then condensing the water vapor generated by opening the sealed container.

Hereinafter, the manufacturing method of the illite eluate according to the present invention will be described in detail. The production method of the illite eluate according to the present invention includes a heating step, a holding step, a condensation step.

In the heating step, the illite and water are put into a closed container and heated.

Here, it is preferable to use the illite powder grind | pulverized to small size here. However, since the illite powder itself is not directly mixed with a cream or an ointment as in the conventional products, it is not necessary to grind very finely. The illite powder preferably has a size of 0.00001 to 0.25 mm. If it is less than 0.00001mm, there is a problem that the crushing cost burden becomes large, and if it exceeds 0.25mm, the surface area in contact with water is relatively small, so that dissolution is not performed properly. Since the grinding of the illite mineral may use a conventional grinding method of the mineral, it will not be described in detail here.

Although water may be used as usual, distilled water is preferably used when the eluate according to the present invention is finally used as a cosmetic composition for improving skin diseases.

The mixing ratio of illite and water is mixed in the ratio of 2-95 wt% of illite and 5-98 wt% of water. If the illite content is less than 2% by weight, there is a problem that the mineral content of the eluted solution is too small, and even if the illite content exceeds 95% by weight, the illite content in the eluate does not change significantly.

In the heating step, the temperature of the closed vessel is raised to 90 ~ 400 ℃. If it is less than 90 ℃ the ratio of the minerals eluted in the holding step is different, usually the same as the components that can be obtained by simply stirring the mixture of water and illite at room temperature can not achieve the desired purpose desired in the present invention There is a problem that the illite is denatured when it exceeds 400 ℃.

In addition, since the present invention aims to obtain the maximum component eluted during the advance modification of the illite, it is preferable that the temperature increase in the heating step proceeds slowly at a rate of 1 ° C./minute to 50 ° C./minute. If the temperature rise exceeds 50 ° C / min, the illite component changes due to melting of the illite near the heat source in the process of transferring heat to the near and far side of the heat source, and if the temperature rise is less than 1 ° C / min. There is a problem that the production process takes too long.

The holding step is a step of eluting the active ingredients in the illite into the water while maintaining the temperature of 90 ~ 400 ℃ for 1 to 10 hours in a closed state of the closed container heated in the heating step.

In the holding step, the temperature of the closed container is maintained at 90-400 ° C., but preferably, the temperature heated in the heating step is maintained as it is.

The maintenance step is preferably performed for 1-10 hours. If the elution time is less than 1 hour, the eluate has a thin problem. If the elution time is more than 10 hours, there is almost no change in the amount of minerals eluted.

In addition, since the present invention proceeds in a closed container, this creates a high pressure as well as a high temperature, thereby forming a condition similar to the condition that the metamorphic process of the rock in the basement, the eluate having a different composition from the extract at normal room temperature Can be prepared.

In the condensation step, a closed container is slowly opened to collect and vaporize water vapor while maintaining the temperature in the container. Here, it is preferable that the temperature of the hermetically sealed container is maintained at a high temperature even while collecting steam. Since the condensation method may use a conventional method, detailed description is omitted here.

In addition to the above-described manufacturing method it is also possible to prepare an eluate which is eluted in the course of the advance metamorphism of the illite.

The method for producing an eluate eluted in the forward modification of another illite according to the present invention includes a steam generation step, an elution step and a condensation step.

Steam generation step is a step of generating water vapor by heating 5-98% by weight of water in a container to 90-400 ℃. The generation of water vapor here may be generated at atmospheric pressure, but may also be generated under pressure.

The eluting step is a step of eluting the active ingredient by contacting the generated steam with 2-95 wt% of illite. The elution step can also be carried out at atmospheric pressure, but it is preferable to carry out under pressure. The pressure here proceeds under 1 to 200 atmospheres. If the pressure is less than 1 atm, it is difficult to maintain the pressure when heat is applied. If the pressure is more than 200 atm, elution is impossible due to excessive pressure.

Since the condensation step has been described in detail above, a description thereof will be omitted.

The eluate eluted during the advance denaturation of the illite obtained through this process is different from the components that can be obtained by putting the illite into water at room temperature, as shown in the following Examples and Comparative Examples. The illite eluate obtained through the process shows an excellent effect on improving skin diseases unlike the conventional products.

Meanwhile, the illite eluate may contain various moisturizing ingredients or other active ingredients. Examples of the moisturizing ingredient include silk amino acid or glycerin. In this case, it is preferable to add 0.1-2 weight part of silk amino acids or 0.1-20 weight part of glycerin based on 100 weight part of illite eluate.

In addition, the eluate according to the present invention has an excellent effect in improving skin diseases including acne and atopy, and in order to supplement these effects, one or more of tea tree antibacterial agent, squalene, silver nanowater, propolis, and silk amino acid may be used. 100 parts by weight of the light eluate may be further included in a ratio of 0.1-5 parts by weight. Tea tree antimicrobial agent is made by extracting only Terpinen-4-ol, which is the most contained in tea tree, squalene is liver oil extracted from liver of deep sea shark, and silver nano water is 99.9% of silver nano, which has strong antibacterial activity. It is a liquid, propolis is a kind of adhesive that honey bees use when building honeycombs, and silkamino acid is an amino acid contained in a protein called fibroin, the main component of cocoon.

The cosmetic composition for improving skin diseases according to the present invention contains the above-mentioned elite eluate component as a main component, and the cosmetic composition for improving skin diseases is not particularly limited in its form. For example, it may be prepared in the form of ointment, lotion, cream, skin, shampoo, solid soap, liquid soap and the like. The manufacturing method of such a product uses a conventional manufacturing method, but since the above example is a procedure for replacing the distilled water (pure water) in the aqueous phase components of the product with an illite eluate, detailed description thereof will be omitted here.

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Hereinafter, the present invention will be described with reference to Examples.

1. Eluent Component Comparison

In order to compare the components of the illite eluate according to the present invention with the illite powder and the extract at room temperature, the following experiment was conducted.

end. Preparation of Sample

1) Example 1

The elite mineral was pulverized to a diameter of 0.1-0.5 mm, 500 g of the pulverized elite mineral and 1000 g of water were placed in a closed container and heated to 230 ° C. at a rate of 10 ° C./min, in which state 230 was After maintaining the temperature at 占 폚, the sealed container was opened to collect water vapor, and the water vapor was condensed in a bath containing cold water to obtain an illite eluate, and the powder remaining in the sealed container was subjected to component analysis.

2) Comparative Example 1

The illite minerals were pulverized to a diameter of 0.1-0.5 mm to perform component analysis of the illite powder itself.

3) Comparative Example 2

The elite mineral was pulverized to a diameter of 0.1-0.5 mm, 500 g of pulverized elite mineral and 1000 g of water were put in a container, stirred at a speed of 20,000 rpm for 200 hours at room temperature, and filtered to analyze the remaining powder.

Analysis ingredient Example Comparative Example 1 Comparative Example 2 Fe 15,794 18,848 17,688 Mn 328 486 396 Si 312,900 319,200 297,150 Mg 1,669 2,371 2,038 K 17,850 22,010 22,329 Na 5,930 6,566 6,396 Ca 507 1,155 736 Ti 2,026 2,037 1,868 P 149 152 142 Al 75,126 94,878 102,474

unit ; ppm

Analysis method: Inductively Coupled Plasma Spectrometer (ICP)

-Pretreatment: Add sample and mixed acid (nitric acid, hydrofluoric acid) and heat decompose at high temperature.

-Condition after pretreatment: Completely soluble

Analyzer: Perkin-elmer Optima 2100DV

Analytical elements: Fe, Mn, Si, Mg, K, Na, Ca, Ti, P, Al

Standard materials: Fe, Mn, Si, Mg, K, Na, Ca, Ti, P, Al

As can be seen from the above analysis results, the case of simply stirring at room temperature for a long time (Comparative Example 2) and eluting at high temperature as in the present invention (Example 1) are compared with the illite mineral itself (Comparative Example 1). ,

In Comparative Example 2, a lot of Si, Ti, and P components were extracted in comparison with Example 1, whereas in Example 1, Fe, Mn, Mg, K, Na, Ca, and Al components were relatively higher than in Comparative Example 2. Much was eluted.

2. Eluent Efficacy Comparison

end. Preparation of Sample

1) Example 2

The elite mineral was pulverized to a diameter of 0.1-0.5 mm, 500 g of the pulverized elite mineral and 1000 g of water were placed in a closed container and heated to 150 ° C. at a rate of 10 ° C./min, and in that state 150 for 1 hour. After maintaining the temperature at 占 폚, the closed vessel was opened to collect water vapor, and the water vapor was condensed in a bath containing cold water to obtain an illite eluate.

2) Example 3

The elite mineral was pulverized to a diameter of 0.1-0.5 mm, 500 g of the pulverized elite mineral and 1000 g of water were placed in a closed container and heated to 150 ° C. at a rate of 10 ° C./min, and in that state 150 for 2 hours. After maintaining the temperature at 占 폚, the closed vessel was opened to collect water vapor, and the water vapor was condensed in a bath containing cold water to obtain an illite eluate.

3) Example 4

The elite mineral was pulverized to a diameter of 0.1-0.5 mm, 500 g of the pulverized elite mineral and 1000 g of water were placed in a sealed container and heated to 230 ° C. at a rate of 10 ° C./min, and in that state, 230 After maintaining the temperature at 占 폚, the closed vessel was opened to collect water vapor, and the water vapor was condensed in a bath containing cold water to obtain an illite eluate.

4) Example 5

The elite mineral was pulverized to a diameter of 0.1-0.5 mm, 500 g of the pulverized illite mineral and 1000 g of water were placed in a closed container and heated to 230 ° C. at a rate of 10 ° C./min, and in that state 230 for 2 hours. After maintaining the temperature at 占 폚, the closed vessel was opened to collect water vapor, and the water vapor was condensed in a bath containing cold water to obtain an illite eluate.

5) Example 6

The elite mineral was pulverized to a diameter of 0.1-0.5 mm, 500 g of pulverized elite mineral and 1000 g of water were placed in a closed container and heated to 230 ° C. at a rate of 10 ° C./min, and in that state, 230 After maintaining the temperature at 占 폚, the closed vessel was opened to collect water vapor, and the water vapor was condensed in a bath containing cold water to obtain an illite eluate.

6) Example 7

The elite mineral was pulverized to a diameter of 0.1-0.5 mm, 500 g of the pulverized elite mineral and 1000 g of water were placed in a closed container and heated to 230 ° C. at a rate of 10 ° C./min, and 230 for 4 hours. After maintaining the temperature at 占 폚, the closed vessel was opened to collect water vapor, and the water vapor was condensed in a bath containing cold water to obtain an illite eluate.

7) Comparative Example 3

The elite mineral was pulverized to a diameter of 0.1-0.5 mm, 500 g of pulverized elite mineral and 1000 g of water were put in a container, stirred at a speed of 18,000 rpm for 10 hours at room temperature, and filtered to obtain a liquid.

8) Comparative Example 4

The elite mineral was pulverized to a diameter of 0.1-0.5 mm, 500 g of pulverized elite mineral and 1000 g of water were put in a container, stirred at a speed of 18,000 rpm for 20 hours at room temperature, and filtered to obtain a liquid.

I. Clinical trial

Men and women with acne symptoms 13 to 43 years old (including pregnant women) to select a number of cotton, papules, pustules according to each condition divided into the elite extract and eluate obtained in the above examples and comparative examples twice a day morning and night It was applied later.

In the experimental group with acne, all participants had cotton wool, and most of them had pustules and papules.

As a result of the experiment, the fast person began to improve on the third day, and a month later, the results of the survey and the improvement of the symptoms of the participants were as follows.

None of the cases complained of adverse effects during the above experiments, indicating the safety of the illite extract.

Claims (6)

Elite and water are put in an airtight container and heated for 1 to 10 hours at a temperature of 90-400 ° C., and then eluted in the forward metamorphism of the illite, which is obtained by condensing water vapor generated by opening the container. Eluent. A heating step of heating 2-95% by weight of illite and 5-98% by weight of water to a closed container and heating to 90-400 ° C .;
Maintaining the container for 1 to 10 hours at a temperature of 90-400 ° C in a sealed state;
And a condensation step of collecting and condensing water vapor coming out while opening the sealed container. A steam generating step of adding 5-98 wt% of water to a container and heating to 90-400 ° C. to generate steam;
An eluting step of bringing the water vapor into contact with 2-95 wt% of illite;
And a condensation step of collecting and condensing the water vapor passed through the elution step. 3. The method of claim 2, wherein in the holding step, the eluted solution is eluted in the advancing metamorphism of the illite, wherein the temperature heated in the heating step is maintained as it is. 4. The method of claim 2 or 3, wherein the illite is pulverized to a size of 0.00001 ~ 2.5mm eluting in the elution of the forward modification of the illite. Illite and water in an airtight container and heated to maintain a temperature of 90-400 ℃ for 1 to 10 hours, the illite comprising a eluate obtained by condensing the water vapor generated by opening the closed container Cosmetic composition for improving skin diseases comprising the eluate eluted in the forward metamorphism of.